Search of human proteins with 46255026

Search of human proteins with 46255026

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46255026 potassium channel tetramerisation domain containing
3 [Homo sapiens]
         (815 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46255026 potassium channel tetramerisation domain containing ...  1640   0.0  
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                 844   0.0  
gi|169234778 potassium channel tetramerisation domain containing...    86   2e-16
gi|71143104 potassium channel tetramerisation domain containing ...    80   1e-14
gi|53829365 potassium channel tetramerisation domain containing ...    76   1e-13
gi|189571693 potassium channel tetramerisation domain containing...    74   7e-13
gi|189571691 potassium channel tetramerisation domain containing...    74   7e-13
gi|9506651 potassium channel tetramerisation domain containing 5...    72   2e-12
gi|23308551 potassium channel tetramerisation domain containing ...    67   7e-11
gi|146198864 potassium channel tetramerisation domain containing...    62   3e-09
gi|39753959 potassium channel tetramerisation domain containing ...    59   2e-08
gi|142356950 potassium channel tetramerisation domain containing...    58   3e-08
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       58   4e-08
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       58   4e-08
gi|38198663 potassium channel tetramerisation domain containing ...    58   4e-08
gi|55926200 potassium channel tetramerisation domain containing ...    56   1e-07
gi|19923973 potassium channel tetramerisation domain containing ...    56   2e-07
gi|27436984 potassium voltage-gated channel, Shal-related subfam...    55   3e-07
gi|27436986 potassium voltage-gated channel, Shal-related subfam...    55   3e-07
gi|194018443 potassium channel tetramerisation domain containing...    55   3e-07
gi|194018441 potassium channel tetramerisation domain containing...    55   3e-07
gi|194018439 potassium channel tetramerisation domain containing...    55   3e-07
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    55   3e-07
gi|45387953 potassium channel tetramerization domain containing ...    54   4e-07
gi|27436981 potassium voltage-gated channel, Shal-related subfam...    53   1e-06
gi|13994353 potassium channel tetramerisation domain containing ...    52   3e-06
gi|24497460 Shaw-related voltage-gated potassium channel protein...    51   4e-06
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    50   8e-06
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    49   1e-05
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    49   1e-05

>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 1640 bits (4248), Expect = 0.0
 Identities = 815/815 (100%), Positives = 815/815 (100%)

Query: 1   MAGGHCGSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETG 60
           MAGGHCGSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETG
Sbjct: 1   MAGGHCGSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETG 60

Query: 61  AIFIDRDPAAFAPILNFLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSC 120
           AIFIDRDPAAFAPILNFLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSC
Sbjct: 61  AIFIDRDPAAFAPILNFLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSC 120

Query: 121 GSVLFHGYLPPPGIPSRKINNTVRSADSRNGLNSTEGEARGNGTQPVLSGTGEETVRLGF 180
           GSVLFHGYLPPPGIPSRKINNTVRSADSRNGLNSTEGEARGNGTQPVLSGTGEETVRLGF
Sbjct: 121 GSVLFHGYLPPPGIPSRKINNTVRSADSRNGLNSTEGEARGNGTQPVLSGTGEETVRLGF 180

Query: 181 PVDPRKVLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVG 240
           PVDPRKVLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVG
Sbjct: 181 PVDPRKVLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVG 240

Query: 241 GPHGDKDKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKV 300
           GPHGDKDKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKV
Sbjct: 241 GPHGDKDKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKV 300

Query: 301 GVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELY 360
           GVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELY
Sbjct: 301 GVWNAVTQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELY 360

Query: 361 HDPSNDAITALSVYLTPKTSVSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVH 420
           HDPSNDAITALSVYLTPKTSVSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVH
Sbjct: 361 HDPSNDAITALSVYLTPKTSVSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVH 420

Query: 421 RSPVTKIMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHG 480
           RSPVTKIMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHG
Sbjct: 421 RSPVTKIMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHG 480

Query: 481 SYSSGNDIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRE 540
           SYSSGNDIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRE
Sbjct: 481 SYSSGNDIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRE 540

Query: 541 CEGSSRMGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSEDKDVGGPTEEELLKLLDQCD 600
           CEGSSRMGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSEDKDVGGPTEEELLKLLDQCD
Sbjct: 541 CEGSSRMGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSEDKDVGGPTEEELLKLLDQCD 600

Query: 601 LSTSRCATPNISPATSVVQHSHLRESNSSLQLQHHDTTHEAATYGSMRPYRESPLLARAR 660
           LSTSRCATPNISPATSVVQHSHLRESNSSLQLQHHDTTHEAATYGSMRPYRESPLLARAR
Sbjct: 601 LSTSRCATPNISPATSVVQHSHLRESNSSLQLQHHDTTHEAATYGSMRPYRESPLLARAR 660

Query: 661 RTESFHSYRDFQTINLNRNVERAVPENGNLGPIQAEVKGATGECNISERKSPGVEIKSLR 720
           RTESFHSYRDFQTINLNRNVERAVPENGNLGPIQAEVKGATGECNISERKSPGVEIKSLR
Sbjct: 661 RTESFHSYRDFQTINLNRNVERAVPENGNLGPIQAEVKGATGECNISERKSPGVEIKSLR 720

Query: 721 ELDSGLEVHKIAEGFSESKKRSSEDENENKIEFRKKGGFEGGGFLGRKKVPYLASSPSTS 780
           ELDSGLEVHKIAEGFSESKKRSSEDENENKIEFRKKGGFEGGGFLGRKKVPYLASSPSTS
Sbjct: 721 ELDSGLEVHKIAEGFSESKKRSSEDENENKIEFRKKGGFEGGGFLGRKKVPYLASSPSTS 780

Query: 781 DGGTDSPGTASPSPTKTTPSPRHKKSDSSGQEYSL 815
           DGGTDSPGTASPSPTKTTPSPRHKKSDSSGQEYSL
Sbjct: 781 DGGTDSPGTASPSPTKTTPSPRHKKSDSSGQEYSL 815


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score =  844 bits (2180), Expect = 0.0
 Identities = 427/630 (67%), Positives = 494/630 (78%), Gaps = 22/630 (3%)

Query: 17  GEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILN 76
           GE++ LNVGG RFSTSRQTL WIPDSFFSSLLSGRISTL+DETGAIFIDRDP  FAPILN
Sbjct: 18  GEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILN 77

Query: 77  FLRTKELDLRGVSINVLRHEAEFYGITPLVRRLLLCEELERSSCGSVLFHGYLPPPGIPS 136
           FLRTKELD RGV  + L HEA+FYG+TPLVRRL L EEL+RSSCG+VLF+GYLPPP  P 
Sbjct: 78  FLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELDRSSCGNVLFNGYLPPPVFPV 137

Query: 137 RKINNTVRSADSRNGLNSTEGEARGNGTQPVLSGTGEETVRL----------GFPVDPRK 186
           ++ N    S      L       R + T P   G      R+          G P +P  
Sbjct: 138 KRRNR--HSLVGPQQLGGRPAPVRRSNTMPPNLGNAGLLGRMLDEKTPPSPSGQPEEPGM 195

Query: 187 VLIVAGHHNWIVAAYAHFAVCYRIKESSGWQQVFTSPYLDWTIERVALNAKVVGGPHGDK 246
           V +V GHHNWI  AY  F VCYR+KE+SGWQ VF+SP LDW IER+AL A+V GG  G+ 
Sbjct: 196 VRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSPRLDWPIERLALTARVHGGALGEH 255

Query: 247 DKMVAVASESSIILWSVQDGGSGSEIGVFSLGVPVDALFFIGNQLVATSHTGKVGVWNAV 306
           DKMVA A+ S I+LW++Q  G GSEIGVF LGVPV+ALFF+GNQL+ATSHTG++GVWNAV
Sbjct: 256 DKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAV 315

Query: 307 TQHWQVQDVVPITSYDTAGSFLLLGCNNGSIYYIDMQKFPLRMKDNDLLVTELYHDPSND 366
           T+HWQVQ+V PITSYD AGSFLLLGCNNGSIYY+D+QKFPLRMKDNDLLV+ELY DP+ D
Sbjct: 316 TKHWQVQEVQPITSYDAAGSFLLLGCNNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAED 375

Query: 367 AITALSVYLTPKTSVSGNWIEIAYGTSSGAVRVIVQHPETVGSGPQLFQTFTVHRSPVTK 426
            +TALSVYLTPKTS SGNWIEIAYGTSSG VRVIVQHPETVGSGPQLFQTFTVHRSPVTK
Sbjct: 376 GVTALSVYLTPKTSDSGNWIEIAYGTSSGGVRVIVQHPETVGSGPQLFQTFTVHRSPVTK 435

Query: 427 IMLSEKHLVSVCADNNHVRTWTVTRFRGMISTQPGSTPLASFKILSLEETESHGSYSSGN 486
           IMLSEKHL+SVCADNNHVRTW+VTRFRGMISTQPGSTPLASFKIL+LE  + HG  S+GN
Sbjct: 436 IMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGHGGCSAGN 495

Query: 487 DIGPFGERDDQQVFIQKVVPITNKLFVRLSSTGKRICEIQAVDCTTISSFTVRECEGSSR 546
           DIGP+GERDDQQVFIQKVVP  ++LFVRLSSTG+R+C +++VD +  ++FTV ECEGS R
Sbjct: 496 DIGPYGERDDQQVFIQKVVPSASQLFVRLSSTGQRVCSVRSVDGSPTTAFTVLECEGSRR 555

Query: 547 MGSRPRRYLFTGHTNGSIQMWDLTTAMDMVNKSEDKDVGGPTEEELLKLLDQCDL----- 601
           +GSRPRRYL TG  NGS+ MWDLTTAMD + ++     GG TE+EL++ L+ C+L     
Sbjct: 556 LGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQA---PAGGLTEQELMEQLEHCELAPPAP 612

Query: 602 -STSRCATPNISPATSVVQHSHLRESNSSL 630
            + S    P+ SP  S+    H   SN+SL
Sbjct: 613 SAPSWGCLPSPSPRISLTS-LHSASSNTSL 641


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 53/103 (51%), Positives = 65/103 (63%), Gaps = 2/103 (1%)

Query: 7   GSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGR-ISTLRDETGAIFID 65
           G+   AA G G+ V+LNVGGT F T+RQTL     SF S L  G  + + RDETGA  ID
Sbjct: 20  GAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLID 79

Query: 66  RDPAAFAPILNFLRTKELDL-RGVSINVLRHEAEFYGITPLVR 107
           RDP  F PILNFLR  +L L + ++   +  EAEFY I PL+R
Sbjct: 80  RDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIR 122


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 43/92 (46%), Positives = 55/92 (59%), Gaps = 2/92 (2%)

Query: 20  VQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLR 79
           + LNVGG  ++TS  TL   PDS   ++ SG++ T RD  G  FIDRD   F  ILNFLR
Sbjct: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64

Query: 80  TKELDLRG--VSINVLRHEAEFYGITPLVRRL 109
           T  LDL      + +LR EA+FY + PL+  L
Sbjct: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEAL 96


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 51/106 (48%), Positives = 58/106 (54%), Gaps = 14/106 (13%)

Query: 11  AAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLL---SGRISTLRDETGAIFIDRD 67
           A   G+   V+LNVGGT F T+RQTL   P SF   L       + + +DETGA  IDRD
Sbjct: 65  AGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRD 124

Query: 68  PAAFAPILNFLR------TKELDLRGVSINVLRHEAEFYGITPLVR 107
           P  F PILN+LR      TKEL   GV       EAEFY I  LVR
Sbjct: 125 PTYFGPILNYLRHGKLIITKELAEEGV-----LEEAEFYNIASLVR 165


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 43/92 (46%), Positives = 53/92 (57%), Gaps = 2/92 (2%)

Query: 20  VQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLR 79
           V LNVGG  ++TS  TL   PDS   ++  G   T RD  G  FIDRD   F  +LNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 80  TKE--LDLRGVSINVLRHEAEFYGITPLVRRL 109
           T E  L L     ++LR EA+FY I PL++ L
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 43/92 (46%), Positives = 53/92 (57%), Gaps = 2/92 (2%)

Query: 20  VQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLR 79
           V LNVGG  ++TS  TL   PDS   ++  G   T RD  G  FIDRD   F  +LNFLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 80  TKE--LDLRGVSINVLRHEAEFYGITPLVRRL 109
           T E  L L     ++LR EA+FY I PL++ L
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCL 105


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 46/117 (39%), Positives = 64/117 (54%), Gaps = 10/117 (8%)

Query: 1   MAGGHC-------GSFPAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGR-- 51
           + GG C       G+         + V+LNVGGT F T+RQTL   P SF   L      
Sbjct: 20  LGGGLCRRCSAGLGALAQRPGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPD 79

Query: 52  ISTLRDETGAIFIDRDPAAFAPILNFLRTKELDL-RGVSINVLRHEAEFYGITPLVR 107
           + + +DETGA  IDRDP  F P+LN+LR  +L + + ++   +  EAEFY IT L++
Sbjct: 80  LDSDKDETGAYLIDRDPTYFGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIK 136


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 36/92 (39%), Positives = 52/92 (56%), Gaps = 1/92 (1%)

Query: 18  EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNF 77
           E+V LN+GG  F+T   TL    D+  +++ SGR     D  G  FIDRD   F  +LNF
Sbjct: 51  EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNF 110

Query: 78  LRTKELDLRGVSINVLRHEAEFYGITPLVRRL 109
           LR+ +L  R   +  +  EA++Y I PL+ +L
Sbjct: 111 LRSGDLPPR-ERVRAVYKEAQYYAIGPLLEQL 141


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 38/93 (40%), Positives = 52/93 (55%), Gaps = 2/93 (2%)

Query: 19  IVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFL 78
           ++ LNVGG  + T +QTL   PD+F   +++G+I    D  G  FIDRD   F  +LNFL
Sbjct: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93

Query: 79  RTKELDL-RGVSIN-VLRHEAEFYGITPLVRRL 109
           R  EL L  G   N +L  EAEF+ +  L   +
Sbjct: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAEEV 126


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 4/92 (4%)

Query: 22  LNVGGTRFSTSRQTLM-WIPDSFFSSLLS--GRISTLRDETGAIFIDRDPAAFAPILNFL 78
           LNVGG  F+T+R TL+   PDS  + +    G     +D  GA  IDR P  F PILN+L
Sbjct: 93  LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPILNYL 152

Query: 79  RTKELDLR-GVSINVLRHEAEFYGITPLVRRL 109
           R  +L +  G+++  +  EA F+GI  L+  L
Sbjct: 153 RHGQLIVNDGINLLGVLEEARFFGIDSLIEHL 184


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 35/91 (38%), Positives = 49/91 (53%), Gaps = 2/91 (2%)

Query: 19  IVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFL 78
           +V+LNVGG   +T+  TL   P S  + + S       D  G  FIDR    F PIL++L
Sbjct: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93

Query: 79  RTKELDLRGVSINVLRHEAEFYGITPLVRRL 109
           RT ++  +   I  +  EA+FY I PLV+ L
Sbjct: 94  RTGQVPTQ--HIPEVYREAQFYEIKPLVKLL 122


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 2/93 (2%)

Query: 16  SGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPIL 75
           S E+V LNVGG  F+T   T+   P S  + +L GR    +   G IF+DRD   F+ IL
Sbjct: 3   SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62

Query: 76  NFLRTKELDLRGVSINVLR--HEAEFYGITPLV 106
           +FLRT +L L     + LR   EA FY +  LV
Sbjct: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLV 95


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 2/93 (2%)

Query: 16  SGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPIL 75
           S E+V LNVGG  F+T   T+   P S  + +L GR    +   G IF+DRD   F+ IL
Sbjct: 3   SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62

Query: 76  NFLRTKELDLRGVSINVLR--HEAEFYGITPLV 106
           +FLRT +L L     + LR   EA FY +  LV
Sbjct: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLV 95


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 11/111 (9%)

Query: 10  PAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLS---------GRISTLRDETG 60
           P A +   E+V+LNVGG  + T   TL+ +PDS  +S+ S          R    RD   
Sbjct: 36  PCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRA 95

Query: 61  AIFIDRDPAAFAPILNFLRTKELDL--RGVSINVLRHEAEFYGITPLVRRL 109
             FIDRD   F  +L++LR K+L L         L  EAE++ +T LV+ L
Sbjct: 96  RFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLL 146


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 42/127 (33%), Positives = 65/127 (51%), Gaps = 13/127 (10%)

Query: 4   GHCGSFPAAAAGSG------EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRIST--- 54
           G+C  +     GS       E+V+LNVGG  + T   TL+ IP S    + S +  T   
Sbjct: 5   GNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTAND 64

Query: 55  -LRDETGAIFIDRDPAAFAPILNFLRTKELDL--RGVSINVLRHEAEFYGITPLVRRLLL 111
             +D  G  FIDRD   F  IL++LR +++ L         L+ EAE++ +  LV +LL 
Sbjct: 65  LAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLV-KLLT 123

Query: 112 CEELERS 118
            +E+++S
Sbjct: 124 PDEIKQS 130


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 41/113 (36%), Positives = 61/113 (53%), Gaps = 6/113 (5%)

Query: 3   GGHCGSFPAAAAGS--GEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGR--ISTLRDE 58
           GG  GS  ++A      +IV+LNVGG  + T R T++ +PDS    + + +      RD 
Sbjct: 17  GGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDS 76

Query: 59  TGAIFIDRDPAAFAPILNFLRTKELDLRGV--SINVLRHEAEFYGITPLVRRL 109
            G  F+DRD   F  IL++LR  +L L       + L+ EAE++ +  LVRRL
Sbjct: 77  KGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129


>gi|27436984 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 1 [Homo sapiens]
          Length = 655

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 35/88 (39%), Positives = 45/88 (51%), Gaps = 3/88 (3%)

Query: 18  EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNF 77
           E++ LNV G RF T R TL   PD+   S  + +     ++T   F DRDP  F  +LNF
Sbjct: 40  ELIVLNVSGRRFQTWRTTLERYPDTLLGS--TEKEFFFNEDTKEYFFDRDPEVFRCVLNF 97

Query: 78  LRTKELDL-RGVSINVLRHEAEFYGITP 104
            RT +L   R   I+    E  FYGI P
Sbjct: 98  YRTGKLHYPRYECISAYDDELAFYGILP 125


>gi|27436986 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 2 [Homo sapiens]
          Length = 636

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 35/88 (39%), Positives = 45/88 (51%), Gaps = 3/88 (3%)

Query: 18  EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNF 77
           E++ LNV G RF T R TL   PD+   S  + +     ++T   F DRDP  F  +LNF
Sbjct: 40  ELIVLNVSGRRFQTWRTTLERYPDTLLGS--TEKEFFFNEDTKEYFFDRDPEVFRCVLNF 97

Query: 78  LRTKELDL-RGVSINVLRHEAEFYGITP 104
            RT +L   R   I+    E  FYGI P
Sbjct: 98  YRTGKLHYPRYECISAYDDELAFYGILP 125


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 10  PAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGA-IFIDRDP 68
           PA    S   V ++VGG  +++S  TL   PDS  S L +G    + D      FIDRD 
Sbjct: 48  PAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDG 107

Query: 69  AAFAPILNFLRTKELDLRG--VSINVLRHEAEFYGITPLVRRL 109
             F  +L+FLRT +L L       ++L  EA +Y + P+VR L
Sbjct: 108 EIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 10  PAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGA-IFIDRDP 68
           PA    S   V ++VGG  +++S  TL   PDS  S L +G    + D      FIDRD 
Sbjct: 48  PAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDG 107

Query: 69  AAFAPILNFLRTKELDLRG--VSINVLRHEAEFYGITPLVRRL 109
             F  +L+FLRT +L L       ++L  EA +Y + P+VR L
Sbjct: 108 EIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 38/103 (36%), Positives = 53/103 (51%), Gaps = 3/103 (2%)

Query: 10  PAAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGA-IFIDRDP 68
           PA    S   V ++VGG  +++S  TL   PDS  S L +G    + D      FIDRD 
Sbjct: 48  PAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDG 107

Query: 69  AAFAPILNFLRTKELDLRG--VSINVLRHEAEFYGITPLVRRL 109
             F  +L+FLRT +L L       ++L  EA +Y + P+VR L
Sbjct: 108 EIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 36/87 (41%), Positives = 44/87 (50%), Gaps = 3/87 (3%)

Query: 19  IVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFL 78
           ++ LNV GTRF T + TL   PD+   S  S R      ET   F DRDP  F  ILNF 
Sbjct: 42  LIVLNVSGTRFQTWQDTLERYPDTLLGS--SERDFFYHPETQQYFFDRDPDIFRHILNFY 99

Query: 79  RTKELDL-RGVSINVLRHEAEFYGITP 104
           RT +L   R   I+    E  F+G+ P
Sbjct: 100 RTGKLHYPRHECISAYDEELAFFGLIP 126


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 29/86 (33%), Positives = 51/86 (59%), Gaps = 1/86 (1%)

Query: 18  EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNF 77
           ++++LNVGG  ++  R++L    DS  +S+ SGR     DE+GA  IDRD   F  +L++
Sbjct: 12  DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71

Query: 78  LRTK-ELDLRGVSINVLRHEAEFYGI 102
           L  + ++     +   L+ EA+++GI
Sbjct: 72  LHGEVQIPTDEQTRIALQEEADYFGI 97


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 36/97 (37%), Positives = 46/97 (47%), Gaps = 4/97 (4%)

Query: 10  PAAAAGSG-EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDP 68
           P   A  G E++ +NV G RF T + TL   PD+   S  S +      ++G  F DRDP
Sbjct: 31  PGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGS--SEKEFFYDADSGEYFFDRDP 88

Query: 69  AAFAPILNFLRTKELDL-RGVSINVLRHEAEFYGITP 104
             F  +LNF RT  L   R   I     E  FYG+ P
Sbjct: 89  DMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVP 125


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 36/93 (38%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 16  SGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPIL 75
           S + V+LNVGG  + T+ QTL    D+   ++ SGR+  L D  G I IDR    F  IL
Sbjct: 30  SSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTIL 88

Query: 76  NFLRTKELDL--RGVSINVLRHEAEFYGITPLV 106
           N+LR   + L      I  L  EA++Y +  LV
Sbjct: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLV 121


>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
           [Homo sapiens]
          Length = 757

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 58/188 (30%), Positives = 75/188 (39%), Gaps = 22/188 (11%)

Query: 6   CGSFPAAAAG--------SGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRD 57
           C   PAAA G        SG+IV +NVGG R  T R TL  +P +  + L     +   D
Sbjct: 69  CPGLPAAAMGRHGGGGGDSGKIV-INVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFD 127

Query: 58  -ETGA--IFIDRDPAAFAPILNFLRTKELDL-RGVSINVLRHEAEFYGITPL-VRRLLLC 112
            + GA   F DR P  FA +LN+ RT +L     V   +   E  F+GI    V      
Sbjct: 128 YDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWM 187

Query: 113 EELERSSCGSVLFHGYLPPPGIPSRKINNTVRSADSRNGLNSTEGEARGNGTQPVLSGTG 172
              +       L     P P   +    N   +A + +G    E  A G G    L G G
Sbjct: 188 TYRQHRDAEEALDSFEAPDPAGAA----NAANAAGAHDGGLDDEAGAGGGG----LDGAG 239

Query: 173 EETVRLGF 180
            E  RL F
Sbjct: 240 GELKRLCF 247


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 36/89 (40%), Positives = 48/89 (53%), Gaps = 3/89 (3%)

Query: 20  VQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLR 79
           VQLNVGG+ + T+ + L    D+   ++ SGR+  L D+ G I IDR    F  ILN+LR
Sbjct: 30  VQLNVGGSLYYTTVRALTR-HDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88

Query: 80  --TKELDLRGVSINVLRHEAEFYGITPLV 106
             T  L      I  L  EA++Y I  LV
Sbjct: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLV 117


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 22  LNVGGTRFSTSRQTLM-WIPDSFFSSLLS--GRISTLRDETGAIFIDRDPAAFAPILNFL 78
           L+VGG  F+T+  TL+   PD   + +    G     +D  GA  ID+ P  F PILN+L
Sbjct: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152

Query: 79  RTKELDLR-GVSINVLRHEAEFYGITPLVRRL 109
           R  +L +  G+ +  +  EA F+GI  L+  L
Sbjct: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHL 184


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 22  LNVGGTRFSTSRQTLM-WIPDSFFSSLLS--GRISTLRDETGAIFIDRDPAAFAPILNFL 78
           L+VGG  F+T+  TL+   PD   + +    G     +D  GA  ID+ P  F PILN+L
Sbjct: 93  LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPILNYL 152

Query: 79  RTKELDLR-GVSINVLRHEAEFYGITPLVRRL 109
           R  +L +  G+ +  +  EA F+GI  L+  L
Sbjct: 153 RHGQLIVNDGIDLLGVLEEARFFGIDSLIEHL 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,791,582
Number of Sequences: 37866
Number of extensions: 1535076
Number of successful extensions: 6292
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 6163
Number of HSP's gapped (non-prelim): 172
length of query: 815
length of database: 18,247,518
effective HSP length: 111
effective length of query: 704
effective length of database: 14,044,392
effective search space: 9887251968
effective search space used: 9887251968
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.