BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|46049105 nebulin-related anchoring protein isoform S [Homo sapiens] (1730 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 3494 0.0 gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 2782 0.0 gi|115527120 nebulin [Homo sapiens] 1189 0.0 gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] 330 7e-90 gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 194 6e-49 gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] 159 3e-38 gi|47087157 nebulette non-muscle isoform [Homo sapiens] 125 5e-28 gi|5453710 LIM and SH3 protein 1 [Homo sapiens] 105 3e-22 gi|116517305 cysteine-rich protein 3 [Homo sapiens] 54 1e-06 gi|4503049 cysteine-rich protein 2 [Homo sapiens] 54 1e-06 gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens] 51 1e-05 gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens] 51 1e-05 gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] 50 1e-05 gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens] 50 2e-05 gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo s... 47 2e-04 gi|165905591 LIM domain and actin binding 1 isoform c [Homo sapi... 46 3e-04 gi|165905589 LIM domain and actin binding 1 isoform a [Homo sapi... 46 3e-04 gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens] 46 3e-04 gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Ho... 45 6e-04 gi|7662330 actin binding LIM protein family, member 3 [Homo sapi... 44 0.001 gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo... 44 0.002 gi|13386490 LIM domain containing 2 [Homo sapiens] 42 0.004 gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 42 0.005 gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 42 0.005 gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 42 0.005 gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 42 0.005 gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 42 0.005 gi|194272207 actin binding LIM protein family, member 2 isoform ... 42 0.005 gi|153792514 actin binding LIM protein family, member 2 isoform ... 42 0.005 gi|194272204 actin binding LIM protein family, member 2 isoform ... 42 0.005 >gi|46049105 nebulin-related anchoring protein isoform S [Homo sapiens] Length = 1730 Score = 3494 bits (9059), Expect = 0.0 Identities = 1730/1730 (100%), Positives = 1730/1730 (100%) Query: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK Sbjct: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 Query: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE Sbjct: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 Query: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR Sbjct: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180 Query: 181 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS Sbjct: 181 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240 Query: 241 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE Sbjct: 241 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300 Query: 301 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ Sbjct: 301 EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360 Query: 361 AQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRY 420 AQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRY Sbjct: 361 AQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRY 420 Query: 421 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 480 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR Sbjct: 421 EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 480 Query: 481 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 540 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK Sbjct: 481 QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 540 Query: 541 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS 600 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS Sbjct: 541 LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS 600 Query: 601 RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT 660 RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT Sbjct: 601 RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT 660 Query: 661 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ 720 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ Sbjct: 661 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ 720 Query: 721 RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 780 RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN Sbjct: 721 RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 780 Query: 781 LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 840 LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ Sbjct: 781 LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 840 Query: 841 GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 900 GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH Sbjct: 841 GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 900 Query: 901 HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK 960 HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK Sbjct: 901 HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK 960 Query: 961 YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN 1020 YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN Sbjct: 961 YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN 1020 Query: 1021 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR 1080 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR Sbjct: 1021 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR 1080 Query: 1081 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH 1140 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH Sbjct: 1081 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH 1140 Query: 1141 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS 1200 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS Sbjct: 1141 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS 1200 Query: 1201 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1260 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA Sbjct: 1201 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1260 Query: 1261 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1320 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI Sbjct: 1261 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1320 Query: 1321 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1380 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD Sbjct: 1321 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1380 Query: 1381 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1440 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE Sbjct: 1381 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1440 Query: 1441 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1500 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF Sbjct: 1441 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1500 Query: 1501 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG Sbjct: 1501 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560 Query: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS Sbjct: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620 Query: 1621 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1680 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR Sbjct: 1621 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1680 Query: 1681 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL 1730 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL Sbjct: 1681 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL 1730 >gi|46049092 nebulin-related anchoring protein isoform C [Homo sapiens] Length = 1695 Score = 2782 bits (7212), Expect = 0.0 Identities = 1416/1586 (89%), Positives = 1458/1586 (91%), Gaps = 37/1586 (2%) Query: 181 AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240 A LA++ Y G+ E + + PE++R A+ YTEDYEQ RGKGS Sbjct: 111 APNRQPLANERAYWTGYGEGNAWCPGALPDPEIVRM-VEARKSLGEEYTEDYEQPRGKGS 169 Query: 241 FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECAD-QYGQGYP 299 FPAMITPAYQ AK+AN+LAS V Y + + + + + E + ++ A Q Y Sbjct: 170 FPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYT 229 Query: 300 EEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNK-MKGAA------------- 345 E+YE+ RGKGSFPAMITPAYQ AK+A+ELASD++Y Q + K M+G A Sbjct: 230 EDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRE 289 Query: 346 -----------HYH------SLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRG----HS 384 Y S PA + A+ ++L S+++Y++D +G HS Sbjct: 290 CADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHS 349 Query: 385 INYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAY 444 + + + ++K S+NKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAY Sbjct: 350 LPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAY 409 Query: 445 KADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINA 504 KADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINA Sbjct: 410 KADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINA 469 Query: 505 QQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLD 564 QQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLD Sbjct: 470 QQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLD 529 Query: 565 AMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEES 624 AMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEES Sbjct: 530 AMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEES 589 Query: 625 KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYK 684 KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYK Sbjct: 590 KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYK 649 Query: 685 ADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQE 744 ADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQE Sbjct: 650 ADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQE 709 Query: 745 LQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS 804 LQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS Sbjct: 710 LQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS 769 Query: 805 LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF 864 LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF Sbjct: 770 LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF 829 Query: 865 EDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDN 924 EDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDN Sbjct: 830 EDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDN 889 Query: 925 QYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARI 984 QYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARI Sbjct: 890 QYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARI 949 Query: 985 SYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR 1044 SYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR Sbjct: 950 SYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR 1009 Query: 1045 LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK 1104 LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK Sbjct: 1010 LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK 1069 Query: 1105 KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQ 1164 KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQ Sbjct: 1070 KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQ 1129 Query: 1165 SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLH 1224 SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLH Sbjct: 1130 SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLH 1189 Query: 1225 AKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGY 1284 AKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGY Sbjct: 1190 AKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGY 1249 Query: 1285 KLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSEL 1344 KLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSEL Sbjct: 1250 KLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSEL 1309 Query: 1345 QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH 1404 QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH Sbjct: 1310 QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH 1369 Query: 1405 ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD 1464 ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD Sbjct: 1370 ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD 1429 Query: 1465 LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA 1524 LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA Sbjct: 1430 LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA 1489 Query: 1525 GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1584 GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ Sbjct: 1490 GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1549 Query: 1585 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQ 1644 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQ Sbjct: 1550 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQ 1609 Query: 1645 KAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEA 1704 KAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEA Sbjct: 1610 KAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEA 1669 Query: 1705 GDHQSGEVNPDATEILHVKKKKALLL 1730 GDHQSGEVNPDATEILHVKKKKALLL Sbjct: 1670 GDHQSGEVNPDATEILHVKKKKALLL 1695 >gi|115527120 nebulin [Homo sapiens] Length = 6669 Score = 1189 bits (3075), Expect = 0.0 Identities = 619/1546 (40%), Positives = 974/1546 (63%), Gaps = 55/1546 (3%) Query: 155 EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214 + Y +YE+ RGKG FP IT Y+ KK +Q YK D+ ++F+ V D+P LL Sbjct: 456 KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHT-YKVHPDK--TKFTQVTDSPVLL 512 Query: 215 RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274 +++ ++ SD+ Y +E ++ K P TPA+ K SD Y Q ++K Sbjct: 513 QAQVNSKQLSDLNYKAKHESEKFKCHIPPD-TPAFIQHKVNAYNLSDNLYKQDWEKSKAK 571 Query: 275 MAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKY 334 + A +L AK + SD+ Y Sbjct: 572 KFDIKVDAIPLLA----------------------------------AKANTKNTSDVMY 597 Query: 335 RQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFR 394 ++D+ K KG L D+ + + V K S+ YK++ E ++ S+NYCETP+++ Sbjct: 598 KKDYEKNKGKM-IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656 Query: 395 NVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVD 454 +++ F S+ +YK+ Y + G Y G D H MKV + S+ +YKA+Y+ D Sbjct: 657 LDTQLKNF-SEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGK 715 Query: 455 YNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRA 514 +P T+T Y+ KL KD Y+ DK K+++VTD+P ++QA++N +QLS +NY+A Sbjct: 716 CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKA 775 Query: 515 DYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKAS 574 +E K +P D PQ ++ + NA S+ YK+ WEK+K K F++K+DA+ LLAAKA+ Sbjct: 776 KHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKAN 835 Query: 575 GELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHL 630 + S++ YK++YEK+KGK +G D ++LHSL+ AK S+ EY+K +E+SKT + Sbjct: 836 TKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTA 895 Query: 631 PMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AW 689 P+DM+ + AKK+Q +ASD+DY+ LH Y+ P+ + AKKAY LQS+++YKAD +W Sbjct: 896 PLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSW 955 Query: 690 MKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGV 749 MKG GW+ GSL +E+AK+A +++EK YRQ D LKFTS+ D+ +K +Q +S + Sbjct: 956 MKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015 Query: 750 AYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLA 809 AYKA E+ +H+Y + D P F+QA+ NA N+SE +YK+ ++ KG++LR D++ A Sbjct: 1016 AYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRA 1075 Query: 810 AKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKS 869 AKA R AS+V+YK+DYE+++GK++G + +Q D ++ H + ++K+QS+ EYKK +E TKS Sbjct: 1076 AKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKS 1135 Query: 870 QCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRAD 929 + + DM ++V A+KAQ + ++V YK + HH+T LP M +E +K +QSDN Y+ D Sbjct: 1136 KYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKED 1195 Query: 930 VK-WMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQ 988 WMKG+GW+ GSL+VE+ KKAG+ ++EKKYRQHPD LKFTSI D+P MVQA+ + Q Sbjct: 1196 YNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQ 1255 Query: 989 AVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDAL 1048 D LY+ +GE++KH YT + DLP+ L AK NA NIS+ YK W L G + DA+ Sbjct: 1256 VSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAI 1315 Query: 1049 PFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFE 1108 P AAKAS I SDYKYKEA+EK KG+ +G RSL+DD L H + LQSD YKK +E Sbjct: 1316 PITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYE 1375 Query: 1109 HSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL 1168 ++K +H P DM ++ AK AQ +A+N +YK PL YT L + + L + +++QS+N+ Sbjct: 1376 NTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNV 1435 Query: 1169 YRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKF 1227 Y+ + N F++G+ + G+LE+E KKA + ++E KYRQHP + K+T+V D+ ++ A+ Sbjct: 1436 YKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQH 1495 Query: 1228 SNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLT 1287 + + ++ YK GE +H+YT+ LP+FI+AK NA N+SDA YK W+ A+GY L Sbjct: 1496 NTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLR 1555 Query: 1288 IEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1347 +A+P AA++S +IASD Y+ + K +GK +G S++DDP++ H + ++QS+ +Y+ Sbjct: 1556 PDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYK 1615 Query: 1348 RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQ 1407 +G +S+ ++H P+DMV + AK +Q +A++ +YR YH +T LP+ L + ++ A +Q Sbjct: 1616 KGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQ 1675 Query: 1408 SELRYKSDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLV 1466 S+ YKSD MKGIGW+ + S ++E AKKAGE++SE KYR+ P+ +KFT +D+ + Sbjct: 1676 SDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQA 1735 Query: 1467 HAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTR 1523 K++ ++ ++R+Y + D ++H ++PD PD +R+N + +SDK+Y+ WE+ + Sbjct: 1736 LNKSNKLNMDKRLYTEKWNKDKTTIH---VMPDTPDILLSRVNQITMSDKLYKAGWEEEK 1792 Query: 1524 AGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRL 1583 YD R DAI + ARASR+IASD++YK+A+ + +G IG+RS++DDP++ HF+ V ++ Sbjct: 1793 KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKM 1852 Query: 1584 QSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHA 1643 QSD EYKK + KS++ FH+ D ++ AK+SQ++A++ +YR + P+ + A Sbjct: 1853 QSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELA 1912 Query: 1644 QKAHQLQSDVKYKSD-LNLTRGVGWTPPGSYKVEMARRAAELANAR 1688 + Q+QSD +YK+D + +G+GW P GS + E ++A E+ + + Sbjct: 1913 KNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEK 1958 Score = 1135 bits (2936), Expect = 0.0 Identities = 619/1646 (37%), Positives = 983/1646 (59%), Gaps = 57/1646 (3%) Query: 60 KNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLAN 119 K + S TP ++ + +S + + DG+ K++ H D K+KD E A + Sbjct: 109 KGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVS 168 Query: 120 ERAY---WTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMIT 175 + Y W + P A PE+V+ V+ ++ YTED+E + +P + Sbjct: 169 KVLYKQNWEDTKDKYLLPPDA---PELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDS 224 Query: 176 PAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQ 235 P +R +A + S V YK+G E+ ++F+ + D P++ +K S +Y EDYE + Sbjct: 225 PELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENK 284 Query: 236 -RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294 +GK S TP +++ A + A+ I TR+ Sbjct: 285 IKGKWS----ETPCFEV------------------------ANARMNADNISTRK----- 311 Query: 295 GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQD 354 Y E++E + + F TP Y+ KKA AS +KY++D+ K KG A Y+ LPA + Sbjct: 312 ---YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASE 368 Query: 355 NLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQN 414 N L+Q ++ +S+ YK++ E ++ SINYCETP+F+ + + F+SD KYK++Y Sbjct: 369 NPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLK 428 Query: 415 HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 474 + G Y G D H MKV + S+ YKA+Y+ D +P T+T Y+ KL Sbjct: 429 DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488 Query: 475 KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 534 KD Y+ DK K++ VTD+P ++QA++N++QLS +NY+A +E K +P D P ++ Sbjct: 489 KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548 Query: 535 AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 594 K NA S+ YK+ WEK+K K F++K+DA+ LLAAKA+ + S++ YK++YEK KGK Sbjct: 549 HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608 Query: 595 MGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR----FHLPMDMVNIRHAKKAQTL 646 +G D ++LHSL++AK S+ YK+ +E++K + P ++ + ++ Sbjct: 609 IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEAR 668 Query: 647 ASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQA 706 DL + L Y ED K S+ YKA+ KG + + +A Sbjct: 669 YKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEA 728 Query: 707 KKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 766 K + Y+ D+ KFT+VTDS + A+ + + S + YKA +E + I Sbjct: 729 IKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPA 788 Query: 767 DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 826 D P F+Q R NA NLS+ +YK WE KAK F++++D++ LAAKA S+V YK+DY Sbjct: 789 DAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDY 848 Query: 827 ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 886 E+S+GK+IGA + D +M HSL+ +K QS+ EY+K +E +K+ LDM+ + A+K+ Sbjct: 849 EKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKS 908 Query: 887 QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLN 945 Q +A+DV YK H ++ P + V+ AKKAY LQSD +Y+AD WMKG GWV GSL Sbjct: 909 QAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE 968 Query: 946 VEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHY 1005 +E+AK+A ++++EKKYRQHPD LKFTSI+D P VQ++I+ Q D Y+ +GE I H Y Sbjct: 969 MEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKY 1028 Query: 1006 TPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKY 1065 DLP+ + AK+NA NISE YK L GY LR DA+P +AAKA+ + SD +Y Sbjct: 1029 NLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY 1088 Query: 1066 KEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVH 1125 K+ +EK KG+M+G +SL+DD L H + +QSD YKK +E +K++++ P DM +V Sbjct: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA 1148 Query: 1126 AKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIP 1184 AKKAQ + SN +YKH L YT L + + L +K ++QS+N+Y+ D N+M+G+ + Sbjct: 1149 AKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPI 1208 Query: 1185 GTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDA 1244 G+L++E KKA + ++E KYRQHP + K+T++ D+P ++ AK + + ++ LYKA GED Sbjct: 1209 GSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDV 1268 Query: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304 +H+YTM+ LP+F++AK NA N+SD YK W +L A+G + +A+P AA+AS +IAS Sbjct: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328 Query: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMV 1364 D+ Y+ + K +GK +G +S++DDP++ H + +LQS+ +Y++ +++ +H P DMV Sbjct: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388 Query: 1365 HLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIG 1423 + AK AQ +A++ +Y+ H +T LP+ + + + + +QS+ YK + +KGIG Sbjct: 1389 SITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIG 1448 Query: 1424 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSG 1483 W+ + S ++E KKAG+ ++E KYR+ PD++KFT+V DS +V A+++ ++ Y+ Sbjct: 1449 WIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVE 1508 Query: 1484 DAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASR 1543 + H+YT+ P+ P F +A++NAL++SD Y+ W++T A YD R DAIP A++SR Sbjct: 1509 GEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSR 1568 Query: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603 IASD +YKEA+ + +G Q+G+ S+ DDP++ H++NV ++QSD EYKK + S++++H+ Sbjct: 1569 NIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTP 1628 Query: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-NLT 1662 D + AK+SQ++A++ +YRQ T P+ L + H++ A Q+QSD YKSD N Sbjct: 1629 LDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWM 1688 Query: 1663 RGVGWTPPGSYKVEMARRAAELANAR 1688 +G+GW P S +VE A++A E+ + + Sbjct: 1689 KGIGWVPIESLEVEKAKKAGEILSEK 1714 Score = 1052 bits (2721), Expect = 0.0 Identities = 592/1572 (37%), Positives = 930/1572 (59%), Gaps = 75/1572 (4%) Query: 136 GALPDPEIVRMVE-ARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYK 194 G++ DP ++ A ++ + Y +YE+ +GK FP IT Y+ KK +Q YK Sbjct: 683 GSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHT-YK 741 Query: 195 RGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKR 254 D+ ++F+ V D+P LL+++ + SD+ Y +E ++ K PA Q Sbjct: 742 VHPDK--TKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVN 799 Query: 255 ANELASDVRYHQQYQK------EMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK 308 A L+ +V Y Q ++K +++ A P + A+ T+ +D Y ++YE+ +GK Sbjct: 800 AYNLSDNV-YKQDWEKSKAKKFDIKVDAIPLLAAKA-NTKNTSDVM---YKKDYEKSKGK 854 Query: 309 --GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNK 366 G+ P ++ K + SD +YR+D+ K K ++ P D L + QA+ Sbjct: 855 MIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSK---TIYTAPL-DMLQVTQAKKSQA 910 Query: 367 LVSEVEYKKDLESSRGHSINYCETPQFRNVSKISK---FTSDNKYKENYQNHMRGRYEGV 423 + S+V+YK L S Y P NV K SD +YK +Y + M+G Sbjct: 911 IASDVDYKHILHS-------YSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKG----- 958 Query: 424 GMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSI 483 + GSL A +A DI L + YRQ Sbjct: 959 ------CGWVPFGSLEMEKAKRAS---DI---------------------LNEKKYRQHP 988 Query: 484 DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFS 543 D LK++S+ D P VQ+KIN Q S + Y+A E+ Y LP D+PQ ++AK NA S Sbjct: 989 DTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNIS 1048 Query: 544 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG----TAD 599 E YK + KG++++ DA+ + AAKA+ + AS+++YK++YEK KGK +G D Sbjct: 1049 ENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDD 1108 Query: 600 SRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEY 659 +L+H + +AK+ S+ EYKK +E++K++++ P DM N+ AKKAQ + S+++Y+ LH Y Sbjct: 1109 PKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHY 1168 Query: 660 TVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGWLTEGSLNLEQAKKAGQLVSEKNY 718 T LP+ M + +K +QS+ YK D WMKG+GW+ GSL++E+ KKAG ++EK Y Sbjct: 1169 TYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKY 1228 Query: 719 RQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANA 778 RQ D LKFTS+ DS M AK++ + S + YKA E H+YT+S D P FLQA+ NA Sbjct: 1229 RQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNA 1288 Query: 779 ANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKD 838 N+S+ YK W + AKG + D++ AAKA R++AS+ KYKE YE+S+GK +G + Sbjct: 1289 YNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRS 1348 Query: 839 VQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTA 898 +Q D ++ H + ++KLQS+ EYKK +E+TK+ H DMV + A+ AQ +AT+V YK Sbjct: 1349 LQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQP 1408 Query: 899 EHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLNVEQAKKAGELIS 957 HH+T LP M +E + +QSDN Y+ + ++KG+GW+ GSL VE+ KKAG+ ++ Sbjct: 1409 LHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALN 1468 Query: 958 EKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLA 1017 E+KYRQHPD +KFTS+ D+ MV A+ + Q D Y+ +GE +KH YT +LP+ + A Sbjct: 1469 ERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQA 1528 Query: 1018 KLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQML 1077 K+NA+N+S+ YK W K GY LR DA+P AAK+S I SD KYKEA+EK KG+ + Sbjct: 1529 KVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQV 1588 Query: 1078 GSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQD 1137 G SL+DD L H + +QSD YKKG+E SK ++H PLDM ++ AKK+Q +A+N + Sbjct: 1589 GFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVATNAN 1648 Query: 1138 YKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIPGTLEIEGRKKAS 1196 Y+ YT L + L + ++ A ++QS+NLY+SD N+M+G+ V +LE+E KKA Sbjct: 1649 YRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAG 1708 Query: 1197 ELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPE 1256 E++SE KYRQHP K+T DT K + ++RLY + + P+ Sbjct: 1709 EILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPD 1768 Query: 1257 FIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKER 1316 + ++ N +SD YK W + +GY L +A+ +AARAS DIASD+ Y+ + + + Sbjct: 1769 ILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAK 1828 Query: 1317 GKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALA 1376 GK IG +S+ DDP++ H ++ ++QS+ +Y++G S+ FH P+DM+ +V AK +Q +A Sbjct: 1829 GKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVA 1888 Query: 1377 SDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQMESA 1435 ++ +YR H + LP+ + AK +QS+ +YK+D MKGIGWL L S + E Sbjct: 1889 TNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKN 1948 Query: 1436 KKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIP 1495 KKA E+ISE KYR+ PD++K++T++DS ++V A+N+ NE +Y+ + ++P Sbjct: 1949 KKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP 2008 Query: 1496 DHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAF 1555 D P A+ NA+++SDK+Y+ S E+++ YD R DAIP + A+ASR+IASD++YK + Sbjct: 2009 DIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNY 2068 Query: 1556 LRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRS 1615 + +G +G+RS++DDP++ H + V ++QSD EYKK++ +++ +H+ D + AK + Sbjct: 2069 EKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDA 2128 Query: 1616 QQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLN-LTRGVGWTPPGSYK 1674 Q ++ +Y+ + + P+ + + + +++QSD +YK D N +G+GW+P GS + Sbjct: 2129 QANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLE 2188 Query: 1675 VEMARRAAELAN 1686 VE A++A E A+ Sbjct: 2189 VEKAKKATEYAS 2200 Score = 1038 bits (2683), Expect = 0.0 Identities = 592/1602 (36%), Positives = 935/1602 (58%), Gaps = 82/1602 (5%) Query: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 DP++V + K + EY +DYE+ + K + P + AKKA + S V YK Sbjct: 1108 DPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA-AKKAQDVVSNVNYKHS-- 1164 Query: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ-QRGKGSFPAMITPAYQIAKRANE 257 + ++ + D +L SK Q+QSD Y EDY +G G P ++ K + Sbjct: 1165 --LHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDA 1222 Query: 258 L-ASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMIT 316 L R H K + P + T++ +D Y + E+ + K + + Sbjct: 1223 LNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL---YKAKGEDVKHKYTMSPDL- 1278 Query: 317 PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA------QSVNKLVSE 370 P + AK SD+ Y++D +H L A+ N VL A ++ + S+ Sbjct: 1279 PQFLQAKCNAYNISDVCYKRD---------WHDLIAKGNNVLGDAIPITAAKASRNIASD 1329 Query: 371 VEYKKDLESSRGHSINYC---ETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427 +YK+ E S+G + + + P+ + ++K SD +YK+NY+N + Y G D Sbjct: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYEN-TKTSYHTPG-DM 1387 Query: 428 RTLHAMKVGSLASNVAYKADYKHDIVDYNY-PATLT-----------------PSYQTAM 469 ++ A K +A +VA +YK + Y Y P ++ Y + + Sbjct: 1388 VSITAAK---MAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFL 1444 Query: 470 KLV------------------PLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 511 K + L + YRQ D +K++SV D+ +V A+ N +QLS +N Sbjct: 1445 KGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLN 1504 Query: 512 YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571 Y+ + EK K YT+ ++PQ ++AK NA S+ YK W+KT KG++++ DA+ ++AA Sbjct: 1505 YKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAA 1564 Query: 572 KASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR 627 K+S +AS+ KYKE YEK KGK +G D +L+H + +AK+ S+ EYKKG+E SKT+ Sbjct: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK 1624 Query: 628 FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 687 +H P+DMV++ AKK+Q +A++ +YR+ H YT+LP+ + + ++ A +QS+ YK+D Sbjct: 1625 YHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDF 1684 Query: 688 A-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQ 746 WMKG+GW+ SL +E+AKKAG+++SEK YRQ ++LKFT D+ + K ++ Sbjct: 1685 TNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNM 1744 Query: 747 SGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLT 806 Y + + D P L +R N +S+KLYK+ WE +K KG++LR D++ Sbjct: 1745 DKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIA 1804 Query: 807 FLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED 866 AA+A RD+AS+ KYK+ YE+++GK IG + ++ D ++ H +Q++K+QS+ EYKKG+E Sbjct: 1805 IKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEK 1864 Query: 867 TKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQY 926 +K+ H +DM+ +V A+K+Q +AT+ Y+ H + LP M E AK +QSDNQY Sbjct: 1865 SKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQY 1924 Query: 927 RAD-VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARIS 985 +AD +MKG+GW+ GSL E+ KKA E+ISEKKYRQHPD LK++++ D+ MV A+ + Sbjct: 1925 KADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNN 1984 Query: 986 YTQAVDRLYRE--QGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKL 1043 + LY++ + + K H P D+P+++LAK NA+N+S+ YK S + + GY L Sbjct: 1985 AKIMNEHLYKQAWEADKTKVHIMP--DIPQIILAKANAINMSDKLYKLSLEESKKKGYDL 2042 Query: 1044 RLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNY 1103 R DA+P +AAKAS +I SDYKYK +EK KG+M+G RSLEDD L HS+ +QSD Y Sbjct: 2043 RPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREY 2102 Query: 1104 KKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKL 1163 KK +E++K +H P DM ++ AK AQ +N +YKH + +Y L + + + + +++ Sbjct: 2103 KKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRI 2162 Query: 1164 QSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNL 1222 QS+N Y+ D N + +G+ G+LE+E KKA+E S+ KYRQHP +F++ +TD+ ++ Sbjct: 2163 QSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDM 2222 Query: 1223 LHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQ 1282 + AK + N+ LY + + + P+ ++AK N S YK W + Sbjct: 2223 VLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKK 2282 Query: 1283 GYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQS 1342 GY L ++A+ Q A+AS DIASD+ Y+ + K+ G +G +S++DDP++ + ++QS Sbjct: 2283 GYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQS 2342 Query: 1343 ELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKK 1402 E +Y++ + +F P+DM+ +V AK Q L SD DY+ H++T LP+ + AKK Sbjct: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKK 2402 Query: 1403 AHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDS 1462 + LQSE YKSDL ++GIGW L S + E K+A E+ISE KYR+ PD KFT++ D+ Sbjct: 2403 VYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDA 2462 Query: 1463 PDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQT 1522 D+V AK + + ++R+YR + + ++PD PD A+ N ++ SDK+YR +E+ Sbjct: 2463 MDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEEL 2522 Query: 1523 RAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGR 1582 + YD +DAIP + A+ASREIAS+++YKE F + G IG R+++DDP+M ++V + Sbjct: 2523 KRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAK 2582 Query: 1583 LQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRH 1642 +QSD EYKKDF K +++F S D G++ AK+ Q L SDV Y+ L Q TC P+Q + H Sbjct: 2583 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIH 2642 Query: 1643 AQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684 A++A+ LQSD YKSDL +G+GW GS + E +RA ++ Sbjct: 2643 ARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQI 2684 Score = 1022 bits (2642), Expect = 0.0 Identities = 603/1626 (37%), Positives = 937/1626 (57%), Gaps = 61/1626 (3%) Query: 109 EGAPNRQPLANERAYWTGYGEGNAWCPGALP---DPEIVRMVEARKSLGE-EYTEDYEQP 164 + A + +A++ Y Y +G G DP++V ++ K + EY ++YE Sbjct: 2050 KAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENT 2109 Query: 165 RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224 + PA + + AK A + YK I ++ + D + ++ ++QS Sbjct: 2110 KTSYHTPADML-SVTAAKDAQANITNTNYKH----LIHKYILLPDAMNIELTRNMNRIQS 2164 Query: 225 DVRYTEDY-EQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQ----KEMRGMAGPA 279 D Y +DY E +G G PA + AK+A E ASD +Y Q K++ Sbjct: 2165 DNEYKQDYNEWYKGLGWSPAGSLEVEK-AKKATEYASDQKYRQHPSNFQFKKLTDSMDMV 2223 Query: 280 IGAEGILT-----------------------------RECADQYGQG-YPEEYEEHRGKG 309 + + T ++ Y Q Y +EE KG Sbjct: 2224 LAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKG 2283 Query: 310 SFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369 + + Q AK + ++ASD KY+Q + K G H QD+ L + +V K+ S Sbjct: 2284 YDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGH-HVGFRSLQDDPKLVLSMNVAKMQS 2342 Query: 370 EVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRT 429 E EYKKD E + + + K + SD YK NY + ++ + Sbjct: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYK-NYLH----QWTCLPDQNDV 2397 Query: 430 LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489 + A KV L S YK+D + P + + + + YRQ D+ K++ Sbjct: 2398 VQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFT 2457 Query: 490 SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549 S+ D IV AK NA+ S YR ++K+K + D P +V AK N S+ Y+ Sbjct: 2458 SIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRM 2517 Query: 550 GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605 G+E+ K KG+++ +DA+ + AAKAS E+AS KYKE + K G +G D +++ S Sbjct: 2518 GYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWS 2577 Query: 606 LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665 + +AK+ S+ EYKK FE+ KT+F P+DM+ + AKK QTL SD+DY+ LH++T LP+ Sbjct: 2578 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2637 Query: 666 MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725 A++AY LQS+ YK+DL W+KG+GW+T GSL E+ K+A Q++S+ YRQ D+ Sbjct: 2638 SDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQF 2697 Query: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785 KF+S+ DS M AK + + Y ++ I D P L A+ N N SEKL Sbjct: 2698 KFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKL 2757 Query: 786 YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845 YK E K KG+++R+D++ AAKA RD+ASE KYKE Y + G IGA+ ++ D +M Sbjct: 2758 YKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKM 2817 Query: 846 SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905 S+ ++K+QS+ EYKK FE K++ +DM+ +V A+K Q L +DV YK H +T L Sbjct: 2818 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCL 2877 Query: 906 PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965 P V A++AY LQSDN Y++D++WM+G+GWV+ GSL+VE+ K+A E++S+K YRQ P Sbjct: 2878 PDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPP 2937 Query: 966 DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025 D KFTS+ D+ E V A+ + RLY E + K D PE++LA+ N +N S Sbjct: 2938 DRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYS 2997 Query: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085 ET YK + + + GY LR DA+P AAKAS ++ISDYKYK+ + K G +G+R++EDD Sbjct: 2998 ETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057 Query: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145 + S++ +QSD YKK FE K +F P+DM +V AKK QTL S+ DYK+ L ++ Sbjct: 3058 PKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEW 3117 Query: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205 T L + + A++A+ LQS+N+Y+SDL ++RG+ V G++++ K+A+E++S++ YR Sbjct: 3118 TCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYR 3177 Query: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265 Q P K+T+VTD+ + AK + N+RLY A + + + + PE + A+ N Sbjct: 3178 QPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKI 3237 Query: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325 N S++ Y+++ + +GY L +A+P AA+AS DIASD+ Y+ + K+ G IG ++V Sbjct: 3238 NYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAV 3297 Query: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385 DDP+I + ++QS+ +Y++ + ++ P+DM+ +V AK Q L SD DY+ Sbjct: 3298 HDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPL 3357 Query: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445 H++ LP+ + A+KA+ LQS+ YKSDL MKGIGW+ + S ++ AK+AGEL+S+T Sbjct: 3358 HEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDT 3417 Query: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502 YR++P+++KFT++ D+P+ V AKN+ ++ N+R+Y D +++H ++PD P+ Sbjct: 3418 IYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH---VMPDTPEIML 3474 Query: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562 A+LN ++ SDK+Y+ + E+++ YD RLDAIP Q A+ASR+IASD++YKE + + G Sbjct: 3475 AKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHH 3534 Query: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622 IG R++ DDP+M ++V ++QSD EYKK+F K +++F S D G++ AK+ Q L SD+ Sbjct: 3535 IGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDI 3594 Query: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682 Y+ PL + TC P+Q + A+KA+ LQSD YKSDL RG+GW P GS +VE +RA Sbjct: 3595 DYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAG 3654 Query: 1683 ELANAR 1688 E+ + R Sbjct: 3655 EILSDR 3660 Score = 1021 bits (2639), Expect = 0.0 Identities = 589/1588 (37%), Positives = 926/1588 (58%), Gaps = 59/1588 (3%) Query: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 DP++V + K E EY +D+E+ + K S P + AKK +L S V+YK Sbjct: 2328 DPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKN--- 2383 Query: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258 + +++ + D +++++K +LQS+ Y D E RG G P A + KRA+E+ Sbjct: 2384 -YLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEK-NKRASEI 2441 Query: 259 ASDVRYHQQYQKEMRGMAGPAI----------GAEGILTRECADQ--------------- 293 S+ +Y Q + A+ L RE D+ Sbjct: 2442 ISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIV 2501 Query: 294 ---------YGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344 + Y YEE + KG + + AK + E+AS+ KY++ F K G Sbjct: 2502 LAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGH 2561 Query: 345 AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404 H + +D+ + + V K+ S+ EYKKD E + + + K S Sbjct: 2562 -HIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2620 Query: 405 DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH-DIVDYNYPATLTP 463 D YK NY + ++ + +HA + L S+ YK+D + + + +L Sbjct: 2621 DVDYK-NYLH----QWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLED 2675 Query: 464 SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNY 523 + L D YRQ D+ K+SS+ D+ +V AK NA ++H Y ++K+K Sbjct: 2676 EKNKRATQI-LSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTV 2734 Query: 524 TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKY 583 + D P+++ AK N +SE YK G E+ K KG++M++DA+ + AAKAS ++AS KY Sbjct: 2735 HIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKY 2794 Query: 584 KEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRH 639 KE Y K G +G D +++ S+ +AK+ S+ EYKK FE+ KT+F P+DM+ + Sbjct: 2795 KEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL 2854 Query: 640 AKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEG 699 AKK QTL SD+DY+ LH++T LP+ A++AY LQS+ YK+DL WM+G+GW++ G Sbjct: 2855 AKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIG 2914 Query: 700 SLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 759 SL++E+ K+A +++S+K YRQ D KFTSVTDS + AK + + Y ++ Sbjct: 2915 SLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 2974 Query: 760 HQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASE 819 Q I D P + AR N N SE LYK + E K KG++LR D++ +AAKA RD+ S+ Sbjct: 2975 TQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISD 3034 Query: 820 VKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVH 879 KYK+ Y + G IGA++++ D +M S+ ++K+QS+ EYKK FE K++ +DM+ Sbjct: 3035 YKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 3094 Query: 880 LVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWV 939 +V A+K Q L +DV YK H +T LP V A++AY LQSDN Y++D++W++G+GWV Sbjct: 3095 VVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWV 3154 Query: 940 ATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGE 999 GS++V + K+A E++S+ YRQ PD LKFTS+ D+ E V A+ + RLY E + Sbjct: 3155 PIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWD 3214 Query: 1000 NIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEI 1059 K D PE++LA+ N +N SE+ Y+++ + + GY LR DA+P AAKAS +I Sbjct: 3215 KDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDI 3274 Query: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119 SDYKYKEA+ K G +G+R++ DD + S++ +QSD YKK FE K ++ P+D Sbjct: 3275 ASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVD 3334 Query: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179 M +V AKK QTL S+ DYKHPL ++ L + + A+KA+ LQS+NLY+SDL +M+G+ Sbjct: 3335 MLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGI 3394 Query: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKA 1239 V +LE+ K+A EL+S++ YRQ P + K+T++TDTP + AK + N+RLY Sbjct: 3395 GWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTE 3454 Query: 1240 AGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARAS 1299 A ++ + + PE + AK N N SD YK + + +GY L ++A+P QAA+AS Sbjct: 3455 AWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKAS 3514 Query: 1300 GDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHL 1359 DIASD+ Y+ + K+ G IG ++++DDP++ + ++QS+ +Y++ + +F Sbjct: 3515 RDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSS 3574 Query: 1360 PMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGM 1419 P+DM+ +V AK Q L SD DY+ H++T LP+ + A+KA+ LQS+ YKSDL + Sbjct: 3575 PVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWL 3634 Query: 1420 KGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERM 1479 +GIGW+ + S ++E K+AGE++S+ KYR+ D +KFT + D+P++V AKN+ + ++ + Sbjct: 3635 RGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHL 3694 Query: 1480 YR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPF 1536 Y D S+H ++PD PD A+ N+ ++S K+Y W++++ YD R DAI Sbjct: 3695 YTEAWDADKTSIH---VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISI 3751 Query: 1537 QTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKS 1596 ++A+ASR+IASD++YKEA+ + +G IG +S++DDP++ ++ G++QS+ EYKK+F K Sbjct: 3752 KSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKW 3811 Query: 1597 RSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYK 1656 +++F S D +L AK+ Q L +D+ YR L + TC P+Q + A+KA+ LQSD YK Sbjct: 3812 KTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYK 3871 Query: 1657 SDLNLTRGVGWTPPGSYKVEMARRAAEL 1684 +DL RG+GW P GS +V + A + Sbjct: 3872 ADLEWLRGIGWMPQGSPEVLRVKNAQNI 3899 Score = 979 bits (2531), Expect = 0.0 Identities = 582/1622 (35%), Positives = 924/1622 (56%), Gaps = 63/1622 (3%) Query: 109 EGAPNRQPLANERAYWTGYGEGNAWCPGAL---PDPEIVRMVEARKSLGE-EYTEDYEQP 164 + A + +A+E Y G+ + GA DP+++ + K + EY +D+E+ Sbjct: 2537 KAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKW 2596 Query: 165 RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224 + K S P + AKK L S V+YK + +++ + D +++ ++ LQS Sbjct: 2597 KTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCLPDQSDVIHARQAYDLQS 2651 Query: 225 DVRYTEDYEQQRGKG-------------------------------SFPAMITPAYQIAK 253 D Y D + +G G F +++ + Sbjct: 2652 DNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLA 2711 Query: 254 RANELASDVR-YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSF 311 + N + + R Y + + K+ + E +L ++ Y + Y EE + KG Sbjct: 2712 KNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYD 2771 Query: 312 PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371 + + AK + ++AS+ KY++ + K G H + +D+ + + V K+ S+ Sbjct: 2772 MRVDAIPIKAAKASRDIASEFKYKEGYRKQLGH-HIGARAIRDDPKMMWSMHVAKIQSDR 2830 Query: 372 EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431 EYKKD E + + + K SD YK NY + ++ + +H Sbjct: 2831 EYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYK-NYLH----QWTCLPDQSDVIH 2885 Query: 432 AMKVGSLASNVAYKAD--YKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489 A + L S+ YK+D + I + + + A ++ L D YRQ D+ K++ Sbjct: 2886 ARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEI--LSDKIYRQPPDRFKFT 2943 Query: 490 SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549 SVTD+ + V AK NA ++ Y ++K+K + D P+++ A+ N +SE YK Sbjct: 2944 SVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKL 3003 Query: 550 GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605 E+ K KG++++ DA+ ++AAKAS ++ S+ KYK+ Y K G +G D +++ S Sbjct: 3004 ANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWS 3063 Query: 606 LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665 + +AK+ S+ EYKK FE+ KT+F P+DM+ + AKK QTL SD+DY+ LHE+T LP+ Sbjct: 3064 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQ 3123 Query: 666 MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725 A++AY LQS+ YK+DL W++G+GW+ GS+++ + K+A +++S+ YRQ D+L Sbjct: 3124 NDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKL 3183 Query: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785 KFTSVTDS + AK + + Y ++ Q I D P + AR N N SE L Sbjct: 3184 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESL 3243 Query: 786 YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845 Y+ + E K +G++LR D++ +AAKA RD+AS+ KYKE Y + G IGA+ V D ++ Sbjct: 3244 YRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKI 3303 Query: 846 SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905 SL ++K+QS+ EYKK FE K++ +DM+ +V A+K Q L +DV YK H + L Sbjct: 3304 MWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICL 3363 Query: 906 PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965 P + A+KAY LQSDN Y++D++WMKG+GWV SL V +AK+AGEL+S+ YRQ P Sbjct: 3364 PDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRP 3423 Query: 966 DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025 + LKFTSI DTPE V A+ + RLY E +N K D PE++LAKLN +N S Sbjct: 3424 ETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYS 3483 Query: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085 + YK + + + GY LRLDA+P QAAKAS +I SDYKYKE + K G +G+R+++DD Sbjct: 3484 DKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDD 3543 Query: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145 + S++ +QSD YKK FE K +F P+DM +V AKK Q L S+ DYKHPL ++ Sbjct: 3544 PKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEW 3603 Query: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205 T L + + A+KA+ LQS+ +Y+SDL ++RG+ V G++E+E K+A E++S+ KYR Sbjct: 3604 TCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYR 3663 Query: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265 Q K+T +TDTP ++ AK + ++ LY A + + + P+ + AK+N+A Sbjct: 3664 QPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSA 3723 Query: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325 N+S Y + W + + Y L +A+ ++A+AS DIASD+ Y+ + K++G IG QS+ Sbjct: 3724 NISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSI 3783 Query: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385 DDP+I G++QSE +Y++ + +F P+DM+ ++ AK Q L +D DYR Sbjct: 3784 EDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYL 3843 Query: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445 H++T +P+ + AKKA+ LQS+ YK+DL ++GIGW+ SP++ K A + ++ Sbjct: 3844 HEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDS 3903 Query: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502 YR ++K+T++VD+P++V AK++ + + YR D S+H ++PD P+ Sbjct: 3904 VYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIH---IMPDTPEINL 3960 Query: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562 AR NAL++S+K+YR W++ +AG D RLDAIP Q A+ASREIASD++YK + +G Sbjct: 3961 ARANALNVSNKLYREGWDEMKAGC-DVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019 Query: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622 +G + DD +++ L +LQ++ EY+ D+AK +++ S D +L +K SQ L SD+ Sbjct: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079 Query: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682 YR L Q TC P+Q + A+KA++LQSD YK+DL RG+GW P S V A+ AA Sbjct: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139 Query: 1683 EL 1684 ++ Sbjct: 4140 DI 4141 Score = 979 bits (2530), Expect = 0.0 Identities = 592/1719 (34%), Positives = 941/1719 (54%), Gaps = 108/1719 (6%) Query: 55 HAHNPKNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHW--DMKS--KDKEG 110 + +P FTS+ +P+ + + + +S I + GE K + D+ + K Sbjct: 1228 YRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCN 1287 Query: 111 APNRQPLANERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE--YTEDYEQPRGK- 167 A N + +R + +GN A+P + +A +++ + Y E YE+ +GK Sbjct: 1288 AYNISDVCYKRDWHDLIAKGNNVLGDAIP----ITAAKASRNIASDYKYKEAYEKSKGKH 1343 Query: 168 -GSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDV 226 G P +L S EYK+ ++ T TP + S A++ DV Sbjct: 1344 VGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENT----KTSYHTPGDMVSITAAKMAQDV 1399 Query: 227 RYTEDYEQQRGKGSF--PAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEG 284 +Y+Q ++ AM + + + N++ SD Y +Y ++G+ IG+ Sbjct: 1400 ATNVNYKQPLHHYTYLPDAM---SLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGS-- 1454 Query: 285 ILTRECADQYGQGYPE-EYEEHRGKGSFPAM-----ITPAYQNAKKAHEL---------- 328 L E + G E +Y +H F ++ + A N K+ +L Sbjct: 1455 -LEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLK 1513 Query: 329 ---------------------ASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367 SD Y+ D+ K A Y P D + + A+S + Sbjct: 1514 HKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTI-AKGYDLRP--DAIPIVAAKSSRNI 1570 Query: 368 VSEVEYKKDLESSRGHSINYC---ETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVG 424 S+ +YK+ E ++G + + + P+ + ++K SD +YK+ Y+ + + Sbjct: 1571 ASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLD 1630 Query: 425 MDRRTLHAMKVGSLASNVAYKADYKHDIV------------------DYNYPATLTPSYQ 466 M T A K +A+N Y+ Y H + D Y + T ++ Sbjct: 1631 MVSVTA-AKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFT-NWM 1688 Query: 467 TAMKLVP---------------LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 511 + VP L + YRQ +KLK++ DT + K N + Sbjct: 1689 KGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRL 1748 Query: 512 YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571 Y + K+K + D P ++ ++ N S+ YK GWE+ K KG++++ DA+++ AA Sbjct: 1749 YTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAA 1808 Query: 572 KASGELASNIKYKEEYEKTKGKAMG----TADSRLLHSLQIAKMSSEVEYKKGFEESKTR 627 +AS ++AS+ KYK+ YE+ KGK +G D +L+H +Q+AKM S+ EYKKG+E+SKT Sbjct: 1809 RASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTS 1868 Query: 628 FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 687 FH P+DM+++ AKK+Q +A++ +YR +H Y +LP+ M + AK +QS+ QYKAD Sbjct: 1869 FHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADY 1928 Query: 688 A-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQ 746 A +MKG+GWL GSL E+ KKA +++SEK YRQ D LK++++ DS M A+ + ++ Sbjct: 1929 ADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIM 1988 Query: 747 SGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLT 806 + YK E + I D P + A+ANA N+S+KLYK S E K KG++LR D++ Sbjct: 1989 NEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIP 2048 Query: 807 FLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED 866 AAKA RD+AS+ KYK +YE+ +GK++G + ++ D ++ HS+Q++K+QS+ EYKK +E+ Sbjct: 2049 IKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYEN 2108 Query: 867 TKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQY 926 TK+ H DM+ + A+ AQ T+ YK H + LP M +E + +QSDN+Y Sbjct: 2109 TKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEY 2168 Query: 927 RADV-KWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARIS 985 + D +W KG+GW GSL VE+AKKA E S++KYRQHP +F + D+ +MV A+ + Sbjct: 2169 KQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQN 2228 Query: 986 YTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRL 1045 LY K D P++L AK N S+ YK W + GY L + Sbjct: 2229 AHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPV 2288 Query: 1046 DALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKK 1105 DA+ Q AKAS +I SDYKYK+ + K G +G RSL+DD L S+ +QS+ YKK Sbjct: 2289 DAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKK 2348 Query: 1106 GFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQS 1165 FE K +F P+DM +V AKK Q L S+ DYK+ L Q+T L + + AKK ++LQS Sbjct: 2349 DFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQS 2408 Query: 1166 ENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHA 1225 ENLY+SDL ++RG+ G+LE E K+ASE+ISE KYRQ P K+T++ D +++ A Sbjct: 2409 ENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLA 2468 Query: 1226 KFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYK 1285 K + + ++RLY+ A + + + + P+ + AK N N SD Y+ + L+ +GY Sbjct: 2469 KTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYD 2528 Query: 1286 LTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQ 1345 L ++A+P +AA+AS +IAS++ Y+ F K+ G IG +++ DDP++ + ++QS+ + Sbjct: 2529 LPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDRE 2588 Query: 1346 YRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHA 1405 Y++ + +F P+DM+ +V AK Q L SD DY+ H++T LP+ + A++A+ Sbjct: 2589 YKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYD 2648 Query: 1406 LQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDL 1465 LQS+ YKSDL +KGIGW+ S + E K+A +++S+ YR+ PD KF++++DS + Sbjct: 2649 LQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPM 2708 Query: 1466 VHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAG 1525 V AKN+ + N R+Y + ++PD P+ A+ N ++ S+K+Y+ E+ + Sbjct: 2709 VLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRK 2768 Query: 1526 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1585 YD R+DAIP + A+ASR+IAS+F+YKE + + G IG R++ DDP+M ++V ++QS Sbjct: 2769 GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQS 2828 Query: 1586 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1645 D EYKKDF K +++F S D G++ AK+ Q L SDV Y+ L Q TC P+Q + HA++ Sbjct: 2829 DREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQ 2888 Query: 1646 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684 A+ LQSD YKSDL RG+GW GS VE +RA E+ Sbjct: 2889 AYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEI 2927 Score = 794 bits (2051), Expect = 0.0 Identities = 480/1477 (32%), Positives = 792/1477 (53%), Gaps = 62/1477 (4%) Query: 229 TEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTR 288 T DYEQ + S PA+ PA +A+ A+ + R + + + P I ++ Sbjct: 39 TSDYEQS--ETSKPALAQPA--LAQPASAKPVERRKVIRKKVDPSKFMTPYIAH----SQ 90 Query: 289 ECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY 347 + D + Y E++E+ +G+ TP + KK + S++KYR D + K H Sbjct: 91 KMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHV 150 Query: 348 HSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNK 407 A+D ++ A+ V++ VS+V YK++ E ++ + + P+ K + S Sbjct: 151 DE-KAKD---IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKL 206 Query: 408 YKENYQ--NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSY 465 Y E+++ + Y RR A K S+VAYK + P P Sbjct: 207 YTEDWEADKSLFYPYNDSPELRRVAQAQKA---LSDVAYKKGLAEQQAQFT-PLADPPDI 262 Query: 466 QTAMKLV-PLKDANYRQSIDKLKYSSVTDTP--QIVQAKINAQQLSHVNYRADYEKNKLN 522 + A K+ + Y++ + ++TP ++ A++NA +S Y+ D+E K Sbjct: 263 EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322 Query: 523 -YTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAM---SLLAAKASGELA 578 Y + + P+ K S+VKYKE +EK KGK L A L KA+G+ Sbjct: 323 IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382 Query: 579 SNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIR 638 S+ YKE YEKTK K++ ++ +F L + N Sbjct: 383 SDKLYKENYEKTKAKSINYCET-------------------------PKFKLDTVLQNFS 417 Query: 639 HAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTE 698 KK + D + L Y ED K S+ YKA+ +G G+ + Sbjct: 418 SDKKYK----DSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQ 473 Query: 699 GSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQS 758 +A K + Y+ D+ KFT VTDS + A+ + + S + YKA +E Sbjct: 474 TITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESE 533 Query: 759 VHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLAS 818 + I D P F+Q + NA NLS+ LYK WE KAK F++++D++ LAAKA S Sbjct: 534 KFKCHIPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 593 Query: 819 EVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQ----CHVS 874 +V YK+DYE+++GK+IG + D +M HSL+++K QS+ YK+ +E TK++ C Sbjct: 594 DVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETP 653 Query: 875 LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMK 934 + ++ D+ K H+ D K SD Y+A+ + K Sbjct: 654 KYQLDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDK 713 Query: 935 GMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLY 994 G + +A K + + Y+ HPD KFT++ D+P ++QA+++ Q D Y Sbjct: 714 GKCYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNY 773 Query: 995 REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1054 + + E K AD P+ + ++NA N+S+ YK+ W K + + +++DA+P AAK Sbjct: 774 KAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAK 833 Query: 1055 ASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQF 1114 A+ + SD YK+ +EK KG+M+G+ S+ DD + HS+ QSD Y+K +E SK + Sbjct: 834 ANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIY 893 Query: 1115 HLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN 1174 PLDM + AKK+Q +AS+ DYKH L Y+ + + + AKKA+ LQS+ Y++D N Sbjct: 894 TAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYN 953 Query: 1175 -FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITN 1233 +M+G V G+LE+E K+AS++++E KYRQHP + K+T++ D P + +K + + Sbjct: 954 SWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRS 1013 Query: 1234 ERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPF 1293 + YKA GE+ H+Y + LP+FI+AK NA N+S+ YK ++L +GY L +A+P Sbjct: 1014 DIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPI 1073 Query: 1294 QAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS 1353 +AA+A+ ASD Y+ D+ K +GK++G QS++DDP++ H + ++QS+ +Y++ + Sbjct: 1074 RAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKT 1133 Query: 1354 QAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYK 1413 +++++ P DM ++V AK AQ + S+ +Y+ H +T LP+ + + +K +QS+ YK Sbjct: 1134 KSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYK 1193 Query: 1414 SDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSY 1472 D MKGIGW+ + S +E KKAG+ ++E KYR+ PD++KFT++VDSP +V AK + Sbjct: 1194 EDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNT 1253 Query: 1473 MHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLD 1532 ++ +Y++ + H+YT+ PD P F +A+ NA ++SD Y+ W A + D Sbjct: 1254 KQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGD 1313 Query: 1533 AIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKD 1592 AIP A+ASR IASD++YKEA+ + +G +G+RS+ DDP++ H++NV +LQSD EYKK+ Sbjct: 1314 AIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKN 1373 Query: 1593 FAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSD 1652 + +++ +H+ D + AK +Q +A++V+Y+QPL T P+ + L H + +Q+QSD Sbjct: 1374 YENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433 Query: 1653 VKYKSDLN-LTRGVGWTPPGSYKVEMARRAAELANAR 1688 YK + N +G+GW P GS +VE ++A + N R Sbjct: 1434 NVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNER 1470 Score = 764 bits (1972), Expect = 0.0 Identities = 493/1582 (31%), Positives = 817/1582 (51%), Gaps = 70/1582 (4%) Query: 140 DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198 DP+I+ + K + EY +D+E+ + + S P + AKK L S V+YK Sbjct: 3300 DPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDML-GIVLAKKCQTLVSDVDYKHPLH 3358 Query: 199 ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258 E I + D +++ ++ LQSD Y D E +G G P + AKRA EL Sbjct: 3359 EWIC----LPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVR-AKRAGEL 3413 Query: 259 ASDVRYHQQYQK----------EMRGMAGPAIGAEGILTRECADQYGQG----------- 297 SD Y Q+ + E A+ L E D + Sbjct: 3414 LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIM 3473 Query: 298 -------------YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344 Y EE + +G + Q AK + ++ASD KY++ + K G Sbjct: 3474 LAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGH 3533 Query: 345 AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404 H + +D+ + + V K+ S+ EYKK+ E + + + K S Sbjct: 3534 -HIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVS 3592 Query: 405 DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPS 464 D YK H + + + A K L S+ YK+D +++ P Sbjct: 3593 DIDYK-----HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSD-----LEWLRGIGWVPI 3642 Query: 465 YQTAMKLVP-----LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKN 519 ++ V L D YRQ D+LK++ +TDTP+IV AK NA +S Y ++ + Sbjct: 3643 GSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDAD 3702 Query: 520 KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELAS 579 K + + D P ++ AK+N+ S+ Y +GW+++K K ++++ DA+S+ +AKAS ++AS Sbjct: 3703 KTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIAS 3762 Query: 580 NIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 635 + KYKE YEK KG +G D +++ ++ K+ SE EYKK F++ KT+F P+DM+ Sbjct: 3763 DYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDML 3822 Query: 636 NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 695 +I AKK QTL +D+DYR LHE+T +P+ AKKAY LQS+ YKADL W++G+GW Sbjct: 3823 SILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGW 3882 Query: 696 LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN 755 + +GS + + K A + + YR V LK+TS+ D+ ++ AK + E S Y+ Sbjct: 3883 MPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVW 3942 Query: 756 EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD 815 ++ I D P ARANA N+S KLY+ W+ KA G ++RLD++ AAKA R+ Sbjct: 3943 DKDKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASRE 4001 Query: 816 LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL 875 +AS+ KYK D+E+ +G +G + D+++ +L KLQ+E EY+ + K++ + Sbjct: 4002 IASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPV 4061 Query: 876 DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKG 935 DM+ ++H++ +Q L +D+ Y+ H +T +P V AKKAY LQSDN Y+AD++W++G Sbjct: 4062 DMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRG 4121 Query: 936 MGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYR 995 +GW+ S++V AK A ++ SEKKYR + L FT + D + V A+ S D YR Sbjct: 4122 IGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYR 4181 Query: 996 EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1055 + K YT T + P + A+ A + + YKE W + + GY L DA+PF A Sbjct: 4182 KDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHH 4240 Query: 1056 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1115 ++ S+ KYK K KG +G ++ DD L +A +Q++ YK+ + +KA+ + Sbjct: 4241 CNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKIN 4300 Query: 1116 LPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNF 1175 +P DM +++ AK+ QTL S+ DY++ L Q+ + + A+KA+ LQS+N+YR+DL + Sbjct: 4301 IPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEW 4360 Query: 1176 MRGVACVIPGTLEIEGRKKASELISESKYRQH--PHSFKYTAVTDTPNLLHAKFSNQITN 1233 +RG+ + +++ K E++S+ KY+++ + + +V D P ++ AK ++ + Sbjct: 4361 LRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQS 4420 Query: 1234 ERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPF 1293 + YK A+ +YT + P +K S YK +W +A GY L +P Sbjct: 4421 DVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPI 4480 Query: 1294 QAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS 1353 A+ + + S+ Y+ + K++G + + + + P + HC +++S L YR+ + Sbjct: 4481 VGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDT 4540 Query: 1354 QAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYK 1413 +A H+P DM++ V AK Q + SD +YR +H++T+L E+ + + A + S+ YK Sbjct: 4541 KANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYK 4600 Query: 1414 SDLIGMKGIGWLALRSPQMESAKKAGELISETKYRK--KPDSIKFTTVVDSPDLVHAKNS 1471 DL +KGIG +PQ+ AKK+ +L S+ +Y K + + V D+P V A S Sbjct: 4601 DDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQS 4660 Query: 1472 YMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRL 1531 ++ +E Y+ + +YT + + D+ R R S +Y+ +W++ +A SY Sbjct: 4661 GINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPS 4720 Query: 1532 DAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKK 1591 + A+ + +AS +Y+E + + + L RSVDDDP L VG+L D Y+ Sbjct: 4721 STLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRS 4780 Query: 1592 DFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQS 1651 + K++ + H D ++ AK SQ+ S++ YR L + C P+ H +K S Sbjct: 4781 VYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQIS 4840 Query: 1652 DVKYKSDLNLTRGVG---WTPP 1670 D+ YK DLN +G+G W P Sbjct: 4841 DIVYKDDLNWLKGIGCYVWDTP 4862 Score = 730 bits (1885), Expect = 0.0 Identities = 538/1840 (29%), Positives = 901/1840 (48%), Gaps = 183/1840 (9%) Query: 38 MMLSVNNFVSHQKKPYCHAHNPKNNTFTSVYHTPLNL----NVRTFPEAISGIHDQEDGE 93 M+L+ NN ++ + Y A + T + TP L N + E + + +E Sbjct: 2708 MVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKR 2767 Query: 94 QCKSVFHWDMK--SKDKEGAPNRQPLANERAYWTGYGEGNAWCPGALP---DPEIVRMVE 148 + +DM+ + + A + +A+E Y GY + GA DP+++ + Sbjct: 2768 K-----GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMH 2822 Query: 149 ARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTV 207 K + EY +D+E+ + K S P + AKK L S V+YK + +++ + Sbjct: 2823 VAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCL 2877 Query: 208 VDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQ 267 D +++ ++ LQSD Y D + RG G + ++ + + KRA E+ SD Y Q Sbjct: 2878 PDQSDVIHARQAYDLQSDNMYKSDLQWMRGIG-WVSIGSLDVEKCKRATEILSDKIYRQP 2936 Query: 268 ---------------------------------YQKEMRGMAGPAIGAEGILTRECADQY 294 + K+ + E +L R+ Y Sbjct: 2937 PDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINY 2996 Query: 295 GQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353 + Y EE + KG AK + ++ SD KY+ + K G H + + Sbjct: 2997 SETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGH-HIGARNIE 3055 Query: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413 D+ + + V K+ S+ EYKKD E + + + K SD YK NY Sbjct: 3056 DDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYK-NYL 3114 Query: 414 NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP 473 + + + +HA + L S+ YK+D + P + Sbjct: 3115 HE----WTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEI 3170 Query: 474 LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLV 533 L D YRQ DKLK++SVTD+ + V AK NA ++ Y ++K+K + D P+++ Sbjct: 3171 LSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIM 3230 Query: 534 KAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGK 593 A+ N +SE Y++ E+ K +G++++ DA+ ++AAKAS ++AS+ KYKE Y K G Sbjct: 3231 LARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGH 3290 Query: 594 AMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASD 649 +G D +++ SL IAK+ S+ EYKK FE+ KTR+ P+DM+ I AKK QTL SD Sbjct: 3291 HIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSD 3350 Query: 650 LDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKA 709 +DY+ LHE+ LP+ A+KAY LQS+ YK+DL WMKG+GW+ SL + +AK+A Sbjct: 3351 VDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRA 3410 Query: 710 GQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEP 769 G+L+S+ YRQR + LKFTS+TD+ + AK + + Y + + D P Sbjct: 3411 GELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTP 3470 Query: 770 LFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERS 829 + A+ N N S+KLYK + E K +G++LRLD++ AAKA RD+AS+ KYKE Y + Sbjct: 3471 EIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQ 3530 Query: 830 RGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHL 889 G IGA++++ D +M S+ ++K+QS+ EYKK FE K++ +DM+ +V A+K Q L Sbjct: 3531 LGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQIL 3590 Query: 890 ATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQA 949 +D+ YK H +T LP V A+KAY LQSD Y++D++W++G+GWV GS+ VE+ Sbjct: 3591 VSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKV 3650 Query: 950 KKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTA 1009 K+AGE++S++KYRQ D LKFT I DTPE+V A+ + LY E + K Sbjct: 3651 KRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMP 3710 Query: 1010 DLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAF 1069 D P++LLAK N+ NIS+ Y + W + + Y LR DA+ ++AKAS +I SDYKYKEA+ Sbjct: 3711 DTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAY 3770 Query: 1070 EKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKA 1129 EK KG +G++S+EDD + +++A +QS+ YKK F+ K +F P+DM +++ AKK Sbjct: 3771 EKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKC 3830 Query: 1130 QTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEI 1189 QTL ++ DY++ L ++T + + + AKKA+ LQS+ LY++DL ++RG+ + G+ E+ Sbjct: 3831 QTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEV 3890 Query: 1190 EGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYT 1249 K A + +S YR + KYT++ DTP ++ AK + + + Y+ + + Sbjct: 3891 LRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIH 3950 Query: 1250 MTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFL-- 1307 + PE A+ NA N+S+ Y+E W ++A G + ++A+P QAA+AS +IASD+ Sbjct: 3951 IMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYK 4009 Query: 1308 ------------------------------------YRHDFVKERGKLIGPQSVR----- 1326 YR D+ K + K+ P + Sbjct: 4010 LDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHS 4069 Query: 1327 -----------------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1363 D + ++ +LQS+ Y+ + +P D Sbjct: 4070 KNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDS 4129 Query: 1364 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1421 V + HAK+A + S+ YRT+ FT + + + AK++ + +++Y+ D K Sbjct: 4130 VSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKS 4189 Query: 1422 IGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCN----E 1477 + +P + +A++A ++ + Y++ + K T + PD V +++ HCN E Sbjct: 4190 -KYTLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH-HCNDVQSE 4247 Query: 1478 RMYRSGDAESLHRYTLIP---DHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAI 1534 Y++ + Y +P D P ++++Y+ + +T+A + D + Sbjct: 4248 LKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKA-KINIPADMV 4306 Query: 1535 PFQTARASREIASDFRYKEAF---------------LRDRGLQ--------------IGY 1565 A+ + + SD Y+ + LQ IG+ Sbjct: 4307 SVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGW 4366 Query: 1566 RSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYR 1625 +D ++ N + S +YKK+ ++ F S D P ++ AK + SDV Y+ Sbjct: 4367 IPLDSVDHVRVTKNQ-EMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYK 4425 Query: 1626 QPLPQP----TCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1681 + + T P+ + H++ +L S + YK T+ G+T Y + + Sbjct: 4426 ETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKH 4485 Query: 1682 AELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILH 1721 A+L N+ + Y+ + G + +G+V + ++H Sbjct: 4486 ADLVNS-----ELKYKETYEKQKGHYLAGKVIGEFPGVVH 4520 Score = 590 bits (1522), Expect = e-168 Identities = 442/1548 (28%), Positives = 737/1548 (47%), Gaps = 120/1548 (7%) Query: 147 VEARKSLGEEYTE-DYEQPRGKGSFPAMI-TPAYQRAKKANQLASQVEYKRGHDERISRF 204 VE K GE ++ Y QP + F + TP AK S+ Y D + Sbjct: 3647 VEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSI 3706 Query: 205 STVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRY 264 + DTP++L +K+ + S YT+ +++ + K + + AK + ++ASD +Y Sbjct: 3707 HVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKY 3766 Query: 265 HQQYQKEMRGMAGPAIGAEGILTRE---CADQYG-----QGYPEEYEEHRGKGSFPAMIT 316 + Y+K+ G IGA+ I CA G + Y +E+++ + K S P + Sbjct: 3767 KEAYEKQ----KGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDML 3822 Query: 317 PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKD 376 + AKK L +DI YR ++ + +P Q++++ QA+ L S+ YK D Sbjct: 3823 -SILLAKKCQTLVTDIDYRNYLHE------WTCMPDQNDII--QAKKAYDLQSDALYKAD 3873 Query: 377 LESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG 436 LE RG +P+ V Sbjct: 3874 LEWLRGIGWMPQGSPEVLRVKN-------------------------------------- 3895 Query: 437 SLASNVAYKADYKHDIVDYNYPATL-TPSYQTAMKLVP-LKDANYRQSIDKLKYS--SVT 492 A N+ + Y+ +V+ Y + + TP A + YR+ DK K S + Sbjct: 3896 --AQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMP 3953 Query: 493 DTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWE 552 DTP+I A+ NA +S+ YR +++ K + D + AK + ++ S+ KYK E Sbjct: 3954 DTPEINLARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013 Query: 553 KTKGK--GFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAK 610 K KG G D + A + +L + +Y+ ++ K K AK Sbjct: 4014 KQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWK-----------------AK 4056 Query: 611 MSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQW 670 + S V DM++I H+K +Q L SD+DYR LH++T +P+ Sbjct: 4057 IQSPV-----------------DMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQ 4099 Query: 671 AKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSV 730 AKKAY LQS+ YKADL W++G+GW+ S+++ AK A + SEK YR +++ L FT V Sbjct: 4100 AKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPV 4159 Query: 731 TDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSW 790 D AK+S E+ + Y+ + +YT++ + PL A+ A L + LYK W Sbjct: 4160 DDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKEGW 4218 Query: 791 ENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQ 850 E QKA G+ L D++ F+ A D+ SE+KYK ++ + +G +G ++ D ++ Sbjct: 4219 ERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEH 4278 Query: 851 MSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMK 910 ++Q+E YK+ + TK++ ++ DMV ++ A++ Q L +D+ Y+ H + P Sbjct: 4279 AGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQND 4338 Query: 911 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQH--PDAL 968 V A+KAY LQSDN YRAD++W++G+GW+ S++ + K E++S+ KY+++ + Sbjct: 4339 VIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALENYP 4398 Query: 969 KFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETR 1028 F S+ D PE+V A+I+ D Y+E K YT + D P + +K S Sbjct: 4399 NFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTIL 4458 Query: 1029 YKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISL 1088 YK +W + GY L +P AK + + S+ KYKE +EK KG L + + + + Sbjct: 4459 YKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGV 4518 Query: 1089 AHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSL 1148 H + ++S +NY+K +E +KA H+P DM V AK+ Q + S+ +Y+H Q+TSL Sbjct: 4519 VHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSL 4578 Query: 1149 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ-- 1206 E+ + + A ++ S+N+Y+ DLN+++G+ C + T +I KK+ +L S+ +Y Sbjct: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAG 4638 Query: 1207 HPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAAN 1266 + Y VTDTP + A S +E YK + +YT L ++ R + Sbjct: 4639 KENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNL 4698 Query: 1267 LSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVR 1326 S YKE+W ++A Y L L A+ +AS YR ++ K + P+SV Sbjct: 4699 YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVD 4758 Query: 1327 DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYH 1386 DDP C R+G+L + YR ++ + H+ DMV +V AK++Q S+ DYR + H Sbjct: 4759 DDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLH 4818 Query: 1387 KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETK 1446 ++ P+ +K S++ YK DL +KGIG +P++ AK A +L + K Sbjct: 4819 EWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIK 4878 Query: 1447 YRKKPDSIK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH-RYTLIPDHPDFTRA 1503 Y+ + + V D+P V A S ++ +Y S+ + D RA Sbjct: 4879 YKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRA 4938 Query: 1504 RLNALHL-SDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562 L+A L S +Y+ S G Y D F+ + +R ++S F+YKEA+ + Sbjct: 4939 -LHAYKLQSSNLYKTSLRTLPTG-YRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKA-- 4994 Query: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622 GY D H V + S+ Y++ + K + + H++ D P + Q K++Q+ S++ Sbjct: 4995 YGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSEL 5054 Query: 1623 HYRQPL----PQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666 Y+ P + H + + SD+KYK DL + +G G Sbjct: 5055 IYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFG 5102 Score = 514 bits (1325), Expect = e-145 Identities = 435/1660 (26%), Positives = 744/1660 (44%), Gaps = 150/1660 (9%) Query: 119 NERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYT--EDYEQPRGK--GSFPAMI 174 +++ Y G+ E D ++ +A + + +Y E YE+ +G G+ Sbjct: 3726 SQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIED 3785 Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISRFSTVV-------------------------- 208 P A A ++ S+ EYK+ + ++FS+ V Sbjct: 3786 DPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHE 3845 Query: 209 -----DTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFP--------------------- 242 D +++++K LQSD Y D E RG G P Sbjct: 3846 WTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVY 3905 Query: 243 -----------AMITPAYQIAKRANELASDVRYHQQYQKEMRGM-AGPAIGAEGILTREC 290 + TP +AK E S +Y + + K+ + P + Sbjct: 3906 RTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANA 3965 Query: 291 ADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY-HS 349 + + Y E ++E + G + Q AK + E+ASD KY+ D K KG HY + Sbjct: 3966 LNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKG--HYVGT 4022 Query: 350 LPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYK 409 L A+D+ ++ A +KL +E EY+ D + + + + SD Y+ Sbjct: 4023 LTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYR 4082 Query: 410 ENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK---------HDIVDYNYPAT 460 NY + ++ + + A K L S+ YKAD + +D V N+ Sbjct: 4083 -NYLH----QWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKH 4137 Query: 461 LTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520 + + YR I+ L ++ V D V AK + + L + YR D+ K Sbjct: 4138 AADIF---------SEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATK 4188 Query: 521 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580 YTL + P L A+ A++ + YKEGWE+ K G+ + DA+ + A ++ S Sbjct: 4189 SKYTL-TETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSE 4247 Query: 581 IKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVN 636 +KYK E+ K KG +G D +L+ ++ +E YK+ + ++K + ++P DMV+ Sbjct: 4248 LKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVS 4307 Query: 637 IRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWL 696 + AK+ QTL SD+DYR LH++ P+ A+KAY LQS+ Y+ADL W++G+GW+ Sbjct: 4308 VLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWI 4367 Query: 697 TEGSLNLEQAKKAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAKKSQELQSGVAYKAG 754 S++ + K +++S+ Y++ E F SV D ++ AK + QS V YK Sbjct: 4368 PLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKET 4427 Query: 755 NEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKR 814 ++ +YT S D P ++ S LYK +WE KA G+ L + + AK Sbjct: 4428 FNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHAD 4487 Query: 815 DLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVS 874 + SE+KYKE YE+ +G + K + + H L K++S L Y+K +EDTK+ H+ Sbjct: 4488 LVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIP 4547 Query: 875 LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMK 934 DM++ V A++ Q++ +D+ Y+ H +T+L + V + A + SDN Y+ D+ W+K Sbjct: 4548 NDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLK 4607 Query: 935 GMGWVATGSLNVEQAKKAGELISEKKYRQ--HPDALKFTSIKDTPEMVQARISYTQAVDR 992 G+G + + AKK+ +L S+ +Y + + + DTP V A S A + Sbjct: 4608 GIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEV 4667 Query: 993 LYREQGENIKHHYTPTADLPEVLLAKLNAMNI-SETRYKESWSKLRDGGYKLRLDALPFQ 1051 Y+E IK YT + + + N N+ S YKE+W +++ Y L L Sbjct: 4668 KYKENYHQIKDKYTTVLETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYILPSSTLSLT 4726 Query: 1052 AAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSK 1111 AK + S KY+E +EK K RS++DD + A + L D Y+ +E +K Sbjct: 4727 HAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNK 4786 Query: 1112 AQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRS 1171 + H+ DM +V AK +Q S DY+ L ++ + +K S+ +Y+ Sbjct: 4787 MKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKD 4846 Query: 1172 DLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNLLHAKFSN 1229 DLN+++G+ C + T EI K A +L + KY+ H + Y VTDTP + A S Sbjct: 4847 DLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSG 4906 Query: 1230 QITNERLY------KAAGEDARHEYTMTLGLPEFIRA-KTNAANLSDARYKESWRNLRAQ 1282 + ++ +Y G+ A T T+ L + A K ++NL YK S R L Sbjct: 4907 KQLSDAVYHYDYVHSVRGKVA--PTTKTVDLDRALHAYKLQSSNL----YKTSLRTL-PT 4959 Query: 1283 GYKLTIEALPFQAARASGDIASDFLYR--HDFVKERGKLIGPQSVRDDPRIQHCRRMGQL 1340 GY+L + F+ + + ++S F Y+ ++ K G +GP+ D H RR+ + Sbjct: 4960 GYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVHVRRVNNV 5015 Query: 1341 QSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK----FTALPEDLK 1396 SE YR + + H D + K Q S+ Y++ + K +LP + Sbjct: 5016 TSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQ 5075 Query: 1397 MAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSI-- 1454 + + + S+++YK DL +KG G +P M ++ +L S Y K + Sbjct: 5076 VIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRD 5135 Query: 1455 KFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRA----RLNALHL 1510 K+ V+D+P+ + H +E +YR+ + +T +PD PD RA +L + +L Sbjct: 5136 KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYL 5195 Query: 1511 SDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDD 1570 ++ AG+ L + A+ +++ S+ +YK ++ ++ Y V D Sbjct: 5196 YVELATKERPHHHAGNQTTAL-----KHAKDVKDMVSEKKYK---IQYEKMKDKYTPVPD 5247 Query: 1571 DPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQ---- 1626 P + SD YK+ F K++ ++H+ D ++ ++ S + Y++ Sbjct: 5248 TPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMS 5307 Query: 1627 PLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666 L P++ H + SDVKYK DL +G+G Sbjct: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347 Score = 441 bits (1133), Expect = e-123 Identities = 435/1717 (25%), Positives = 739/1717 (43%), Gaps = 149/1717 (8%) Query: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 N +TS+ TP + ++ E IS +E ++ K+ H + + A + Sbjct: 3911 NLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSN 3970 Query: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180 + Y G+ E A C L D ++ +A + + +Y + + KG + +T Sbjct: 3971 KLYREGWDEMKAGCDVRL-DAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDN 4029 Query: 181 ----AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQR 236 A A++L ++ EY+ + ++ + VD +L SK L SD+ Y Q Sbjct: 4030 KIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWT 4089 Query: 237 GKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAG-PAIGAEGILTRECADQYG 295 +I AK+A EL SD Y + +RG+ P + AD + Sbjct: 4090 CMPDQNDVIQ-----AKKAYELQSDNVYKADLEW-LRGIGWMPNDSVSVNHAKHAADIFS 4143 Query: 296 QGYPEEYEEHRGKGSF-PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA-- 352 + ++Y +F P Y AK++ E+ DIKYR+D+N K P Sbjct: 4144 E---KKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH 4200 Query: 353 -----------------------------QDNLVLKQAQSVNKLVSEVEYKKDLESSRGH 383 D + A N + SE++YK + +GH Sbjct: 4201 TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH 4260 Query: 384 SINYCETPQFRNVSKISKFT------SDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG- 436 Y P R+ K+ F ++ YKE+Y H + D ++ A K G Sbjct: 4261 ---YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDY--HKTKAKINIPADMVSVLAAKQGQ 4315 Query: 437 SLASNVAYKADYKH---------DIV----------DYNYPATLTPSYQTAMKLVPLKDA 477 +L S++ Y+ +Y H D++ D Y A L + + +PL Sbjct: 4316 TLVSDIDYR-NYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADL--EWLRGIGWIPLDSV 4372 Query: 478 NY------RQSIDKLKYS-----------SVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520 ++ ++ + ++KY SV D P+IV AKIN+ S V Y+ + K K Sbjct: 4373 DHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAK 4432 Query: 521 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580 YT D P + +K KL+S + YK WE TK G+ + + ++ AK + + S Sbjct: 4433 GKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSE 4492 Query: 581 IKYKEEYEKTKG-----KAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 635 +KYKE YEK KG K +G ++H L KM S + Y+K +E++K H+P DM+ Sbjct: 4493 LKYKETYEKQKGHYLAGKVIGEFPG-VVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMM 4551 Query: 636 NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 695 N AK+ Q + SDL+YR H++T L E+ + A + S+ YK DL W+KG+G Sbjct: 4552 NHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGC 4611 Query: 696 LTEGSLNLEQAKKAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAKKSQELQSGVAYKA 753 + + AKK+ L S+ Y E + VTD+ A +S S V YK Sbjct: 4612 YVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKE 4671 Query: 754 GNEQSVHQYTISKDEPLFLQARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKA 812 Q +YT + + + R N NL S LYK +W+ KA + L +L+ AK Sbjct: 4672 NYHQIKDKYTTVLETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKN 4730 Query: 813 KRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCH 872 ++ LAS +KY+E+YE+ + + V D + L++ KL + Y+ +E K + H Sbjct: 4731 QKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIH 4790 Query: 873 VSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKW 932 + DMV +V A+ +Q +++ Y+ H + P + +K SD Y+ D+ W Sbjct: 4791 IVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNW 4850 Query: 933 MKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAV 990 +KG+G + + AK A +L + KY+ H + + + DTP VQA S Q Sbjct: 4851 LKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLS 4910 Query: 991 DRLYR-EQGENIKHHYTP---TADLPEVLLA-KLNAMNISETRYKESWSKLRDGGYKLRL 1045 D +Y + +++ P T DL L A KL + N+ YK S L GY+L Sbjct: 4911 DAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNL----YKTSLRTL-PTGYRLPG 4965 Query: 1046 DALPFQAAKASGEIISDYKYKEAFEKMK--GQMLGSRSLEDDISLAHSVYATSLQSDVNY 1103 D F+ K + + S +KYKEA+E K G LG + D+ H ++ S+ Y Sbjct: 4966 DTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVHVRRVNNVTSERLY 5021 Query: 1104 KKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPL----PQYTSLAEDLRLSCAKK 1159 ++ + K + H D + KK Q S YK SL ++ + Sbjct: 5022 RELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRY 5081 Query: 1160 AHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSF--KYTAVT 1217 + S+ Y+ DL ++G C + T ++ + +L S Y KY V Sbjct: 5082 VGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVL 5141 Query: 1218 DTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWR 1277 DTP + +E +Y+AAG+ + +T P+ +RAK S Y E Sbjct: 5142 DTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELAT 5201 Query: 1278 NLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRM 1337 R + + + A+ D+ S+ Y+ + K + K V D P + +R Sbjct: 5202 KERPH-HHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKY---TPVPDTPILIRAKRA 5257 Query: 1338 GQLQSELQYRRGATSSQAQFHLPMDMVHLVHAK----NAQALASDHDYRTQYHKFTALPE 1393 S+L+Y+ ++ ++H D + +V+ + + + +Y +Q + ++P+ Sbjct: 5258 YWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPD 5317 Query: 1394 DLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDS 1453 + + S+++YK DL +KGIG A +P A+K L S+ KY++ + Sbjct: 5318 RPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFER 5377 Query: 1454 IK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1511 K F V DSP H K + NE+ YR+ + +Y L+ D P A+ +S Sbjct: 5378 TKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQIS 5437 Query: 1512 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1571 YR ++E+++ +T + +++I SD YK + ++ GY ++ D Sbjct: 5438 QIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI-SDILYKLEY--NKAKPRGYTTIHDT 5494 Query: 1572 PRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQP 1631 P + H V SD +YK+ + +++S D + AK + ++ +++ Y++ Sbjct: 5495 PMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEAN 5554 Query: 1632 TC----DPEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1664 P++ A K+ QSD +YK D +G Sbjct: 5555 KAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591 Score = 409 bits (1051), Expect = e-113 Identities = 404/1636 (24%), Positives = 714/1636 (43%), Gaps = 200/1636 (12%) Query: 141 PEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 P+ +++ARK+ + Y D E RG G P + + + R K ++ SQ++YK+ Sbjct: 4334 PDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP-LDSVDHVRVTKNQEMMSQIKYKKN 4392 Query: 197 HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256 E F +VVD PE++ +K + QSDV+Y E + + +GK +F + TP +K Sbjct: 4393 ALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTF-SPDTPHISHSKDMG 4451 Query: 257 ELASDVRYH------QQYQKEMRGMAGPAIGAE--GILTRECADQYGQGYPEEYEEHRGK 308 +L S + Y + Y + P +GA+ ++ E Y E YE+ +G Sbjct: 4452 KLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELK------YKETYEKQKGH 4505 Query: 309 -------GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA 361 G FP ++ + ++ S + YR+ + K H + ++++ K+ Sbjct: 4506 YLAGKVIGEFPGVV-----HCLDFQKMRSALNYRKHYEDTKANVHIPN-DMMNHVLAKRC 4559 Query: 362 QSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYE 421 Q + +S++EY+ + E P V + SDN YK++ N ++G Sbjct: 4560 QYI---LSDLEYRHYFHQWT----SLLEEPNVIRVRNAQEILSDNVYKDDL-NWLKGIGC 4611 Query: 422 GVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQ 481 V + LHA K L S + Y A K ++ +YN T TP Y TA Sbjct: 4612 YVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNL-VTDTPLYVTA------------- 4657 Query: 482 SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541 VQ+ INA S V Y+ +Y + K YT + + + L Sbjct: 4658 ----------------VQSGINA---SEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNL 4698 Query: 542 FSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA--- 598 +S YKE W++ K + + +SL AK LAS+IKY+EEYEK K A+ T Sbjct: 4699 YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFK--ALYTLPRS 4756 Query: 599 ---DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK 655 D L++ K++ + Y+ +E++K + H+ DMV + AK +Q S++DYR + Sbjct: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLR 4816 Query: 656 LHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSE 715 LHE+ P+ +K S++ YK DL W+KG+G + + AK A L + Sbjct: 4817 LHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDD 4876 Query: 716 KNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQ 773 Y+ + + + + VTD+ A KS + S Y SV + + L Sbjct: 4877 IKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936 Query: 774 ARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSR-- 830 +A L S LYK+S G+ L D+ F K R ++S KYKE YE ++ Sbjct: 4937 RALHAYKLQSSNLYKTSLRTLPT-GYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY 4995 Query: 831 GKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLA 890 G +G KDV H +++ + SE Y++ + K + H + D + +K Q Sbjct: 4996 GYTLGPKDVP----FVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAV 5051 Query: 891 TDVGYKT----AEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNV 946 +++ YK+ + H +LP +V + + SD +Y+ D++ +KG G + ++ Sbjct: 5052 SELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDM 5111 Query: 947 EQAKKAGELISEKKYRQHPDAL--KFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 1004 +++ +L S Y + K+ + DTPE + + T + +YR G+ K Sbjct: 5112 VRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSI 5171 Query: 1005 YTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYK 1064 +T D P++L AK S+ Y E +K R + + AK +++S+ K Sbjct: 5172 FTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKK 5230 Query: 1065 YKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALV 1124 YK +EKMK + + D L + A SD+ YK+ F+ +K ++H D +V Sbjct: 5231 YKIQYEKMKDKYT---PVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIV 5287 Query: 1125 HAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL----YRSDLNFMRGVA 1180 + +K S YK + + H+ ++ + Y+ DL +++G+ Sbjct: 5288 YHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347 Query: 1181 CVIPGTLEIEGRKKASELISESKYRQ----HPHSFKYTAVTDTPNLLHAKFSNQITNERL 1236 C T + +K L S+ KY++ FKY A D+P H K++ Q+ NE+ Sbjct: 5348 CYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVA--DSPINRHFKYATQLMNEKK 5405 Query: 1237 YKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAA 1296 Y+A E + +Y + + P + AKT +S +Y++++ + + + + Sbjct: 5406 YRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTT 5465 Query: 1297 RASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ 1356 + + I SD LY+ ++ K + + G ++ D P + H R++ S+L+Y+ +++ Sbjct: 5466 KVNKQI-SDILYKLEYNKAKPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN 5522 Query: 1357 FHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTA----LPEDLKMAWAKKAHALQSELRY 1412 + D VH+ AK+A + ++ DY+ QY A P+ A K+ QS+ Y Sbjct: 5523 CTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEY 5582 Query: 1413 KSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFT--TVVDSPDLVHAKN 1470 K D +KG A + + S+ KY++K + T V D+P ++ AK Sbjct: 5583 KLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKT 5642 Query: 1471 SYMHCNERMYRSGDAESLHR--YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYD 1528 +E Y+ + L + YT +P+ D + H+SD Sbjct: 5643 VSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT--------------- 5687 Query: 1529 FRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNE 1588 YK+ F++++G + Y + + P +KH + V + QSD Sbjct: 5688 ---------------------NYKKKFVKEKG-KSNYSIMLEPPEVKHAMEVAKKQSDVA 5725 Query: 1589 YKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQ 1648 Y+KD AK + + D+P + +A ++ + AS+V YR +H ++ Sbjct: 5726 YRKD-AKENLHYTTVADRPDIKKATQAAKQASEVEYRA--------------KHRKEGSH 5770 Query: 1649 LQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQ 1708 G + G +EMA++AA+L++ Q YR E G + Sbjct: 5771 -----------------GLSMLGRPDIEMAKKAAKLSS------QVKYRENFDKEKG--K 5805 Query: 1709 SGEVNPDATEILHVKK 1724 + + NP +++ V K Sbjct: 5806 TPKYNPKDSQLYKVMK 5821 Score = 351 bits (900), Expect = 4e-96 Identities = 399/1631 (24%), Positives = 699/1631 (42%), Gaps = 140/1631 (8%) Query: 138 LPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196 L +P ++R+ A++ L + Y +D +G G + TP AKK+ L SQ++Y Sbjct: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-VWDTPQILHAKKSYDLQSQLQYTAA 4637 Query: 197 HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF--------------- 241 E + ++ V DTP + + S+V+Y E+Y Q + K + Sbjct: 4638 GKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKN 4697 Query: 242 ----------------PAMITPAYQI----AKRANELASDVRYHQQYQKEMRGMAGPAIG 281 + I P+ + AK LAS ++Y ++Y+K P Sbjct: 4698 LYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSV 4757 Query: 282 AEGILTRECAD----QYGQGYPEEYEEHRGK-GSFPAMITPAYQNAKKAHELASDIKYRQ 336 + T C + Y YE+++ K P M+ AK + + S+I YR Sbjct: 4758 DDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMV--TAKDSQKKVSEIDYRL 4815 Query: 337 DFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNV 396 ++ + D V + V +S++ YK DL +G +TP+ + Sbjct: 4816 RLHEW--------ICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHA 4867 Query: 397 SKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYN 456 D KYK + R Y+ V + A+K G S+ Y DY H + Sbjct: 4868 KHAYDLRDDIKYKA-HMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKV 4926 Query: 457 YPATLTPSYQTAMKLVPLKDAN-YRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYR 513 P T T A+ L+ +N Y+ S+ L Y DTP K S+ Y+ Sbjct: 4927 APTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYK 4986 Query: 514 ADYEKNK-LNYTL-PQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571 YE K YTL P+DVP + + N + SE Y+E + K K K D + Sbjct: 4987 EAYEHTKAYGYTLGPKDVPFVHVRRVN-NVTSERLYRELYHKLKDK-IHTTPDTPEIRQV 5044 Query: 572 KASGELASNIKYKEEYEKTKGKAMGTA-DSRLLHSLQIAKMSSEVEYKKGFEESK---TR 627 K + E S + YK ++ K +G + +++H + ++S+++YK+ + K Sbjct: 5045 KKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCF 5104 Query: 628 FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE-YTVL---PEDMKTQWAKKAYGLQSELQY 683 + DMV RH +K + D +K+ + Y V+ PE K Q K SEL Y Sbjct: 5105 LYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHL---SELVY 5161 Query: 684 KADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELK--FTSVTDSSQMEHAKK 741 +A K + + +L +AK+ +L S+ Y + + + + ++ ++HAK Sbjct: 5162 RAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKD 5221 Query: 742 SQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELR 801 +++ S YK E+ +YT D P+ ++A+ N S+ YK +++ K K ++ Sbjct: 5222 VKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVK 5281 Query: 802 LDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYK 861 D+L + + D S++KYKE+Y G + + + H ++ S+++YK Sbjct: 5282 -DALDIVYHRKVTDDISKIKYKENYMSQLGIW---RSIPDRPEHFHHRAVTDTVSDVKYK 5337 Query: 862 KGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKV-------EWA 914 + K + D A K + L + YK F +D K Sbjct: 5338 EDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEV---FERTKSDFKYVADSPINRHF 5394 Query: 915 KKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDAL--KFTS 972 K A L ++ +YRAD + K + AK AG+ IS+ KYR++ + KFTS Sbjct: 5395 KYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTS 5454 Query: 973 IKDTPEMVQARISYTQAVDRLYREQGENIK-HHYTPTADLPEVLLAKLNAMNISETRYKE 1031 I DTPE ++ Q D LY+ + K YT D P +L + +S+ +YKE Sbjct: 5455 IVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKE 5514 Query: 1032 SWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHS 1091 + + + DA+ +AAK + ++ ++ YK+ +E K + D + A S Sbjct: 5515 VYQR-NKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKS 5573 Query: 1092 VYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDY--KHPLPQYT--S 1147 + QSD YK E K D V A + + S+ Y KH + T + Sbjct: 5574 ---SLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHA 5630 Query: 1148 LAEDLRLSCAKKAHKLQSENLYRSDL--NFMRGVACVIPGTLEIEGRKKASELISESKYR 1205 + + ++ AK L SEN Y+ + + +G +P T + K+ ++ +S++ Y+ Sbjct: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690 Query: 1206 ----QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAK 1261 + Y+ + + P + HA + ++ Y+ ++ H YT P+ +A Sbjct: 5691 KKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLH-YTTVADRPDIKKAT 5749 Query: 1262 TNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIG 1321 A S+ Y+ R + G + + + A+ + ++S YR +F KE+GK Sbjct: 5750 QAAKQASEVEYRAKHRKEGSHGLSM-LGRPDIEMAKKAAKLSSQVKYRENFDKEKGK-TP 5807 Query: 1322 PQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPM----DMVHLVHAKNAQALAS 1377 + +D + + L SE++Y+ + + H P+ + + + H N LAS Sbjct: 5808 KYNPKDSQLYKVMKDANNLASEVKYK----ADLKKLHKPVTDMKESLIMNHVLNTSQLAS 5863 Query: 1378 DHDYRTQYHK----FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQME 1433 + Y+ +Y K + +P++L+ K+A LQS ++YK +G L +P Sbjct: 5864 SYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYI 5923 Query: 1434 SAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH 1489 +AK++ ++ S +YRK +SIK T + +P L+H K + +E+ YR ES+ Sbjct: 5924 TAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIR 5983 Query: 1490 --RYTLIPDHPDFTRARLNALHLSDKVYRNSWE-QTRAGSYDFRLDAIP-FQTARASREI 1545 T + D PD RA+ L++K Y+ E + + + + P F AR + +I Sbjct: 5984 GKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDI 6043 Query: 1546 ASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTD 1605 AS +YK++ ++ + SV D P + H V L S +YK+D KS S + + D Sbjct: 6044 ASQIKYKQSAEMEKA---NFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLD 6100 Query: 1606 QPGLLQAKRSQQLASDVHYRQPLPQP-------TCDPEQLGLRHAQKAHQLQSDVKYKSD 1658 P + + + +Q+ S + Y+ L PE L ++ QK S V YK D Sbjct: 6101 TPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNF---SSVLYKED 6157 Query: 1659 LNLTRGVGWTP 1669 ++ +G TP Sbjct: 6158 VSPGTAIGKTP 6168 Score = 336 bits (862), Expect = 1e-91 Identities = 386/1671 (23%), Positives = 688/1671 (41%), Gaps = 196/1671 (11%) Query: 141 PEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQ---RAKKANQLASQVEYKRGH 197 P++V MV A+ S + DY + + P Q +K S + YK Sbjct: 4793 PDMVEMVTAKDSQKKVSEIDYRLRLHEW----ICHPDLQVNDHVRKVTDQISDIVYKDDL 4848 Query: 198 DERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANE 257 + V DTPE+L +K L+ D++Y + R TP Y A ++ + Sbjct: 4849 NWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKL-VTDTPVYVQAVKSGK 4907 Query: 258 LASDVRYHQQYQKEMRGMAGPAIGAEGI------LTRECADQYGQGYPEEYEEHRGKGSF 311 SD YH Y +RG P + + ++ Y +R G Sbjct: 4908 QLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGD- 4966 Query: 312 PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371 TP +++ K ++S KY++ + K A+ ++L +D + + VN + SE Sbjct: 4967 ----TPHFKHIKDTRYMSSYFKYKEAYEHTK--AYGYTLGPKD-VPFVHVRRVNNVTSER 5019 Query: 372 EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431 Y++ + +TP+ R V K + S+ YK ++ M+G + + +H Sbjct: 5020 LYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFK-MQGHMISLPYTPQVIH 5078 Query: 432 AMKVGSLASNVAYKADYK------------HDIVDYNYPATLTPSYQTAMKLVPLKDANY 479 VG + S++ YK D + D+V + L +Y K ++D Sbjct: 5079 CRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRD--- 5135 Query: 480 RQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNA 539 KY V DTP+ + + LS + YRA +K K +T D P L++AK Sbjct: 5136 -------KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQ 5188 Query: 540 KLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTAD 599 KL S+ Y E K + +L AK ++ S KYK +YEK K K D Sbjct: 5189 KLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPD 5247 Query: 600 SRLLHSLQIAKMS-SEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK---- 654 + +L + A + S++ YK+ F+++K ++H D ++I + +K S + Y++ Sbjct: 5248 TPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMS 5307 Query: 655 KLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS 714 +L + +P+ + + S+++YK DL W+KG+G + + A+K L S Sbjct: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYS 5367 Query: 715 EKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFL 772 + Y++ + K F V DS H K + +L + Y+A EQ +Y + DEP L Sbjct: 5368 KYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHL 5427 Query: 773 QARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGK 832 A+ +S+ Y+ ++E K K F +D+ L S++ YK +Y +++ + Sbjct: 5428 LAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPR 5486 Query: 833 LIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATD 892 G + + H ++ S+L+YK+ ++ KS C + D VH+ A+ A + T+ Sbjct: 5487 --GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTN 5544 Query: 893 VGYKTA----EHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLN--- 945 + YK + H+ P A K+ QSD +Y+ D +++KG T N Sbjct: 5545 LDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVL 5604 Query: 946 --------------------------------VEQAKKAGELISEKKYRQHPDAL----K 969 + AK L+SE KY+ H Sbjct: 5605 ALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGS 5664 Query: 970 FTSIKDTPEMVQAR-----ISYTQAVDRLYREQGEN----------IKH----------- 1003 +T++ +T + V + +S T + +E+G++ +KH Sbjct: 5665 YTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDV 5724 Query: 1004 ----------HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALP-FQA 1052 HYT AD P++ A A SE Y+ K +G + L + P + Sbjct: 5725 AYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRK--EGSHGLSMLGRPDIEM 5782 Query: 1053 AKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKA 1112 AK + ++ S KY+E F+K KG+ + + A +L S+V YK + Sbjct: 5783 AKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKD-ANNLASEVKYKADLK---- 5837 Query: 1113 QFHLPL----DMAALVHAKKAQTLASNQDYKHPLPQ----YTSLAEDLRLSCAKKAHKLQ 1164 + H P+ + + H LAS+ YK + Y ++ ++L K+A +LQ Sbjct: 5838 KLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQ 5897 Query: 1165 SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ-HPHSFK---YTAVTDTP 1220 S Y+ RG + T K++ ++ S +YR+ + S K T + TP Sbjct: 5898 SIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTP 5957 Query: 1221 NLLHAKFSNQITNERLYKAAGEDARHEYTMTL--GLPEFIRAKTNAANLSDARYKESWR- 1277 LLH K++ +I +E+ Y+ E++ +T P+ +RAK L++ YK Sbjct: 5958 ALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLEL 6017 Query: 1278 NLRAQGYKLTIEALP-FQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRR 1336 ++ +G P F AR + DIAS Y+ E+ SV D P I H ++ Sbjct: 6018 EVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFT---SVVDTPEIIHAQQ 6074 Query: 1337 MGQLQSELQYRRGATSSQAQFHLPMDMVHLVHA----KNAQALASDHDYRTQYHKFTALP 1392 + L S+ +Y+ A S + + +D + KN L D + K T + Sbjct: 6075 VKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQ 6134 Query: 1393 EDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPD 1452 + ++ K+ S + YK D+ IG ++P+M K+ + IS KY++ Sbjct: 6135 DTPEILRVKENQKNFSSVLYKEDVSPGTAIG----KTPEMMRVKQTQDHISSVKYKEAIG 6190 Query: 1453 SIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSD 1512 + T + D P++ K + H + MY+ E+L P+ R + N + S Sbjct: 6191 --QGTPIPDLPEVKRVKETQKHISSVMYK----ENLGTGIPTTVTPEIERVKRNQENFSS 6244 Query: 1513 KVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDP 1572 +Y+ + + ++ + + ++E S YKE + L + P Sbjct: 6245 VLYKENLGKGIPTPITPEMERV-----KRNQENFSSVLYKENMGKGTPLAV-------TP 6292 Query: 1573 RMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPT 1632 M+ + S YK++ K+ + + P + + KR+Q+ S V Y++ L + T Sbjct: 6293 EMERVKHNQENISSVLYKENVGKATA----TPVTPEMQRVKRNQENISSVLYKENLGKAT 6348 Query: 1633 CDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1683 P + ++ + S V YK ++ TP ++E A+R E Sbjct: 6349 PTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTP----EMERAKRNQE 6395 Score = 295 bits (755), Expect = 3e-79 Identities = 377/1606 (23%), Positives = 660/1606 (41%), Gaps = 155/1606 (9%) Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234 TP ++ KK + S++ YK + ++ TP+++ + + SD++Y ED + Sbjct: 5038 TPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097 Query: 235 QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294 +G G F TP ++ +L S+ Y + +K MR + + + Sbjct: 5098 LKGFGCF-LYDTPDMVRSRHLRKLWSNYLYTDKARK-MRDKYKVVLDTPEYRKVQELKTH 5155 Query: 295 GQGYPEEYEEHRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353 + K F ++ TP AK+ +L S Y + K + H+H+ Sbjct: 5156 LSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKER--PHHHA--GN 5211 Query: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413 LK A+ V +VSE +YK E + +TP + SD +YKE +Q Sbjct: 5212 QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQ 5271 Query: 414 NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP 473 +G+Y V ++ KV S + YK +Y + + + Sbjct: 5272 K-TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDT 5330 Query: 474 LKDANYRQSIDKLKYSS--VTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQ 531 + D Y++ + LK DTP A+ N S Y+ +E+ K ++ D P Sbjct: 5331 VSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPI 5390 Query: 532 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591 K +L +E KY+ +E+ K K + + +D L AK +G+ S IKY++ YEK+K Sbjct: 5391 NRHFKYATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449 Query: 592 GKAMGTADS-RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPM-DMVNIRHAKKAQTLASD 649 K D+ L + ++ K S++ YK + ++K R + + D + H +K + SD Sbjct: 5450 DKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSD 5509 Query: 650 LDYR----KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQ 705 L Y+ + T+ P+ + + AK AY + + L YK K T + Q Sbjct: 5510 LKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQ 5569 Query: 706 AKKAGQLVSEKNYRQRVDELKFT--SVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYT 763 A K+ S+ Y+ + LK SVTD A ++ ++S + YK E+ V + Sbjct: 5570 AAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYK---EKHVKERG 5626 Query: 764 ISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 823 P D+ L AK +L SE KYK Sbjct: 5627 TCHAVP---------------------------------DTPQILLAKTVSNLVSENKYK 5653 Query: 824 EDYERSRGKLIGAKDVQGDSQMS-HSLQMSKLQSELEYKKGF--EDTKSQCHVSLDMVHL 880 + ++ + G+ +++ + H +++K S+ YKK F E KS + L+ + Sbjct: 5654 DHVKKHLAQ--GSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEV 5711 Query: 881 VHARKAQHLATDVGY-KTAEH--HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMG 937 HA + +DV Y K A+ H+T + ++ A +A S+ +YRA + G Sbjct: 5712 KHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHG 5771 Query: 938 WVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYRE- 996 G ++E AKKA +L S+ KYR++ D K + K P+ Q + + L E Sbjct: 5772 LSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQL-YKVMKDANNLASEV 5830 Query: 997 -QGENIKHHYTPTADLPEVLLAK--LNAMNISET-RYKESWSKLRDGGYKLRLDALPFQA 1052 ++K + P D+ E L+ LN ++ + +YK+ + K + G Y D L Sbjct: 5831 KYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSK-GHYHTIPDNLEQLH 5889 Query: 1053 AKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS-K 1111 K + E+ S KYKE +EK +G+ + I+ S +QS Y+K +E S K Sbjct: 5890 LKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKES---QQMQSGKEYRKDYEESIK 5946 Query: 1112 AQFHLPLDMA-ALVHAKKAQTLASNQDYKHPLPQ------YTSLAEDLRLSCAKKAHKLQ 1164 + L++ AL+H K A +AS ++Y+ L + T + + + AK A ++ Sbjct: 5947 GRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQIL 6006 Query: 1165 SENLYRSDLNFM---RGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDT 1219 +E Y+ DL RG+ + T + + A+++ S+ KY+Q K +T+V DT Sbjct: 6007 NEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDT 6066 Query: 1220 PNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNL 1279 P ++HA+ +++++ YK E + Y L PE R + N N S +Y+ +N Sbjct: 6067 PEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNS 6126 Query: 1280 RAQGYKLTI--EALPFQAARASGDIASDFLYRHDFVKERGKLIG--PQSVR--------- 1326 + K+T+ + + + S LY+ D G IG P+ +R Sbjct: 6127 KG---KITVVQDTPEILRVKENQKNFSSVLYKEDV--SPGTAIGKTPEMMRVKQTQDHIS 6181 Query: 1327 ---------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKN 1371 D P ++ + + S + Y+ + P + K Sbjct: 6182 SVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTP----EIERVKR 6237 Query: 1372 AQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1431 Q S Y+ K P +M K+ S + YK ++ G G +P+ Sbjct: 6238 NQENFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENM----GKGTPLAVTPE 6293 Query: 1432 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1491 ME K E IS Y++ T V +P++ K + + + +Y+ E+L + Sbjct: 6294 MERVKHNQENISSVLYKENVGKATATPV--TPEMQRVKRNQENISSVLYK----ENLGKA 6347 Query: 1492 TLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRY 1551 T P P+ R + N + S +Y+ + + ++ A+ ++E S Y Sbjct: 6348 TPTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPEMER-----AKRNQENISSVLY 6402 Query: 1552 KEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQ 1611 ++F + + Y V D P M+ R S +Y +DF K + F P + Sbjct: 6403 SDSFRKQIQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITER 6460 Query: 1612 AKRSQQLASDVHYR------QPLPQPTCDPEQ---LGLRHAQKAHQLQSDVKYKSDLNLT 1662 K++ Q SD++YR + Q D +Q GLR + D D + Sbjct: 6461 VKKNMQDFSDINYRGIQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQS 6520 Query: 1663 RGVGWTPPGSYKVEMARRAAELA-NARGLGLQGAYRGAEAVEAGDH 1707 R + V+ RR+ E + +A L + G +E EA DH Sbjct: 6521 RSL-----HMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDH 6561 Score = 264 bits (674), Expect = 6e-70 Identities = 281/1147 (24%), Positives = 488/1147 (42%), Gaps = 133/1147 (11%) Query: 155 EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214 ++Y DYEQ + K + P + AK A SQ++Y++ +++ +F+++VDTPE L Sbjct: 5404 KKYRADYEQRKDKYHL-VVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHL 5462 Query: 215 RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274 R+ + SD+ Y +Y + + +G TP ++ + SD++Y + YQ R Sbjct: 5463 RTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQ---RN 5519 Query: 275 MAGPAIGAEGILTRECADQY----GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELAS 330 + I + + + D Y Y ++YE ++ + P + A K+ S Sbjct: 5520 KSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKW-TPDRPDFLQAAKSSLQQS 5578 Query: 331 DIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCET 390 D +Y+ D +KG S+ N VL ++ + S+++YK+ RG +T Sbjct: 5579 DFEYKLDREFLKGCK--LSVTDDKNTVLALRNTL--IESDLKYKEKHVKERGTCHAVPDT 5634 Query: 391 PQFRNVSKISKFTSDNKYKENYQNHM-RGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK 449 PQ +S S+NKYK++ + H+ +G Y + R T+H +V S+ YK + Sbjct: 5635 PQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFV 5694 Query: 450 HDIVDYNYPATL-TPSYQTAMKLVPLK-DANYRQSI-DKLKYSSVTDTPQIVQAKINAQQ 506 + NY L P + AM++ + D YR+ + L Y++V D P I +A A+Q Sbjct: 5695 KEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQ 5754 Query: 507 LSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMK-LDA 565 S V YRA + K + P + AK AKL S+VKY+E ++K KGK + D+ Sbjct: 5755 ASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDS 5814 Query: 566 MSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLL-HSLQIAKMSSEVEYKKGFEES 624 K + LAS +KYK + +K +S ++ H L ++++S +YKK +E+S Sbjct: 5815 QLYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKS 5874 Query: 625 KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPE-DMKTQ---WAKKAYGLQSE 680 K +H D + H K+A L S + Y++K + P D +T AK++ +QS Sbjct: 5875 KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSG 5934 Query: 681 LQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 740 +Y+ K+Y + + T + + + H K Sbjct: 5935 KEYR-------------------------------KDYEESIKGRNLTGLEVTPALLHVK 5963 Query: 741 KSQELQSGVAYKAGNEQSVH--QYTISKDEPLFLQARANAANLSEKLYKSSWENQ-KAKG 797 + ++ S Y+ E+S+ T +D P L+A+ L+EK YK E + K +G Sbjct: 5964 YATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRG 6023 Query: 798 FE-LRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQS 856 + ++ F+ A+ D+AS++KYK+ E + D ++ H+ Q+ L S Sbjct: 6024 LNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDT---PEIIHAQQVKNLSS 6080 Query: 857 ELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKK 916 + +YK+ E + S LD + R+ Q +F+ L Sbjct: 6081 QKKYKEDAEKSMSYYETVLDTPEIQRVRENQ------------KNFSLL----------- 6117 Query: 917 AYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDT 976 QY+ D+K KG V + + + K+ + S Y++ D T+I T Sbjct: 6118 --------QYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKE--DVSPGTAIGKT 6167 Query: 977 PEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKL 1036 PEM++ + Q D + + + TP DLPEV K +IS YKE+ Sbjct: 6168 PEMMRVK----QTQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENL--- 6220 Query: 1037 RDGGYKLRLDALP-FQAAKASGEIISDYKYKEAFEK-----MKGQMLGSRSLEDDISLAH 1090 G + P + K + E S YKE K + +M + +++ Sbjct: 6221 ---GTGIPTTVTPEIERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQENF---- 6273 Query: 1091 SVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAE 1150 S V YK+ P + K Q S+ YK + + T+ Sbjct: 6274 --------SSVLYKENMGKGTPLAVTP----EMERVKHNQENISSVLYKENVGKATATPV 6321 Query: 1151 DLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHS 1210 + K+ + S LY+ +L G A P T E+E K+ E S Y+++ Sbjct: 6322 TPEMQRVKRNQENISSVLYKENL----GKATPTPFTPEMERVKRNQENFSSVLYKENMR- 6376 Query: 1211 FKYTAVTDTPNLLHAKFSNQITNERLYK-AAGEDARHEYTMTLGLPEFIRAKTNAANLSD 1269 K T TP + AK + + + LY + + + + L PE R + ++S Sbjct: 6377 -KATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHIST 6435 Query: 1270 ARYKESW 1276 +Y E + Sbjct: 6436 VKYHEDF 6442 Score = 82.8 bits (203), Expect = 3e-15 Identities = 114/487 (23%), Positives = 199/487 (40%), Gaps = 51/487 (10%) Query: 70 TPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANERAYWTGYGE 129 TP + R + S I ++ E K+ F + + + A + L++++ Y + Sbjct: 6031 TPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEK 6090 Query: 130 GNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLA 188 ++ L PEI R+ E +K+ +Y D + +GK + TP R K+ + Sbjct: 6091 SMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITV-VQDTPEILRVKENQKNF 6149 Query: 189 SQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248 S V YK E +S + + TPE++R K S V+Y E G+G+ P P Sbjct: 6150 SSVLYK----EDVSPGTAIGKTPEMMRVKQTQDHISSVKYKEAI----GQGT-PIPDLPE 6200 Query: 249 YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEE-YEEHRG 307 + K + S V Y KE G P I E + + + Y+E+ G Sbjct: 6201 VKRVKETQKHISSVMY-----KENLGTGIPTTVTPEI---ERVKRNQENFSSVLYKENLG 6252 Query: 308 KGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367 KG P ITP + K+ E S + Y+++ K P +++ + + Sbjct: 6253 KG-IPTPITPEMERVKRNQENFSSVLYKENMGK--------GTPLAVTPEMERVKHNQEN 6303 Query: 368 VSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427 +S V YK+++ + + TP+ + V + + S YKEN G+ Sbjct: 6304 ISSVLYKENVGKATATPV----TPEMQRVKRNQENISSVLYKENL-----GKATPTPFTP 6354 Query: 428 RTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMK------LVPLKDANYRQ 481 + S+V YK + + P +TP + A + V D+ +Q Sbjct: 6355 EMERVKRNQENFSSVLYKENMRKAT-----PTPVTPEMERAKRNQENISSVLYSDSFRKQ 6409 Query: 482 SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541 K Y V DTP++ + + + +S V Y D+EK+K +T P + K N + Sbjct: 6410 IQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQD 6467 Query: 542 FSEVKYK 548 FS++ Y+ Sbjct: 6468 FSDINYR 6474 >gi|169217576 PREDICTED: similar to nebulin [Homo sapiens] Length = 410 Score = 330 bits (846), Expect = 7e-90 Identities = 167/395 (42%), Positives = 250/395 (63%) Query: 772 LQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRG 831 LQA NA +S KLY+ W + K KG+++R D++ AKA R++ASE KYKE Y + G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 832 KLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLAT 891 +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ +V A+K Q L + Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 892 DVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKK 951 D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+ GS+ V + K Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 Query: 952 AGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADL 1011 A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + LYR E K + AD Sbjct: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 Query: 1012 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1071 P +L +K+NA+ IS RY+++W ++ GY LR DA+ Q AKAS +I SDY YK A+EK Sbjct: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 Query: 1072 MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQT 1131 KG +G RS ++D L + +Q+D YKK + KA+ +P+DM ++ AK+ Q Sbjct: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 Query: 1132 LASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1166 LAS+ DY+H L ++ + + A+KA+ LQS+ Sbjct: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 300 bits (767), Expect = 1e-80 Identities = 157/396 (39%), Positives = 241/396 (60%), Gaps = 4/396 (1%) Query: 532 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591 +++A NA S Y++ W TK KG++++ DA+ + AKAS E+AS KYKE Y K Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 592 GKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 647 G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I AKK Q L Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 648 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 707 SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL EGS+ + + K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 708 KAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 767 A L++E+ YR + + LKFTS+ D+ ++ AK + S Y+ E+ + D Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 768 EPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYE 827 PL LQ++ NA +S K Y+ +WE+ K G++LR D++ AKA RD+AS+ YK YE Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 828 RSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQ 887 + +G IG + + D ++ + + K+Q++ YKK + D K++ + +DMV + A++ Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 888 HLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSD 923 LA+DV Y+ HH++ P V A+KAY LQSD Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396 Score = 298 bits (764), Expect = 2e-80 Identities = 150/397 (37%), Positives = 247/397 (62%) Query: 1014 VLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK 1073 +L A +NA+ IS Y++ W+ + GY +R DA+ + AKAS EI S+YKYKE + K Sbjct: 1 MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60 Query: 1074 GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLA 1133 G +G R+L+DD +++A +QSD YKK +E SK + PLDM ++V AKK Q L Sbjct: 61 GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120 Query: 1134 SNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRK 1193 S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+ + G++E+ K Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180 Query: 1194 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1253 A L++E YR P + K+T++ DTP ++ AK + +E LY+ A E + + Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240 Query: 1254 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1313 P +++K NA +S+ RY+++W +++ GY L +A+ Q A+AS DIASD+LY+ + Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300 Query: 1314 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1373 K++G IG +S ++DP++ + ++Q++ Y++ +A+ +P+DMV + AK Q Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360 Query: 1374 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1410 ALASD DYR H ++ P+ + A+KA+ LQS++ Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 283 bits (724), Expect = 1e-75 Identities = 146/396 (36%), Positives = 241/396 (60%) Query: 1258 IRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERG 1317 ++A NA +S+ Y++ W + + +GY + +A+ + A+AS +IAS++ Y+ + K+ G Sbjct: 2 LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61 Query: 1318 KLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALAS 1377 +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+ +V AK Q L S Sbjct: 62 HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121 Query: 1378 DHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKK 1437 D DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL S ++ K Sbjct: 122 DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181 Query: 1438 AGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1497 A L++E YR KP+++KFT++VD+P+++ AK + + +E +YR+ + + D Sbjct: 182 AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241 Query: 1498 PDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLR 1557 P ++++NAL +S+K Y+ +WE + YD R DAI Q A+ASR+IASD+ YK A+ + Sbjct: 242 PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301 Query: 1558 DRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQ 1617 +G IG RS +DP++ NV ++Q+D YKK + +++ D + AK Q Sbjct: 302 QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361 Query: 1618 LASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1653 LASDV YR L +C P+Q + A+KA+ LQSDV Sbjct: 362 LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 191 bits (486), Expect = 4e-48 Identities = 125/390 (32%), Positives = 202/390 (51%), Gaps = 14/390 (3%) Query: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLV 357 Y +++ + + KG ++AK + E+AS+ KY++ + K G H QD+ Sbjct: 16 YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH-HMGFRTLQDDPK 74 Query: 358 LKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMR 417 A K+ S+ EYKK E S+G + K SD Y+ NY + Sbjct: 75 SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLH--- 130 Query: 418 GRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--HDIVDYNYPATLTPSYQTAMKLVPLK 475 ++ + + A K L S+ YK+D + I + + A L L Sbjct: 131 -QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNL--LN 187 Query: 476 DANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKA 535 + YR + LK++S+ DTP+++QAKINA Q+S YR +EK K N +P D P ++++ Sbjct: 188 ERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQS 247 Query: 536 KTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAM 595 K NA S +Y++ WE K G++++ DA+ + AKAS ++AS+ YK YEK KG + Sbjct: 248 KINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYI 307 Query: 596 G----TADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLD 651 G D +L+ + + KM ++ YKK + + K + +P+DMV+I AK+ Q LASD+D Sbjct: 308 GCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVD 367 Query: 652 YRKKLHEYTVLPEDMKTQWAKKAYGLQSEL 681 YR LH ++ P+ A+KAY LQS++ Sbjct: 368 YRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397 Score = 165 bits (418), Expect = 3e-40 Identities = 80/187 (42%), Positives = 119/187 (63%) Query: 1502 RARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGL 1561 +A +NAL +S+K+Y+ W T+ YD R DAI + A+ASREIAS+++YKE + + G Sbjct: 3 QAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH 62 Query: 1562 QIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASD 1621 +G+R++ DDP+ ++ ++QSD EYKK + KS+ ++ D ++QAK+ Q L SD Sbjct: 63 HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSD 122 Query: 1622 VHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1681 + YR L Q TC P+Q + A+KA+ LQSD YKSDL +G+GW P GS +V + A Sbjct: 123 IDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNA 182 Query: 1682 AELANAR 1688 L N R Sbjct: 183 QNLLNER 189 Score = 74.7 bits (182), Expect = 7e-13 Identities = 94/437 (21%), Positives = 183/437 (41%), Gaps = 92/437 (21%) Query: 157 YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISR---FSTVVDTPEL 213 Y +D+ + KG + AK + ++AS+ +YK G+ +++ F T+ D P+ Sbjct: 16 YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKS 75 Query: 214 LRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMR 273 + + A++QSD Y + YE+ +G + P + Q AK+ L SD+ Y + Y + Sbjct: 76 VWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVLVSDIDY-RNYLHQWT 133 Query: 274 GMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333 + P++ + AKKA++L SD Sbjct: 134 CL-----------------------PDQND---------------VIQAKKAYDLQSDNL 155 Query: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQF 393 Y+ D +KG LP + ++ + + ++ L++E Y+ E+ + SI +TP+ Sbjct: 156 YKSDLEWLKGIGW---LP-EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPE- 208 Query: 394 RNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV 453 + + ++A+++ S Y+ ++ + Sbjct: 209 -------------------------------VIQAKINAVQI----SEPLYRNAWEKEKA 233 Query: 454 DYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLK---YSSVTDTPQIVQAKINAQQLSHV 510 + N PA Q+ + + + + Y+Q+ + +K Y D I AK + S Sbjct: 234 NVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293 Query: 511 NYRADYEKNKLNY---TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMS 567 Y+ YEK K +Y ++ P+LV A K+ ++ YK+ + K K + +D +S Sbjct: 294 LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK-ISIPVDMVS 352 Query: 568 LLAAKASGELASNIKYK 584 + AAK LAS++ Y+ Sbjct: 353 ISAAKEGQALASDVDYR 369 Score = 72.0 bits (175), Expect = 5e-12 Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 57/339 (16%) Query: 1339 QLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK-------FTAL 1391 Q+ ++L + + Q + + D + + HAK ++ +AS++ Y+ Y K F L Sbjct: 10 QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69 Query: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKP 1451 +D K WA A +QS+ YK KGI L + AKK L+S+ YR Sbjct: 70 QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY- 128 Query: 1452 DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1511 LH++T +PD D +A+ S Sbjct: 129 ------------------------------------LHQWTCLPDQNDVIQAKKAYDLQS 152 Query: 1512 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1571 D +Y++ E + + +P + R + E R + + + S+ D Sbjct: 153 DNLYKSDLEWLKGIGW------LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDT 206 Query: 1572 PRMKHFLNVGRLQ-SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQ 1630 P + + +Q S+ Y+ + K ++ + D P +LQ+K + S+ Y+Q Sbjct: 207 PEVIQ-AKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWED 265 Query: 1631 PTCD-----PEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1664 + +G++HA+ + + SD YK+ +G Sbjct: 266 VKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304 Score = 52.8 bits (125), Expect = 3e-06 Identities = 67/278 (24%), Positives = 113/278 (40%), Gaps = 59/278 (21%) Query: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 LPD V ++A+K+ + Y D E +G G P R K A L ++ Y Sbjct: 135 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 191 Query: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITP------ 247 + + +F+++VDTPE++++K A S+ Y +E+++ + PA TP Sbjct: 192 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA-DTPLMLQSK 248 Query: 248 ------------------------------AYQIAKRANELASDVRYHQQYQKEMRGMAG 277 Q AK + ++ASD Y Y+K+ G Sbjct: 249 INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIG 308 Query: 278 PAIGAEGILTRECAD----QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333 E A+ Q + Y + Y +H+ K S P + + AK+ LASD+ Sbjct: 309 CRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV-SISAAKEGQALASDVD 367 Query: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371 YR + H+ P Q++++ QA+ L S+V Sbjct: 368 YRHYLH------HWSCFPDQNDVI--QARKAYDLQSDV 397 >gi|5453758 nebulette sarcomeric isoform [Homo sapiens] Length = 1014 Score = 194 bits (493), Expect = 6e-49 Identities = 198/822 (24%), Positives = 376/822 (45%), Gaps = 57/822 (6%) Query: 484 DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFS 543 D++ Y V + + A+ + +S + Y+ +++K+K T D P L K S Sbjct: 26 DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85 Query: 544 EVKYKEGWEKTKGKGFEMKLDAM--SLLAAKASGELASNIKYKEEYEKTKG---KAMGTA 598 E KYK + ++ A S+ A + + +L S + YK++++ KG A Sbjct: 86 EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVT-QLQSEVAYKQKHDAAKGFSDYAHMKE 144 Query: 599 DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK--- 655 + H++++ K S + Y+K +++ T + +D +I+ A + + S+ +Y+K Sbjct: 145 PPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQISKIISNAEYKKGQGI 203 Query: 656 LHEYTVLPEDMKTQWAKKAYGLQSELQYKADL---AWMKGVGWLTEGSLNLEQAKKAGQL 712 +++ + + A +A L S+++YK K + S + Q + A L Sbjct: 204 MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATL 263 Query: 713 VSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPL 770 S Y++ + + + + + ++H K+ ++ SG YK E++ Y D Sbjct: 264 ASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVE 323 Query: 771 FLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERS- 829 L + NA S+ YK +E K K +++ ++ A+K + + SE YKED+E+ Sbjct: 324 HLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEI 383 Query: 830 RGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED--TKSQCHVSLDMVHLVHARKAQ 887 +G+ + D+ + H ++ L E EYKK E+ ++ +++ + A++A Sbjct: 384 KGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRAS 441 Query: 888 HLATDVGYK------TAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKW-MKGMGW-V 939 +A++ YK A ++++ AKKA + S+ Y+ D++ +KG G V Sbjct: 442 EMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQV 501 Query: 940 ATGSLNVEQAKKAGELISEKKYRQH-PDALKFTSIK---DTPEMVQARISYTQAVDRLYR 995 +T +L+V++AKKA E+ S+K+Y++ + +K ++ D P++++A+ + R Y+ Sbjct: 502 STDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYK 561 Query: 996 EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1055 ++ E + +Y+ AD PE+ K NIS YK+ G D+ + K Sbjct: 562 DEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKK-----EVGAGTAVKDSPEIERVKK 616 Query: 1056 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1115 + + IS KYKE ++ + ++ D L S++ YK+ ++ KA Sbjct: 617 NQQNISSVKYKE-------EIKHATAISDPPELKRVKENQKNISNLQYKE--QNYKA--- 664 Query: 1116 LPLDMA-ALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN 1174 P+ M + ++ Q S YK L + T++++ L AK+ K S YR L Sbjct: 665 TPVSMTPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL- 723 Query: 1175 FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNLLHAK-FSNQI 1231 G A + T E+E KK E IS KY Q K + + DTP + H K N I Sbjct: 724 ---GRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHI 780 Query: 1232 TNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYK 1273 + + ++ + +T + P R + N +SDA YK Sbjct: 781 SMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 191 bits (484), Expect = 7e-48 Identities = 216/826 (26%), Positives = 357/826 (43%), Gaps = 97/826 (11%) Query: 351 PAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKE 410 P ++L ++ A+ +L+S++ YK++ + S+ ++P +V I F S+ KYK Sbjct: 32 PVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKG 91 Query: 411 NYQNHM-RGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV----DYNYPATLTPSY 465 + + Y+ + ++ A +V L S VAYK KHD DY + P Sbjct: 92 TIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYK--QKHDAAKGFSDYAHMKE-PPEV 148 Query: 466 QTAMKL-VPLKDANYRQSI-DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNY 523 + AM++ + +YR+ + D YS+ D P I A Q+S + A+Y+K + Sbjct: 149 KHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKM----ATQISKIISNAEYKKGQGIM 204 Query: 524 TLPQDV---PQLVKAKTNAKLFSEVKYKEGW--EKTKGKGFEMKLDAMSLLAAKASGELA 578 V P A +KL S++KYKE + E K L++ S + + LA Sbjct: 205 NKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLA 264 Query: 579 SNIKYKEEYEKTKGKAMGTADSRLL-HSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 637 SN+KYK++ + + L H L+ +KM S EYKK FEE+K +H D V Sbjct: 265 SNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEH 324 Query: 638 RHAKKAQTLASDLDYRKKLHEYTVLP-----EDMKTQWAKKAYGLQSELQYKADLA---- 688 H K L S + Y+++ + P E Q +K+A +QSE YK D Sbjct: 325 LHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIK 384 Query: 689 ----------------------------------WMKGVGW-LTEGSLNLEQAKKAGQLV 713 +KG G L L++++AK+A ++ Sbjct: 385 GRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMA 444 Query: 714 SEKNYRQRVDEL----KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV--HQYTISKD 767 SEK Y++ ++ + + TD+ +M+HAKK+ E+ S YK E + +S D Sbjct: 445 SEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTD 504 Query: 768 EPLFLQARANAANLSEKLYKSSWENQ-KAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 826 +A+ + S+K YK EN+ K KG ++ +D L AK ++ S+ KYK++ Sbjct: 505 TLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEA 564 Query: 827 ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 886 E+ D ++ + Q S + YKK + + V D + +K Sbjct: 565 EKMLSNYSTIADTPEIQRIKTTQQNI---SAVFYKK---EVGAGTAVK-DSPEIERVKKN 617 Query: 887 QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATG---S 943 Q + V YK H TA+ +++ K+ S+ QY K + AT + Sbjct: 618 QQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQY-------KEQNYKATPVSMT 670 Query: 944 LNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKH 1003 +E+ ++ E +S KY+ + + T+I D PE+ +A+ + + YR Q Sbjct: 671 PEIERVRRNQEQLSAVKYK--GELQRGTAISDPPELKRAKENQKNISNVYYRGQ----LG 724 Query: 1004 HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDY 1063 T + PE+ K N NIS +Y + +++ G L LD + K + IS Sbjct: 725 RATTLSVTPEMERVKKNQENISSVKYTQDHKQMK-GRPSLILDTPAMRHVKEAQNHISMV 783 Query: 1064 KYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1109 KY E FEK KG+ G + DD T + SD YK H Sbjct: 784 KYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 827 Score = 179 bits (453), Expect = 3e-44 Identities = 205/804 (25%), Positives = 351/804 (43%), Gaps = 118/804 (14%) Query: 322 AKKAHELASDIKYRQDFNKMK------------------GA-----------------AH 346 A+K EL SDI+Y+++F K K GA + Sbjct: 42 ARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSL 101 Query: 347 YHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHS--INYCETPQFRNVSKISKFTS 404 Y +PA + V A V +L SEV YK+ ++++G S + E P+ ++ +++K S Sbjct: 102 YKRMPATIDSVF--AGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQS 159 Query: 405 DNKYKENYQNH----------------------MRGRY-EGVGMDRRT---------LHA 432 + Y+++ Q+ Y +G G+ + HA Sbjct: 160 NISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHA 219 Query: 433 MKVGSLASNVAYKADYKHDIVD--YNYPATLTPSY-QTAMKLVPLKDANYRQSIDKLKYS 489 ++ L+S + YK + +++ D ++Y + S+ Q + + Y++ I + + Sbjct: 220 VEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNM-HD 278 Query: 490 SVTDTPQIV---QAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVK 546 V+D P ++ ++ LS Y+ +E+NK Y D + + K NA L S+VK Sbjct: 279 PVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVK 338 Query: 547 YKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEK-TKGKAMGTADS--RLL 603 YKE +EK KGK ++ S A+K + ++ S YKE++EK KG++ D L Sbjct: 339 YKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFL 398 Query: 604 HSLQIAKMSSEVEYKKGFE-ESKTR-FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE--- 658 H I + E EYKK E E K + L ++++I+ AK+A +AS+ +Y+K L Sbjct: 399 HVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIK 458 Query: 659 ---YTVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGW-LTEGSLNLEQAKKAGQLV 713 + ++ Q AKKA + SE YK DL +KG G ++ +L++++AKKA ++ Sbjct: 459 GKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMA 518 Query: 714 SEKNYRQRVD-ELKFTSV---TDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEP 769 S+K Y++ ++ E+K + D + AK++ E+ S YK E+ + Y+ D P Sbjct: 519 SQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTP 578 Query: 770 LFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERS 829 + + N+S YK + G ++ DS K + S VKYKE+ + Sbjct: 579 EIQRIKTTQQNISAVFYK----KEVGAGTAVK-DSPEIERVKKNQQNISSVKYKEEIKH- 632 Query: 830 RGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHL 889 A + ++ + K S L+YK E VS+ + R+ Q Sbjct: 633 ------ATAISDPPELKRVKENQKNISNLQYK---EQNYKATPVSM-TPEIERVRRNQEQ 682 Query: 890 ATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQA 949 + V YK TA+ +++ AK+ S+ YR + G + + +E+ Sbjct: 683 LSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL----GRATTLSVTPEMERV 738 Query: 950 KKAGELISEKKYRQHPDALKF--TSIKDTPEMVQARISYTQAVDRLYREQGENIK-HHYT 1006 KK E IS KY Q +K + I DTP M + + Y E E K +T Sbjct: 739 KKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFT 798 Query: 1007 PTADLPEVLLAKLNAMNISETRYK 1030 P D P + N +S+ YK Sbjct: 799 PVVDDPVTERVRKNTQVVSDAAYK 822 Score = 176 bits (447), Expect = 1e-43 Identities = 204/817 (24%), Positives = 349/817 (42%), Gaps = 78/817 (9%) Query: 723 DELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLS 782 D++ + V + ME A+K EL S + YK ++S + T D P+ + A +S Sbjct: 26 DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85 Query: 783 EKLYKSSWENQKAKGFELRLDS-LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQG 841 E YK + + + R+ + + + A L SEV YK+ ++ ++G ++ Sbjct: 86 EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKE 144 Query: 842 DSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHH 901 ++ H+++++K QS + Y+K +DT + LD + A + + ++ YK + Sbjct: 145 PPEVKHAMEVNKHQSNISYRKDVQDTHTYS-AELDRPDIKMATQISKIISNAEYKKGQGI 203 Query: 902 FTALPT-------DMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGE 954 P + VE +K + ++ ++ ++K K + S + Q + A Sbjct: 204 MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHH-YNPLESASFRQNQLAAT 262 Query: 955 LISEKKYRQHPDALKFTSIKDTPEMV---QARISYTQAVDRLYREQGENIKHHYTPTADL 1011 L S KY++ + + D P ++ + R Y++ E K Y AD Sbjct: 263 LASNVKYKKDIQNMH-DPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADA 321 Query: 1012 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1071 E L K NA+ S+ +YKE + K + ++ +QA+K + ++ S+ YKE FEK Sbjct: 322 VEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEK 381 Query: 1072 -MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL--VHAKK 1128 +KG+ S L+ H Y T+L + YKK E+ + L+ L AK+ Sbjct: 382 EIKGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKR 439 Query: 1129 AQTLASNQDYKHPLPQYT------SLAEDLRLSCAKKAHKLQSENLYRSDLNF-MRGVAC 1181 A +AS ++YK L + + L + AKKA ++ SE Y+ DL ++G Sbjct: 440 ASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGM 499 Query: 1182 -VIPGTLEIEGRKKASELISESKYRQH-PHSFKYTAVT---DTPNLLHAKFSNQITNERL 1236 V TL+++ KKASE+ S+ +Y++ + K + D P++L AK +++I ++R Sbjct: 500 QVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRK 559 Query: 1237 YKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALP-FQA 1295 YK E Y+ PE R KT N+S YK+ G ++ P + Sbjct: 560 YKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKE------VGAGTAVKDSPEIER 613 Query: 1296 ARASGDIASDFLYRHDF--------------VKERGKLIGPQSVRDD----------PRI 1331 + + S Y+ + VKE K I ++ P I Sbjct: 614 VKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEI 673 Query: 1332 QHCRRMGQLQSELQYR----RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK 1387 + RR + S ++Y+ RG S D L AK Q S+ YR Q + Sbjct: 674 ERVRRNQEQLSAVKYKGELQRGTAIS--------DPPELKRAKENQKNISNVYYRGQLGR 725 Query: 1388 FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKY 1447 T L +M KK S ++Y D MKG L L +P M K+A IS KY Sbjct: 726 ATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKY 785 Query: 1448 RKKPDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1481 + + K FT VVD P + + ++ Y+ Sbjct: 786 HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822 Score = 168 bits (425), Expect = 5e-41 Identities = 215/898 (23%), Positives = 380/898 (42%), Gaps = 116/898 (12%) Query: 138 LPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGH 197 +P E ++ + +GEE E+ +Q K P + + + A+K +L S + YK Sbjct: 3 VPVFEDIKDETEEEKIGEEENEE-DQVFYK---PVIEDLSMELARKCTELISDIRYKEEF 58 Query: 198 DERISRFSTVVDTPELLRSK-----------------------------------AG--A 220 + + + V D+P L K AG Sbjct: 59 KKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVT 118 Query: 221 QLQSDVRYTEDYEQQRGKGSFPAM-ITPAYQIAKRANELASDVRYHQQYQKEMRGMA--- 276 QLQS+V Y + ++ +G + M P + A N+ S++ Y + Q A Sbjct: 119 QLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELD 178 Query: 277 GPAIGAEGILTRECADQYGQGYPEEYEEHRG-KGSFPAMI-TPAYQNAKKAHELASDIKY 334 P I +++ ++ EY++ +G PA+I P +++A +A +L+S IKY Sbjct: 179 RPDIKMATQISKIISN-------AEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKY 231 Query: 335 RQDF-NKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQF 393 ++ F N+MK H+++ ++ +Q Q L S V+YKKD+++ + Sbjct: 232 KEKFDNEMKDKKHHYN--PLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFL 289 Query: 394 RNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV 453 +V K SK S +YK+ ++ + +G Y LH L S V YK +Y+ + Sbjct: 290 DHVLKASKMLSGREYKKLFEEN-KGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKG 348 Query: 454 DYNYPATLTPSYQTAMKLVPLKDAN-YRQSIDK-LKYSSVTD---TPQIVQAKINAQQLS 508 TPSYQ + + ++ Y++ +K +K S D TP+ + K L Sbjct: 349 KPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLR 408 Query: 509 HVNYRADYE---KNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEK-TKGKGFEMKLD 564 Y+ D E K K L +V + +AK +++ SE +YK+ E KGKG + D Sbjct: 409 EKEYKKDLENEIKGK-GMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTD 467 Query: 565 AMSLLAAKASGELASNIKYKEEYE---KTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGF 621 + + AK + E+AS YK + E K KG + T + + + ++M+S+ +YKK Sbjct: 468 TLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDL 527 Query: 622 E-ESKTR-FHLPMDMVNIRHAKKAQTLASDLDYR----KKLHEYTVLPEDMKTQWAKKAY 675 E E K + + MD+ +I AK+ + S Y+ K L Y+ + + + Q K Sbjct: 528 ENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQ 587 Query: 676 GLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQ 735 S + YK ++ G G + S +E+ KK Q +S Y++ + T+++D + Sbjct: 588 QNISAVFYKKEV----GAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHA--TAISDPPE 641 Query: 736 MEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKA 795 ++ K++Q+ S + YK N ++ T P + R N LS YK + A Sbjct: 642 LKRVKENQKNISNLQYKEQN----YKATPVSMTPEIERVRRNQEQLSAVKYKGELQRGTA 697 Query: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855 D AK + S V Y RG+L A + +M + + Sbjct: 698 IS-----DPPELKRAKENQKNISNVYY-------RGQLGRATTLSVTPEMERVKKNQENI 745 Query: 856 SELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGY-----KTAEHHFTALPTDMK 910 S ++Y + + K + + LD + H ++AQ+ + V Y KT FT + D Sbjct: 746 SSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPV 805 Query: 911 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDAL 968 E +K + SD Y+ + VE ++ G ++ K +R P ++ Sbjct: 806 TERVRKNTQVVSDAAYKGVHPHI------------VEMDRRPGIIVDLKVWRTDPGSI 851 Score = 160 bits (406), Expect = 8e-39 Identities = 195/804 (24%), Positives = 338/804 (42%), Gaps = 82/804 (10%) Query: 908 DMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDA 967 D+ +E A+K L SD +Y+ + K K T S + K G ISE KY+ A Sbjct: 36 DLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKA 95 Query: 968 -LKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-------YTPTADLPEVLLAKL 1019 L + K P + + + V +L E KH Y + PEV Sbjct: 96 DLSNSLYKRMPATIDS--VFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVK---- 149 Query: 1020 NAMNISETRYKESWSK-LRDGG-YKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQML 1077 +AM +++ + S+ K ++D Y LD + A +IIS+ +YK K +G M Sbjct: 150 HAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYK----KGQGIMN 205 Query: 1078 GSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS---KAQFHLPLDMAALVHAKKAQTLAS 1134 ++ H+V A+ L S + YK+ F++ K + PL+ A+ + A TLAS Sbjct: 206 KEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLAS 265 Query: 1135 NQDYKHPLPQYTSLAEDLR----LSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIE 1190 N YK + DL L KA K+ S Y+ +G+ +E Sbjct: 266 NVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHL 325 Query: 1191 GRKKASELISESKYRQHPHSFKYTAV---TDTPNLLHAKFSNQITNERLYKAAGEDARHE 1247 K + L S+ KY++ K + +TP+ +K + ++ +E++YK ED E Sbjct: 326 HHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYK---EDFEKE 382 Query: 1248 YTMTLGL-----PEFIRAKTNAANLSDARYKESWRN-LRAQGYKLTIEALPFQAARASGD 1301 L PEF+ K L + YK+ N ++ +G +L E L Q A+ + + Sbjct: 383 IKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASE 442 Query: 1302 IASDFLYRHDFVKE-RGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS--QAQFH 1358 +AS+ Y+ D +GK G Q+ D +QH ++ ++ SE Y+R + Sbjct: 443 MASEKEYKKDLESIIKGK--GMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQ 500 Query: 1359 LPMDMVHLVHAKNAQALASDHDYRTQYHKFTA---------LPEDLKMAWAKKAHALQSE 1409 + D + + AK A +AS Y+ +P+ L+ AK+ + S+ Sbjct: 501 VSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILR---AKRTSEIYSQ 557 Query: 1410 LRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAK 1469 +YK + M +P+++ K + IS Y+K+ + T V DSP++ K Sbjct: 558 RKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGA--GTAVKDSPEIERVK 615 Query: 1470 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1529 + + + Y+ E + T I D P+ R + N ++S+ Y+ + S Sbjct: 616 KNQQNISSVKYK----EEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTP 671 Query: 1530 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589 ++ + R ++E S +YK R ++ D P +K + S+ Y Sbjct: 672 EIERV-----RRNQEQLSAVKYKGELQRGT-------AISDPPELKRAKENQKNISNVYY 719 Query: 1590 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQL----GLRHAQK 1645 + ++ + + P + + K++Q+ S V Y Q Q P + +RH ++ Sbjct: 720 RGQLGRATTL----SVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKE 775 Query: 1646 AHQLQSDVKYKSDLNLTRGVGWTP 1669 A S VKY D T+G G+TP Sbjct: 776 AQNHISMVKYHEDFEKTKGRGFTP 799 Score = 142 bits (358), Expect = 3e-33 Identities = 170/740 (22%), Positives = 310/740 (41%), Gaps = 83/740 (11%) Query: 991 DRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPF 1050 +++ E+ E + Y P + + LA+ IS+ RYKE + K +D D+ Sbjct: 16 EKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDK-CTFVTDSPML 74 Query: 1051 QAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS 1110 K G IS+ KYK + L R + I + T LQS+V YK+ + + Sbjct: 75 NHVKNIGAFISEAKYKGTIKADLSNSLYKR-MPATIDSVFAGEVTQLQSEVAYKQKHDAA 133 Query: 1111 K--AQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLR---LSCAKKAHKLQS 1165 K + + + + HA + SN Y+ + + + +L + A + K+ S Sbjct: 134 KGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIIS 193 Query: 1166 ENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ----------------HPH 1209 Y+ M VI G + E +AS+L S+ KY++ Sbjct: 194 NAEYKKGQGIMNKEPAVI-GRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESA 252 Query: 1210 SFK---------------------YTAVTDTPNLL---HAKFSNQITNERLYKAAGEDAR 1245 SF+ + V+D PNLL H ++++ + R YK E+ + Sbjct: 253 SFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENK 312 Query: 1246 HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASD 1305 Y E + K NA S +YKE + + + +E +QA++ + + S+ Sbjct: 313 GMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSE 372 Query: 1306 FLYRHDFVKERGKLIGPQSVRDD--PRIQHCRRMGQLQSELQYRRGATS--SQAQFHLPM 1361 +Y+ DF KE + G S+ D P H + + L E +Y++ + L Sbjct: 373 KVYKEDFEKE---IKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNS 429 Query: 1362 DMVHLVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQSELRYKSD 1415 +++ + AK A +AS+ +Y+ A + L+M AKKA + SE YK D Sbjct: 430 EVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRD 489 Query: 1416 L-IGMKGIGW-LALRSPQMESAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAK 1469 L +KG G ++ + ++ AKKA E+ S+ +Y+K + IK +D PD++ AK Sbjct: 490 LETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAK 549 Query: 1470 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1529 + ++R Y+ + L Y+ I D P+ R + ++S Y+ G+ Sbjct: 550 RTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKK-----EVGAGTA 604 Query: 1530 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589 D+ + + +++ S +YKE ++ D P +K + S+ +Y Sbjct: 605 VKDSPEIERVKKNQQNISSVKYKEEIKH-------ATAISDPPELKRVKENQKNISNLQY 657 Query: 1590 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQL 1649 K+ K+ + P + + +R+Q+ S V Y+ L + T + L+ A++ + Sbjct: 658 KEQNYKAT----PVSMTPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKN 713 Query: 1650 QSDVKYKSDLNLTRGVGWTP 1669 S+V Y+ L + TP Sbjct: 714 ISNVYYRGQLGRATTLSVTP 733 >gi|239752495 PREDICTED: similar to nebulin [Homo sapiens] Length = 237 Score = 159 bits (401), Expect = 3e-38 Identities = 77/184 (41%), Positives = 118/184 (64%) Query: 821 KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 880 KYKE Y + G +G + +Q D + ++ +K+QS+ EYKK +E +K + LDM+ + Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 881 VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 940 V A+K Q L +D+ Y+ H +T LP V AKKAY LQSDN Y++D++W+KG+GW+ Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143 Query: 941 TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 1000 GS+ V + K A L++E+ YR P+ALKFTSI DTPE++QA+I+ Q + N Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFN 203 Query: 1001 IKHH 1004 ++H+ Sbjct: 204 VRHY 207 Score = 145 bits (365), Expect = 4e-34 Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 4/163 (2%) Query: 582 KYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 637 KYKE Y K G MG D + + ++ AK+ S+ EYKK +E+SK + P+DM++I Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 638 RHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLT 697 AKK Q L SD+DYR LH++T LP+ AKKAY LQS+ YK+DL W+KG+GWL Sbjct: 84 VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143 Query: 698 EGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 740 EGS+ + + K A L++E+ YR + + LKFTS+ D+ ++ AK Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAK 186 Score = 142 bits (359), Expect = 2e-33 Identities = 69/169 (40%), Positives = 108/169 (63%) Query: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119 + YKYKE + K G +G R+L+DD +++A +QSD YKK +E SK + PLD Sbjct: 20 VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79 Query: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179 M ++V AKK Q L S+ DY++ L Q+T L + + AKKA+ LQS+NLY+SDL +++G+ Sbjct: 80 MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139 Query: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFS 1228 + G++E+ K A L++E YR P + K+T++ DTP ++ AK + Sbjct: 140 GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKIN 188 Score = 130 bits (327), Expect = 1e-29 Identities = 67/186 (36%), Positives = 115/186 (61%), Gaps = 1/186 (0%) Query: 1306 FLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVH 1365 + Y+ + K+ G +G ++++DDP+ ++QS+ +Y++ S+ + P+DM+ Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 1366 LVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWL 1425 +V AK Q L SD DYR H++T LP+ + AKKA+ LQS+ YKSDL +KGIGWL Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142 Query: 1426 ALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA 1485 S ++ K A L++E YR KP+++KFT++VD+P+++ AK + + +E + +S D Sbjct: 143 PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE-VEKSRDN 201 Query: 1486 ESLHRY 1491 ++ Y Sbjct: 202 FNVRHY 207 Score = 118 bits (296), Expect = 4e-26 Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 12/163 (7%) Query: 1526 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1585 +YD L +P ++YKE + + G +G+R++ DDP+ ++ ++QS Sbjct: 12 TYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQS 59 Query: 1586 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1645 D EYKK + KS+ ++ D ++QAK+ Q L SD+ YR L Q TC P+Q + A+K Sbjct: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKK 119 Query: 1646 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1688 A+ LQSD YKSDL +G+GW P GS +V + A L N R Sbjct: 120 AYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNER 162 Score = 53.9 bits (128), Expect = 1e-06 Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 10/185 (5%) Query: 333 KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQ 392 KY++ + K G H QD+ A K+ S+ EYKK E S+G + Sbjct: 24 KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 393 FRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--H 450 K SD Y+ NY + ++ + + A K L S+ YK+D + Sbjct: 83 IVQAKKCQVLVSDIDYR-NYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137 Query: 451 DIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHV 510 I + + A L L + YR + LK++S+ DTP+++QAKINA Q+S V Sbjct: 138 GIGWLPEGSVEVMRVKNAQNL--LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195 Query: 511 NYRAD 515 D Sbjct: 196 EKSRD 200 Score = 40.4 bits (93), Expect = 0.015 Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%) Query: 464 SYQTAMKLVP---LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520 +Y ++ VP K+ +Q + + ++ D P+ V A A+ S Y+ YEK+K Sbjct: 12 TYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK 71 Query: 521 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580 + P D+ +V+AK L S++ Y+ + + D ++ AK + +L S+ Sbjct: 72 GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSD 126 Query: 581 IKYKEEYEKTKG 592 YK + E KG Sbjct: 127 NLYKSDLEWLKG 138 Score = 39.3 bits (90), Expect = 0.034 Identities = 44/175 (25%), Positives = 69/175 (39%), Gaps = 41/175 (23%) Query: 652 YRKKLHE---YTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 708 YRK+L + L +D K+ WA A +QS+ +YK KG+ Sbjct: 29 YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI--------------- 73 Query: 709 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 768 + D + AKK Q L S + Y+ +HQ+T D+ Sbjct: 74 ------------------HNTPLDMMSIVQAKKCQVLVSDIDYR----NYLHQWTCLPDQ 111 Query: 769 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 823 +QA+ S+ LYKS E K G+ L S+ + K ++L +E Y+ Sbjct: 112 NDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165 Score = 38.9 bits (89), Expect = 0.044 Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 45/242 (18%) Query: 1184 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1243 P T ++ + S E +Q H + + D P + A + +I ++R YK A E Sbjct: 10 PHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 69 Query: 1244 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1303 ++ + L + ++AK +SD Y RN Q L + QA +A D+ Sbjct: 70 SKGIHNTPLDMMSIVQAKKCQVLVSDIDY----RNYLHQWTCLPDQNDVIQAKKAY-DLQ 124 Query: 1304 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1363 SD LY+ S+L++ +G LP Sbjct: 125 SDNLYK--------------------------------SDLEWLKGIG------WLPEGS 146 Query: 1364 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1421 V ++ KNAQ L ++ YR + KFT++ + ++ AK SE+ D ++ Sbjct: 147 VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206 Query: 1422 IG 1423 G Sbjct: 207 YG 208 Score = 37.7 bits (86), Expect = 0.098 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 39/176 (22%) Query: 407 KYKENYQNHMRGRYEGVGM---DRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTP 463 KYKE Y+ + G + G D +++ A+ + S+ YK Y+ +N P + Sbjct: 24 KYKEGYRKQL-GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 464 SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE------ 517 Q V + D +YR + + ++ + D ++QAK S Y++D E Sbjct: 83 IVQAKKCQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140 Query: 518 ---------------KNKLN------------YTLPQDVPQLVKAKTNAKLFSEVK 546 +N LN +T D P++++AK NA SEV+ Sbjct: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196 Score = 37.7 bits (86), Expect = 0.098 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 4/76 (5%) Query: 192 EYKRGHDERISR---FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248 +YK G+ +++ F T+ D P+ + + A++QSD Y + YE+ +G + P + Sbjct: 24 KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83 Query: 249 YQIAKRANELASDVRY 264 Q AK+ L SD+ Y Sbjct: 84 VQ-AKKCQVLVSDIDY 98 Score = 37.0 bits (84), Expect = 0.17 Identities = 36/149 (24%), Positives = 52/149 (34%), Gaps = 44/149 (29%) Query: 1379 HDYRTQYHK-------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1431 + Y+ Y K F L +D K WA A +QS+ YK KGI L Sbjct: 23 YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82 Query: 1432 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1491 + AKK L+S+ YR LH++ Sbjct: 83 IVQAKKCQVLVSDIDYRNY-------------------------------------LHQW 105 Query: 1492 TLIPDHPDFTRARLNALHLSDKVYRNSWE 1520 T +PD D +A+ SD +Y++ E Sbjct: 106 TCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134 Score = 36.2 bits (82), Expect = 0.28 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 9/90 (10%) Query: 293 QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA 352 Q + Y + YE+ +G + P + Q AKK L SDI YR ++ + LP Sbjct: 58 QSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVLVSDIDYRNYLHQ------WTCLPD 110 Query: 353 QDNLVLKQAQSVNKLVSEVEYKKDLESSRG 382 Q++++ QA+ L S+ YK DLE +G Sbjct: 111 QNDVI--QAKKAYDLQSDNLYKSDLEWLKG 138 Score = 35.4 bits (80), Expect = 0.49 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 9/108 (8%) Query: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193 LPD V ++A+K+ + Y D E +G G P R K A L ++ Y Sbjct: 108 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 164 Query: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF 241 + + +F+++VDTPE++++K A S+V + D R GS+ Sbjct: 165 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210 Score = 31.2 bits (69), Expect = 9.1 Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 9/119 (7%) Query: 476 DANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLN-YTLPQDVPQL 532 D Y+++ +K K +++ D IVQAK +S ++YR N L+ +T D + Sbjct: 60 DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDV 114 Query: 533 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591 ++AK L S+ YK E KG G+ + ++ ++ K + L + Y+ + E K Sbjct: 115 IQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK 172 >gi|47087157 nebulette non-muscle isoform [Homo sapiens] Length = 270 Score = 125 bits (313), Expect = 5e-28 Identities = 70/198 (35%), Positives = 103/198 (52%), Gaps = 37/198 (18%) Query: 1 MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60 MN Q C+RCG VYP EK++C+D+ WHK CFHCEVCKM L++NN+ ++KKPYC+AH PK Sbjct: 1 MNPQ-CARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPK 59 Query: 61 NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120 +FT+V TP NL ++ E S + + D E+ K Sbjct: 60 -QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK------------------------ 94 Query: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQ 179 G G + PE+ R+ ++ + +Y ED+E+ +G+G P + P + Sbjct: 95 -------GRGFSI---VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTE 144 Query: 180 RAKKANQLASQVEYKRGH 197 R +K Q+ S YK H Sbjct: 145 RVRKNTQVVSDAAYKGVH 162 Score = 70.1 bits (170), Expect = 2e-11 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 1/125 (0%) Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233 TP R K+ ++L SQV+YKR +E R FS V DTPEL R K + S+V+Y ED+E Sbjct: 68 TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127 Query: 234 QQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQ 293 + +G+G P + P + ++ ++ SD Y + + P I +L Sbjct: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQS 187 Query: 294 YGQGY 298 + QGY Sbjct: 188 HSQGY 192 Score = 65.9 bits (159), Expect = 3e-10 Identities = 49/154 (31%), Positives = 75/154 (48%), Gaps = 10/154 (6%) Query: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263 F+TV DTPE LR K ++LQS V+Y D+E+ +G+G TP Q KR E S+V+ Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 264 YHQQYQK-EMRGMA----GPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSFPAMITP 317 YH+ ++K + RG P T+ +D +G +P E R G A + P Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLP 181 Query: 318 -AYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL 350 AYQ ++H ++ + M+ H +L Sbjct: 182 GAYQ---QSHSQGYGYMHQTSVSSMRSMQHSPNL 212 Score = 65.5 bits (158), Expect = 4e-10 Identities = 35/91 (38%), Positives = 54/91 (59%), Gaps = 9/91 (9%) Query: 511 NYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMK 562 NY+ YEK K ++T D P+ ++ K ++L S+VKYK +E++KG+GF + Sbjct: 43 NYKG-YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101 Query: 563 LDAMSLLAAKASGELASNIKYKEEYEKTKGK 593 D L K + E SN+KY E++EKTKG+ Sbjct: 102 TDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132 Score = 62.4 bits (150), Expect = 4e-09 Identities = 32/101 (31%), Positives = 58/101 (57%), Gaps = 1/101 (0%) Query: 485 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 543 K +++V DTP+ ++ K ++ S V Y+ D+E++K +++ D P+L + K + S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 544 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 584 VKY E +EKTKG+GF +D + + ++ S+ YK Sbjct: 119 NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 50.8 bits (120), Expect = 1e-05 Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 2/108 (1%) Query: 1002 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061 K +T AD PE L K + S+ +YK + + + G+ + D Q K + E IS Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1109 + KY E FEK KG+ G + DD T + SD YK H Sbjct: 119 NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164 Score = 47.0 bits (110), Expect = 2e-04 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 12/163 (7%) Query: 698 EGSLNLEQAKKAGQLVSEKNYRQR------VDELKFTSVTDSSQMEHAKKSQELQSGVAY 751 +G + E K A + + K Y ++ + FT+V D+ + K+ ELQS V Y Sbjct: 27 KGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKY 86 Query: 752 KAGNEQSVHQ-YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 810 K E+S + ++I D P + + +S Y +E K +GF +D Sbjct: 87 KRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERV 146 Query: 811 KAKRDLASEVKYKEDYER-----SRGKLIGAKDVQGDSQMSHS 848 + + S+ YK + R +I A + G Q SHS Sbjct: 147 RKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHS 189 Score = 46.2 bits (108), Expect = 3e-04 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 7/117 (5%) Query: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 PE +R+ + + + +Y D+E+ +G+G TP QR K+ + S V+Y ++ Sbjct: 69 PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEK 128 Query: 200 RISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDY----EQQRGKGSFPAMITP-AYQ 250 R F+ VVD P R + Q+ SD Y + E R G A + P AYQ Sbjct: 129 TKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQ 185 Score = 45.8 bits (107), Expect = 4e-04 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 2/103 (1%) Query: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304 + +T PE +R K + S +YK + + +G+ + + Q + + + S Sbjct: 59 KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118 Query: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1347 + Y DF K +G+ P V DDP + R+ Q+ S+ Y+ Sbjct: 119 NVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYK 159 Score = 45.4 bits (106), Expect = 5e-04 Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 32/165 (19%) Query: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 666 ++ KM+ + KG+E+ N + K++ T +D PE++ Sbjct: 33 EVCKMALNMNNYKGYEKKP--------YCNAHYPKQSFTTVADT------------PENL 72 Query: 667 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725 + K+ LQS+++YK D KG G+ + + L++ K+ + +S Y + ++ Sbjct: 73 RL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129 Query: 726 K---FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 767 K FT V D E +K+ ++ S AYK VH + + D Sbjct: 130 KGRGFTPVVDDPVTERVRKNTQVVSDAAYK-----GVHPHIVEMD 169 Score = 45.4 bits (106), Expect = 5e-04 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 4/98 (4%) Query: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYC-ETPQFRNVSKISKFTSDNKYKENY 412 +NL LKQ ++L S+V+YK+D E S+G + +TP+ + + + + S+ KY E++ Sbjct: 70 ENLRLKQQ---SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126 Query: 413 QNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH 450 + + V D T K + S+ AYK + H Sbjct: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164 Score = 44.3 bits (103), Expect = 0.001 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%) Query: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821 +T D P L+ + + S+ YK +E K +GF + D+ K ++ S VK Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 822 YKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYK 861 Y ED+E+++G+ G V D + +++ S+ YK Sbjct: 122 YHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 43.5 bits (101), Expect = 0.002 Identities = 28/132 (21%), Positives = 57/132 (43%), Gaps = 7/132 (5%) Query: 1185 GTLEIEGRKKASELISESKYRQHPH------SFKYTAVTDTPNLLHAKFSNQITNERLYK 1238 G E K A + + Y + P+ +T V DTP L K +++ ++ YK Sbjct: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87 Query: 1239 AAGEDAR-HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAAR 1297 E+++ +++ PE R K +S+ +Y E + + +G+ ++ + R Sbjct: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147 Query: 1298 ASGDIASDFLYR 1309 + + SD Y+ Sbjct: 148 KNTQVVSDAAYK 159 Score = 43.5 bits (101), Expect = 0.002 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%) Query: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1450 PE+L++ K+ LQS+++YK D KG G+ + +P+++ K+ E IS KY + Sbjct: 69 PENLRL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125 Query: 1451 PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1481 + K FT VVD P + + ++ Y+ Sbjct: 126 FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 Score = 42.7 bits (99), Expect = 0.003 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 6/109 (5%) Query: 557 KGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG--TADSRLLHSLQIAKMSSE 614 + F D L K EL S +KYK ++E++KG+ T L + + S Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119 Query: 615 VEYKKGFEESKTRFHLPM--DMVNIRHAKKAQTLASDLDYRKKLHEYTV 661 V+Y + FE++K R P+ D V R K Q + SD Y K +H + V Sbjct: 120 VKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQ-VVSDAAY-KGVHPHIV 166 Score = 42.4 bits (98), Expect = 0.004 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 7/132 (5%) Query: 942 GSLNVEQAKKAGELISEKKYRQHP------DALKFTSIKDTPEMVQARI-SYTQAVDRLY 994 G + E K A + + K Y + P FT++ DTPE ++ + S Q+ + Sbjct: 28 GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87 Query: 995 REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1054 R+ E+ ++ D PE+ K IS +Y E + K + G+ +D + + Sbjct: 88 RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147 Query: 1055 ASGEIISDYKYK 1066 + +++SD YK Sbjct: 148 KNTQVVSDAAYK 159 Score = 42.4 bits (98), Expect = 0.004 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 25/166 (15%) Query: 607 QIAKMSSEVEYKKGFEESKTR-FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE-----YT 660 Q +++ S+V+YK+ FEESK R F + D ++ K+ Q S++ Y + + +T Sbjct: 76 QQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135 Query: 661 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS------ 714 + +D T+ +K + S+ YK + +E ++ G +V+ Sbjct: 136 PVVDDPVTERVRKNTQVVSDAAYKGVHPHI------------VEMDRRPGIIVAPVLPGA 183 Query: 715 -EKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 759 ++++ Q + TSV+ M+H+ + ++ Y A +E V Sbjct: 184 YQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEV 229 Score = 42.0 bits (97), Expect = 0.005 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 7/127 (5%) Query: 1433 ESAKKAGELISETKYRKKP------DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAE 1486 E K A + + Y KKP FTTV D+P+ + K ++ Y+ E Sbjct: 33 EVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE 92 Query: 1487 SLHR-YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREI 1545 S R ++++ D P+ R + +S+ Y +E+T+ + +D + R + ++ Sbjct: 93 SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV 152 Query: 1546 ASDFRYK 1552 SD YK Sbjct: 153 VSDAAYK 159 Score = 41.2 bits (95), Expect = 0.009 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%) Query: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855 + F D+ L K + +L S+VKYK D+E S+G+ G V ++ + + Sbjct: 60 QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117 Query: 856 SELEYKKGFEDTKSQCHVS-LDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905 S ++Y + FE TK + +D RK + +D YK H + Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEM 168 Score = 40.8 bits (94), Expect = 0.012 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 18/126 (14%) Query: 1565 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1623 + +V D P LQS +YK+DF +S+ + F TD P L + KR+Q+ S+V Sbjct: 62 FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121 Query: 1624 YRQPLPQ-------PTCDPEQLGLRHAQKAHQLQSDVKYKS------DLNLTRGVGWTP- 1669 Y + + P D +K Q+ SD YK +++ G+ P Sbjct: 122 YHEDFEKTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPV 179 Query: 1670 -PGSYK 1674 PG+Y+ Sbjct: 180 LPGAYQ 185 Score = 37.4 bits (85), Expect = 0.13 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%) Query: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHS 1602 E+ S +YK F +G G+ V D P ++ S+ +Y +DF K++ + F Sbjct: 79 ELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTP 136 Query: 1603 STDQPGLLQAKRSQQLASDVHYR 1625 D P + +++ Q+ SD Y+ Sbjct: 137 VVDDPVTERVRKNTQVVSDAAYK 159 Score = 33.9 bits (76), Expect = 1.4 Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 21/160 (13%) Query: 1095 TSLQSDVNYKKGFEHSKAQ-FHLPLDMAALVHAKKAQTLASNQDYKHPLPQ-----YTSL 1148 + LQS V YK+ FE SK + F + D L K+ Q SN Y + +T + Sbjct: 78 SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137 Query: 1149 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKK--ASELISESKYRQ 1206 +D +K ++ S+ Y+ V P +E++ R + ++ + + Sbjct: 138 VDDPVTERVRKNTQVVSDAAYKG----------VHPHIVEMDRRPGIIVAPVLPGAYQQS 187 Query: 1207 HPHSFKYTAVTDTPNLLHAKFSNQITNERL---YKAAGED 1243 H + Y T ++ + S + R Y A ED Sbjct: 188 HSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDED 227 Score = 32.7 bits (73), Expect = 3.1 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 6/96 (6%) Query: 1324 SVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ-FHLPMDMVHLVHAKNAQALASDHDYR 1382 +V D P ++ +LQS+++Y+R S+ + F + D L K Q S+ Y Sbjct: 64 TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123 Query: 1383 TQYHK-----FTALPEDLKMAWAKKAHALQSELRYK 1413 + K FT + +D +K + S+ YK Sbjct: 124 EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159 >gi|5453710 LIM and SH3 protein 1 [Homo sapiens] Length = 261 Score = 105 bits (263), Expect = 3e-22 Identities = 46/91 (50%), Positives = 64/91 (70%), Gaps = 1/91 (1%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65 C+RCG VYP EK++C+D+ WHKACFHCE CKM L++ N+ ++KKPYC+AH PK +FT Sbjct: 5 CARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFT 63 Query: 66 SVYHTPLNLNVRTFPEAISGIHDQEDGEQCK 96 V TP NL ++ E S + +E+ E+ K Sbjct: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNK 94 Score = 70.1 bits (170), Expect = 2e-11 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%) Query: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263 F+ V DTPE LR K ++LQS VRY E++E+ +GKG TP Q K+ + S+++ Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 264 YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYP---EEYEEHRGKGSFPAMITPAYQ 320 YH++++K G + G EG+ Q G Y E+ + H S P P Q Sbjct: 122 YHEEFEKSRMGPS----GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQ 177 Query: 321 NAKKAH 326 +++ Sbjct: 178 PVAQSY 183 Score = 64.3 bits (155), Expect = 1e-09 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 9/93 (9%) Query: 507 LSHVNYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKG 558 L+ NY+ YEK K ++T+ D P+ ++ K ++L S+V+YKE +EK KGKG Sbjct: 39 LNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG 97 Query: 559 FEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591 F + D L K + + SNIKY EE+EK++ Sbjct: 98 FSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 51.2 bits (121), Expect = 9e-06 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 9/140 (6%) Query: 1002 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061 K +T AD PE L K + S+ RYKE + K + G+ + D Q K + + IS Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1121 + KY E FEK + G +E + Q +Y++ E + H+P Sbjct: 119 NIKYHEEFEKSRMGPSGGEGMEPE--------RRDSQDGSSYRRPLEQQQPH-HIPTSAP 169 Query: 1122 ALVHAKKAQTLASNQDYKHP 1141 ++ S YK P Sbjct: 170 VYQQPQQQPVAQSYGGYKEP 189 Score = 48.5 bits (114), Expect = 6e-05 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 6/82 (7%) Query: 485 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 543 K ++ V DTP+ ++ K ++ S V Y+ ++EKNK +++ D P+L + K S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 544 EVKYKEGWEKTK-----GKGFE 560 +KY E +EK++ G+G E Sbjct: 119 NIKYHEEFEKSRMGPSGGEGME 140 Score = 46.2 bits (108), Expect = 3e-04 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%) Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233 TP R K+ ++L SQV YK ++ + FS V DTPEL R K S+++Y E++E Sbjct: 68 TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127 Query: 234 QQR 236 + R Sbjct: 128 KSR 130 Score = 43.5 bits (101), Expect = 0.002 Identities = 22/69 (31%), Positives = 36/69 (52%) Query: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821 +T+ D P L+ + + S+ YK +E K KGF + D+ K +D S +K Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 822 YKEDYERSR 830 Y E++E+SR Sbjct: 122 YHEEFEKSR 130 Score = 43.1 bits (100), Expect = 0.002 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%) Query: 540 KLFSEVKYKEGWEKTK-------GKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 592 K+ +K +G+EK + F M D L K EL S ++YKEE+EK KG Sbjct: 36 KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95 Query: 593 KAMG-TADSRLLHSLQIAK-MSSEVEYKKGFEESK 625 K AD+ L ++ + S ++Y + FE+S+ Sbjct: 96 KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 41.2 bits (95), Expect = 0.009 Identities = 18/45 (40%), Positives = 27/45 (60%) Query: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMK 342 Y EE+E+++GKG TP Q KK + S+IKY ++F K + Sbjct: 86 YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130 Score = 40.8 bits (94), Expect = 0.012 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%) Query: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304 + +TM PE +R K + S RYKE + + +G+ + + Q + + D S Sbjct: 59 KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118 Query: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1360 + Y +F K R G + + + R Q YRR Q H+P Sbjct: 119 NIKYHEEFEKSRMGPSGGEGMEPERR--------DSQDGSSYRR-PLEQQQPHHIP 165 Score = 40.8 bits (94), Expect = 0.012 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 4/74 (5%) Query: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINY-CETPQFRNVSKISKFTSDNKYKENY 412 +NL LKQ ++L S+V YK++ E ++G + +TP+ + + K S+ KY E + Sbjct: 70 ENLRLKQQ---SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126 Query: 413 QNHMRGRYEGVGMD 426 + G G GM+ Sbjct: 127 EKSRMGPSGGEGME 140 Score = 36.6 bits (83), Expect = 0.22 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%) Query: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603 E+ S RYKE F +++G G+ V D P ++ S+ +Y ++F KSR Sbjct: 79 ELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM---GP 133 Query: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQ 1630 + G+ +R Q S YR+PL Q Sbjct: 134 SGGEGMEPERRDSQDGSS--YRRPLEQ 158 Score = 35.8 bits (81), Expect = 0.37 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 4/78 (5%) Query: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363 H K SF + TP K+ EL S ++Y+++F K KG S+ A D L++ + Sbjct: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG--FSVVA-DTPELQRIKK 112 Query: 364 VNKLVSEVEYKKDLESSR 381 +S ++Y ++ E SR Sbjct: 113 TQDQISNIKYHEEFEKSR 130 Score = 35.4 bits (80), Expect = 0.49 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 4/60 (6%) Query: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1450 PE+L++ K+ LQS++RYK + KG G+ + +P+++ KK + IS KY ++ Sbjct: 69 PENLRL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125 Score = 34.3 bits (77), Expect = 1.1 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 2/73 (2%) Query: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855 + F + D+ L K + +L S+V+YKE++E+++GK G V ++ + Sbjct: 60 QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117 Query: 856 SELEYKKGFEDTK 868 S ++Y + FE ++ Sbjct: 118 SNIKYHEEFEKSR 130 Score = 33.9 bits (76), Expect = 1.4 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 1/77 (1%) Query: 964 HPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-YTPTADLPEVLLAKLNAM 1022 H FT + DTPE ++ + Y+E+ E K ++ AD PE+ K Sbjct: 56 HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115 Query: 1023 NISETRYKESWSKLRDG 1039 IS +Y E + K R G Sbjct: 116 QISNIKYHEEFEKSRMG 132 Score = 33.5 bits (75), Expect = 1.8 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 1565 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1623 + V D P LQS YK++F K++ + F D P L + K++Q S++ Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 1624 YRQPLPQPTCDP 1635 Y + + P Sbjct: 122 YHEEFEKSRMGP 133 Score = 32.7 bits (73), Expect = 3.1 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199 PE +R+ + + + Y E++E+ +GKG TP QR KK S ++Y H+E Sbjct: 69 PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HEE 125 Score = 31.6 bits (70), Expect = 7.0 Identities = 38/182 (20%), Positives = 77/182 (42%), Gaps = 28/182 (15%) Query: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 666 + KM+ ++ KG+E+ N + K++ T+ +D PE++ Sbjct: 33 ETCKMTLNMKNYKGYEKKP--------YCNAHYPKQSFTMVADT------------PENL 72 Query: 667 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725 + K+ LQS+++YK + KG G+ + + L++ KK +S Y + ++ Sbjct: 73 RL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129 Query: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785 + + ME ++ + Q G +Y+ EQ + I P++ Q + S Sbjct: 130 RM-GPSGGEGMEPERR--DSQDGSSYRRPLEQQ-QPHHIPTSAPVYQQPQQQPVAQSYGG 185 Query: 786 YK 787 YK Sbjct: 186 YK 187 Score = 31.6 bits (70), Expect = 7.0 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 1213 YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHE-YTMTLGLPEFIRAKTNAANLSDAR 1271 +T V DTP L K +++ ++ YK E + + +++ PE R K +S+ + Sbjct: 62 FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121 Query: 1272 YKESWRNLR 1280 Y E + R Sbjct: 122 YHEEFEKSR 130 >gi|116517305 cysteine-rich protein 3 [Homo sapiens] Length = 204 Score = 54.3 bits (129), Expect = 1e-06 Identities = 21/50 (42%), Positives = 28/50 (56%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C RC V+ AEK+S + + WH+ C CE C +LS H +PYCH Sbjct: 5 CPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCH 54 Score = 51.2 bits (121), Expect = 9e-06 Identities = 19/50 (38%), Positives = 26/50 (52%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C CG VY AEK+ + + WH+ C C+ C L+ + H PYCH Sbjct: 124 CPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCH 173 >gi|4503049 cysteine-rich protein 2 [Homo sapiens] Length = 208 Score = 53.9 bits (128), Expect = 1e-06 Identities = 21/50 (42%), Positives = 27/50 (54%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C +C VY AEK+S + + WHK C CE C L+ H KP+CH Sbjct: 5 CPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCH 54 Score = 53.1 bits (126), Expect = 2e-06 Identities = 20/50 (40%), Positives = 27/50 (54%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C RC VY AEK++ + + WH+ C CE C L+ H +PYCH Sbjct: 126 CPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCH 175 >gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens] Length = 194 Score = 50.8 bits (120), Expect = 1e-05 Identities = 22/58 (37%), Positives = 27/58 (46%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 + C RCG VY AEK+ + WHK CF C +C L N + YC KN Sbjct: 118 EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKN 175 Score = 49.7 bits (117), Expect = 2e-05 Identities = 19/49 (38%), Positives = 26/49 (53%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE+I C + +HK CFHC C+ L +H+ + YC Sbjct: 10 CGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC 58 >gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens] Length = 194 Score = 50.8 bits (120), Expect = 1e-05 Identities = 22/58 (37%), Positives = 27/58 (46%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 + C RCG VY AEK+ + WHK CF C +C L N + YC KN Sbjct: 118 EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKN 175 Score = 49.7 bits (117), Expect = 2e-05 Identities = 19/49 (38%), Positives = 26/49 (53%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE+I C + +HK CFHC C+ L +H+ + YC Sbjct: 10 CGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC 58 >gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens] Length = 77 Score = 50.4 bits (119), Expect = 1e-05 Identities = 18/50 (36%), Positives = 28/50 (56%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55 C +C VY AE+++ + + WH+ C CE C L+ H+ KPYC+ Sbjct: 4 CPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCN 53 >gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens] Length = 193 Score = 49.7 bits (117), Expect = 2e-05 Identities = 23/58 (39%), Positives = 27/58 (46%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 + CSRCG VY AEKI + WHK CF C C L + + YC KN Sbjct: 117 EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174 Score = 46.6 bits (109), Expect = 2e-04 Identities = 18/49 (36%), Positives = 26/49 (53%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C CG VY AE++ C + +H+ CF C VC+ L H ++ YC Sbjct: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC 58 >gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo sapiens] Length = 193 Score = 46.6 bits (109), Expect = 2e-04 Identities = 21/56 (37%), Positives = 24/56 (42%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61 C RC VY AEK+ + WHKACF C C L + YC KN Sbjct: 119 CPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKN 174 Score = 43.5 bits (101), Expect = 0.002 Identities = 19/49 (38%), Positives = 25/49 (51%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE++ C +HK+CF C VCK L H ++ YC Sbjct: 10 CGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC 58 >gi|165905591 LIM domain and actin binding 1 isoform c [Homo sapiens] Length = 600 Score = 46.2 bits (108), Expect = 3e-04 Identities = 18/54 (33%), Positives = 27/54 (50%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C C VYP E++ Q++H +CF C C LS+ + S + YC H Sbjct: 229 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 282 >gi|165905589 LIM domain and actin binding 1 isoform a [Homo sapiens] Length = 760 Score = 46.2 bits (108), Expect = 3e-04 Identities = 18/54 (33%), Positives = 27/54 (50%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C C VYP E++ Q++H +CF C C LS+ + S + YC H Sbjct: 389 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 442 >gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens] Length = 759 Score = 46.2 bits (108), Expect = 3e-04 Identities = 18/54 (33%), Positives = 27/54 (50%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C C VYP E++ Q++H +CF C C LS+ + S + YC H Sbjct: 388 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 441 >gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Homo sapiens] Length = 938 Score = 45.1 bits (105), Expect = 6e-04 Identities = 20/52 (38%), Positives = 26/52 (50%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 C C VYP E + Q +HK+CF C C LS+ N+ S + YC H Sbjct: 402 CILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPH 453 >gi|7662330 actin binding LIM protein family, member 3 [Homo sapiens] Length = 683 Score = 43.9 bits (102), Expect = 0.001 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 11/80 (13%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65 C+ C + + + +D+ WH +CF C+ C ++L+ ++S PYC Sbjct: 151 CAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILT-GEYISKDGVPYCE---------- 199 Query: 66 SVYHTPLNLNVRTFPEAISG 85 S YH + T ISG Sbjct: 200 SDYHAQFGIKCETCDRYISG 219 >gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo sapiens] Length = 140 Score = 43.5 bits (101), Expect = 0.002 Identities = 19/49 (38%), Positives = 25/49 (51%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C C VY AE++ C +HK+CF C VCK L H ++ YC Sbjct: 10 CGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC 58 >gi|13386490 LIM domain containing 2 [Homo sapiens] Length = 127 Score = 42.4 bits (98), Expect = 0.004 Identities = 17/54 (31%), Positives = 29/54 (53%) Query: 4 QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57 + C+ C VYP E++ I+H +CF C+ C LS+ ++ + + YC H Sbjct: 38 ETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAALHGEFYCKPH 91 >gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209 >gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209 >gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] Length = 309 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 272 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 302 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 179 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 191 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 238 >gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] Length = 296 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 166 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 178 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225 >gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] Length = 280 Score = 42.0 bits (97), Expect = 0.005 Identities = 15/31 (48%), Positives = 20/31 (64%) Query: 24 QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 Q WH CFHC+ C + L+ FV HQ++ YC Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273 Score = 33.5 bits (75), Expect = 1.8 Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 25 IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 +WHK CF C CK ++ +F + YC Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150 Score = 33.1 bits (74), Expect = 2.4 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 6 CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54 C +C + + I+ DQ WH CF C C L+ F + + + YC Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209 >gi|194272207 actin binding LIM protein family, member 2 isoform 7 [Homo sapiens] Length = 470 Score = 42.0 bits (97), Expect = 0.005 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 3 VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56 ++ C CG + + + +D+ WH CF C+ C +L+ ++S PYC A Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202 >gi|153792514 actin binding LIM protein family, member 2 isoform 6 [Homo sapiens] Length = 521 Score = 42.0 bits (97), Expect = 0.005 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 3 VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56 ++ C CG + + + +D+ WH CF C+ C +L+ ++S PYC A Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202 >gi|194272204 actin binding LIM protein family, member 2 isoform 5 [Homo sapiens] Length = 531 Score = 42.0 bits (97), Expect = 0.005 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 3 VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56 ++ C CG + + + +D+ WH CF C+ C +L+ ++S PYC A Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.129 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,130,600 Number of Sequences: 37866 Number of extensions: 2734076 Number of successful extensions: 10161 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 66 Number of HSP's that attempted gapping in prelim test: 6941 Number of HSP's gapped (non-prelim): 506 length of query: 1730 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1614 effective length of database: 13,855,062 effective search space: 22362070068 effective search space used: 22362070068 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.