Guide to the Human Genome
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Search of human proteins with 46049105

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46049105 nebulin-related anchoring protein isoform S [Homo
sapiens]
         (1730 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46049105 nebulin-related anchoring protein isoform S [Homo sa...  3494   0.0  
gi|46049092 nebulin-related anchoring protein isoform C [Homo sa...  2782   0.0  
gi|115527120 nebulin [Homo sapiens]                                  1189   0.0  
gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]             330   7e-90
gi|5453758 nebulette sarcomeric isoform [Homo sapiens]                194   6e-49
gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]             159   3e-38
gi|47087157 nebulette non-muscle isoform [Homo sapiens]               125   5e-28
gi|5453710 LIM and SH3 protein 1 [Homo sapiens]                       105   3e-22
gi|116517305 cysteine-rich protein 3 [Homo sapiens]                    54   1e-06
gi|4503049 cysteine-rich protein 2 [Homo sapiens]                      54   1e-06
gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens]        51   1e-05
gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens]          51   1e-05
gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens]         50   1e-05
gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens]          50   2e-05
gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo s...    47   2e-04
gi|165905591 LIM domain and actin binding 1 isoform c [Homo sapi...    46   3e-04
gi|165905589 LIM domain and actin binding 1 isoform a [Homo sapi...    46   3e-04
gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens]     46   3e-04
gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Ho...    45   6e-04
gi|7662330 actin binding LIM protein family, member 3 [Homo sapi...    44   0.001
gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo...    44   0.002
gi|13386490 LIM domain containing 2 [Homo sapiens]                     42   0.004
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]    42   0.005
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]    42   0.005
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]    42   0.005
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]    42   0.005
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]     42   0.005
gi|194272207 actin binding LIM protein family, member 2 isoform ...    42   0.005
gi|153792514 actin binding LIM protein family, member 2 isoform ...    42   0.005
gi|194272204 actin binding LIM protein family, member 2 isoform ...    42   0.005

>gi|46049105 nebulin-related anchoring protein isoform S [Homo
            sapiens]
          Length = 1730

 Score = 3494 bits (9059), Expect = 0.0
 Identities = 1730/1730 (100%), Positives = 1730/1730 (100%)

Query: 1    MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60
            MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK
Sbjct: 1    MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60

Query: 61   NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120
            NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE
Sbjct: 61   NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120

Query: 121  RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180
            RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR
Sbjct: 121  RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180

Query: 181  AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240
            AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS
Sbjct: 181  AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240

Query: 241  FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300
            FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE
Sbjct: 241  FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPE 300

Query: 301  EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360
            EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ
Sbjct: 301  EYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQ 360

Query: 361  AQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRY 420
            AQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRY
Sbjct: 361  AQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRY 420

Query: 421  EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 480
            EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR
Sbjct: 421  EGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYR 480

Query: 481  QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 540
            QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK
Sbjct: 481  QSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAK 540

Query: 541  LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS 600
            LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS
Sbjct: 541  LFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADS 600

Query: 601  RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT 660
            RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT
Sbjct: 601  RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYT 660

Query: 661  VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ 720
            VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ
Sbjct: 661  VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQ 720

Query: 721  RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 780
            RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN
Sbjct: 721  RVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAAN 780

Query: 781  LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 840
            LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ
Sbjct: 781  LSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQ 840

Query: 841  GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 900
            GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH
Sbjct: 841  GDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEH 900

Query: 901  HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK 960
            HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK
Sbjct: 901  HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKK 960

Query: 961  YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN 1020
            YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN
Sbjct: 961  YRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLN 1020

Query: 1021 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR 1080
            AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR
Sbjct: 1021 AMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSR 1080

Query: 1081 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH 1140
            SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH
Sbjct: 1081 SLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKH 1140

Query: 1141 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS 1200
            PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS
Sbjct: 1141 PLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELIS 1200

Query: 1201 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1260
            ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA
Sbjct: 1201 ESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRA 1260

Query: 1261 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1320
            KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI
Sbjct: 1261 KTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLI 1320

Query: 1321 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1380
            GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD
Sbjct: 1321 GPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHD 1380

Query: 1381 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1440
            YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE
Sbjct: 1381 YRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGE 1440

Query: 1441 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1500
            LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF
Sbjct: 1441 LISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDF 1500

Query: 1501 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560
            TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG
Sbjct: 1501 TRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRG 1560

Query: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620
            LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS
Sbjct: 1561 LQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLAS 1620

Query: 1621 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1680
            DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR
Sbjct: 1621 DVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARR 1680

Query: 1681 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL 1730
            AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL
Sbjct: 1681 AAELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILHVKKKKALLL 1730


>gi|46049092 nebulin-related anchoring protein isoform C [Homo
            sapiens]
          Length = 1695

 Score = 2782 bits (7212), Expect = 0.0
 Identities = 1416/1586 (89%), Positives = 1458/1586 (91%), Gaps = 37/1586 (2%)

Query: 181  AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGS 240
            A     LA++  Y  G+ E  +     +  PE++R    A+      YTEDYEQ RGKGS
Sbjct: 111  APNRQPLANERAYWTGYGEGNAWCPGALPDPEIVRM-VEARKSLGEEYTEDYEQPRGKGS 169

Query: 241  FPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECAD-QYGQGYP 299
            FPAMITPAYQ AK+AN+LAS V Y + + + +   +      E + ++  A  Q    Y 
Sbjct: 170  FPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYT 229

Query: 300  EEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNK-MKGAA------------- 345
            E+YE+ RGKGSFPAMITPAYQ AK+A+ELASD++Y Q + K M+G A             
Sbjct: 230  EDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRE 289

Query: 346  -----------HYH------SLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRG----HS 384
                        Y       S PA      + A+  ++L S+++Y++D    +G    HS
Sbjct: 290  CADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHS 349

Query: 385  INYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAY 444
            +   +    +    ++K  S+NKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAY
Sbjct: 350  LPAQDNLVLKQAQSVNKLVSENKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAY 409

Query: 445  KADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINA 504
            KADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINA
Sbjct: 410  KADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINA 469

Query: 505  QQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLD 564
            QQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLD
Sbjct: 470  QQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLD 529

Query: 565  AMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEES 624
            AMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEES
Sbjct: 530  AMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEES 589

Query: 625  KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYK 684
            KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYK
Sbjct: 590  KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYK 649

Query: 685  ADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQE 744
            ADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQE
Sbjct: 650  ADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQE 709

Query: 745  LQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS 804
            LQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS
Sbjct: 710  LQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDS 769

Query: 805  LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF 864
            LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF
Sbjct: 770  LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGF 829

Query: 865  EDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDN 924
            EDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDN
Sbjct: 830  EDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDN 889

Query: 925  QYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARI 984
            QYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARI
Sbjct: 890  QYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARI 949

Query: 985  SYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR 1044
            SYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR
Sbjct: 950  SYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLR 1009

Query: 1045 LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK 1104
            LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK
Sbjct: 1010 LDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYK 1069

Query: 1105 KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQ 1164
            KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQ
Sbjct: 1070 KGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQ 1129

Query: 1165 SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLH 1224
            SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLH
Sbjct: 1130 SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLH 1189

Query: 1225 AKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGY 1284
            AKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGY
Sbjct: 1190 AKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGY 1249

Query: 1285 KLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSEL 1344
            KLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSEL
Sbjct: 1250 KLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSEL 1309

Query: 1345 QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH 1404
            QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH
Sbjct: 1310 QYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAH 1369

Query: 1405 ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD 1464
            ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD
Sbjct: 1370 ALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPD 1429

Query: 1465 LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA 1524
            LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA
Sbjct: 1430 LVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRA 1489

Query: 1525 GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1584
            GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ
Sbjct: 1490 GSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQ 1549

Query: 1585 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQ 1644
            SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQ
Sbjct: 1550 SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQ 1609

Query: 1645 KAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEA 1704
            KAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEA
Sbjct: 1610 KAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEA 1669

Query: 1705 GDHQSGEVNPDATEILHVKKKKALLL 1730
            GDHQSGEVNPDATEILHVKKKKALLL
Sbjct: 1670 GDHQSGEVNPDATEILHVKKKKALLL 1695


>gi|115527120 nebulin [Homo sapiens]
          Length = 6669

 Score = 1189 bits (3075), Expect = 0.0
 Identities = 619/1546 (40%), Positives = 974/1546 (63%), Gaps = 55/1546 (3%)

Query: 155  EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214
            + Y  +YE+ RGKG FP  IT  Y+  KK +Q      YK   D+  ++F+ V D+P LL
Sbjct: 456  KNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQCKDHT-YKVHPDK--TKFTQVTDSPVLL 512

Query: 215  RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274
            +++  ++  SD+ Y   +E ++ K   P   TPA+   K      SD  Y Q ++K    
Sbjct: 513  QAQVNSKQLSDLNYKAKHESEKFKCHIPPD-TPAFIQHKVNAYNLSDNLYKQDWEKSKAK 571

Query: 275  MAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKY 334
                 + A  +L                                   AK   +  SD+ Y
Sbjct: 572  KFDIKVDAIPLLA----------------------------------AKANTKNTSDVMY 597

Query: 335  RQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFR 394
            ++D+ K KG      L   D+  +  +  V K  S+  YK++ E ++  S+NYCETP+++
Sbjct: 598  KKDYEKNKGKM-IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQ 656

Query: 395  NVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVD 454
              +++  F S+ +YK+ Y   + G Y G   D    H MKV +  S+ +YKA+Y+ D   
Sbjct: 657  LDTQLKNF-SEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGK 715

Query: 455  YNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRA 514
              +P T+T  Y+   KL   KD  Y+   DK K+++VTD+P ++QA++N +QLS +NY+A
Sbjct: 716  CYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKA 775

Query: 515  DYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKAS 574
             +E  K    +P D PQ ++ + NA   S+  YK+ WEK+K K F++K+DA+ LLAAKA+
Sbjct: 776  KHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKAN 835

Query: 575  GELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHL 630
             +  S++ YK++YEK+KGK +G      D ++LHSL+ AK  S+ EY+K +E+SKT +  
Sbjct: 836  TKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTA 895

Query: 631  PMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL-AW 689
            P+DM+ +  AKK+Q +ASD+DY+  LH Y+  P+ +    AKKAY LQS+++YKAD  +W
Sbjct: 896  PLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSW 955

Query: 690  MKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGV 749
            MKG GW+  GSL +E+AK+A  +++EK YRQ  D LKFTS+ D+     +K +Q  +S +
Sbjct: 956  MKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDI 1015

Query: 750  AYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLA 809
            AYKA  E+ +H+Y +  D P F+QA+ NA N+SE +YK+  ++   KG++LR D++   A
Sbjct: 1016 AYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRA 1075

Query: 810  AKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKS 869
            AKA R  AS+V+YK+DYE+++GK++G + +Q D ++ H + ++K+QS+ EYKK +E TKS
Sbjct: 1076 AKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKS 1135

Query: 870  QCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRAD 929
            + +   DM ++V A+KAQ + ++V YK + HH+T LP  M +E +K    +QSDN Y+ D
Sbjct: 1136 KYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKED 1195

Query: 930  VK-WMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQ 988
               WMKG+GW+  GSL+VE+ KKAG+ ++EKKYRQHPD LKFTSI D+P MVQA+ +  Q
Sbjct: 1196 YNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQ 1255

Query: 989  AVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDAL 1048
              D LY+ +GE++KH YT + DLP+ L AK NA NIS+  YK  W  L   G  +  DA+
Sbjct: 1256 VSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAI 1315

Query: 1049 PFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFE 1108
            P  AAKAS  I SDYKYKEA+EK KG+ +G RSL+DD  L H +    LQSD  YKK +E
Sbjct: 1316 PITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYE 1375

Query: 1109 HSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL 1168
            ++K  +H P DM ++  AK AQ +A+N +YK PL  YT L + + L   +  +++QS+N+
Sbjct: 1376 NTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNV 1435

Query: 1169 YRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKF 1227
            Y+ + N F++G+  +  G+LE+E  KKA + ++E KYRQHP + K+T+V D+  ++ A+ 
Sbjct: 1436 YKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQH 1495

Query: 1228 SNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLT 1287
            + +  ++  YK  GE  +H+YT+   LP+FI+AK NA N+SDA YK  W+   A+GY L 
Sbjct: 1496 NTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLR 1555

Query: 1288 IEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1347
             +A+P  AA++S +IASD  Y+  + K +GK +G  S++DDP++ H   + ++QS+ +Y+
Sbjct: 1556 PDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYK 1615

Query: 1348 RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQ 1407
            +G  +S+ ++H P+DMV +  AK +Q +A++ +YR  YH +T LP+ L +  ++ A  +Q
Sbjct: 1616 KGYEASKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQ 1675

Query: 1408 SELRYKSDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLV 1466
            S+  YKSD    MKGIGW+ + S ++E AKKAGE++SE KYR+ P+ +KFT  +D+ +  
Sbjct: 1676 SDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQA 1735

Query: 1467 HAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTR 1523
              K++ ++ ++R+Y    + D  ++H   ++PD PD   +R+N + +SDK+Y+  WE+ +
Sbjct: 1736 LNKSNKLNMDKRLYTEKWNKDKTTIH---VMPDTPDILLSRVNQITMSDKLYKAGWEEEK 1792

Query: 1524 AGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRL 1583
               YD R DAI  + ARASR+IASD++YK+A+ + +G  IG+RS++DDP++ HF+ V ++
Sbjct: 1793 KKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKM 1852

Query: 1584 QSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHA 1643
            QSD EYKK + KS++ FH+  D   ++ AK+SQ++A++ +YR  +      P+ +    A
Sbjct: 1853 QSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELA 1912

Query: 1644 QKAHQLQSDVKYKSD-LNLTRGVGWTPPGSYKVEMARRAAELANAR 1688
            +   Q+QSD +YK+D  +  +G+GW P GS + E  ++A E+ + +
Sbjct: 1913 KNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEK 1958



 Score = 1135 bits (2936), Expect = 0.0
 Identities = 619/1646 (37%), Positives = 983/1646 (59%), Gaps = 57/1646 (3%)

Query: 60   KNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLAN 119
            K   + S   TP    ++   + +S +  + DG+  K++ H D K+KD E A       +
Sbjct: 109  KGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVS 168

Query: 120  ERAY---WTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMIT 175
            +  Y   W    +     P A   PE+V+ V+      ++ YTED+E  +    +P   +
Sbjct: 169  KVLYKQNWEDTKDKYLLPPDA---PELVQAVKNTAMFSKKLYTEDWEADKSL-FYPYNDS 224

Query: 176  PAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQ 235
            P  +R  +A +  S V YK+G  E+ ++F+ + D P++  +K      S  +Y EDYE +
Sbjct: 225  PELRRVAQAQKALSDVAYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENK 284

Query: 236  -RGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294
             +GK S     TP +++                        A   + A+ I TR+     
Sbjct: 285  IKGKWS----ETPCFEV------------------------ANARMNADNISTRK----- 311

Query: 295  GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQD 354
               Y E++E  + +  F    TP Y+  KKA   AS +KY++D+ K KG A Y+ LPA +
Sbjct: 312  ---YQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASE 368

Query: 355  NLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQN 414
            N  L+Q ++    +S+  YK++ E ++  SINYCETP+F+  + +  F+SD KYK++Y  
Sbjct: 369  NPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDKKYKDSYLK 428

Query: 415  HMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPL 474
             + G Y G   D    H MKV +  S+  YKA+Y+ D     +P T+T  Y+   KL   
Sbjct: 429  DILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYEAIKKLDQC 488

Query: 475  KDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVK 534
            KD  Y+   DK K++ VTD+P ++QA++N++QLS +NY+A +E  K    +P D P  ++
Sbjct: 489  KDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIPPDTPAFIQ 548

Query: 535  AKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKA 594
             K NA   S+  YK+ WEK+K K F++K+DA+ LLAAKA+ +  S++ YK++YEK KGK 
Sbjct: 549  HKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDYEKNKGKM 608

Query: 595  MGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR----FHLPMDMVNIRHAKKAQTL 646
            +G      D ++LHSL++AK  S+  YK+ +E++K +       P   ++ +    ++  
Sbjct: 609  IGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQLKNFSEAR 668

Query: 647  ASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQA 706
              DL  +  L  Y    ED       K     S+  YKA+    KG  +  +      +A
Sbjct: 669  YKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEA 728

Query: 707  KKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISK 766
             K      +  Y+   D+ KFT+VTDS  +  A+ + +  S + YKA +E    +  I  
Sbjct: 729  IKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPA 788

Query: 767  DEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 826
            D P F+Q R NA NLS+ +YK  WE  KAK F++++D++  LAAKA     S+V YK+DY
Sbjct: 789  DAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKDY 848

Query: 827  ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 886
            E+S+GK+IGA  +  D +M HSL+ +K QS+ EY+K +E +K+     LDM+ +  A+K+
Sbjct: 849  EKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDMLQVTQAKKS 908

Query: 887  QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLN 945
            Q +A+DV YK   H ++  P  + V+ AKKAY LQSD +Y+AD   WMKG GWV  GSL 
Sbjct: 909  QAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCGWVPFGSLE 968

Query: 946  VEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHY 1005
            +E+AK+A ++++EKKYRQHPD LKFTSI+D P  VQ++I+  Q  D  Y+ +GE I H Y
Sbjct: 969  MEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKY 1028

Query: 1006 TPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKY 1065
                DLP+ + AK+NA NISE  YK     L   GY LR DA+P +AAKA+ +  SD +Y
Sbjct: 1029 NLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQY 1088

Query: 1066 KEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVH 1125
            K+ +EK KG+M+G +SL+DD  L H +    +QSD  YKK +E +K++++ P DM  +V 
Sbjct: 1089 KKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA 1148

Query: 1126 AKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIP 1184
            AKKAQ + SN +YKH L  YT L + + L  +K   ++QS+N+Y+ D  N+M+G+  +  
Sbjct: 1149 AKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPI 1208

Query: 1185 GTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDA 1244
            G+L++E  KKA + ++E KYRQHP + K+T++ D+P ++ AK + +  ++ LYKA GED 
Sbjct: 1209 GSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDV 1268

Query: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304
            +H+YTM+  LP+F++AK NA N+SD  YK  W +L A+G  +  +A+P  AA+AS +IAS
Sbjct: 1269 KHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIAS 1328

Query: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMV 1364
            D+ Y+  + K +GK +G +S++DDP++ H   + +LQS+ +Y++   +++  +H P DMV
Sbjct: 1329 DYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMV 1388

Query: 1365 HLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIG 1423
             +  AK AQ +A++ +Y+   H +T LP+ + +   +  + +QS+  YK +    +KGIG
Sbjct: 1389 SITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIG 1448

Query: 1424 WLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSG 1483
            W+ + S ++E  KKAG+ ++E KYR+ PD++KFT+V DS  +V A+++    ++  Y+  
Sbjct: 1449 WIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVE 1508

Query: 1484 DAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASR 1543
              +  H+YT+ P+ P F +A++NAL++SD  Y+  W++T A  YD R DAIP   A++SR
Sbjct: 1509 GEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSR 1568

Query: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603
             IASD +YKEA+ + +G Q+G+ S+ DDP++ H++NV ++QSD EYKK +  S++++H+ 
Sbjct: 1569 NIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTP 1628

Query: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDL-NLT 1662
             D   +  AK+SQ++A++ +YRQ     T  P+ L + H++ A Q+QSD  YKSD  N  
Sbjct: 1629 LDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWM 1688

Query: 1663 RGVGWTPPGSYKVEMARRAAELANAR 1688
            +G+GW P  S +VE A++A E+ + +
Sbjct: 1689 KGIGWVPIESLEVEKAKKAGEILSEK 1714



 Score = 1052 bits (2721), Expect = 0.0
 Identities = 592/1572 (37%), Positives = 930/1572 (59%), Gaps = 75/1572 (4%)

Query: 136  GALPDPEIVRMVE-ARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYK 194
            G++ DP     ++ A ++  + Y  +YE+ +GK  FP  IT  Y+  KK +Q      YK
Sbjct: 683  GSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQTITQEYEAIKKLDQCKDHT-YK 741

Query: 195  RGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKR 254
               D+  ++F+ V D+P LL+++   +  SD+ Y   +E ++ K   PA      Q    
Sbjct: 742  VHPDK--TKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGEKFKCHIPADAPQFIQHRVN 799

Query: 255  ANELASDVRYHQQYQK------EMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGK 308
            A  L+ +V Y Q ++K      +++  A P + A+   T+  +D     Y ++YE+ +GK
Sbjct: 800  AYNLSDNV-YKQDWEKSKAKKFDIKVDAIPLLAAKA-NTKNTSDVM---YKKDYEKSKGK 854

Query: 309  --GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNK 366
              G+      P   ++ K  +  SD +YR+D+ K K     ++ P  D L + QA+    
Sbjct: 855  MIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSK---TIYTAPL-DMLQVTQAKKSQA 910

Query: 367  LVSEVEYKKDLESSRGHSINYCETPQFRNVSKISK---FTSDNKYKENYQNHMRGRYEGV 423
            + S+V+YK  L S       Y   P   NV    K     SD +YK +Y + M+G     
Sbjct: 911  IASDVDYKHILHS-------YSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKG----- 958

Query: 424  GMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSI 483
                     +  GSL    A +A    DI                     L +  YRQ  
Sbjct: 959  ------CGWVPFGSLEMEKAKRAS---DI---------------------LNEKKYRQHP 988

Query: 484  DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFS 543
            D LK++S+ D P  VQ+KIN  Q S + Y+A  E+    Y LP D+PQ ++AK NA   S
Sbjct: 989  DTLKFTSIEDAPITVQSKINQAQRSDIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNIS 1048

Query: 544  EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG----TAD 599
            E  YK   +    KG++++ DA+ + AAKA+ + AS+++YK++YEK KGK +G      D
Sbjct: 1049 ENMYKADLKDLSKKGYDLRTDAIPIRAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDD 1108

Query: 600  SRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEY 659
             +L+H + +AK+ S+ EYKK +E++K++++ P DM N+  AKKAQ + S+++Y+  LH Y
Sbjct: 1109 PKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHY 1168

Query: 660  TVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGWLTEGSLNLEQAKKAGQLVSEKNY 718
            T LP+ M  + +K    +QS+  YK D   WMKG+GW+  GSL++E+ KKAG  ++EK Y
Sbjct: 1169 TYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKY 1228

Query: 719  RQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANA 778
            RQ  D LKFTS+ DS  M  AK++ +  S + YKA  E   H+YT+S D P FLQA+ NA
Sbjct: 1229 RQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNA 1288

Query: 779  ANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKD 838
             N+S+  YK  W +  AKG  +  D++   AAKA R++AS+ KYKE YE+S+GK +G + 
Sbjct: 1289 YNISDVCYKRDWHDLIAKGNNVLGDAIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRS 1348

Query: 839  VQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTA 898
            +Q D ++ H + ++KLQS+ EYKK +E+TK+  H   DMV +  A+ AQ +AT+V YK  
Sbjct: 1349 LQDDPKLVHYMNVAKLQSDREYKKNYENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQP 1408

Query: 899  EHHFTALPTDMKVEWAKKAYGLQSDNQYRADV-KWMKGMGWVATGSLNVEQAKKAGELIS 957
             HH+T LP  M +E  +    +QSDN Y+ +   ++KG+GW+  GSL VE+ KKAG+ ++
Sbjct: 1409 LHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALN 1468

Query: 958  EKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLA 1017
            E+KYRQHPD +KFTS+ D+  MV A+ +  Q  D  Y+ +GE +KH YT   +LP+ + A
Sbjct: 1469 ERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLKHKYTIDPELPQFIQA 1528

Query: 1018 KLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQML 1077
            K+NA+N+S+  YK  W K    GY LR DA+P  AAK+S  I SD KYKEA+EK KG+ +
Sbjct: 1529 KVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAAKSSRNIASDCKYKEAYEKAKGKQV 1588

Query: 1078 GSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQD 1137
            G  SL+DD  L H +    +QSD  YKKG+E SK ++H PLDM ++  AKK+Q +A+N +
Sbjct: 1589 GFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLDMVSVTAAKKSQEVATNAN 1648

Query: 1138 YKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDL-NFMRGVACVIPGTLEIEGRKKAS 1196
            Y+     YT L + L +  ++ A ++QS+NLY+SD  N+M+G+  V   +LE+E  KKA 
Sbjct: 1649 YRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFTNWMKGIGWVPIESLEVEKAKKAG 1708

Query: 1197 ELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPE 1256
            E++SE KYRQHP   K+T   DT      K +    ++RLY       +    +    P+
Sbjct: 1709 EILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRLYTEKWNKDKTTIHVMPDTPD 1768

Query: 1257 FIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKER 1316
             + ++ N   +SD  YK  W   + +GY L  +A+  +AARAS DIASD+ Y+  + + +
Sbjct: 1769 ILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAARASRDIASDYKYKKAYEQAK 1828

Query: 1317 GKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALA 1376
            GK IG +S+ DDP++ H  ++ ++QS+ +Y++G   S+  FH P+DM+ +V AK +Q +A
Sbjct: 1829 GKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTSFHTPVDMLSVVAAKKSQEVA 1888

Query: 1377 SDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIG-MKGIGWLALRSPQMESA 1435
            ++ +YR   H +  LP+ +    AK    +QS+ +YK+D    MKGIGWL L S + E  
Sbjct: 1889 TNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADYADFMKGIGWLPLGSLEAEKN 1948

Query: 1436 KKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIP 1495
            KKA E+ISE KYR+ PD++K++T++DS ++V A+N+    NE +Y+        +  ++P
Sbjct: 1949 KKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIMNEHLYKQAWEADKTKVHIMP 2008

Query: 1496 DHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAF 1555
            D P    A+ NA+++SDK+Y+ S E+++   YD R DAIP + A+ASR+IASD++YK  +
Sbjct: 2009 DIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIPIKAAKASRDIASDYKYKYNY 2068

Query: 1556 LRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRS 1615
             + +G  +G+RS++DDP++ H + V ++QSD EYKK++  +++ +H+  D   +  AK +
Sbjct: 2069 EKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENTKTSYHTPADMLSVTAAKDA 2128

Query: 1616 QQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLN-LTRGVGWTPPGSYK 1674
            Q   ++ +Y+  + +    P+ + +   +  +++QSD +YK D N   +G+GW+P GS +
Sbjct: 2129 QANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEYKQDYNEWYKGLGWSPAGSLE 2188

Query: 1675 VEMARRAAELAN 1686
            VE A++A E A+
Sbjct: 2189 VEKAKKATEYAS 2200



 Score = 1038 bits (2683), Expect = 0.0
 Identities = 592/1602 (36%), Positives = 935/1602 (58%), Gaps = 82/1602 (5%)

Query: 140  DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198
            DP++V  +   K   + EY +DYE+ + K + P  +      AKKA  + S V YK    
Sbjct: 1108 DPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTPHDMFNVVA-AKKAQDVVSNVNYKHS-- 1164

Query: 199  ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ-QRGKGSFPAMITPAYQIAKRANE 257
              +  ++ + D  +L  SK   Q+QSD  Y EDY    +G G  P       ++ K  + 
Sbjct: 1165 --LHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWMKGIGWIPIGSLDVEKVKKAGDA 1222

Query: 258  L-ASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMIT 316
            L     R H    K    +  P +      T++ +D     Y  + E+ + K +    + 
Sbjct: 1223 LNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL---YKAKGEDVKHKYTMSPDL- 1278

Query: 317  PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA------QSVNKLVSE 370
            P +  AK      SD+ Y++D         +H L A+ N VL  A      ++   + S+
Sbjct: 1279 PQFLQAKCNAYNISDVCYKRD---------WHDLIAKGNNVLGDAIPITAAKASRNIASD 1329

Query: 371  VEYKKDLESSRGHSINYC---ETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427
             +YK+  E S+G  + +    + P+  +   ++K  SD +YK+NY+N  +  Y   G D 
Sbjct: 1330 YKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYEN-TKTSYHTPG-DM 1387

Query: 428  RTLHAMKVGSLASNVAYKADYKHDIVDYNY-PATLT-----------------PSYQTAM 469
             ++ A K   +A +VA   +YK  +  Y Y P  ++                   Y + +
Sbjct: 1388 VSITAAK---MAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEYNSFL 1444

Query: 470  KLV------------------PLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 511
            K +                   L +  YRQ  D +K++SV D+  +V A+ N +QLS +N
Sbjct: 1445 KGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLN 1504

Query: 512  YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571
            Y+ + EK K  YT+  ++PQ ++AK NA   S+  YK  W+KT  KG++++ DA+ ++AA
Sbjct: 1505 YKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIPIVAA 1564

Query: 572  KASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTR 627
            K+S  +AS+ KYKE YEK KGK +G      D +L+H + +AK+ S+ EYKKG+E SKT+
Sbjct: 1565 KSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTK 1624

Query: 628  FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 687
            +H P+DMV++  AKK+Q +A++ +YR+  H YT+LP+ +  + ++ A  +QS+  YK+D 
Sbjct: 1625 YHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDF 1684

Query: 688  A-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQ 746
              WMKG+GW+   SL +E+AKKAG+++SEK YRQ  ++LKFT   D+ +    K ++   
Sbjct: 1685 TNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNM 1744

Query: 747  SGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLT 806
                Y     +      +  D P  L +R N   +S+KLYK+ WE +K KG++LR D++ 
Sbjct: 1745 DKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIA 1804

Query: 807  FLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED 866
              AA+A RD+AS+ KYK+ YE+++GK IG + ++ D ++ H +Q++K+QS+ EYKKG+E 
Sbjct: 1805 IKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEK 1864

Query: 867  TKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQY 926
            +K+  H  +DM+ +V A+K+Q +AT+  Y+   H +  LP  M  E AK    +QSDNQY
Sbjct: 1865 SKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQY 1924

Query: 927  RAD-VKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARIS 985
            +AD   +MKG+GW+  GSL  E+ KKA E+ISEKKYRQHPD LK++++ D+  MV A+ +
Sbjct: 1925 KADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNN 1984

Query: 986  YTQAVDRLYRE--QGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKL 1043
                 + LY++  + +  K H  P  D+P+++LAK NA+N+S+  YK S  + +  GY L
Sbjct: 1985 AKIMNEHLYKQAWEADKTKVHIMP--DIPQIILAKANAINMSDKLYKLSLEESKKKGYDL 2042

Query: 1044 RLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNY 1103
            R DA+P +AAKAS +I SDYKYK  +EK KG+M+G RSLEDD  L HS+    +QSD  Y
Sbjct: 2043 RPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREY 2102

Query: 1104 KKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKL 1163
            KK +E++K  +H P DM ++  AK AQ   +N +YKH + +Y  L + + +   +  +++
Sbjct: 2103 KKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRI 2162

Query: 1164 QSENLYRSDLN-FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNL 1222
            QS+N Y+ D N + +G+     G+LE+E  KKA+E  S+ KYRQHP +F++  +TD+ ++
Sbjct: 2163 QSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDM 2222

Query: 1223 LHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQ 1282
            + AK +    N+ LY       + +  +    P+ ++AK N    S   YK  W     +
Sbjct: 2223 VLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKK 2282

Query: 1283 GYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQS 1342
            GY L ++A+  Q A+AS DIASD+ Y+  + K+ G  +G +S++DDP++     + ++QS
Sbjct: 2283 GYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQS 2342

Query: 1343 ELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKK 1402
            E +Y++     + +F  P+DM+ +V AK  Q L SD DY+   H++T LP+   +  AKK
Sbjct: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKK 2402

Query: 1403 AHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDS 1462
             + LQSE  YKSDL  ++GIGW  L S + E  K+A E+ISE KYR+ PD  KFT++ D+
Sbjct: 2403 VYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDA 2462

Query: 1463 PDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQT 1522
             D+V AK +  + ++R+YR    +   +  ++PD PD   A+ N ++ SDK+YR  +E+ 
Sbjct: 2463 MDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEEL 2522

Query: 1523 RAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGR 1582
            +   YD  +DAIP + A+ASREIAS+++YKE F +  G  IG R+++DDP+M   ++V +
Sbjct: 2523 KRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAK 2582

Query: 1583 LQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRH 1642
            +QSD EYKKDF K +++F S  D  G++ AK+ Q L SDV Y+  L Q TC P+Q  + H
Sbjct: 2583 IQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIH 2642

Query: 1643 AQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684
            A++A+ LQSD  YKSDL   +G+GW   GS + E  +RA ++
Sbjct: 2643 ARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQI 2684



 Score = 1022 bits (2642), Expect = 0.0
 Identities = 603/1626 (37%), Positives = 937/1626 (57%), Gaps = 61/1626 (3%)

Query: 109  EGAPNRQPLANERAYWTGYGEGNAWCPGALP---DPEIVRMVEARKSLGE-EYTEDYEQP 164
            + A   + +A++  Y   Y +G     G      DP++V  ++  K   + EY ++YE  
Sbjct: 2050 KAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYENT 2109

Query: 165  RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224
            +     PA +  +   AK A    +   YK      I ++  + D   +  ++   ++QS
Sbjct: 2110 KTSYHTPADML-SVTAAKDAQANITNTNYKH----LIHKYILLPDAMNIELTRNMNRIQS 2164

Query: 225  DVRYTEDY-EQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQ----KEMRGMAGPA 279
            D  Y +DY E  +G G  PA      + AK+A E ASD +Y Q       K++       
Sbjct: 2165 DNEYKQDYNEWYKGLGWSPAGSLEVEK-AKKATEYASDQKYRQHPSNFQFKKLTDSMDMV 2223

Query: 280  IGAEGILT-----------------------------RECADQYGQG-YPEEYEEHRGKG 309
            +  +   T                             ++    Y Q  Y   +EE   KG
Sbjct: 2224 LAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKG 2283

Query: 310  SFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVS 369
                +   + Q AK + ++ASD KY+Q + K  G  H      QD+  L  + +V K+ S
Sbjct: 2284 YDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGH-HVGFRSLQDDPKLVLSMNVAKMQS 2342

Query: 370  EVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRT 429
            E EYKKD E  +    +  +        K  +  SD  YK NY +    ++  +      
Sbjct: 2343 EREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYK-NYLH----QWTCLPDQNDV 2397

Query: 430  LHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489
            + A KV  L S   YK+D +        P     + +       + +  YRQ  D+ K++
Sbjct: 2398 VQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFT 2457

Query: 490  SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549
            S+ D   IV AK NA+  S   YR  ++K+K    +  D P +V AK N    S+  Y+ 
Sbjct: 2458 SIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRM 2517

Query: 550  GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605
            G+E+ K KG+++ +DA+ + AAKAS E+AS  KYKE + K  G  +G      D +++ S
Sbjct: 2518 GYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWS 2577

Query: 606  LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665
            + +AK+ S+ EYKK FE+ KT+F  P+DM+ +  AKK QTL SD+DY+  LH++T LP+ 
Sbjct: 2578 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ 2637

Query: 666  MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725
                 A++AY LQS+  YK+DL W+KG+GW+T GSL  E+ K+A Q++S+  YRQ  D+ 
Sbjct: 2638 SDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQF 2697

Query: 726  KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785
            KF+S+ DS  M  AK +    +   Y    ++      I  D P  L A+ N  N SEKL
Sbjct: 2698 KFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKL 2757

Query: 786  YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845
            YK   E  K KG+++R+D++   AAKA RD+ASE KYKE Y +  G  IGA+ ++ D +M
Sbjct: 2758 YKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKM 2817

Query: 846  SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905
              S+ ++K+QS+ EYKK FE  K++    +DM+ +V A+K Q L +DV YK   H +T L
Sbjct: 2818 MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCL 2877

Query: 906  PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965
            P    V  A++AY LQSDN Y++D++WM+G+GWV+ GSL+VE+ K+A E++S+K YRQ P
Sbjct: 2878 PDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPP 2937

Query: 966  DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025
            D  KFTS+ D+ E V A+ +      RLY E  +  K       D PE++LA+ N +N S
Sbjct: 2938 DRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYS 2997

Query: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085
            ET YK +  + +  GY LR DA+P  AAKAS ++ISDYKYK+ + K  G  +G+R++EDD
Sbjct: 2998 ETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD 3057

Query: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145
              +  S++   +QSD  YKK FE  K +F  P+DM  +V AKK QTL S+ DYK+ L ++
Sbjct: 3058 PKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEW 3117

Query: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205
            T L +   +  A++A+ LQS+N+Y+SDL ++RG+  V  G++++   K+A+E++S++ YR
Sbjct: 3118 TCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYR 3177

Query: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265
            Q P   K+T+VTD+   + AK +    N+RLY  A +  + +  +    PE + A+ N  
Sbjct: 3178 QPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKI 3237

Query: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325
            N S++ Y+++    + +GY L  +A+P  AA+AS DIASD+ Y+  + K+ G  IG ++V
Sbjct: 3238 NYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAV 3297

Query: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385
             DDP+I     + ++QS+ +Y++     + ++  P+DM+ +V AK  Q L SD DY+   
Sbjct: 3298 HDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPL 3357

Query: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445
            H++  LP+   +  A+KA+ LQS+  YKSDL  MKGIGW+ + S ++  AK+AGEL+S+T
Sbjct: 3358 HEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDT 3417

Query: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502
             YR++P+++KFT++ D+P+ V AKN+ ++ N+R+Y      D +++H   ++PD P+   
Sbjct: 3418 IYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIH---VMPDTPEIML 3474

Query: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562
            A+LN ++ SDK+Y+ + E+++   YD RLDAIP Q A+ASR+IASD++YKE + +  G  
Sbjct: 3475 AKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHH 3534

Query: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622
            IG R++ DDP+M   ++V ++QSD EYKK+F K +++F S  D  G++ AK+ Q L SD+
Sbjct: 3535 IGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDI 3594

Query: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682
             Y+ PL + TC P+Q  +  A+KA+ LQSD  YKSDL   RG+GW P GS +VE  +RA 
Sbjct: 3595 DYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAG 3654

Query: 1683 ELANAR 1688
            E+ + R
Sbjct: 3655 EILSDR 3660



 Score = 1021 bits (2639), Expect = 0.0
 Identities = 589/1588 (37%), Positives = 926/1588 (58%), Gaps = 59/1588 (3%)

Query: 140  DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198
            DP++V  +   K   E EY +D+E+ + K S P  +      AKK  +L S V+YK    
Sbjct: 2328 DPKLVLSMNVAKMQSEREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQELVSDVDYKN--- 2383

Query: 199  ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258
              + +++ + D  +++++K   +LQS+  Y  D E  RG G  P     A +  KRA+E+
Sbjct: 2384 -YLHQWTCLPDQNDVVQAKKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEK-NKRASEI 2441

Query: 259  ASDVRYHQQYQKEMRGMAGPAI----------GAEGILTRECADQ--------------- 293
             S+ +Y Q   +        A+               L RE  D+               
Sbjct: 2442 ISEKKYRQPPDRNKFTSIPDAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIV 2501

Query: 294  ---------YGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344
                       + Y   YEE + KG    +     + AK + E+AS+ KY++ F K  G 
Sbjct: 2502 LAKANLINTSDKLYRMGYEELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGH 2561

Query: 345  AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404
             H  +   +D+  +  +  V K+ S+ EYKKD E  +    +  +        K     S
Sbjct: 2562 -HIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVS 2620

Query: 405  DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH-DIVDYNYPATLTP 463
            D  YK NY +    ++  +      +HA +   L S+  YK+D +    + +    +L  
Sbjct: 2621 DVDYK-NYLH----QWTCLPDQSDVIHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLED 2675

Query: 464  SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNY 523
                    + L D  YRQ  D+ K+SS+ D+  +V AK NA  ++H  Y   ++K+K   
Sbjct: 2676 EKNKRATQI-LSDHVYRQHPDQFKFSSLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTV 2734

Query: 524  TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKY 583
             +  D P+++ AK N   +SE  YK G E+ K KG++M++DA+ + AAKAS ++AS  KY
Sbjct: 2735 HIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKY 2794

Query: 584  KEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRH 639
            KE Y K  G  +G      D +++ S+ +AK+ S+ EYKK FE+ KT+F  P+DM+ +  
Sbjct: 2795 KEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL 2854

Query: 640  AKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEG 699
            AKK QTL SD+DY+  LH++T LP+      A++AY LQS+  YK+DL WM+G+GW++ G
Sbjct: 2855 AKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIG 2914

Query: 700  SLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 759
            SL++E+ K+A +++S+K YRQ  D  KFTSVTDS +   AK +    +   Y    ++  
Sbjct: 2915 SLDVEKCKRATEILSDKIYRQPPDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDK 2974

Query: 760  HQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASE 819
             Q  I  D P  + AR N  N SE LYK + E  K KG++LR D++  +AAKA RD+ S+
Sbjct: 2975 TQIHIMPDTPEIMLARQNKINYSETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISD 3034

Query: 820  VKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVH 879
             KYK+ Y +  G  IGA++++ D +M  S+ ++K+QS+ EYKK FE  K++    +DM+ 
Sbjct: 3035 YKYKDGYRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLG 3094

Query: 880  LVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWV 939
            +V A+K Q L +DV YK   H +T LP    V  A++AY LQSDN Y++D++W++G+GWV
Sbjct: 3095 VVLAKKCQTLVSDVDYKNYLHEWTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWV 3154

Query: 940  ATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGE 999
              GS++V + K+A E++S+  YRQ PD LKFTS+ D+ E V A+ +      RLY E  +
Sbjct: 3155 PIGSMDVVKCKRAAEILSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWD 3214

Query: 1000 NIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEI 1059
              K       D PE++LA+ N +N SE+ Y+++  + +  GY LR DA+P  AAKAS +I
Sbjct: 3215 KDKTQVHIMPDTPEIMLARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDI 3274

Query: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119
             SDYKYKEA+ K  G  +G+R++ DD  +  S++   +QSD  YKK FE  K ++  P+D
Sbjct: 3275 ASDYKYKEAYRKQLGHHIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVD 3334

Query: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179
            M  +V AKK QTL S+ DYKHPL ++  L +   +  A+KA+ LQS+NLY+SDL +M+G+
Sbjct: 3335 MLGIVLAKKCQTLVSDVDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGI 3394

Query: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKA 1239
              V   +LE+   K+A EL+S++ YRQ P + K+T++TDTP  + AK +    N+RLY  
Sbjct: 3395 GWVPIDSLEVVRAKRAGELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTE 3454

Query: 1240 AGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARAS 1299
            A ++ +    +    PE + AK N  N SD  YK +    + +GY L ++A+P QAA+AS
Sbjct: 3455 AWDNDKKTIHVMPDTPEIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKAS 3514

Query: 1300 GDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHL 1359
             DIASD+ Y+  + K+ G  IG ++++DDP++     + ++QS+ +Y++     + +F  
Sbjct: 3515 RDIASDYKYKEGYRKQLGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSS 3574

Query: 1360 PMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGM 1419
            P+DM+ +V AK  Q L SD DY+   H++T LP+   +  A+KA+ LQS+  YKSDL  +
Sbjct: 3575 PVDMLGVVLAKKCQILVSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWL 3634

Query: 1420 KGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERM 1479
            +GIGW+ + S ++E  K+AGE++S+ KYR+  D +KFT + D+P++V AKN+ +  ++ +
Sbjct: 3635 RGIGWVPIGSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHL 3694

Query: 1480 YR---SGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPF 1536
            Y      D  S+H   ++PD PD   A+ N+ ++S K+Y   W++++   YD R DAI  
Sbjct: 3695 YTEAWDADKTSIH---VMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISI 3751

Query: 1537 QTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKS 1596
            ++A+ASR+IASD++YKEA+ + +G  IG +S++DDP++   ++ G++QS+ EYKK+F K 
Sbjct: 3752 KSAKASRDIASDYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKW 3811

Query: 1597 RSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYK 1656
            +++F S  D   +L AK+ Q L +D+ YR  L + TC P+Q  +  A+KA+ LQSD  YK
Sbjct: 3812 KTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYK 3871

Query: 1657 SDLNLTRGVGWTPPGSYKVEMARRAAEL 1684
            +DL   RG+GW P GS +V   + A  +
Sbjct: 3872 ADLEWLRGIGWMPQGSPEVLRVKNAQNI 3899



 Score =  979 bits (2531), Expect = 0.0
 Identities = 582/1622 (35%), Positives = 924/1622 (56%), Gaps = 63/1622 (3%)

Query: 109  EGAPNRQPLANERAYWTGYGEGNAWCPGAL---PDPEIVRMVEARKSLGE-EYTEDYEQP 164
            + A   + +A+E  Y  G+ +      GA     DP+++  +   K   + EY +D+E+ 
Sbjct: 2537 KAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDREYKKDFEKW 2596

Query: 165  RGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQS 224
            + K S P  +      AKK   L S V+YK      + +++ + D  +++ ++    LQS
Sbjct: 2597 KTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCLPDQSDVIHARQAYDLQS 2651

Query: 225  DVRYTEDYEQQRGKG-------------------------------SFPAMITPAYQIAK 253
            D  Y  D +  +G G                                F +++     +  
Sbjct: 2652 DNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPMVLA 2711

Query: 254  RANELASDVR-YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSF 311
            + N +  + R Y + + K+   +       E +L ++    Y +  Y    EE + KG  
Sbjct: 2712 KNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRKGYD 2771

Query: 312  PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371
              +     + AK + ++AS+ KY++ + K  G  H  +   +D+  +  +  V K+ S+ 
Sbjct: 2772 MRVDAIPIKAAKASRDIASEFKYKEGYRKQLGH-HIGARAIRDDPKMMWSMHVAKIQSDR 2830

Query: 372  EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431
            EYKKD E  +    +  +        K     SD  YK NY +    ++  +      +H
Sbjct: 2831 EYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYK-NYLH----QWTCLPDQSDVIH 2885

Query: 432  AMKVGSLASNVAYKAD--YKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYS 489
            A +   L S+  YK+D  +   I   +  +      + A ++  L D  YRQ  D+ K++
Sbjct: 2886 ARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEI--LSDKIYRQPPDRFKFT 2943

Query: 490  SVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKE 549
            SVTD+ + V AK NA  ++   Y   ++K+K    +  D P+++ A+ N   +SE  YK 
Sbjct: 2944 SVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYSETLYKL 3003

Query: 550  GWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA----DSRLLHS 605
              E+ K KG++++ DA+ ++AAKAS ++ S+ KYK+ Y K  G  +G      D +++ S
Sbjct: 3004 ANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDDPKMMWS 3063

Query: 606  LQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPED 665
            + +AK+ S+ EYKK FE+ KT+F  P+DM+ +  AKK QTL SD+DY+  LHE+T LP+ 
Sbjct: 3064 MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCLPDQ 3123

Query: 666  MKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725
                 A++AY LQS+  YK+DL W++G+GW+  GS+++ + K+A +++S+  YRQ  D+L
Sbjct: 3124 NDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYRQPPDKL 3183

Query: 726  KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785
            KFTSVTDS +   AK +    +   Y    ++   Q  I  D P  + AR N  N SE L
Sbjct: 3184 KFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKINYSESL 3243

Query: 786  YKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQM 845
            Y+ + E  K +G++LR D++  +AAKA RD+AS+ KYKE Y +  G  IGA+ V  D ++
Sbjct: 3244 YRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAVHDDPKI 3303

Query: 846  SHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905
              SL ++K+QS+ EYKK FE  K++    +DM+ +V A+K Q L +DV YK   H +  L
Sbjct: 3304 MWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPLHEWICL 3363

Query: 906  PTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHP 965
            P    +  A+KAY LQSDN Y++D++WMKG+GWV   SL V +AK+AGEL+S+  YRQ P
Sbjct: 3364 PDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDTIYRQRP 3423

Query: 966  DALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNIS 1025
            + LKFTSI DTPE V A+ +      RLY E  +N K       D PE++LAKLN +N S
Sbjct: 3424 ETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKLNRINYS 3483

Query: 1026 ETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDD 1085
            +  YK +  + +  GY LRLDA+P QAAKAS +I SDYKYKE + K  G  +G+R+++DD
Sbjct: 3484 DKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGARNIKDD 3543

Query: 1086 ISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQY 1145
              +  S++   +QSD  YKK FE  K +F  P+DM  +V AKK Q L S+ DYKHPL ++
Sbjct: 3544 PKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYKHPLHEW 3603

Query: 1146 TSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYR 1205
            T L +   +  A+KA+ LQS+ +Y+SDL ++RG+  V  G++E+E  K+A E++S+ KYR
Sbjct: 3604 TCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEILSDRKYR 3663

Query: 1206 QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAA 1265
            Q     K+T +TDTP ++ AK +    ++ LY  A +  +    +    P+ + AK+N+A
Sbjct: 3664 QPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILLAKSNSA 3723

Query: 1266 NLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSV 1325
            N+S   Y + W   + + Y L  +A+  ++A+AS DIASD+ Y+  + K++G  IG QS+
Sbjct: 3724 NISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSI 3783

Query: 1326 RDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQY 1385
             DDP+I      G++QSE +Y++     + +F  P+DM+ ++ AK  Q L +D DYR   
Sbjct: 3784 EDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYL 3843

Query: 1386 HKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISET 1445
            H++T +P+   +  AKKA+ LQS+  YK+DL  ++GIGW+   SP++   K A  +  ++
Sbjct: 3844 HEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDS 3903

Query: 1446 KYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYR---SGDAESLHRYTLIPDHPDFTR 1502
             YR    ++K+T++VD+P++V AK++  + +   YR     D  S+H   ++PD P+   
Sbjct: 3904 VYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIH---IMPDTPEINL 3960

Query: 1503 ARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562
            AR NAL++S+K+YR  W++ +AG  D RLDAIP Q A+ASREIASD++YK    + +G  
Sbjct: 3961 ARANALNVSNKLYREGWDEMKAGC-DVRLDAIPIQAAKASREIASDYKYKLDHEKQKGHY 4019

Query: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622
            +G  +  DD +++  L   +LQ++ EY+ D+AK +++  S  D   +L +K SQ L SD+
Sbjct: 4020 VGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDM 4079

Query: 1623 HYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAA 1682
             YR  L Q TC P+Q  +  A+KA++LQSD  YK+DL   RG+GW P  S  V  A+ AA
Sbjct: 4080 DYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAA 4139

Query: 1683 EL 1684
            ++
Sbjct: 4140 DI 4141



 Score =  979 bits (2530), Expect = 0.0
 Identities = 592/1719 (34%), Positives = 941/1719 (54%), Gaps = 108/1719 (6%)

Query: 55   HAHNPKNNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHW--DMKS--KDKEG 110
            +  +P    FTS+  +P+ +  +   + +S I  +  GE  K  +    D+    + K  
Sbjct: 1228 YRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCN 1287

Query: 111  APNRQPLANERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEE--YTEDYEQPRGK- 167
            A N   +  +R +     +GN     A+P    +   +A +++  +  Y E YE+ +GK 
Sbjct: 1288 AYNISDVCYKRDWHDLIAKGNNVLGDAIP----ITAAKASRNIASDYKYKEAYEKSKGKH 1343

Query: 168  -GSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDV 226
             G       P         +L S  EYK+ ++       T   TP  + S   A++  DV
Sbjct: 1344 VGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENT----KTSYHTPGDMVSITAAKMAQDV 1399

Query: 227  RYTEDYEQQRGKGSF--PAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEG 284
                +Y+Q     ++   AM   + +  +  N++ SD  Y  +Y   ++G+    IG+  
Sbjct: 1400 ATNVNYKQPLHHYTYLPDAM---SLEHTRNVNQIQSDNVYKDEYNSFLKGIGWIPIGS-- 1454

Query: 285  ILTRECADQYGQGYPE-EYEEHRGKGSFPAM-----ITPAYQNAKKAHEL---------- 328
             L  E   + G    E +Y +H     F ++     +  A  N K+  +L          
Sbjct: 1455 -LEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQLSDLNYKVEGEKLK 1513

Query: 329  ---------------------ASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367
                                  SD  Y+ D+ K   A  Y   P  D + +  A+S   +
Sbjct: 1514 HKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTI-AKGYDLRP--DAIPIVAAKSSRNI 1570

Query: 368  VSEVEYKKDLESSRGHSINYC---ETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVG 424
             S+ +YK+  E ++G  + +    + P+  +   ++K  SD +YK+ Y+      +  + 
Sbjct: 1571 ASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEASKTKYHTPLD 1630

Query: 425  MDRRTLHAMKVGSLASNVAYKADYKHDIV------------------DYNYPATLTPSYQ 466
            M   T  A K   +A+N  Y+  Y H  +                  D  Y +  T ++ 
Sbjct: 1631 MVSVTA-AKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLYKSDFT-NWM 1688

Query: 467  TAMKLVP---------------LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVN 511
              +  VP               L +  YRQ  +KLK++   DT +    K N   +    
Sbjct: 1689 KGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSNKLNMDKRL 1748

Query: 512  YRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571
            Y   + K+K    +  D P ++ ++ N    S+  YK GWE+ K KG++++ DA+++ AA
Sbjct: 1749 YTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRPDAIAIKAA 1808

Query: 572  KASGELASNIKYKEEYEKTKGKAMG----TADSRLLHSLQIAKMSSEVEYKKGFEESKTR 627
            +AS ++AS+ KYK+ YE+ KGK +G      D +L+H +Q+AKM S+ EYKKG+E+SKT 
Sbjct: 1809 RASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKKGYEKSKTS 1868

Query: 628  FHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADL 687
            FH P+DM+++  AKK+Q +A++ +YR  +H Y +LP+ M  + AK    +QS+ QYKAD 
Sbjct: 1869 FHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQSDNQYKADY 1928

Query: 688  A-WMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQ 746
            A +MKG+GWL  GSL  E+ KKA +++SEK YRQ  D LK++++ DS  M  A+ + ++ 
Sbjct: 1929 ADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVLAQNNAKIM 1988

Query: 747  SGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLT 806
            +   YK   E    +  I  D P  + A+ANA N+S+KLYK S E  K KG++LR D++ 
Sbjct: 1989 NEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGYDLRPDAIP 2048

Query: 807  FLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED 866
              AAKA RD+AS+ KYK +YE+ +GK++G + ++ D ++ HS+Q++K+QS+ EYKK +E+
Sbjct: 2049 IKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDREYKKNYEN 2108

Query: 867  TKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQY 926
            TK+  H   DM+ +  A+ AQ   T+  YK   H +  LP  M +E  +    +QSDN+Y
Sbjct: 2109 TKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMNRIQSDNEY 2168

Query: 927  RADV-KWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARIS 985
            + D  +W KG+GW   GSL VE+AKKA E  S++KYRQHP   +F  + D+ +MV A+ +
Sbjct: 2169 KQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSMDMVLAKQN 2228

Query: 986  YTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRL 1045
                   LY       K       D P++L AK N    S+  YK  W +    GY L +
Sbjct: 2229 AHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEALKKGYDLPV 2288

Query: 1046 DALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKK 1105
            DA+  Q AKAS +I SDYKYK+ + K  G  +G RSL+DD  L  S+    +QS+  YKK
Sbjct: 2289 DAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKMQSEREYKK 2348

Query: 1106 GFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQS 1165
             FE  K +F  P+DM  +V AKK Q L S+ DYK+ L Q+T L +   +  AKK ++LQS
Sbjct: 2349 DFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQAKKVYELQS 2408

Query: 1166 ENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHA 1225
            ENLY+SDL ++RG+     G+LE E  K+ASE+ISE KYRQ P   K+T++ D  +++ A
Sbjct: 2409 ENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIPDAMDIVLA 2468

Query: 1226 KFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYK 1285
            K + +  ++RLY+ A +  + +  +    P+ + AK N  N SD  Y+  +  L+ +GY 
Sbjct: 2469 KTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYEELKRKGYD 2528

Query: 1286 LTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQ 1345
            L ++A+P +AA+AS +IAS++ Y+  F K+ G  IG +++ DDP++     + ++QS+ +
Sbjct: 2529 LPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHVAKIQSDRE 2588

Query: 1346 YRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHA 1405
            Y++     + +F  P+DM+ +V AK  Q L SD DY+   H++T LP+   +  A++A+ 
Sbjct: 2589 YKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQAYD 2648

Query: 1406 LQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDL 1465
            LQS+  YKSDL  +KGIGW+   S + E  K+A +++S+  YR+ PD  KF++++DS  +
Sbjct: 2649 LQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFSSLMDSIPM 2708

Query: 1466 VHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAG 1525
            V AKN+ +  N R+Y     +      ++PD P+   A+ N ++ S+K+Y+   E+ +  
Sbjct: 2709 VLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKRK 2768

Query: 1526 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1585
             YD R+DAIP + A+ASR+IAS+F+YKE + +  G  IG R++ DDP+M   ++V ++QS
Sbjct: 2769 GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMHVAKIQS 2828

Query: 1586 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1645
            D EYKKDF K +++F S  D  G++ AK+ Q L SDV Y+  L Q TC P+Q  + HA++
Sbjct: 2829 DREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDVIHARQ 2888

Query: 1646 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAEL 1684
            A+ LQSD  YKSDL   RG+GW   GS  VE  +RA E+
Sbjct: 2889 AYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEI 2927



 Score =  794 bits (2051), Expect = 0.0
 Identities = 480/1477 (32%), Positives = 792/1477 (53%), Gaps = 62/1477 (4%)

Query: 229  TEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTR 288
            T DYEQ   + S PA+  PA  +A+ A+    + R   + + +      P I      ++
Sbjct: 39   TSDYEQS--ETSKPALAQPA--LAQPASAKPVERRKVIRKKVDPSKFMTPYIAH----SQ 90

Query: 289  ECADQYGQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY 347
            +  D +    Y E++E+ +G+       TP  +  KK  +  S++KYR D +  K   H 
Sbjct: 91   KMQDLFSPNKYKEKFEKTKGQPYASTTDTPELRRIKKVQDQLSEVKYRMDGDVAKTICHV 150

Query: 348  HSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNK 407
                A+D   ++ A+ V++ VS+V YK++ E ++   +   + P+     K +   S   
Sbjct: 151  DE-KAKD---IEHAKKVSQQVSKVLYKQNWEDTKDKYLLPPDAPELVQAVKNTAMFSKKL 206

Query: 408  YKENYQ--NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSY 465
            Y E+++    +   Y      RR   A K     S+VAYK         +  P    P  
Sbjct: 207  YTEDWEADKSLFYPYNDSPELRRVAQAQKA---LSDVAYKKGLAEQQAQFT-PLADPPDI 262

Query: 466  QTAMKLV-PLKDANYRQSIDKLKYSSVTDTP--QIVQAKINAQQLSHVNYRADYEKNKLN 522
            + A K+   +    Y++  +       ++TP  ++  A++NA  +S   Y+ D+E  K  
Sbjct: 263  EFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANARMNADNISTRKYQEDFENMKDQ 322

Query: 523  -YTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAM---SLLAAKASGELA 578
             Y +  + P+    K      S+VKYKE +EK KGK     L A     L   KA+G+  
Sbjct: 323  IYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKADYNVLPASENPQLRQLKAAGDAL 382

Query: 579  SNIKYKEEYEKTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIR 638
            S+  YKE YEKTK K++   ++                          +F L   + N  
Sbjct: 383  SDKLYKENYEKTKAKSINYCET-------------------------PKFKLDTVLQNFS 417

Query: 639  HAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTE 698
              KK +    D   +  L  Y    ED       K     S+  YKA+    +G G+  +
Sbjct: 418  SDKKYK----DSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQ 473

Query: 699  GSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQS 758
                  +A K      +  Y+   D+ KFT VTDS  +  A+ + +  S + YKA +E  
Sbjct: 474  TITQEYEAIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESE 533

Query: 759  VHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLAS 818
              +  I  D P F+Q + NA NLS+ LYK  WE  KAK F++++D++  LAAKA     S
Sbjct: 534  KFKCHIPPDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS 593

Query: 819  EVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQ----CHVS 874
            +V YK+DYE+++GK+IG   +  D +M HSL+++K QS+  YK+ +E TK++    C   
Sbjct: 594  DVMYKKDYEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETP 653

Query: 875  LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMK 934
               +       ++    D+  K    H+     D       K     SD  Y+A+ +  K
Sbjct: 654  KYQLDTQLKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDK 713

Query: 935  GMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLY 994
            G  +         +A K  +   +  Y+ HPD  KFT++ D+P ++QA+++  Q  D  Y
Sbjct: 714  GKCYFPQTITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNY 773

Query: 995  REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1054
            + + E  K      AD P+ +  ++NA N+S+  YK+ W K +   + +++DA+P  AAK
Sbjct: 774  KAKHEGEKFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAK 833

Query: 1055 ASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQF 1114
            A+ +  SD  YK+ +EK KG+M+G+ S+ DD  + HS+     QSD  Y+K +E SK  +
Sbjct: 834  ANTKNTSDVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIY 893

Query: 1115 HLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN 1174
              PLDM  +  AKK+Q +AS+ DYKH L  Y+   + + +  AKKA+ LQS+  Y++D N
Sbjct: 894  TAPLDMLQVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYN 953

Query: 1175 -FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITN 1233
             +M+G   V  G+LE+E  K+AS++++E KYRQHP + K+T++ D P  + +K +    +
Sbjct: 954  SWMKGCGWVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRS 1013

Query: 1234 ERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPF 1293
            +  YKA GE+  H+Y +   LP+FI+AK NA N+S+  YK   ++L  +GY L  +A+P 
Sbjct: 1014 DIAYKAKGEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPI 1073

Query: 1294 QAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS 1353
            +AA+A+   ASD  Y+ D+ K +GK++G QS++DDP++ H   + ++QS+ +Y++    +
Sbjct: 1074 RAAKAARQAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKT 1133

Query: 1354 QAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYK 1413
            +++++ P DM ++V AK AQ + S+ +Y+   H +T LP+ + +  +K    +QS+  YK
Sbjct: 1134 KSKYNTPHDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYK 1193

Query: 1414 SDLIG-MKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSY 1472
             D    MKGIGW+ + S  +E  KKAG+ ++E KYR+ PD++KFT++VDSP +V AK + 
Sbjct: 1194 EDYNNWMKGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNT 1253

Query: 1473 MHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLD 1532
               ++ +Y++   +  H+YT+ PD P F +A+ NA ++SD  Y+  W    A   +   D
Sbjct: 1254 KQVSDILYKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWHDLIAKGNNVLGD 1313

Query: 1533 AIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKD 1592
            AIP   A+ASR IASD++YKEA+ + +G  +G+RS+ DDP++ H++NV +LQSD EYKK+
Sbjct: 1314 AIPITAAKASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKN 1373

Query: 1593 FAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSD 1652
            +  +++ +H+  D   +  AK +Q +A++V+Y+QPL   T  P+ + L H +  +Q+QSD
Sbjct: 1374 YENTKTSYHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSD 1433

Query: 1653 VKYKSDLN-LTRGVGWTPPGSYKVEMARRAAELANAR 1688
              YK + N   +G+GW P GS +VE  ++A +  N R
Sbjct: 1434 NVYKDEYNSFLKGIGWIPIGSLEVEKVKKAGDALNER 1470



 Score =  764 bits (1972), Expect = 0.0
 Identities = 493/1582 (31%), Positives = 817/1582 (51%), Gaps = 70/1582 (4%)

Query: 140  DPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHD 198
            DP+I+  +   K   + EY +D+E+ + + S P  +      AKK   L S V+YK    
Sbjct: 3300 DPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDML-GIVLAKKCQTLVSDVDYKHPLH 3358

Query: 199  ERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANEL 258
            E I     + D  +++ ++    LQSD  Y  D E  +G G  P       + AKRA EL
Sbjct: 3359 EWIC----LPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVR-AKRAGEL 3413

Query: 259  ASDVRYHQQYQK----------EMRGMAGPAIGAEGILTRECADQYGQG----------- 297
             SD  Y Q+ +           E       A+     L  E  D   +            
Sbjct: 3414 LSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIM 3473

Query: 298  -------------YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGA 344
                         Y    EE + +G    +     Q AK + ++ASD KY++ + K  G 
Sbjct: 3474 LAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGH 3533

Query: 345  AHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTS 404
             H  +   +D+  +  +  V K+ S+ EYKK+ E  +    +  +        K     S
Sbjct: 3534 -HIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVS 3592

Query: 405  DNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPS 464
            D  YK     H    +  +      + A K   L S+  YK+D     +++       P 
Sbjct: 3593 DIDYK-----HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSD-----LEWLRGIGWVPI 3642

Query: 465  YQTAMKLVP-----LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKN 519
                ++ V      L D  YRQ  D+LK++ +TDTP+IV AK NA  +S   Y   ++ +
Sbjct: 3643 GSVEVEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDAD 3702

Query: 520  KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELAS 579
            K +  +  D P ++ AK+N+   S+  Y +GW+++K K ++++ DA+S+ +AKAS ++AS
Sbjct: 3703 KTSIHVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIAS 3762

Query: 580  NIKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 635
            + KYKE YEK KG  +G      D +++ ++   K+ SE EYKK F++ KT+F  P+DM+
Sbjct: 3763 DYKYKEAYEKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDML 3822

Query: 636  NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 695
            +I  AKK QTL +D+DYR  LHE+T +P+      AKKAY LQS+  YKADL W++G+GW
Sbjct: 3823 SILLAKKCQTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGW 3882

Query: 696  LTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGN 755
            + +GS  + + K A  +  +  YR  V  LK+TS+ D+ ++  AK + E  S   Y+   
Sbjct: 3883 MPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVW 3942

Query: 756  EQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRD 815
            ++      I  D P    ARANA N+S KLY+  W+  KA G ++RLD++   AAKA R+
Sbjct: 3943 DKDKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASRE 4001

Query: 816  LASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSL 875
            +AS+ KYK D+E+ +G  +G    + D+++  +L   KLQ+E EY+  +   K++    +
Sbjct: 4002 IASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPV 4061

Query: 876  DMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKG 935
            DM+ ++H++ +Q L +D+ Y+   H +T +P    V  AKKAY LQSDN Y+AD++W++G
Sbjct: 4062 DMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRG 4121

Query: 936  MGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYR 995
            +GW+   S++V  AK A ++ SEKKYR   + L FT + D  + V A+ S     D  YR
Sbjct: 4122 IGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYR 4181

Query: 996  EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1055
            +     K  YT T + P +  A+  A  + +  YKE W + +  GY L  DA+PF  A  
Sbjct: 4182 KDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHH 4240

Query: 1056 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1115
              ++ S+ KYK    K KG  +G  ++ DD  L    +A  +Q++  YK+ +  +KA+ +
Sbjct: 4241 CNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKIN 4300

Query: 1116 LPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNF 1175
            +P DM +++ AK+ QTL S+ DY++ L Q+    +   +  A+KA+ LQS+N+YR+DL +
Sbjct: 4301 IPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEW 4360

Query: 1176 MRGVACVIPGTLEIEGRKKASELISESKYRQH--PHSFKYTAVTDTPNLLHAKFSNQITN 1233
            +RG+  +   +++     K  E++S+ KY+++   +   + +V D P ++ AK ++   +
Sbjct: 4361 LRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQS 4420

Query: 1234 ERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPF 1293
            +  YK     A+ +YT +   P    +K      S   YK +W   +A GY L    +P 
Sbjct: 4421 DVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPI 4480

Query: 1294 QAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS 1353
              A+ +  + S+  Y+  + K++G  +  + + + P + HC    +++S L YR+    +
Sbjct: 4481 VGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDT 4540

Query: 1354 QAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYK 1413
            +A  H+P DM++ V AK  Q + SD +YR  +H++T+L E+  +   + A  + S+  YK
Sbjct: 4541 KANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYK 4600

Query: 1414 SDLIGMKGIGWLALRSPQMESAKKAGELISETKYRK--KPDSIKFTTVVDSPDLVHAKNS 1471
             DL  +KGIG     +PQ+  AKK+ +L S+ +Y    K +   +  V D+P  V A  S
Sbjct: 4601 DDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQS 4660

Query: 1472 YMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRL 1531
             ++ +E  Y+    +   +YT + +  D+ R R      S  +Y+ +W++ +A SY    
Sbjct: 4661 GINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILPS 4720

Query: 1532 DAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKK 1591
              +    A+  + +AS  +Y+E + + + L    RSVDDDP     L VG+L  D  Y+ 
Sbjct: 4721 STLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRS 4780

Query: 1592 DFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQS 1651
             + K++ + H   D   ++ AK SQ+  S++ YR  L +  C P+     H +K     S
Sbjct: 4781 VYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQIS 4840

Query: 1652 DVKYKSDLNLTRGVG---WTPP 1670
            D+ YK DLN  +G+G   W  P
Sbjct: 4841 DIVYKDDLNWLKGIGCYVWDTP 4862



 Score =  730 bits (1885), Expect = 0.0
 Identities = 538/1840 (29%), Positives = 901/1840 (48%), Gaps = 183/1840 (9%)

Query: 38   MMLSVNNFVSHQKKPYCHAHNPKNNTFTSVYHTPLNL----NVRTFPEAISGIHDQEDGE 93
            M+L+ NN ++   + Y  A +    T   +  TP  L    N   + E +  +  +E   
Sbjct: 2708 MVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKLGLEEAKR 2767

Query: 94   QCKSVFHWDMK--SKDKEGAPNRQPLANERAYWTGYGEGNAWCPGALP---DPEIVRMVE 148
            +      +DM+  +   + A   + +A+E  Y  GY +      GA     DP+++  + 
Sbjct: 2768 K-----GYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWSMH 2822

Query: 149  ARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTV 207
              K   + EY +D+E+ + K S P  +      AKK   L S V+YK      + +++ +
Sbjct: 2823 VAKIQSDREYKKDFEKWKTKFSSPVDMLGVVL-AKKCQTLVSDVDYKN----YLHQWTCL 2877

Query: 208  VDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQ 267
             D  +++ ++    LQSD  Y  D +  RG G + ++ +   +  KRA E+ SD  Y Q 
Sbjct: 2878 PDQSDVIHARQAYDLQSDNMYKSDLQWMRGIG-WVSIGSLDVEKCKRATEILSDKIYRQP 2936

Query: 268  ---------------------------------YQKEMRGMAGPAIGAEGILTRECADQY 294
                                             + K+   +       E +L R+    Y
Sbjct: 2937 PDRFKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINY 2996

Query: 295  GQG-YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353
             +  Y    EE + KG            AK + ++ SD KY+  + K  G  H  +   +
Sbjct: 2997 SETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGH-HIGARNIE 3055

Query: 354  DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413
            D+  +  +  V K+ S+ EYKKD E  +    +  +        K     SD  YK NY 
Sbjct: 3056 DDPKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYK-NYL 3114

Query: 414  NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP 473
            +     +  +      +HA +   L S+  YK+D +        P       +       
Sbjct: 3115 HE----WTCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEI 3170

Query: 474  LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLV 533
            L D  YRQ  DKLK++SVTD+ + V AK NA  ++   Y   ++K+K    +  D P+++
Sbjct: 3171 LSDNIYRQPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIM 3230

Query: 534  KAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGK 593
             A+ N   +SE  Y++  E+ K +G++++ DA+ ++AAKAS ++AS+ KYKE Y K  G 
Sbjct: 3231 LARQNKINYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGH 3290

Query: 594  AMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASD 649
             +G      D +++ SL IAK+ S+ EYKK FE+ KTR+  P+DM+ I  AKK QTL SD
Sbjct: 3291 HIGARAVHDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSD 3350

Query: 650  LDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKA 709
            +DY+  LHE+  LP+      A+KAY LQS+  YK+DL WMKG+GW+   SL + +AK+A
Sbjct: 3351 VDYKHPLHEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRA 3410

Query: 710  GQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEP 769
            G+L+S+  YRQR + LKFTS+TD+ +   AK +    +   Y    +       +  D P
Sbjct: 3411 GELLSDTIYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTP 3470

Query: 770  LFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERS 829
              + A+ N  N S+KLYK + E  K +G++LRLD++   AAKA RD+AS+ KYKE Y + 
Sbjct: 3471 EIMLAKLNRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQ 3530

Query: 830  RGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHL 889
             G  IGA++++ D +M  S+ ++K+QS+ EYKK FE  K++    +DM+ +V A+K Q L
Sbjct: 3531 LGHHIGARNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQIL 3590

Query: 890  ATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQA 949
             +D+ YK   H +T LP    V  A+KAY LQSD  Y++D++W++G+GWV  GS+ VE+ 
Sbjct: 3591 VSDIDYKHPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKV 3650

Query: 950  KKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTA 1009
            K+AGE++S++KYRQ  D LKFT I DTPE+V A+ +       LY E  +  K       
Sbjct: 3651 KRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMP 3710

Query: 1010 DLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAF 1069
            D P++LLAK N+ NIS+  Y + W + +   Y LR DA+  ++AKAS +I SDYKYKEA+
Sbjct: 3711 DTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAY 3770

Query: 1070 EKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKA 1129
            EK KG  +G++S+EDD  +  +++A  +QS+  YKK F+  K +F  P+DM +++ AKK 
Sbjct: 3771 EKQKGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKC 3830

Query: 1130 QTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEI 1189
            QTL ++ DY++ L ++T + +   +  AKKA+ LQS+ LY++DL ++RG+  +  G+ E+
Sbjct: 3831 QTLVTDIDYRNYLHEWTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEV 3890

Query: 1190 EGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYT 1249
               K A  +  +S YR    + KYT++ DTP ++ AK + +  +   Y+   +  +    
Sbjct: 3891 LRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIH 3950

Query: 1250 MTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFL-- 1307
            +    PE   A+ NA N+S+  Y+E W  ++A G  + ++A+P QAA+AS +IASD+   
Sbjct: 3951 IMPDTPEINLARANALNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYK 4009

Query: 1308 ------------------------------------YRHDFVKERGKLIGPQSVR----- 1326
                                                YR D+ K + K+  P  +      
Sbjct: 4010 LDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHS 4069

Query: 1327 -----------------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1363
                                   D   +   ++  +LQS+  Y+      +    +P D 
Sbjct: 4070 KNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDS 4129

Query: 1364 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1421
            V + HAK+A  + S+  YRT+     FT + + +    AK++  +  +++Y+ D    K 
Sbjct: 4130 VSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKS 4189

Query: 1422 IGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCN----E 1477
              +    +P + +A++A  ++ +  Y++  +  K T  +  PD V   +++ HCN    E
Sbjct: 4190 -KYTLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH-HCNDVQSE 4247

Query: 1478 RMYRSGDAESLHRYTLIP---DHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAI 1534
              Y++   +    Y  +P   D P            ++++Y+  + +T+A   +   D +
Sbjct: 4248 LKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKA-KINIPADMV 4306

Query: 1535 PFQTARASREIASDFRYKEAF---------------LRDRGLQ--------------IGY 1565
                A+  + + SD  Y+                   +   LQ              IG+
Sbjct: 4307 SVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGW 4366

Query: 1566 RSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYR 1625
              +D    ++   N   + S  +YKK+  ++   F S  D P ++ AK +    SDV Y+
Sbjct: 4367 IPLDSVDHVRVTKNQ-EMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYK 4425

Query: 1626 QPLPQP----TCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1681
            +   +     T  P+   + H++   +L S + YK     T+  G+T    Y   +  + 
Sbjct: 4426 ETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKH 4485

Query: 1682 AELANARGLGLQGAYRGAEAVEAGDHQSGEVNPDATEILH 1721
            A+L N+     +  Y+     + G + +G+V  +   ++H
Sbjct: 4486 ADLVNS-----ELKYKETYEKQKGHYLAGKVIGEFPGVVH 4520



 Score =  590 bits (1522), Expect = e-168
 Identities = 442/1548 (28%), Positives = 737/1548 (47%), Gaps = 120/1548 (7%)

Query: 147  VEARKSLGEEYTE-DYEQPRGKGSFPAMI-TPAYQRAKKANQLASQVEYKRGHDERISRF 204
            VE  K  GE  ++  Y QP  +  F  +  TP    AK      S+  Y    D   +  
Sbjct: 3647 VEKVKRAGEILSDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSI 3706

Query: 205  STVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRY 264
              + DTP++L +K+ +   S   YT+ +++ + K         + + AK + ++ASD +Y
Sbjct: 3707 HVMPDTPDILLAKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKY 3766

Query: 265  HQQYQKEMRGMAGPAIGAEGILTRE---CADQYG-----QGYPEEYEEHRGKGSFPAMIT 316
             + Y+K+     G  IGA+ I       CA   G     + Y +E+++ + K S P  + 
Sbjct: 3767 KEAYEKQ----KGHHIGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDML 3822

Query: 317  PAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKD 376
             +   AKK   L +DI YR   ++      +  +P Q++++  QA+    L S+  YK D
Sbjct: 3823 -SILLAKKCQTLVTDIDYRNYLHE------WTCMPDQNDII--QAKKAYDLQSDALYKAD 3873

Query: 377  LESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG 436
            LE  RG       +P+   V                                        
Sbjct: 3874 LEWLRGIGWMPQGSPEVLRVKN-------------------------------------- 3895

Query: 437  SLASNVAYKADYKHDIVDYNYPATL-TPSYQTAMKLVP-LKDANYRQSIDKLKYS--SVT 492
              A N+   + Y+  +V+  Y + + TP    A      +    YR+  DK K S   + 
Sbjct: 3896 --AQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMP 3953

Query: 493  DTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWE 552
            DTP+I  A+ NA  +S+  YR  +++ K    +  D   +  AK + ++ S+ KYK   E
Sbjct: 3954 DTPEINLARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKASREIASDYKYKLDHE 4013

Query: 553  KTKGK--GFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLLHSLQIAK 610
            K KG   G     D   +  A  + +L +  +Y+ ++ K K                 AK
Sbjct: 4014 KQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWK-----------------AK 4056

Query: 611  MSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQW 670
            + S V                 DM++I H+K +Q L SD+DYR  LH++T +P+      
Sbjct: 4057 IQSPV-----------------DMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQ 4099

Query: 671  AKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSV 730
            AKKAY LQS+  YKADL W++G+GW+   S+++  AK A  + SEK YR +++ L FT V
Sbjct: 4100 AKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPV 4159

Query: 731  TDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSW 790
             D      AK+S E+   + Y+     +  +YT++ + PL   A+  A  L + LYK  W
Sbjct: 4160 DDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLT-ETPLLHTAQEAARILDQYLYKEGW 4218

Query: 791  ENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQ 850
            E QKA G+ L  D++ F+ A    D+ SE+KYK ++ + +G  +G   ++ D ++     
Sbjct: 4219 ERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEH 4278

Query: 851  MSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMK 910
              ++Q+E  YK+ +  TK++ ++  DMV ++ A++ Q L +D+ Y+   H +   P    
Sbjct: 4279 AGQIQNERLYKEDYHKTKAKINIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQND 4338

Query: 911  VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQH--PDAL 968
            V  A+KAY LQSDN YRAD++W++G+GW+   S++  +  K  E++S+ KY+++   +  
Sbjct: 4339 VIQARKAYDLQSDNVYRADLEWLRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALENYP 4398

Query: 969  KFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETR 1028
             F S+ D PE+V A+I+     D  Y+E     K  YT + D P +  +K      S   
Sbjct: 4399 NFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTIL 4458

Query: 1029 YKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISL 1088
            YK +W   +  GY L    +P   AK +  + S+ KYKE +EK KG  L  + + +   +
Sbjct: 4459 YKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGV 4518

Query: 1089 AHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSL 1148
             H +    ++S +NY+K +E +KA  H+P DM   V AK+ Q + S+ +Y+H   Q+TSL
Sbjct: 4519 VHCLDFQKMRSALNYRKHYEDTKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSL 4578

Query: 1149 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ-- 1206
             E+  +   + A ++ S+N+Y+ DLN+++G+ C +  T +I   KK+ +L S+ +Y    
Sbjct: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAG 4638

Query: 1207 HPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAAN 1266
              +   Y  VTDTP  + A  S    +E  YK      + +YT  L   ++ R +     
Sbjct: 4639 KENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNL 4698

Query: 1267 LSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVR 1326
             S   YKE+W  ++A  Y L    L    A+    +AS   YR ++ K +     P+SV 
Sbjct: 4699 YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVD 4758

Query: 1327 DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYH 1386
            DDP    C R+G+L  +  YR     ++ + H+  DMV +V AK++Q   S+ DYR + H
Sbjct: 4759 DDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLH 4818

Query: 1387 KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETK 1446
            ++   P+       +K     S++ YK DL  +KGIG     +P++  AK A +L  + K
Sbjct: 4819 EWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIK 4878

Query: 1447 YRKKPDSIK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH-RYTLIPDHPDFTRA 1503
            Y+      +  +  V D+P  V A  S    ++ +Y      S+  +        D  RA
Sbjct: 4879 YKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRA 4938

Query: 1504 RLNALHL-SDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQ 1562
             L+A  L S  +Y+ S      G Y    D   F+  + +R ++S F+YKEA+   +   
Sbjct: 4939 -LHAYKLQSSNLYKTSLRTLPTG-YRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKA-- 4994

Query: 1563 IGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDV 1622
             GY     D    H   V  + S+  Y++ + K + + H++ D P + Q K++Q+  S++
Sbjct: 4995 YGYTLGPKDVPFVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSEL 5054

Query: 1623 HYRQPL----PQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666
             Y+             P    + H +    + SD+KYK DL + +G G
Sbjct: 5055 IYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFG 5102



 Score =  514 bits (1325), Expect = e-145
 Identities = 435/1660 (26%), Positives = 744/1660 (44%), Gaps = 150/1660 (9%)

Query: 119  NERAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYT--EDYEQPRGK--GSFPAMI 174
            +++ Y  G+ E          D   ++  +A + +  +Y   E YE+ +G   G+     
Sbjct: 3726 SQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHHIGAQSIED 3785

Query: 175  TPAYQRAKKANQLASQVEYKRGHDERISRFSTVV-------------------------- 208
             P    A  A ++ S+ EYK+   +  ++FS+ V                          
Sbjct: 3786 DPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDIDYRNYLHE 3845

Query: 209  -----DTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFP--------------------- 242
                 D  +++++K    LQSD  Y  D E  RG G  P                     
Sbjct: 3846 WTCMPDQNDIIQAKKAYDLQSDALYKADLEWLRGIGWMPQGSPEVLRVKNAQNIFCDSVY 3905

Query: 243  -----------AMITPAYQIAKRANELASDVRYHQQYQKEMRGM-AGPAIGAEGILTREC 290
                        + TP   +AK   E  S  +Y + + K+   +   P      +     
Sbjct: 3906 RTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANA 3965

Query: 291  ADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHY-HS 349
             +   + Y E ++E +  G    +     Q AK + E+ASD KY+ D  K KG  HY  +
Sbjct: 3966 LNVSNKLYREGWDEMKA-GCDVRLDAIPIQAAKASREIASDYKYKLDHEKQKG--HYVGT 4022

Query: 350  LPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYK 409
            L A+D+  ++ A   +KL +E EY+ D    +    +  +     +        SD  Y+
Sbjct: 4023 LTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYR 4082

Query: 410  ENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK---------HDIVDYNYPAT 460
             NY +    ++  +      + A K   L S+  YKAD +         +D V  N+   
Sbjct: 4083 -NYLH----QWTCMPDQNDVIQAKKAYELQSDNVYKADLEWLRGIGWMPNDSVSVNHAKH 4137

Query: 461  LTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520
                +          +  YR  I+ L ++ V D    V AK + + L  + YR D+   K
Sbjct: 4138 AADIF---------SEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATK 4188

Query: 521  LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580
              YTL  + P L  A+  A++  +  YKEGWE+ K  G+ +  DA+  + A    ++ S 
Sbjct: 4189 SKYTL-TETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSE 4247

Query: 581  IKYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVN 636
            +KYK E+ K KG  +G      D +L+      ++ +E  YK+ + ++K + ++P DMV+
Sbjct: 4248 LKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKINIPADMVS 4307

Query: 637  IRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWL 696
            +  AK+ QTL SD+DYR  LH++   P+      A+KAY LQS+  Y+ADL W++G+GW+
Sbjct: 4308 VLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWI 4367

Query: 697  TEGSLNLEQAKKAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAKKSQELQSGVAYKAG 754
               S++  +  K  +++S+  Y++   E    F SV D  ++  AK +   QS V YK  
Sbjct: 4368 PLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKET 4427

Query: 755  NEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKR 814
              ++  +YT S D P    ++      S  LYK +WE  KA G+ L    +  + AK   
Sbjct: 4428 FNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHAD 4487

Query: 815  DLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVS 874
             + SE+KYKE YE+ +G  +  K +     + H L   K++S L Y+K +EDTK+  H+ 
Sbjct: 4488 LVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYEDTKANVHIP 4547

Query: 875  LDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMK 934
             DM++ V A++ Q++ +D+ Y+   H +T+L  +  V   + A  + SDN Y+ D+ W+K
Sbjct: 4548 NDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLK 4607

Query: 935  GMGWVATGSLNVEQAKKAGELISEKKYRQ--HPDALKFTSIKDTPEMVQARISYTQAVDR 992
            G+G     +  +  AKK+ +L S+ +Y      +   +  + DTP  V A  S   A + 
Sbjct: 4608 GIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEV 4667

Query: 993  LYREQGENIKHHYTPTADLPEVLLAKLNAMNI-SETRYKESWSKLRDGGYKLRLDALPFQ 1051
             Y+E    IK  YT   +  +    + N  N+ S   YKE+W +++   Y L    L   
Sbjct: 4668 KYKENYHQIKDKYTTVLETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYILPSSTLSLT 4726

Query: 1052 AAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSK 1111
             AK    + S  KY+E +EK K      RS++DD + A  +    L  D  Y+  +E +K
Sbjct: 4727 HAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNK 4786

Query: 1112 AQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRS 1171
             + H+  DM  +V AK +Q   S  DY+  L ++    +       +K     S+ +Y+ 
Sbjct: 4787 MKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKD 4846

Query: 1172 DLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNLLHAKFSN 1229
            DLN+++G+ C +  T EI   K A +L  + KY+ H    +  Y  VTDTP  + A  S 
Sbjct: 4847 DLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSG 4906

Query: 1230 QITNERLY------KAAGEDARHEYTMTLGLPEFIRA-KTNAANLSDARYKESWRNLRAQ 1282
            +  ++ +Y         G+ A    T T+ L   + A K  ++NL    YK S R L   
Sbjct: 4907 KQLSDAVYHYDYVHSVRGKVA--PTTKTVDLDRALHAYKLQSSNL----YKTSLRTL-PT 4959

Query: 1283 GYKLTIEALPFQAARASGDIASDFLYR--HDFVKERGKLIGPQSVRDDPRIQHCRRMGQL 1340
            GY+L  +   F+  + +  ++S F Y+  ++  K  G  +GP+    D    H RR+  +
Sbjct: 4960 GYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVHVRRVNNV 5015

Query: 1341 QSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK----FTALPEDLK 1396
             SE  YR      + + H   D   +   K  Q   S+  Y++ + K      +LP   +
Sbjct: 5016 TSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQ 5075

Query: 1397 MAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSI-- 1454
            +   +    + S+++YK DL  +KG G     +P M  ++   +L S   Y  K   +  
Sbjct: 5076 VIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRD 5135

Query: 1455 KFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRA----RLNALHL 1510
            K+  V+D+P+    +    H +E +YR+   +    +T +PD PD  RA    +L + +L
Sbjct: 5136 KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYL 5195

Query: 1511 SDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDD 1570
              ++         AG+    L     + A+  +++ S+ +YK   ++   ++  Y  V D
Sbjct: 5196 YVELATKERPHHHAGNQTTAL-----KHAKDVKDMVSEKKYK---IQYEKMKDKYTPVPD 5247

Query: 1571 DPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQ---- 1626
             P +          SD  YK+ F K++ ++H+  D   ++  ++     S + Y++    
Sbjct: 5248 TPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMS 5307

Query: 1627 PLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVG 1666
             L      P++    H +      SDVKYK DL   +G+G
Sbjct: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347



 Score =  441 bits (1133), Expect = e-123
 Identities = 435/1717 (25%), Positives = 739/1717 (43%), Gaps = 149/1717 (8%)

Query: 61   NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120
            N  +TS+  TP  +  ++  E IS    +E  ++ K+  H    + +   A       + 
Sbjct: 3911 NLKYTSIVDTPEVVLAKSNAENISIPKYREVWDKDKTSIHIMPDTPEINLARANALNVSN 3970

Query: 121  RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQR 180
            + Y  G+ E  A C   L D   ++  +A + +  +Y    +  + KG +   +T     
Sbjct: 3971 KLYREGWDEMKAGCDVRL-DAIPIQAAKASREIASDYKYKLDHEKQKGHYVGTLTARDDN 4029

Query: 181  ----AKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQR 236
                A  A++L ++ EY+    +  ++  + VD   +L SK    L SD+ Y     Q  
Sbjct: 4030 KIRWALIADKLQNEREYRLDWAKWKAKIQSPVDMLSILHSKNSQALVSDMDYRNYLHQWT 4089

Query: 237  GKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAG-PAIGAEGILTRECADQYG 295
                   +I      AK+A EL SD  Y    +  +RG+   P         +  AD + 
Sbjct: 4090 CMPDQNDVIQ-----AKKAYELQSDNVYKADLEW-LRGIGWMPNDSVSVNHAKHAADIFS 4143

Query: 296  QGYPEEYEEHRGKGSF-PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA-- 352
            +   ++Y       +F P      Y  AK++ E+  DIKYR+D+N  K        P   
Sbjct: 4144 E---KKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIKYRKDWNATKSKYTLTETPLLH 4200

Query: 353  -----------------------------QDNLVLKQAQSVNKLVSEVEYKKDLESSRGH 383
                                          D +    A   N + SE++YK +    +GH
Sbjct: 4201 TAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAHHCNDVQSELKYKAEHVKQKGH 4260

Query: 384  SINYCETPQFRNVSKISKFT------SDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVG- 436
               Y   P  R+  K+  F       ++  YKE+Y  H       +  D  ++ A K G 
Sbjct: 4261 ---YVGVPTMRDDPKLVWFEHAGQIQNERLYKEDY--HKTKAKINIPADMVSVLAAKQGQ 4315

Query: 437  SLASNVAYKADYKH---------DIV----------DYNYPATLTPSYQTAMKLVPLKDA 477
            +L S++ Y+ +Y H         D++          D  Y A L   +   +  +PL   
Sbjct: 4316 TLVSDIDYR-NYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADL--EWLRGIGWIPLDSV 4372

Query: 478  NY------RQSIDKLKYS-----------SVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520
            ++      ++ + ++KY            SV D P+IV AKIN+   S V Y+  + K K
Sbjct: 4373 DHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAK 4432

Query: 521  LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580
              YT   D P +  +K   KL+S + YK  WE TK  G+ +    + ++ AK +  + S 
Sbjct: 4433 GKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSE 4492

Query: 581  IKYKEEYEKTKG-----KAMGTADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMV 635
            +KYKE YEK KG     K +G     ++H L   KM S + Y+K +E++K   H+P DM+
Sbjct: 4493 LKYKETYEKQKGHYLAGKVIGEFPG-VVHCLDFQKMRSALNYRKHYEDTKANVHIPNDMM 4551

Query: 636  NIRHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGW 695
            N   AK+ Q + SDL+YR   H++T L E+      + A  + S+  YK DL W+KG+G 
Sbjct: 4552 NHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGC 4611

Query: 696  LTEGSLNLEQAKKAGQLVSEKNYRQRVDE--LKFTSVTDSSQMEHAKKSQELQSGVAYKA 753
                +  +  AKK+  L S+  Y     E    +  VTD+     A +S    S V YK 
Sbjct: 4612 YVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQSGINASEVKYKE 4671

Query: 754  GNEQSVHQYTISKDEPLFLQARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKA 812
               Q   +YT   +   + + R N  NL S  LYK +W+  KA  + L   +L+   AK 
Sbjct: 4672 NYHQIKDKYTTVLETVDYDRTR-NLKNLYSSNLYKEAWDRVKATSYILPSSTLSLTHAKN 4730

Query: 813  KRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCH 872
            ++ LAS +KY+E+YE+ +      + V  D   +  L++ KL  +  Y+  +E  K + H
Sbjct: 4731 QKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIH 4790

Query: 873  VSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKW 932
            +  DMV +V A+ +Q   +++ Y+   H +   P     +  +K     SD  Y+ D+ W
Sbjct: 4791 IVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNW 4850

Query: 933  MKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALK--FTSIKDTPEMVQARISYTQAV 990
            +KG+G     +  +  AK A +L  + KY+ H    +  +  + DTP  VQA  S  Q  
Sbjct: 4851 LKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLS 4910

Query: 991  DRLYR-EQGENIKHHYTP---TADLPEVLLA-KLNAMNISETRYKESWSKLRDGGYKLRL 1045
            D +Y  +   +++    P   T DL   L A KL + N+    YK S   L   GY+L  
Sbjct: 4911 DAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNL----YKTSLRTL-PTGYRLPG 4965

Query: 1046 DALPFQAAKASGEIISDYKYKEAFEKMK--GQMLGSRSLEDDISLAHSVYATSLQSDVNY 1103
            D   F+  K +  + S +KYKEA+E  K  G  LG +    D+   H     ++ S+  Y
Sbjct: 4966 DTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPK----DVPFVHVRRVNNVTSERLY 5021

Query: 1104 KKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPL----PQYTSLAEDLRLSCAKK 1159
            ++ +   K + H   D   +   KK Q   S   YK           SL    ++   + 
Sbjct: 5022 RELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRY 5081

Query: 1160 AHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSF--KYTAVT 1217
               + S+  Y+ DL  ++G  C +  T ++   +   +L S   Y         KY  V 
Sbjct: 5082 VGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVL 5141

Query: 1218 DTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWR 1277
            DTP     +      +E +Y+AAG+  +  +T     P+ +RAK      S   Y E   
Sbjct: 5142 DTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELAT 5201

Query: 1278 NLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRM 1337
              R   +    +    + A+   D+ S+  Y+  + K + K      V D P +   +R 
Sbjct: 5202 KERPH-HHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKY---TPVPDTPILIRAKRA 5257

Query: 1338 GQLQSELQYRRGATSSQAQFHLPMDMVHLVHAK----NAQALASDHDYRTQYHKFTALPE 1393
                S+L+Y+     ++ ++H   D + +V+ +    +   +    +Y +Q   + ++P+
Sbjct: 5258 YWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPD 5317

Query: 1394 DLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDS 1453
              +    +      S+++YK DL  +KGIG  A  +P    A+K   L S+ KY++  + 
Sbjct: 5318 RPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFER 5377

Query: 1454 IK--FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1511
             K  F  V DSP   H K +    NE+ YR+   +   +Y L+ D P    A+     +S
Sbjct: 5378 TKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQIS 5437

Query: 1512 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1571
               YR ++E+++             +T + +++I SD  YK  +  ++    GY ++ D 
Sbjct: 5438 QIKYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQI-SDILYKLEY--NKAKPRGYTTIHDT 5494

Query: 1572 PRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQP 1631
            P + H   V    SD +YK+ + +++S      D   +  AK + ++ +++ Y++     
Sbjct: 5495 PMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEAN 5554

Query: 1632 TC----DPEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1664
                   P++     A K+   QSD +YK D    +G
Sbjct: 5555 KAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKG 5591



 Score =  409 bits (1051), Expect = e-113
 Identities = 404/1636 (24%), Positives = 714/1636 (43%), Gaps = 200/1636 (12%)

Query: 141  PEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196
            P+   +++ARK+   +    Y  D E  RG G  P + +  + R  K  ++ SQ++YK+ 
Sbjct: 4334 PDQNDVIQARKAYDLQSDNVYRADLEWLRGIGWIP-LDSVDHVRVTKNQEMMSQIKYKKN 4392

Query: 197  HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRAN 256
              E    F +VVD PE++ +K  +  QSDV+Y E + + +GK +F +  TP    +K   
Sbjct: 4393 ALENYPNFRSVVDPPEIVLAKINSVNQSDVKYKETFNKAKGKYTF-SPDTPHISHSKDMG 4451

Query: 257  ELASDVRYH------QQYQKEMRGMAGPAIGAE--GILTRECADQYGQGYPEEYEEHRGK 308
            +L S + Y       + Y   +     P +GA+   ++  E        Y E YE+ +G 
Sbjct: 4452 KLYSTILYKGAWEGTKAYGYTLDERYIPIVGAKHADLVNSELK------YKETYEKQKGH 4505

Query: 309  -------GSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQA 361
                   G FP ++     +     ++ S + YR+ +   K   H  +    ++++ K+ 
Sbjct: 4506 YLAGKVIGEFPGVV-----HCLDFQKMRSALNYRKHYEDTKANVHIPN-DMMNHVLAKRC 4559

Query: 362  QSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYE 421
            Q +   +S++EY+           +  E P    V    +  SDN YK++  N ++G   
Sbjct: 4560 QYI---LSDLEYRHYFHQWT----SLLEEPNVIRVRNAQEILSDNVYKDDL-NWLKGIGC 4611

Query: 422  GVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVPLKDANYRQ 481
             V    + LHA K   L S + Y A  K ++ +YN   T TP Y TA             
Sbjct: 4612 YVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNL-VTDTPLYVTA------------- 4657

Query: 482  SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541
                            VQ+ INA   S V Y+ +Y + K  YT   +     + +    L
Sbjct: 4658 ----------------VQSGINA---SEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNL 4698

Query: 542  FSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTA--- 598
            +S   YKE W++ K   + +    +SL  AK    LAS+IKY+EEYEK K  A+ T    
Sbjct: 4699 YSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFK--ALYTLPRS 4756

Query: 599  ---DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK 655
               D      L++ K++ +  Y+  +E++K + H+  DMV +  AK +Q   S++DYR +
Sbjct: 4757 VDDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLR 4816

Query: 656  LHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSE 715
            LHE+   P+       +K     S++ YK DL W+KG+G     +  +  AK A  L  +
Sbjct: 4817 LHEWICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDD 4876

Query: 716  KNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQ 773
              Y+  + + +  +  VTD+     A KS +  S   Y      SV        + + L 
Sbjct: 4877 IKYKAHMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLD 4936

Query: 774  ARANAANL-SEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSR-- 830
               +A  L S  LYK+S       G+ L  D+  F   K  R ++S  KYKE YE ++  
Sbjct: 4937 RALHAYKLQSSNLYKTSLRTLPT-GYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAY 4995

Query: 831  GKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLA 890
            G  +G KDV       H  +++ + SE  Y++ +   K + H + D   +   +K Q   
Sbjct: 4996 GYTLGPKDVP----FVHVRRVNNVTSERLYRELYHKLKDKIHTTPDTPEIRQVKKTQEAV 5051

Query: 891  TDVGYKT----AEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNV 946
            +++ YK+     + H  +LP   +V   +    + SD +Y+ D++ +KG G     + ++
Sbjct: 5052 SELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDM 5111

Query: 947  EQAKKAGELISEKKYRQHPDAL--KFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH 1004
             +++   +L S   Y      +  K+  + DTPE  + +   T   + +YR  G+  K  
Sbjct: 5112 VRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSI 5171

Query: 1005 YTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYK 1064
            +T   D P++L AK      S+  Y E  +K R   +         + AK   +++S+ K
Sbjct: 5172 FTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKK 5230

Query: 1065 YKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALV 1124
            YK  +EKMK +      + D   L  +  A    SD+ YK+ F+ +K ++H   D   +V
Sbjct: 5231 YKIQYEKMKDKYT---PVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIV 5287

Query: 1125 HAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENL----YRSDLNFMRGVA 1180
            + +K     S   YK        +   +        H+  ++ +    Y+ DL +++G+ 
Sbjct: 5288 YHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIG 5347

Query: 1181 CVIPGTLEIEGRKKASELISESKYRQ----HPHSFKYTAVTDTPNLLHAKFSNQITNERL 1236
            C    T +    +K   L S+ KY++        FKY A  D+P   H K++ Q+ NE+ 
Sbjct: 5348 CYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVA--DSPINRHFKYATQLMNEKK 5405

Query: 1237 YKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAA 1296
            Y+A  E  + +Y + +  P  + AKT    +S  +Y++++   + +   +       +  
Sbjct: 5406 YRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHLRTT 5465

Query: 1297 RASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ 1356
            + +  I SD LY+ ++ K + +  G  ++ D P + H R++    S+L+Y+     +++ 
Sbjct: 5466 KVNKQI-SDILYKLEYNKAKPR--GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSN 5522

Query: 1357 FHLPMDMVHLVHAKNAQALASDHDYRTQYHKFTA----LPEDLKMAWAKKAHALQSELRY 1412
              +  D VH+  AK+A  + ++ DY+ QY    A     P+      A K+   QS+  Y
Sbjct: 5523 CTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEY 5582

Query: 1413 KSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFT--TVVDSPDLVHAKN 1470
            K D   +KG             A +   + S+ KY++K    + T   V D+P ++ AK 
Sbjct: 5583 KLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKT 5642

Query: 1471 SYMHCNERMYRSGDAESLHR--YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYD 1528
                 +E  Y+    + L +  YT +P+  D    +    H+SD                
Sbjct: 5643 VSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDT--------------- 5687

Query: 1529 FRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNE 1588
                                  YK+ F++++G +  Y  + + P +KH + V + QSD  
Sbjct: 5688 ---------------------NYKKKFVKEKG-KSNYSIMLEPPEVKHAMEVAKKQSDVA 5725

Query: 1589 YKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQ 1648
            Y+KD AK    + +  D+P + +A ++ + AS+V YR               +H ++   
Sbjct: 5726 YRKD-AKENLHYTTVADRPDIKKATQAAKQASEVEYRA--------------KHRKEGSH 5770

Query: 1649 LQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANARGLGLQGAYRGAEAVEAGDHQ 1708
                             G +  G   +EMA++AA+L++      Q  YR     E G  +
Sbjct: 5771 -----------------GLSMLGRPDIEMAKKAAKLSS------QVKYRENFDKEKG--K 5805

Query: 1709 SGEVNPDATEILHVKK 1724
            + + NP  +++  V K
Sbjct: 5806 TPKYNPKDSQLYKVMK 5821



 Score =  351 bits (900), Expect = 4e-96
 Identities = 399/1631 (24%), Positives = 699/1631 (42%), Gaps = 140/1631 (8%)

Query: 138  LPDPEIVRMVEARKSLGEE-YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRG 196
            L +P ++R+  A++ L +  Y +D    +G G +    TP    AKK+  L SQ++Y   
Sbjct: 4579 LEEPNVIRVRNAQEILSDNVYKDDLNWLKGIGCY-VWDTPQILHAKKSYDLQSQLQYTAA 4637

Query: 197  HDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF--------------- 241
              E +  ++ V DTP  + +       S+V+Y E+Y Q + K +                
Sbjct: 4638 GKENLQNYNLVTDTPLYVTAVQSGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKN 4697

Query: 242  ----------------PAMITPAYQI----AKRANELASDVRYHQQYQKEMRGMAGPAIG 281
                             + I P+  +    AK    LAS ++Y ++Y+K       P   
Sbjct: 4698 LYSSNLYKEAWDRVKATSYILPSSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSV 4757

Query: 282  AEGILTRECAD----QYGQGYPEEYEEHRGK-GSFPAMITPAYQNAKKAHELASDIKYRQ 336
             +   T  C         + Y   YE+++ K    P M+      AK + +  S+I YR 
Sbjct: 4758 DDDPNTARCLRVGKLNIDRLYRSVYEKNKMKIHIVPDMVEMV--TAKDSQKKVSEIDYRL 4815

Query: 337  DFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNV 396
              ++         +   D  V    + V   +S++ YK DL   +G      +TP+  + 
Sbjct: 4816 RLHEW--------ICHPDLQVNDHVRKVTDQISDIVYKDDLNWLKGIGCYVWDTPEILHA 4867

Query: 397  SKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYN 456
                    D KYK  +    R  Y+ V      + A+K G   S+  Y  DY H +    
Sbjct: 4868 KHAYDLRDDIKYKA-HMLKTRNDYKLVTDTPVYVQAVKSGKQLSDAVYHYDYVHSVRGKV 4926

Query: 457  YPATLTPSYQTAMKLVPLKDAN-YRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYR 513
             P T T     A+    L+ +N Y+ S+  L   Y    DTP     K      S+  Y+
Sbjct: 4927 APTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGDTPHFKHIKDTRYMSSYFKYK 4986

Query: 514  ADYEKNK-LNYTL-PQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAA 571
              YE  K   YTL P+DVP +   + N  + SE  Y+E + K K K      D   +   
Sbjct: 4987 EAYEHTKAYGYTLGPKDVPFVHVRRVN-NVTSERLYRELYHKLKDK-IHTTPDTPEIRQV 5044

Query: 572  KASGELASNIKYKEEYEKTKGKAMGTA-DSRLLHSLQIAKMSSEVEYKKGFEESK---TR 627
            K + E  S + YK ++ K +G  +      +++H   +  ++S+++YK+  +  K     
Sbjct: 5045 KKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQVLKGFGCF 5104

Query: 628  FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE-YTVL---PEDMKTQWAKKAYGLQSELQY 683
             +   DMV  RH +K  +     D  +K+ + Y V+   PE  K Q  K      SEL Y
Sbjct: 5105 LYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPEYRKVQELKTHL---SELVY 5161

Query: 684  KADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELK--FTSVTDSSQMEHAKK 741
            +A     K +      + +L +AK+  +L S+  Y +   + +    +   ++ ++HAK 
Sbjct: 5162 RAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKERPHHHAGNQTTALKHAKD 5221

Query: 742  SQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELR 801
             +++ S   YK   E+   +YT   D P+ ++A+    N S+  YK +++  K K   ++
Sbjct: 5222 VKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQKTKGKYHTVK 5281

Query: 802  LDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYK 861
             D+L  +  +   D  S++KYKE+Y    G     + +    +  H   ++   S+++YK
Sbjct: 5282 -DALDIVYHRKVTDDISKIKYKENYMSQLGIW---RSIPDRPEHFHHRAVTDTVSDVKYK 5337

Query: 862  KGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKV-------EWA 914
            +     K     + D      A K + L +   YK     F    +D K           
Sbjct: 5338 EDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEV---FERTKSDFKYVADSPINRHF 5394

Query: 915  KKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDAL--KFTS 972
            K A  L ++ +YRAD +  K    +         AK AG+ IS+ KYR++ +    KFTS
Sbjct: 5395 KYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTS 5454

Query: 973  IKDTPEMVQARISYTQAVDRLYREQGENIK-HHYTPTADLPEVLLAKLNAMNISETRYKE 1031
            I DTPE ++      Q  D LY+ +    K   YT   D P +L  +     +S+ +YKE
Sbjct: 5455 IVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKE 5514

Query: 1032 SWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHS 1091
             + +       +  DA+  +AAK + ++ ++  YK+ +E  K     +    D +  A S
Sbjct: 5515 VYQR-NKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQAAKS 5573

Query: 1092 VYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDY--KHPLPQYT--S 1147
               +  QSD  YK   E  K       D    V A +   + S+  Y  KH   + T  +
Sbjct: 5574 ---SLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKEKHVKERGTCHA 5630

Query: 1148 LAEDLRLSCAKKAHKLQSENLYRSDL--NFMRGVACVIPGTLEIEGRKKASELISESKYR 1205
            + +  ++  AK    L SEN Y+  +  +  +G    +P T +    K+ ++ +S++ Y+
Sbjct: 5631 VPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYK 5690

Query: 1206 ----QHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAK 1261
                +      Y+ + + P + HA    +  ++  Y+   ++  H YT     P+  +A 
Sbjct: 5691 KKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLH-YTTVADRPDIKKAT 5749

Query: 1262 TNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERGKLIG 1321
              A   S+  Y+   R   + G  + +     + A+ +  ++S   YR +F KE+GK   
Sbjct: 5750 QAAKQASEVEYRAKHRKEGSHGLSM-LGRPDIEMAKKAAKLSSQVKYRENFDKEKGK-TP 5807

Query: 1322 PQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPM----DMVHLVHAKNAQALAS 1377
              + +D    +  +    L SE++Y+    +   + H P+    + + + H  N   LAS
Sbjct: 5808 KYNPKDSQLYKVMKDANNLASEVKYK----ADLKKLHKPVTDMKESLIMNHVLNTSQLAS 5863

Query: 1378 DHDYRTQYHK----FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQME 1433
             + Y+ +Y K    +  +P++L+    K+A  LQS ++YK      +G   L   +P   
Sbjct: 5864 SYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYI 5923

Query: 1434 SAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLH 1489
            +AK++ ++ S  +YRK   +SIK    T +  +P L+H K +    +E+ YR    ES+ 
Sbjct: 5924 TAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIR 5983

Query: 1490 --RYTLIPDHPDFTRARLNALHLSDKVYRNSWE-QTRAGSYDFRLDAIP-FQTARASREI 1545
                T + D PD  RA+     L++K Y+   E + +    +   +  P F  AR + +I
Sbjct: 5984 GKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDI 6043

Query: 1546 ASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTD 1605
            AS  +YK++   ++     + SV D P + H   V  L S  +YK+D  KS S + +  D
Sbjct: 6044 ASQIKYKQSAEMEKA---NFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLD 6100

Query: 1606 QPGLLQAKRSQQLASDVHYRQPLPQP-------TCDPEQLGLRHAQKAHQLQSDVKYKSD 1658
             P + + + +Q+  S + Y+  L             PE L ++  QK     S V YK D
Sbjct: 6101 TPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNF---SSVLYKED 6157

Query: 1659 LNLTRGVGWTP 1669
            ++    +G TP
Sbjct: 6158 VSPGTAIGKTP 6168



 Score =  336 bits (862), Expect = 1e-91
 Identities = 386/1671 (23%), Positives = 688/1671 (41%), Gaps = 196/1671 (11%)

Query: 141  PEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQ---RAKKANQLASQVEYKRGH 197
            P++V MV A+ S  +    DY     +     +  P  Q     +K     S + YK   
Sbjct: 4793 PDMVEMVTAKDSQKKVSEIDYRLRLHEW----ICHPDLQVNDHVRKVTDQISDIVYKDDL 4848

Query: 198  DERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANE 257
            +        V DTPE+L +K    L+ D++Y     + R         TP Y  A ++ +
Sbjct: 4849 NWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKL-VTDTPVYVQAVKSGK 4907

Query: 258  LASDVRYHQQYQKEMRGMAGPAIGAEGI------LTRECADQYGQGYPEEYEEHRGKGSF 311
              SD  YH  Y   +RG   P      +         + ++ Y          +R  G  
Sbjct: 4908 QLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPTGYRLPGD- 4966

Query: 312  PAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371
                TP +++ K    ++S  KY++ +   K  A+ ++L  +D +     + VN + SE 
Sbjct: 4967 ----TPHFKHIKDTRYMSSYFKYKEAYEHTK--AYGYTLGPKD-VPFVHVRRVNNVTSER 5019

Query: 372  EYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLH 431
             Y++     +       +TP+ R V K  +  S+  YK ++   M+G    +    + +H
Sbjct: 5020 LYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFK-MQGHMISLPYTPQVIH 5078

Query: 432  AMKVGSLASNVAYKADYK------------HDIVDYNYPATLTPSYQTAMKLVPLKDANY 479
               VG + S++ YK D +             D+V   +   L  +Y    K   ++D   
Sbjct: 5079 CRYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRD--- 5135

Query: 480  RQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNA 539
                   KY  V DTP+  + +     LS + YRA  +K K  +T   D P L++AK   
Sbjct: 5136 -------KYKVVLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQ 5188

Query: 540  KLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMGTAD 599
            KL S+  Y E   K +           +L  AK   ++ S  KYK +YEK K K     D
Sbjct: 5189 KLQSQYLYVELATKERPHHHAGN-QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPD 5247

Query: 600  SRLLHSLQIAKMS-SEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRK---- 654
            + +L   + A  + S++ YK+ F+++K ++H   D ++I + +K     S + Y++    
Sbjct: 5248 TPILIRAKRAYWNASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMS 5307

Query: 655  KLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS 714
            +L  +  +P+  +    +      S+++YK DL W+KG+G     + +   A+K   L S
Sbjct: 5308 QLGIWRSIPDRPEHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYS 5367

Query: 715  EKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFL 772
            +  Y++  +  K  F  V DS    H K + +L +   Y+A  EQ   +Y +  DEP  L
Sbjct: 5368 KYKYKEVFERTKSDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHL 5427

Query: 773  QARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGK 832
             A+     +S+  Y+ ++E  K K F   +D+   L         S++ YK +Y +++ +
Sbjct: 5428 LAKTAGDQISQIKYRKNYEKSKDK-FTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPR 5486

Query: 833  LIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATD 892
              G   +     + H  ++    S+L+YK+ ++  KS C +  D VH+  A+ A  + T+
Sbjct: 5487 --GYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTN 5544

Query: 893  VGYKTA----EHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLN--- 945
            + YK      + H+   P       A K+   QSD +Y+ D +++KG     T   N   
Sbjct: 5545 LDYKKQYEANKAHWKWTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVL 5604

Query: 946  --------------------------------VEQAKKAGELISEKKYRQHPDAL----K 969
                                            +  AK    L+SE KY+ H         
Sbjct: 5605 ALRNTLIESDLKYKEKHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGS 5664

Query: 970  FTSIKDTPEMVQAR-----ISYTQAVDRLYREQGEN----------IKH----------- 1003
            +T++ +T + V  +     +S T    +  +E+G++          +KH           
Sbjct: 5665 YTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDV 5724

Query: 1004 ----------HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALP-FQA 1052
                      HYT  AD P++  A   A   SE  Y+    K  +G + L +   P  + 
Sbjct: 5725 AYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRK--EGSHGLSMLGRPDIEM 5782

Query: 1053 AKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKA 1112
            AK + ++ S  KY+E F+K KG+       +  +       A +L S+V YK   +    
Sbjct: 5783 AKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQLYKVMKD-ANNLASEVKYKADLK---- 5837

Query: 1113 QFHLPL----DMAALVHAKKAQTLASNQDYKHPLPQ----YTSLAEDLRLSCAKKAHKLQ 1164
            + H P+    +   + H      LAS+  YK    +    Y ++ ++L     K+A +LQ
Sbjct: 5838 KLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQ 5897

Query: 1165 SENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ-HPHSFK---YTAVTDTP 1220
            S   Y+      RG   +   T      K++ ++ S  +YR+ +  S K    T +  TP
Sbjct: 5898 SIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTP 5957

Query: 1221 NLLHAKFSNQITNERLYKAAGEDARHEYTMTL--GLPEFIRAKTNAANLSDARYKESWR- 1277
             LLH K++ +I +E+ Y+   E++     +T     P+ +RAK     L++  YK     
Sbjct: 5958 ALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLEL 6017

Query: 1278 NLRAQGYKLTIEALP-FQAARASGDIASDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRR 1336
             ++ +G        P F  AR + DIAS   Y+     E+       SV D P I H ++
Sbjct: 6018 EVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFT---SVVDTPEIIHAQQ 6074

Query: 1337 MGQLQSELQYRRGATSSQAQFHLPMDMVHLVHA----KNAQALASDHDYRTQYHKFTALP 1392
            +  L S+ +Y+  A  S + +   +D   +       KN   L    D +    K T + 
Sbjct: 6075 VKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQ 6134

Query: 1393 EDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPD 1452
            +  ++   K+     S + YK D+     IG    ++P+M   K+  + IS  KY++   
Sbjct: 6135 DTPEILRVKENQKNFSSVLYKEDVSPGTAIG----KTPEMMRVKQTQDHISSVKYKEAIG 6190

Query: 1453 SIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSD 1512
              + T + D P++   K +  H +  MY+    E+L         P+  R + N  + S 
Sbjct: 6191 --QGTPIPDLPEVKRVKETQKHISSVMYK----ENLGTGIPTTVTPEIERVKRNQENFSS 6244

Query: 1513 KVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDP 1572
             +Y+ +  +         ++ +     + ++E  S   YKE   +   L +        P
Sbjct: 6245 VLYKENLGKGIPTPITPEMERV-----KRNQENFSSVLYKENMGKGTPLAV-------TP 6292

Query: 1573 RMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPT 1632
             M+   +     S   YK++  K+ +    +   P + + KR+Q+  S V Y++ L + T
Sbjct: 6293 EMERVKHNQENISSVLYKENVGKATA----TPVTPEMQRVKRNQENISSVLYKENLGKAT 6348

Query: 1633 CDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAE 1683
              P    +   ++  +  S V YK ++        TP    ++E A+R  E
Sbjct: 6349 PTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTP----EMERAKRNQE 6395



 Score =  295 bits (755), Expect = 3e-79
 Identities = 377/1606 (23%), Positives = 660/1606 (41%), Gaps = 155/1606 (9%)

Query: 175  TPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQ 234
            TP  ++ KK  +  S++ YK    +      ++  TP+++  +    + SD++Y ED + 
Sbjct: 5038 TPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHCRYVGDITSDIKYKEDLQV 5097

Query: 235  QRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQY 294
             +G G F    TP    ++   +L S+  Y  + +K MR      +        +    +
Sbjct: 5098 LKGFGCF-LYDTPDMVRSRHLRKLWSNYLYTDKARK-MRDKYKVVLDTPEYRKVQELKTH 5155

Query: 295  GQGYPEEYEEHRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQ 353
                       + K  F ++  TP    AK+  +L S   Y +   K +   H+H+    
Sbjct: 5156 LSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVELATKER--PHHHA--GN 5211

Query: 354  DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQ 413
                LK A+ V  +VSE +YK   E  +       +TP      +     SD +YKE +Q
Sbjct: 5212 QTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYWNASDLRYKETFQ 5271

Query: 414  NHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMKLVP 473
               +G+Y  V      ++  KV    S + YK +Y   +  +         +        
Sbjct: 5272 K-TKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRPEHFHHRAVTDT 5330

Query: 474  LKDANYRQSIDKLKYSS--VTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQ 531
            + D  Y++ +  LK       DTP    A+ N    S   Y+  +E+ K ++    D P 
Sbjct: 5331 VSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTKSDFKYVADSPI 5390

Query: 532  LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591
                K   +L +E KY+  +E+ K K + + +D    L AK +G+  S IKY++ YEK+K
Sbjct: 5391 NRHFKYATQLMNEKKYRADYEQRKDK-YHLVVDEPRHLLAKTAGDQISQIKYRKNYEKSK 5449

Query: 592  GKAMGTADS-RLLHSLQIAKMSSEVEYKKGFEESKTRFHLPM-DMVNIRHAKKAQTLASD 649
             K     D+   L + ++ K  S++ YK  + ++K R +  + D   + H +K +   SD
Sbjct: 5450 DKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSD 5509

Query: 650  LDYR----KKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQ 705
            L Y+    +     T+ P+ +  + AK AY + + L YK      K     T    +  Q
Sbjct: 5510 LKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKWTPDRPDFLQ 5569

Query: 706  AKKAGQLVSEKNYRQRVDELKFT--SVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYT 763
            A K+    S+  Y+   + LK    SVTD      A ++  ++S + YK   E+ V +  
Sbjct: 5570 AAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYK---EKHVKERG 5626

Query: 764  ISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 823
                 P                                 D+   L AK   +L SE KYK
Sbjct: 5627 TCHAVP---------------------------------DTPQILLAKTVSNLVSENKYK 5653

Query: 824  EDYERSRGKLIGAKDVQGDSQMS-HSLQMSKLQSELEYKKGF--EDTKSQCHVSLDMVHL 880
            +  ++   +  G+     +++ + H  +++K  S+  YKK F  E  KS   + L+   +
Sbjct: 5654 DHVKKHLAQ--GSYTTLPETRDTVHVKEVTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEV 5711

Query: 881  VHARKAQHLATDVGY-KTAEH--HFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMG 937
             HA +     +DV Y K A+   H+T +     ++ A +A    S+ +YRA  +     G
Sbjct: 5712 KHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQASEVEYRAKHRKEGSHG 5771

Query: 938  WVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYRE- 996
                G  ++E AKKA +L S+ KYR++ D  K  + K  P+  Q      +  + L  E 
Sbjct: 5772 LSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDSQL-YKVMKDANNLASEV 5830

Query: 997  -QGENIKHHYTPTADLPEVLLAK--LNAMNISET-RYKESWSKLRDGGYKLRLDALPFQA 1052
                ++K  + P  D+ E L+    LN   ++ + +YK+ + K + G Y    D L    
Sbjct: 5831 KYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKSK-GHYHTIPDNLEQLH 5889

Query: 1053 AKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS-K 1111
             K + E+ S  KYKE +EK +G+ +        I+   S     +QS   Y+K +E S K
Sbjct: 5890 LKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKES---QQMQSGKEYRKDYEESIK 5946

Query: 1112 AQFHLPLDMA-ALVHAKKAQTLASNQDYKHPLPQ------YTSLAEDLRLSCAKKAHKLQ 1164
             +    L++  AL+H K A  +AS ++Y+  L +       T + +   +  AK A ++ 
Sbjct: 5947 GRNLTGLEVTPALLHVKYATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQIL 6006

Query: 1165 SENLYRSDLNFM---RGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDT 1219
            +E  Y+ DL      RG+  +   T +    + A+++ S+ KY+Q     K  +T+V DT
Sbjct: 6007 NEKEYKRDLELEVKGRGLNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDT 6066

Query: 1220 PNLLHAKFSNQITNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNL 1279
            P ++HA+    +++++ YK   E +   Y   L  PE  R + N  N S  +Y+   +N 
Sbjct: 6067 PEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNS 6126

Query: 1280 RAQGYKLTI--EALPFQAARASGDIASDFLYRHDFVKERGKLIG--PQSVR--------- 1326
            +    K+T+  +       + +    S  LY+ D     G  IG  P+ +R         
Sbjct: 6127 KG---KITVVQDTPEILRVKENQKNFSSVLYKEDV--SPGTAIGKTPEMMRVKQTQDHIS 6181

Query: 1327 ---------------DDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKN 1371
                           D P ++  +   +  S + Y+    +       P     +   K 
Sbjct: 6182 SVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTP----EIERVKR 6237

Query: 1372 AQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1431
             Q   S   Y+    K    P   +M   K+     S + YK ++    G G     +P+
Sbjct: 6238 NQENFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSVLYKENM----GKGTPLAVTPE 6293

Query: 1432 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1491
            ME  K   E IS   Y++       T V  +P++   K +  + +  +Y+    E+L + 
Sbjct: 6294 MERVKHNQENISSVLYKENVGKATATPV--TPEMQRVKRNQENISSVLYK----ENLGKA 6347

Query: 1492 TLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRY 1551
            T  P  P+  R + N  + S  +Y+ +  +         ++      A+ ++E  S   Y
Sbjct: 6348 TPTPFTPEMERVKRNQENFSSVLYKENMRKATPTPVTPEMER-----AKRNQENISSVLY 6402

Query: 1552 KEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQ 1611
             ++F +    +  Y  V D P M+      R  S  +Y +DF K +  F      P   +
Sbjct: 6403 SDSFRKQIQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITER 6460

Query: 1612 AKRSQQLASDVHYR------QPLPQPTCDPEQ---LGLRHAQKAHQLQSDVKYKSDLNLT 1662
             K++ Q  SD++YR        + Q   D +Q    GLR  +       D     D   +
Sbjct: 6461 VKKNMQDFSDINYRGIQRKVVEMEQKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQS 6520

Query: 1663 RGVGWTPPGSYKVEMARRAAELA-NARGLGLQGAYRGAEAVEAGDH 1707
            R +         V+  RR+ E + +A  L + G    +E  EA DH
Sbjct: 6521 RSL-----HMINVQAQRRSREQSRSASALSISGGEEKSEHSEAPDH 6561



 Score =  264 bits (674), Expect = 6e-70
 Identities = 281/1147 (24%), Positives = 488/1147 (42%), Gaps = 133/1147 (11%)

Query: 155  EEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISRFSTVVDTPELL 214
            ++Y  DYEQ + K     +  P +  AK A    SQ++Y++ +++   +F+++VDTPE L
Sbjct: 5404 KKYRADYEQRKDKYHL-VVDEPRHLLAKTAGDQISQIKYRKNYEKSKDKFTSIVDTPEHL 5462

Query: 215  RSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRG 274
            R+    +  SD+ Y  +Y + + +G      TP     ++  +  SD++Y + YQ   R 
Sbjct: 5463 RTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLHVRKVKDEVSDLKYKEVYQ---RN 5519

Query: 275  MAGPAIGAEGILTRECADQY----GQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELAS 330
             +   I  + +  +   D Y       Y ++YE ++    +     P +  A K+    S
Sbjct: 5520 KSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWKW-TPDRPDFLQAAKSSLQQS 5578

Query: 331  DIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCET 390
            D +Y+ D   +KG     S+    N VL    ++  + S+++YK+     RG      +T
Sbjct: 5579 DFEYKLDREFLKGCK--LSVTDDKNTVLALRNTL--IESDLKYKEKHVKERGTCHAVPDT 5634

Query: 391  PQFRNVSKISKFTSDNKYKENYQNHM-RGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK 449
            PQ      +S   S+NKYK++ + H+ +G Y  +   R T+H  +V    S+  YK  + 
Sbjct: 5635 PQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKEVTKHVSDTNYKKKFV 5694

Query: 450  HDIVDYNYPATL-TPSYQTAMKLVPLK-DANYRQSI-DKLKYSSVTDTPQIVQAKINAQQ 506
             +    NY   L  P  + AM++   + D  YR+   + L Y++V D P I +A   A+Q
Sbjct: 5695 KEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTVADRPDIKKATQAAKQ 5754

Query: 507  LSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMK-LDA 565
             S V YRA + K   +       P +  AK  AKL S+VKY+E ++K KGK  +    D+
Sbjct: 5755 ASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENFDKEKGKTPKYNPKDS 5814

Query: 566  MSLLAAKASGELASNIKYKEEYEKTKGKAMGTADSRLL-HSLQIAKMSSEVEYKKGFEES 624
                  K +  LAS +KYK + +K         +S ++ H L  ++++S  +YKK +E+S
Sbjct: 5815 QLYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTSQLASSYQYKKKYEKS 5874

Query: 625  KTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPE-DMKTQ---WAKKAYGLQSE 680
            K  +H   D +   H K+A  L S + Y++K  +    P  D +T     AK++  +QS 
Sbjct: 5875 KGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFETPTYITAKESQQMQSG 5934

Query: 681  LQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 740
             +Y+                               K+Y + +     T +  +  + H K
Sbjct: 5935 KEYR-------------------------------KDYEESIKGRNLTGLEVTPALLHVK 5963

Query: 741  KSQELQSGVAYKAGNEQSVH--QYTISKDEPLFLQARANAANLSEKLYKSSWENQ-KAKG 797
             + ++ S   Y+   E+S+     T  +D P  L+A+     L+EK YK   E + K +G
Sbjct: 5964 YATKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRG 6023

Query: 798  FE-LRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQS 856
               +  ++  F+ A+   D+AS++KYK+  E  +       D     ++ H+ Q+  L S
Sbjct: 6024 LNAMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDT---PEIIHAQQVKNLSS 6080

Query: 857  ELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKK 916
            + +YK+  E + S     LD   +   R+ Q             +F+ L           
Sbjct: 6081 QKKYKEDAEKSMSYYETVLDTPEIQRVRENQ------------KNFSLL----------- 6117

Query: 917  AYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDT 976
                    QY+ D+K  KG   V   +  + + K+  +  S   Y++  D    T+I  T
Sbjct: 6118 --------QYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKE--DVSPGTAIGKT 6167

Query: 977  PEMVQARISYTQAVDRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKL 1036
            PEM++ +    Q  D +   + +      TP  DLPEV   K    +IS   YKE+    
Sbjct: 6168 PEMMRVK----QTQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKENL--- 6220

Query: 1037 RDGGYKLRLDALP-FQAAKASGEIISDYKYKEAFEK-----MKGQMLGSRSLEDDISLAH 1090
               G  +     P  +  K + E  S   YKE   K     +  +M   +  +++     
Sbjct: 6221 ---GTGIPTTVTPEIERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQENF---- 6273

Query: 1091 SVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAE 1150
                    S V YK+           P     +   K  Q   S+  YK  + + T+   
Sbjct: 6274 --------SSVLYKENMGKGTPLAVTP----EMERVKHNQENISSVLYKENVGKATATPV 6321

Query: 1151 DLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQHPHS 1210
               +   K+  +  S  LY+ +L    G A   P T E+E  K+  E  S   Y+++   
Sbjct: 6322 TPEMQRVKRNQENISSVLYKENL----GKATPTPFTPEMERVKRNQENFSSVLYKENMR- 6376

Query: 1211 FKYTAVTDTPNLLHAKFSNQITNERLYK-AAGEDARHEYTMTLGLPEFIRAKTNAANLSD 1269
             K T    TP +  AK + +  +  LY  +  +  + +    L  PE  R +    ++S 
Sbjct: 6377 -KATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMRRVRETQRHIST 6435

Query: 1270 ARYKESW 1276
             +Y E +
Sbjct: 6436 VKYHEDF 6442



 Score = 82.8 bits (203), Expect = 3e-15
 Identities = 114/487 (23%), Positives = 199/487 (40%), Gaps = 51/487 (10%)

Query: 70   TPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANERAYWTGYGE 129
            TP  +  R   +  S I  ++  E  K+ F   + + +   A   + L++++ Y     +
Sbjct: 6031 TPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEK 6090

Query: 130  GNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLA 188
              ++    L  PEI R+ E +K+    +Y  D +  +GK +     TP   R K+  +  
Sbjct: 6091 SMSYYETVLDTPEIQRVRENQKNFSLLQYQCDLKNSKGKITV-VQDTPEILRVKENQKNF 6149

Query: 189  SQVEYKRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248
            S V YK    E +S  + +  TPE++R K      S V+Y E      G+G+ P    P 
Sbjct: 6150 SSVLYK----EDVSPGTAIGKTPEMMRVKQTQDHISSVKYKEAI----GQGT-PIPDLPE 6200

Query: 249  YQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYPEE-YEEHRG 307
             +  K   +  S V Y     KE  G   P      I   E   +  + +    Y+E+ G
Sbjct: 6201 VKRVKETQKHISSVMY-----KENLGTGIPTTVTPEI---ERVKRNQENFSSVLYKENLG 6252

Query: 308  KGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKL 367
            KG  P  ITP  +  K+  E  S + Y+++  K          P      +++ +   + 
Sbjct: 6253 KG-IPTPITPEMERVKRNQENFSSVLYKENMGK--------GTPLAVTPEMERVKHNQEN 6303

Query: 368  VSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDR 427
            +S V YK+++  +    +    TP+ + V +  +  S   YKEN      G+        
Sbjct: 6304 ISSVLYKENVGKATATPV----TPEMQRVKRNQENISSVLYKENL-----GKATPTPFTP 6354

Query: 428  RTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTPSYQTAMK------LVPLKDANYRQ 481
                  +     S+V YK + +        P  +TP  + A +       V   D+  +Q
Sbjct: 6355 EMERVKRNQENFSSVLYKENMRKAT-----PTPVTPEMERAKRNQENISSVLYSDSFRKQ 6409

Query: 482  SIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKL 541
               K  Y  V DTP++ + +   + +S V Y  D+EK+K  +T     P   + K N + 
Sbjct: 6410 IQGKAAY--VLDTPEMRRVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQD 6467

Query: 542  FSEVKYK 548
            FS++ Y+
Sbjct: 6468 FSDINYR 6474


>gi|169217576 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 410

 Score =  330 bits (846), Expect = 7e-90
 Identities = 167/395 (42%), Positives = 250/395 (63%)

Query: 772  LQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRG 831
            LQA  NA  +S KLY+  W + K KG+++R D++    AKA R++ASE KYKE Y +  G
Sbjct: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 832  KLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLAT 891
              +G + +Q D +   ++  +K+QS+ EYKK +E +K   +  LDM+ +V A+K Q L +
Sbjct: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121

Query: 892  DVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKK 951
            D+ Y+   H +T LP    V  AKKAY LQSDN Y++D++W+KG+GW+  GS+ V + K 
Sbjct: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181

Query: 952  AGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHHYTPTADL 1011
            A  L++E+ YR  P+ALKFTSI DTPE++QA+I+  Q  + LYR   E  K +    AD 
Sbjct: 182  AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241

Query: 1012 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1071
            P +L +K+NA+ IS  RY+++W  ++  GY LR DA+  Q AKAS +I SDY YK A+EK
Sbjct: 242  PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301

Query: 1072 MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQT 1131
             KG  +G RS ++D  L  +     +Q+D  YKK +   KA+  +P+DM ++  AK+ Q 
Sbjct: 302  QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361

Query: 1132 LASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSE 1166
            LAS+ DY+H L  ++   +   +  A+KA+ LQS+
Sbjct: 362  LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  300 bits (767), Expect = 1e-80
 Identities = 157/396 (39%), Positives = 241/396 (60%), Gaps = 4/396 (1%)

Query: 532 LVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591
           +++A  NA   S   Y++ W  TK KG++++ DA+ +  AKAS E+AS  KYKE Y K  
Sbjct: 1   MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 592 GKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLA 647
           G  MG      D + + ++  AK+ S+ EYKK +E+SK   + P+DM++I  AKK Q L 
Sbjct: 61  GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 648 SDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAK 707
           SD+DYR  LH++T LP+      AKKAY LQS+  YK+DL W+KG+GWL EGS+ + + K
Sbjct: 121 SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 708 KAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 767
            A  L++E+ YR + + LKFTS+ D+ ++  AK +    S   Y+   E+      +  D
Sbjct: 181 NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 768 EPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYE 827
            PL LQ++ NA  +S K Y+ +WE+ K  G++LR D++    AKA RD+AS+  YK  YE
Sbjct: 241 TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 828 RSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQ 887
           + +G  IG +  + D ++  +  + K+Q++  YKK + D K++  + +DMV +  A++ Q
Sbjct: 301 KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 888 HLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSD 923
            LA+DV Y+   HH++  P    V  A+KAY LQSD
Sbjct: 361 ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSD 396



 Score =  298 bits (764), Expect = 2e-80
 Identities = 150/397 (37%), Positives = 247/397 (62%)

Query: 1014 VLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEKMK 1073
            +L A +NA+ IS   Y++ W+  +  GY +R DA+  + AKAS EI S+YKYKE + K  
Sbjct: 1    MLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL 60

Query: 1074 GQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAALVHAKKAQTLA 1133
            G  +G R+L+DD     +++A  +QSD  YKK +E SK   + PLDM ++V AKK Q L 
Sbjct: 61   GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV 120

Query: 1134 SNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRK 1193
            S+ DY++ L Q+T L +   +  AKKA+ LQS+NLY+SDL +++G+  +  G++E+   K
Sbjct: 121  SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK 180

Query: 1194 KASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHEYTMTLG 1253
             A  L++E  YR  P + K+T++ DTP ++ AK +    +E LY+ A E  +    +   
Sbjct: 181  NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPAD 240

Query: 1254 LPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFV 1313
             P  +++K NA  +S+ RY+++W +++  GY L  +A+  Q A+AS DIASD+LY+  + 
Sbjct: 241  TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE 300

Query: 1314 KERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQ 1373
            K++G  IG +S ++DP++     + ++Q++  Y++     +A+  +P+DMV +  AK  Q
Sbjct: 301  KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ 360

Query: 1374 ALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSEL 1410
            ALASD DYR   H ++  P+   +  A+KA+ LQS++
Sbjct: 361  ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397



 Score =  283 bits (724), Expect = 1e-75
 Identities = 146/396 (36%), Positives = 241/396 (60%)

Query: 1258 IRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASDFLYRHDFVKERG 1317
            ++A  NA  +S+  Y++ W + + +GY +  +A+  + A+AS +IAS++ Y+  + K+ G
Sbjct: 2    LQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLG 61

Query: 1318 KLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALAS 1377
              +G ++++DDP+        ++QS+ +Y++    S+   + P+DM+ +V AK  Q L S
Sbjct: 62   HHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVS 121

Query: 1378 DHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKK 1437
            D DYR   H++T LP+   +  AKKA+ LQS+  YKSDL  +KGIGWL   S ++   K 
Sbjct: 122  DIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKN 181

Query: 1438 AGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDH 1497
            A  L++E  YR KP+++KFT++VD+P+++ AK + +  +E +YR+   +      +  D 
Sbjct: 182  AQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADT 241

Query: 1498 PDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLR 1557
            P   ++++NAL +S+K Y+ +WE  +   YD R DAI  Q A+ASR+IASD+ YK A+ +
Sbjct: 242  PLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEK 301

Query: 1558 DRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQ 1617
             +G  IG RS  +DP++    NV ++Q+D  YKK +   +++     D   +  AK  Q 
Sbjct: 302  QKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQA 361

Query: 1618 LASDVHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDV 1653
            LASDV YR  L   +C P+Q  +  A+KA+ LQSDV
Sbjct: 362  LASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397



 Score =  191 bits (486), Expect = 4e-48
 Identities = 125/390 (32%), Positives = 202/390 (51%), Gaps = 14/390 (3%)

Query: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLV 357
           Y +++ + + KG          ++AK + E+AS+ KY++ + K  G  H      QD+  
Sbjct: 16  YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH-HMGFRTLQDDPK 74

Query: 358 LKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKENYQNHMR 417
              A    K+ S+ EYKK  E S+G      +        K     SD  Y+ NY +   
Sbjct: 75  SVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-NYLH--- 130

Query: 418 GRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--HDIVDYNYPATLTPSYQTAMKLVPLK 475
            ++  +      + A K   L S+  YK+D +    I      +      + A  L  L 
Sbjct: 131 -QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNL--LN 187

Query: 476 DANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKA 535
           +  YR   + LK++S+ DTP+++QAKINA Q+S   YR  +EK K N  +P D P ++++
Sbjct: 188 ERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQS 247

Query: 536 KTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAM 595
           K NA   S  +Y++ WE  K  G++++ DA+ +  AKAS ++AS+  YK  YEK KG  +
Sbjct: 248 KINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYI 307

Query: 596 G----TADSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLD 651
           G      D +L+ +  + KM ++  YKK + + K +  +P+DMV+I  AK+ Q LASD+D
Sbjct: 308 GCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQALASDVD 367

Query: 652 YRKKLHEYTVLPEDMKTQWAKKAYGLQSEL 681
           YR  LH ++  P+      A+KAY LQS++
Sbjct: 368 YRHYLHHWSCFPDQNDVIQARKAYDLQSDV 397



 Score =  165 bits (418), Expect = 3e-40
 Identities = 80/187 (42%), Positives = 119/187 (63%)

Query: 1502 RARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGL 1561
            +A +NAL +S+K+Y+  W  T+   YD R DAI  + A+ASREIAS+++YKE + +  G 
Sbjct: 3    QAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGH 62

Query: 1562 QIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASD 1621
             +G+R++ DDP+    ++  ++QSD EYKK + KS+   ++  D   ++QAK+ Q L SD
Sbjct: 63   HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSD 122

Query: 1622 VHYRQPLPQPTCDPEQLGLRHAQKAHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRA 1681
            + YR  L Q TC P+Q  +  A+KA+ LQSD  YKSDL   +G+GW P GS +V   + A
Sbjct: 123  IDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNA 182

Query: 1682 AELANAR 1688
              L N R
Sbjct: 183  QNLLNER 189



 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 94/437 (21%), Positives = 183/437 (41%), Gaps = 92/437 (21%)

Query: 157 YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDERISR---FSTVVDTPEL 213
           Y +D+   + KG          + AK + ++AS+ +YK G+ +++     F T+ D P+ 
Sbjct: 16  YQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTLQDDPKS 75

Query: 214 LRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMR 273
           + +   A++QSD  Y + YE+ +G  + P  +    Q AK+   L SD+ Y + Y  +  
Sbjct: 76  VWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVLVSDIDY-RNYLHQWT 133

Query: 274 GMAGPAIGAEGILTRECADQYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333
            +                       P++ +                  AKKA++L SD  
Sbjct: 134 CL-----------------------PDQND---------------VIQAKKAYDLQSDNL 155

Query: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQF 393
           Y+ D   +KG      LP + ++ + + ++   L++E  Y+   E+ +  SI   +TP+ 
Sbjct: 156 YKSDLEWLKGIGW---LP-EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSI--VDTPE- 208

Query: 394 RNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV 453
                                          + +  ++A+++    S   Y+  ++ +  
Sbjct: 209 -------------------------------VIQAKINAVQI----SEPLYRNAWEKEKA 233

Query: 454 DYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLK---YSSVTDTPQIVQAKINAQQLSHV 510
           + N PA      Q+ +  + + +  Y+Q+ + +K   Y    D   I  AK +    S  
Sbjct: 234 NVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDY 293

Query: 511 NYRADYEKNKLNY---TLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMS 567
            Y+  YEK K +Y      ++ P+LV A    K+ ++  YK+ +   K K   + +D +S
Sbjct: 294 LYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAK-ISIPVDMVS 352

Query: 568 LLAAKASGELASNIKYK 584
           + AAK    LAS++ Y+
Sbjct: 353 ISAAKEGQALASDVDYR 369



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 72/339 (21%), Positives = 133/339 (39%), Gaps = 57/339 (16%)

Query: 1339 QLQSELQYRRGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK-------FTAL 1391
            Q+ ++L  +    + Q  + +  D + + HAK ++ +AS++ Y+  Y K       F  L
Sbjct: 10   QISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQLGHHMGFRTL 69

Query: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKP 1451
             +D K  WA  A  +QS+  YK      KGI    L    +  AKK   L+S+  YR   
Sbjct: 70   QDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNY- 128

Query: 1452 DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLS 1511
                                                LH++T +PD  D  +A+      S
Sbjct: 129  ------------------------------------LHQWTCLPDQNDVIQAKKAYDLQS 152

Query: 1512 DKVYRNSWEQTRAGSYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDD 1571
            D +Y++  E  +   +      +P  +    R   +     E   R +   + + S+ D 
Sbjct: 153  DNLYKSDLEWLKGIGW------LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDT 206

Query: 1572 PRMKHFLNVGRLQ-SDNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQ 1630
            P +     +  +Q S+  Y+  + K ++  +   D P +LQ+K +    S+  Y+Q    
Sbjct: 207  PEVIQ-AKINAVQISEPLYRNAWEKEKANVNVPADTPLMLQSKINALQISNKRYQQAWED 265

Query: 1631 PTCD-----PEQLGLRHAQKAHQLQSDVKYKSDLNLTRG 1664
                      + +G++HA+ +  + SD  YK+     +G
Sbjct: 266  VKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKG 304



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 67/278 (24%), Positives = 113/278 (40%), Gaps = 59/278 (21%)

Query: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193
           LPD   V  ++A+K+   +    Y  D E  +G G  P        R K A  L ++  Y
Sbjct: 135 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 191

Query: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITP------ 247
           +   +    +F+++VDTPE++++K  A   S+  Y   +E+++   + PA  TP      
Sbjct: 192 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKANVNVPA-DTPLMLQSK 248

Query: 248 ------------------------------AYQIAKRANELASDVRYHQQYQKEMRGMAG 277
                                           Q AK + ++ASD  Y   Y+K+     G
Sbjct: 249 INALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYEKQKGHYIG 308

Query: 278 PAIGAEGILTRECAD----QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIK 333
                E       A+    Q  + Y + Y +H+ K S P  +  +   AK+   LASD+ 
Sbjct: 309 CRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMV-SISAAKEGQALASDVD 367

Query: 334 YRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEV 371
           YR   +      H+   P Q++++  QA+    L S+V
Sbjct: 368 YRHYLH------HWSCFPDQNDVI--QARKAYDLQSDV 397


>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
          Length = 1014

 Score =  194 bits (493), Expect = 6e-49
 Identities = 198/822 (24%), Positives = 376/822 (45%), Gaps = 57/822 (6%)

Query: 484  DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFS 543
            D++ Y  V +   +  A+   + +S + Y+ +++K+K   T   D P L   K      S
Sbjct: 26   DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85

Query: 544  EVKYKEGWEKTKGKGFEMKLDAM--SLLAAKASGELASNIKYKEEYEKTKG---KAMGTA 598
            E KYK   +         ++ A   S+ A + + +L S + YK++++  KG    A    
Sbjct: 86   EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVT-QLQSEVAYKQKHDAAKGFSDYAHMKE 144

Query: 599  DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKK--- 655
               + H++++ K  S + Y+K  +++ T +   +D  +I+ A +   + S+ +Y+K    
Sbjct: 145  PPEVKHAMEVNKHQSNISYRKDVQDTHT-YSAELDRPDIKMATQISKIISNAEYKKGQGI 203

Query: 656  LHEYTVLPEDMKTQWAKKAYGLQSELQYKADL---AWMKGVGWLTEGSLNLEQAKKAGQL 712
            +++   +      + A +A  L S+++YK         K   +    S +  Q + A  L
Sbjct: 204  MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATL 263

Query: 713  VSEKNYRQRVDELK--FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPL 770
             S   Y++ +  +    + + +   ++H  K+ ++ SG  YK   E++   Y    D   
Sbjct: 264  ASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVE 323

Query: 771  FLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERS- 829
             L  + NA   S+  YK  +E  K K     +++ ++ A+K  + + SE  YKED+E+  
Sbjct: 324  HLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEI 383

Query: 830  RGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFED--TKSQCHVSLDMVHLVHARKAQ 887
            +G+   + D+    +  H   ++ L  E EYKK  E+        ++ +++ +  A++A 
Sbjct: 384  KGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRAS 441

Query: 888  HLATDVGYK------TAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKW-MKGMGW-V 939
             +A++  YK             A    ++++ AKKA  + S+  Y+ D++  +KG G  V
Sbjct: 442  EMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQV 501

Query: 940  ATGSLNVEQAKKAGELISEKKYRQH-PDALKFTSIK---DTPEMVQARISYTQAVDRLYR 995
            +T +L+V++AKKA E+ S+K+Y++   + +K   ++   D P++++A+ +      R Y+
Sbjct: 502  STDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYK 561

Query: 996  EQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKA 1055
            ++ E +  +Y+  AD PE+   K    NIS   YK+       G      D+   +  K 
Sbjct: 562  DEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKK-----EVGAGTAVKDSPEIERVKK 616

Query: 1056 SGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFH 1115
            + + IS  KYKE       ++  + ++ D   L          S++ YK+  ++ KA   
Sbjct: 617  NQQNISSVKYKE-------EIKHATAISDPPELKRVKENQKNISNLQYKE--QNYKA--- 664

Query: 1116 LPLDMA-ALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLN 1174
             P+ M   +   ++ Q   S   YK  L + T++++   L  AK+  K  S   YR  L 
Sbjct: 665  TPVSMTPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL- 723

Query: 1175 FMRGVACVIPGTLEIEGRKKASELISESKYRQHPHSFK--YTAVTDTPNLLHAK-FSNQI 1231
               G A  +  T E+E  KK  E IS  KY Q     K   + + DTP + H K   N I
Sbjct: 724  ---GRATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHI 780

Query: 1232 TNERLYKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYK 1273
            +  + ++   +     +T  +  P   R + N   +SDA YK
Sbjct: 781  SMVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  191 bits (484), Expect = 7e-48
 Identities = 216/826 (26%), Positives = 357/826 (43%), Gaps = 97/826 (11%)

Query: 351  PAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQFRNVSKISKFTSDNKYKE 410
            P  ++L ++ A+   +L+S++ YK++ + S+       ++P   +V  I  F S+ KYK 
Sbjct: 32   PVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKG 91

Query: 411  NYQNHM-RGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV----DYNYPATLTPSY 465
              +  +    Y+ +     ++ A +V  L S VAYK   KHD      DY +     P  
Sbjct: 92   TIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYK--QKHDAAKGFSDYAHMKE-PPEV 148

Query: 466  QTAMKL-VPLKDANYRQSI-DKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLNY 523
            + AM++     + +YR+ + D   YS+  D P I      A Q+S +   A+Y+K +   
Sbjct: 149  KHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKM----ATQISKIISNAEYKKGQGIM 204

Query: 524  TLPQDV---PQLVKAKTNAKLFSEVKYKEGW--EKTKGKGFEMKLDAMSLLAAKASGELA 578
                 V   P    A   +KL S++KYKE +  E    K     L++ S    + +  LA
Sbjct: 205  NKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLA 264

Query: 579  SNIKYKEEYEKTKGKAMGTADSRLL-HSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 637
            SN+KYK++ +          +   L H L+ +KM S  EYKK FEE+K  +H   D V  
Sbjct: 265  SNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEH 324

Query: 638  RHAKKAQTLASDLDYRKKLHEYTVLP-----EDMKTQWAKKAYGLQSELQYKADLA---- 688
             H K    L S + Y+++  +    P     E    Q +K+A  +QSE  YK D      
Sbjct: 325  LHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIK 384

Query: 689  ----------------------------------WMKGVGW-LTEGSLNLEQAKKAGQLV 713
                                               +KG G  L    L++++AK+A ++ 
Sbjct: 385  GRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMA 444

Query: 714  SEKNYRQRVDEL----KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV--HQYTISKD 767
            SEK Y++ ++ +       + TD+ +M+HAKK+ E+ S   YK   E  +      +S D
Sbjct: 445  SEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTD 504

Query: 768  EPLFLQARANAANLSEKLYKSSWENQ-KAKGFELRLDSLTFLAAKAKRDLASEVKYKEDY 826
                 +A+  +   S+K YK   EN+ K KG ++ +D    L AK   ++ S+ KYK++ 
Sbjct: 505  TLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEA 564

Query: 827  ERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKA 886
            E+         D     ++  + Q     S + YKK   +  +   V  D   +   +K 
Sbjct: 565  EKMLSNYSTIADTPEIQRIKTTQQNI---SAVFYKK---EVGAGTAVK-DSPEIERVKKN 617

Query: 887  QHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATG---S 943
            Q   + V YK    H TA+    +++  K+     S+ QY       K   + AT    +
Sbjct: 618  QQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQY-------KEQNYKATPVSMT 670

Query: 944  LNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKH 1003
              +E+ ++  E +S  KY+   +  + T+I D PE+ +A+ +     +  YR Q      
Sbjct: 671  PEIERVRRNQEQLSAVKYK--GELQRGTAISDPPELKRAKENQKNISNVYYRGQ----LG 724

Query: 1004 HYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDY 1063
              T  +  PE+   K N  NIS  +Y +   +++ G   L LD    +  K +   IS  
Sbjct: 725  RATTLSVTPEMERVKKNQENISSVKYTQDHKQMK-GRPSLILDTPAMRHVKEAQNHISMV 783

Query: 1064 KYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1109
            KY E FEK KG+  G   + DD         T + SD  YK    H
Sbjct: 784  KYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 827



 Score =  179 bits (453), Expect = 3e-44
 Identities = 205/804 (25%), Positives = 351/804 (43%), Gaps = 118/804 (14%)

Query: 322  AKKAHELASDIKYRQDFNKMK------------------GA-----------------AH 346
            A+K  EL SDI+Y+++F K K                  GA                 + 
Sbjct: 42   ARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSL 101

Query: 347  YHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHS--INYCETPQFRNVSKISKFTS 404
            Y  +PA  + V   A  V +L SEV YK+  ++++G S   +  E P+ ++  +++K  S
Sbjct: 102  YKRMPATIDSVF--AGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQS 159

Query: 405  DNKYKENYQNH----------------------MRGRY-EGVGMDRRT---------LHA 432
            +  Y+++ Q+                           Y +G G+  +           HA
Sbjct: 160  NISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYKKGQGIMNKEPAVIGRPDFEHA 219

Query: 433  MKVGSLASNVAYKADYKHDIVD--YNYPATLTPSY-QTAMKLVPLKDANYRQSIDKLKYS 489
            ++   L+S + YK  + +++ D  ++Y    + S+ Q  +      +  Y++ I  + + 
Sbjct: 220  VEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLASNVKYKKDIQNM-HD 278

Query: 490  SVTDTPQIV---QAKINAQQLSHVNYRADYEKNKLNYTLPQDVPQLVKAKTNAKLFSEVK 546
             V+D P ++        ++ LS   Y+  +E+NK  Y    D  + +  K NA L S+VK
Sbjct: 279  PVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHLHHKGNAVLQSQVK 338

Query: 547  YKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEK-TKGKAMGTADS--RLL 603
            YKE +EK KGK     ++  S  A+K + ++ S   YKE++EK  KG++    D     L
Sbjct: 339  YKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFL 398

Query: 604  HSLQIAKMSSEVEYKKGFE-ESKTR-FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE--- 658
            H   I  +  E EYKK  E E K +   L  ++++I+ AK+A  +AS+ +Y+K L     
Sbjct: 399  HVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASEMASEKEYKKDLESIIK 458

Query: 659  ---YTVLPEDMKTQWAKKAYGLQSELQYKADL-AWMKGVGW-LTEGSLNLEQAKKAGQLV 713
                    + ++ Q AKKA  + SE  YK DL   +KG G  ++  +L++++AKKA ++ 
Sbjct: 459  GKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMA 518

Query: 714  SEKNYRQRVD-ELKFTSV---TDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEP 769
            S+K Y++ ++ E+K   +    D   +  AK++ E+ S   YK   E+ +  Y+   D P
Sbjct: 519  SQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTP 578

Query: 770  LFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYKEDYERS 829
               + +    N+S   YK     +   G  ++ DS      K  +   S VKYKE+ +  
Sbjct: 579  EIQRIKTTQQNISAVFYK----KEVGAGTAVK-DSPEIERVKKNQQNISSVKYKEEIKH- 632

Query: 830  RGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHL 889
                  A  +    ++    +  K  S L+YK   E       VS+    +   R+ Q  
Sbjct: 633  ------ATAISDPPELKRVKENQKNISNLQYK---EQNYKATPVSM-TPEIERVRRNQEQ 682

Query: 890  ATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQA 949
             + V YK      TA+    +++ AK+     S+  YR  +    G     + +  +E+ 
Sbjct: 683  LSAVKYKGELQRGTAISDPPELKRAKENQKNISNVYYRGQL----GRATTLSVTPEMERV 738

Query: 950  KKAGELISEKKYRQHPDALKF--TSIKDTPEMVQARISYTQAVDRLYREQGENIK-HHYT 1006
            KK  E IS  KY Q    +K   + I DTP M   + +        Y E  E  K   +T
Sbjct: 739  KKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFT 798

Query: 1007 PTADLPEVLLAKLNAMNISETRYK 1030
            P  D P     + N   +S+  YK
Sbjct: 799  PVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  176 bits (447), Expect = 1e-43
 Identities = 204/817 (24%), Positives = 349/817 (42%), Gaps = 78/817 (9%)

Query: 723  DELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLS 782
            D++ +  V +   ME A+K  EL S + YK   ++S  + T   D P+    +   A +S
Sbjct: 26   DQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFIS 85

Query: 783  EKLYKSSWENQKAKGFELRLDS-LTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQG 841
            E  YK + +   +     R+ + +  + A     L SEV YK+ ++ ++G       ++ 
Sbjct: 86   EAKYKGTIKADLSNSLYKRMPATIDSVFAGEVTQLQSEVAYKQKHDAAKG-FSDYAHMKE 144

Query: 842  DSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGYKTAEHH 901
              ++ H+++++K QS + Y+K  +DT +     LD   +  A +   + ++  YK  +  
Sbjct: 145  PPEVKHAMEVNKHQSNISYRKDVQDTHTYS-AELDRPDIKMATQISKIISNAEYKKGQGI 203

Query: 902  FTALPT-------DMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGE 954
                P        +  VE +K +  ++   ++  ++K  K   +    S +  Q + A  
Sbjct: 204  MNKEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHH-YNPLESASFRQNQLAAT 262

Query: 955  LISEKKYRQHPDALKFTSIKDTPEMV---QARISYTQAVDRLYREQGENIKHHYTPTADL 1011
            L S  KY++    +    + D P ++       +      R Y++  E  K  Y   AD 
Sbjct: 263  LASNVKYKKDIQNMH-DPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADA 321

Query: 1012 PEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIISDYKYKEAFEK 1071
             E L  K NA+  S+ +YKE + K +       ++   +QA+K + ++ S+  YKE FEK
Sbjct: 322  VEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYKEDFEK 381

Query: 1072 -MKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMAAL--VHAKK 1128
             +KG+   S  L+      H  Y T+L  +  YKK  E+      + L+   L    AK+
Sbjct: 382  EIKGR--SSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKR 439

Query: 1129 AQTLASNQDYKHPLPQYT------SLAEDLRLSCAKKAHKLQSENLYRSDLNF-MRGVAC 1181
            A  +AS ++YK  L          +  + L +  AKKA ++ SE  Y+ DL   ++G   
Sbjct: 440  ASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGM 499

Query: 1182 -VIPGTLEIEGRKKASELISESKYRQH-PHSFKYTAVT---DTPNLLHAKFSNQITNERL 1236
             V   TL+++  KKASE+ S+ +Y++   +  K   +    D P++L AK +++I ++R 
Sbjct: 500  QVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAKRTSEIYSQRK 559

Query: 1237 YKAAGEDARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALP-FQA 1295
            YK   E     Y+     PE  R KT   N+S   YK+        G    ++  P  + 
Sbjct: 560  YKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKE------VGAGTAVKDSPEIER 613

Query: 1296 ARASGDIASDFLYRHDF--------------VKERGKLIGPQSVRDD----------PRI 1331
             + +    S   Y+ +               VKE  K I     ++           P I
Sbjct: 614  VKKNQQNISSVKYKEEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTPEI 673

Query: 1332 QHCRRMGQLQSELQYR----RGATSSQAQFHLPMDMVHLVHAKNAQALASDHDYRTQYHK 1387
            +  RR  +  S ++Y+    RG   S        D   L  AK  Q   S+  YR Q  +
Sbjct: 674  ERVRRNQEQLSAVKYKGELQRGTAIS--------DPPELKRAKENQKNISNVYYRGQLGR 725

Query: 1388 FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKY 1447
             T L    +M   KK     S ++Y  D   MKG   L L +P M   K+A   IS  KY
Sbjct: 726  ATTLSVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKY 785

Query: 1448 RKKPDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1481
             +  +  K   FT VVD P     + +    ++  Y+
Sbjct: 786  HEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 822



 Score =  168 bits (425), Expect = 5e-41
 Identities = 215/898 (23%), Positives = 380/898 (42%), Gaps = 116/898 (12%)

Query: 138 LPDPEIVRMVEARKSLGEEYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGH 197
           +P  E ++     + +GEE  E+ +Q   K   P +   + + A+K  +L S + YK   
Sbjct: 3   VPVFEDIKDETEEEKIGEEENEE-DQVFYK---PVIEDLSMELARKCTELISDIRYKEEF 58

Query: 198 DERISRFSTVVDTPELLRSK-----------------------------------AG--A 220
            +   + + V D+P L   K                                   AG   
Sbjct: 59  KKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKADLSNSLYKRMPATIDSVFAGEVT 118

Query: 221 QLQSDVRYTEDYEQQRGKGSFPAM-ITPAYQIAKRANELASDVRYHQQYQKEMRGMA--- 276
           QLQS+V Y + ++  +G   +  M   P  + A   N+  S++ Y +  Q      A   
Sbjct: 119 QLQSEVAYKQKHDAAKGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELD 178

Query: 277 GPAIGAEGILTRECADQYGQGYPEEYEEHRG-KGSFPAMI-TPAYQNAKKAHELASDIKY 334
            P I     +++  ++        EY++ +G     PA+I  P +++A +A +L+S IKY
Sbjct: 179 RPDIKMATQISKIISN-------AEYKKGQGIMNKEPAVIGRPDFEHAVEASKLSSQIKY 231

Query: 335 RQDF-NKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQF 393
           ++ F N+MK   H+++    ++   +Q Q    L S V+YKKD+++      +       
Sbjct: 232 KEKFDNEMKDKKHHYN--PLESASFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFL 289

Query: 394 RNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKHDIV 453
            +V K SK  S  +YK+ ++ + +G Y         LH      L S V YK +Y+ +  
Sbjct: 290 DHVLKASKMLSGREYKKLFEEN-KGMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKG 348

Query: 454 DYNYPATLTPSYQTAMKLVPLKDAN-YRQSIDK-LKYSSVTD---TPQIVQAKINAQQLS 508
                   TPSYQ + +   ++    Y++  +K +K  S  D   TP+ +  K     L 
Sbjct: 349 KPMLEFVETPSYQASKEAQKMQSEKVYKEDFEKEIKGRSSLDLDKTPEFLHVKYITNLLR 408

Query: 509 HVNYRADYE---KNKLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEK-TKGKGFEMKLD 564
              Y+ D E   K K    L  +V  + +AK  +++ SE +YK+  E   KGKG +   D
Sbjct: 409 EKEYKKDLENEIKGK-GMELNSEVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTD 467

Query: 565 AMSLLAAKASGELASNIKYKEEYE---KTKGKAMGTADSRLLHSLQIAKMSSEVEYKKGF 621
            + +  AK + E+AS   YK + E   K KG  + T    +  + + ++M+S+ +YKK  
Sbjct: 468 TLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDL 527

Query: 622 E-ESKTR-FHLPMDMVNIRHAKKAQTLASDLDYR----KKLHEYTVLPEDMKTQWAKKAY 675
           E E K +   + MD+ +I  AK+   + S   Y+    K L  Y+ + +  + Q  K   
Sbjct: 528 ENEIKGKGMQVSMDIPDILRAKRTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQ 587

Query: 676 GLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQ 735
              S + YK ++    G G   + S  +E+ KK  Q +S   Y++ +     T+++D  +
Sbjct: 588 QNISAVFYKKEV----GAGTAVKDSPEIERVKKNQQNISSVKYKEEIKHA--TAISDPPE 641

Query: 736 MEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKLYKSSWENQKA 795
           ++  K++Q+  S + YK  N    ++ T     P   + R N   LS   YK   +   A
Sbjct: 642 LKRVKENQKNISNLQYKEQN----YKATPVSMTPEIERVRRNQEQLSAVKYKGELQRGTA 697

Query: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855
                  D      AK  +   S V Y       RG+L  A  +    +M    +  +  
Sbjct: 698 IS-----DPPELKRAKENQKNISNVYY-------RGQLGRATTLSVTPEMERVKKNQENI 745

Query: 856 SELEYKKGFEDTKSQCHVSLDMVHLVHARKAQHLATDVGY-----KTAEHHFTALPTDMK 910
           S ++Y +  +  K +  + LD   + H ++AQ+  + V Y     KT    FT +  D  
Sbjct: 746 SSVKYTQDHKQMKGRPSLILDTPAMRHVKEAQNHISMVKYHEDFEKTKGRGFTPVVDDPV 805

Query: 911 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDAL 968
            E  +K   + SD  Y+     +            VE  ++ G ++  K +R  P ++
Sbjct: 806 TERVRKNTQVVSDAAYKGVHPHI------------VEMDRRPGIIVDLKVWRTDPGSI 851



 Score =  160 bits (406), Expect = 8e-39
 Identities = 195/804 (24%), Positives = 338/804 (42%), Gaps = 82/804 (10%)

Query: 908  DMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELISEKKYRQHPDA 967
            D+ +E A+K   L SD +Y+ + K  K      T S  +   K  G  ISE KY+    A
Sbjct: 36   DLSMELARKCTELISDIRYKEEFKKSKDKCTFVTDSPMLNHVKNIGAFISEAKYKGTIKA 95

Query: 968  -LKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-------YTPTADLPEVLLAKL 1019
             L  +  K  P  + +   +   V +L  E     KH        Y    + PEV     
Sbjct: 96   DLSNSLYKRMPATIDS--VFAGEVTQLQSEVAYKQKHDAAKGFSDYAHMKEPPEVK---- 149

Query: 1020 NAMNISETRYKESWSK-LRDGG-YKLRLDALPFQAAKASGEIISDYKYKEAFEKMKGQML 1077
            +AM +++ +   S+ K ++D   Y   LD    + A    +IIS+ +YK    K +G M 
Sbjct: 150  HAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIISNAEYK----KGQGIMN 205

Query: 1078 GSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS---KAQFHLPLDMAALVHAKKAQTLAS 1134
               ++       H+V A+ L S + YK+ F++    K   + PL+ A+    + A TLAS
Sbjct: 206  KEPAVIGRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESASFRQNQLAATLAS 265

Query: 1135 NQDYKHPLPQYTSLAEDLR----LSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIE 1190
            N  YK  +        DL     L    KA K+ S   Y+      +G+       +E  
Sbjct: 266  NVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENKGMYHFDADAVEHL 325

Query: 1191 GRKKASELISESKYRQHPHSFKYTAV---TDTPNLLHAKFSNQITNERLYKAAGEDARHE 1247
              K  + L S+ KY++     K   +    +TP+   +K + ++ +E++YK   ED   E
Sbjct: 326  HHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSEKVYK---EDFEKE 382

Query: 1248 YTMTLGL-----PEFIRAKTNAANLSDARYKESWRN-LRAQGYKLTIEALPFQAARASGD 1301
                  L     PEF+  K     L +  YK+   N ++ +G +L  E L  Q A+ + +
Sbjct: 383  IKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNSEVLDIQRAKRASE 442

Query: 1302 IASDFLYRHDFVKE-RGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSS--QAQFH 1358
            +AS+  Y+ D     +GK  G Q+  D   +QH ++  ++ SE  Y+R   +        
Sbjct: 443  MASEKEYKKDLESIIKGK--GMQAGTDTLEMQHAKKAAEIASEKDYKRDLETEIKGKGMQ 500

Query: 1359 LPMDMVHLVHAKNAQALASDHDYRTQYHKFTA---------LPEDLKMAWAKKAHALQSE 1409
            +  D + +  AK A  +AS   Y+                 +P+ L+   AK+   + S+
Sbjct: 501  VSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILR---AKRTSEIYSQ 557

Query: 1410 LRYKSDLIGMKGIGWLALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAK 1469
             +YK +   M         +P+++  K   + IS   Y+K+  +   T V DSP++   K
Sbjct: 558  RKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKKEVGA--GTAVKDSPEIERVK 615

Query: 1470 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1529
             +  + +   Y+    E +   T I D P+  R + N  ++S+  Y+    +    S   
Sbjct: 616  KNQQNISSVKYK----EEIKHATAISDPPELKRVKENQKNISNLQYKEQNYKATPVSMTP 671

Query: 1530 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589
             ++ +     R ++E  S  +YK    R         ++ D P +K      +  S+  Y
Sbjct: 672  EIERV-----RRNQEQLSAVKYKGELQRGT-------AISDPPELKRAKENQKNISNVYY 719

Query: 1590 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQL----GLRHAQK 1645
            +    ++ +     +  P + + K++Q+  S V Y Q   Q    P  +     +RH ++
Sbjct: 720  RGQLGRATTL----SVTPEMERVKKNQENISSVKYTQDHKQMKGRPSLILDTPAMRHVKE 775

Query: 1646 AHQLQSDVKYKSDLNLTRGVGWTP 1669
            A    S VKY  D   T+G G+TP
Sbjct: 776  AQNHISMVKYHEDFEKTKGRGFTP 799



 Score =  142 bits (358), Expect = 3e-33
 Identities = 170/740 (22%), Positives = 310/740 (41%), Gaps = 83/740 (11%)

Query: 991  DRLYREQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPF 1050
            +++  E+ E  +  Y P  +   + LA+     IS+ RYKE + K +D       D+   
Sbjct: 16   EKIGEEENEEDQVFYKPVIEDLSMELARKCTELISDIRYKEEFKKSKDK-CTFVTDSPML 74

Query: 1051 QAAKASGEIISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHS 1110
               K  G  IS+ KYK   +      L  R +   I    +   T LQS+V YK+  + +
Sbjct: 75   NHVKNIGAFISEAKYKGTIKADLSNSLYKR-MPATIDSVFAGEVTQLQSEVAYKQKHDAA 133

Query: 1111 K--AQFHLPLDMAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLR---LSCAKKAHKLQS 1165
            K  + +    +   + HA +     SN  Y+  +    + + +L    +  A +  K+ S
Sbjct: 134  KGFSDYAHMKEPPEVKHAMEVNKHQSNISYRKDVQDTHTYSAELDRPDIKMATQISKIIS 193

Query: 1166 ENLYRSDLNFMRGVACVIPGTLEIEGRKKASELISESKYRQ----------------HPH 1209
               Y+     M     VI G  + E   +AS+L S+ KY++                   
Sbjct: 194  NAEYKKGQGIMNKEPAVI-GRPDFEHAVEASKLSSQIKYKEKFDNEMKDKKHHYNPLESA 252

Query: 1210 SFK---------------------YTAVTDTPNLL---HAKFSNQITNERLYKAAGEDAR 1245
            SF+                     +  V+D PNLL   H   ++++ + R YK   E+ +
Sbjct: 253  SFRQNQLAATLASNVKYKKDIQNMHDPVSDLPNLLFLDHVLKASKMLSGREYKKLFEENK 312

Query: 1246 HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIASD 1305
              Y       E +  K NA   S  +YKE +   + +     +E   +QA++ +  + S+
Sbjct: 313  GMYHFDADAVEHLHHKGNAVLQSQVKYKEEYEKNKGKPMLEFVETPSYQASKEAQKMQSE 372

Query: 1306 FLYRHDFVKERGKLIGPQSVRDD--PRIQHCRRMGQLQSELQYRRGATS--SQAQFHLPM 1361
             +Y+ DF KE   + G  S+  D  P   H + +  L  E +Y++   +        L  
Sbjct: 373  KVYKEDFEKE---IKGRSSLDLDKTPEFLHVKYITNLLREKEYKKDLENEIKGKGMELNS 429

Query: 1362 DMVHLVHAKNAQALASDHDYRTQYHK------FTALPEDLKMAWAKKAHALQSELRYKSD 1415
            +++ +  AK A  +AS+ +Y+             A  + L+M  AKKA  + SE  YK D
Sbjct: 430  EVLDIQRAKRASEMASEKEYKKDLESIIKGKGMQAGTDTLEMQHAKKAAEIASEKDYKRD 489

Query: 1416 L-IGMKGIGW-LALRSPQMESAKKAGELISETKYRKK-PDSIK---FTTVVDSPDLVHAK 1469
            L   +KG G  ++  +  ++ AKKA E+ S+ +Y+K   + IK       +D PD++ AK
Sbjct: 490  LETEIKGKGMQVSTDTLDVQRAKKASEMASQKQYKKDLENEIKGKGMQVSMDIPDILRAK 549

Query: 1470 NSYMHCNERMYRSGDAESLHRYTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDF 1529
             +    ++R Y+    + L  Y+ I D P+  R +    ++S   Y+        G+   
Sbjct: 550  RTSEIYSQRKYKDEAEKMLSNYSTIADTPEIQRIKTTQQNISAVFYKK-----EVGAGTA 604

Query: 1530 RLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEY 1589
              D+   +  + +++  S  +YKE             ++ D P +K      +  S+ +Y
Sbjct: 605  VKDSPEIERVKKNQQNISSVKYKEEIKH-------ATAISDPPELKRVKENQKNISNLQY 657

Query: 1590 KKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQKAHQL 1649
            K+   K+       +  P + + +R+Q+  S V Y+  L + T   +   L+ A++  + 
Sbjct: 658  KEQNYKAT----PVSMTPEIERVRRNQEQLSAVKYKGELQRGTAISDPPELKRAKENQKN 713

Query: 1650 QSDVKYKSDLNLTRGVGWTP 1669
             S+V Y+  L     +  TP
Sbjct: 714  ISNVYYRGQLGRATTLSVTP 733


>gi|239752495 PREDICTED: similar to nebulin [Homo sapiens]
          Length = 237

 Score =  159 bits (401), Expect = 3e-38
 Identities = 77/184 (41%), Positives = 118/184 (64%)

Query: 821  KYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYKKGFEDTKSQCHVSLDMVHL 880
            KYKE Y +  G  +G + +Q D +   ++  +K+QS+ EYKK +E +K   +  LDM+ +
Sbjct: 24   KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 881  VHARKAQHLATDVGYKTAEHHFTALPTDMKVEWAKKAYGLQSDNQYRADVKWMKGMGWVA 940
            V A+K Q L +D+ Y+   H +T LP    V  AKKAY LQSDN Y++D++W+KG+GW+ 
Sbjct: 84   VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143

Query: 941  TGSLNVEQAKKAGELISEKKYRQHPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGEN 1000
             GS+ V + K A  L++E+ YR  P+ALKFTSI DTPE++QA+I+  Q  +        N
Sbjct: 144  EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFN 203

Query: 1001 IKHH 1004
            ++H+
Sbjct: 204  VRHY 207



 Score =  145 bits (365), Expect = 4e-34
 Identities = 74/163 (45%), Positives = 106/163 (65%), Gaps = 4/163 (2%)

Query: 582 KYKEEYEKTKGKAMGTA----DSRLLHSLQIAKMSSEVEYKKGFEESKTRFHLPMDMVNI 637
           KYKE Y K  G  MG      D + + ++  AK+ S+ EYKK +E+SK   + P+DM++I
Sbjct: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 638 RHAKKAQTLASDLDYRKKLHEYTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLT 697
             AKK Q L SD+DYR  LH++T LP+      AKKAY LQS+  YK+DL W+KG+GWL 
Sbjct: 84  VQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLP 143

Query: 698 EGSLNLEQAKKAGQLVSEKNYRQRVDELKFTSVTDSSQMEHAK 740
           EGS+ + + K A  L++E+ YR + + LKFTS+ D+ ++  AK
Sbjct: 144 EGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAK 186



 Score =  142 bits (359), Expect = 2e-33
 Identities = 69/169 (40%), Positives = 108/169 (63%)

Query: 1060 ISDYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLD 1119
            +  YKYKE + K  G  +G R+L+DD     +++A  +QSD  YKK +E SK   + PLD
Sbjct: 20   VPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLD 79

Query: 1120 MAALVHAKKAQTLASNQDYKHPLPQYTSLAEDLRLSCAKKAHKLQSENLYRSDLNFMRGV 1179
            M ++V AKK Q L S+ DY++ L Q+T L +   +  AKKA+ LQS+NLY+SDL +++G+
Sbjct: 80   MMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGI 139

Query: 1180 ACVIPGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFS 1228
              +  G++E+   K A  L++E  YR  P + K+T++ DTP ++ AK +
Sbjct: 140  GWLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKIN 188



 Score =  130 bits (327), Expect = 1e-29
 Identities = 67/186 (36%), Positives = 115/186 (61%), Gaps = 1/186 (0%)

Query: 1306 FLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDMVH 1365
            + Y+  + K+ G  +G ++++DDP+        ++QS+ +Y++    S+   + P+DM+ 
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 1366 LVHAKNAQALASDHDYRTQYHKFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWL 1425
            +V AK  Q L SD DYR   H++T LP+   +  AKKA+ LQS+  YKSDL  +KGIGWL
Sbjct: 83   IVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWL 142

Query: 1426 ALRSPQMESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDA 1485
               S ++   K A  L++E  YR KP+++KFT++VD+P+++ AK + +  +E + +S D 
Sbjct: 143  PEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISE-VEKSRDN 201

Query: 1486 ESLHRY 1491
             ++  Y
Sbjct: 202  FNVRHY 207



 Score =  118 bits (296), Expect = 4e-26
 Identities = 61/163 (37%), Positives = 92/163 (56%), Gaps = 12/163 (7%)

Query: 1526 SYDFRLDAIPFQTARASREIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQS 1585
            +YD  L  +P             ++YKE + +  G  +G+R++ DDP+    ++  ++QS
Sbjct: 12   TYDLSLPEVP------------SYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQS 59

Query: 1586 DNEYKKDFAKSRSQFHSSTDQPGLLQAKRSQQLASDVHYRQPLPQPTCDPEQLGLRHAQK 1645
            D EYKK + KS+   ++  D   ++QAK+ Q L SD+ YR  L Q TC P+Q  +  A+K
Sbjct: 60   DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKK 119

Query: 1646 AHQLQSDVKYKSDLNLTRGVGWTPPGSYKVEMARRAAELANAR 1688
            A+ LQSD  YKSDL   +G+GW P GS +V   + A  L N R
Sbjct: 120  AYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVKNAQNLLNER 162



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 52/185 (28%), Positives = 80/185 (43%), Gaps = 10/185 (5%)

Query: 333 KYRQDFNKMKGAAHYHSLPAQDNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYCETPQ 392
           KY++ + K  G  H      QD+     A    K+ S+ EYKK  E S+G      +   
Sbjct: 24  KYKEGYRKQLGH-HMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 393 FRNVSKISKFTSDNKYKENYQNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYK--H 450
                K     SD  Y+ NY +    ++  +      + A K   L S+  YK+D +   
Sbjct: 83  IVQAKKCQVLVSDIDYR-NYLH----QWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLK 137

Query: 451 DIVDYNYPATLTPSYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHV 510
            I      +      + A  L  L +  YR   + LK++S+ DTP+++QAKINA Q+S V
Sbjct: 138 GIGWLPEGSVEVMRVKNAQNL--LNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEV 195

Query: 511 NYRAD 515
               D
Sbjct: 196 EKSRD 200



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 34/132 (25%), Positives = 62/132 (46%), Gaps = 8/132 (6%)

Query: 464 SYQTAMKLVP---LKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK 520
           +Y  ++  VP    K+   +Q    + + ++ D P+ V A   A+  S   Y+  YEK+K
Sbjct: 12  TYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSK 71

Query: 521 LNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASN 580
             +  P D+  +V+AK    L S++ Y+    +     +    D   ++ AK + +L S+
Sbjct: 72  GIHNTPLDMMSIVQAKKCQVLVSDIDYRNYLHQ-----WTCLPDQNDVIQAKKAYDLQSD 126

Query: 581 IKYKEEYEKTKG 592
             YK + E  KG
Sbjct: 127 NLYKSDLEWLKG 138



 Score = 39.3 bits (90), Expect = 0.034
 Identities = 44/175 (25%), Positives = 69/175 (39%), Gaps = 41/175 (23%)

Query: 652 YRKKLHE---YTVLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKK 708
           YRK+L     +  L +D K+ WA  A  +QS+ +YK      KG+               
Sbjct: 29  YRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGI--------------- 73

Query: 709 AGQLVSEKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDE 768
                               +  D   +  AKK Q L S + Y+      +HQ+T   D+
Sbjct: 74  ------------------HNTPLDMMSIVQAKKCQVLVSDIDYR----NYLHQWTCLPDQ 111

Query: 769 PLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVKYK 823
              +QA+      S+ LYKS  E  K  G+ L   S+  +  K  ++L +E  Y+
Sbjct: 112 NDVIQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYR 165



 Score = 38.9 bits (89), Expect = 0.044
 Identities = 55/242 (22%), Positives = 94/242 (38%), Gaps = 45/242 (18%)

Query: 1184 PGTLEIEGRKKASELISESKYRQHPHSFKYTAVTDTPNLLHAKFSNQITNERLYKAAGED 1243
            P T ++   +  S    E   +Q  H   +  + D P  + A  + +I ++R YK A E 
Sbjct: 10   PHTYDLSLPEVPSYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEK 69

Query: 1244 ARHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIA 1303
            ++  +   L +   ++AK     +SD  Y    RN   Q   L  +    QA +A  D+ 
Sbjct: 70   SKGIHNTPLDMMSIVQAKKCQVLVSDIDY----RNYLHQWTCLPDQNDVIQAKKAY-DLQ 124

Query: 1304 SDFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLPMDM 1363
            SD LY+                                S+L++ +G         LP   
Sbjct: 125  SDNLYK--------------------------------SDLEWLKGIG------WLPEGS 146

Query: 1364 VHLVHAKNAQALASDHDYRTQYH--KFTALPEDLKMAWAKKAHALQSELRYKSDLIGMKG 1421
            V ++  KNAQ L ++  YR +    KFT++ +  ++  AK      SE+    D   ++ 
Sbjct: 147  VEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRH 206

Query: 1422 IG 1423
             G
Sbjct: 207  YG 208



 Score = 37.7 bits (86), Expect = 0.098
 Identities = 41/176 (23%), Positives = 71/176 (40%), Gaps = 39/176 (22%)

Query: 407 KYKENYQNHMRGRYEGVGM---DRRTLHAMKVGSLASNVAYKADYKHDIVDYNYPATLTP 463
           KYKE Y+  + G + G      D +++ A+    + S+  YK  Y+     +N P  +  
Sbjct: 24  KYKEGYRKQL-GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 464 SYQTAMKLVPLKDANYRQSIDKLKYSSVTDTPQIVQAKINAQQLSHVNYRADYE------ 517
             Q     V + D +YR  + +  ++ + D   ++QAK      S   Y++D E      
Sbjct: 83  IVQAKKCQVLVSDIDYRNYLHQ--WTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIG 140

Query: 518 ---------------KNKLN------------YTLPQDVPQLVKAKTNAKLFSEVK 546
                          +N LN            +T   D P++++AK NA   SEV+
Sbjct: 141 WLPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEVE 196



 Score = 37.7 bits (86), Expect = 0.098
 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

Query: 192 EYKRGHDERISR---FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPA 248
           +YK G+ +++     F T+ D P+ + +   A++QSD  Y + YE+ +G  + P  +   
Sbjct: 24  KYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSI 83

Query: 249 YQIAKRANELASDVRY 264
            Q AK+   L SD+ Y
Sbjct: 84  VQ-AKKCQVLVSDIDY 98



 Score = 37.0 bits (84), Expect = 0.17
 Identities = 36/149 (24%), Positives = 52/149 (34%), Gaps = 44/149 (29%)

Query: 1379 HDYRTQYHK-------FTALPEDLKMAWAKKAHALQSELRYKSDLIGMKGIGWLALRSPQ 1431
            + Y+  Y K       F  L +D K  WA  A  +QS+  YK      KGI    L    
Sbjct: 23   YKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMS 82

Query: 1432 MESAKKAGELISETKYRKKPDSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAESLHRY 1491
            +  AKK   L+S+  YR                                       LH++
Sbjct: 83   IVQAKKCQVLVSDIDYRNY-------------------------------------LHQW 105

Query: 1492 TLIPDHPDFTRARLNALHLSDKVYRNSWE 1520
            T +PD  D  +A+      SD +Y++  E
Sbjct: 106  TCLPDQNDVIQAKKAYDLQSDNLYKSDLE 134



 Score = 36.2 bits (82), Expect = 0.28
 Identities = 29/90 (32%), Positives = 45/90 (50%), Gaps = 9/90 (10%)

Query: 293 QYGQGYPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPA 352
           Q  + Y + YE+ +G  + P  +    Q AKK   L SDI YR   ++      +  LP 
Sbjct: 58  QSDREYKKAYEKSKGIHNTPLDMMSIVQ-AKKCQVLVSDIDYRNYLHQ------WTCLPD 110

Query: 353 QDNLVLKQAQSVNKLVSEVEYKKDLESSRG 382
           Q++++  QA+    L S+  YK DLE  +G
Sbjct: 111 QNDVI--QAKKAYDLQSDNLYKSDLEWLKG 138



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 9/108 (8%)

Query: 138 LPDPEIVRMVEARKSLGEE----YTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEY 193
           LPD   V  ++A+K+   +    Y  D E  +G G  P        R K A  L ++  Y
Sbjct: 108 LPDQNDV--IQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEV-MRVKNAQNLLNERLY 164

Query: 194 KRGHDERISRFSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSF 241
           +   +    +F+++VDTPE++++K  A   S+V  + D    R  GS+
Sbjct: 165 RIKPEAL--KFTSIVDTPEVIQAKINAVQISEVEKSRDNFNVRHYGSY 210



 Score = 31.2 bits (69), Expect = 9.1
 Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 9/119 (7%)

Query: 476 DANYRQSIDKLK--YSSVTDTPQIVQAKINAQQLSHVNYRADYEKNKLN-YTLPQDVPQL 532
           D  Y+++ +K K  +++  D   IVQAK     +S ++YR     N L+ +T   D   +
Sbjct: 60  DREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLVSDIDYR-----NYLHQWTCLPDQNDV 114

Query: 533 VKAKTNAKLFSEVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591
           ++AK    L S+  YK   E  KG G+ +   ++ ++  K +  L +   Y+ + E  K
Sbjct: 115 IQAKKAYDLQSDNLYKSDLEWLKGIGW-LPEGSVEVMRVKNAQNLLNERLYRIKPEALK 172


>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
          Length = 270

 Score =  125 bits (313), Expect = 5e-28
 Identities = 70/198 (35%), Positives = 103/198 (52%), Gaps = 37/198 (18%)

Query: 1   MNVQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPK 60
           MN Q C+RCG  VYP EK++C+D+ WHK CFHCEVCKM L++NN+  ++KKPYC+AH PK
Sbjct: 1   MNPQ-CARCGKVVYPTEKVNCLDKYWHKGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPK 59

Query: 61  NNTFTSVYHTPLNLNVRTFPEAISGIHDQEDGEQCKSVFHWDMKSKDKEGAPNRQPLANE 120
             +FT+V  TP NL ++   E  S +  + D E+ K                        
Sbjct: 60  -QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESK------------------------ 94

Query: 121 RAYWTGYGEGNAWCPGALPDPEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQ 179
                  G G +        PE+ R+   ++ +   +Y ED+E+ +G+G  P +  P  +
Sbjct: 95  -------GRGFSI---VTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTE 144

Query: 180 RAKKANQLASQVEYKRGH 197
           R +K  Q+ S   YK  H
Sbjct: 145 RVRKNTQVVSDAAYKGVH 162



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 1/125 (0%)

Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233
           TP   R K+ ++L SQV+YKR  +E   R FS V DTPEL R K   +  S+V+Y ED+E
Sbjct: 68  TPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFE 127

Query: 234 QQRGKGSFPAMITPAYQIAKRANELASDVRYHQQYQKEMRGMAGPAIGAEGILTRECADQ 293
           + +G+G  P +  P  +  ++  ++ SD  Y   +   +     P I    +L       
Sbjct: 128 KTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQS 187

Query: 294 YGQGY 298
           + QGY
Sbjct: 188 HSQGY 192



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 49/154 (31%), Positives = 75/154 (48%), Gaps = 10/154 (6%)

Query: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263
           F+TV DTPE LR K  ++LQS V+Y  D+E+ +G+G      TP  Q  KR  E  S+V+
Sbjct: 62  FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 264 YHQQYQK-EMRGMA----GPAIGAEGILTRECADQYGQG-YPEEYEEHRGKGSFPAMITP 317
           YH+ ++K + RG       P        T+  +D   +G +P   E  R  G   A + P
Sbjct: 122 YHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLP 181

Query: 318 -AYQNAKKAHELASDIKYRQDFNKMKGAAHYHSL 350
            AYQ   ++H       ++   + M+   H  +L
Sbjct: 182 GAYQ---QSHSQGYGYMHQTSVSSMRSMQHSPNL 212



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 35/91 (38%), Positives = 54/91 (59%), Gaps = 9/91 (9%)

Query: 511 NYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKGFEMK 562
           NY+  YEK         K ++T   D P+ ++ K  ++L S+VKYK  +E++KG+GF + 
Sbjct: 43  NYKG-YEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIV 101

Query: 563 LDAMSLLAAKASGELASNIKYKEEYEKTKGK 593
            D   L   K + E  SN+KY E++EKTKG+
Sbjct: 102 TDTPELQRLKRTQEQISNVKYHEDFEKTKGR 132



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 32/101 (31%), Positives = 58/101 (57%), Gaps = 1/101 (0%)

Query: 485 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 543
           K  +++V DTP+ ++ K  ++  S V Y+ D+E++K   +++  D P+L + K   +  S
Sbjct: 59  KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 544 EVKYKEGWEKTKGKGFEMKLDAMSLLAAKASGELASNIKYK 584
            VKY E +EKTKG+GF   +D       + + ++ S+  YK
Sbjct: 119 NVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 35/108 (32%), Positives = 49/108 (45%), Gaps = 2/108 (1%)

Query: 1002 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061
            K  +T  AD PE L  K  +   S+ +YK  + + +  G+ +  D    Q  K + E IS
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEH 1109
            + KY E FEK KG+  G   + DD         T + SD  YK    H
Sbjct: 119  NVKYHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 12/163 (7%)

Query: 698 EGSLNLEQAKKAGQLVSEKNYRQR------VDELKFTSVTDSSQMEHAKKSQELQSGVAY 751
           +G  + E  K A  + + K Y ++        +  FT+V D+ +    K+  ELQS V Y
Sbjct: 27  KGCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKY 86

Query: 752 KAGNEQSVHQ-YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAA 810
           K   E+S  + ++I  D P   + +     +S   Y   +E  K +GF   +D       
Sbjct: 87  KRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERV 146

Query: 811 KAKRDLASEVKYKEDYER-----SRGKLIGAKDVQGDSQMSHS 848
           +    + S+  YK  +        R  +I A  + G  Q SHS
Sbjct: 147 RKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQQSHS 189



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 7/117 (5%)

Query: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199
           PE +R+ +  +   + +Y  D+E+ +G+G      TP  QR K+  +  S V+Y    ++
Sbjct: 69  PENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEK 128

Query: 200 RISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDY----EQQRGKGSFPAMITP-AYQ 250
              R F+ VVD P   R +   Q+ SD  Y   +    E  R  G   A + P AYQ
Sbjct: 129 TKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPVLPGAYQ 185



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 2/103 (1%)

Query: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304
            +  +T     PE +R K  +   S  +YK  +   + +G+ +  +    Q  + + +  S
Sbjct: 59   KQSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQIS 118

Query: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYR 1347
            +  Y  DF K +G+   P  V DDP  +  R+  Q+ S+  Y+
Sbjct: 119  NVKYHEDFEKTKGRGFTP--VVDDPVTERVRKNTQVVSDAAYK 159



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 39/165 (23%), Positives = 73/165 (44%), Gaps = 32/165 (19%)

Query: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 666
           ++ KM+  +   KG+E+            N  + K++ T  +D             PE++
Sbjct: 33  EVCKMALNMNNYKGYEKKP--------YCNAHYPKQSFTTVADT------------PENL 72

Query: 667 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725
           +    K+   LQS+++YK D    KG G+ +   +  L++ K+  + +S   Y +  ++ 
Sbjct: 73  RL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKT 129

Query: 726 K---FTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKD 767
           K   FT V D    E  +K+ ++ S  AYK      VH + +  D
Sbjct: 130 KGRGFTPVVDDPVTERVRKNTQVVSDAAYK-----GVHPHIVEMD 169



 Score = 45.4 bits (106), Expect = 5e-04
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 4/98 (4%)

Query: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINYC-ETPQFRNVSKISKFTSDNKYKENY 412
           +NL LKQ    ++L S+V+YK+D E S+G   +   +TP+ + + +  +  S+ KY E++
Sbjct: 70  ENLRLKQQ---SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDF 126

Query: 413 QNHMRGRYEGVGMDRRTLHAMKVGSLASNVAYKADYKH 450
           +      +  V  D  T    K   + S+ AYK  + H
Sbjct: 127 EKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPH 164



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 2/100 (2%)

Query: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821
           +T   D P  L+ +  +   S+  YK  +E  K +GF +  D+      K  ++  S VK
Sbjct: 62  FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 822 YKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQSELEYK 861
           Y ED+E+++G+  G   V  D       + +++ S+  YK
Sbjct: 122 YHEDFEKTKGR--GFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 28/132 (21%), Positives = 57/132 (43%), Gaps = 7/132 (5%)

Query: 1185 GTLEIEGRKKASELISESKYRQHPH------SFKYTAVTDTPNLLHAKFSNQITNERLYK 1238
            G    E  K A  + +   Y + P+         +T V DTP  L  K  +++ ++  YK
Sbjct: 28   GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87

Query: 1239 AAGEDAR-HEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAAR 1297
               E+++   +++    PE  R K     +S+ +Y E +   + +G+   ++    +  R
Sbjct: 88   RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147

Query: 1298 ASGDIASDFLYR 1309
             +  + SD  Y+
Sbjct: 148  KNTQVVSDAAYK 159



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 7/94 (7%)

Query: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1450
            PE+L++   K+   LQS+++YK D    KG G+ +   +P+++  K+  E IS  KY + 
Sbjct: 69   PENLRL---KQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHED 125

Query: 1451 PDSIK---FTTVVDSPDLVHAKNSYMHCNERMYR 1481
             +  K   FT VVD P     + +    ++  Y+
Sbjct: 126  FEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 34/109 (31%), Positives = 51/109 (46%), Gaps = 6/109 (5%)

Query: 557 KGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKGKAMG--TADSRLLHSLQIAKMSSE 614
           + F    D    L  K   EL S +KYK ++E++KG+     T    L    +  +  S 
Sbjct: 60  QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISN 119

Query: 615 VEYKKGFEESKTRFHLPM--DMVNIRHAKKAQTLASDLDYRKKLHEYTV 661
           V+Y + FE++K R   P+  D V  R  K  Q + SD  Y K +H + V
Sbjct: 120 VKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQ-VVSDAAY-KGVHPHIV 166



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 32/132 (24%), Positives = 59/132 (44%), Gaps = 7/132 (5%)

Query: 942  GSLNVEQAKKAGELISEKKYRQHP------DALKFTSIKDTPEMVQARI-SYTQAVDRLY 994
            G  + E  K A  + + K Y + P          FT++ DTPE ++ +  S  Q+  +  
Sbjct: 28   GCFHCEVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYK 87

Query: 995  REQGENIKHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAK 1054
            R+  E+    ++   D PE+   K     IS  +Y E + K +  G+   +D    +  +
Sbjct: 88   RDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVR 147

Query: 1055 ASGEIISDYKYK 1066
             + +++SD  YK
Sbjct: 148  KNTQVVSDAAYK 159



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 37/166 (22%), Positives = 76/166 (45%), Gaps = 25/166 (15%)

Query: 607 QIAKMSSEVEYKKGFEESKTR-FHLPMDMVNIRHAKKAQTLASDLDYRKKLHE-----YT 660
           Q +++ S+V+YK+ FEESK R F +  D   ++  K+ Q   S++ Y +   +     +T
Sbjct: 76  QQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFT 135

Query: 661 VLPEDMKTQWAKKAYGLQSELQYKADLAWMKGVGWLTEGSLNLEQAKKAGQLVS------ 714
            + +D  T+  +K   + S+  YK     +            +E  ++ G +V+      
Sbjct: 136 PVVDDPVTERVRKNTQVVSDAAYKGVHPHI------------VEMDRRPGIIVAPVLPGA 183

Query: 715 -EKNYRQRVDELKFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSV 759
            ++++ Q    +  TSV+    M+H+   +  ++   Y A +E  V
Sbjct: 184 YQQSHSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDEDEV 229



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 31/127 (24%), Positives = 56/127 (44%), Gaps = 7/127 (5%)

Query: 1433 ESAKKAGELISETKYRKKP------DSIKFTTVVDSPDLVHAKNSYMHCNERMYRSGDAE 1486
            E  K A  + +   Y KKP          FTTV D+P+ +  K      ++  Y+    E
Sbjct: 33   EVCKMALNMNNYKGYEKKPYCNAHYPKQSFTTVADTPENLRLKQQSELQSQVKYKRDFEE 92

Query: 1487 SLHR-YTLIPDHPDFTRARLNALHLSDKVYRNSWEQTRAGSYDFRLDAIPFQTARASREI 1545
            S  R ++++ D P+  R +     +S+  Y   +E+T+   +   +D    +  R + ++
Sbjct: 93   SKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQV 152

Query: 1546 ASDFRYK 1552
             SD  YK
Sbjct: 153  VSDAAYK 159



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 3/111 (2%)

Query: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855
           + F    D+   L  K + +L S+VKYK D+E S+G+  G   V    ++    +  +  
Sbjct: 60  QSFTTVADTPENLRLKQQSELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQI 117

Query: 856 SELEYKKGFEDTKSQCHVS-LDMVHLVHARKAQHLATDVGYKTAEHHFTAL 905
           S ++Y + FE TK +     +D       RK   + +D  YK    H   +
Sbjct: 118 SNVKYHEDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYKGVHPHIVEM 168



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 35/126 (27%), Positives = 56/126 (44%), Gaps = 18/126 (14%)

Query: 1565 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1623
            + +V D P          LQS  +YK+DF +S+ + F   TD P L + KR+Q+  S+V 
Sbjct: 62   FTTVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVK 121

Query: 1624 YRQPLPQ-------PTCDPEQLGLRHAQKAHQLQSDVKYKS------DLNLTRGVGWTP- 1669
            Y +   +       P  D         +K  Q+ SD  YK       +++   G+   P 
Sbjct: 122  YHEDFEKTKGRGFTPVVDDPV--TERVRKNTQVVSDAAYKGVHPHIVEMDRRPGIIVAPV 179

Query: 1670 -PGSYK 1674
             PG+Y+
Sbjct: 180  LPGAYQ 185



 Score = 37.4 bits (85), Expect = 0.13
 Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHS 1602
            E+ S  +YK  F   +G   G+  V D P ++         S+ +Y +DF K++ + F  
Sbjct: 79   ELQSQVKYKRDFEESKGR--GFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTP 136

Query: 1603 STDQPGLLQAKRSQQLASDVHYR 1625
              D P   + +++ Q+ SD  Y+
Sbjct: 137  VVDDPVTERVRKNTQVVSDAAYK 159



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 21/160 (13%)

Query: 1095 TSLQSDVNYKKGFEHSKAQ-FHLPLDMAALVHAKKAQTLASNQDYKHPLPQ-----YTSL 1148
            + LQS V YK+ FE SK + F +  D   L   K+ Q   SN  Y     +     +T +
Sbjct: 78   SELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYHEDFEKTKGRGFTPV 137

Query: 1149 AEDLRLSCAKKAHKLQSENLYRSDLNFMRGVACVIPGTLEIEGRKK--ASELISESKYRQ 1206
             +D      +K  ++ S+  Y+           V P  +E++ R     + ++  +  + 
Sbjct: 138  VDDPVTERVRKNTQVVSDAAYKG----------VHPHIVEMDRRPGIIVAPVLPGAYQQS 187

Query: 1207 HPHSFKYTAVTDTPNLLHAKFSNQITNERL---YKAAGED 1243
            H   + Y   T   ++   + S  +   R    Y A  ED
Sbjct: 188  HSQGYGYMHQTSVSSMRSMQHSPNLRTYRAMYDYSAQDED 227



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 6/96 (6%)

Query: 1324 SVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQ-FHLPMDMVHLVHAKNAQALASDHDYR 1382
            +V D P     ++  +LQS+++Y+R    S+ + F +  D   L   K  Q   S+  Y 
Sbjct: 64   TVADTPENLRLKQQSELQSQVKYKRDFEESKGRGFSIVTDTPELQRLKRTQEQISNVKYH 123

Query: 1383 TQYHK-----FTALPEDLKMAWAKKAHALQSELRYK 1413
              + K     FT + +D      +K   + S+  YK
Sbjct: 124  EDFEKTKGRGFTPVVDDPVTERVRKNTQVVSDAAYK 159


>gi|5453710 LIM and SH3 protein 1 [Homo sapiens]
          Length = 261

 Score =  105 bits (263), Expect = 3e-22
 Identities = 46/91 (50%), Positives = 64/91 (70%), Gaps = 1/91 (1%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65
          C+RCG  VYP EK++C+D+ WHKACFHCE CKM L++ N+  ++KKPYC+AH PK  +FT
Sbjct: 5  CARCGKIVYPTEKVNCLDKFWHKACFHCETCKMTLNMKNYKGYEKKPYCNAHYPK-QSFT 63

Query: 66 SVYHTPLNLNVRTFPEAISGIHDQEDGEQCK 96
           V  TP NL ++   E  S +  +E+ E+ K
Sbjct: 64 MVADTPENLRLKQQSELQSQVRYKEEFEKNK 94



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 7/126 (5%)

Query: 204 FSTVVDTPELLRSKAGAQLQSDVRYTEDYEQQRGKGSFPAMITPAYQIAKRANELASDVR 263
           F+ V DTPE LR K  ++LQS VRY E++E+ +GKG      TP  Q  K+  +  S+++
Sbjct: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 264 YHQQYQKEMRGMAGPAIGAEGILTRECADQYGQGYP---EEYEEHRGKGSFPAMITPAYQ 320
           YH++++K   G +    G EG+       Q G  Y    E+ + H    S P    P  Q
Sbjct: 122 YHEEFEKSRMGPS----GGEGMEPERRDSQDGSSYRRPLEQQQPHHIPTSAPVYQQPQQQ 177

Query: 321 NAKKAH 326
              +++
Sbjct: 178 PVAQSY 183



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 36/93 (38%), Positives = 55/93 (59%), Gaps = 9/93 (9%)

Query: 507 LSHVNYRADYEKN--------KLNYTLPQDVPQLVKAKTNAKLFSEVKYKEGWEKTKGKG 558
           L+  NY+  YEK         K ++T+  D P+ ++ K  ++L S+V+YKE +EK KGKG
Sbjct: 39  LNMKNYKG-YEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG 97

Query: 559 FEMKLDAMSLLAAKASGELASNIKYKEEYEKTK 591
           F +  D   L   K + +  SNIKY EE+EK++
Sbjct: 98  FSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 9/140 (6%)

Query: 1002 KHHYTPTADLPEVLLAKLNAMNISETRYKESWSKLRDGGYKLRLDALPFQAAKASGEIIS 1061
            K  +T  AD PE L  K  +   S+ RYKE + K +  G+ +  D    Q  K + + IS
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 1062 DYKYKEAFEKMKGQMLGSRSLEDDISLAHSVYATSLQSDVNYKKGFEHSKAQFHLPLDMA 1121
            + KY E FEK +    G   +E +            Q   +Y++  E  +   H+P    
Sbjct: 119  NIKYHEEFEKSRMGPSGGEGMEPE--------RRDSQDGSSYRRPLEQQQPH-HIPTSAP 169

Query: 1122 ALVHAKKAQTLASNQDYKHP 1141
                 ++     S   YK P
Sbjct: 170  VYQQPQQQPVAQSYGGYKEP 189



 Score = 48.5 bits (114), Expect = 6e-05
 Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 6/82 (7%)

Query: 485 KLKYSSVTDTPQIVQAKINAQQLSHVNYRADYEKNK-LNYTLPQDVPQLVKAKTNAKLFS 543
           K  ++ V DTP+ ++ K  ++  S V Y+ ++EKNK   +++  D P+L + K      S
Sbjct: 59  KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 544 EVKYKEGWEKTK-----GKGFE 560
            +KY E +EK++     G+G E
Sbjct: 119 NIKYHEEFEKSRMGPSGGEGME 140



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 1/63 (1%)

Query: 175 TPAYQRAKKANQLASQVEYKRGHDERISR-FSTVVDTPELLRSKAGAQLQSDVRYTEDYE 233
           TP   R K+ ++L SQV YK   ++   + FS V DTPEL R K      S+++Y E++E
Sbjct: 68  TPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFE 127

Query: 234 QQR 236
           + R
Sbjct: 128 KSR 130



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 22/69 (31%), Positives = 36/69 (52%)

Query: 762 YTISKDEPLFLQARANAANLSEKLYKSSWENQKAKGFELRLDSLTFLAAKAKRDLASEVK 821
           +T+  D P  L+ +  +   S+  YK  +E  K KGF +  D+      K  +D  S +K
Sbjct: 62  FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 822 YKEDYERSR 830
           Y E++E+SR
Sbjct: 122 YHEEFEKSR 130



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 9/95 (9%)

Query: 540 KLFSEVKYKEGWEKTK-------GKGFEMKLDAMSLLAAKASGELASNIKYKEEYEKTKG 592
           K+   +K  +G+EK          + F M  D    L  K   EL S ++YKEE+EK KG
Sbjct: 36  KMTLNMKNYKGYEKKPYCNAHYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKG 95

Query: 593 KAMG-TADSRLLHSLQIAK-MSSEVEYKKGFEESK 625
           K     AD+  L  ++  +   S ++Y + FE+S+
Sbjct: 96  KGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 41.2 bits (95), Expect = 0.009
 Identities = 18/45 (40%), Positives = 27/45 (60%)

Query: 298 YPEEYEEHRGKGSFPAMITPAYQNAKKAHELASDIKYRQDFNKMK 342
           Y EE+E+++GKG      TP  Q  KK  +  S+IKY ++F K +
Sbjct: 86  YKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKSR 130



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 9/116 (7%)

Query: 1245 RHEYTMTLGLPEFIRAKTNAANLSDARYKESWRNLRAQGYKLTIEALPFQAARASGDIAS 1304
            +  +TM    PE +R K  +   S  RYKE +   + +G+ +  +    Q  + + D  S
Sbjct: 59   KQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQIS 118

Query: 1305 DFLYRHDFVKERGKLIGPQSVRDDPRIQHCRRMGQLQSELQYRRGATSSQAQFHLP 1360
            +  Y  +F K R    G + +  + R          Q    YRR     Q   H+P
Sbjct: 119  NIKYHEEFEKSRMGPSGGEGMEPERR--------DSQDGSSYRR-PLEQQQPHHIP 165



 Score = 40.8 bits (94), Expect = 0.012
 Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 4/74 (5%)

Query: 354 DNLVLKQAQSVNKLVSEVEYKKDLESSRGHSINY-CETPQFRNVSKISKFTSDNKYKENY 412
           +NL LKQ    ++L S+V YK++ E ++G   +   +TP+ + + K     S+ KY E +
Sbjct: 70  ENLRLKQQ---SELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEF 126

Query: 413 QNHMRGRYEGVGMD 426
           +    G   G GM+
Sbjct: 127 EKSRMGPSGGEGME 140



 Score = 36.6 bits (83), Expect = 0.22
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 1544 EIASDFRYKEAFLRDRGLQIGYRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQFHSS 1603
            E+ S  RYKE F +++G   G+  V D P ++         S+ +Y ++F KSR      
Sbjct: 79   ELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQISNIKYHEEFEKSRM---GP 133

Query: 1604 TDQPGLLQAKRSQQLASDVHYRQPLPQ 1630
            +   G+   +R  Q  S   YR+PL Q
Sbjct: 134  SGGEGMEPERRDSQDGSS--YRRPLEQ 158



 Score = 35.8 bits (81), Expect = 0.37
 Identities = 24/78 (30%), Positives = 40/78 (51%), Gaps = 4/78 (5%)

Query: 305 HRGKGSFPAMI-TPAYQNAKKAHELASDIKYRQDFNKMKGAAHYHSLPAQDNLVLKQAQS 363
           H  K SF  +  TP     K+  EL S ++Y+++F K KG     S+ A D   L++ + 
Sbjct: 56  HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKG--FSVVA-DTPELQRIKK 112

Query: 364 VNKLVSEVEYKKDLESSR 381
               +S ++Y ++ E SR
Sbjct: 113 TQDQISNIKYHEEFEKSR 130



 Score = 35.4 bits (80), Expect = 0.49
 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 4/60 (6%)

Query: 1392 PEDLKMAWAKKAHALQSELRYKSDLIGMKGIGW-LALRSPQMESAKKAGELISETKYRKK 1450
            PE+L++   K+   LQS++RYK +    KG G+ +   +P+++  KK  + IS  KY ++
Sbjct: 69   PENLRL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEE 125



 Score = 34.3 bits (77), Expect = 1.1
 Identities = 19/73 (26%), Positives = 39/73 (53%), Gaps = 2/73 (2%)

Query: 796 KGFELRLDSLTFLAAKAKRDLASEVKYKEDYERSRGKLIGAKDVQGDSQMSHSLQMSKLQ 855
           + F +  D+   L  K + +L S+V+YKE++E+++GK  G   V    ++    +     
Sbjct: 60  QSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGK--GFSVVADTPELQRIKKTQDQI 117

Query: 856 SELEYKKGFEDTK 868
           S ++Y + FE ++
Sbjct: 118 SNIKYHEEFEKSR 130



 Score = 33.9 bits (76), Expect = 1.4
 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 1/77 (1%)

Query: 964  HPDALKFTSIKDTPEMVQARISYTQAVDRLYREQGENIKHH-YTPTADLPEVLLAKLNAM 1022
            H     FT + DTPE ++ +          Y+E+ E  K   ++  AD PE+   K    
Sbjct: 56   HYPKQSFTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQD 115

Query: 1023 NISETRYKESWSKLRDG 1039
             IS  +Y E + K R G
Sbjct: 116  QISNIKYHEEFEKSRMG 132



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%)

Query: 1565 YRSVDDDPRMKHFLNVGRLQSDNEYKKDFAKSRSQ-FHSSTDQPGLLQAKRSQQLASDVH 1623
            +  V D P          LQS   YK++F K++ + F    D P L + K++Q   S++ 
Sbjct: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 1624 YRQPLPQPTCDP 1635
            Y +   +    P
Sbjct: 122  YHEEFEKSRMGP 133



 Score = 32.7 bits (73), Expect = 3.1
 Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 4/60 (6%)

Query: 141 PEIVRMVEARKSLGE-EYTEDYEQPRGKGSFPAMITPAYQRAKKANQLASQVEYKRGHDE 199
           PE +R+ +  +   +  Y E++E+ +GKG      TP  QR KK     S ++Y   H+E
Sbjct: 69  PENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKY---HEE 125



 Score = 31.6 bits (70), Expect = 7.0
 Identities = 38/182 (20%), Positives = 77/182 (42%), Gaps = 28/182 (15%)

Query: 607 QIAKMSSEVEYKKGFEESKTRFHLPMDMVNIRHAKKAQTLASDLDYRKKLHEYTVLPEDM 666
           +  KM+  ++  KG+E+            N  + K++ T+ +D             PE++
Sbjct: 33  ETCKMTLNMKNYKGYEKKP--------YCNAHYPKQSFTMVADT------------PENL 72

Query: 667 KTQWAKKAYGLQSELQYKADLAWMKGVGW-LTEGSLNLEQAKKAGQLVSEKNYRQRVDEL 725
           +    K+   LQS+++YK +    KG G+ +   +  L++ KK    +S   Y +  ++ 
Sbjct: 73  RL---KQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIKYHEEFEKS 129

Query: 726 KFTSVTDSSQMEHAKKSQELQSGVAYKAGNEQSVHQYTISKDEPLFLQARANAANLSEKL 785
           +    +    ME  ++  + Q G +Y+   EQ    + I    P++ Q +      S   
Sbjct: 130 RM-GPSGGEGMEPERR--DSQDGSSYRRPLEQQ-QPHHIPTSAPVYQQPQQQPVAQSYGG 185

Query: 786 YK 787
           YK
Sbjct: 186 YK 187



 Score = 31.6 bits (70), Expect = 7.0
 Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 1/69 (1%)

Query: 1213 YTAVTDTPNLLHAKFSNQITNERLYKAAGEDARHE-YTMTLGLPEFIRAKTNAANLSDAR 1271
            +T V DTP  L  K  +++ ++  YK   E  + + +++    PE  R K     +S+ +
Sbjct: 62   FTMVADTPENLRLKQQSELQSQVRYKEEFEKNKGKGFSVVADTPELQRIKKTQDQISNIK 121

Query: 1272 YKESWRNLR 1280
            Y E +   R
Sbjct: 122  YHEEFEKSR 130


>gi|116517305 cysteine-rich protein 3 [Homo sapiens]
          Length = 204

 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 21/50 (42%), Positives = 28/50 (56%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55
          C RC   V+ AEK+S + + WH+ C  CE C  +LS      H  +PYCH
Sbjct: 5  CPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCH 54



 Score = 51.2 bits (121), Expect = 9e-06
 Identities = 19/50 (38%), Positives = 26/50 (52%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55
           C  CG  VY AEK+  + + WH+ C  C+ C   L+  +   H   PYCH
Sbjct: 124 CPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCH 173


>gi|4503049 cysteine-rich protein 2 [Homo sapiens]
          Length = 208

 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 21/50 (42%), Positives = 27/50 (54%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55
          C +C   VY AEK+S + + WHK C  CE C   L+      H  KP+CH
Sbjct: 5  CPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCH 54



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 20/50 (40%), Positives = 27/50 (54%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55
           C RC   VY AEK++ + + WH+ C  CE C   L+      H  +PYCH
Sbjct: 126 CPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCH 175


>gi|189083753 cysteine and glycine-rich protein 3 [Homo sapiens]
          Length = 194

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 22/58 (37%), Positives = 27/58 (46%)

Query: 4   QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61
           + C RCG  VY AEK+    + WHK CF C +C   L   N      + YC     KN
Sbjct: 118 EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKN 175



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 19/49 (38%), Positives = 26/49 (53%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
          C  C   VY AE+I C  + +HK CFHC  C+  L      +H+ + YC
Sbjct: 10 CGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC 58


>gi|4502893 cysteine and glycine-rich protein 3 [Homo sapiens]
          Length = 194

 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 22/58 (37%), Positives = 27/58 (46%)

Query: 4   QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61
           + C RCG  VY AEK+    + WHK CF C +C   L   N      + YC     KN
Sbjct: 118 EKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYCKVCYAKN 175



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 19/49 (38%), Positives = 26/49 (53%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
          C  C   VY AE+I C  + +HK CFHC  C+  L      +H+ + YC
Sbjct: 10 CGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC 58


>gi|4503047 cysteine-rich protein 1 (intestinal) [Homo sapiens]
          Length = 77

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 18/50 (36%), Positives = 28/50 (56%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCH 55
          C +C   VY AE+++ + + WH+ C  CE C   L+      H+ KPYC+
Sbjct: 4  CPKCNKEVYFAERVTSLGKDWHRPCLKCEKCGKTLTSGGHAEHEGKPYCN 53


>gi|4503101 cysteine and glycine-rich protein 2 [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 23/58 (39%), Positives = 27/58 (46%)

Query: 4   QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61
           + CSRCG  VY AEKI    + WHK CF C  C   L        + + YC     KN
Sbjct: 117 EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKN 174



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 18/49 (36%), Positives = 26/49 (53%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
          C  CG  VY AE++ C  + +H+ CF C VC+  L       H ++ YC
Sbjct: 10 CGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC 58


>gi|4758086 cysteine and glycine-rich protein 1 isoform 1 [Homo
           sapiens]
          Length = 193

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 24/56 (42%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKN 61
           C RC   VY AEK+    + WHKACF C  C   L          + YC     KN
Sbjct: 119 CPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKN 174



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 19/49 (38%), Positives = 25/49 (51%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
          C  C   VY AE++ C    +HK+CF C VCK  L       H ++ YC
Sbjct: 10 CGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC 58


>gi|165905591 LIM domain and actin binding 1 isoform c [Homo
           sapiens]
          Length = 600

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 18/54 (33%), Positives = 27/54 (50%)

Query: 4   QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57
           + C  C   VYP E++    Q++H +CF C  C   LS+  + S   + YC  H
Sbjct: 229 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 282


>gi|165905589 LIM domain and actin binding 1 isoform a [Homo
           sapiens]
          Length = 760

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 18/54 (33%), Positives = 27/54 (50%)

Query: 4   QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57
           + C  C   VYP E++    Q++H +CF C  C   LS+  + S   + YC  H
Sbjct: 389 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 442


>gi|7705373 LIM domain and actin binding 1 isoform b [Homo sapiens]
          Length = 759

 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 18/54 (33%), Positives = 27/54 (50%)

Query: 4   QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57
           + C  C   VYP E++    Q++H +CF C  C   LS+  + S   + YC  H
Sbjct: 388 ETCVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPH 441


>gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Homo
           sapiens]
          Length = 938

 Score = 45.1 bits (105), Expect = 6e-04
 Identities = 20/52 (38%), Positives = 26/52 (50%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57
           C  C   VYP E +    Q +HK+CF C  C   LS+ N+ S   + YC  H
Sbjct: 402 CILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPH 453


>gi|7662330 actin binding LIM protein family, member 3 [Homo
           sapiens]
          Length = 683

 Score = 43.9 bits (102), Expect = 0.001
 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 11/80 (13%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAHNPKNNTFT 65
           C+ C   +   + +  +D+ WH +CF C+ C ++L+   ++S    PYC           
Sbjct: 151 CAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILT-GEYISKDGVPYCE---------- 199

Query: 66  SVYHTPLNLNVRTFPEAISG 85
           S YH    +   T    ISG
Sbjct: 200 SDYHAQFGIKCETCDRYISG 219


>gi|221316627 cysteine and glycine-rich protein 1 isoform 2 [Homo
          sapiens]
          Length = 140

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 19/49 (38%), Positives = 25/49 (51%)

Query: 6  CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
          C  C   VY AE++ C    +HK+CF C VCK  L       H ++ YC
Sbjct: 10 CGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC 58


>gi|13386490 LIM domain containing 2 [Homo sapiens]
          Length = 127

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 17/54 (31%), Positives = 29/54 (53%)

Query: 4  QPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHAH 57
          + C+ C   VYP E++     I+H +CF C+ C   LS+ ++ +   + YC  H
Sbjct: 38 ETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAALHGEFYCKPH 91


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 15/31 (48%), Positives = 20/31 (64%)

Query: 24  QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           Q WH  CFHC+ C + L+   FV HQ++ YC
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 25  IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           +WHK CF C  CK ++   +F    +  YC
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           C +C   +  +  I+  DQ WH  CF C  C   L+   F + + + YC
Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 15/31 (48%), Positives = 20/31 (64%)

Query: 24  QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           Q WH  CFHC+ C + L+   FV HQ++ YC
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 25  IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           +WHK CF C  CK ++   +F    +  YC
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           C +C   +  +  I+  DQ WH  CF C  C   L+   F + + + YC
Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 15/31 (48%), Positives = 20/31 (64%)

Query: 24  QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           Q WH  CFHC+ C + L+   FV HQ++ YC
Sbjct: 272 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 302



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 25  IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           +WHK CF C  CK ++   +F    +  YC
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 179



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           C +C   +  +  I+  DQ WH  CF C  C   L+   F + + + YC
Sbjct: 191 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 238


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 15/31 (48%), Positives = 20/31 (64%)

Query: 24  QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           Q WH  CFHC+ C + L+   FV HQ++ YC
Sbjct: 259 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 289



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 25  IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           +WHK CF C  CK ++   +F    +  YC
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 166



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           C +C   +  +  I+  DQ WH  CF C  C   L+   F + + + YC
Sbjct: 178 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 225


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 15/31 (48%), Positives = 20/31 (64%)

Query: 24  QIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           Q WH  CFHC+ C + L+   FV HQ++ YC
Sbjct: 243 QSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 11/30 (36%), Positives = 16/30 (53%)

Query: 25  IWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           +WHK CF C  CK ++   +F    +  YC
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYC 150



 Score = 33.1 bits (74), Expect = 2.4
 Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 6   CSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYC 54
           C +C   +  +  I+  DQ WH  CF C  C   L+   F + + + YC
Sbjct: 162 CVKCNKAI-TSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 3   VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56
           ++ C  CG  +   + +  +D+ WH  CF C+ C  +L+   ++S    PYC A
Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202


>gi|153792514 actin binding LIM protein family, member 2 isoform 6
           [Homo sapiens]
          Length = 521

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 3   VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56
           ++ C  CG  +   + +  +D+ WH  CF C+ C  +L+   ++S    PYC A
Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202


>gi|194272204 actin binding LIM protein family, member 2 isoform 5
           [Homo sapiens]
          Length = 531

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%)

Query: 3   VQPCSRCGYGVYPAEKISCIDQIWHKACFHCEVCKMMLSVNNFVSHQKKPYCHA 56
           ++ C  CG  +   + +  +D+ WH  CF C+ C  +L+   ++S    PYC A
Sbjct: 150 LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNA-EYISKDGLPYCEA 202


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,130,600
Number of Sequences: 37866
Number of extensions: 2734076
Number of successful extensions: 10161
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 6941
Number of HSP's gapped (non-prelim): 506
length of query: 1730
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1614
effective length of database: 13,855,062
effective search space: 22362070068
effective search space used: 22362070068
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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