BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|13129104 coiled-coil domain containing 86 [Homo sapiens] (360 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|13129104 coiled-coil domain containing 86 [Homo sapiens] 728 0.0 gi|4505101 microtubule-associated protein 7 [Homo sapiens] 67 3e-11 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 66 6e-11 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 65 1e-10 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 64 3e-10 gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 62 6e-10 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 62 1e-09 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 60 2e-09 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 60 2e-09 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 60 2e-09 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 60 2e-09 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 60 3e-09 gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 60 4e-09 gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 60 4e-09 gi|21328446 hormone-sensitive lipase [Homo sapiens] 59 9e-09 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 58 1e-08 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 58 1e-08 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 58 2e-08 gi|110431370 espin [Homo sapiens] 57 2e-08 gi|151301053 RNA binding motif protein 33 [Homo sapiens] 56 4e-08 gi|33356148 formin-like 1 [Homo sapiens] 56 4e-08 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 56 6e-08 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 55 7e-08 gi|54860079 nadrin isoform 1 [Homo sapiens] 55 1e-07 gi|54860105 nadrin isoform 2 [Homo sapiens] 55 1e-07 gi|150170670 piccolo isoform 2 [Homo sapiens] 55 1e-07 gi|150378539 piccolo isoform 1 [Homo sapiens] 55 1e-07 gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre... 54 2e-07 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 54 2e-07 gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 54 2e-07 >gi|13129104 coiled-coil domain containing 86 [Homo sapiens] Length = 360 Score = 728 bits (1878), Expect = 0.0 Identities = 360/360 (100%), Positives = 360/360 (100%) Query: 1 MDTPLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPE 60 MDTPLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPE Sbjct: 1 MDTPLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPE 60 Query: 61 RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP 120 RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP Sbjct: 61 RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP 120 Query: 121 SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLE 180 SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLE Sbjct: 121 SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLE 180 Query: 181 LTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 LTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP Sbjct: 181 LTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 Query: 241 KSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQ 300 KSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQ Sbjct: 241 KSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQ 300 Query: 301 RRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAKI 360 RRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAKI Sbjct: 301 RRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAKI 360 >gi|4505101 microtubule-associated protein 7 [Homo sapiens] Length = 749 Score = 66.6 bits (161), Expect = 3e-11 Identities = 78/337 (23%), Positives = 143/337 (42%), Gaps = 35/337 (10%) Query: 17 ESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPR----L 72 E L S TRRA+ SNP+ R+P R+ L P + PG+PR L Sbjct: 299 ERENVLFLTSGTRRAVSP--SNPK-ARQPA------RSRLWLPSKSLPHLPGTPRPTSSL 349 Query: 73 QQGAGLESPQG--QPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQD 130 G+ +P P PG P +++ + +E ++ PE P+ +P AP + Sbjct: 350 PPGSVKAAPAQVRPPSPGNIRPVKRE-VKVEPEKKDPEKEPQKVANEPSLKGRAPLVKVE 408 Query: 131 QGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPR 190 + + E + E+ P AP + P P S AP P P+ P + P + + Sbjct: 409 EATV-EERTPAEPEVGPAAPA--MAPAPASAPAPASAPAPAPVPT-PAMVSAPSSTVNAS 464 Query: 191 GQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRS 250 + S E T K+R + ++ ++E K + + RV ++R+ Sbjct: 465 ASVKTSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERT 524 Query: 251 KKRFSQML----------QDKPLRTSWQRKMKERQERKLA---KDFARHLEEEKERRRQE 297 +R + +++ R + +R ++ER+E + A K+ + EE ER RQE Sbjct: 525 TRREEESRRLEAEQAREKEEQLQRQAEERALREREEAERAQRQKEEEARVREEAERVRQE 584 Query: 298 KKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKK 334 +++ + RLE +++ E ++++ + + KK Sbjct: 585 REKHFQREEQERLERKKRLE--EIMKRTRRTEATDKK 619 Score = 38.1 bits (87), Expect = 0.012 Identities = 40/149 (26%), Positives = 76/149 (51%), Gaps = 24/149 (16%) Query: 203 ETVTGGFGAKKRKGSSSQAPASK--------KLNKEELPVIPKGKPKSGRVWKDRSKKRF 254 ET + + +K +SS+ PAS NK + P + + + R+ ++R ++R Sbjct: 21 ETAPDSYKVQDKKNASSR-PASAISGQNNNHSGNKPDPPPVLRVDDRQ-RLARERREERE 78 Query: 255 SQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKER---RRQEKKQRRA---ENLKR 308 Q+ + + W ER+ER + + +HLEE K+R +RQ++++RRA E ++ Sbjct: 79 KQLAAREIV---WL----EREERA-RQHYEKHLEERKKRLEEQRQKEERRRAAVEEKRRQ 130 Query: 309 RLENERKAEVVQVIRNPAKLKRAKKKQLR 337 RLE +++ V R + ++ K+K R Sbjct: 131 RLEEDKERHEAVVRRTMERSQKPKQKHNR 159 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 65.9 bits (159), Expect = 6e-11 Identities = 80/362 (22%), Positives = 144/362 (39%), Gaps = 34/362 (9%) Query: 20 ESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLE 79 E+ + V ++ E +S PE+ + P + SPE+ SP + A + Sbjct: 617 EAKSPVKEEAKSPAEVKS-PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675 Query: 80 SPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELA 139 SP+ P A + + +SP ++ SPE + K EEA + + + E Sbjct: 676 SPEKAKSPVKAEAKSPEKA--KSPVKEEAKSPEKAKSPVK--EEAKSPEKAKSPVKEEAK 731 Query: 140 QNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 ++ +P + + P SPE PE P E SP + Sbjct: 732 TPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE----EARSPADKFPEKAKS 787 Query: 200 PAGETVTGGFGAKKRKGSSSQAPASKKLNKEEL--PVIPKGKPKSGRVWKD--------- 248 P E V AK ++AP + KEE+ PV + KP+ +V + Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847 Query: 249 ----RSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAE 304 +++++ ++ P + + + K++E++E + K +E +KE +KK E Sbjct: 848 PATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907 Query: 305 -------NLKRRLENERKAEVVQVIRNPAKLKRAKK---KQLRSIEKRDTLALLQKQPPQ 354 +K + + K EV + + AK K K K+ + EK+DT K+P + Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 967 Query: 355 QP 356 +P Sbjct: 968 KP 969 Score = 51.2 bits (121), Expect = 1e-06 Identities = 68/351 (19%), Positives = 134/351 (38%), Gaps = 24/351 (6%) Query: 14 LRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQ 73 ++ +S E + V ++ + V E EET+ + + + E K G + Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQV--TEEVTEEEEKEAKEEEGKEEEGGEEEE 493 Query: 74 QGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGV 133 G E + P AASP+++ +SP ++ SP + K ++P Sbjct: 494 AEGGEEETKSPPAEEAASPEKE----AKSPVKEEAKSPAEAKSPEKEEAKSP-------- 541 Query: 134 LASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQ---QAPGPEPSQPLLELTPRAPGSPR 190 +E+ ++ +P + + PP SPE + + PE ++ + ++P + Sbjct: 542 --AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAK 599 Query: 191 GQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRS 250 + P E AK +++PA K + E+ K + KS K Sbjct: 600 SPEKAKS--PVKEEAKSPAEAKSPVKEEAKSPAEVK-SPEKAKSPTKEEAKSPEKAKSPE 656 Query: 251 KKRFSQMLQDK-PLRTSWQRKMKERQERKL-AKDFARHLEEEKERRRQEKKQRRAENLKR 308 K+ + K P++ + K + K AK + KE + +K + + Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA 716 Query: 309 RLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAK 359 + + K+ V + + P K K K++ +S EK + + + P AK Sbjct: 717 KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAK 767 Score = 48.9 bits (115), Expect = 7e-06 Identities = 71/349 (20%), Positives = 140/349 (40%), Gaps = 22/349 (6%) Query: 17 ESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGA 76 +SP + S + + E +P E + P + A + SPE+ SP + A Sbjct: 539 KSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK--SPAKEEAKSPA 596 Query: 77 GLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSP---ESPRCQPKPSEEAPKCSQDQGV 133 +SP+ P + + +SP ++ SP +SP P++E K + Sbjct: 597 EAKSPEKAKSP--VKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654 Query: 134 LASELAQNKEEL-TPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQ 192 E A++ E+ +P + + P SP +A PE ++ ++ ++P + Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVK---AEAKSPEKAKSPVKEEAKSPEKAKSP 711 Query: 193 -HEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSK 251 E +K P ++ K S +K K + P K K+ V +K Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE----KAKTLDVKSPEAK 767 Query: 252 KRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLE 311 + + + + K ++E K + L+E+ + EK+ + E +K ++ Sbjct: 768 TPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDA--KAPEKEIPKKEEVKSPVK 825 Query: 312 NERKAEVVQVIRNPAKLKRAKKKQL-RSIEKRDTLALLQKQPPQQPAAK 359 E K + V+V P K + K ++ EK+D+ +++ P++ A K Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDS---KKEEAPKKEAPK 871 Score = 45.8 bits (107), Expect = 6e-05 Identities = 76/354 (21%), Positives = 136/354 (38%), Gaps = 38/354 (10%) Query: 17 ESPESLTSVSRTRRALVEFESNPE-ETREPGSPPSVQRAGLGSPERPPKTSPG---SPRL 72 E E+ T+ E ++PE E + P + A SPE+ SP SP Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549 Query: 73 QQGAGLESPQGQPEPGAASPQRQQDLHLESPQ--RQPEYSPESPRCQPKPSEEAPKCSQD 130 + E + PE A SP++++ +SP + PE + + + K EA + Sbjct: 550 AKSPAKEEAKSPPE--AKSPEKEE---AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA 604 Query: 131 QGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPR 190 + + E E +P + + P SPE ++P E ++ +P SP Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK---AKSPTKEEAK-----SPEKAKSP- 655 Query: 191 GQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRS 250 + E +K P ++ K S +K K + PV K + KS K Sbjct: 656 -EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV--KEEAKSPEKAKSPV 712 Query: 251 KKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRL 310 K+ ++ + K ++E K + ++EE + + K +A+ L + Sbjct: 713 KEE---------AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK- 762 Query: 311 ENERKAEVVQVIRNPA-----KLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAK 359 E K + R+PA K K K++++S EK + + P++ K Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816 Score = 38.9 bits (89), Expect = 0.007 Identities = 66/282 (23%), Positives = 111/282 (39%), Gaps = 41/282 (14%) Query: 17 ESPESLTSVSRTRRA----LVEFESNP--EETREPGSPPSVQRAGLGSPER--PPKTSPG 68 +SPE+ T R+ E +P EE + P S + +PE+ P K Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVK 821 Query: 69 SPRLQQGAGLESPQGQP--EPGAASPQRQQDLHLESPQRQPEYSPESPRCQ-PKPSEEAP 125 SP ++ E PQ EP + + + ++ +++ E+P+ + PKP E Sbjct: 822 SPVKEE----EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEK 877 Query: 126 KCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRA 185 K + S++ KEE A + P P P + +P + E+ + Sbjct: 878 KEPAVEKPKESKVEAKKEE----AEDKKKVPTPEKEAPAKVEVKEDAKPKEKT-EVAKKE 932 Query: 186 PGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRV 245 P + + EPSKP A+K+ +A KK KEE P+ KPK+ Sbjct: 933 PDDAKAK-EPSKP------------AEKK-----EAAPEKKDTKEEKAKKPEEKPKTEAK 974 Query: 246 WKDRSK---KRFSQMLQDKPLRTSWQRKMKERQERKLAKDFA 284 K+ K K S+ +K ++S + + K +D A Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKA 1016 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 64.7 bits (156), Expect = 1e-10 Identities = 63/227 (27%), Positives = 85/227 (37%), Gaps = 31/227 (13%) Query: 40 EETREPGSPPSVQRA----GLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQ 95 +++R P SPP + G P+ PP PG P+ G PQG P PG Sbjct: 106 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164 Query: 96 QDLHLESPQRQPEYSPESPRCQ--PKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ-- 151 Q + R P P+ P Q +P P + QG + + PG PQ Sbjct: 165 QGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 224 Query: 152 -----------HQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPP 200 P P P P G Q GP P P+ P P+G ++P PPP Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG----KPQGP-PPQGGNKPQGPPP 279 Query: 201 AG--ETVTGGFGAKKRKGSS----SQAPASKKLNKEELPVIPKGKPK 241 G + G+K R S Q P + N+ + P P GKP+ Sbjct: 280 PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326 Score = 62.8 bits (151), Expect = 5e-10 Identities = 61/220 (27%), Positives = 82/220 (37%), Gaps = 32/220 (14%) Query: 45 PGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPG---AASPQRQQDLHLE 101 PG P G P+ PP PG P+ G PQG P PG PQ + Sbjct: 54 PGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR 112 Query: 102 SPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ---------- 151 SP +P+ P P+ +P P + QG + + PG PQ Sbjct: 113 SPPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKS 170 Query: 152 ---HQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGG 208 P P P P G Q GP P P+ P P+G ++P PPP G+ G Sbjct: 171 RSSRSPPGKPQGPPPQGGNQPQGPPPPPG----KPQGP-PPQGGNKPQGPPPPGKP-QGP 224 Query: 209 FGAKKRKGSSSQAPASKKL-------NKEELPVIPKGKPK 241 K S+++P K N+ + P P GKP+ Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 264 Score = 60.1 bits (144), Expect = 3e-09 Identities = 59/215 (27%), Positives = 76/215 (35%), Gaps = 27/215 (12%) Query: 45 PGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQ 104 PG P G P+ PP PG P+ G PQG P PG Q + Sbjct: 177 PGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSA 235 Query: 105 RQPEYSPESPRCQ--PKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ----------- 151 R P P+ P Q +P P + QG + + PG PQ Sbjct: 236 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 295 Query: 152 --HQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAG--ETVTG 207 P P P P G Q GP P P+ P P+G ++P PPP G + Sbjct: 296 SSRSPPGKPQGPPPQGGNQPQGPPPPPG----KPQGP-PPQGGNKPQGPPPPGKPQGPPP 350 Query: 208 GFGAKKRKGSS----SQAPASKKLNKEELPVIPKG 238 G+K R S Q P ++ N + P P G Sbjct: 351 QGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAG 385 Score = 57.0 bits (136), Expect = 3e-08 Identities = 57/203 (28%), Positives = 75/203 (36%), Gaps = 41/203 (20%) Query: 46 GSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQR 105 G+P G P+ PP + PG P+ G PQG P P PQ P Sbjct: 34 GNPQGAPPQGGNKPQGPP-SPPGKPQGPPPQGGNQPQGPPPP-PGKPQ--------GPPP 83 Query: 106 QPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYP 165 Q P+ P KP P Q + +P +P P P P P Sbjct: 84 QGGNKPQGPPPPGKPQGPPP--------------QGDKSRSPRSP----PGKPQGPPPQG 125 Query: 166 GQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASK 225 G Q GP P P+ P P+G ++P PPP G+ G K SS++P K Sbjct: 126 GNQPQGPPPPPG----KPQGP-PPQGGNKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGK 179 Query: 226 KL-------NKEELPVIPKGKPK 241 N+ + P P GKP+ Sbjct: 180 PQGPPPQGGNQPQGPPPPPGKPQ 202 Score = 54.3 bits (129), Expect = 2e-07 Identities = 48/164 (29%), Positives = 61/164 (37%), Gaps = 9/164 (5%) Query: 45 PGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQ 104 PG P G P+ PP PG P+ G PQG P PG Q Sbjct: 239 PGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS 297 Query: 105 RQPEYSPESPRCQ--PKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPE 162 R P P+ P Q +P P + QG NK + P + Q PP G + Sbjct: 298 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGGSK 355 Query: 163 PYPGQQAPGPEPSQPLLE-LTPRAPGSPRGQHEPSKP--PPAGE 203 + PG P E P+ P P G + P +P PPAG+ Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGN-PQQPQAPPAGQ 398 Score = 53.5 bits (127), Expect = 3e-07 Identities = 48/168 (28%), Positives = 60/168 (35%), Gaps = 29/168 (17%) Query: 37 SNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQ 96 + P+ PG P G GS R ++ PG P+ G PQG P P Sbjct: 272 NKPQGPPPPGKPQGPPPQG-GSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG------- 323 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQH---- 152 PQ P P+ P P + P+ QG S A++ G PQ Sbjct: 324 -----KPQGPPPQGGNKPQGPPPPGK--PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNN 376 Query: 153 -QLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 Q PP P P Q P +P P PR P R PS+PP Sbjct: 377 PQGPPPPAGGNPQQPQAPPAGQPQGP-----PRPPQGGR----PSRPP 415 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 63.5 bits (153), Expect = 3e-10 Identities = 64/221 (28%), Positives = 86/221 (38%), Gaps = 42/221 (19%) Query: 40 EETREPGSPPSVQRA----GLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPG---AASP 92 +++R P SPP + G P+ PP PG P+ G PQG P PG P Sbjct: 85 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143 Query: 93 QRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ- 151 Q + SP +P+ P P+ +P P + QG + + PG PQ Sbjct: 144 QGDKSRSPRSPPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201 Query: 152 ----------HQLPP-VPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPP 200 Q PP P P P G Q GP P P+ P P+G ++P PPP Sbjct: 202 PPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPG----KPQGP-PPQGGNKPQGPPP 256 Query: 201 AGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPK 241 G+ G + GS SQ+ S P GKP+ Sbjct: 257 PGKPQ----GPPAQGGSKSQSARS-----------PPGKPQ 282 Score = 62.8 bits (151), Expect = 5e-10 Identities = 62/218 (28%), Positives = 82/218 (37%), Gaps = 32/218 (14%) Query: 46 GSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAAS---PQRQQDLHLES 102 G+P G P+ PP PG P+ G PQG P PG PQ + S Sbjct: 34 GNPQGPSPQGGNKPQGPPPP-PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92 Query: 103 PQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ----------- 151 P +P+ P P+ +P P + QG + + PG PQ Sbjct: 93 PPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRS 150 Query: 152 -HQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFG 210 P P P P G Q GP P P+ P P+G +P PPP G+ G Sbjct: 151 PRSPPGKPQGPPPQGGNQPQGPPPPPG----KPQGP-PPQGGKKPQGPPPPGK--PQGPP 203 Query: 211 AKKRKGSSSQAPASKKL-------NKEELPVIPKGKPK 241 + K SSQ+P K N+ + P P GKP+ Sbjct: 204 PQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241 Score = 57.4 bits (137), Expect = 2e-08 Identities = 48/173 (27%), Positives = 67/173 (38%), Gaps = 28/173 (16%) Query: 40 EETREPGSPPSVQRA----GLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAAS---P 92 +++R P SPP + G P+ PP PG P+ G + PQG P PG P Sbjct: 146 DKSRSPRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGPPPQGGKKPQGPPPPGKPQGPPP 204 Query: 93 QRQQDLHLESPQRQPEYSPESPRCQPK---PSEEAPKCSQDQGVLASELAQNKEELTPGA 149 Q + +SP +P+ P QP+ P P+ QG NK + P Sbjct: 205 QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-------GNKPQGPPPP 257 Query: 150 PQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAG 202 + Q PP G + + PG P+ P G + PPPAG Sbjct: 258 GKPQGPPAQGGSKSQSARSPPGK----------PQGPPQQEGNNPQGPPPPAG 300 Score = 50.8 bits (120), Expect = 2e-06 Identities = 57/213 (26%), Positives = 69/213 (32%), Gaps = 25/213 (11%) Query: 58 SPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQ 117 S E P G+P+ G PQG P P PQ P Q P+ P Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPP-PGKPQ--------GPPPQGGNKPQGPPPP 74 Query: 118 PKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPE---PYPGQQAPGPEP 174 KP P+ + + + G PP PG P+ P G + GP P Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134 Query: 175 -----SQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNK 229 P R+P SP G +P PPP G G K KK Sbjct: 135 PGKPQGPPPQGDKSRSPRSPPG--KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQG 192 Query: 230 EELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKP 262 P P+G P G K R SQ KP Sbjct: 193 PPPPGKPQGPPPQG------DKSRSSQSPPGKP 219 Score = 47.0 bits (110), Expect = 3e-05 Identities = 45/166 (27%), Positives = 61/166 (36%), Gaps = 22/166 (13%) Query: 45 PGSPPSVQRAGLGSPERPP---KTSPGSPRLQQGAGLESPQGQPE---PGAASPQRQQDL 98 PG P G P+ PP K P+ + +SP G+P+ P + + Sbjct: 176 PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP 235 Query: 99 HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQH-----Q 153 PQ P P+ P P + P+ QG S+ A++ G PQ Q Sbjct: 236 PPGKPQGPPPQGGNKPQGPPPPGK--PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQ 293 Query: 154 LPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 PP P P Q P +P P PR P R PS+PP Sbjct: 294 GPPPPAGGNPQQPQAPPAGQPQGP-----PRPPQGGR----PSRPP 330 Score = 39.7 bits (91), Expect = 0.004 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 9/81 (11%) Query: 37 SNPEETREPGSP--PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQR 94 + P+ PG P P Q R P P P Q+G +PQG P P +PQ+ Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG---NNPQGPPPPAGGNPQQ 305 Query: 95 QQDLHLESPQRQPEYSPESPR 115 Q P QP+ P P+ Sbjct: 306 PQ----APPAGQPQGPPRPPQ 322 >gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo sapiens] Length = 956 Score = 62.4 bits (150), Expect = 6e-10 Identities = 70/269 (26%), Positives = 111/269 (41%), Gaps = 34/269 (12%) Query: 88 GAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLAS---ELAQNKEE 144 G R+ D SP+ PE + C P +E S+ G+L + ++ Sbjct: 189 GCGGAGRRGDSQECSPRSCPELTSGPRMC---PRKEQDSWSEAGGILFKGKVPMVVLQDI 245 Query: 145 LTPGAPQ-HQLPPVPGSPEPYPGQQA--PGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA 201 L PQ LP P P + PE L + +P S P PP Sbjct: 246 LAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPP-- 303 Query: 202 GETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDK 261 K+ S+S P S L + + KG + ++ R ++R + L+ Sbjct: 304 -----------KQHSSTSPFPTSTPLRRITKKFV-KGSTEKNKLRLQRDQERLGKQLK-- 349 Query: 262 PLRTSWQRKMKERQERKLAKDFARHLEEE------KERRRQEKKQRRAENLKRRLENERK 315 LR + K K ++E K AK+ A+ +EE KERR + +K + + K+RL+ ER+ Sbjct: 350 -LRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERR 408 Query: 316 AEVVQVIRNPAKLKRAK--KKQLRSIEKR 342 E + + + KR K +K+LR EKR Sbjct: 409 KERQEALEAKLEEKRKKEEEKRLREEEKR 437 Score = 30.4 bits (67), Expect = 2.6 Identities = 23/98 (23%), Positives = 47/98 (47%), Gaps = 10/98 (10%) Query: 262 PLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQV 321 PLR ++ +K E+ + L+ ++ER ++ K R K +L+ E K Sbjct: 317 PLRRITKKFVKGSTEKNKLR-----LQRDQERLGKQLKLRAEREEKEKLKEEAKR----- 366 Query: 322 IRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAK 359 + AK K+ ++K+L+ E+R+ +K+ ++ K Sbjct: 367 AKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLK 404 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 61.6 bits (148), Expect = 1e-09 Identities = 72/303 (23%), Positives = 116/303 (38%), Gaps = 50/303 (16%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQ--------GAGLESPQGQ-PE 86 E++ ++ P S P + RPP+T PG P + AG P G P+ Sbjct: 372 EADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPD 431 Query: 87 PGA--ASPQRQQDLHLESPQRQPEYSPE----SPRCQPKPSEEAPKCSQDQGVLASELAQ 140 G P +D QR+ + S E R + + EE + +++ +E + Sbjct: 432 RGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLK 491 Query: 141 NKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAP---GSPRGQHEPSK 197 +E GAP +L P +P P P P P+ P P AP +P + EP + Sbjct: 492 RLDEKF-GAPDKRLKAEPAAPPAAP--STPAPPPAVPKELPAPPAPPPASAPTPETEPEE 548 Query: 198 P---PPAGETVT------------GGFGAKKRKGSSSQAPASKKLNKEE----------- 231 P PPA T T GG + GS +P +L +E Sbjct: 549 PAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPP 608 Query: 232 -LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEE 290 P +PK +PK + R SQ L + S + + +Q+ +L K +H ++ Sbjct: 609 TTPPVPKVEPKGDGIGPTRQPP--SQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQ 666 Query: 291 KER 293 ++ Sbjct: 667 HQQ 669 Score = 45.1 bits (105), Expect = 1e-04 Identities = 46/167 (27%), Positives = 66/167 (39%), Gaps = 36/167 (21%) Query: 35 FESNPEETREPGSPPSVQRAGLGSPER-PPKTSPGSPRLQ-QGAGLESPQGQPEPGAASP 92 FE++P E + P + G PE PP T+P P+++ +G G+ + P G P Sbjct: 584 FEASPVEPQLPS------KEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYP 637 Query: 93 QRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQH 152 + Q+ L PR Q + E+ K Q + Q+++ P P Sbjct: 638 KYQKSL--------------PPRFQRQQQEQLLKQQQQH-----QWQQHQQGSAPPTPVP 678 Query: 153 QLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 PP P + P QAP P P L P A G P P PP Sbjct: 679 PSPPQPVTLGAVPAPQAPPPPPK----ALYPGALGRP-----PPMPP 716 Score = 37.7 bits (86), Expect = 0.016 Identities = 48/180 (26%), Positives = 70/180 (38%), Gaps = 11/180 (6%) Query: 3 TPLRRSR----RLGGLR-PESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLG 57 +P RSR R GL P P S ++V R + + SNP ++ + S ++ + Sbjct: 1435 SPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVI---HSNPAGIQQALAQLSSRQGSVT 1491 Query: 58 SPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQ 117 +P P+ PG P+ QG P + EP + D H E P +PR Sbjct: 1492 APGGHPRHKPGLPQAPQGPS-PRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDS 1550 Query: 118 PKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQP 177 S PK +++ EL Q +E L P L P P P + G E P Sbjct: 1551 AGVSPFPPK-RRERPPRKPELLQ-EESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTP 1608 Score = 37.0 bits (84), Expect = 0.027 Identities = 51/216 (23%), Positives = 78/216 (36%), Gaps = 13/216 (6%) Query: 16 PESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQG 75 P P LTS R+A E + P PP A P P +PG P + Sbjct: 800 PAEPRPLTSP--LRQAADEDDKGMRSETPPVPPPPPYLASY--PGFPENGAPGPPISR-- 853 Query: 76 AGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKC--SQDQGV 133 LE P +P P + P+++P + P+ + + S QG Sbjct: 854 FPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGP 913 Query: 134 LASELAQNKEEL---TPGAPQHQLPP-VPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSP 189 E PG+ + +PP PG+P G P P++ + EL P+ Sbjct: 914 PPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTK-VEELPPKPLEQG 972 Query: 190 RGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASK 225 +P KP P T G K+ + + +PA + Sbjct: 973 DETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR 1008 Score = 35.4 bits (80), Expect = 0.080 Identities = 41/188 (21%), Positives = 64/188 (34%), Gaps = 40/188 (21%) Query: 122 EEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLEL 181 EE + S ++G A+ + + + + P G P + P P+ + Sbjct: 344 EEDGRDSDEEG------AEGHRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSR 397 Query: 182 TPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPK 241 P P P PP G G +G P ++ P P Sbjct: 398 PPETEPGPPAPKPPLPPPHRGP--AGNWG-----------PPGDYPDRGGPPCKPPAPED 444 Query: 242 SGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQR 301 W+ R K+ S++ LA + AR EE+ERR QE+++ Sbjct: 445 EDEAWRQRRKQSSSEI--------------------SLAVERARRRREEEERRMQEERRA 484 Query: 302 R-AENLKR 308 AE LKR Sbjct: 485 ACAEKLKR 492 Score = 32.7 bits (73), Expect = 0.52 Identities = 57/222 (25%), Positives = 85/222 (38%), Gaps = 41/222 (18%) Query: 74 QGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGV 133 +G G P P P + E+ EY R + + SE + + Sbjct: 1066 RGGGTGGPNHPPAPRGRTAS-------ETRSEGSEYEEIPKRRRQRGSETGSETHE---- 1114 Query: 134 LASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLE----LTPRAPGSP 189 S+LA + +E P + L VP +P P PG P P P++ TPR S Sbjct: 1115 --SDLAPSDKE-APTPKEGTLTQVPLAPPP-PGAP-PSPAPARFTARGGRVFTPRGVPSR 1169 Query: 190 RGQHEPSKPPPAGETVTGGFGAKK----RKGSSSQAPASKKLNKEEL------PVIPKGK 239 RG+ +PPP + G K +K + P SK+ KE+L PV G Sbjct: 1170 RGR-GGGRPPP--QVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGS 1226 Query: 240 PKSGRVW-----KDRSKKRFSQMLQDKPLRTSWQRKMKERQE 276 V + R ++ QDKP R R++K+ +E Sbjct: 1227 NGGSNVGMEDGERPRRRRHGRAQQQDKPPRF---RRLKQERE 1265 Score = 32.3 bits (72), Expect = 0.68 Identities = 53/217 (24%), Positives = 67/217 (30%), Gaps = 51/217 (23%) Query: 50 SVQRAGLGSPERPPKTS--PGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQP 107 S QR G+ R P GS G G P G+ PG + S R P Sbjct: 1386 SSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRS--RPP 1443 Query: 108 EYSPESPRCQPKPSEEAPKCSQDQGVLAS---------ELAQNKEELT---------PGA 149 E P P P + DQ + ++ +L+ + +T PG Sbjct: 1444 EERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGL 1503 Query: 150 PQHQLPPVPGSPEPYPGQQAPGPEPSQPLLEL----------TP---------------R 184 PQ P P P Y Q+ S P E TP R Sbjct: 1504 PQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRER 1563 Query: 185 APGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQA 221 P P E S PPP + GF K +G QA Sbjct: 1564 PPRKPELLQEESLPPPH----SSGFLGSKPEGPGPQA 1596 Score = 31.6 bits (70), Expect = 1.2 Identities = 51/208 (24%), Positives = 66/208 (31%), Gaps = 41/208 (19%) Query: 33 VEFESNPEETREPGSPPSVQRAGL-GSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAAS 91 V+ + + + P S S GL G+ E PPK GS L E P G P Sbjct: 1653 VDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLN-AVPCEGPPGSEPPRRPP 1711 Query: 92 PQRQQDLHLESPQRQP------------------EYSPESPRCQPKPSEEAPKCSQDQG- 132 P E P+ QP E P P +P P + +D Sbjct: 1712 PAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDL 1771 Query: 133 --VLASELAQNKE---ELTPGAPQHQ----LPPVPGSPEPYPGQQAPG---PEPSQPLLE 180 V+ L KE +T P + LP S EP G PEPS Sbjct: 1772 RLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSGHCVPEPSSSGQR 1831 Query: 181 LTPRAPGSPRGQHEPSKPPPAGETVTGG 208 L P G P+ ++GG Sbjct: 1832 LYPEVFYGSAG--------PSSSQISGG 1851 Score = 30.0 bits (66), Expect = 3.4 Identities = 42/185 (22%), Positives = 64/185 (34%), Gaps = 14/185 (7%) Query: 20 ESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLE 79 +SL V+ RR + G+ P+V K P+ + + Sbjct: 45 QSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQ 104 Query: 80 SPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCS------QDQGV 133 P+ QP P + +P Q P+R P +PE+ P + + S D G Sbjct: 105 PPESQPLPASQTPASNQ------PKRPPA-APENTPLVPSGVKSWAQASVTHGAHGDGGR 157 Query: 134 LASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQH 193 +S L++ E P Q + E +Q+ GP PS T G RG Sbjct: 158 ASSLLSRFSREEFP-TLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPD 216 Query: 194 EPSKP 198 E P Sbjct: 217 ELEGP 221 Score = 28.5 bits (62), Expect = 9.8 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 10/66 (15%) Query: 145 LTPGAP-QHQLPPVPGSPEPYP--GQQAPGPEPSQPLLELTPRAPGSPRGQHEPS---KP 198 L GAP Q L P+ S P G P P P+ P L L P P PS +P Sbjct: 1970 LPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGP----ALQPPSLAVRP 2025 Query: 199 PPAGET 204 PPA T Sbjct: 2026 PPAPAT 2031 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 60.5 bits (145), Expect = 2e-09 Identities = 89/379 (23%), Positives = 133/379 (35%), Gaps = 73/379 (19%) Query: 33 VEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQG--------- 83 V+ +S P P PSVQ+ P PP P P QQ P Sbjct: 948 VKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTH 1007 Query: 84 --QPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQN 141 QP P PQ QQ H Q+ P P P+ Q +P+ + L + Sbjct: 1008 IQQPPP----PQGQQPPHPPPGQQPPPPQPAKPQ-QVIQHHHSPRHHKSDPYSTGHLREA 1062 Query: 142 KEELTPGAPQ--------HQLPPVPGSPEPYPGQQAPGPEPSQPLL-------------- 179 L +PQ HQ PP +A QPL+ Sbjct: 1063 PSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRS 1122 Query: 180 -----ELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPV 234 L P P P P P E G + AP +K++ Sbjct: 1123 EPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ 1182 Query: 235 IPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTS------------WQRKMKERQERKLA-K 281 PK + K ++ ++ ++Q P S ++R +E++ER+ A K Sbjct: 1183 EPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALK 1242 Query: 282 DFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEK 341 A H E+EKER RQE+ + R + + LE R+A + A+++Q + ++ Sbjct: 1243 AQAEHAEKEKERLRQERMRSRED--EDALEQARRAH-----------EEARRRQEQQQQQ 1289 Query: 342 RDTLALLQKQPPQQPAAKI 360 R Q+Q QQ AA + Sbjct: 1290 RQE----QQQQQQQQAAAV 1304 Score = 41.2 bits (95), Expect = 0.001 Identities = 43/180 (23%), Positives = 68/180 (37%), Gaps = 31/180 (17%) Query: 82 QGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQN 141 +G+ E G A P + P+ ++P+ P P + P + +L Sbjct: 181 RGRKETGTAKPGVSTVPNTTQASTPPQ--TQTPQPNPPPVQATP---HPFPAVTPDLIVQ 235 Query: 142 KEELT--PGAPQHQLPPVPGSPEPYPGQQAPGPEPSQ---PLLELTPRAPGSPRGQ---- 192 +T P P PPVP P+P P AP P+P Q P++ TP+ + +G Sbjct: 236 TPVMTVVPPQPLQTPPPVPPQPQPPP---APAPQPVQSHPPIIAATPQPVKTKKGVKRKA 292 Query: 193 -----------HEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPK 241 HEP PP +T G ++R+ S P K + + P+ K Sbjct: 293 DTTTPTTIDPIHEPPSLPPEPKTTKLG---QRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349 Score = 40.8 bits (94), Expect = 0.002 Identities = 46/199 (23%), Positives = 65/199 (32%), Gaps = 29/199 (14%) Query: 16 PESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQG 75 P+ PE T + A+V SPP++ A P RP + P Sbjct: 840 PQPPEHSTPPHLNQHAVV-------------SPPALHNALPQQPSRPSNRAAALPPKPAR 886 Query: 76 AGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLA 135 SP P P Q + +P P + ++ K +L Sbjct: 887 PPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP 946 Query: 136 SELAQNKEELTPGAPQH--------QLPPVPGSPEPYPGQQAPGPEPSQPLLELTP---- 183 S Q++ P H Q PP P P+P P Q P +P + L P Sbjct: 947 SVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP-VHLQPMQFS 1005 Query: 184 ---RAPGSPRGQHEPSKPP 199 + P P+GQ P PP Sbjct: 1006 THIQQPPPPQGQQPPHPPP 1024 Score = 38.1 bits (87), Expect = 0.012 Identities = 41/161 (25%), Positives = 55/161 (34%), Gaps = 14/161 (8%) Query: 44 EPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESP 103 E +PP + + + SP P P P P A SP Q L P Sbjct: 844 EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP 903 Query: 104 QRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEP 163 P P + + P S + +L Q + TP P ++ P P P Sbjct: 904 ---PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQL-QKVQPPTPLLPSVKVQSQPPPPLP 959 Query: 164 YPGQQAPGPEPS-QPLLELTPRAPGSPRGQHEPS---KPPP 200 P P PS Q L+ P P P+ Q P +PPP Sbjct: 960 ------PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP 994 Score = 37.4 bits (85), Expect = 0.021 Identities = 44/200 (22%), Positives = 70/200 (35%), Gaps = 30/200 (15%) Query: 19 PESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGL 78 P +L + R + + + P+ + S + G S E + S + Sbjct: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE 720 Query: 79 ESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPES-PRCQPKPSEEAPKCSQDQGVLASE 137 +P+ + + P R+Q H +Q + +P P+ P P ++ P Q + Sbjct: 721 MAPKSKKK---GHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQ----QQ 773 Query: 138 LAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEP-------------SQPLL----- 179 P PQ P + SP P+ Q P EP +QP+L Sbjct: 774 QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQP 833 Query: 180 ELTPRAPGSPRGQHEPSKPP 199 EL P P P E S PP Sbjct: 834 ELPPHLPQPP----EHSTPP 849 Score = 35.0 bits (79), Expect = 0.10 Identities = 36/101 (35%), Positives = 40/101 (39%), Gaps = 9/101 (8%) Query: 106 QPEYSPESPRCQPKPSEE--APKCSQDQGVLASELAQNKEELTPGAPQHQLP-PVPGSPE 162 + E S ES + SE APK S+ +G E Q K Q P PVP P Sbjct: 702 ESESSSESSSSDSEDSETEMAPK-SKKKGHPGRE--QKKHHHHHHQQMQQAPAPVPQQPP 758 Query: 163 PYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEP---SKPPP 200 P P Q P P P Q P P S Q P S PPP Sbjct: 759 PPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPP 799 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 60.5 bits (145), Expect = 2e-09 Identities = 86/321 (26%), Positives = 119/321 (37%), Gaps = 61/321 (19%) Query: 48 PPSVQRAGLGSPE---RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQ 104 PP+ L +P+ PP S SP A L P P A P H P Sbjct: 377 PPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANL------PPPPALKPLSSLSTH-HPPS 428 Query: 105 RQPEYSPESPRCQPKPSEEA--PKCSQDQGVL---ASELAQNKEELTPGAPQHQLPPVPG 159 P P+ QP PS A P +Q Q + AS ++ P P Q P VPG Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 488 Query: 160 SPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSS 219 P P P+ P P PG+ ++PP +G +GG A GSS Sbjct: 489 GPPPIT-------PPTCPSTSTPPAGPGTS------AQPPCSGAAASGGSIAG---GSSC 532 Query: 220 QAPA----SKKLNKEELPVIPKGKPKS-----------------GRVWK--DRSKKRFSQ 256 P + L+ E P P P+S R +K DR ++ Sbjct: 533 PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCAR 592 Query: 257 M-LQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERK 315 L PL S K +E K ++ + EE+ER ++++K+R +R E ER+ Sbjct: 593 TDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKER-----ERERERERE 647 Query: 316 AEVVQVIRNPAKLKRAKKKQL 336 AE + A R QL Sbjct: 648 AERAAKASSSAHEGRLSDPQL 668 Score = 48.9 bits (115), Expect = 7e-06 Identities = 58/218 (26%), Positives = 76/218 (34%), Gaps = 39/218 (17%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLES-----PQGQPEPGAA 90 +S+ ++ PP++Q A G P PG+P+L S PQG P A Sbjct: 172 DSSAQQQMLQAQPPALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA 230 Query: 91 SPQRQQDL------HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEE 144 Q Q H++ P SP P PS P L Q Sbjct: 231 PNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP-----LTGSAGQ---- 281 Query: 145 LTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA--G 202 P AP H PP+ G P P GP P P P G PP A G Sbjct: 282 --PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP-------GPPQPFG-----LPPQASQG 327 Query: 203 ETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 + G A +S Q PAS+ + + P P+ +P Sbjct: 328 QAPLGTSPAAAYPHTSLQLPASQSALQSQQP--PREQP 363 Score = 30.4 bits (67), Expect = 2.6 Identities = 50/242 (20%), Positives = 87/242 (35%), Gaps = 32/242 (13%) Query: 7 RSRRLGGLRPESPESLTSVSRTRRALVEFESNP--EETREPG--SPPSVQRAGLGSPERP 62 R+RR G S +L S + + A + ++P E+ R G SP + + S Sbjct: 19 RTRRSRG----SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAET 74 Query: 63 PKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSE 122 K S + + + L+S + Q E A+ + + + Q P SP S Sbjct: 75 VKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESS 134 Query: 123 EAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELT 182 ++ + + ++ Q+ +P P P + Q +L+ Sbjct: 135 DSRSVNDEGSSDPKDIDQDNRSTSPSIPS-----------PQDNESDSDSSAQQQMLQAQ 183 Query: 183 PRAPGSPRG-QHEPSKPPPA-------GETVTGGFGAKKRKGSSSQAPASKKLNKEELPV 234 P A +P G PS PP G T + + ++SQAP N+ + P Sbjct: 184 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-----NQPQAPT 238 Query: 235 IP 236 P Sbjct: 239 AP 240 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 60.5 bits (145), Expect = 2e-09 Identities = 86/321 (26%), Positives = 119/321 (37%), Gaps = 61/321 (19%) Query: 48 PPSVQRAGLGSPE---RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQ 104 PP+ L +P+ PP S SP A L P P A P H P Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANL------PPPPALKPLSSLSTH-HPPS 982 Query: 105 RQPEYSPESPRCQPKPSEEA--PKCSQDQGVL---ASELAQNKEELTPGAPQHQLPPVPG 159 P P+ QP PS A P +Q Q + AS ++ P P Q P VPG Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042 Query: 160 SPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSS 219 P P P+ P P PG+ ++PP +G +GG A GSS Sbjct: 1043 GPPPIT-------PPTCPSTSTPPAGPGTS------AQPPCSGAAASGGSIAG---GSSC 1086 Query: 220 QAPA----SKKLNKEELPVIPKGKPKS-----------------GRVWK--DRSKKRFSQ 256 P + L+ E P P P+S R +K DR ++ Sbjct: 1087 PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCAR 1146 Query: 257 M-LQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERK 315 L PL S K +E K ++ + EE+ER ++++K+R +R E ER+ Sbjct: 1147 TDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKER-----ERERERERE 1201 Query: 316 AEVVQVIRNPAKLKRAKKKQL 336 AE + A R QL Sbjct: 1202 AERAAKASSSAHEGRLSDPQL 1222 Score = 48.9 bits (115), Expect = 7e-06 Identities = 58/218 (26%), Positives = 76/218 (34%), Gaps = 39/218 (17%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLES-----PQGQPEPGAA 90 +S+ ++ PP++Q A G P PG+P+L S PQG P A Sbjct: 726 DSSAQQQMLQAQPPALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA 784 Query: 91 SPQRQQDL------HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEE 144 Q Q H++ P SP P PS P L Q Sbjct: 785 PNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP-----LTGSAGQ---- 835 Query: 145 LTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA--G 202 P AP H PP+ G P P GP P P P G PP A G Sbjct: 836 --PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP-------GPPQPFG-----LPPQASQG 881 Query: 203 ETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 + G A +S Q PAS+ + + P P+ +P Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQP--PREQP 917 Score = 30.4 bits (67), Expect = 2.6 Identities = 50/242 (20%), Positives = 87/242 (35%), Gaps = 32/242 (13%) Query: 7 RSRRLGGLRPESPESLTSVSRTRRALVEFESNP--EETREPG--SPPSVQRAGLGSPERP 62 R+RR G S +L S + + A + ++P E+ R G SP + + S Sbjct: 573 RTRRSRG----SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAET 628 Query: 63 PKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSE 122 K S + + + L+S + Q E A+ + + + Q P SP S Sbjct: 629 VKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESS 688 Query: 123 EAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELT 182 ++ + + ++ Q+ +P P P + Q +L+ Sbjct: 689 DSRSVNDEGSSDPKDIDQDNRSTSPSIPS-----------PQDNESDSDSSAQQQMLQAQ 737 Query: 183 PRAPGSPRG-QHEPSKPPPA-------GETVTGGFGAKKRKGSSSQAPASKKLNKEELPV 234 P A +P G PS PP G T + + ++SQAP N+ + P Sbjct: 738 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-----NQPQAPT 792 Query: 235 IP 236 P Sbjct: 793 AP 794 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 60.5 bits (145), Expect = 2e-09 Identities = 86/321 (26%), Positives = 119/321 (37%), Gaps = 61/321 (19%) Query: 48 PPSVQRAGLGSPE---RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQ 104 PP+ L +P+ PP S SP A L P P A P H P Sbjct: 931 PPTTPIPQLPAPQAHKHPPHLSGPSP-FSMNANL------PPPPALKPLSSLSTH-HPPS 982 Query: 105 RQPEYSPESPRCQPKPSEEA--PKCSQDQGVL---ASELAQNKEELTPGAPQHQLPPVPG 159 P P+ QP PS A P +Q Q + AS ++ P P Q P VPG Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042 Query: 160 SPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSS 219 P P P+ P P PG+ ++PP +G +GG A GSS Sbjct: 1043 GPPPIT-------PPTCPSTSTPPAGPGTS------AQPPCSGAAASGGSIAG---GSSC 1086 Query: 220 QAPA----SKKLNKEELPVIPKGKPKS-----------------GRVWK--DRSKKRFSQ 256 P + L+ E P P P+S R +K DR ++ Sbjct: 1087 PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCAR 1146 Query: 257 M-LQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERK 315 L PL S K +E K ++ + EE+ER ++++K+R +R E ER+ Sbjct: 1147 TDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKER-----ERERERERE 1201 Query: 316 AEVVQVIRNPAKLKRAKKKQL 336 AE + A R QL Sbjct: 1202 AERAAKASSSAHEGRLSDPQL 1222 Score = 48.9 bits (115), Expect = 7e-06 Identities = 58/218 (26%), Positives = 76/218 (34%), Gaps = 39/218 (17%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLES-----PQGQPEPGAA 90 +S+ ++ PP++Q A G P PG+P+L S PQG P A Sbjct: 726 DSSAQQQMLQAQPPALQ-APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQA 784 Query: 91 SPQRQQDL------HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEE 144 Q Q H++ P SP P PS P L Q Sbjct: 785 PNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQP-----LTGSAGQ---- 835 Query: 145 LTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA--G 202 P AP H PP+ G P P GP P P P G PP A G Sbjct: 836 --PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP-------GPPQPFG-----LPPQASQG 881 Query: 203 ETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 + G A +S Q PAS+ + + P P+ +P Sbjct: 882 QAPLGTSPAAAYPHTSLQLPASQSALQSQQP--PREQP 917 Score = 30.4 bits (67), Expect = 2.6 Identities = 50/242 (20%), Positives = 87/242 (35%), Gaps = 32/242 (13%) Query: 7 RSRRLGGLRPESPESLTSVSRTRRALVEFESNP--EETREPG--SPPSVQRAGLGSPERP 62 R+RR G S +L S + + A + ++P E+ R G SP + + S Sbjct: 573 RTRRSRG----SMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAET 628 Query: 63 PKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSE 122 K S + + + L+S + Q E A+ + + + Q P SP S Sbjct: 629 VKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESS 688 Query: 123 EAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELT 182 ++ + + ++ Q+ +P P P + Q +L+ Sbjct: 689 DSRSVNDEGSSDPKDIDQDNRSTSPSIPS-----------PQDNESDSDSSAQQQMLQAQ 737 Query: 183 PRAPGSPRG-QHEPSKPPPA-------GETVTGGFGAKKRKGSSSQAPASKKLNKEELPV 234 P A +P G PS PP G T + + ++SQAP N+ + P Sbjct: 738 PPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-----NQPQAPT 792 Query: 235 IP 236 P Sbjct: 793 AP 794 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 60.1 bits (144), Expect = 3e-09 Identities = 81/349 (23%), Positives = 140/349 (40%), Gaps = 45/349 (12%) Query: 20 ESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERP--PKTS---PGSPRLQQ 74 E S R+L + +S P R S + S RP P TS P SP Sbjct: 425 EKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSP 484 Query: 75 GAGLESPQGQPEPGA--ASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQG 132 G G P P P ASP+ + R+ E + ESP S P +D+ Sbjct: 485 GPGHTLPPKPPSPRGTTASPKGRV--------RRKEEAKESP------SAAGP---EDKS 527 Query: 133 VLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQ 192 + KE P +P P P +P P +Q P P+ + +P AP P Sbjct: 528 QSKRRASNEKESAAPASPAPSPAPSP-TPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTP 586 Query: 193 HEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKK 252 +P E T K+R+ A ++ +EE + R+ +R K+ Sbjct: 587 SKPMAGTTDREEATRLLAEKRRQ-------AREQREREE---------QERRLQAERDKR 630 Query: 253 -RFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKER--RRQEKKQRRAENLKRR 309 R Q+ ++ R + + + R+E++ A++ A+ +EE+ER +++E+ + R+ R Sbjct: 631 MREEQLAREAEARAEREAEARRREEQE-AREKAQAEQEEQERLQKQKEEAEARSREEAER 689 Query: 310 LENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAA 358 ER+ Q + + ++ ++ ++ K + QKQ ++ A Sbjct: 690 QRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANA 738 Score = 55.8 bits (133), Expect = 6e-08 Identities = 83/371 (22%), Positives = 134/371 (36%), Gaps = 73/371 (19%) Query: 39 PEETREPGSPPSVQRAGLGSPERP-----------PKTSPGSPRLQQGAGLESP-QGQPE 86 P+ T + P R+ SP P P G R G +P + +PE Sbjct: 349 PDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPE 408 Query: 87 PGAASPQRQQDLHLESPQRQPEYS-----------PESPRCQ---PKPSEEAPKCSQDQG 132 + ++D E+ + + + P SPR + SE +PK Sbjct: 409 ASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPS 468 Query: 133 VLASELAQNKEELTPGAPQHQLPPVPGSP---------------EPYPGQQAPGPEPSQP 177 ++ + P H LPP P SP E A GPE Sbjct: 469 SPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQ 528 Query: 178 LL-----ELTPRAPGSPRGQHEPSKPP-------PAGETVTGGFGAKKRKGSSSQAPASK 225 E AP SP PS P P ET T +S APA Sbjct: 529 SKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVL-----TSPPAPA-- 581 Query: 226 KLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFAR 285 P + KP +G ++ + +++L +K + QR+ +E QER+L + + Sbjct: 582 -------PPVTPSKPMAGTTDREEA----TRLLAEKRRQAREQREREE-QERRLQAERDK 629 Query: 286 HLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKK-QLRSIEKRDT 344 + EE+ R E + R +RR E E + + +L++ K++ + RS E+ + Sbjct: 630 RMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAER 689 Query: 345 LALLQKQPPQQ 355 L +++ QQ Sbjct: 690 QRLEREKHFQQ 700 Score = 53.1 bits (126), Expect = 4e-07 Identities = 58/239 (24%), Positives = 87/239 (36%), Gaps = 22/239 (9%) Query: 86 EPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEEL 145 E GA +P P+ PE P P P S P D +K Sbjct: 8 ELGAGAPPAVVARTPPEPRPSPEGDPSPP--PPPMSALVPDTPPDTPPAMKNATSSK--- 62 Query: 146 TPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPG----SPRGQHEPSKPPPA 201 QLP P SP G + P+ P E R P PR P + Sbjct: 63 -------QLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQP 115 Query: 202 GETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDK 261 T + K +A KL KE K VW ++ +K ++ L++K Sbjct: 116 SPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEK--AKALREK 173 Query: 262 PLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQ 320 L Q + + +E++L + R EE++R++ EK + R E +R + AE+ Q Sbjct: 174 QL----QERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQ 228 Score = 48.5 bits (114), Expect = 9e-06 Identities = 52/226 (23%), Positives = 93/226 (41%), Gaps = 36/226 (15%) Query: 142 KEELTPGAPQHQLPPVPGSPEPYP-GQQAPGPEPSQPLLELT-----------------P 183 + EL GAP + P P P P G +P P P L+ T P Sbjct: 6 RAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLP 65 Query: 184 RAPGSPRGQHEPSKPPPAGETVTGGFGAK-----------KRKGSSSQAPASKKLNKEEL 232 P SP GQ P PP E+ + ++ R S P+ + + Sbjct: 66 LEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDS 125 Query: 233 PVIPKGKPKSG---RVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEE 289 P + K+G ++ K+R ++R + K + + K K +E++L ++ R LEE Sbjct: 126 PPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQL-QERRRRLEE 184 Query: 290 EK---ERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAK 332 ++ E+RR ++R+ + L++ E A V + A++++ + Sbjct: 185 QRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQR 230 Score = 41.2 bits (95), Expect = 0.001 Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 15/126 (11%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGL----ESPQGQPEPGAAS 91 E P +P PP A + P+ PP T P L ESP GQ P A Sbjct: 24 EPRPSPEGDPSPPPPPMSALV--PDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAP 81 Query: 92 PQRQQDLHLESPQRQPE-YSPESPRCQPKPSEEAPKCSQDQ--GVLASELAQNKEELTPG 148 PQ ESP + + P P P+ + + SQ V AS+ K+E+ Sbjct: 82 PQE------ESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKA 135 Query: 149 APQHQL 154 +H+L Sbjct: 136 GERHKL 141 >gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sapiens] Length = 858 Score = 59.7 bits (143), Expect = 4e-09 Identities = 72/263 (27%), Positives = 104/263 (39%), Gaps = 66/263 (25%) Query: 125 PKCSQDQGVLASELAQNKEELTPGAPQHQLP----PVPGSPEPYPGQQAPGPEPSQPLLE 180 PK D VL + A K+ Q QLP P P P+P P PGP P P Sbjct: 158 PKDLDDLEVLVKQEAAGKQ-------QQQLPQTLQPQPPQPQPDPPPVPPGPTP-VPTGL 209 Query: 181 LTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 L P GS E A + + GF + +G SS + +EE P+ Sbjct: 210 LEPEPGGS-----EDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPE--- 261 Query: 241 KSGRVW--KDRSKKRFSQMLQDK--PLRTSWQRKMK------------------------ 272 +SG W ++++K+ F ++L+DK P SW++ MK Sbjct: 262 RSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAY 321 Query: 273 -------ERQERKL----AKDFARHLEEEKERRRQEKKQRRAENLKRRL-------ENER 314 E++E +L AK +H E+ ER + RRAE L E +R Sbjct: 322 KAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDR 381 Query: 315 KAEVVQVIRNPAKLKRAKKKQLR 337 K V+ AK ++ + KQLR Sbjct: 382 KEVYDDVLFFLAKKEKEQAKQLR 404 >gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sapiens] Length = 871 Score = 59.7 bits (143), Expect = 4e-09 Identities = 72/263 (27%), Positives = 104/263 (39%), Gaps = 66/263 (25%) Query: 125 PKCSQDQGVLASELAQNKEELTPGAPQHQLP----PVPGSPEPYPGQQAPGPEPSQPLLE 180 PK D VL + A K+ Q QLP P P P+P P PGP P P Sbjct: 164 PKDLDDLEVLVKQEAAGKQ-------QQQLPQTLQPQPPQPQPDPPPVPPGPTP-VPTGL 215 Query: 181 LTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 L P GS E A + + GF + +G SS + +EE P+ Sbjct: 216 LEPEPGGS-----EDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPE--- 267 Query: 241 KSGRVW--KDRSKKRFSQMLQDK--PLRTSWQRKMK------------------------ 272 +SG W ++++K+ F ++L+DK P SW++ MK Sbjct: 268 RSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAY 327 Query: 273 -------ERQERKL----AKDFARHLEEEKERRRQEKKQRRAENLKRRL-------ENER 314 E++E +L AK +H E+ ER + RRAE L E +R Sbjct: 328 KAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDR 387 Query: 315 KAEVVQVIRNPAKLKRAKKKQLR 337 K V+ AK ++ + KQLR Sbjct: 388 KEVYDDVLFFLAKKEKEQAKQLR 410 >gi|21328446 hormone-sensitive lipase [Homo sapiens] Length = 1076 Score = 58.5 bits (140), Expect = 9e-09 Identities = 57/222 (25%), Positives = 88/222 (39%), Gaps = 18/222 (8%) Query: 39 PEETREPGSP--PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGA---ASPQ 93 PE + P +P P ++ + PE KT GS Q+ A + P Q E A A Q Sbjct: 15 PEPHQRPITPLEPGPEKTPIAQPES--KTLQGSNTQQKPASNQRPLTQQETPAQHDAESQ 72 Query: 94 RQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAP--- 150 ++ +S ++ +P+ P Q P + +Q + KE +T P Sbjct: 73 KEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALR 132 Query: 151 -QHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGF 209 +H P PG EP P QQ P+ R P +P P + + T Sbjct: 133 QRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSDKQTTPVQ 192 Query: 210 GAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSK 251 GAK ++GS ++ KL +EL + +S WK S+ Sbjct: 193 GAKSKQGSLTELGFLTKL--QELSI-----QRSALEWKALSE 227 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 58.2 bits (139), Expect = 1e-08 Identities = 61/215 (28%), Positives = 76/215 (35%), Gaps = 32/215 (14%) Query: 39 PEETREPGSPPSVQRAGLGSPERPPKTSP---GSPRLQQGAGLESPQGQPEP-----GAA 90 P + GS P + S RP ++SP GSP + G SP P P G A Sbjct: 170 PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229 Query: 91 ---SPQRQQDLHLESP-QRQPEYSPESPRC-QPKPSEEAPKCSQDQGVLASELAQNKEEL 145 RQ L SP +P P R KP P + ++E + Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI-------HREAV 282 Query: 146 TPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETV 205 P PQ+ PPVP +P P QAP P P P PG P P P +G Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPP-------PPSRPGPP-----PLPPSSSGNDE 330 Query: 206 TGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 T + SSS P LP P +P Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365 Score = 52.8 bits (125), Expect = 5e-07 Identities = 63/245 (25%), Positives = 83/245 (33%), Gaps = 45/245 (18%) Query: 37 SNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQ 96 S+P R P PP+ RA P PP P + + A P +P S R Sbjct: 243 SSPFSNRPP-LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR-- 299 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPP 156 P S ++P P PS P L + N E TP PQ L Sbjct: 300 ----------PSASSQAPPPPPPPSRPGPP------PLPPSSSGNDE--TPRLPQRNLSL 341 Query: 157 VPGSPE-PYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRK 215 +P P PG+ P P P E P P G+ P PPP R Sbjct: 342 SSSTPPLPSPGRSGPLPPPPS---ERPPPPVRDPPGRSGPLPPPP----------PVSRN 388 Query: 216 GSSSQA-PASKKLNKEE---------LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRT 265 GS+S+A PA+ +L P +P +P +G QD P Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448 Query: 266 SWQRK 270 W+ + Sbjct: 449 EWESR 453 Score = 32.3 bits (72), Expect = 0.68 Identities = 36/159 (22%), Positives = 57/159 (35%), Gaps = 8/159 (5%) Query: 47 SPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQ 106 S P + G P PP + P ++ G P P P + + + L +PQ Sbjct: 344 STPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP-ATPQLP 402 Query: 107 PEYSPESPRCQPKP--SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQ----LPPVPGS 160 +SPR P+P + P S +N + +P + + P+ Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDL 462 Query: 161 PEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 P P P Q PS+ L R+ + R + P PP Sbjct: 463 PPPEPYVQTTKSYPSK-LARNESRSGSNRRERGAPPLPP 500 Score = 30.0 bits (66), Expect = 3.4 Identities = 35/145 (24%), Positives = 49/145 (33%), Gaps = 24/145 (16%) Query: 36 ESNPEETREPGS-------PPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEP- 87 E P R+P PP V R G S + P +P+L +G++SP+ P P Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTS-----RALPATPQLPSRSGVDSPRSGPRPP 417 Query: 88 --------GAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCS---QDQGVLAS 136 GA P Q P R P + P Q S Sbjct: 418 LPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477 Query: 137 ELAQNKEELTPGAPQHQLPPVPGSP 161 +LA+N+ + PP+P P Sbjct: 478 KLARNESRSGSNRRERGAPPLPPIP 502 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 58.2 bits (139), Expect = 1e-08 Identities = 61/215 (28%), Positives = 76/215 (35%), Gaps = 32/215 (14%) Query: 39 PEETREPGSPPSVQRAGLGSPERPPKTSP---GSPRLQQGAGLESPQGQPEP-----GAA 90 P + GS P + S RP ++SP GSP + G SP P P G A Sbjct: 170 PPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTA 229 Query: 91 ---SPQRQQDLHLESP-QRQPEYSPESPRC-QPKPSEEAPKCSQDQGVLASELAQNKEEL 145 RQ L SP +P P R KP P + ++E + Sbjct: 230 LGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI-------HREAV 282 Query: 146 TPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETV 205 P PQ+ PPVP +P P QAP P P P PG P P P +G Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPP-------PPSRPGPP-----PLPPSSSGNDE 330 Query: 206 TGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 T + SSS P LP P +P Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP 365 Score = 52.8 bits (125), Expect = 5e-07 Identities = 63/245 (25%), Positives = 83/245 (33%), Gaps = 45/245 (18%) Query: 37 SNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQ 96 S+P R P PP+ RA P PP P + + A P +P S R Sbjct: 243 SSPFSNRPP-LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPR-- 299 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPP 156 P S ++P P PS P L + N E TP PQ L Sbjct: 300 ----------PSASSQAPPPPPPPSRPGPP------PLPPSSSGNDE--TPRLPQRNLSL 341 Query: 157 VPGSPE-PYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRK 215 +P P PG+ P P P E P P G+ P PPP R Sbjct: 342 SSSTPPLPSPGRSGPLPPPPS---ERPPPPVRDPPGRSGPLPPPP----------PVSRN 388 Query: 216 GSSSQA-PASKKLNKEE---------LPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRT 265 GS+S+A PA+ +L P +P +P +G QD P Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448 Query: 266 SWQRK 270 W+ + Sbjct: 449 EWESR 453 Score = 32.3 bits (72), Expect = 0.68 Identities = 36/159 (22%), Positives = 57/159 (35%), Gaps = 8/159 (5%) Query: 47 SPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQ 106 S P + G P PP + P ++ G P P P + + + L +PQ Sbjct: 344 STPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP-ATPQLP 402 Query: 107 PEYSPESPRCQPKP--SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQ----LPPVPGS 160 +SPR P+P + P S +N + +P + + P+ Sbjct: 403 SRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDL 462 Query: 161 PEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 P P P Q PS+ L R+ + R + P PP Sbjct: 463 PPPEPYVQTTKSYPSK-LARNESRSGSNRRERGAPPLPP 500 Score = 30.0 bits (66), Expect = 3.4 Identities = 35/145 (24%), Positives = 49/145 (33%), Gaps = 24/145 (16%) Query: 36 ESNPEETREPGS-------PPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEP- 87 E P R+P PP V R G S + P +P+L +G++SP+ P P Sbjct: 363 ERPPPPVRDPPGRSGPLPPPPPVSRNGSTS-----RALPATPQLPSRSGVDSPRSGPRPP 417 Query: 88 --------GAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCS---QDQGVLAS 136 GA P Q P R P + P Q S Sbjct: 418 LPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477 Query: 137 ELAQNKEELTPGAPQHQLPPVPGSP 161 +LA+N+ + PP+P P Sbjct: 478 KLARNESRSGSNRRERGAPPLPPIP 502 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 57.8 bits (138), Expect = 2e-08 Identities = 75/274 (27%), Positives = 101/274 (36%), Gaps = 61/274 (22%) Query: 22 LTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPER-----PPKTSPGSPR----- 71 L VSR E +P P SPP PE PP+ SP SP Sbjct: 656 LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSL 715 Query: 72 ----LQQGAGLESPQGQPE--PGAASPQ---RQQDLHLESPQRQPEYSP--ESPRCQPKP 120 L++ L P+ +P+ P + P R ++ HL +P SP E P P+P Sbjct: 716 MSLPLEESPLLPLPE-EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774 Query: 121 SE-------EAPKCS-QDQGVLASELAQNKEE--LTPGAPQHQLPPVPGSP--EPYPGQQ 168 E E P S Q +G L+ EE L+P + L PVP P P P + Sbjct: 775 EEPCLCAVPEEPHLSPQAEG---PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEES 831 Query: 169 APGPEPSQPLLELTP----------RAPGSPRGQHEPSKP------------PPAGETVT 206 P+ +P L P + P SPR + P +P PP GE Sbjct: 832 HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSL 891 Query: 207 GGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 + + P S EELP+ P G+P Sbjct: 892 SPLLGEPALSEPGEPPLSPL--PEELPLSPSGEP 923 Score = 48.5 bits (114), Expect = 9e-06 Identities = 57/181 (31%), Positives = 70/181 (38%), Gaps = 22/181 (12%) Query: 39 PEETREPGSPPSVQRAGLGSPER-----PPKTSPGSP---RLQQGAGLE----SPQGQPE 86 PEE+ P SPP + PE PP+ P SP L LE SP + Sbjct: 444 PEES--PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEES 501 Query: 87 PGAASPQRQQDLHLE-SPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEEL 145 P + P+ LE SP PE SP SP + S S L+ EEL Sbjct: 502 PLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561 Query: 146 T----PGAPQHQLPPV--PGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 P A + PP P SP P +P PE S+ L +P SP + P PP Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR-LFPPFEESPLSPPPEESPLSPP 620 Query: 200 P 200 P Sbjct: 621 P 621 Score = 47.8 bits (112), Expect = 2e-05 Identities = 52/189 (27%), Positives = 68/189 (35%), Gaps = 36/189 (19%) Query: 44 EPGSPPSVQRAGLGSPERPPKTSPGSPRLQ-QGAGLESPQGQPEPGAASPQRQQDLHLES 102 +P P V ++G G P + G R Q QG ++PQ + SPQ+QQ L Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRH----LSPQQQQQLQALL 4226 Query: 103 PQRQPEYSP--------ESPRCQPKPSEEAPKCSQDQGVLASELAQNKEEL--------- 145 QRQ + S + P Q P + C G +EL Sbjct: 4227 MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGP 4286 Query: 146 -----TPGA--------PQHQLPPVPGSPEPYPGQQAPGPEPSQPL-LELTPRAPGSPRG 191 PGA P H PP EP Q P P P +L P PG+P+ Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKP 4346 Query: 192 QHEPSKPPP 200 Q +PPP Sbjct: 4347 QGPTLEPPP 4355 Score = 46.6 bits (109), Expect = 3e-05 Identities = 54/207 (26%), Positives = 77/207 (37%), Gaps = 37/207 (17%) Query: 62 PPKTSPGSPRLQQGAGLESPQGQ-----PEPGAASPQRQQDLHLESPQRQPEYSPESPRC 116 PP+ SP SP ++ P+ PE ASP + LHL P E SP SP Sbjct: 443 PPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA-LHLSRPL---EESPLSP-- 496 Query: 117 QPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQ 176 P EE+P L+P P+ SP P + P P Sbjct: 497 ---PPEESP-------------------LSPPPESSPFSPLEESPLSPPEESPPSPALET 534 Query: 177 PLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIP 236 PL +P SP + P PPP + A + ++P S EE P+ P Sbjct: 535 PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP--PEESPMSP 592 Query: 237 KGKPKSGRVWKDRSKKRFSQMLQDKPL 263 P++ R++ + S ++ PL Sbjct: 593 --PPEASRLFPPFEESPLSPPPEESPL 617 Score = 41.2 bits (95), Expect = 0.001 Identities = 44/167 (26%), Positives = 59/167 (35%), Gaps = 13/167 (7%) Query: 37 SNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQ 96 S P E PP E P P RL + PE SP + Sbjct: 618 SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPE- 676 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPP 156 ESP P PE+ R P P E++P + AS ++ P + L P Sbjct: 677 ----ESPTSPP---PEASRLSP-PPEDSPTSPPPEDSPASPPPEDSLMSLP-LEESPLLP 727 Query: 157 VPGSPEPYPGQQAP--GPEPSQPLLELTPRAPG-SPRGQHEPSKPPP 200 +P P+ P + P P P +P L P P SP+ + P P Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774 Score = 40.0 bits (92), Expect = 0.003 Identities = 53/191 (27%), Positives = 68/191 (35%), Gaps = 47/191 (24%) Query: 16 PESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSP------ERPPKTSPGS 69 P SP SR E +P P SPP + + L P PP+ SP S Sbjct: 562 PTSPPP--EASRLSPPPEESPMSPPPEESPMSPPP-EASRLFPPFEESPLSPPPEESPLS 618 Query: 70 PRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQ 129 P + A SP + P + P+ ESP P PE R P P Sbjct: 619 PPPE--ASRLSPPPEDSPMSPPPE-------ESPMSPP---PEVSRLSPLP--------- 657 Query: 130 DQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSP 189 + S L+ EE P + P SP P + +P PE S P SP Sbjct: 658 ----VVSRLSPPPEESPLSPPPEESPT---SPPPEASRLSPPPEDS----------PTSP 700 Query: 190 RGQHEPSKPPP 200 + P+ PPP Sbjct: 701 PPEDSPASPPP 711 Score = 39.3 bits (90), Expect = 0.006 Identities = 64/248 (25%), Positives = 84/248 (33%), Gaps = 66/248 (26%) Query: 11 LGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSP 70 LGGL ++P+ + R + VE +S P P PP Q P P PGS Sbjct: 2316 LGGLELKTPDVFKAPLTPRASQVEPQS-PGLGLRPQEPPPAQALAPSPPSHPDIFRPGS- 2373 Query: 71 RLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQD 130 P QP P +PR QP P E C+ Sbjct: 2374 -------YTDPYAQP-------------------------PLTPRPQPPPPESC--CALP 2399 Query: 131 QGVLASELAQNKEELTPGAPQHQ------LPPVPGSPEPY------PGQQAPGPEPSQPL 178 L S+ P +PQ Q L P P S E + P Q+P P S+P Sbjct: 2400 PRSLPSDPFSR----VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPY-SRPP 2454 Query: 179 LELTPRAPGSPRGQHEPSKPPP------AGETVTGGFGAKKRKGSSSQAPASKKLNKEEL 232 R P +P H+P +P P AG GA + PA + K Sbjct: 2455 SRPQSRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAK--- 2509 Query: 233 PVIPKGKP 240 +P G+P Sbjct: 2510 --VPSGQP 2515 Score = 37.4 bits (85), Expect = 0.021 Identities = 48/173 (27%), Positives = 61/173 (35%), Gaps = 56/173 (32%) Query: 48 PPSVQRAGLGSPERPPKTSP----GSPRLQQGAGLESPQGQPEPGAAS---PQRQQDLHL 100 PP Q LGSP PP +P GSP G S G +P A S P +L L Sbjct: 2107 PP--QPGALGSP--PPAAAPTIFIGSPTTPAGLST-SADGFLKPPAGSVPGPDSPGELFL 2161 Query: 101 ESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGS 160 + P + P P +Q+ L P P P P + Sbjct: 2162 KLPPQVPAQVP---------------------------SQDPFGLAPAYPLE--PRFPTA 2192 Query: 161 PEPYPGQQAPGPEPSQPLL-------------ELTPRAPGSPRGQHEPSKPPP 200 P YP +P P+QP + E PG+PR H+PS P P Sbjct: 2193 PPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPR--HQPSTPDP 2243 Score = 36.2 bits (82), Expect = 0.047 Identities = 45/197 (22%), Positives = 75/197 (38%), Gaps = 36/197 (18%) Query: 77 GLESPQGQPEPG-----AASPQRQQDLHLESPQRQP----EYSPESPR-------CQPKP 120 G+++P QPEPG AS + + L+ + P E PE + C+ + Sbjct: 1127 GIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQE 1186 Query: 121 SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLP---PVPGSPEPYPGQQAPGPEPSQP 177 AP ++ S++ L+ G P P+ GSP+P G S Sbjct: 1187 EPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSL-----SME 1241 Query: 178 LLELTPRAPGSPRG----------QHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKL 227 L T +P G + + S AG ++GG A+ KG +PA ++ Sbjct: 1242 LGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGG-KAEGEKGRRRSSPARSRI 1300 Query: 228 NKEELPVIP-KGKPKSG 243 + P + +P+ G Sbjct: 1301 KQGRSSSFPGRRRPRGG 1317 Score = 35.8 bits (81), Expect = 0.061 Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 37 SNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAA 90 S+P+E + P PS + L + + P T PG+P+ QG LE P G+ P AA Sbjct: 4312 SSPQEPKRPSQLPSPS-SQLPTEAQLPPTHPGTPK-PQGPTLEPPPGRVSPAAA 4363 Score = 34.7 bits (78), Expect = 0.14 Identities = 40/158 (25%), Positives = 50/158 (31%), Gaps = 21/158 (13%) Query: 45 PGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQ 104 PGS PS R P P + + R G Q P PG+ Q+QQ + Q Sbjct: 2763 PGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQ 2822 Query: 105 RQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPY 164 S PS P+ + L S LA L P Sbjct: 2823 ATAATSMRFAMSARFPSTPGPELGRQ--ALGSPLAGISTRL-----------------PG 2863 Query: 165 PGQQAPGPEPSQPLLELTPRAPG--SPRGQHEPSKPPP 200 PG+ PGP +EL P G P + PP Sbjct: 2864 PGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPP 2901 Score = 32.7 bits (73), Expect = 0.52 Identities = 43/156 (27%), Positives = 57/156 (36%), Gaps = 20/156 (12%) Query: 63 PKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSE 122 P T G P L G ES EPG P D L Q QP+ P S + QP P Sbjct: 4041 PSTHQGGP-LAIGTTPESMA--TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQP-PLR 4096 Query: 123 EAPKCSQDQGVLASELAQNKEELTPGAPQH--QLPPVPGSPEPYPGQQAPGP------EP 174 + Q +L + + +L G+ +P + P G Q PG P Sbjct: 4097 LPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQ-PGSMTQNLLGP 4155 Query: 175 SQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFG 210 QP+LE P + +PP G + G G Sbjct: 4156 QQPMLE-------RPMQNNTGPQPPKPGPVLQSGQG 4184 Score = 31.6 bits (70), Expect = 1.2 Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 11/111 (9%) Query: 155 PPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKK- 213 PP SP P P +P P++PL+EL P P + P P + + Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVEL----PTEPLAEPPVPSPLPLASSPESARPKPRA 4965 Query: 214 ---RKGSSSQAPASKK---LNKEELPVIPKGKPKSGRVWKDRSKKRFSQML 258 +G S+ P KK + + L ++ + SGR +R F + L Sbjct: 4966 RPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQL 5016 Score = 29.6 bits (65), Expect = 4.4 Identities = 67/291 (23%), Positives = 107/291 (36%), Gaps = 48/291 (16%) Query: 55 GLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESP 114 GLG+P+ K GS R + S +G P A ++ LE P Sbjct: 1800 GLGTPKA--KGDGGSERKELPT---SQKGDDGPDIAD---EESRGLEGKADTPGPEDGGV 1851 Query: 115 RCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAP----QHQLPPVPGSP-EPYPGQQA 169 + P PS+ + +G+L+S+L + E P Q V GS E + G Sbjct: 1852 KASPVPSDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLGCGT 1911 Query: 170 PGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA--GETVTGGFGAKKRKGSSSQAPASKKL 227 PG E S+ L+ G P G S P + G + +++R G S P Sbjct: 1912 PGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDS 1971 Query: 228 -------NKEELPVIPKGKPK-SGRVWKDRSKKR----------------------FSQM 257 P P + + G + RS +R F + Sbjct: 1972 PWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNL 2031 Query: 258 LQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERR---RQEKKQRRAEN 305 QD P +S +++ + + A D A +L++ K+ R R K Q++AE+ Sbjct: 2032 KQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAES 2082 Score = 29.6 bits (65), Expect = 4.4 Identities = 46/207 (22%), Positives = 83/207 (40%), Gaps = 16/207 (7%) Query: 21 SLTSVSRTRRALVEFESNPEETREP-GSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLE 79 S+ +S +++L+ P+ + +P GS +Q+ ++ + +LQQ L+ Sbjct: 3869 SMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQ-QQQLQQQQQLQ 3927 Query: 80 SPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELA 139 Q Q Q+QQ L+ Q+Q + Q + ++ Q Q L Sbjct: 3928 QQQLQ--------QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLN 3979 Query: 140 QNKEELTPGAPQHQLPPV-PGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKP 198 Q++ L+P Q Q + PG P P Q P P L LT G + +P+ Sbjct: 3980 QSRTLLSPQQQQQQQVALGPGMPAK-PLQHFSSPGALGPTLLLT----GKEQNTVDPAVS 4034 Query: 199 PPAGETVTGGFGAKKRKGSSSQAPASK 225 A E + G G++ ++ A++ Sbjct: 4035 SEATEGPSTHQGGPLAIGTTPESMATE 4061 Score = 29.3 bits (64), Expect = 5.7 Identities = 48/165 (29%), Positives = 58/165 (35%), Gaps = 49/165 (29%) Query: 43 REPGSP-PSVQRAGLGSPERPPKT---SPGSP---------------RLQQGAGLESPQG 83 R P +P P + R LGSP T PG P +Q+G G P G Sbjct: 2836 RFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLG---PGG 2892 Query: 84 QPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKE 143 P PG PQR P + P S P AP+ +G+ S L K Sbjct: 2893 TPFPGQGPPQR------------PRFYPVS----EDPHRLAPEGL--RGLAVSGLPPQK- 2933 Query: 144 ELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGS 188 P AP P + S P P + P LEL R P S Sbjct: 2934 ---PSAP--PAPELNNSLHPTPHTKGPTLPTG---LELVNRPPSS 2970 >gi|110431370 espin [Homo sapiens] Length = 854 Score = 57.4 bits (137), Expect = 2e-08 Identities = 91/336 (27%), Positives = 129/336 (38%), Gaps = 59/336 (17%) Query: 26 SRTRRALVEFESNPEETREPGSPPS---VQRAGLGSPERPPKTSP---GSPRLQQGA--G 77 SR RA + S + R+ G P R G+ E P G PRL A Sbjct: 504 SRKPRAFSKQPSTGDYYRQLGRCPGETLAARPGMAHSEEVRARQPARAGCPRLGPAARGS 563 Query: 78 LESPQGQPE----PG-------AASPQRQQDLHLESPQRQP---EYSPESPRCQPKPSEE 123 LE P P+ PG AA P+ ++L P P E + P P P E Sbjct: 564 LEGPSAPPQAALLPGNHVPNGCAADPKASRELPPPPPPPPPPLPEAASSPPPAPPLPLES 623 Query: 124 A-PKCSQDQGV----------LASELAQNKEELTPGAPQHQLPPVP---GSPEPYPGQQA 169 A P C Q + + S N E L L P P G + G Sbjct: 624 AGPGCGQRRSSSSTGSTKSFNMMSPTGDNSELLAEIKAGKSLKPTPQSKGLTTVFSGIGQ 683 Query: 170 PGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNK 229 P +P PL ++P SP S PPA GF GS P + Sbjct: 684 PAFQPDSPLPSVSPAL--SP----VRSPTPPAA-----GF-QPLLNGSLVPVPPTTPAPG 731 Query: 230 EELPV---IPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLA------ 280 +L V IP + GR + ++ + +Q K QR+ +E +E +LA Sbjct: 732 VQLDVEALIPT-HDEQGRPIPEWKRQVMVRKMQLKMQEEEEQRRKEEEEEARLASMPAWR 790 Query: 281 KDFARH-LEEEKERRRQEKKQRRAENLKRRLENERK 315 +D R LEEE+E++R+E+++++ E L+R E K Sbjct: 791 RDLLRKKLEEEREQKRKEEERQKQEELRREKEQSEK 826 Score = 30.8 bits (68), Expect = 2.0 Identities = 37/162 (22%), Positives = 54/162 (33%), Gaps = 18/162 (11%) Query: 72 LQQGAGLESPQGQPEPGAASPQ-----RQQDLHLESPQRQPEYSPESPRCQPKPSEEAPK 126 L + E QP+ G +SP + + L SP + P Sbjct: 337 LSRDPSAELEAKQPDSGMSSPNTTVSVQPLNFDLSSPTSTLSNYDSCSSSHSSIKGQHPP 396 Query: 127 CSQDQGVLASELAQNKEELTP--GAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPR 184 C A+++ + L P G P+ + G P P P + P P P +L P Sbjct: 397 CGLSSA-RAADIQSYMDMLNPELGLPRGTI----GKPTPPPPPPSFPPPPPPPGTQLPPP 451 Query: 185 APGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKK 226 PG P+ PP G + K K + A KK Sbjct: 452 PPG------YPAPKPPVGPQAADIYMQTKNKLRHVETEALKK 487 >gi|151301053 RNA binding motif protein 33 [Homo sapiens] Length = 1170 Score = 56.2 bits (134), Expect = 4e-08 Identities = 72/301 (23%), Positives = 114/301 (37%), Gaps = 63/301 (20%) Query: 45 PGSP--PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQP----------------- 85 PG P P+ + L P PP P P+ QQ PQ QP Sbjct: 565 PGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQ 624 Query: 86 EPGAASPQRQQDLHLES---------PQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLAS 136 P PQ Q H P QP++ P QP+ S +C Q QG+ + Sbjct: 625 HPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHN 684 Query: 137 ELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEP- 195 +QN + P Q+ P +P ++ P PS + + R +P Q +P Sbjct: 685 TTSQNVSK----RPMQQMQPT--APRNSNLRELP-IAPSHVIEMSSSRCSATPSAQVKPI 737 Query: 196 -SKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRF 254 S PP+ V G SSQ K+ P P +P K+ +K Sbjct: 738 VSASPPS-RAVAG--------SRSSQGKTEVKVK----PASPVAQP------KEEAKTET 778 Query: 255 SQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENER 314 +D+ R ++K ++++L ++ + +KE RRQ++ R + L RL ++ Sbjct: 779 EFPDEDEETRL---YRLKIEEQKRLREEILK----QKELRRQQQAGARKKELLERLAQQQ 831 Query: 315 K 315 + Sbjct: 832 Q 832 Score = 42.7 bits (99), Expect = 5e-04 Identities = 60/254 (23%), Positives = 86/254 (33%), Gaps = 34/254 (13%) Query: 9 RRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERP------ 62 R +G R ES E + R AL+ + P PP Q+ + S +P Sbjct: 286 RGVGDQRRESTER-GRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPL 344 Query: 63 -PKTSPGSPRLQQGAG----LESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQ 117 P P P QG LE+P+ P +PQ+ +++H+ + +P Sbjct: 345 LPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLL 404 Query: 118 PKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGS---PEPYPGQ-QAPGPE 173 P PS+ P + + P PQH PVP S P P Q Q P Sbjct: 405 PVPSQPRP-----------AVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPP 453 Query: 174 PSQPLLELTPRAPGSPR-------GQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKK 226 P Q G PR Q P PPP + + P Sbjct: 454 PPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAF 513 Query: 227 LNKEELPVIPKGKP 240 + + PV P+ +P Sbjct: 514 NQQGQQPVFPRERP 527 Score = 29.6 bits (65), Expect = 4.4 Identities = 43/177 (24%), Positives = 70/177 (39%), Gaps = 28/177 (15%) Query: 63 PKTS---PGSPRLQ-QGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYS----PESP 114 PKTS P S +Q QG +++ + + + Q LH P + + P++P Sbjct: 888 PKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTP 947 Query: 115 RC---QPKPSEEAPKCSQ-----------DQGVLASELAQNKEELTPGAPQHQLPPVPGS 160 R Q +P + P + D ++S++ K G P G Sbjct: 948 RVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHP-EGQ 1006 Query: 161 PEPYPGQQAPGPEPSQPLLELT----PRAPGSPRGQHEPSKPPPAGETVTGGFGAKK 213 P+ P GP+P++ + LT + P P G H S PP +++ G AKK Sbjct: 1007 PQRLPQPPEVGPQPARKVT-LTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKK 1062 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 56.2 bits (134), Expect = 4e-08 Identities = 54/202 (26%), Positives = 74/202 (36%), Gaps = 16/202 (7%) Query: 14 LRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQ 73 LR ES+ ++ + L + E RE S + A PE P K P +P Sbjct: 415 LRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRRPPE-PEKAPPAAPTRP 473 Query: 74 QGAGLESPQGQPE--------PGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP----- 120 L+ + + + PG A + + +P +P P P P Sbjct: 474 SALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPA 533 Query: 121 SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLE 180 +E AP + L + +E P AP Q PP+PGSPEP P PG P P Sbjct: 534 AEPAPGAAPPPPPPLPGLP-SPQEAPPSAPP-QAPPLPGSPEPPPAPPLPGDLPPPPPPP 591 Query: 181 LTPRAPGSPRGQHEPSKPPPAG 202 P P P PPP G Sbjct: 592 PPPPGTDGPVPPPPPPPPPPPG 613 Score = 50.1 bits (118), Expect = 3e-06 Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 49/191 (25%) Query: 15 RPESPESLTSVSRTRRALVEFESNPEET-------REPGSPPSVQ--RAGLGSPERPPKT 65 RP PE + TR + +E + E R PG S++ + +P Sbjct: 458 RPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAP 517 Query: 66 SPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAP 125 +PG P L +P +P PGAA P L SPQ P +P P+ P P P Sbjct: 518 TPGVPTGSPSPDL-APAAEPAPGAAPPPPPPLPGLPSPQEAPPSAP--PQAPPLPGSPEP 574 Query: 126 KCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGS-------PEPYPGQQAPGPEPSQPL 178 P AP P+PG P P PG P P P P Sbjct: 575 ---------------------PPAP-----PLPGDLPPPPPPPPPPPGTDGPVPPPPPP- 607 Query: 179 LELTPRAPGSP 189 P PG P Sbjct: 608 ---PPPPPGGP 615 Score = 32.7 bits (73), Expect = 0.52 Identities = 23/66 (34%), Positives = 25/66 (37%), Gaps = 9/66 (13%) Query: 146 TPGAPQHQLPPVP-GSPEPY---PGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA 201 TP P VP GSP P + APG P P P PG P Q P PP Sbjct: 510 TPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPP-----PPLPGLPSPQEAPPSAPPQ 564 Query: 202 GETVTG 207 + G Sbjct: 565 APPLPG 570 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 55.8 bits (133), Expect = 6e-08 Identities = 62/236 (26%), Positives = 80/236 (33%), Gaps = 34/236 (14%) Query: 31 ALVEFESNPEETREP-------GSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQG 83 AL ES+ E+ + G P + G P+RPP PG P+ G QG Sbjct: 12 ALSSAESSSEDVSQEESLFLISGKPEGRRPQGGNQPQRPPPP-PGKPQGPPPQGGNQSQG 70 Query: 84 QPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKC-SQDQGVLASELAQNK 142 P P R P + S P KP P+ +Q QG + Sbjct: 71 PPPPPGKPEGR--------PPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPER 122 Query: 143 EELTPGAPQHQLPPVPGSPE---PYPGQQAPGPEPSQPLLELTP-----------RAPGS 188 G H+ PP PG PE P G Q+ GP P E P PG Sbjct: 123 PPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGK 182 Query: 189 PRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGR 244 P+G + P G G G + Q P + K + P P P+ GR Sbjct: 183 PQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPP---PQGGR 235 Score = 42.4 bits (98), Expect = 7e-04 Identities = 39/131 (29%), Positives = 43/131 (32%), Gaps = 6/131 (4%) Query: 45 PGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQP-EPGAASPQRQQDLHLESP 103 PG P G RPP PG P G QG P PG Q+ + Sbjct: 117 PGKPERPPPQGGNQSHRPPPP-PGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRS 175 Query: 104 QRQPEYSPESPRCQP--KPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGS- 160 R P P+ P Q KP P A Q + G PQ PP G Sbjct: 176 ARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGR 235 Query: 161 -PEPYPGQQAP 170 P P GQQ P Sbjct: 236 PPRPAQGQQPP 246 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 55.5 bits (132), Expect = 7e-08 Identities = 75/346 (21%), Positives = 138/346 (39%), Gaps = 51/346 (14%) Query: 43 REPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLES 102 R G PPS PERP S + L++ ++ + + G A Q + D Sbjct: 279 RGRGPPPS----WASEPERPSILS--ASELKELDKFDNLDAEADEGWAGAQMEVDY---- 328 Query: 103 PQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPE 162 Q +S + + P E S+DQG ASE +NK+E + +P P Sbjct: 329 -TEQLNFSDDDEQGSNSPKENN---SEDQGSKASENNENKKETDEVSNTKSSSQIPAQPS 384 Query: 163 PYPGQQAPGPEPSQP--LLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGA--------- 211 GP +Q P P QH PPP + V G G Sbjct: 385 VAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQH----PPPDRQAVPGRPGPFPSKQQVAD 440 Query: 212 -----KKRKGSSSQAPAS-----KKLNKEELPVIPKGKP-----------KSGRVWKDRS 250 K+R+ S+ A+ K+ +EE + + K K G + K S Sbjct: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500 Query: 251 KKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRL 310 + + ++K + + ++ QER+ ++ R ++EKE+ EK+Q + +++ Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKE-LEKEQEKQREMEKER 559 Query: 311 ENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQP 356 + E++ E+ + +L++ K+++ +++ L +K P++P Sbjct: 560 KQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREP 605 Score = 35.4 bits (80), Expect = 0.080 Identities = 80/374 (21%), Positives = 129/374 (34%), Gaps = 88/374 (23%) Query: 4 PLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEET--REPGSPPSVQRAGLGSPER 61 PL R ++ G P S ES ++R+ R S P +P Q+A Sbjct: 769 PLMRRDQMEG-SPNSSESFEHIARSARDHAISLSEPRMLWGSDPYPHAEPQQATTPKATE 827 Query: 62 PPKTSPGSPRLQQ-----GAGLESPQGQPEPGA------ASPQRQQDLHLESPQRQPEYS 110 P+ L Q +E Q + P A + Q Q+ L +P ++ Sbjct: 828 EPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESSEAQVQKFLSRSVEDVRPHHT 887 Query: 111 PESPR--CQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQ 168 + + C P ++ Q++ + A E +++ H P Sbjct: 888 DANNQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKP-----------D 936 Query: 169 APGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKG--SSSQAPASKK 226 EPS + ++T R S P + P K++G SS+ P +K Sbjct: 937 EQRSEPSAGIPKVTSRCIDSKEPIERPEEKP-------------KKEGFIRSSEGPKPEK 983 Query: 227 LNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARH 286 + K KS W R + + D+P+R S K K R Sbjct: 984 VYKS----------KSETRWGPRPSSNRREEVNDRPVRRSGPIK----------KPVLRD 1023 Query: 287 LEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLA 346 ++EE+E+R+ EK+ +AE + + V+ P K EK+D Sbjct: 1024 MKEEREQRK-EKEGEKAEKVTEK-----------VVVKPEK-----------TEKKD--- 1057 Query: 347 LLQKQPPQQPAAKI 360 L PP QP A I Sbjct: 1058 LPPPPPPPQPPAPI 1071 Score = 33.5 bits (75), Expect = 0.30 Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 6/127 (4%) Query: 41 ETREPGSPPSVQRA----GLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQ 96 E REP P V++ E P T S R ++ A + +PE G S R Sbjct: 601 EPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESG--SQPRPA 658 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPP 156 L Q Q P R Q + ++ + Q QGVL + T P H+ Sbjct: 659 VLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPSSSTVPPPPHRPLY 718 Query: 157 VPGSPEP 163 P P P Sbjct: 719 QPMQPHP 725 Score = 31.2 bits (69), Expect = 1.5 Identities = 45/214 (21%), Positives = 79/214 (36%), Gaps = 44/214 (20%) Query: 16 PESPESLTSVSRTRRALVEFESNPEETREPGS---PPSVQRAGLGSPERPPKTSPGSPRL 72 P P + ++T + + NP +T S PPS++ +P G+ + Sbjct: 1924 PAPPAPAQTQAQTHKPV----QNPLQTTSQSSKQPPPSIRLPSAQTPN-------GTDYV 1972 Query: 73 QQGAGLESPQG-----------QPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQP--- 118 G +++PQ + P A + L SP + P S + Sbjct: 1973 ASGKSIQTPQSHGTLTAELWDNKVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGS 2032 Query: 119 KPSEEAPKCSQDQGV-LASELAQ--------NKEELTPGAPQHQLPPVPGSPEPYPGQQA 169 PS E K Q+ G+ + ++ Q N+ E+ P + +P E Q Sbjct: 2033 APSSEGAKNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPR 2092 Query: 170 PGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGE 203 GP +Q L +L+P +++ KP P G+ Sbjct: 2093 AGPIKAQKLPDLSP-------VENKEHKPGPIGK 2119 Score = 29.6 bits (65), Expect = 4.4 Identities = 48/204 (23%), Positives = 72/204 (35%), Gaps = 32/204 (15%) Query: 85 PEPGAASPQRQQD--LHLESPQRQP---EYSPESPRCQPKPSEEAPKCSQDQGVLASELA 139 P P + + D + P ++P + E + + K E+A K ++ V+ Sbjct: 995 PRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTEK--VVVKPEK 1052 Query: 140 QNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGP-EPSQPLLELTPRAPGSPRGQHEPSKP 198 K++L P PP P P P Q P P +P T A + + + KP Sbjct: 1053 TEKKDLPPP------PPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQDTEKP 1106 Query: 199 PPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELP-----VIPKGKPKSGRVWKDRSKKR 253 TV K + AP K+ + E VI + +P S K S Sbjct: 1107 LEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKES--- 1163 Query: 254 FSQMLQDKPLRTSWQRKMKERQER 277 P RT W KE +ER Sbjct: 1164 ------TLPPRTYW----KEARER 1177 Score = 29.3 bits (64), Expect = 5.7 Identities = 39/177 (22%), Positives = 59/177 (33%), Gaps = 33/177 (18%) Query: 50 SVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEY 109 S+ + G+ PP P S + + + P+ G +Q+ Q + E Sbjct: 44 SLGKVGISRRMPPPANLP-SLKAENKGNDPNVNIVPKDGTGWASKQE-------QHEEEK 95 Query: 110 SPESPRCQPKPSEEAPK---------CSQDQGVLASELAQNKEELTPGAPQHQLPPVPGS 160 +PE P QPKP AP S QG + N + Q + P + + Sbjct: 96 TPEVPPAQPKPGVAAPPEVAPAPKSWASNKQGGQGDGIQVNSQF------QQEFPSLQAA 149 Query: 161 -------PEPYPGQQAPGPE---PSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTG 207 E PGP P+ +A GSP + K P E+ G Sbjct: 150 GDQEKKEKETNDDNYGPGPSLRPPNVACWRDGGKAAGSPSSSDQDEKLPGQDESTAG 206 >gi|54860079 nadrin isoform 1 [Homo sapiens] Length = 881 Score = 55.1 bits (131), Expect = 1e-07 Identities = 53/174 (30%), Positives = 68/174 (39%), Gaps = 20/174 (11%) Query: 44 EPGSPPSVQRAGL---GSPERPPKTSPGSPRLQQGAGLE---SPQGQPE-PGAASPQRQQ 96 +PG+PP G G+ + PP SP P + P GQP P S R+ Sbjct: 642 KPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRY 701 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQ---DQGVLASELAQNKEELTPGAPQHQ 153 L SP + P + P P Q P SQ + L SE + TP PQ Sbjct: 702 SSSL-SPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTP--PQTP 758 Query: 154 LPP-VPGSPEPYPGQQAP------GPEPSQPLLELTPRAPGSPRGQHEPSKPPP 200 PP P + P AP PE +QP PR P+ ++ PS PPP Sbjct: 759 TPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPP 812 Score = 38.1 bits (87), Expect = 0.012 Identities = 44/161 (27%), Positives = 60/161 (37%), Gaps = 23/161 (14%) Query: 55 GLGSPERP--PKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPE 112 G GSP +P P ++ + + + S Q QP+ A S Q L + P SP Sbjct: 572 GDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQ----LSMGQPHNAAGPSPH 627 Query: 113 SPR--------CQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPY 164 + R PKP P G +S +Q+ L+P P P P + Sbjct: 628 TLRRAVKKPAPAPPKPGNPPP--GHPGGQSSSGTSQHPPSLSPKPPTRS----PSPPTQH 681 Query: 165 PGQQAPGPEPSQPLLELTPRAPGSPRGQ-HEPSKPPPAGET 204 GQ P +PS P PR S P+ PPP T Sbjct: 682 TGQ--PPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPT 720 >gi|54860105 nadrin isoform 2 [Homo sapiens] Length = 803 Score = 55.1 bits (131), Expect = 1e-07 Identities = 53/174 (30%), Positives = 68/174 (39%), Gaps = 20/174 (11%) Query: 44 EPGSPPSVQRAGL---GSPERPPKTSPGSPRLQQGAGLE---SPQGQPE-PGAASPQRQQ 96 +PG+PP G G+ + PP SP P + P GQP P S R+ Sbjct: 564 KPGNPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRY 623 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQ---DQGVLASELAQNKEELTPGAPQHQ 153 L SP + P + P P Q P SQ + L SE + TP PQ Sbjct: 624 SSSL-SPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTP--PQTP 680 Query: 154 LPP-VPGSPEPYPGQQAP------GPEPSQPLLELTPRAPGSPRGQHEPSKPPP 200 PP P + P AP PE +QP PR P+ ++ PS PPP Sbjct: 681 TPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPP 734 Score = 39.3 bits (90), Expect = 0.006 Identities = 49/181 (27%), Positives = 64/181 (35%), Gaps = 23/181 (12%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQ---GQPEPGAASP 92 +S E + P S +V L E PPK G + Q GQ +P AA+ Sbjct: 473 DSGTLERKRPASM-AVMEGDLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAG 531 Query: 93 QRQQDLHLESPQRQPEYSPESPR--------CQPKPSEEAPKCSQDQGVLASELAQNKEE 144 Q L + P SP + R PKP P G +S +Q+ Sbjct: 532 SHQ--LSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNPPP--GHPGGQSSSGTSQHPPS 587 Query: 145 LTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQ-HEPSKPPPAGE 203 L+P P P P + GQ P +PS P PR S P+ PPP Sbjct: 588 LSPKPPTRS----PSPPTQHTGQ--PPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPP 641 Query: 204 T 204 T Sbjct: 642 T 642 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 55.1 bits (131), Expect = 1e-07 Identities = 59/211 (27%), Positives = 79/211 (37%), Gaps = 15/211 (7%) Query: 39 PEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDL 98 P + P PP+ Q E+P PG L Q G+ Q +PG A P QQ Sbjct: 362 PAQPLGPAKPPAQQTGS----EKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQQVG 416 Query: 99 HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVP 158 + +QP +SP P P++ + + A + K P +P Sbjct: 417 TPKPLAQQPGL--QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474 Query: 159 GSPEPYPGQQAPG-PEPSQPLLELTP-RAPGS---PRGQHEPSKPPP--AGETVTGGFGA 211 G +P P Q P P P QP P + PGS P Q P+KP P G T Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534 Query: 212 KKRKGSSSQ-APASKKLNKEELPVIPKGKPK 241 K S+ Q +PA + PV G K Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565 Score = 50.1 bits (118), Expect = 3e-06 Identities = 45/166 (27%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Query: 42 TREPGSP-PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQR----QQ 96 T++ G+P P Q+ GL SP + P P +QQ + P Q PG S Q+ + Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAP--GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPP 156 L P + P P + P+ A SQ G ++ P P Q P Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG----STKPPPQQPGPAKPSPQQPG 525 Query: 157 VPGSPEPYPGQQAPG---PEPSQPLLELTPRAPGSPRGQHEPSKPP 199 P PG P P P++P + + + P S G +P +PP Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTK-PVSQTGSGKPLQPP 570 Score = 46.6 bits (109), Expect = 3e-05 Identities = 88/386 (22%), Positives = 142/386 (36%), Gaps = 85/386 (22%) Query: 42 TREPGS---PPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDL 98 +++PGS PP SP++P T P P Q G+ S Q QP P S Q+ Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKP--PSQQPGSAKPSAQ-QPSPAKPSAQQSTKP 557 Query: 99 HLESPQRQPEYSPE-SPRCQPKPSEEAPK-----------------------CSQDQGVL 134 ++ +P P SP + PS+ PK C++ Q + Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617 Query: 135 AS--------ELAQNKEELTPGAPQHQ-----LPPVPGSPEPY-----------PGQQAP 170 S L + KE L + L PVP SP+P + +P Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSP 677 Query: 171 GPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGE--TVTGGFGAKKR---KGSSSQAPASK 225 P+ + P + P+ S EP KPPP + T+ G AK + + S PA Sbjct: 678 QPQQTSPKKDAAPKQDLSK--APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735 Query: 226 K----LNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKP--LRTSWQRKMKERQERKL 279 K ++++ + KPK ++ K + S KP + Q + +E+ L Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795 Query: 280 AKDFARHLEE-----EKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAK-K 333 D A+ + EK K R A ++I +P +K + Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSK------------AIPRPASDSKIISHPGPSSESKGQ 843 Query: 334 KQLRSIEKRDTLALLQKQPPQQPAAK 359 KQ+ ++K++ Q + +P AK Sbjct: 844 KQVDPVQKKEEPKKAQTKMSPKPDAK 869 Score = 44.7 bits (104), Expect = 1e-04 Identities = 58/251 (23%), Positives = 93/251 (37%), Gaps = 35/251 (13%) Query: 36 ESNPEET--------REPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEP 87 E++ EET +E G P + + L ++PPK P QQG G + Q P Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPL--QQQPPKPIPK----QQGPGRDPLQQDGTP 236 Query: 88 GAASPQRQQDLHLESPQ-----RQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNK 142 + S Q+ + + + P + P +P++ + +A + Q + Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV-----RG 291 Query: 143 EELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPG--------SPRGQHE 194 E + P P PP+ P Q PG E SQP P P P Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351 Query: 195 PSKPPPAGETVTGGFGAKK--RKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKK 252 P +PP + G K + + S+ P+S++ + L P G K+ +K Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL-AQPPGVGKTPAQQPGPAKP 410 Query: 253 RFSQMLQDKPL 263 Q+ KPL Sbjct: 411 PTQQVGTPKPL 421 Score = 43.9 bits (102), Expect = 2e-04 Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 15/138 (10%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPG--SPRLQQGAGLESPQGQP-------- 85 ++ P +T + P+ + L P +PP PG P QQ + P QP Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512 Query: 86 EPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEEL 145 +PG A P QQ + P +QP + S + QP P++ + +Q S+ K Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ-QPSPAKPS---AQQSTKPVSQTGSGKPLQ 568 Query: 146 TPG-APQHQLPPVPGSPE 162 P +P + PP G P+ Sbjct: 569 PPTVSPSAKQPPSQGLPK 586 Score = 43.1 bits (100), Expect = 4e-04 Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 31/213 (14%) Query: 37 SNPEETREPGSPPSVQRAGLGS--PERPPKTSPGSPRLQQGAGLESP-------QGQPEP 87 S P +EP P +A + P++P P + + + P Q Q E Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789 Query: 88 GAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTP 147 P L +S + + P + P S+ P+ + D +++ ++ + Sbjct: 790 KTTPP-----LKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK--- 841 Query: 148 GAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTG 207 Q Q+ PV EP Q P+P + P GSP P P AG+TV Sbjct: 842 --GQKQVDPVQKKEEPKKAQTKMSPKP-----DAKPMPKGSPT---PPGPRPTAGQTVPT 891 Query: 208 GFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 + K + S + LN + PK +P Sbjct: 892 PQQSPKPQEQSRRF----SLNLGSITDAPKSQP 920 Score = 41.6 bits (96), Expect = 0.001 Identities = 57/223 (25%), Positives = 83/223 (37%), Gaps = 38/223 (17%) Query: 33 VEFESNPEETREPGSP-PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAAS 91 V+ + P++ + SP P + GSP +P PR G + +PQ P+P S Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSP------TPPGPRPTAGQTVPTPQQSPKPQEQS 902 Query: 92 PQRQQDLHLESPQRQPEYSPESPR--CQPKPSEEAPKCSQDQGVLASELAQN--KEELTP 147 R+ L+L S P+ P +P+ K L S Q + P Sbjct: 903 --RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960 Query: 148 GAPQHQLP-----PVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGS----PRGQHEPS-- 196 GAP Q P P P GQ P P S P+ + T +AP + P+ + P+ Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET-KAPAAEKLEPKAEQAPTVK 1019 Query: 197 ------KPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELP 233 KPPP + +K +A KL K P Sbjct: 1020 RTETEKKPPPIKD-------SKSLTAEPQKAVLPTKLEKSPKP 1055 Score = 39.7 bits (91), Expect = 0.004 Identities = 82/360 (22%), Positives = 133/360 (36%), Gaps = 65/360 (18%) Query: 1 MDTPLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPE 60 M T RR R+G + +S+T +T+ L + S +T + SVQ +G+ Sbjct: 3484 MPTRSRRKARVG----KYGDSMTEADKTK-PLSKVSSIAVQTV---AEISVQTEPVGTIR 3535 Query: 61 RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP 120 P + +++ + +P+ + G+ Q + D +SPQ SP + +P P Sbjct: 3536 TPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTP 3595 Query: 121 SE--------------EAPKCSQDQGVLASELAQNKEELTPG------------------ 148 E AP + VL S ++ L+PG Sbjct: 3596 LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPIS----PLSPGKALESAFVPYEKPLPDDI 3651 Query: 149 APQHQLPP-----VPGSPEPYPGQQ--APGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA 201 +PQ L P P SP+ Q P+P P + + RAP Q+ Sbjct: 3652 SPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAP----FQYTEGYTTKG 3707 Query: 202 GETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDK 261 +T+T KK K + P + + G R+ + + R +++LQD Sbjct: 3708 SQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMAR-AKILQD- 3765 Query: 262 PLRTSWQRKMKERQERKLAKDFARHLEEEKE-----RRRQEKKQRRAENLKRRLENERKA 316 + + ER+ KL K A EEEKE R + RR E L + E +A Sbjct: 3766 ---IDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERA 3822 Score = 32.7 bits (73), Expect = 0.52 Identities = 60/301 (19%), Positives = 108/301 (35%), Gaps = 68/301 (22%) Query: 57 GSPERPPKTSPGSPRLQQGAGLESPQGQPEP---GAASPQRQQDLHLESPQRQPEYSPES 113 G P ++ PG+P Q A + P Q P G A P + + P ++ +P + Sbjct: 950 GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI----PVKKETKAPAA 1005 Query: 114 PRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAP--- 170 + +PK +E+AP + + ++ + LT PQ + P P P P Sbjct: 1006 EKLEPK-AEQAPTVKRTETEKKPPPIKDSKSLT-AEPQKAVLPTKLEKSPKPESTCPLCK 1063 Query: 171 ---------------------------GPEPSQPLLEL---------TPRAPGSPRGQHE 194 G P+ L E+ T RA G Sbjct: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIR 1123 Query: 195 PSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRF 254 P P+G + + + P KL K++ + K ++ +V ++ K+ Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV---KTEAEKVILEKVKETL 1180 Query: 255 SQMLQDKPLRTSWQRKMKER----------------QERKLAKDFARHLEEEKERRRQEK 298 S M + P+ T+ Q++ + + +E+KL + + EEK+ +EK Sbjct: 1181 S-MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239 Query: 299 K 299 K Sbjct: 1240 K 1240 Score = 31.6 bits (70), Expect = 1.2 Identities = 70/385 (18%), Positives = 135/385 (35%), Gaps = 53/385 (13%) Query: 13 GLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRL 72 G P +P V + +A + P+ + P +V+R P K S Sbjct: 984 GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP----TVKRTETEKKPPPIKDSKSLTAE 1039 Query: 73 QQGAGLESP-QGQPEPGAASPQRQQDLHLESPQRQPEYSP----ESPRCQPKPSEEAPKC 127 Q A L + + P+P + P + +L++ S P ++ ++ C P Sbjct: 1040 PQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD-PPNFNTCTECKNQVCNLCGFNPTPHL 1098 Query: 128 SQDQGVLASELAQNKEELTPGAPQHQLPPVPG----SPEPYPGQQAPGPEPSQPLLELTP 183 ++ Q L + ++PP P SP P P + + P ++L Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVK 1158 Query: 184 RAPGSPRGQHEP------------SKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEE 231 + + + E K PP T K+ + + AS K+ Sbjct: 1159 KQEQEVKTEAEKVILEKVKETLSMEKIPPMVTT-----DQKQEESKLEKDKASALQEKKP 1213 Query: 232 LPVIPKGKPKSGRVWKDRSKKRFSQML---QDKPLRTSWQRKMKERQERKLAKDFARHLE 288 LP K P+ ++ + K + +DK L + E Q+ L K + E Sbjct: 1214 LPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAE 1273 Query: 289 EEKERRRQEKKQRRAENLKRRL-------------ENERKAEVVQ------VIRNPAKLK 329 E+ E R K + + + ++ E+++ + ++ P +++ Sbjct: 1274 EKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVE 1333 Query: 330 RAKKKQLRSIEKRDTLALLQKQPPQ 354 K+K + +K DT + Q + PQ Sbjct: 1334 PGKEKTEKEDDKSDTSSSQQPKSPQ 1358 Score = 30.4 bits (67), Expect = 2.6 Identities = 29/112 (25%), Positives = 40/112 (35%), Gaps = 10/112 (8%) Query: 155 PPVPGSPEPYPGQQA--PGPEPSQPLLELTPRAPGSPRGQHEPS--KPPPAGETVTGGFG 210 PPVP P P PEPS+P + P P P +P+ P P G ++T Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT 2543 Query: 211 AKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKP 262 + A KL P+ P S R K ++ L +P Sbjct: 2544 L------NLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP 2589 Score = 29.6 bits (65), Expect = 4.4 Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 4/72 (5%) Query: 117 QPKPSEEAPKCSQDQGVLASE----LAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGP 172 Q KP+ + P S L ++ + +++ P PP P P P P P P Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428 Query: 173 EPSQPLLELTPR 184 P+ P + P+ Sbjct: 2429 PPTSPKPTILPK 2440 Score = 28.9 bits (63), Expect = 7.5 Identities = 44/218 (20%), Positives = 72/218 (33%), Gaps = 8/218 (3%) Query: 23 TSVSRTRRALVEFESNPE--ETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLES 80 T T +L F NP E +E + LG P +SP P+L+ + Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP-QPKLKTAPVTTT 669 Query: 81 PQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQ 140 +SPQ QQ + + + S +P P + P A + + Sbjct: 670 SA----VSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725 Query: 141 NKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSK-PP 199 P P+ P P + P+ +P +L + + + SK Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785 Query: 200 PAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPK 237 A E T K S S P +K++ + IP+ Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823 Score = 28.5 bits (62), Expect = 9.8 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 14/137 (10%) Query: 41 ETREPGSPPSVQRAGL--GSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDL 98 +T + G P + GL G+P+ PK + + + + QP+P + Q + Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK--------TIKEQPQPPCTAKPDQVEP 1334 Query: 99 HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVP 158 E +++ + S S QPK +P+ D G + ++ + E+ P + + Sbjct: 1335 GKEKTEKEDDKSDTSSSQQPK----SPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILK 1390 Query: 159 GSPEPYPGQQAPGPEPS 175 G + Q++ PS Sbjct: 1391 GLKKDSFSQESSPSSPS 1407 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 55.1 bits (131), Expect = 1e-07 Identities = 59/211 (27%), Positives = 79/211 (37%), Gaps = 15/211 (7%) Query: 39 PEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDL 98 P + P PP+ Q E+P PG L Q G+ Q +PG A P QQ Sbjct: 362 PAQPLGPAKPPAQQTGS----EKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQQVG 416 Query: 99 HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVP 158 + +QP +SP P P++ + + A + K P +P Sbjct: 417 TPKPLAQQPGL--QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLP 474 Query: 159 GSPEPYPGQQAPG-PEPSQPLLELTP-RAPGS---PRGQHEPSKPPP--AGETVTGGFGA 211 G +P P Q P P P QP P + PGS P Q P+KP P G T Sbjct: 475 GPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534 Query: 212 KKRKGSSSQ-APASKKLNKEELPVIPKGKPK 241 K S+ Q +PA + PV G K Sbjct: 535 GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565 Score = 50.1 bits (118), Expect = 3e-06 Identities = 45/166 (27%), Positives = 66/166 (39%), Gaps = 15/166 (9%) Query: 42 TREPGSP-PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQR----QQ 96 T++ G+P P Q+ GL SP + P P +QQ + P Q PG S Q+ + Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAP--GPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP 469 Query: 97 DLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPP 156 L P + P P + P+ A SQ G ++ P P Q P Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG----STKPPPQQPGPAKPSPQQPG 525 Query: 157 VPGSPEPYPGQQAPG---PEPSQPLLELTPRAPGSPRGQHEPSKPP 199 P PG P P P++P + + + P S G +P +PP Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTK-PVSQTGSGKPLQPP 570 Score = 46.6 bits (109), Expect = 3e-05 Identities = 88/386 (22%), Positives = 142/386 (36%), Gaps = 85/386 (22%) Query: 42 TREPGS---PPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDL 98 +++PGS PP SP++P T P P Q G+ S Q QP P S Q+ Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKP--PSQQPGSAKPSAQ-QPSPAKPSAQQSTKP 557 Query: 99 HLESPQRQPEYSPE-SPRCQPKPSEEAPK-----------------------CSQDQGVL 134 ++ +P P SP + PS+ PK C++ Q + Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617 Query: 135 AS--------ELAQNKEELTPGAPQHQ-----LPPVPGSPEPY-----------PGQQAP 170 S L + KE L + L PVP SP+P + +P Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSP 677 Query: 171 GPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGE--TVTGGFGAKKR---KGSSSQAPASK 225 P+ + P + P+ S EP KPPP + T+ G AK + + S PA Sbjct: 678 QPQQTSPKKDAAPKQDLSK--APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735 Query: 226 K----LNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKP--LRTSWQRKMKERQERKL 279 K ++++ + KPK ++ K + S KP + Q + +E+ L Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795 Query: 280 AKDFARHLEE-----EKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAK-K 333 D A+ + EK K R A ++I +P +K + Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSK------------AIPRPASDSKIISHPGPSSESKGQ 843 Query: 334 KQLRSIEKRDTLALLQKQPPQQPAAK 359 KQ+ ++K++ Q + +P AK Sbjct: 844 KQVDPVQKKEEPKKAQTKMSPKPDAK 869 Score = 44.7 bits (104), Expect = 1e-04 Identities = 58/251 (23%), Positives = 93/251 (37%), Gaps = 35/251 (13%) Query: 36 ESNPEET--------REPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEP 87 E++ EET +E G P + + L ++PPK P QQG G + Q P Sbjct: 183 EASQEETTKKQKVVQKEQGKPEGIIKPPL--QQQPPKPIPK----QQGPGRDPLQQDGTP 236 Query: 88 GAASPQRQQDLHLESPQ-----RQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNK 142 + S Q+ + + + P + P +P++ + +A + Q + Sbjct: 237 KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIV-----RG 291 Query: 143 EELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPG--------SPRGQHE 194 E + P P PP+ P Q PG E SQP P P P Sbjct: 292 ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351 Query: 195 PSKPPPAGETVTGGFGAKK--RKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKK 252 P +PP + G K + + S+ P+S++ + L P G K+ +K Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL-AQPPGVGKTPAQQPGPAKP 410 Query: 253 RFSQMLQDKPL 263 Q+ KPL Sbjct: 411 PTQQVGTPKPL 421 Score = 43.9 bits (102), Expect = 2e-04 Identities = 37/138 (26%), Positives = 58/138 (42%), Gaps = 15/138 (10%) Query: 36 ESNPEETREPGSPPSVQRAGLGSPERPPKTSPG--SPRLQQGAGLESPQGQP-------- 85 ++ P +T + P+ + L P +PP PG P QQ + P QP Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ 512 Query: 86 EPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEEL 145 +PG A P QQ + P +QP + S + QP P++ + +Q S+ K Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ-QPSPAKPS---AQQSTKPVSQTGSGKPLQ 568 Query: 146 TPG-APQHQLPPVPGSPE 162 P +P + PP G P+ Sbjct: 569 PPTVSPSAKQPPSQGLPK 586 Score = 43.1 bits (100), Expect = 4e-04 Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 31/213 (14%) Query: 37 SNPEETREPGSPPSVQRAGLGS--PERPPKTSPGSPRLQQGAGLESP-------QGQPEP 87 S P +EP P +A + P++P P + + + P Q Q E Sbjct: 730 SKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789 Query: 88 GAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTP 147 P L +S + + P + P S+ P+ + D +++ ++ + Sbjct: 790 KTTPP-----LKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESK--- 841 Query: 148 GAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVTG 207 Q Q+ PV EP Q P+P + P GSP P P AG+TV Sbjct: 842 --GQKQVDPVQKKEEPKKAQTKMSPKP-----DAKPMPKGSPT---PPGPRPTAGQTVPT 891 Query: 208 GFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP 240 + K + S + LN + PK +P Sbjct: 892 PQQSPKPQEQSRRF----SLNLGSITDAPKSQP 920 Score = 41.6 bits (96), Expect = 0.001 Identities = 57/223 (25%), Positives = 83/223 (37%), Gaps = 38/223 (17%) Query: 33 VEFESNPEETREPGSP-PSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAAS 91 V+ + P++ + SP P + GSP +P PR G + +PQ P+P S Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSP------TPPGPRPTAGQTVPTPQQSPKPQEQS 902 Query: 92 PQRQQDLHLESPQRQPEYSPESPR--CQPKPSEEAPKCSQDQGVLASELAQN--KEELTP 147 R+ L+L S P+ P +P+ K L S Q + P Sbjct: 903 --RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGP 960 Query: 148 GAPQHQLP-----PVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGS----PRGQHEPS-- 196 GAP Q P P P GQ P P S P+ + T +AP + P+ + P+ Sbjct: 961 GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKET-KAPAAEKLEPKAEQAPTVK 1019 Query: 197 ------KPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELP 233 KPPP + +K +A KL K P Sbjct: 1020 RTETEKKPPPIKD-------SKSLTAEPQKAVLPTKLEKSPKP 1055 Score = 39.7 bits (91), Expect = 0.004 Identities = 82/360 (22%), Positives = 133/360 (36%), Gaps = 65/360 (18%) Query: 1 MDTPLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPE 60 M T RR R+G + +S+T +T+ L + S +T + SVQ +G+ Sbjct: 3484 MPTRSRRKARVG----KYGDSMTEADKTK-PLSKVSSIAVQTV---AEISVQTEPVGTIR 3535 Query: 61 RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP 120 P + +++ + +P+ + G+ Q + D +SPQ SP + +P P Sbjct: 3536 TPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTP 3595 Query: 121 SE--------------EAPKCSQDQGVLASELAQNKEELTPG------------------ 148 E AP + VL S ++ L+PG Sbjct: 3596 LEIGYSSHLRADSTVQLAPSPPKSPKVLYSPIS----PLSPGKALESAFVPYEKPLPDDI 3651 Query: 149 APQHQLPP-----VPGSPEPYPGQQ--APGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA 201 +PQ L P P SP+ Q P+P P + + RAP Q+ Sbjct: 3652 SPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAP----FQYTEGYTTKG 3707 Query: 202 GETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDK 261 +T+T KK K + P + + G R+ + + R +++LQD Sbjct: 3708 SQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRRRICRTNTMAR-AKILQD- 3765 Query: 262 PLRTSWQRKMKERQERKLAKDFARHLEEEKE-----RRRQEKKQRRAENLKRRLENERKA 316 + + ER+ KL K A EEEKE R + RR E L + E +A Sbjct: 3766 ---IDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRERA 3822 Score = 32.7 bits (73), Expect = 0.52 Identities = 60/301 (19%), Positives = 108/301 (35%), Gaps = 68/301 (22%) Query: 57 GSPERPPKTSPGSPRLQQGAGLESPQGQPEP---GAASPQRQQDLHLESPQRQPEYSPES 113 G P ++ PG+P Q A + P Q P G A P + + P ++ +P + Sbjct: 950 GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSI----PVKKETKAPAA 1005 Query: 114 PRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAP--- 170 + +PK +E+AP + + ++ + LT PQ + P P P P Sbjct: 1006 EKLEPK-AEQAPTVKRTETEKKPPPIKDSKSLT-AEPQKAVLPTKLEKSPKPESTCPLCK 1063 Query: 171 ---------------------------GPEPSQPLLEL---------TPRAPGSPRGQHE 194 G P+ L E+ T RA G Sbjct: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIR 1123 Query: 195 PSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRF 254 P P+G + + + P KL K++ + K ++ +V ++ K+ Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV---KTEAEKVILEKVKETL 1180 Query: 255 SQMLQDKPLRTSWQRKMKER----------------QERKLAKDFARHLEEEKERRRQEK 298 S M + P+ T+ Q++ + + +E+KL + + EEK+ +EK Sbjct: 1181 S-MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEK 1239 Query: 299 K 299 K Sbjct: 1240 K 1240 Score = 31.6 bits (70), Expect = 1.2 Identities = 70/385 (18%), Positives = 135/385 (35%), Gaps = 53/385 (13%) Query: 13 GLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRL 72 G P +P V + +A + P+ + P +V+R P K S Sbjct: 984 GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP----TVKRTETEKKPPPIKDSKSLTAE 1039 Query: 73 QQGAGLESP-QGQPEPGAASPQRQQDLHLESPQRQPEYSP----ESPRCQPKPSEEAPKC 127 Q A L + + P+P + P + +L++ S P ++ ++ C P Sbjct: 1040 PQKAVLPTKLEKSPKPESTCPLCKTELNIGSKD-PPNFNTCTECKNQVCNLCGFNPTPHL 1098 Query: 128 SQDQGVLASELAQNKEELTPGAPQHQLPPVPG----SPEPYPGQQAPGPEPSQPLLELTP 183 ++ Q L + ++PP P SP P P + + P ++L Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVK 1158 Query: 184 RAPGSPRGQHEP------------SKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEE 231 + + + E K PP T K+ + + AS K+ Sbjct: 1159 KQEQEVKTEAEKVILEKVKETLSMEKIPPMVTT-----DQKQEESKLEKDKASALQEKKP 1213 Query: 232 LPVIPKGKPKSGRVWKDRSKKRFSQML---QDKPLRTSWQRKMKERQERKLAKDFARHLE 288 LP K P+ ++ + K + +DK L + E Q+ L K + E Sbjct: 1214 LPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAE 1273 Query: 289 EEKERRRQEKKQRRAENLKRRL-------------ENERKAEVVQ------VIRNPAKLK 329 E+ E R K + + + ++ E+++ + ++ P +++ Sbjct: 1274 EKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVE 1333 Query: 330 RAKKKQLRSIEKRDTLALLQKQPPQ 354 K+K + +K DT + Q + PQ Sbjct: 1334 PGKEKTEKEDDKSDTSSSQQPKSPQ 1358 Score = 30.4 bits (67), Expect = 2.6 Identities = 29/112 (25%), Positives = 40/112 (35%), Gaps = 10/112 (8%) Query: 155 PPVPGSPEPYPGQQA--PGPEPSQPLLELTPRAPGSPRGQHEPS--KPPPAGETVTGGFG 210 PPVP P P PEPS+P + P P P +P+ P P G ++T Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT 2543 Query: 211 AKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKP 262 + A KL P+ P S R K ++ L +P Sbjct: 2544 L------NLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEP 2589 Score = 29.6 bits (65), Expect = 4.4 Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 4/72 (5%) Query: 117 QPKPSEEAPKCSQDQGVLASE----LAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGP 172 Q KP+ + P S L ++ + +++ P PP P P P P P P Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428 Query: 173 EPSQPLLELTPR 184 P+ P + P+ Sbjct: 2429 PPTSPKPTILPK 2440 Score = 28.9 bits (63), Expect = 7.5 Identities = 44/218 (20%), Positives = 72/218 (33%), Gaps = 8/218 (3%) Query: 23 TSVSRTRRALVEFESNPE--ETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLES 80 T T +L F NP E +E + LG P +SP P+L+ + Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP-QPKLKTAPVTTT 669 Query: 81 PQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQ 140 +SPQ QQ + + + S +P P + P A + + Sbjct: 670 SA----VSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPE 725 Query: 141 NKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSK-PP 199 P P+ P P + P+ +P +L + + + SK Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785 Query: 200 PAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPK 237 A E T K S S P +K++ + IP+ Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPR 823 Score = 28.5 bits (62), Expect = 9.8 Identities = 28/137 (20%), Positives = 56/137 (40%), Gaps = 14/137 (10%) Query: 41 ETREPGSPPSVQRAGL--GSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDL 98 +T + G P + GL G+P+ PK + + + + QP+P + Q + Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTK--------TIKEQPQPPCTAKPDQVEP 1334 Query: 99 HLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVP 158 E +++ + S S QPK +P+ D G + ++ + E+ P + + Sbjct: 1335 GKEKTEKEDDKSDTSSSQQPK----SPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILK 1390 Query: 159 GSPEPYPGQQAPGPEPS 175 G + Q++ PS Sbjct: 1391 GLKKDSFSQESSPSSPS 1407 >gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 preproprotein [Homo sapiens] Length = 178 Score = 54.3 bits (129), Expect = 2e-07 Identities = 51/159 (32%), Positives = 63/159 (39%), Gaps = 20/159 (12%) Query: 46 GSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQR 105 G+P G P+ PP PG P+ G PQG P PG PQ PQ Sbjct: 34 GNPQGPSPQGGNKPQGPPPP-PGKPQGPPPQGGNKPQGPPPPG--KPQGPP------PQG 84 Query: 106 QPEYSPESPRCQPK---PSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPE 162 SP SP +P+ P P+ QG S+ A++ G PQ + G P Sbjct: 85 DKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP 144 Query: 163 PYPG--QQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPP 199 P G QQ P QP + PR P R PS+PP Sbjct: 145 PAGGNPQQPQAPPAGQP--QGPPRPPQGGR----PSRPP 177 Score = 39.7 bits (91), Expect = 0.004 Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 9/102 (8%) Query: 15 RPESPESLTSVSRTRRALV-EFESNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQ 73 +P+ P SR+ R+ + + P + +P PP+ Q R P P P Q Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPA-QGGSKSQSARSPPGKPQGPPQQ 134 Query: 74 QGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPR 115 +G +PQG P P +PQ+ Q P QP+ P P+ Sbjct: 135 EG---NNPQGPPPPAGGNPQQPQ----APPAGQPQGPPRPPQ 169 Score = 35.8 bits (81), Expect = 0.061 Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 5/79 (6%) Query: 147 PGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGETVT 206 PG PQ PP G +P G PG P R+P SP G +P PPP G Sbjct: 54 PGKPQG--PPPQGGNKP-QGPPPPGKPQGPPPQGDKSRSPRSPPG--KPQGPPPQGGKPQ 108 Query: 207 GGFGAKKRKGSSSQAPASK 225 G K S+++P K Sbjct: 109 GPPAQGGSKSQSARSPPGK 127 Score = 33.5 bits (75), Expect = 0.30 Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 24/120 (20%) Query: 133 VLASELAQNKEELTPGAPQHQLPPV----PGSPEPYPGQQAPGPEPSQPLLELTPRAPGS 188 +LA AQN E Q + P + P P P G + GP P PG Sbjct: 10 LLALSSAQNLNE---DVSQEESPSLIAGNPQGPSPQGGNKPQGPPPP----------PGK 56 Query: 189 PRGQ-----HEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSG 243 P+G ++P PPP G+ G + K S ++P K P+G P G Sbjct: 57 PQGPPPQGGNKPQGPPPPGK--PQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQG 114 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 53.9 bits (128), Expect = 2e-07 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 4/136 (2%) Query: 212 KKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKM 271 K+R+ + +K K E K K K K+R +KR + Q K R +RK Sbjct: 38 KERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKR 97 Query: 272 KERQERKLAKDFARH----LEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAK 327 K+ ++++ K R +E KER R+ K++R + KRR + RK + R + Sbjct: 98 KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE 157 Query: 328 LKRAKKKQLRSIEKRD 343 KR K+K+ +KR+ Sbjct: 158 RKRKKRKKEEREKKRE 173 Score = 51.2 bits (121), Expect = 1e-06 Identities = 33/119 (27%), Positives = 62/119 (52%), Gaps = 1/119 (0%) Query: 225 KKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFA 284 +K KE+ K + + R K K+R + Q + + +RK K R+ERK K+ Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154 Query: 285 RHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRD 343 + + K+R+++E++++R N K R + ER+ + + + K +R KKK+ + K D Sbjct: 155 KRERKRKKRKKEEREKKRERNRKER-KKERERKERRERKKERKKERRKKKERKKDRKTD 212 Score = 47.8 bits (112), Expect = 2e-05 Identities = 33/135 (24%), Positives = 72/135 (53%), Gaps = 6/135 (4%) Query: 212 KKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKM 271 +KRK Q ++ + + K + + R ++R KK+ + +++ + +RK Sbjct: 77 RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK-ERKERERENKQRRERKR 135 Query: 272 KERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLE---NERKAEVVQVIRNPAKL 328 K+R+++K K+ R E+E+ +R +++K+R+ E +++ E ERK E + R K Sbjct: 136 KKRRKKKRRKE--RKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193 Query: 329 KRAKKKQLRSIEKRD 343 +R K+++ + K+D Sbjct: 194 ERKKERRKKKERKKD 208 Score = 42.0 bits (97), Expect = 9e-04 Identities = 34/117 (29%), Positives = 59/117 (50%), Gaps = 14/117 (11%) Query: 239 KPKSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKER---QERK---LAKDFARHLEEEKE 292 + K R + R ++R + +++ + +RK +ER +ERK K E+E+ Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95 Query: 293 RRRQEKKQR------RAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRD 343 +R++EKK+R R E K++ ER+ E Q R K K+ +KK+ R KR+ Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKERERENKQ--RRERKRKKRRKKKRRKERKRE 150 Score = 41.2 bits (95), Expect = 0.001 Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 1/82 (1%) Query: 261 KPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQ 320 KP + KER+ER+ K R E ++ER ++EKK+R+ + E +RK Q Sbjct: 27 KPCTQRESERKKERREREKRKR-EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85 Query: 321 VIRNPAKLKRAKKKQLRSIEKR 342 K +R +KK+ + E++ Sbjct: 86 RKERREKERRKRKKEKKKRERK 107 Score = 40.4 bits (93), Expect = 0.002 Identities = 25/97 (25%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Query: 250 SKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQE----KKQRRAEN 305 S+++ + ++K R + + +ER +++ K R +E+ER+R+E +K+RR + Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93 Query: 306 LKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKR 342 ++R + ++K E Q R K K+ +K++ R ++R Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR 130 Score = 37.7 bits (86), Expect = 0.016 Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 18/137 (13%) Query: 190 RGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDR 249 RG+ E K E ++RK + +K K E + + + R ++R Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168 Query: 250 SKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRR 309 KKR + K +R+ KER+ERK +E+++ R++KK+R+ + R+ Sbjct: 169 EKKRERNRKERKK-----ERERKERRERK----------KERKKERRKKKERKKD---RK 210 Query: 310 LENERKAEVVQVIRNPA 326 + + ++V + +R A Sbjct: 211 TDRQTDSQVFRPLRESA 227 Score = 29.6 bits (65), Expect = 4.4 Identities = 14/57 (24%), Positives = 30/57 (52%) Query: 279 LAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQ 335 ++K + E K+ RR+ +K++R +R+ E +K + + R K + K+K+ Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKE 81 >gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] Length = 2285 Score = 53.9 bits (128), Expect = 2e-07 Identities = 47/169 (27%), Positives = 67/169 (39%), Gaps = 27/169 (15%) Query: 45 PGSPPSVQRAGLGSPERPPKTSPGSPRLQQGA----------GLESPQGQPEPGAASPQR 94 PG P Q +P+R P T G + G G + P G + G Sbjct: 418 PGQPYGSQ-----TPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYN 472 Query: 95 QQDLHLESPQRQPEYSPESPRCQP--KPSEEAPKCSQDQGVLASELAQNKEELTPGAPQH 152 QQ H + Q+QP YS + P P +PS + SQ + +S+ P + Q Sbjct: 473 QQSPHPQ--QQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ--------PPYSQQP 522 Query: 153 QLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPA 201 PP SP PYP QQ+ + Q + SP Q +P +P P+ Sbjct: 523 SQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPS 571 Score = 44.7 bits (104), Expect = 1e-04 Identities = 40/143 (27%), Positives = 60/143 (41%), Gaps = 11/143 (7%) Query: 38 NPEETREPGS--PPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQ-- 93 +P++ + P S PPS S ++ P++ P P+LQ S Q P SP Sbjct: 477 HPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQP--PQLQSSQPPYSQQPSQPPHQQSPAPY 534 Query: 94 -RQQDLHLESPQRQPEYSP---ESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGA 149 QQ + PQ QP YS +SP Q +P + AP Q +Q ++ T + Sbjct: 535 PSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQ-TAYS 593 Query: 150 PQHQLPPVPGSPEPYPGQQAPGP 172 Q PP S + + Q + P Sbjct: 594 QQRFPPPQELSQDSFGSQASSAP 616 Score = 39.3 bits (90), Expect = 0.006 Identities = 41/145 (28%), Positives = 58/145 (40%), Gaps = 22/145 (15%) Query: 39 PEETREPGSP-----PSVQRAGLGSPER-PPKTSPGSPRLQQGAGLE-SPQGQPEPGAAS 91 PE G+P PS +G+ SP R PP+ + G + S QG P G+ Sbjct: 1296 PEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPS-GSPF 1354 Query: 92 PQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ 151 P +Q ++ Q+Q Y +P P + +G + S + G PQ Sbjct: 1355 PSQQTTMY---QQQQQNYK------RPMDGTYGPPAKRHEGEMYSVPYSTGQ----GQPQ 1401 Query: 152 HQLPPVPGSPEPYPGQQAPGPEPSQ 176 Q P P P+P QQA P P Q Sbjct: 1402 QQQLP-PAQPQPASQQQAAQPSPQQ 1425 Score = 36.6 bits (83), Expect = 0.036 Identities = 65/335 (19%), Positives = 117/335 (34%), Gaps = 34/335 (10%) Query: 46 GSPPSVQRAGLGSPERPPK-----TSPGSPRLQQGAGLESPQGQPEPG------------ 88 G PS G P P TSP S R QG G P+ G Sbjct: 276 GGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQ 335 Query: 89 ---AASPQRQQDLHLESPQRQPEYSPESPRCQP---KPSEEAPKCSQDQGVLASELAQNK 142 AA+ Q++ ++P SP +P P+ S + Q Sbjct: 336 CWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPY 395 Query: 143 EELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAG 202 P + Q P P YPGQ P + + + RA + G + PP G Sbjct: 396 GGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYG 455 Query: 203 ETVTGGFGAK-KRKGSSSQAPASKKLNKEELPVIPKGKPKSGRVWKDRSKKRFSQMLQDK 261 + G+G + + + Q+P ++ P P + ++ + + + Q+ + Sbjct: 456 QQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQ 515 Query: 262 PLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQRRAENLKRRLENERKAEVVQV 321 P S Q Q+ + ++ + + Q +A++ ++ + ++ A Sbjct: 516 P-PYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA----- 569 Query: 322 IRNPAKL-KRAKKKQLRSIEKRDTLALLQKQPPQQ 355 P+ L ++A Q +S + + T Q+ PP Q Sbjct: 570 ---PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQ 601 Score = 33.9 bits (76), Expect = 0.23 Identities = 49/209 (23%), Positives = 77/209 (36%), Gaps = 29/209 (13%) Query: 37 SNPEETREPGSPPSVQRAG-----LGSPERPPKTSPGSPRLQQGAGLESPQGQPEPGAAS 91 S P +++P PP Q + ++ P++ P P Q A Q QP+ A S Sbjct: 514 SQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQP--PYSQPQAQSPYQQQQPQQPAPS 571 Query: 92 PQRQQDLHLESPQRQPEYSPESPRCQPKPSEEA-----PKCSQDQGVLASELAQNKEELT 146 QQ + + +Q + + S + P P E + + S + +S+ Q L+ Sbjct: 572 TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLS 631 Query: 147 PGAPQHQLPPVPGSPEPY---------PGQQAPGPEPSQPLLELTPRAPGSPR-GQHEPS 196 + LP + GS + PG G SQ ++P SP H P Sbjct: 632 LQSRPSSLPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPG 691 Query: 197 ----KPPPAGETVTGGFGAKKRKGSSSQA 221 P P G + A+ R G S A Sbjct: 692 IRGPSPSPVGSPAS---VAQSRSGPLSPA 717 Score = 29.6 bits (65), Expect = 4.4 Identities = 27/98 (27%), Positives = 33/98 (33%), Gaps = 22/98 (22%) Query: 148 GAPQHQLPPVPGSPEPYPGQQA-PGPEPSQPLLELTPRAPGSPRGQHEPSKPPPAGET-- 204 G P HQ YP + A P P P+ L PGS SKPPP+ Sbjct: 206 GFPNHQYNSY------YPNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASA 259 Query: 205 -------------VTGGFGAKKRKGSSSQAPASKKLNK 229 GG G G + Q A+ LN+ Sbjct: 260 SSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQ 297 Score = 29.6 bits (65), Expect = 4.4 Identities = 17/59 (28%), Positives = 25/59 (42%), Gaps = 2/59 (3%) Query: 101 ESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPG 159 +S + QP+ P SP S + P+ Q +E K P Q+PP+PG Sbjct: 1122 DSKKSQPKIQPPSPA--GSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPG 1178 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.127 0.364 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,426,338 Number of Sequences: 37866 Number of extensions: 1513666 Number of successful extensions: 26113 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 699 Number of HSP's successfully gapped in prelim test: 2122 Number of HSP's that attempted gapping in prelim test: 10676 Number of HSP's gapped (non-prelim): 10152 length of query: 360 length of database: 18,247,518 effective HSP length: 103 effective length of query: 257 effective length of database: 14,347,320 effective search space: 3687261240 effective search space used: 3687261240 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.