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Search of human proteins with 109150419
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109150419 missing oocyte, meiosis regulator, homolog [Homo
sapiens]
(875 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109150419 missing oocyte, meiosis regulator, homolog [Homo sa... 1813 0.0
gi|58331266 WD repeat domain 59 [Homo sapiens] 50 7e-06
gi|14149987 WD repeat domain 24 [Homo sapiens] 50 1e-05
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 48 3e-05
gi|157739942 gemin 5 [Homo sapiens] 46 2e-04
gi|217330644 WD repeat domain 12 protein [Homo sapiens] 45 3e-04
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 45 4e-04
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 45 4e-04
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 45 4e-04
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 40 0.007
gi|14149696 SEC31 homolog B [Homo sapiens] 39 0.016
gi|239743654 PREDICTED: similar to block of proliferation 1 [Hom... 37 0.061
gi|21327667 block of proliferation 1 [Homo sapiens] 37 0.061
gi|109627650 coronin 6 [Homo sapiens] 37 0.080
gi|55741849 WD repeat domain 22 [Homo sapiens] 35 0.23
gi|59938780 WD repeat domain 31 isoform 1 [Homo sapiens] 35 0.23
gi|21687048 WD repeat domain 31 isoform 3 [Homo sapiens] 35 0.23
gi|119120894 Dmx-like 2 [Homo sapiens] 34 0.52
gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Hom... 34 0.52
gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Hom... 34 0.52
gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens] 34 0.68
gi|78482617 general transcription factor IIIC, polypeptide 2, be... 33 0.88
gi|4504205 general transcription factor IIIC, polypeptide 2, bet... 33 0.88
gi|4507703 tumor suppressing subtransferable candidate 1 [Homo s... 33 0.88
gi|148528998 Dmx-like 1 [Homo sapiens] 33 0.88
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 33 1.5
gi|66267730 WD repeat domain 34 [Homo sapiens] 33 1.5
gi|108936958 WD-repeat protein [Homo sapiens] 32 2.0
gi|84626578 G protein beta subunit-like [Homo sapiens] 32 2.0
gi|117956407 zinc finger protein 568 [Homo sapiens] 32 2.0
>gi|109150419 missing oocyte, meiosis regulator, homolog [Homo
sapiens]
Length = 875
Score = 1813 bits (4695), Expect = 0.0
Identities = 875/875 (100%), Positives = 875/875 (100%)
Query: 1 MSGTKPDILWAPHHVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSDT 60
MSGTKPDILWAPHHVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSDT
Sbjct: 1 MSGTKPDILWAPHHVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSDT 60
Query: 61 PYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLA 120
PYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLA
Sbjct: 61 PYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLA 120
Query: 121 WNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYE 180
WNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYE
Sbjct: 121 WNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYE 180
Query: 181 LGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRV 240
LGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRV
Sbjct: 181 LGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRV 240
Query: 241 ASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQH 300
ASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQH
Sbjct: 241 ASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQH 300
Query: 301 TPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAW 360
TPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAW
Sbjct: 301 TPTPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAW 360
Query: 361 SPITSLMWACGRHLYECTEEENDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNED 420
SPITSLMWACGRHLYECTEEENDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNED
Sbjct: 361 SPITSLMWACGRHLYECTEEENDNSLEKDIATKMRLRALSRYGLDTEQVWRNHILAGNED 420
Query: 421 PQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQ 480
PQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQ
Sbjct: 421 PQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWSGLDKQ 480
Query: 481 SDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQI 540
SDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQI
Sbjct: 481 SDIQNLNEERILALQLCGWIKKGTDVDVGPFLNSLVQEGEWERAAAVALFNLDIRRAIQI 540
Query: 541 LNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSETG 600
LNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSETG
Sbjct: 541 LNEGASSEKGDLNLNVVAMALSGYTDEKNSLWREMCSTLRLQLNNPYLCVMFAFLTSETG 600
Query: 601 SYDGVLYENKVAVRDRVAFACKFLSDTQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVD 660
SYDGVLYENKVAVRDRVAFACKFLSDTQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVD
Sbjct: 601 SYDGVLYENKVAVRDRVAFACKFLSDTQLNRYIEKLTNEMKEAGNLEGILLTGLTKDGVD 660
Query: 661 LMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHR 720
LMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHR
Sbjct: 661 LMESYVDRTGDVQTASYCMLQGSPLDVLKDERVQYWIENYRNLLDAWRFWHKRAEFDIHR 720
Query: 721 SKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCPGCRK 780
SKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCPGCRK
Sbjct: 721 SKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCPGCRK 780
Query: 781 PLPRCALCLINMGTPVSSCPGGTKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHML 840
PLPRCALCLINMGTPVSSCPGGTKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHML
Sbjct: 781 PLPRCALCLINMGTPVSSCPGGTKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHAGHML 840
Query: 841 SWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP 875
SWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP
Sbjct: 841 SWFRDHAECPVSACTCKCMQLDTTGNLVPAETVQP 875
>gi|58331266 WD repeat domain 59 [Homo sapiens]
Length = 974
Score = 50.4 bits (119), Expect = 7e-06
Identities = 43/165 (26%), Positives = 65/165 (39%), Gaps = 52/165 (31%)
Query: 712 KRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISY---------------SCSAVPHQGR 756
+R + D ++ LDP++ Q F C I Y SC PH+G
Sbjct: 840 ERDQHDKNKRLLDPAN---TQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPDPHKG- 895
Query: 757 GFSQYGVSGSPTKSKV--TSCPGCRKPLPRCALCLINMGTPVSSCPGGTKSDEKVDLSKD 814
++GV S +S+V T C C+ +CA+C + + G+ +
Sbjct: 896 --IEFGVYCSHCRSEVRGTQCAICKGFTFQCAICHVAVR--------GSSN--------- 936
Query: 815 KKLAQFNNWFTWCHNCRHGGHAGHMLSWFRDHAECPVSACTCKCM 859
+C C HGGH HM+ WFR CP + C C C+
Sbjct: 937 -----------FCLTCGHGGHTSHMMEWFRTQEVCP-TGCGCHCL 969
Score = 42.0 bits (97), Expect = 0.002
Identities = 77/360 (21%), Positives = 150/360 (41%), Gaps = 46/360 (12%)
Query: 156 VPMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLPRDQKLLL-AGMHRNLAIFDLR 214
V + K K +GE TTL G L W + LL+ + + + I+D++
Sbjct: 85 VDLYKWKDGSGEVGTTLQ--------GHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIK 136
Query: 215 NTSQKMFVNTKAVQGVTVDPYFHDR---VASFYEGQVAIWDLRKFEKPVLTLTEQPKPLT 271
+T +K V AV G + + +A+ ++G V IWD RK V L +
Sbjct: 137 DT-RKPTVALSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIH 195
Query: 272 KVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPCDNYIASFAWH 331
+ W P +LAT ++D N ++ +D + + ++ PC + +
Sbjct: 196 GLDWHPDSEHILATSSQD-NSVKFWDYRQPRKYL-----------NILPCQVPVWKARYT 243
Query: 332 PTSQNRMIVVTPNRTMSDFTVFERISLAWSPITSLMWACGRHLYECTEEENDNSLEKDIA 391
P S + V+ P + + + +P+ + + L ++ + S + +
Sbjct: 244 PFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDYQLV 303
Query: 392 TKMRLRALSRYGLDT--EQVWRNHILAGNED-----PQLKSLWYTLHFMKQYTEDMDQK- 443
T R + L + +D+ +++ N IL G ++ L TLH TED D +
Sbjct: 304 TWSRDQTLRMWRVDSQMQRLCANDILDGVDEFIESISLLPEPEKTLH-----TEDTDHQH 358
Query: 444 --SPGNKGSLVYAGIKSIVK----SSLGMVESSRHNWSGLDKQSDIQNLNEERILALQLC 497
S G + +L +++++ LG+ ++ + +S ++ Q I+N+N E A + C
Sbjct: 359 TASHGEEEALKEDPPRNLLEERKSDQLGLPQTLQQEFSLINVQ--IRNVNVEMDAADRSC 416
>gi|14149987 WD repeat domain 24 [Homo sapiens]
Length = 790
Score = 49.7 bits (117), Expect = 1e-05
Identities = 49/194 (25%), Positives = 72/194 (37%), Gaps = 55/194 (28%)
Query: 660 DLMESYVDRTGDVQTA-SYCMLQGSPLDVLKDERVQ-YWIENYRNLLDAWRFWHKRAEFD 717
D++ Y ++ GDVQ A S ++ G + DE+ Q +W +Y +LL +R W+ E
Sbjct: 639 DMLHFYAEQ-GDVQMAVSVLIVLGERVRKDIDEQTQEHWYTSYIDLLQRFRLWNVSNEV- 696
Query: 718 IHRSKLDPSSKPLAQVFVSC-NFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCP 776
KL S VSC N ++ +CS H R P S+ C
Sbjct: 697 ---VKLSTSRA------VSCLNQASTTLHVNCS---HCKR----------PMSSRGWVCD 734
Query: 777 GCRKPLPRCALCLINMGTPVSSCPGGTKSDEKVDLSKDKKLAQFNNWFTWCHNCRHGGHA 836
C + CA+C + F WC C HGGH
Sbjct: 735 RCHRCASMCAVCHHVV----------------------------KGLFVWCQGCSHGGHL 766
Query: 837 GHMLSWFRDHAECP 850
H++ W + CP
Sbjct: 767 QHIMKWLEGSSHCP 780
Score = 41.6 bits (96), Expect = 0.003
Identities = 67/301 (22%), Positives = 112/301 (37%), Gaps = 69/301 (22%)
Query: 190 LCWLPRDQKLLLAGMHRN-LAIFDLRNTSQKMFVNTKAVQGVTV-DPYFHDR-----VAS 242
+C+ P + +LL+G + FDLR +K V+T + Q +V D F R ++
Sbjct: 126 VCFHPTEAHVLLSGSQDGFMKCFDLR---RKDSVSTFSGQSESVRDVQFSIRDYFTFAST 182
Query: 243 FYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTP 302
F G V +WD+R+ ++ T P+ W P G LAT RD +++++DM
Sbjct: 183 FENGNVQLWDIRRPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRD-KMVKVWDM---- 237
Query: 303 TPIGDETEPTIIERSVQPCDNYIASFAWHPTSQNRMIVVTPNRTMSDFTVFERISLAWSP 362
T C IAS A + W P
Sbjct: 238 ---------TTHRAKEMHCVQTIASVA---------------------------RVKWRP 261
Query: 363 ITSLMWACGRHLYECTEEENDNSLEKDIATKMRLRALSRYGLD--TEQVWR-----NHIL 415
C HL C+ + N D+ A+ D T WR + +L
Sbjct: 262 ------ECRHHLATCSMMVDHNIYVWDVRRPFVPAAMFEEHRDVTTGIAWRHPHDPSFLL 315
Query: 416 AGNEDPQLKSLWYTLHFMKQYTEDMDQKSPGNKGSLVYAGIKSIVKSSLGMVESSRHNWS 475
+G++D L H + ++ +++ +P ++ + K SL ES R ++
Sbjct: 316 SGSKDSSL-----CQHLFRDASQPVERANPEGLCYGLFGDLAFAAKESLVAAESGRKPYT 370
Query: 476 G 476
G
Sbjct: 371 G 371
Score = 34.3 bits (77), Expect = 0.52
Identities = 54/242 (22%), Positives = 96/242 (39%), Gaps = 29/242 (11%)
Query: 75 ECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGL- 133
E LLA NG VV +LG+ +K L +H R N + ++P +++ L +G
Sbjct: 87 ENLLATAATNGVVVTWNLGRPSRNKQDQLF-----TEHKRTVNKVCFHPTEAHVLLSGSQ 141
Query: 134 DKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTK----PLYELGQNDACLS 189
D F + D S ++ + V+ S + T + L+++ + D C
Sbjct: 142 DGFMKCFDLRRKDSVSTFSGQSESVRDVQFSIRDYFTFASTFENGNVQLWDIRRPDRCER 201
Query: 190 LC-----------WLPRDQK-LLLAGMHRNLAIFDLRNTSQKMF--VNTKA-VQGVTVDP 234
+ W P D+ L G + + ++D+ K V T A V V P
Sbjct: 202 MFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMTTHRAKEMHCVQTIASVARVKWRP 261
Query: 235 YFHDRVAS---FYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAW-CPTRTGLLATLTRDS 290
+A+ + + +WD+R+ P E T +AW P L + ++DS
Sbjct: 262 ECRHHLATCSMMVDHNIYVWDVRRPFVPAAMFEEHRDVTTGIAWRHPHDPSFLLSGSKDS 321
Query: 291 NI 292
++
Sbjct: 322 SL 323
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 48.1 bits (113), Expect = 3e-05
Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 21/194 (10%)
Query: 181 LGQNDACLSLCWLPRDQKLLLA-GMHRNLAIFDLRNTSQKM-FVNTKAVQGVTVDPYFHD 238
+G + L W P + + + ++ I+D+R K + T V+
Sbjct: 258 VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS 317
Query: 239 RVASFY-----EGQVAIWDLRKFEK--PVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSN 291
R F +G + IWDLR+F+ PV T + P+T V W P +G+ A D
Sbjct: 318 RREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQ 377
Query: 292 IIRLYDMQHTPTP-IGD-ETEPTIIERS-----VQPCDNYIASFAWHPTSQNRMIVVTPN 344
I + +D+ P GD E +P + + V + + WHP ++ +
Sbjct: 378 ITQ-WDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELHWHPQCPGLLV----S 432
Query: 345 RTMSDFTVFERISL 358
+S FT+F IS+
Sbjct: 433 TALSGFTIFRTISV 446
Score = 32.7 bits (73), Expect = 1.5
Identities = 43/205 (20%), Positives = 74/205 (36%), Gaps = 29/205 (14%)
Query: 7 DILWAPHHVDRFVVCDSELSLYHVESTVNSELKAGSLRLSEDSAATLLSINSDTPYMKCV 66
D+ W+P F C ++ S+ + +R + A L + + + +
Sbjct: 266 DLQWSPTENTVFASCSADASI-----------RIWDIRAAPSKACMLTTATAHDGDVNVI 314
Query: 67 AWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDS 126
+W E L G +G + + L Q FK +H ++ W+P DS
Sbjct: 315 SWSRR---EPFLLSGGDDGALKIWDLRQ-----FKSGSPVATFKQHVAPVTSVEWHPQDS 366
Query: 127 NWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYELGQNDA 186
AA AD + WD+ + P+ +E A + L V + EL +
Sbjct: 367 GVFAAS----GADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKE--- 419
Query: 187 CLSLCWLPRDQKLLLAGMHRNLAIF 211
L W P+ LL++ IF
Sbjct: 420 ---LHWHPQCPGLLVSTALSGFTIF 441
>gi|157739942 gemin 5 [Homo sapiens]
Length = 1508
Score = 45.8 bits (107), Expect = 2e-04
Identities = 33/114 (28%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 167 ETETTLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAI--FDLRNTSQKMFVNT 224
+ ET +VT+ + L Q+ +L W PR + L+++G + + + RN SQ +F+
Sbjct: 95 DVETKTVVTE--HALHQHTIS-TLHWSPRVKDLIVSGDEKGVVFCYWFNRNDSQHLFIEP 151
Query: 225 KAVQGVTVDPYFHDRVASFY-EGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCP 277
+ + +T P+ D VA Y +G V I D+ K + + L + +AWCP
Sbjct: 152 RTIFCLTCSPHHEDLVAIGYKDGIVVIIDISKKGEVIHRLRGHDDEIHSIAWCP 205
>gi|217330644 WD repeat domain 12 protein [Homo sapiens]
Length = 423
Score = 45.1 bits (105), Expect = 3e-04
Identities = 59/266 (22%), Positives = 106/266 (39%), Gaps = 26/266 (9%)
Query: 52 TLLSINSDTPYMKCVAWYLNYDPECLLAVGQANGRVVLTSLGQDHNSKFKDLIGKEFVPK 111
++++I T +K VAW CLL + ++L + N K K L
Sbjct: 132 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERN-KVKAL---HCCRG 187
Query: 112 HARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIV------PMEKVKLSA 165
HA +++A + + + + DK + IW D + P +K K
Sbjct: 188 HAGSVDSIAVDGSGTKFCSGSWDK-----MLKIWSTVPTDEEDEMEESTNRPRKKQK--- 239
Query: 166 GETETTLLVTKPLYEL-GQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQK-MFVN 223
TE L P+ L G +A S+ W ++ + A + ++D+ + S K
Sbjct: 240 --TEQLGLTRTPIVTLSGHMEAVSSVLWSDAEE-ICSASWDHTIRVWDVESGSLKSTLTG 296
Query: 224 TKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPV--LTLTEQPKPLTKVAWCPTRTG 281
K ++ P + + + +WD R + + L+LT +T V W PT
Sbjct: 297 NKVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQ 356
Query: 282 LLATLTRDSNIIRLYDMQHTPTPIGD 307
L + + D NI++L+D + P+ D
Sbjct: 357 QLISGSLD-NIVKLWDTRSCKAPLYD 381
Score = 33.1 bits (74), Expect = 1.2
Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 26/181 (14%)
Query: 133 LDKHRADFSVLIW----DICSKYTPDIVPMEKVKLSAGETETTLLVTKPLYELGQNDACL 188
L H S ++W +ICS + + V+ +G ++TL K C+
Sbjct: 253 LSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVE--SGSLKSTLTGNKVFN-------CI 303
Query: 189 SLCWLPRDQKLLLAGMHRNLAIFDLRN-----TSQKMFVNTKAVQGVTVDPYFHDRVAS- 242
S + P ++L R++ ++D R S + +T V V P ++ S
Sbjct: 304 S--YSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISG 361
Query: 243 FYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTP 302
+ V +WD R + P+ L + V W T TGLL + D+ +LY +++P
Sbjct: 362 SLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDW--TDTGLLLSGGADN---KLYSYRYSP 416
Query: 303 T 303
T
Sbjct: 417 T 417
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/255 (22%), Positives = 103/255 (40%), Gaps = 32/255 (12%)
Query: 112 HARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETET- 170
H ++ L+WNP S L + D H ++ +WDI + VP E + A T
Sbjct: 141 HQKEGYGLSWNPNLSGHLLSASDDH----TICLWDISA------VPKEGKVVDAKTIFTG 190
Query: 171 -TLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQG 229
T +V + L S+ DQKL++ N + S + +T V
Sbjct: 191 HTAVVEDVSWHLLHESLFGSVA---DDQKLMIWDTRSN----NTSKPSHSVDAHTAEVNC 243
Query: 230 VTVDPYFHDRVAS-FYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTR 288
++ +PY +A+ + VA+WDLR + + + + +V W P +LA+
Sbjct: 244 LSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 303
Query: 289 DSNIIRLYDMQHTPTPIGDETEPTIIERSVQPC-------DNYIASFAWHPTSQNRMIVV 341
D + ++D+ + IG+E P E I+ F+W+P + V
Sbjct: 304 DRR-LNVWDL----SKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSV 358
Query: 342 TPNRTMSDFTVFERI 356
+ + M + + E I
Sbjct: 359 SEDNIMQVWQMAENI 373
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/255 (22%), Positives = 103/255 (40%), Gaps = 32/255 (12%)
Query: 112 HARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETET- 170
H ++ L+WNP S L + D H ++ +WDI + VP E + A T
Sbjct: 175 HQKEGYGLSWNPNLSGHLLSASDDH----TICLWDISA------VPKEGKVVDAKTIFTG 224
Query: 171 -TLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQG 229
T +V + L S+ DQKL++ N + S + +T V
Sbjct: 225 HTAVVEDVSWHLLHESLFGSVA---DDQKLMIWDTRSN----NTSKPSHSVDAHTAEVNC 277
Query: 230 VTVDPYFHDRVAS-FYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTR 288
++ +PY +A+ + VA+WDLR + + + + +V W P +LA+
Sbjct: 278 LSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 337
Query: 289 DSNIIRLYDMQHTPTPIGDETEPTIIERSVQPC-------DNYIASFAWHPTSQNRMIVV 341
D + ++D+ + IG+E P E I+ F+W+P + V
Sbjct: 338 DRR-LNVWDL----SKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSV 392
Query: 342 TPNRTMSDFTVFERI 356
+ + M + + E I
Sbjct: 393 SEDNIMQVWQMAENI 407
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/255 (22%), Positives = 103/255 (40%), Gaps = 32/255 (12%)
Query: 112 HARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETET- 170
H ++ L+WNP S L + D H ++ +WDI + VP E + A T
Sbjct: 176 HQKEGYGLSWNPNLSGHLLSASDDH----TICLWDISA------VPKEGKVVDAKTIFTG 225
Query: 171 -TLLVTKPLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQG 229
T +V + L S+ DQKL++ N + S + +T V
Sbjct: 226 HTAVVEDVSWHLLHESLFGSVA---DDQKLMIWDTRSN----NTSKPSHSVDAHTAEVNC 278
Query: 230 VTVDPYFHDRVAS-FYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTR 288
++ +PY +A+ + VA+WDLR + + + + +V W P +LA+
Sbjct: 279 LSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNETILASSGT 338
Query: 289 DSNIIRLYDMQHTPTPIGDETEPTIIERSVQPC-------DNYIASFAWHPTSQNRMIVV 341
D + ++D+ + IG+E P E I+ F+W+P + V
Sbjct: 339 DRR-LNVWDL----SKIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSV 393
Query: 342 TPNRTMSDFTVFERI 356
+ + M + + E I
Sbjct: 394 SEDNIMQVWQMAENI 408
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 40.4 bits (93), Expect = 0.007
Identities = 57/259 (22%), Positives = 103/259 (39%), Gaps = 40/259 (15%)
Query: 112 HARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETT 171
H ++ L+WN S L + D H +V +WDI +AG E
Sbjct: 175 HQKEGYGLSWNSNLSGHLLSASDDH----TVCLWDI----------------NAGPKEGK 214
Query: 172 LLVTKPLYELGQNDACLSLCWLPRDQKLL-LAGMHRNLAIFDLR-NTSQK----MFVNTK 225
++ K ++ G + + W + L + L I+D R NT+ K + +T
Sbjct: 215 IVDAKAIFT-GHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTA 273
Query: 226 AVQGVTVDPYFHDRVAS-FYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLA 284
V ++ +PY +A+ + VA+WDLR + + T + +V W P +LA
Sbjct: 274 EVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILA 333
Query: 285 TLTRDSNIIRLYDMQHTPTPIGDETEPTIIERSVQPC-------DNYIASFAWHPTSQNR 337
+ D + ++D+ + IG+E E I+ F+W+P
Sbjct: 334 SSGTDRR-LNVWDL----SKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWV 388
Query: 338 MIVVTPNRTMSDFTVFERI 356
+ V+ + M + + E I
Sbjct: 389 ICSVSEDNIMQIWQMAENI 407
>gi|14149696 SEC31 homolog B [Homo sapiens]
Length = 1179
Score = 39.3 bits (90), Expect = 0.016
Identities = 50/228 (21%), Positives = 84/228 (36%), Gaps = 47/228 (20%)
Query: 81 GQANGRVVLTSLGQDHNSKFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADF 140
G NG ++L ++ +S + +I ++ KH L NP N LA+G +D
Sbjct: 91 GGDNGMLILYNVTHILSSGKEPVIAQK--QKHTGAVRALDLNPFQGNLLASGA----SDS 144
Query: 141 SVLIWDICSKYTPDIV------PMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLP 194
+ IWD+ + P + P E +K +L W
Sbjct: 145 EIFIWDLNNLNVPMTLGSKSQQPPEDIK--------------------------ALSWNR 178
Query: 195 RDQKLLLAGMHRNLAI-FDLRNTSQKMFV----NTKAVQGVTVDPYFHDRVASFYEGQ-- 247
+ Q +L + A+ +DLR + V N G+ P ++ E
Sbjct: 179 QAQHILSSAHPSGKAVVWDLRKNEPIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRL 238
Query: 248 --VAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNII 293
+ +WDLR P+ L + + V+W LL T +DS I+
Sbjct: 239 PVIQLWDLRFASSPLKVLESHSRGILSVSWSQADAELLLTSAKDSQIL 286
Score = 32.3 bits (72), Expect = 2.0
Identities = 28/124 (22%), Positives = 62/124 (50%), Gaps = 13/124 (10%)
Query: 194 PRDQKLLLAGMHRN-LAIFDLRNTSQKMFVNTKA------VQGVTVDPYFHDRVASFY-E 245
P LL +G + + I+DL N + M + +K+ ++ ++ + ++S +
Sbjct: 131 PFQGNLLASGASDSEIFIWDLNNLNVPMTLGSKSQQPPEDIKALSWNRQAQHILSSAHPS 190
Query: 246 GQVAIWDLRKFEKPVLTLTEQPKPL--TKVAWCPTRTGLLATLTRDSN--IIRLYDMQHT 301
G+ +WDLRK E P++ +++ + + +AW P L + D +I+L+D++
Sbjct: 191 GKAVVWDLRKNE-PIIKVSDHSNRMHCSGLAWHPDIATQLVLCSEDDRLPVIQLWDLRFA 249
Query: 302 PTPI 305
+P+
Sbjct: 250 SSPL 253
>gi|239743654 PREDICTED: similar to block of proliferation 1 [Homo
sapiens]
Length = 668
Score = 37.4 bits (85), Expect = 0.061
Identities = 68/306 (22%), Positives = 116/306 (37%), Gaps = 24/306 (7%)
Query: 41 GSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPE-CLLAVGQANGRVVLT-SLGQDHNS 98
GSLRL E + A + +K VAW N P CL+A + ++L +LG +
Sbjct: 357 GSLRLWEVATARCVRTVPVGGVVKSVAW--NPSPAVCLVAAAVEDSVLLLNPALGDRLVA 414
Query: 99 KFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDK---HRADFSVLIWDICSKYTPDI 155
D + FVP W GL H + + W Y +
Sbjct: 415 GSTDQLLSAFVPPEEPPLQPARWLEASEEERQVGLRLRICHGKPVTQVTWHGRGDYLAVV 474
Query: 156 VPMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLPR-----DQKLLLAGMHRNLAI 210
+ A + T +L+ + Q+ S + R + LL R++ +
Sbjct: 475 L--------ATQGHTQVLIHQLSRRRSQSPFRRSHGQVQRVAFHPARPFLLVASQRSVRL 526
Query: 211 FDL--RNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPK 268
+ L + ++K+ N K V + V P + + Y+ ++ +DL KP L K
Sbjct: 527 YHLLRQELTKKLMPNCKWVSSLAVHPAGDNVICGSYDSKLVWFDLDLSTKPYRMLRHHKK 586
Query: 269 PLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPT-IIERSVQPCDNYIAS 327
L VA+ P R L A+ + D ++I + M + P +++ V D +
Sbjct: 587 ALRAVAFHP-RYPLFASGSDDGSVIVCHGMVYNDLLQNPLLVPVKVLKGHVLTRDLGVLD 645
Query: 328 FAWHPT 333
+HPT
Sbjct: 646 VIFHPT 651
>gi|21327667 block of proliferation 1 [Homo sapiens]
Length = 746
Score = 37.4 bits (85), Expect = 0.061
Identities = 68/306 (22%), Positives = 116/306 (37%), Gaps = 24/306 (7%)
Query: 41 GSLRLSEDSAATLLSINSDTPYMKCVAWYLNYDPE-CLLAVGQANGRVVLT-SLGQDHNS 98
GSLRL E + A + +K VAW N P CL+A + ++L +LG +
Sbjct: 435 GSLRLWEVATARCVRTVPVGGVVKSVAW--NPSPAVCLVAAAVEDSVLLLNPALGDRLVA 492
Query: 99 KFKDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDK---HRADFSVLIWDICSKYTPDI 155
D + FVP W GL H + + W Y +
Sbjct: 493 GSTDQLLSAFVPPEEPPLQPARWLEASEEERQVGLRLRICHGKPVTQVTWHGRGDYLAVV 552
Query: 156 VPMEKVKLSAGETETTLLVTKPLYELGQNDACLSLCWLPR-----DQKLLLAGMHRNLAI 210
+ A + T +L+ + Q+ S + R + LL R++ +
Sbjct: 553 L--------ATQGHTQVLIHQLSRRRSQSPFRRSHGQVQRVAFHPARPFLLVASQRSVRL 604
Query: 211 FDL--RNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPK 268
+ L + ++K+ N K V + V P + + Y+ ++ +DL KP L K
Sbjct: 605 YHLLRQELTKKLMPNCKWVSSLAVHPAGDNVICGSYDSKLVWFDLDLSTKPYRMLRHHKK 664
Query: 269 PLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPT-IIERSVQPCDNYIAS 327
L VA+ P R L A+ + D ++I + M + P +++ V D +
Sbjct: 665 ALRAVAFHP-RYPLFASGSDDGSVIVCHGMVYNDLLQNPLLVPVKVLKGHVLTRDLGVLD 723
Query: 328 FAWHPT 333
+HPT
Sbjct: 724 VIFHPT 729
>gi|109627650 coronin 6 [Homo sapiens]
Length = 472
Score = 37.0 bits (84), Expect = 0.080
Identities = 20/85 (23%), Positives = 43/85 (50%), Gaps = 5/85 (5%)
Query: 255 KFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIGDETEPTII 314
+ +K +T P+ + WCP ++A+ + D+ I+ + TP+ + TEP I
Sbjct: 69 RVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDY--TPMRNITEPII- 125
Query: 315 ERSVQPCDNYIASFAWHPTSQNRMI 339
+++ + +WHPT++N ++
Sbjct: 126 --TLEGHSKRVGILSWHPTARNVLL 148
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 35.4 bits (80), Expect = 0.23
Identities = 48/191 (25%), Positives = 77/191 (40%), Gaps = 38/191 (19%)
Query: 101 KDLIGKEFVPKHARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEK 160
KDL+G H N + ++ WL +G D R VL+W ME+
Sbjct: 47 KDLLG------HFGCVNAIEFSNNGGQWLVSGGDDRR----VLLWH-----------MEQ 85
Query: 161 VKLSAGETETTLLVTKPLYELGQNDACL-SLCWLPRDQKLLLAGMHRNLAIFDLRNTSQ- 218
S KP+ G++ + + L + + K+ G + + D+ ++
Sbjct: 86 AIHSR---------VKPIQLKGEHHSNIFCLAFNSGNTKVFSGGNDEQVILHDVESSETL 136
Query: 219 KMFVNTKAVQGVTVDPYFHDRVASFYE-GQVAIWDLRKFEKP---VLTLTEQPKPLTKVA 274
+F + AV G++V P + AS + G+V IWD+R E P L P V
Sbjct: 137 DVFAHEDAVYGLSVSPVNDNIFASSSDDGRVLIWDIR--ESPHGEPFCLANYPSAFHSVM 194
Query: 275 WCPTRTGLLAT 285
+ P LLAT
Sbjct: 195 FNPVEPRLLAT 205
>gi|59938780 WD repeat domain 31 isoform 1 [Homo sapiens]
Length = 367
Score = 35.4 bits (80), Expect = 0.23
Identities = 41/206 (19%), Positives = 78/206 (37%), Gaps = 31/206 (15%)
Query: 112 HARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPD-------------IVPM 158
H + +A P S + +A D+ V++WD+ P V
Sbjct: 102 HEHEITKVACIPKSSQFFSASRDR-----MVMMWDLHGSSQPRQQLCGHAMVVTGLAVSP 156
Query: 159 EKVKLSAGETETTLLVTKPLYELGQNDACLS------LCWLPRDQKLLLAGMHRNLAIFD 212
+ +L G + TLL+ + A +S LCW+PR+ +L + L ++D
Sbjct: 157 DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWD 216
Query: 213 LRNTS-QKMFVNTKAVQ---GVTVDPYFHDRVASFYEG---QVAIWDLRKFEKPVLTLTE 265
R MF + +Q V+VD + ++ + G + +WDLR+ +
Sbjct: 217 SRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKG 276
Query: 266 QPKPLTKVAWCPTRTGLLATLTRDSN 291
+ + + P L+ + S+
Sbjct: 277 HFQTVASCVFLPRALALMPLIATSSH 302
>gi|21687048 WD repeat domain 31 isoform 3 [Homo sapiens]
Length = 366
Score = 35.4 bits (80), Expect = 0.23
Identities = 41/206 (19%), Positives = 78/206 (37%), Gaps = 31/206 (15%)
Query: 112 HARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPD-------------IVPM 158
H + +A P S + +A D+ V++WD+ P V
Sbjct: 101 HEHEITKVACIPKSSQFFSASRDR-----MVMMWDLHGSSQPRQQLCGHAMVVTGLAVSP 155
Query: 159 EKVKLSAGETETTLLVTKPLYELGQNDACLS------LCWLPRDQKLLLAGMHRNLAIFD 212
+ +L G + TLL+ + A +S LCW+PR+ +L + L ++D
Sbjct: 156 DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWD 215
Query: 213 LRNTS-QKMFVNTKAVQ---GVTVDPYFHDRVASFYEG---QVAIWDLRKFEKPVLTLTE 265
R MF + +Q V+VD + ++ + G + +WDLR+ +
Sbjct: 216 SRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKG 275
Query: 266 QPKPLTKVAWCPTRTGLLATLTRDSN 291
+ + + P L+ + S+
Sbjct: 276 HFQTVASCVFLPRALALMPLIATSSH 301
>gi|119120894 Dmx-like 2 [Homo sapiens]
Length = 3036
Score = 34.3 bits (77), Expect = 0.52
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 190 LCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNT-----KAVQGVTVDPYFHDRVASFY 244
L + P+ Q L+ G ++ IFD+R Q+ ++T A++ + +DPY
Sbjct: 2906 LQYAPKQQLLISGGRKGHVCIFDIR---QRQLIHTFQAHDSAIKALALDPYEEYFTTGSA 2962
Query: 245 EGQVAIWDL 253
EG + +W L
Sbjct: 2963 EGNIKVWRL 2971
>gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Homo
sapiens]
Length = 1151
Score = 34.3 bits (77), Expect = 0.52
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 14/102 (13%)
Query: 194 PRDQKLLLAGMHRN-LAIFDLRNT-SQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIW 251
P D+ LL G + ++DL++ + + +A+ V + S +G + IW
Sbjct: 205 PMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIW 264
Query: 252 DLRKFEKPVLTLT------------EQPKPLTKVAWCPTRTG 281
++R KPV T+T E KP+ KV + TR+G
Sbjct: 265 NVRSPAKPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSG 306
>gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Homo
sapiens]
Length = 1115
Score = 34.3 bits (77), Expect = 0.52
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 14/102 (13%)
Query: 194 PRDQKLLLAGMHRN-LAIFDLRNT-SQKMFVNTKAVQGVTVDPYFHDRVASFYEGQVAIW 251
P D+ LL G + ++DL++ + + +A+ V + S +G + IW
Sbjct: 205 PMDEGKLLIGFESGTVVLWDLKSKKADYRYTYDEAIHSVAWHHEGKQFICSHSDGTLTIW 264
Query: 252 DLRKFEKPVLTLT------------EQPKPLTKVAWCPTRTG 281
++R KPV T+T E KP+ KV + TR+G
Sbjct: 265 NVRSPAKPVQTITPHGKQLKDGKKPEPCKPILKVEFKTTRSG 306
>gi|229892270 WD repeats and SOF1 domain containing [Homo sapiens]
Length = 597
Score = 33.9 bits (76), Expect = 0.68
Identities = 24/72 (33%), Positives = 39/72 (54%), Gaps = 3/72 (4%)
Query: 232 VDPYFHDRVASFYEGQVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSN 291
+D ++ + V + QV IWD ++ P+ ++T ++ V + P T LL + D N
Sbjct: 314 IDHHWKEAVFATCGQQVDIWDEQR-TNPICSMTWGFDSISSVKFNPIETFLLGSCASDRN 372
Query: 292 IIRLYDM-QHTP 302
I+ LYDM Q TP
Sbjct: 373 IV-LYDMRQATP 383
Score = 30.8 bits (68), Expect = 5.7
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 31/154 (20%)
Query: 117 NTLAWNPLDSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGETETTLLVTK 176
NT+ WNP+++ A D+++ +D+ + TP +V M+ V
Sbjct: 394 NTICWNPMEAFIFTAA----NEDYNLYTFDMRALDTPVMVHMDHV--------------- 434
Query: 177 PLYELGQNDACLSLCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYF 236
A L + + P ++ + A +++ IF + + + +TK +Q V +
Sbjct: 435 --------SAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVYHTKRMQHVICVKWT 486
Query: 237 HDR---VASFYEGQVAIWDLRKFEK-PVLTLTEQ 266
D + E + +W EK VLT E+
Sbjct: 487 SDSKYIMCGSDEMNIRLWKANASEKLGVLTSREK 520
>gi|78482617 general transcription factor IIIC, polypeptide 2, beta
110kDa [Homo sapiens]
Length = 911
Score = 33.5 bits (75), Expect = 0.88
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 33/139 (23%)
Query: 110 PKHARQCNTLAWNPL-DSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGET 168
P QC +LAW P LAAG + V+ W++ P P+++++LS G
Sbjct: 551 PSECGQCLSLAWMPTRPHQHLAAGY----YNGMVVFWNL-----PTNSPLQRIRLSDGSL 601
Query: 169 ETTLLVTKPLYE----LGQNDACLSLCWLPRDQKLLL-AGMHRNLAIFDLRN-----TSQ 218
+ LY L + A +L W + L+ AG R + +DLR S
Sbjct: 602 K--------LYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSI 653
Query: 219 KMFVNTKAV-----QGVTV 232
K F++T+ GVTV
Sbjct: 654 KRFLSTELAWLLPYNGVTV 672
>gi|4504205 general transcription factor IIIC, polypeptide 2, beta
110kDa [Homo sapiens]
Length = 911
Score = 33.5 bits (75), Expect = 0.88
Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 33/139 (23%)
Query: 110 PKHARQCNTLAWNPL-DSNWLAAGLDKHRADFSVLIWDICSKYTPDIVPMEKVKLSAGET 168
P QC +LAW P LAAG + V+ W++ P P+++++LS G
Sbjct: 551 PSECGQCLSLAWMPTRPHQHLAAGY----YNGMVVFWNL-----PTNSPLQRIRLSDGSL 601
Query: 169 ETTLLVTKPLYE----LGQNDACLSLCWLPRDQKLLL-AGMHRNLAIFDLRN-----TSQ 218
+ LY L + A +L W + L+ AG R + +DLR S
Sbjct: 602 K--------LYPFQCFLAHDQAVRTLQWCKANSHFLVSAGSDRKIKFWDLRRPYEPINSI 653
Query: 219 KMFVNTKAV-----QGVTV 232
K F++T+ GVTV
Sbjct: 654 KRFLSTELAWLLPYNGVTV 672
>gi|4507703 tumor suppressing subtransferable candidate 1 [Homo
sapiens]
Length = 387
Score = 33.5 bits (75), Expect = 0.88
Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 10/98 (10%)
Query: 247 QVAIWDLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPTPIG 306
+V WD R +PV TL E + V + + L+ T + DS +I + + P G
Sbjct: 252 KVKFWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFG 311
Query: 307 ---------DETEPTIIERSVQPC-DNYIASFAWHPTS 334
D+ + E+S +P DN IA++ H S
Sbjct: 312 HLVDDDDISDQEDHRSEEKSKEPLQDNVIATYEEHEDS 349
>gi|148528998 Dmx-like 1 [Homo sapiens]
Length = 3027
Score = 33.5 bits (75), Expect = 0.88
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 2/69 (2%)
Query: 190 LCWLPRDQKLLLAGMHRNLAIFDLRNTSQKMFVNT--KAVQGVTVDPYFHDRVASFYEGQ 247
L + P+ Q L+ G +FDL Q+ + V+ V VDP V EG
Sbjct: 2892 LAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGN 2951
Query: 248 VAIWDLRKF 256
+ IW L F
Sbjct: 2952 IKIWSLSTF 2960
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 32.7 bits (73), Expect = 1.5
Identities = 39/154 (25%), Positives = 66/154 (42%), Gaps = 24/154 (15%)
Query: 7 DILWAPHHVDRFVV---CDSELSLYHVESTVNSELKAGSLRLSEDSAATLL---SINSDT 60
DI++ P + R C S L H E+ ++ L+ S T + ++++T
Sbjct: 89 DIIYQPQAIFRVRAVTRCTSSLE-GHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTET 147
Query: 61 PYMKCVA---WYLN--YDPECL-LAVGQANGRVVL--TSLGQDHNSKFKDLIGKEFVPKH 112
P+ C W L+ + P+ LA G NG+++L S G+ +G+ H
Sbjct: 148 PHFTCKGHRHWVLSISWSPDGRKLASGCKNGQILLWDPSTGKQ--------VGRTLAG-H 198
Query: 113 ARQCNTLAWNPLDSNWLAAGLDKHRADFSVLIWD 146
++ L+W PL +N + D SV IWD
Sbjct: 199 SKWITGLSWEPLHANPECRYVASSSKDGSVRIWD 232
>gi|66267730 WD repeat domain 34 [Homo sapiens]
Length = 536
Score = 32.7 bits (73), Expect = 1.5
Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 7/78 (8%)
Query: 207 NLAIFDLRNTSQKMFVNT-KAVQGVTVDPYFHDRVAS-FYEGQVAIWDLRKFEKPVLTLT 264
NL DLR V AV + P VA Y G+V +WDL + E P+L T
Sbjct: 199 NLDRRDLRPQQPSAVVEVPSAVLCLAFHPTQPSHVAGGLYSGEVLVWDLSRLEDPLLWRT 258
Query: 265 -----EQPKPLTKVAWCP 277
P+++V W P
Sbjct: 259 GLTDDTHTDPVSQVVWLP 276
>gi|108936958 WD-repeat protein [Homo sapiens]
Length = 342
Score = 32.3 bits (72), Expect = 2.0
Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 11/117 (9%)
Query: 178 LYELGQNDACLSLCWLPRDQKLL--LAGMHRNLAIFDLR---NTSQKMFVNTKAVQGVTV 232
+YE Q+ L LCW +D L +A + I D+R ++ + V G+
Sbjct: 215 IYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCTPVARLNNHRACVNGIAW 274
Query: 233 DPYFHDRVASFYEG-QVAIWDL----RKFEKPVLTLTEQPKPLTKVAWCPTRTGLLA 284
P+ + + + Q IWD+ R E P+L T + + + V W T+ +A
Sbjct: 275 APHSSCHICTAADDHQALIWDIQQMPRAIEDPILAYTAEGE-INNVQWASTQPDWIA 330
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/62 (27%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Query: 245 EGQVAIWDLRKFEKPVLTLTE-QPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQHTPT 303
+G V ++DLR E + + Q PL ++ W LAT+ D + + D++ T
Sbjct: 198 DGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEVVILDVRVPCT 257
Query: 304 PI 305
P+
Sbjct: 258 PV 259
>gi|84626578 G protein beta subunit-like [Homo sapiens]
Length = 326
Score = 32.3 bits (72), Expect = 2.0
Identities = 29/138 (21%), Positives = 58/138 (42%), Gaps = 9/138 (6%)
Query: 196 DQKLLLAGMHRNLAIFDLRNTSQKMFVNTKAVQGVTVDPYFHDRVASFYEG----QVAIW 251
D+ ++ A ++++ ++DL + + ++ V FH+ Y G IW
Sbjct: 53 DRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIW 112
Query: 252 DLRKFEKPVLTLTEQPKPLTKVAWCPTRTGLLATLTRDSNIIRLYDMQ--HTPTPIGDET 309
DLR + + P+ V P + L+ + S I ++D++ H I E
Sbjct: 113 DLRSRNLQCQRIFQVNAPINCVCLHPNQAELI--VGDQSGAIHIWDLKTDHNEQLI-PEP 169
Query: 310 EPTIIERSVQPCDNYIAS 327
E +I + P +Y+A+
Sbjct: 170 EVSITSAHIDPDASYMAA 187
>gi|117956407 zinc finger protein 568 [Homo sapiens]
Length = 644
Score = 32.3 bits (72), Expect = 2.0
Identities = 26/114 (22%), Positives = 43/114 (37%), Gaps = 24/114 (21%)
Query: 705 DAWRFWHKRAEFDIHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQ---------- 754
D W+ + +++ I ++ KP C CGKS S + + H+
Sbjct: 310 DCWKAFSQKSNL-IEHERIHTGEKPY-----ECKECGKSFSQKQNLIEHEKIHTGEKPYA 363
Query: 755 ----GRGFSQYGV----SGSPTKSKVTSCPGCRKPLPRCALCLINMGTPVSSCP 800
GR FS+ S T K C C K +C++ +I+M + P
Sbjct: 364 CNECGRAFSRMSSVTLHMRSHTGEKPYKCNKCGKAFSQCSVFIIHMRSHTGEKP 417
Score = 30.0 bits (66), Expect = 9.8
Identities = 22/83 (26%), Positives = 30/83 (36%), Gaps = 15/83 (18%)
Query: 718 IHRSKLDPSSKPLAQVFVSCNFCGKSISYSCSAVPHQGRGFSQYGVSGSPTKSKVTSCPG 777
+ K+ KP CN CGK+ S S H S T K C
Sbjct: 546 LEHEKIHTGEKPF-----KCNECGKAFSRISSLTLHVR----------SHTGEKPYECNK 590
Query: 778 CRKPLPRCALCLINMGTPVSSCP 800
C K +C+L +I+M + P
Sbjct: 591 CGKAFSQCSLLIIHMRSHTGEKP 613
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,190,948
Number of Sequences: 37866
Number of extensions: 1556163
Number of successful extensions: 5471
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 5334
Number of HSP's gapped (non-prelim): 183
length of query: 875
length of database: 18,247,518
effective HSP length: 111
effective length of query: 764
effective length of database: 14,044,392
effective search space: 10729915488
effective search space used: 10729915488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.