Guide to the Human Genome
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Search of human proteins with 109148531

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109148531 coiled-coil domain containing 98 [Homo sapiens]
         (409 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109148531 coiled-coil domain containing 98 [Homo sapiens]          816   0.0  
gi|148529023 hypothetical protein LOC23172 [Homo sapiens]             210   2e-54
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    35   0.094
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    35   0.094
gi|7662230 ring finger protein 40 [Homo sapiens]                       35   0.094
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo...    35   0.094
gi|46249351 homer 2 isoform 2 [Homo sapiens]                           35   0.12 
gi|46249349 homer 2 isoform 1 [Homo sapiens]                           35   0.12 
gi|110349797 homer 2 isoform 4 [Homo sapiens]                          35   0.12 
gi|110349794 homer 2 isoform 3 [Homo sapiens]                          35   0.12 
gi|10190716 spindle pole body component 25 [Homo sapiens]              35   0.12 
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       35   0.16 
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       35   0.16 
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        35   0.16 
gi|21735548 centrosomal protein 2 [Homo sapiens]                       34   0.21 
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              34   0.21 
gi|63999048 syntaxin binding protein 4 [Homo sapiens]                  34   0.21 
gi|41872583 Rho-associated, coiled-coil containing protein kinas...    34   0.27 
gi|4758646 kinesin family member 3B [Homo sapiens]                     33   0.36 
gi|187761324 shootin1 isoform a [Homo sapiens]                         33   0.36 
gi|50511340 shootin1 isoform b [Homo sapiens]                          33   0.36 
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s...    33   0.36 
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]       33   0.36 
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    33   0.47 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    33   0.47 
gi|55770834 centromere protein F [Homo sapiens]                        33   0.47 
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]    33   0.47 
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]    33   0.47 
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]    33   0.47 
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s...    33   0.47 

>gi|109148531 coiled-coil domain containing 98 [Homo sapiens]
          Length = 409

 Score =  816 bits (2109), Expect = 0.0
 Identities = 409/409 (100%), Positives = 409/409 (100%)

Query: 1   MEGESTSAVLSGFVLGALAFQHLNTDSDTEGFLLGEVKGEAKNSITDSQMDDVEVVYTID 60
           MEGESTSAVLSGFVLGALAFQHLNTDSDTEGFLLGEVKGEAKNSITDSQMDDVEVVYTID
Sbjct: 1   MEGESTSAVLSGFVLGALAFQHLNTDSDTEGFLLGEVKGEAKNSITDSQMDDVEVVYTID 60

Query: 61  IQKYIPCYQLFSFYNSSGEVNEQALKKILSNVKKNVVGWYKFRRHSDQIMTFRERLLHKN 120
           IQKYIPCYQLFSFYNSSGEVNEQALKKILSNVKKNVVGWYKFRRHSDQIMTFRERLLHKN
Sbjct: 61  IQKYIPCYQLFSFYNSSGEVNEQALKKILSNVKKNVVGWYKFRRHSDQIMTFRERLLHKN 120

Query: 121 LQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGYK 180
           LQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGYK
Sbjct: 121 LQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGYK 180

Query: 181 TVSGSCMSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAV 240
           TVSGSCMSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAV
Sbjct: 181 TVSGSCMSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAV 240

Query: 241 DKLVKDVNRLKREIEKRRGAQIQAAREKNIQKDPQENIFLCQALRTFFPNSEFLHSCVMS 300
           DKLVKDVNRLKREIEKRRGAQIQAAREKNIQKDPQENIFLCQALRTFFPNSEFLHSCVMS
Sbjct: 241 DKLVKDVNRLKREIEKRRGAQIQAAREKNIQKDPQENIFLCQALRTFFPNSEFLHSCVMS 300

Query: 301 LKNRHVSKSSCNYNHHLDVVDNLTLMVEHTDIPEASPASTPQIIKHKALDLDDRWQFKRS 360
           LKNRHVSKSSCNYNHHLDVVDNLTLMVEHTDIPEASPASTPQIIKHKALDLDDRWQFKRS
Sbjct: 301 LKNRHVSKSSCNYNHHLDVVDNLTLMVEHTDIPEASPASTPQIIKHKALDLDDRWQFKRS 360

Query: 361 RLLDTQDKRSKADTGSSNQDKASKMSSPETDEEIEKMKGFGEYSRSPTF 409
           RLLDTQDKRSKADTGSSNQDKASKMSSPETDEEIEKMKGFGEYSRSPTF
Sbjct: 361 RLLDTQDKRSKADTGSSNQDKASKMSSPETDEEIEKMKGFGEYSRSPTF 409


>gi|148529023 hypothetical protein LOC23172 [Homo sapiens]
          Length = 415

 Score =  210 bits (534), Expect = 2e-54
 Identities = 103/260 (39%), Positives = 171/260 (65%), Gaps = 1/260 (0%)

Query: 7   SAVLSGFVLGALAFQHLNTDSDTEGFLLGEVKGEAKNSITDSQMDDVEVVYTIDIQKYIP 66
           +A +SG+   A+ F   N+++D EGFLLGEV+ E   SI+DSQ+ + E +  I+I  + P
Sbjct: 2   AASISGYTFSAVCFHSANSNADHEGFLLGEVRQEETFSISDSQISNTEFLQVIEIHNHQP 61

Query: 67  CYQLFSFYNSSGEVNEQALKKILSNVKKNVVGWYKFRRHSDQIMTFRERLLHKNLQEHFS 126
           C +LFSFY+ + +VNE++L +IL + +K V+GWY+FRR++ Q M++RE++LHK L     
Sbjct: 62  CSKLFSFYDYASKVNEESLDRILKDRRKKVIGWYRFRRNTQQQMSYREQVLHKQLTRILG 121

Query: 127 NQDLVFLLLTPSIITESCSTHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGYKTVSGSC 186
             DLVFLL +  I T + STH LE+ L++P +    R+ L + NLG + Q  YK  S   
Sbjct: 122 VPDLVFLLFS-FISTANNSTHALEYVLFRPNRRYNQRISLAIPNLGNTSQQEYKVSSVPN 180

Query: 187 MSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKD 246
            S  +++ ++ H + FF++DG +K++  I ++Y +LQE+++++C  VE SE+ V+    +
Sbjct: 181 TSQSYAKVIKEHGTDFFDKDGVMKDIRAIYQVYNALQEKVQAVCADVEKSERVVESCQAE 240

Query: 247 VNRLKREIEKRRGAQIQAAR 266
           VN+L+R+I +R+  + Q  R
Sbjct: 241 VNKLRRQITQRKNEKEQERR 260


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 35.4 bits (80), Expect = 0.094
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 204 EEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIE--KRRGAQ 261
           E +  L  + K NE+       LK  C+K+E  EQ   +L ++  +LK+ ++  K    Q
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ 688

Query: 262 IQAAREKNIQKDPQENIFL 280
           +++  ++N Q D +EN+ L
Sbjct: 689 LESLEKENSQLD-EENLEL 706


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 35.4 bits (80), Expect = 0.094
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 3/79 (3%)

Query: 204 EEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIE--KRRGAQ 261
           E +  L  + K NE+       LK  C+K+E  EQ   +L ++  +LK+ ++  K    Q
Sbjct: 629 ELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ 688

Query: 262 IQAAREKNIQKDPQENIFL 280
           +++  ++N Q D +EN+ L
Sbjct: 689 LESLEKENSQLD-EENLEL 706


>gi|7662230 ring finger protein 40 [Homo sapiens]
          Length = 1001

 Score = 35.4 bits (80), Expect = 0.094
 Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 8/90 (8%)

Query: 188 STGFSRAVQTHSSKFFEEDGSLKEV--------HKINEMYASLQEELKSICKKVEDSEQA 239
           S   S A Q H+ +   E+  L+++        H+I+  Y+ LQ+++ S   KV + E  
Sbjct: 219 SEPLSEAAQAHTRELGRENRRLQDLATQLQEKHHRISLEYSELQDKVTSAETKVLEMETT 278

Query: 240 VDKLVKDVNRLKREIEKRRGAQIQAAREKN 269
           V+ L  D+ +L++  +K      +A  + N
Sbjct: 279 VEDLQWDIEKLRKREQKLNKHLAEALEQLN 308


>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
           sapiens]
          Length = 805

 Score = 35.4 bits (80), Expect = 0.094
 Identities = 47/215 (21%), Positives = 82/215 (38%), Gaps = 31/215 (14%)

Query: 62  QKYIPCYQLFSFYNSSGEVNEQAL--KKILSNVKKNVVGWYKFRRHSDQIMTFRERLLHK 119
           Q Y P YQ FS + S  ++ E  L  K+I+ + +K  +     R   +++     R  H 
Sbjct: 348 QSYSPGYQDFSKWESMLKIKEGLLRQKEIVIDRQKQQITHLHERIRDNEL-----RAQHA 402

Query: 120 NLQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGY 179
            L  + + +D     L P     S  T   E S+   Q+G F +                
Sbjct: 403 MLGHYVNCEDSYVASLQPQYENTSLQTPFSEESVSHSQQGEFEQ---------------- 446

Query: 180 KTVSGSCMSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQA 239
           K  S        +  ++   S F EE   L+E  K  + Y S    LK  C+K  +  + 
Sbjct: 447 KLASTEKEVLQLNEFLKQRLSLFSEEKKKLEEKLKTRDRYIS---SLKKKCQKESEQNKE 503

Query: 240 VDKLVKDVNRLKREIE-----KRRGAQIQAAREKN 269
             + ++ + +   ++      + +  Q+Q   EKN
Sbjct: 504 KQRRIETLEKYLADLPTLDDVQSQSLQLQILEEKN 538


>gi|46249351 homer 2 isoform 2 [Homo sapiens]
          Length = 354

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 188 STGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDV 247
           +T   R ++   ++  E++  LK++ K +E+   L  E + + +K+E +E+    L   V
Sbjct: 246 NTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKV 305

Query: 248 NRLKREIEKRRGAQ 261
             LK +IE+ +  Q
Sbjct: 306 RSLKTDIEESKYRQ 319


>gi|46249349 homer 2 isoform 1 [Homo sapiens]
          Length = 343

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 188 STGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDV 247
           +T   R ++   ++  E++  LK++ K +E+   L  E + + +K+E +E+    L   V
Sbjct: 235 NTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKV 294

Query: 248 NRLKREIEKRRGAQ 261
             LK +IE+ +  Q
Sbjct: 295 RSLKTDIEESKYRQ 308


>gi|110349797 homer 2 isoform 4 [Homo sapiens]
          Length = 299

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 188 STGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDV 247
           +T   R ++   ++  E++  LK++ K +E+   L  E + + +K+E +E+    L   V
Sbjct: 191 NTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKV 250

Query: 248 NRLKREIEKRRGAQ 261
             LK +IE+ +  Q
Sbjct: 251 RSLKTDIEESKYRQ 264


>gi|110349794 homer 2 isoform 3 [Homo sapiens]
          Length = 288

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 19/74 (25%), Positives = 39/74 (52%)

Query: 188 STGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDV 247
           +T   R ++   ++  E++  LK++ K +E+   L  E + + +K+E +E+    L   V
Sbjct: 180 NTQLKRRIEELEAELREKETELKDLRKQSEIIPQLMSECEYVSEKLEAAERDNQNLEDKV 239

Query: 248 NRLKREIEKRRGAQ 261
             LK +IE+ +  Q
Sbjct: 240 RSLKTDIEESKYRQ 253


>gi|10190716 spindle pole body component 25 [Homo sapiens]
          Length = 224

 Score = 35.0 bits (79), Expect = 0.12
 Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 4/96 (4%)

Query: 179 YKTVSGSCMSTGFSRAVQTHSSKFFEEDGS--LKEVHKINEMYASLQEELKSICKKVEDS 236
           +K+   SC   G  R     S K F E  S  LKE  ++ EM+   Q ++    K +++ 
Sbjct: 20  FKSTDTSCQMAGL-RDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEK 78

Query: 237 EQAVDKLVKDVNRLKREIEKRRGAQIQAAREKNIQK 272
           +  + KL+ +V   K+E+E    A IQ  +E+  +K
Sbjct: 79  KDNLLKLIAEVKGKKQELEVLT-ANIQDLKEEYSRK 113


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 46/187 (24%), Positives = 80/187 (42%), Gaps = 30/187 (16%)

Query: 115 RLLHKNLQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYK-PQKGLFHRVPLVVANLGM 173
           RLL + LQ   SN+   F +L            +L+  + + P K +  ++   +     
Sbjct: 683 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQE--K 740

Query: 174 SEQLGYKTVSGSCMSTGFSR---------AVQTHSSKFFEEDGSLKEVHKINEMYASLQE 224
            E+L  KTV    + TG  +         A++T +S   +E   LK        +ASL E
Sbjct: 741 DEKL--KTVE-ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 225 ELKSICKKVEDSEQAVDKLV-----------KDVNRLKREI----EKRRGAQIQAAREKN 269
           ELK +  + +   ++V++L+           K V  LK+EI    E+    Q++ A++ +
Sbjct: 798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLS 857

Query: 270 IQKDPQE 276
           I    QE
Sbjct: 858 ITSKVQE 864


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 46/187 (24%), Positives = 80/187 (42%), Gaps = 30/187 (16%)

Query: 115 RLLHKNLQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYK-PQKGLFHRVPLVVANLGM 173
           RLL + LQ   SN+   F +L            +L+  + + P K +  ++   +     
Sbjct: 683 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQE--K 740

Query: 174 SEQLGYKTVSGSCMSTGFSR---------AVQTHSSKFFEEDGSLKEVHKINEMYASLQE 224
            E+L  KTV    + TG  +         A++T +S   +E   LK        +ASL E
Sbjct: 741 DEKL--KTVE-ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 225 ELKSICKKVEDSEQAVDKLV-----------KDVNRLKREI----EKRRGAQIQAAREKN 269
           ELK +  + +   ++V++L+           K V  LK+EI    E+    Q++ A++ +
Sbjct: 798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLS 857

Query: 270 IQKDPQE 276
           I    QE
Sbjct: 858 ITSKVQE 864


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 46/187 (24%), Positives = 80/187 (42%), Gaps = 30/187 (16%)

Query: 115 RLLHKNLQEHFSNQDLVFLLLTPSIITESCSTHRLEHSLYK-PQKGLFHRVPLVVANLGM 173
           RLL + LQ   SN+   F +L            +L+  + + P K +  ++   +     
Sbjct: 683 RLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQE--K 740

Query: 174 SEQLGYKTVSGSCMSTGFSR---------AVQTHSSKFFEEDGSLKEVHKINEMYASLQE 224
            E+L  KTV    + TG  +         A++T +S   +E   LK        +ASL E
Sbjct: 741 DEKL--KTVE-ELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE 797

Query: 225 ELKSICKKVEDSEQAVDKLV-----------KDVNRLKREI----EKRRGAQIQAAREKN 269
           ELK +  + +   ++V++L+           K V  LK+EI    E+    Q++ A++ +
Sbjct: 798 ELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLS 857

Query: 270 IQKDPQE 276
           I    QE
Sbjct: 858 ITSKVQE 864


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 34.3 bits (77), Expect = 0.21
 Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 8/61 (13%)

Query: 215 INEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEKRRGAQIQAAREKNIQKDP 274
           +N+    L+EE +S+C ++E +EQA + L  D+     E EKRR    +A  EKN   + 
Sbjct: 615 LNQQLLQLEEENQSVCSRMEAAEQARNALQVDL----AEAEKRR----EALWEKNTHLEA 666

Query: 275 Q 275
           Q
Sbjct: 667 Q 667


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 34.3 bits (77), Expect = 0.21
 Identities = 49/226 (21%), Positives = 88/226 (38%), Gaps = 31/226 (13%)

Query: 157 QKGLFHRVPLVVANLGMSEQLGYKTVSGSCMSTGFSRAVQTHSSKFFEEDGSLKEVHKIN 216
           +KGL H+V  +       +Q  Y+   G      F R V+       ++   L+     +
Sbjct: 323 RKGLQHQVSQI-----SKQQSNYQDEQGE--DWRFRRGVEREKQDLEKQMSDLRVQLNFS 375

Query: 217 EMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEKRRGAQIQAAREKNIQKDPQE 276
            M + L+E  +  C + +D E+A   L   V  L RE+E     Q+Q     +  K+ Q 
Sbjct: 376 AMASELEEVKR--CMERKDKEKA--HLASQVENLTRELENGEKQQLQML---DRLKEIQN 428

Query: 277 NIFLCQALRTFFPNSEFLHSCVMSLKNRHVSKSSCNYNHHLDVVDNLTLMVEHTDIPEAS 336
           +   C+A R             +S   RH   ++     +L  +     + E  +     
Sbjct: 429 HFDTCEAERKH-------ADLQISELTRHAEDATKQAERYLSELQQSEALKEEAE----- 476

Query: 337 PASTPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKAD---TGSSNQ 379
                + +K KA +   +W+ K  +L    +K+S+     TG +NQ
Sbjct: 477 --KRREDLKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQ 520


>gi|63999048 syntaxin binding protein 4 [Homo sapiens]
          Length = 553

 Score = 34.3 bits (77), Expect = 0.21
 Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%)

Query: 204 EEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEKRRGAQIQ 263
           E D +LKEV+ + E      ++ K + +++++ +Q    +V++   L+  I     AQ Q
Sbjct: 303 ERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQRQ 362

Query: 264 AAREKNIQKDPQENIFLCQA 283
           A     ++ D +E I L +A
Sbjct: 363 A---HGMEMDYEEVIRLLEA 379


>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
           [Homo sapiens]
          Length = 1388

 Score = 33.9 bits (76), Expect = 0.27
 Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 9/201 (4%)

Query: 183 SGSCMSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDK 242
           S SC  T   ++ +   S+  ++     E H  NEM A  +EEL+  CK V    +   K
Sbjct: 425 SPSCRETDSIQSRKNEESQEIQKKLYTLEEHLSNEMQA--KEELEQKCKSVNTRLEKTAK 482

Query: 243 LVKDVNRLKREIEKRRGAQIQAAREKNIQKDPQENIFLCQALRTFFPNSEFLHSCVMSLK 302
            +++   L++ +E    A  Q  REK + +   +N    +           L + V SLK
Sbjct: 483 ELEEEITLRKSVE---SALRQLEREKALLQ--HKNAEYQRKADHEADKKRNLENDVNSLK 537

Query: 303 NRHVSKSSCNYNHHL--DVVDNLTLMVEHTDIPEASPASTPQIIKHKALDLDDRWQFKRS 360
           ++       N N  +  + V+ L   ++ T+    + + T   ++    +   + Q   S
Sbjct: 538 DQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLES 597

Query: 361 RLLDTQDKRSKADTGSSNQDK 381
              D QDK    +T     +K
Sbjct: 598 NNRDLQDKNCLLETAKLKLEK 618


>gi|4758646 kinesin family member 3B [Homo sapiens]
          Length = 747

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 51/214 (23%), Positives = 85/214 (39%), Gaps = 37/214 (17%)

Query: 210 KEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEKRR----GAQIQAA 265
           +E  ++ E Y+SLQ+E+    KK++     +  +  +++ L+ E  K R      Q +  
Sbjct: 518 EETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT 577

Query: 266 REKNIQKDPQENIFLCQAL-----RTFFPNSE---FLHSCVMSLKNRHVSK---SSCNYN 314
           RE  ++    EN    +       R FF   E    LH  +  L+N+ + K   S+  Y 
Sbjct: 578 RELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHP-ITRLENQQMMKRPVSAVGYK 636

Query: 315 HHLDVVDNLTLMVE-------------HTDIPEAS------PASTP--QIIKHKALDLDD 353
             L     +++M+                D+P  +      PA  P  Q     AL  +D
Sbjct: 637 RPLSQHARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDED 696

Query: 354 RWQFKRSRLLDTQDKRSKADTGSSNQDKASKMSS 387
             Q   S    T +K+SKA   S  +  +S  SS
Sbjct: 697 EIQVDASSFESTANKKSKARPKSGRKSGSSSSSS 730


>gi|187761324 shootin1 isoform a [Homo sapiens]
          Length = 631

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 39/187 (20%), Positives = 83/187 (44%), Gaps = 20/187 (10%)

Query: 81  NEQALKKILSNVKKNVVGWY--------KFRRHSDQIMTFRERLLHKNLQEHFSNQDLVF 132
           +E+   ++++++K+  +G Y        K +   D+I   R+  + K L+E      +V 
Sbjct: 5   DEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAV-KKLEEFQKISHMVI 63

Query: 133 ----LLLTPSIITESC--STHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGYKTVSGSC 186
                +     I ++C  S   L   L K  K L     L +A LG         +    
Sbjct: 64  EEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDED 123

Query: 187 MSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKD 246
            +T    A +T  S   +     K++ ++ +   S+QEE K +  ++E+ +  + +++++
Sbjct: 124 STTDTDGAAETCVSVQCQ-----KQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEE 178

Query: 247 VNRLKRE 253
           VN++K+E
Sbjct: 179 VNKVKQE 185



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 12/47 (25%), Positives = 26/47 (55%)

Query: 210 KEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEK 256
           KE+H + +    L+E+ K +  K ++SE+    L   V+ L++ + +
Sbjct: 301 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQ 347


>gi|50511340 shootin1 isoform b [Homo sapiens]
          Length = 456

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 39/187 (20%), Positives = 83/187 (44%), Gaps = 20/187 (10%)

Query: 81  NEQALKKILSNVKKNVVGWY--------KFRRHSDQIMTFRERLLHKNLQEHFSNQDLVF 132
           +E+   ++++++K+  +G Y        K +   D+I   R+  + K L+E      +V 
Sbjct: 5   DEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAV-KKLEEFQKISHMVI 63

Query: 133 ----LLLTPSIITESC--STHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGYKTVSGSC 186
                +     I ++C  S   L   L K  K L     L +A LG         +    
Sbjct: 64  EEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDED 123

Query: 187 MSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKD 246
            +T    A +T  S   +     K++ ++ +   S+QEE K +  ++E+ +  + +++++
Sbjct: 124 STTDTDGAAETCVSVQCQ-----KQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEE 178

Query: 247 VNRLKRE 253
           VN++K+E
Sbjct: 179 VNKVKQE 185



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 12/47 (25%), Positives = 26/47 (55%)

Query: 210 KEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEK 256
           KE+H + +    L+E+ K +  K ++SE+    L   V+ L++ + +
Sbjct: 301 KEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQ 347


>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
           sapiens]
          Length = 770

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 19/74 (25%), Positives = 41/74 (55%), Gaps = 5/74 (6%)

Query: 202 FFEEDGSLKEVHKINEMYASLQE-----ELKSICKKVEDSEQAVDKLVKDVNRLKREIEK 256
           F + + +L+++HK  +    L+E     E K   KK+E S + + KL+K+  RLK++  K
Sbjct: 415 FKDAEDALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRK 474

Query: 257 RRGAQIQAAREKNI 270
              +   ++ ++++
Sbjct: 475 STSSSSVSSADESV 488


>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
          Length = 631

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 31/135 (22%), Positives = 62/135 (45%), Gaps = 20/135 (14%)

Query: 142 ESCSTHRLEHSLYKPQKGLFHRVPLVVANLGMSEQLGYKTVSGSCMSTGFSRAVQTHSSK 201
           ++  T  LE     P K   H VP V+ +           +    +  G +R +    S+
Sbjct: 86  QATDTEILERKTVLPSK---HAVPEVIEDF----------LCNFLIKMGMTRTLDCFQSE 132

Query: 202 FFE--EDG--SLKEVHKINEMYAS---LQEELKSICKKVEDSEQAVDKLVKDVNRLKREI 254
           ++E  + G   L+ V  + ++Y     L+ E K++ K ++  +QA DK  +D+ ++++E 
Sbjct: 133 WYELIQKGVTELRTVGNVPDVYTQIMLLENENKNLKKDLKHYKQAADKAREDLLKIQKER 192

Query: 255 EKRRGAQIQAAREKN 269
           +  R    +  +EKN
Sbjct: 193 DFHRMHHKRIVQEKN 207


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 15/88 (17%)

Query: 201 KFFEEDGSLKEV----------HKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRL 250
           K  E +G  KE+           K   M +SL  E+    KK+ + E+  +K + ++ +L
Sbjct: 595 KVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQL 654

Query: 251 KREIEKRRGAQIQAAREKNIQKDPQENI 278
           KRE+E      ++A   ++++ +  E +
Sbjct: 655 KRELE-----NVKAKLAQHVKPEEHEQV 677


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
           repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 15/88 (17%)

Query: 201 KFFEEDGSLKEV----------HKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRL 250
           K  E +G  KE+           K   M +SL  E+    KK+ + E+  +K + ++ +L
Sbjct: 608 KVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQL 667

Query: 251 KREIEKRRGAQIQAAREKNIQKDPQENI 278
           KRE+E      ++A   ++++ +  E +
Sbjct: 668 KRELE-----NVKAKLAQHVKPEEHEQV 690


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 28/102 (27%), Positives = 48/102 (47%), Gaps = 5/102 (4%)

Query: 180  KTVSGSCMSTGFSRAVQTHSSKFFEEDGSLKEVHKINEMYASLQ-EELKSIC--KKVEDS 236
            + V+  C      +A +       EE+  L+  + I ++ A L+ +E K +C  +++++S
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLR--NSIEKLRARLEADEKKQLCVLQQLKES 2327

Query: 237  EQAVDKLVKDVNRLKREIEKRRGAQIQAAREKNIQKDPQENI 278
            E   D L   V  L+RE+E  R  Q  AA E    K   E +
Sbjct: 2328 EHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETL 2369



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 13/47 (27%), Positives = 29/47 (61%)

Query: 209  LKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIE 255
            L+ + +    Y  LQ  +  + ++VED +Q ++K  ++++RLK +I+
Sbjct: 2486 LQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQ 2532


>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 42/206 (20%), Positives = 83/206 (40%), Gaps = 20/206 (9%)

Query: 205 EDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRL---KREIEKRRGAQ 261
           E+  L +       Y   QEEL ++ K +E+SE+ + K  K++ R    K E+ + +   
Sbjct: 724 EEADLLQTKLQQSSYHKQQEELDALKKTIEESEETL-KNTKEIQRKAEEKYEVLENKMKN 782

Query: 262 IQAAREKNIQKDPQENIFLCQALRTFFPNSEFLHSC----VMSLKNRHVSKSSCNYNHHL 317
            +A RE+ + KD Q+ +  C   +    + +          ++L+   + +   +Y   L
Sbjct: 783 AEAEREREL-KDAQKKLD-CAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQL 840

Query: 318 DVVDNLTLMVE-HTDIPEASPASTPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKADTGS 376
           + V+      E   ++  A  A   + +     ++      K+  ++  QD   KA    
Sbjct: 841 EAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVT-----KQKEVITAQDTVIKAKYAE 895

Query: 377 ----SNQDKASKMSSPETDEEIEKMK 398
                 Q+  S++   E D  I K K
Sbjct: 896 VAKHKEQNNDSQLKIKELDHNISKHK 921


>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 42/206 (20%), Positives = 83/206 (40%), Gaps = 20/206 (9%)

Query: 205 EDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRL---KREIEKRRGAQ 261
           E+  L +       Y   QEEL ++ K +E+SE+ + K  K++ R    K E+ + +   
Sbjct: 724 EEADLLQTKLQQSSYHKQQEELDALKKTIEESEETL-KNTKEIQRKAEEKYEVLENKMKN 782

Query: 262 IQAAREKNIQKDPQENIFLCQALRTFFPNSEFLHSC----VMSLKNRHVSKSSCNYNHHL 317
            +A RE+ + KD Q+ +  C   +    + +          ++L+   + +   +Y   L
Sbjct: 783 AEAEREREL-KDAQKKLD-CAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQL 840

Query: 318 DVVDNLTLMVE-HTDIPEASPASTPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKADTGS 376
           + V+      E   ++  A  A   + +     ++      K+  ++  QD   KA    
Sbjct: 841 EAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVT-----KQKEVITAQDTVIKAKYAE 895

Query: 377 ----SNQDKASKMSSPETDEEIEKMK 398
                 Q+  S++   E D  I K K
Sbjct: 896 VAKHKEQNNDSQLKIKELDHNISKHK 921


>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
          Length = 1197

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 42/206 (20%), Positives = 83/206 (40%), Gaps = 20/206 (9%)

Query: 205 EDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRL---KREIEKRRGAQ 261
           E+  L +       Y   QEEL ++ K +E+SE+ + K  K++ R    K E+ + +   
Sbjct: 724 EEADLLQTKLQQSSYHKQQEELDALKKTIEESEETL-KNTKEIQRKAEEKYEVLENKMKN 782

Query: 262 IQAAREKNIQKDPQENIFLCQALRTFFPNSEFLHSC----VMSLKNRHVSKSSCNYNHHL 317
            +A RE+ + KD Q+ +  C   +    + +          ++L+   + +   +Y   L
Sbjct: 783 AEAEREREL-KDAQKKLD-CAKTKADASSKKMKEKQQEVEAITLELEELKREHTSYKQQL 840

Query: 318 DVVDNLTLMVE-HTDIPEASPASTPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKADTGS 376
           + V+      E   ++  A  A   + +     ++      K+  ++  QD   KA    
Sbjct: 841 EAVNEAIKSYESQIEVMAAEVAKNKESVNKAQEEVT-----KQKEVITAQDTVIKAKYAE 895

Query: 377 ----SNQDKASKMSSPETDEEIEKMK 398
                 Q+  S++   E D  I K K
Sbjct: 896 VAKHKEQNNDSQLKIKELDHNISKHK 921


>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
           sapiens]
          Length = 1719

 Score = 33.1 bits (74), Expect = 0.47
 Identities = 14/54 (25%), Positives = 31/54 (57%)

Query: 208 SLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEKRRGAQ 261
           +++E  +INE    L  + + + + V D E+ VD +++ V  L++E+ +   A+
Sbjct: 575 AMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRTERAK 628



 Score = 28.9 bits (63), Expect = 8.8
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 9/69 (13%)

Query: 200 SKFFEEDGSLKEVHKINEMYASLQEELKSICKKVEDSEQAVDKLVKDVNRLKREIEKRRG 259
           S F+EE+ S +E    NE        +K++ K++ DSE     L K++  LK ++EK R 
Sbjct: 697 SIFYEEELSKREGIHANE--------IKNLKKELHDSEGQQLALNKEIMILKDKLEKTR- 747

Query: 260 AQIQAAREK 268
            + Q+ RE+
Sbjct: 748 RESQSEREE 756


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,630,637
Number of Sequences: 37866
Number of extensions: 623574
Number of successful extensions: 3763
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 3401
Number of HSP's gapped (non-prelim): 465
length of query: 409
length of database: 18,247,518
effective HSP length: 105
effective length of query: 304
effective length of database: 14,271,588
effective search space: 4338562752
effective search space used: 4338562752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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