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Search of human proteins with 109134332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
(712 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 1462 0.0
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 1462 0.0
gi|21361749 ubiquitin thioesterase 49 [Homo sapiens] 762 0.0
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 205 1e-52
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 141 2e-33
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 141 2e-33
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 141 2e-33
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 136 8e-32
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 133 5e-31
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 132 1e-30
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 119 7e-27
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 119 7e-27
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 106 9e-23
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 106 9e-23
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 105 1e-22
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 103 7e-22
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 101 2e-21
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 101 2e-21
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 101 2e-21
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 98 3e-20
gi|153792150 deubiquitinating enzyme 3 [Homo sapiens] 98 3e-20
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 96 1e-19
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 96 1e-19
gi|169172882 PREDICTED: Ubiquitin carboxyl-terminal hydrolase 17... 94 3e-19
gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 92 1e-18
gi|169172880 PREDICTED: Inactive ubiquitin carboxyl-terminal hyd... 92 2e-18
gi|169172781 PREDICTED: Inactive ubiquitin carboxyl-terminal hyd... 92 2e-18
gi|239742276 PREDICTED: hypothetical protein XP_002342471 [Homo ... 90 6e-18
gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1 ... 90 8e-18
gi|157785653 ubiquitin specific peptidase 17 [Homo sapiens] 90 8e-18
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 1462 bits (3785), Expect = 0.0
Identities = 712/712 (100%), Positives = 712/712 (100%)
Query: 1 MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKH 60
MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKH
Sbjct: 1 MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKH 60
Query: 61 FQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFL 120
FQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFL
Sbjct: 61 FQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFL 120
Query: 121 RSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPF 180
RSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPF
Sbjct: 121 RSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPF 180
Query: 181 QEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASP 240
QEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASP
Sbjct: 181 QEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASP 240
Query: 241 AKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQC 300
AKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQC
Sbjct: 241 AKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQC 300
Query: 301 FLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGA 360
FLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGA
Sbjct: 301 FLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGA 360
Query: 361 SKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYA 420
SKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYA
Sbjct: 361 SKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYA 420
Query: 421 QQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCL 480
QQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCL
Sbjct: 421 QQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCL 480
Query: 481 ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQC 540
ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQC
Sbjct: 481 ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQC 540
Query: 541 NSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNM 600
NSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNM
Sbjct: 541 NSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNM 600
Query: 601 EPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
EPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC
Sbjct: 601 EPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
Query: 661 TMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS 712
TMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS
Sbjct: 661 TMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS 712
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 1462 bits (3785), Expect = 0.0
Identities = 712/712 (100%), Positives = 712/712 (100%)
Query: 1 MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKH 60
MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKH
Sbjct: 1 MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKH 60
Query: 61 FQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFL 120
FQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFL
Sbjct: 61 FQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFL 120
Query: 121 RSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPF 180
RSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPF
Sbjct: 121 RSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPF 180
Query: 181 QEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASP 240
QEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASP
Sbjct: 181 QEKIVVKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASP 240
Query: 241 AKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQC 300
AKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQC
Sbjct: 241 AKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQC 300
Query: 301 FLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGA 360
FLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGA
Sbjct: 301 FLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGA 360
Query: 361 SKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYA 420
SKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYA
Sbjct: 361 SKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYA 420
Query: 421 QQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCL 480
QQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCL
Sbjct: 421 QQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCL 480
Query: 481 ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQC 540
ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQC
Sbjct: 481 ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYVCDQC 540
Query: 541 NSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNM 600
NSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNM
Sbjct: 541 NSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNM 600
Query: 601 EPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
EPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC
Sbjct: 601 EPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
Query: 661 TMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS 712
TMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS
Sbjct: 661 TMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEILS 712
>gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]
Length = 640
Score = 762 bits (1968), Expect = 0.0
Identities = 389/652 (59%), Positives = 470/652 (72%), Gaps = 34/652 (5%)
Query: 4 MDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKHFQE 63
MD CKHVG+L+LAQDHS LNPQKW C++C TTES+WACL CSHVACGRYIE+HALKHF+E
Sbjct: 1 MDRCKHVGRLRLAQDHSILNPQKWCCLECATTESVWACLKCSHVACGRYIEDHALKHFEE 60
Query: 64 SSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSM 123
+ HP+A+EV ++YVFCYLC DYVLNDN GDLKLLR +L A++ Q R GR LRSM
Sbjct: 61 TGHPLAMEVRDLYVFCYLCKDYVLNDNPEGDLKLLRSSLLAVRGQKQDTPVRRGRTLRSM 120
Query: 124 GTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPFQEK 183
+G+D Q Q + Q+ TALW+RR+ L+ + R WFE+S G+ K E+ QE+
Sbjct: 121 ASGEDVVL----PQRAPQGQPQMLTALWYRRQRLLARTLRLWFEKSSRGQAKLEQRRQEE 176
Query: 184 IVV--KREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPA 241
+ K E ++RR+E++ ++ EL S PPRKS RL + P + +
Sbjct: 177 ALERKKEEARRRRREVKRRLLEELASTPPRKSARLL------------LHTPRDAGPAAS 224
Query: 242 KDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCF 301
+ L TS + + ++R+P + PGVTGLRNLGNTCYMNS+LQVLSHL FR+CF
Sbjct: 225 RPAALPTSRRVPAATLK---LRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRECF 281
Query: 302 LKLDLNQW---LAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSG 358
L LD ++ + KT+ P + + D C R+ +G
Sbjct: 282 LNLDPSKTEHLFPKATNGKTQLSGKPTNSSATELSLRN----DRAEACEREGFC---WNG 334
Query: 359 GASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRG 418
AS R +ELIQ KEP+S++ISLC ELHTLF+VMWSGKWALVSPFAMLHSVW LIPAFRG
Sbjct: 335 RASISRSLELIQNKEPSSKHISLCRELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRG 394
Query: 419 YAQQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVT 478
Y QQDAQEFLCELL K+Q+ELE+ GT+ LIP SQRKL KQVL VVN IFHGQLLSQVT
Sbjct: 395 YDQQDAQEFLCELLHKVQQELESEGTTRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVT 454
Query: 479 CLACDNKSNTIEPFWDLSLEFPERYQCSGK---DIASQPCLVTEMLAKFTETEALEGKIY 535
C++C+ KSNTIEPFWDLSLEFPERY C K + CL+TEMLAKFTETEALEG+IY
Sbjct: 455 CISCNYKSNTIEPFWDLSLEFPERYHCIEKGFVPLNQTECLLTEMLAKFTETEALEGRIY 514
Query: 536 VCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE 595
CDQCNSKRR+ + KP+VL+EA+KQLMI LPQVLRLHLKRFRWSGRN+REKIGVHV F+
Sbjct: 515 ACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVFD 574
Query: 596 EILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGG 647
++L MEPYCCR+ L SL E F YDLSAVVMHHGKGFGSGHYTAYCYN+EGG
Sbjct: 575 QVLTMEPYCCRDMLSSLDKETFAYDLSAVVMHHGKGFGSGHYTAYCYNTEGG 626
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 205 bits (521), Expect = 1e-52
Identities = 154/482 (31%), Positives = 226/482 (46%), Gaps = 82/482 (17%)
Query: 218 GLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSE-NEISQKVSDSSVKRRPIVTPGVTGLR 276
GL Q + +++ A T K K+L S N KV+ S+ TGLR
Sbjct: 109 GLVQKVREHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTT------AICATGLR 162
Query: 277 NLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNE 336
NLGNTC+MN++LQ LS++ F F +L P +
Sbjct: 163 NLGNTCFMNAILQSLSNIEQFCCYFKEL--------------------PAVE-------- 194
Query: 337 CQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGK 396
L G + GR+ + +SL E +W G
Sbjct: 195 -------------------LRNGKTAGRRT--YHTRSQGDNNVSLVEEFRKTLCALWQGS 233
Query: 397 WALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELE--TTGTSLPAL----- 449
SP ++ + VW+++P FRGY QQDA EF+ LLD + EL+ G S A+
Sbjct: 234 QTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENS 293
Query: 450 -IPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCS-G 507
+ S + I VV IF G L ++V CL C +S +PF DLSL+ P +++
Sbjct: 294 TLSASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRS 353
Query: 508 KDIASQP-CLVTEMLAKFTETEAL-EGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICH 565
K+ + P C + + L FT+ E L E ++Y+C +C K++ + K+ I
Sbjct: 354 KNQENGPVCSLRDCLRSFTDLEELDETELYMCHKCKKKQK-----------STKKFWIQK 402
Query: 566 LPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVV 625
LP+VL LHLKRF W+ R K+ +V F + ++ C ++ PE +YDL+AVV
Sbjct: 403 LPKVLCLHLKRFHWTA-YLRNKVDTYVEF-PLRGLDMKCYLLEPENSGPESCLYDLAAVV 460
Query: 626 MHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHS 685
+HHG G GSGHYTAY + G W H NDS +++ + V KA+AYILFY + + G
Sbjct: 461 VHHGSGVGSGHYTAYA--THEGRWFHFNDSTVTLTDEETVVKAKAYILFYVEHQAKAGSD 518
Query: 686 KL 687
KL
Sbjct: 519 KL 520
Score = 75.9 bits (185), Expect = 1e-13
Identities = 35/119 (29%), Positives = 57/119 (47%), Gaps = 16/119 (13%)
Query: 23 NPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKHFQES----------------SH 66
+P W C C + +S W CL+CS V CGRY+ HA KH++++ H
Sbjct: 23 SPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQH 82
Query: 67 PVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSMGT 125
V ++ + +CY CDD+V+ND G ++ +R L +++ + R L T
Sbjct: 83 TVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLENST 141
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 141 bits (356), Expect = 2e-33
Identities = 137/504 (27%), Positives = 209/504 (41%), Gaps = 111/504 (22%)
Query: 200 QVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSD 259
Q+ AE + P + + I+ + P TP ++K + EIS+ +
Sbjct: 701 QIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSAS 760
Query: 260 SSVKRRPIVT---PGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316
P+ P +TGLRNLGNTCYMNS+LQ L
Sbjct: 761 QIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCL------------------------- 795
Query: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376
C P + D Y C + D +R + L G K E+ +
Sbjct: 796 ----CNAPHLAD---YFNRNCYQDDI----NRSNLL----------GHKGEVAE------ 828
Query: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436
E + + +W+G++ +SP ++ ++ F GY+QQD+QE L L+D +
Sbjct: 829 -------EFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH 881
Query: 437 REL----------ETTGTSLPALIPTSQRKLIKQVLN--VVNNIFHGQLLSQVTCLACDN 484
+L E L + LN ++ +F GQ S V CL C
Sbjct: 882 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 941
Query: 485 KSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSK 543
KS T E F LSL +C+ +D L F++ E L + + C C ++
Sbjct: 942 KSRTFEAFMYLSLPLASTSKCTLQDC----------LRLFSKEEKLTDNNRFYCSHCRAR 991
Query: 544 RRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEP 602
R ++ K++ I LP VL +HLKRF + GR ++K+ V F E L++
Sbjct: 992 R-----------DSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039
Query: 603 YCC--RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
Y + LK Y+L +V H+G G GHYTAYC N+ W +D ++S
Sbjct: 1040 YVIGPKNNLKK-------YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI 1091
Query: 661 TMDEVCKAQAYILFYTQ---RVTE 681
++ V + AYILFYT RVT+
Sbjct: 1092 SVSSVKSSAAYILFYTSLGPRVTD 1115
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 141 bits (356), Expect = 2e-33
Identities = 137/504 (27%), Positives = 209/504 (41%), Gaps = 111/504 (22%)
Query: 200 QVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSD 259
Q+ AE + P + + I+ + P TP ++K + EIS+ +
Sbjct: 701 QIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSAS 760
Query: 260 SSVKRRPIVT---PGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316
P+ P +TGLRNLGNTCYMNS+LQ L
Sbjct: 761 QIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCL------------------------- 795
Query: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376
C P + D Y C + D +R + L G K E+ +
Sbjct: 796 ----CNAPHLAD---YFNRNCYQDDI----NRSNLL----------GHKGEVAE------ 828
Query: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436
E + + +W+G++ +SP ++ ++ F GY+QQD+QE L L+D +
Sbjct: 829 -------EFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH 881
Query: 437 REL----------ETTGTSLPALIPTSQRKLIKQVLN--VVNNIFHGQLLSQVTCLACDN 484
+L E L + LN ++ +F GQ S V CL C
Sbjct: 882 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 941
Query: 485 KSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSK 543
KS T E F LSL +C+ +D L F++ E L + + C C ++
Sbjct: 942 KSRTFEAFMYLSLPLASTSKCTLQDC----------LRLFSKEEKLTDNNRFYCSHCRAR 991
Query: 544 RRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEP 602
R ++ K++ I LP VL +HLKRF + GR ++K+ V F E L++
Sbjct: 992 R-----------DSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039
Query: 603 YCC--RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
Y + LK Y+L +V H+G G GHYTAYC N+ W +D ++S
Sbjct: 1040 YVIGPKNNLKK-------YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI 1091
Query: 661 TMDEVCKAQAYILFYTQ---RVTE 681
++ V + AYILFYT RVT+
Sbjct: 1092 SVSSVKSSAAYILFYTSLGPRVTD 1115
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 141 bits (356), Expect = 2e-33
Identities = 137/504 (27%), Positives = 209/504 (41%), Gaps = 111/504 (22%)
Query: 200 QVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSD 259
Q+ AE + P + + I+ + P TP ++K + EIS+ +
Sbjct: 701 QIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSAS 760
Query: 260 SSVKRRPIVT---PGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316
P+ P +TGLRNLGNTCYMNS+LQ L
Sbjct: 761 QIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCL------------------------- 795
Query: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376
C P + D Y C + D +R + L G K E+ +
Sbjct: 796 ----CNAPHLAD---YFNRNCYQDDI----NRSNLL----------GHKGEVAE------ 828
Query: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436
E + + +W+G++ +SP ++ ++ F GY+QQD+QE L L+D +
Sbjct: 829 -------EFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH 881
Query: 437 REL----------ETTGTSLPALIPTSQRKLIKQVLN--VVNNIFHGQLLSQVTCLACDN 484
+L E L + LN ++ +F GQ S V CL C
Sbjct: 882 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 941
Query: 485 KSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSK 543
KS T E F LSL +C+ +D L F++ E L + + C C ++
Sbjct: 942 KSRTFEAFMYLSLPLASTSKCTLQDC----------LRLFSKEEKLTDNNRFYCSHCRAR 991
Query: 544 RRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEP 602
R ++ K++ I LP VL +HLKRF + GR ++K+ V F E L++
Sbjct: 992 R-----------DSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039
Query: 603 YCC--RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
Y + LK Y+L +V H+G G GHYTAYC N+ W +D ++S
Sbjct: 1040 YVIGPKNNLKK-------YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI 1091
Query: 661 TMDEVCKAQAYILFYTQ---RVTE 681
++ V + AYILFYT RVT+
Sbjct: 1092 SVSSVKSSAAYILFYTSLGPRVTD 1115
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 136 bits (342), Expect = 8e-32
Identities = 137/516 (26%), Positives = 206/516 (39%), Gaps = 115/516 (22%)
Query: 198 EYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKV 257
+Y ++E + + L ST E+ Q P K T++ E+ ++
Sbjct: 4 DYVYDKDIEQIAKEEQGEALKLQASTSTEVSHQQ--CSVPGLGEKFPTWETTKPEL--EL 59
Query: 258 SDSSVKRRPIV---TPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTA 314
+ +RR I T G+ GL NLGNTC+MN ++Q L+H I R FL
Sbjct: 60 LGHNPRRRRITSSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFL------------ 107
Query: 315 SEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEP 374
S++ R C+ P +V +M+
Sbjct: 108 SDRHR-CEMPSPELCLVCEMS--------------------------------------- 127
Query: 375 TSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDK 434
SL EL+ SG + P+ +LH VW GY QQDA EFL LD
Sbjct: 128 -----SLFRELY-------SGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDV 175
Query: 435 IQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWD 494
+ R + A P +I Q IF G L S VTC AC S TI+P WD
Sbjct: 176 LHRHCKGDDVGKAANNPNHCNCIIDQ-------IFTGGLQSDVTCQACHGVSTTIDPCWD 228
Query: 495 LSLEFP------------ERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYV-CDQCN 541
+SL+ P +G+ +T+ L +FT E L + C C
Sbjct: 229 ISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSCQ 288
Query: 542 SKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNME 601
S + E+ KQL + LP V H KRF S + R KI ++ F L+M
Sbjct: 289 SYQ-----------ESTKQLTMNKLPVVACFHFKRFEHSAK-QRRKITTYISFPLELDMT 336
Query: 602 PYCCRETLKSLRPECFI----------YDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVH 651
P+ + + + Y L AVV H G SGHYT++ + + W
Sbjct: 337 PFMASSKESRMNGQLQLPTNSGNNENKYSLFAVVNHQGT-LESGHYTSFIRHHKDQ-WFK 394
Query: 652 CNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSKL 687
C+D+ ++ ++ +V ++ Y+LFY ++V E+ K+
Sbjct: 395 CDDAVITKASIKDVLDSEGYLLFYHKQVLEHESEKV 430
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 133 bits (335), Expect = 5e-31
Identities = 129/447 (28%), Positives = 178/447 (39%), Gaps = 114/447 (25%)
Query: 263 KRRPIV---TPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTR 319
KRR I T G+ GL NLGNTC+MN ++Q L+H + R FL S++ R
Sbjct: 163 KRRKITSNCTIGLRGLINLGNTCFMNCIVQALTHTPLLRDFFL------------SDRHR 210
Query: 320 SCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYI 379
E Q + VC S SG S P P
Sbjct: 211 C---------------EMQSPSSCLVCEMSSLFQEFYSGHRS---------PHIP----- 241
Query: 380 SLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQREL 439
+ +LH VW GY QQDA EFL LD + R
Sbjct: 242 -----------------------YKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHC 278
Query: 440 ETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEF 499
+ A P +I Q IF G L S VTC C S TI+PFWD+SL+
Sbjct: 279 KGDDNGKKANNPNHCNCIIDQ-------IFTGGLQSDVTCQVCHGVSTTIDPFWDISLDL 331
Query: 500 P-------------ERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYV-CDQCNSKRR 545
P E +G+ S +T+ L +FT E L + C C+S +
Sbjct: 332 PGSSTPFWPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQ- 390
Query: 546 RFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCC 605
E+ KQL + LP V HLKRF S + R KI +V F L+M P+
Sbjct: 391 ----------ESTKQLTMKKLPIVACFHLKRFEHSAK-LRRKITTYVSFPLELDMTPFMA 439
Query: 606 -----------RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCND 654
++ SL + Y L AVV H G SGHYT++ + W C+D
Sbjct: 440 SSKESRMNGQYQQPTDSLNND-NKYSLFAVVNHQGT-LESGHYTSFIRQHKDQ-WFKCDD 496
Query: 655 SKLSMCTMDEVCKAQAYILFYTQRVTE 681
+ ++ ++ +V ++ Y+LFY ++ E
Sbjct: 497 AIITKASIKDVLDSEGYLLFYHKQFLE 523
Score = 35.4 bits (80), Expect = 0.18
Identities = 13/47 (27%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 40 ACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86
+CL C C + ++H +H + H +A+++ ++C+LC DY+
Sbjct: 75 SCLYCVFFGC--FTKKHIHEHAKAKRHNLAIDLMYGGIYCFLCQDYI 119
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 132 bits (331), Expect = 1e-30
Identities = 106/331 (32%), Positives = 152/331 (45%), Gaps = 46/331 (13%)
Query: 375 TSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDK 434
TS + L E+ +LF M+SG P+ +LH +W GY QQDA EFL +LD
Sbjct: 401 TSPSLCLVCEMSSLFHAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDV 460
Query: 435 IQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWD 494
+ R + A P +I Q IF G L S VTC AC + S TI+P WD
Sbjct: 461 LHRHSKDDSGGQEANNPNCCNCIIDQ-------IFTGGLQSDVTCQACHSVSTTIDPCWD 513
Query: 495 LSLEF-----------PERYQCS---GKDIASQPCLVTEMLAKFTETEALEGKIYV-CDQ 539
+SL+ PER + I P L T+ L FT E L + C+
Sbjct: 514 ISLDLPGSCATFDSQNPERADSTVSRDDHIPGIPSL-TDCLQWFTRPEHLGSSAKIKCNS 572
Query: 540 CNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILN 599
C S + E+ KQL + LP V HLKRF G+ R KI + F L+
Sbjct: 573 CQSYQ-----------ESTKQLTMKKLPIVACFHLKRFEHVGK-QRRKINTFISFPLELD 620
Query: 600 MEPYCC---RETLKSLRP--ECF----IYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWV 650
M P+ +K +P +C Y L AV+ HHG SGHYT++ + W
Sbjct: 621 MTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGT-LESGHYTSF-IRQQKDQWF 678
Query: 651 HCNDSKLSMCTMDEVCKAQAYILFYTQRVTE 681
C+D+ ++ T++++ ++ Y+LFY ++ E
Sbjct: 679 SCDDAIITKATIEDLLYSEGYLLFYHKQGLE 709
Score = 49.3 bits (116), Expect = 1e-05
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Query: 198 EYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKV 257
+Y ++E + ++ L ST ++ Q T K T E E
Sbjct: 290 DYVYDKDIEQIAKETKEKILRLLTSTSTDVSHQQF--MTSGFEDKQSTCETKEQEPKLVK 347
Query: 258 SDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFL 302
+++ + T G+ GL NLGNTC+MN ++Q L+H+ + + FL
Sbjct: 348 PKKKRRKKSVYTVGLRGLINLGNTCFMNCIVQALTHIPLLKDFFL 392
Score = 43.5 bits (101), Expect = 7e-04
Identities = 19/59 (32%), Positives = 33/59 (55%), Gaps = 3/59 (5%)
Query: 29 CVDCNT-TESIWACLSCSHVACGRYIEEHALKHFQESSHPVALEVNEMYVFCYLCDDYV 86
C C+T + +CLSC C + E+H KH + H +A+++ ++C++C DYV
Sbjct: 236 CHVCSTHMNRLHSCLSCVFFGC--FTEKHIHKHAETKQHHLAVDLYHGVIYCFMCKDYV 292
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 119 bits (299), Expect = 7e-27
Identities = 98/317 (30%), Positives = 145/317 (45%), Gaps = 44/317 (13%)
Query: 375 TSQYISLCHELHTLFQVMW-SGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLD 433
++ + +L E L Q +W S +VSP + R P F GY QQDAQEFL LLD
Sbjct: 99 SNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLD 158
Query: 434 KIQRELETTGTSLPALIPTSQ-------------RKLIKQVLNVVNNIFHGQLLSQVTCL 480
+ E+ T P P + RK +++ + + ++F GQL S +TC
Sbjct: 159 GLHNEVNRV-TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCT 217
Query: 481 ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEG-KIYVCDQ 539
C S +PFWDLSL +R ++ C + FT+ + L+G + C +
Sbjct: 218 DCGYCSTVFDPFWDLSLPIAKR---GYPEVTLMDC-----MRLFTKEDVLDGDEKPTCCR 269
Query: 540 CNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EIL 598
C ++R K+ I P++L LHLKRF S R K+ V F L
Sbjct: 270 CRGRKR-----------CIKKFSIQRFPKILVLHLKRFSES-RIRTSKLTTFVNFPLRDL 317
Query: 599 NMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLS 658
++ + T + +Y+L AV H G G GHYTAYC + G W NDS ++
Sbjct: 318 DLREFASENTNHA------VYNLYAVSNHSGTTMG-GHYTAYCRSPGTGEWHTFNDSSVT 370
Query: 659 MCTMDEVCKAQAYILFY 675
+ +V + AY+LFY
Sbjct: 371 PMSSSQVRTSDAYLLFY 387
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/59 (42%), Positives = 36/59 (61%), Gaps = 8/59 (13%)
Query: 235 QTPASPAKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSH 293
++P SP+ +LST + K +S + G+ GLRNLGNTC+MNS+LQ LS+
Sbjct: 28 RSPLSPSL--LLSTFVGLLLNKAKNSKSAQ------GLAGLRNLGNTCFMNSILQCLSN 78
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 119 bits (299), Expect = 7e-27
Identities = 98/317 (30%), Positives = 145/317 (45%), Gaps = 44/317 (13%)
Query: 375 TSQYISLCHELHTLFQVMW-SGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLD 433
++ + +L E L Q +W S +VSP + R P F GY QQDAQEFL LLD
Sbjct: 308 SNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLD 367
Query: 434 KIQRELETTGTSLPALIPTSQ-------------RKLIKQVLNVVNNIFHGQLLSQVTCL 480
+ E+ T P P + RK +++ + + ++F GQL S +TC
Sbjct: 368 GLHNEVNRV-TLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCT 426
Query: 481 ACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEG-KIYVCDQ 539
C S +PFWDLSL +R ++ C + FT+ + L+G + C +
Sbjct: 427 DCGYCSTVFDPFWDLSLPIAKR---GYPEVTLMDC-----MRLFTKEDVLDGDEKPTCCR 478
Query: 540 CNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EIL 598
C ++R K+ I P++L LHLKRF S R K+ V F L
Sbjct: 479 CRGRKR-----------CIKKFSIQRFPKILVLHLKRFSES-RIRTSKLTTFVNFPLRDL 526
Query: 599 NMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLS 658
++ + T + +Y+L AV H G G GHYTAYC + G W NDS ++
Sbjct: 527 DLREFASENTNHA------VYNLYAVSNHSGTTMG-GHYTAYCRSPGTGEWHTFNDSSVT 579
Query: 659 MCTMDEVCKAQAYILFY 675
+ +V + AY+LFY
Sbjct: 580 PMSSSQVRTSDAYLLFY 596
Score = 41.6 bits (96), Expect = 0.003
Identities = 17/23 (73%), Positives = 21/23 (91%)
Query: 271 GVTGLRNLGNTCYMNSVLQVLSH 293
G+ GLRNLGNTC+MNS+LQ LS+
Sbjct: 265 GLAGLRNLGNTCFMNSILQCLSN 287
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 106 bits (264), Expect = 9e-23
Identities = 87/294 (29%), Positives = 140/294 (47%), Gaps = 56/294 (19%)
Query: 411 RLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPAL-----IPTSQRK--------- 456
+ +P+F GY+QQDAQEFL L++++ E+ G P + +P+ R+
Sbjct: 289 KYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPE 348
Query: 457 -------------LIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERY 503
+++ + + ++F GQL S + C AC +S T E F DLSL P++
Sbjct: 349 LSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKG 408
Query: 504 QCSGKDIASQPCLVTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLM 562
GK ++ + C FT+ E LE + VCD+C K T + K+L
Sbjct: 409 FAGGK-VSLRDC-----FNLFTKEEELESENAPVCDRCRQK-----------TRSTKKLT 451
Query: 563 ICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEPYCCRETLKSLRPECFIYDL 621
+ P++L LHL RF + R + +K V V F + L++ + S + +Y L
Sbjct: 452 VQRFPRILVLHLNRFS-ASRGSIKKSSVGVDFPLQRLSLGDFA------SDKAGSPVYQL 504
Query: 622 SAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY 675
A+ H G GHYTA C G W NDS++S + ++V ++ Y+LFY
Sbjct: 505 YALCNHSG-SVHYGHYTALCRCQTG--WHVYNDSRVSPVSENQVASSEGYVLFY 555
Score = 43.1 bits (100), Expect = 9e-04
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 232 VPAQTPASPAKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVL 291
+ + PAS ++S +E D ++ G GLRNLGNTC++N+VLQ L
Sbjct: 172 IRTEPPASHGSFHMISARSSEPFYS-DDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCL 230
Query: 292 SHLLIFRQCFLKLDLNQ 308
S R L+ D Q
Sbjct: 231 SSTRPLRDFCLRRDFRQ 247
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 106 bits (264), Expect = 9e-23
Identities = 87/294 (29%), Positives = 140/294 (47%), Gaps = 56/294 (19%)
Query: 411 RLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPAL-----IPTSQRK--------- 456
+ +P+F GY+QQDAQEFL L++++ E+ G P + +P+ R+
Sbjct: 289 KYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRAPPILANGPVPSPPRRGGALLEEPE 348
Query: 457 -------------LIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERY 503
+++ + + ++F GQL S + C AC +S T E F DLSL P++
Sbjct: 349 LSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKG 408
Query: 504 QCSGKDIASQPCLVTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLM 562
GK ++ + C FT+ E LE + VCD+C K T + K+L
Sbjct: 409 FAGGK-VSLRDC-----FNLFTKEEELESENAPVCDRCRQK-----------TRSTKKLT 451
Query: 563 ICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEPYCCRETLKSLRPECFIYDL 621
+ P++L LHL RF + R + +K V V F + L++ + S + +Y L
Sbjct: 452 VQRFPRILVLHLNRFS-ASRGSIKKSSVGVDFPLQRLSLGDFA------SDKAGSPVYQL 504
Query: 622 SAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY 675
A+ H G GHYTA C G W NDS++S + ++V ++ Y+LFY
Sbjct: 505 YALCNHSG-SVHYGHYTALCRCQTG--WHVYNDSRVSPVSENQVASSEGYVLFY 555
Score = 43.1 bits (100), Expect = 9e-04
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 232 VPAQTPASPAKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVL 291
+ + PAS ++S +E D ++ G GLRNLGNTC++N+VLQ L
Sbjct: 172 IRTEPPASHGSFHMISARSSEPFYS-DDKMAHHTLLLGSGHVGLRNLGNTCFLNAVLQCL 230
Query: 292 SHLLIFRQCFLKLDLNQ 308
S R L+ D Q
Sbjct: 231 SSTRPLRDFCLRRDFRQ 247
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 105 bits (263), Expect = 1e-22
Identities = 117/478 (24%), Positives = 185/478 (38%), Gaps = 116/478 (24%)
Query: 229 SVQVPAQTPASPAKDKVLSTSENEISQKVSDSS---VKRRPIVTPGVTGLRNLGNTCYMN 285
S VP ++ SP KD+ L + + S +K + G GL+NLGNTC+ N
Sbjct: 65 SSSVPDKSKPSPQKDQALGDGIAPPQKVLFPSEKICLKWQQTHRVGA-GLQNLGNTCFAN 123
Query: 286 SVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNE--CQEKDTG 343
+ LQ L++ PP+ + ++ + C +
Sbjct: 124 AALQCLTYT-----------------------------PPLANYMLSHEHSKTCHAEGFC 154
Query: 344 FVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPF 403
+C+ Q+ ++ LS ++ P
Sbjct: 155 MMCTMQAHITQALSNPGD-------------------------------------VIKPM 177
Query: 404 AMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLN 463
+++ + R+ FR Q+DA EFL +D +Q+ L +++ Q
Sbjct: 178 FVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKA---------CLNGSNKLDRHTQATT 228
Query: 464 VVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAK 523
+V IF G L S+V CL C S+T +P+ D++LE A+Q V + L +
Sbjct: 229 LVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIK----------AAQS--VNKALEQ 276
Query: 524 FTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGR 582
F + E L+G+ Y C +C + A K+ I VL L LKRF
Sbjct: 277 FVKPEQLDGENSYKCSKCKK-----------MVPASKRFTIHRSSNVLTLSLKRF---AN 322
Query: 583 NNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCY 642
KI V + E L++ PY + E +Y L AV++H G +GHY +CY
Sbjct: 323 FTGGKIAKDVKYPEYLDIRPY-----MSQPNGEPIVYVLYAVLVHTGFNCHAGHY--FCY 375
Query: 643 -NSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHP 699
+ G W NDS +S + V QAY+LFY + +L P G P
Sbjct: 376 IKASNGLWYQMNDSIVSTSDIRSVLSQQAYVLFYIRSHDVKNGGELTHPTHSPGQSSP 433
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 103 bits (256), Expect = 7e-22
Identities = 82/273 (30%), Positives = 119/273 (43%), Gaps = 61/273 (22%)
Query: 453 SQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPER---------- 502
S+R+ ++ +V+++IF G +LS V CL CD S T+E F DLSL P +
Sbjct: 433 SRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLHSAI 492
Query: 503 YQ-------CSGKDIASQPCL-------------------------VTEMLAKFTETEAL 530
YQ G A+Q L + + LA F + L
Sbjct: 493 YQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLEDCLAAFFAADEL 552
Query: 531 EG-KIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIG 589
+G +Y C++C R K + LP++L +HLKRFR + KI
Sbjct: 553 KGDNMYSCERCKKLRN-----------GVKYCKVLRLPEILCIHLKRFRHEVMYSF-KIN 600
Query: 590 VHVGFE-EILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGF 648
HV F E L++ P+ +E + YDL +V+ HHG GSGHY AYC N G
Sbjct: 601 SHVSFPLEGLDLRPFLAKECTSQITT----YDLLSVICHHGTA-GSGHYIAYCQNVINGQ 655
Query: 649 WVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTE 681
W +D ++ V A+ Y+LFY + E
Sbjct: 656 WYEFDDQYVTEVHETVVQNAEGYVLFYRKSSEE 688
Score = 50.8 bits (120), Expect = 4e-06
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 5 DTCKHVGQLQLAQDHSSLNPQKWHCVDCNTT-ESIWACL--SCSHVACGRYIEEHALKHF 61
D C H+ + L K C C T ++WACL +C +V CG +H+ H
Sbjct: 6 DLCPHLDSIGEVTKEDLLLKSKGTCQSCGVTGPNLWACLQVACPYVGCGESFADHSTIHA 65
Query: 62 QESSHPVALEVNEMYVFCYLCDDYV 86
Q H + + + ++CY C+ V
Sbjct: 66 QAKKHNLTVNLTTFRLWCYACEKEV 90
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/76 (36%), Positives = 41/76 (53%), Gaps = 1/76 (1%)
Query: 375 TSQYISLCHELHTLFQVMWSGKW-ALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLD 433
T + +LC L +W K + V P ++ H + + P FRGYAQQD QEFL L+D
Sbjct: 182 TDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMD 241
Query: 434 KIQRELETTGTSLPAL 449
++ EL+ + AL
Sbjct: 242 QLHEELKEPVVATVAL 257
Score = 44.3 bits (103), Expect = 4e-04
Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 6/67 (8%)
Query: 237 PASPAKDKVLSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLI 296
P+ P K ++ ++ S+ D R G+TG++NLGN+CYMN+ LQ LS+
Sbjct: 115 PSHPLKAVPIAVADEGESESEDDDLKPR------GLTGMKNLGNSCYMNAALQALSNCPP 168
Query: 297 FRQCFLK 303
Q FL+
Sbjct: 169 LTQFFLE 175
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 101 bits (252), Expect = 2e-21
Identities = 82/279 (29%), Positives = 123/279 (44%), Gaps = 46/279 (16%)
Query: 400 VSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIK 459
+ P + + + ++ FR Q+DA EFL +D +Q+ L ++
Sbjct: 185 IKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKA---------CLNGCAKLDRQT 235
Query: 460 QVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTE 519
Q +V+ IF G L S+V C C + S+T +P+ D++LE Q +
Sbjct: 236 QATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEI------------RQAANIVR 283
Query: 520 MLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRF- 577
L F + + L G+ Y+C +C K A K+ I VL L LKRF
Sbjct: 284 ALELFVKADVLSGENAYMCAKCKKK-----------VPASKRFTIHRTSNVLTLSLKRFA 332
Query: 578 RWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHY 637
+SG KI VG+ E LN+ PY + + +Y L AV++H G +GHY
Sbjct: 333 NFSG----GKITKDVGYPEFLNIRPY-----MSQNNGDPVMYGLYAVLVHSGYSCHAGHY 383
Query: 638 TAYCY-NSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY 675
YCY + G W NDS + + V QAY+LFY
Sbjct: 384 --YCYVKASNGQWYQMNDSLVHSSNVKVVLNQQAYVLFY 420
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 101 bits (252), Expect = 2e-21
Identities = 109/465 (23%), Positives = 175/465 (37%), Gaps = 131/465 (28%)
Query: 257 VSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316
+ D + +RR GL NLG TCY+N+ LQV FL L+L Q L + S
Sbjct: 75 IDDPNCERRK--KNSFVGLTNLGATCYVNTFLQVW---------FLNLELRQALYLCPS- 122
Query: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376
+C + D + +EKD EP +
Sbjct: 123 ---TCSDYMLGDGIQ------EEKDY------------------------------EPQT 143
Query: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436
+C L LF ++ + + P + ++ QQDAQEF
Sbjct: 144 ----ICEHLQYLFALLQNSNRRYIDPSGFVKAL-----GLDTGQQQDAQEF--------- 185
Query: 437 RELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLS 496
+ + L T ++ V N+V F G+ C C +S + F++L
Sbjct: 186 -----SKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELE 240
Query: 497 LEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEG-KIYVCDQCNSKRRRFSSKPVVLT 555
L Q +T+ +++F + E LEG Y C+ C SK+
Sbjct: 241 LNIQGHKQ------------LTDCISEFLKEEKLEGDNRYFCENCQSKQN---------- 278
Query: 556 EAQKQLMICHLPQVLRLHLKRFRWSGRN-NREKIGVHVGFEEILNMEPYCCRETLKSLRP 614
A +++ + LP L L L RF + + +++K+ ++GF EIL+MEPY +
Sbjct: 279 -ATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYV------EHKG 331
Query: 615 ECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLS---------------- 658
++Y+LSAV++H G SGHY A+ + + G W ND +
Sbjct: 332 GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLA 391
Query: 659 ----------MCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELL 693
C C AY+L Y + E ++ + P L
Sbjct: 392 EPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFL 436
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 101 bits (252), Expect = 2e-21
Identities = 109/465 (23%), Positives = 175/465 (37%), Gaps = 131/465 (28%)
Query: 257 VSDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316
+ D + +RR GL NLG TCY+N+ LQV FL L+L Q L + S
Sbjct: 75 IDDPNCERRK--KNSFVGLTNLGATCYVNTFLQVW---------FLNLELRQALYLCPS- 122
Query: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376
+C + D + +EKD EP +
Sbjct: 123 ---TCSDYMLGDGIQ------EEKDY------------------------------EPQT 143
Query: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436
+C L LF ++ + + P + ++ QQDAQEF
Sbjct: 144 ----ICEHLQYLFALLQNSNRRYIDPSGFVKAL-----GLDTGQQQDAQEF--------- 185
Query: 437 RELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLS 496
+ + L T ++ V N+V F G+ C C +S + F++L
Sbjct: 186 -----SKLFMSLLEDTLSKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFYELE 240
Query: 497 LEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEG-KIYVCDQCNSKRRRFSSKPVVLT 555
L Q +T+ +++F + E LEG Y C+ C SK+
Sbjct: 241 LNIQGHKQ------------LTDCISEFLKEEKLEGDNRYFCENCQSKQN---------- 278
Query: 556 EAQKQLMICHLPQVLRLHLKRFRWSGRN-NREKIGVHVGFEEILNMEPYCCRETLKSLRP 614
A +++ + LP L L L RF + + +++K+ ++GF EIL+MEPY +
Sbjct: 279 -ATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEILDMEPYV------EHKG 331
Query: 615 ECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLS---------------- 658
++Y+LSAV++H G SGHY A+ + + G W ND +
Sbjct: 332 GSYVYELSAVLIHRGVSAYSGHYIAHVKDPQSGEWYKFNDEDIEKMEGKKLQLGIEEDLA 391
Query: 659 ----------MCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELL 693
C C AY+L Y + E ++ + P L
Sbjct: 392 EPSKSQTRKPKCGKGTHCSRNAYMLVYRLQTQEKPNTTVQVPAFL 436
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 97.8 bits (242), Expect = 3e-20
Identities = 112/421 (26%), Positives = 171/421 (40%), Gaps = 109/421 (25%)
Query: 274 GLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQ 333
GL N GNTCY NSVLQ L FR EK + K P
Sbjct: 40 GLVNFGNTCYCNSVLQALYFCRPFR-----------------EKVLAYKSQP-------- 74
Query: 334 MNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMW 393
++K++ C L+ A++ +K+ +I PK+ +I+ + + LF
Sbjct: 75 ----RKKESLLTC-----LADLFHSIATQKKKVGVIPPKK----FITRLRKENELFD--- 118
Query: 394 SGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKI------QRELETTGTSLP 447
Y QQDA EFL LL+ I +R+ E LP
Sbjct: 119 ------------------------NYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRLP 154
Query: 448 ALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSG 507
++ V+ IF G L ++ CL C+ S+ E F DLS++
Sbjct: 155 NGNIDNENNNSTPDPTWVDEIFQGTLTNETRCLTCETISSKDEDFLDLSVD--------- 205
Query: 508 KDIASQPCLVTEMLAKFTETEALEGKI-YVCDQCNSKRRRFSSKPVVLTEAQKQLMICHL 566
Q +T L F+ TE L + Y C++C SK+ EA K++ + L
Sbjct: 206 ---VEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQ-----------EAHKRMKVKKL 251
Query: 567 PQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVM 626
P +L LHLKRF++ + +R + + + +E + + P+ +YDL AVV+
Sbjct: 252 PMILALHLKRFKYMDQLHRY---TKLSYRVVFPLELRLFNTSGDATNPD-RMYDLVAVVV 307
Query: 627 HHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY--TQRVTENGH 684
H G G GHY A + + FW+ +D + E AQA FY T +++N
Sbjct: 308 HCGSGPNRGHYIAIVKSHD--FWLLFDDD------IVEKIDAQAIEEFYGLTSDISKNSE 359
Query: 685 S 685
S
Sbjct: 360 S 360
>gi|153792150 deubiquitinating enzyme 3 [Homo sapiens]
Length = 530
Score = 97.8 bits (242), Expect = 3e-20
Identities = 85/292 (29%), Positives = 132/292 (45%), Gaps = 44/292 (15%)
Query: 397 WALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPT-SQR 455
WAL SP ++ L F Q+DA EFL +D +++ A +P Q
Sbjct: 134 WALHSPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKK----------ACLPGHKQV 183
Query: 456 KLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPC 515
+ +++ IF G SQ+ CL C S+T +P+ D++L+ A+Q
Sbjct: 184 DHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQ----------AAQS- 232
Query: 516 LVTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHL 574
V + L + + E L G+ Y C C + A K L + +VL L L
Sbjct: 233 -VKQALEQLVKPEELNGENAYHCGLCLQR-----------APASKTLTLHTSAKVLILVL 280
Query: 575 KRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGS 634
KRF N K+ +V + E L+M+PY ++ L +Y L AV++H G
Sbjct: 281 KRFSDVTGN---KLAKNVQYPECLDMQPYMSQQNTGPL-----VYVLYAVLVHAGWSCHD 332
Query: 635 GHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSK 686
GHY +Y EG W +D+K++ C++ V QAY+LFY Q+ HS+
Sbjct: 333 GHYFSYVKAQEGQ-WYKMDDAKVTACSITSVLSQQAYVLFYIQKSEWERHSE 383
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 95.9 bits (237), Expect = 1e-19
Identities = 117/422 (27%), Positives = 168/422 (39%), Gaps = 111/422 (26%)
Query: 274 GLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQ 333
GL N GNTCY NSVLQ L FR+ LA A +K
Sbjct: 29 GLVNFGNTCYCNSVLQALYFCRPFRE--------NVLAYKAQQK---------------- 64
Query: 334 MNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMW 393
+K+ C L+ A++ +K+ +I PK+ +IS + + LF
Sbjct: 65 -----KKENLLTC-----LADLFHSIATQKKKVGVIPPKK----FISRLRKENDLFD--- 107
Query: 394 SGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKI------QRELETTGTSLP 447
Y QQDA EFL LL+ I +++ E L
Sbjct: 108 ------------------------NYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLK 143
Query: 448 ALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSG 507
+ K L V+ IF G L ++ CL C+ S+ E F DLS++
Sbjct: 144 NGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVD--------- 194
Query: 508 KDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHL 566
Q +T L F+ TE L + Y C+ C SK+ EAQK++ + L
Sbjct: 195 ---VEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQ-----------EAQKRMRVKKL 240
Query: 567 PQVLRLHLKRFRWSGRNNR-EKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVV 625
P +L LHLKRF++ + +R K+ V F L + + +L +YDL AVV
Sbjct: 241 PMILALHLKRFKYMEQLHRYTKLSYRVVFP--LELRLFNTSSDAVNLDR---MYDLVAVV 295
Query: 626 MHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY--TQRVTENG 683
+H G G GHY GFW+ +D + E AQA FY T +++N
Sbjct: 296 VHCGSGPNRGHYITIV--KSHGFWLLFDDD------IVEKIDAQAIEEFYGLTSDISKNS 347
Query: 684 HS 685
S
Sbjct: 348 ES 349
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 95.9 bits (237), Expect = 1e-19
Identities = 117/422 (27%), Positives = 168/422 (39%), Gaps = 111/422 (26%)
Query: 274 GLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQ 333
GL N GNTCY NSVLQ L FR+ LA A +K
Sbjct: 36 GLVNFGNTCYCNSVLQALYFCRPFRE--------NVLAYKAQQK---------------- 71
Query: 334 MNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMW 393
+K+ C L+ A++ +K+ +I PK+ +IS + + LF
Sbjct: 72 -----KKENLLTC-----LADLFHSIATQKKKVGVIPPKK----FISRLRKENDLFD--- 114
Query: 394 SGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKI------QRELETTGTSLP 447
Y QQDA EFL LL+ I +++ E L
Sbjct: 115 ------------------------NYMQQDAHEFLNYLLNTIADILQEEKKQEKQNGKLK 150
Query: 448 ALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSG 507
+ K L V+ IF G L ++ CL C+ S+ E F DLS++
Sbjct: 151 NGNMNEPAENNKPELTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVD--------- 201
Query: 508 KDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHL 566
Q +T L F+ TE L + Y C+ C SK+ EAQK++ + L
Sbjct: 202 ---VEQNTSITHCLRDFSNTETLCSEQKYYCETCCSKQ-----------EAQKRMRVKKL 247
Query: 567 PQVLRLHLKRFRWSGRNNR-EKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVV 625
P +L LHLKRF++ + +R K+ V F L + + +L +YDL AVV
Sbjct: 248 PMILALHLKRFKYMEQLHRYTKLSYRVVFP--LELRLFNTSSDAVNLDR---MYDLVAVV 302
Query: 626 MHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFY--TQRVTENG 683
+H G G GHY GFW+ +D + E AQA FY T +++N
Sbjct: 303 VHCGSGPNRGHYITIV--KSHGFWLLFDDD------IVEKIDAQAIEEFYGLTSDISKNS 354
Query: 684 HS 685
S
Sbjct: 355 ES 356
>gi|169172882 PREDICTED: Ubiquitin carboxyl-terminal hydrolase
17-like protein 3 [Homo sapiens]
Length = 530
Score = 94.4 bits (233), Expect = 3e-19
Identities = 82/292 (28%), Positives = 131/292 (44%), Gaps = 44/292 (15%)
Query: 397 WALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPT-SQR 455
WAL SP ++ L F Q+D EFL +D +++ A +P Q
Sbjct: 134 WALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKK----------ACLPGHKQV 183
Query: 456 KLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPC 515
+ +++ IF G SQ+ CL C S+T +P+ D++L+ A+Q
Sbjct: 184 DHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQ----------AAQS- 232
Query: 516 LVTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHL 574
V + L + + E L G+ Y C C + A L + +VL L L
Sbjct: 233 -VKQALEQLVKPEELNGENAYHCGLCLQR-----------APASNTLTLHTSAKVLILVL 280
Query: 575 KRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGS 634
KRF N K+ +V + E L+M+PY ++ L +Y L AV++H G
Sbjct: 281 KRFSDVAGN---KLAKNVQYPECLDMQPYMSQQNTGPL-----VYVLYAVLVHAGWSCHD 332
Query: 635 GHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSK 686
GHY +Y EG W +D+++++C++ V QAY+LFY Q+ HS+
Sbjct: 333 GHYFSYVKAQEGQ-WYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSE 383
>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
Length = 339
Score = 92.4 bits (228), Expect = 1e-18
Identities = 81/274 (29%), Positives = 116/274 (42%), Gaps = 39/274 (14%)
Query: 382 CHELHTLFQV----MWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQR 437
C E+ T F MW G VSP ++ L PAF QQDAQEFL +L+++
Sbjct: 90 CSEVATAFAYLMTDMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHE 149
Query: 438 ELETTGTSLPALIPTSQ-----RKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPF 492
L+ S RK I +++ +F QL + CL C+ + E F
Sbjct: 150 ALKKYHYSRRRSYEKGSTQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVF 209
Query: 493 WDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEALEGKIYV-CDQCNSKRRRFSSKP 551
SL P +Y+CS +D L F + +AL + C C +K+
Sbjct: 210 TVFSLPIPSKYECSLRD----------CLQCFFQQDALTWNNEIHCSFCETKQ------- 252
Query: 552 VVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNRE-KIGVHVGFEEILNMEPYCCRETLK 610
E + I P+++ HLKRF G R+ + +H L++ PY C K
Sbjct: 253 ----ETAVRASISKAPKIIIFHLKRFDIQGTTKRKLRTDIHYPLTN-LDLTPYICSIFRK 307
Query: 611 SLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNS 644
+ Y+L AVV H G GHYTA+C NS
Sbjct: 308 YPK-----YNLCAVVNHFG-DLDGGHYTAFCKNS 335
>gi|169172880 PREDICTED: Inactive ubiquitin carboxyl-terminal
hydrolase 17-like protein 8 [Homo sapiens]
Length = 530
Score = 92.0 bits (227), Expect = 2e-18
Identities = 82/292 (28%), Positives = 132/292 (45%), Gaps = 44/292 (15%)
Query: 397 WALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPT-SQR 455
WAL SP ++ L F Q+DA EFL +D +++ A +P Q
Sbjct: 134 WALHSPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKK----------ACLPGHKQV 183
Query: 456 KLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPC 515
+ +++ IF G SQ+ CL C S+T +P+ D++L+ A+Q
Sbjct: 184 DHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQ----------AAQS- 232
Query: 516 LVTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHL 574
V + L + + E L G+ Y C C + A L + +VL L L
Sbjct: 233 -VKQALEQLVKPEELNGENAYPCGLCLQR-----------APASNTLTLHTSAKVLILVL 280
Query: 575 KRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGS 634
KRF N K+ +V + E L+M+PY ++ L +Y L AV++H G +
Sbjct: 281 KRFCDVTGN---KLAKNVQYPECLDMQPYMSQQNTGPL-----VYVLYAVLVHAGWSCHN 332
Query: 635 GHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSK 686
G+Y +Y EG W +D++++ C++ V QAY+LFY Q+ HS+
Sbjct: 333 GYYFSYVKAQEGQ-WYKMDDAEVTACSITSVLSQQAYVLFYIQKSEWERHSE 383
>gi|169172781 PREDICTED: Inactive ubiquitin carboxyl-terminal
hydrolase 17-like protein 4 [Homo sapiens]
Length = 530
Score = 92.0 bits (227), Expect = 2e-18
Identities = 81/292 (27%), Positives = 131/292 (44%), Gaps = 44/292 (15%)
Query: 397 WALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPT-SQR 455
WAL SP ++ L F Q+D EFL +D +++ A +P Q
Sbjct: 134 WALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKK----------ACLPGHKQV 183
Query: 456 KLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPC 515
+ +++ IF G SQ+ CL C S+T +P+ D++L+ A+Q
Sbjct: 184 DHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQ----------AAQS- 232
Query: 516 LVTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHL 574
V + L + + E L G+ Y C C + A L + +VL L L
Sbjct: 233 -VKQALEQLVKPEELNGENAYHCGLCLQR-----------APASNTLTLHTSAKVLILVL 280
Query: 575 KRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGS 634
KRF N K+ +V + E L+M+PY ++ L +Y L AV++H G
Sbjct: 281 KRFSDVAGN---KLAKNVQYPECLDMQPYMSQQNTGPL-----VYVLYAVLVHAGWSCHD 332
Query: 635 GHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSK 686
G+Y +Y EG W +D+++++C++ V QAY+LFY Q+ HS+
Sbjct: 333 GYYFSYVKAQEGQ-WYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSE 383
>gi|239742276 PREDICTED: hypothetical protein XP_002342471 [Homo
sapiens]
Length = 530
Score = 90.1 bits (222), Expect = 6e-18
Identities = 82/291 (28%), Positives = 132/291 (45%), Gaps = 44/291 (15%)
Query: 398 ALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPT-SQRK 456
AL P ++ L F Q+DA EFL +D +++ A +P Q
Sbjct: 135 ALHIPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMRK----------ACLPGHKQVD 184
Query: 457 LIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCL 516
+ +++ IF G SQ+ CL C S+T +P+ D++L+ A+Q
Sbjct: 185 RHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQ----------AAQS-- 232
Query: 517 VTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLK 575
V + L + + E L G+ Y C C + A K L + + +VL L LK
Sbjct: 233 VQQALEQLVKPEELNGENAYHCGVCLQR-----------APASKTLTLHNSAKVLILVLK 281
Query: 576 RFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSG 635
RF N KI +V + E L+M+PY ++ L +Y L AV++H G +G
Sbjct: 282 RFPDVTGN---KIAKNVQYPECLDMQPYMSQQNTGPL-----VYVLYAVLVHAGWSCHNG 333
Query: 636 HYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSK 686
HY++Y EG W +D++++ ++ V QAY+LFY Q+ HS+
Sbjct: 334 HYSSYVKAQEGQ-WYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSE 383
Score = 33.9 bits (76), Expect = 0.54
Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 8/73 (10%)
Query: 226 EIVSVQVPAQTPASPAKDKV-----LSTSENEISQKVSDSSVKRRPIVTPGVTGLRNLGN 280
EI +P ++P S + +V L+ +++ + RRP GL+N+GN
Sbjct: 31 EIQRTSLPEKSPLS-CETRVDLCDDLAPVARQLAPREKPPLSSRRPAAVGA--GLQNMGN 87
Query: 281 TCYMNSVLQVLSH 293
TCY+N+ LQ L++
Sbjct: 88 TCYVNASLQCLTY 100
>gi|169217654 PREDICTED: similar to deubiquitinating enzyme DUB1
[Homo sapiens]
Length = 530
Score = 89.7 bits (221), Expect = 8e-18
Identities = 82/291 (28%), Positives = 131/291 (45%), Gaps = 44/291 (15%)
Query: 398 ALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPT-SQRK 456
AL +P ++ L F Q+DA EFL +D +++ A +P Q
Sbjct: 135 ALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKK----------ACLPGHKQAD 184
Query: 457 LIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKDIASQPCL 516
+ +++ IF G SQ+ CL C S+T +P+ D++L+ A+Q
Sbjct: 185 HHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQ----------AAQS-- 232
Query: 517 VTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLK 575
V + L + + E L G+ Y C C + A K L + +VL L LK
Sbjct: 233 VQQALEQLVKPEELNGENAYHCGVCLQR-----------APASKTLTLHTSAKVLILVLK 281
Query: 576 RFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSG 635
RF N KI +V + E L+M+PY ++ L +Y L AV++H G +G
Sbjct: 282 RFSDVTGN---KIAKNVQYPECLDMQPYMSQQNTGPL-----VYVLYAVLVHAGWSCHNG 333
Query: 636 HYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSK 686
HY +Y EG W +D++++ ++ V QAY+LFY Q+ HS+
Sbjct: 334 HYFSYVKAQEGQ-WYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSE 383
Score = 33.1 bits (74), Expect = 0.92
Identities = 15/30 (50%), Positives = 21/30 (70%), Gaps = 2/30 (6%)
Query: 264 RRPIVTPGVTGLRNLGNTCYMNSVLQVLSH 293
RRP GL+N+GNTCY+N+ LQ L++
Sbjct: 73 RRPAAVGA--GLQNMGNTCYVNASLQCLTY 100
>gi|157785653 ubiquitin specific peptidase 17 [Homo sapiens]
Length = 530
Score = 89.7 bits (221), Expect = 8e-18
Identities = 104/427 (24%), Positives = 168/427 (39%), Gaps = 120/427 (28%)
Query: 264 RRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKH 323
RRP GL+N+GNTCY+N+ L+ WL T
Sbjct: 73 RRPAAVGA--GLQNMGNTCYVNASLE-------------------WLTYT---------- 101
Query: 324 PPVTDTVVYQMNE--CQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISL 381
PP+ + ++ + + C +C+ Q+ ++ L +IQP +
Sbjct: 102 PPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPG------HVIQPSQA------- 148
Query: 382 CHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRELET 441
L F Q+DA EFL +D +++
Sbjct: 149 ------------------------------LAAGFHRGKQEDAHEFLMFTVDAMKK---- 174
Query: 442 TGTSLPALIPT-SQRKLIKQVLNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFP 500
A +P Q + +++ IF G SQ+ CL C S+T +P+ D++L+
Sbjct: 175 ------ACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQ 228
Query: 501 ERYQCSGKDIASQPCLVTEMLAKFTETEALEGK-IYVCDQCNSKRRRFSSKPVVLTEAQK 559
A+Q V + L + + E L G+ Y C C + A K
Sbjct: 229 ----------AAQS--VQQALEQLVKPEELNGENAYHCGVCLQR-----------APASK 265
Query: 560 QLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIY 619
L + +VL L LKRF N KI +V + E L+M+PY ++ L +Y
Sbjct: 266 TLTLHTSAKVLILVLKRFSDVTGN---KIAKNVQYPECLDMQPYMSQQNTGPL-----VY 317
Query: 620 DLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMCTMDEVCKAQAYILFYTQRV 679
L AV++H G +GHY +Y EG W +D++++ ++ V QAY+LFY Q+
Sbjct: 318 VLYAVLVHAGWSCHNGHYFSYVKAQEGQ-WYKMDDAEVTASSITSVLSQQAYVLFYIQKS 376
Query: 680 TENGHSK 686
HS+
Sbjct: 377 EWERHSE 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,907,152
Number of Sequences: 37866
Number of extensions: 1258950
Number of successful extensions: 4568
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 4048
Number of HSP's gapped (non-prelim): 312
length of query: 712
length of database: 18,247,518
effective HSP length: 109
effective length of query: 603
effective length of database: 14,120,124
effective search space: 8514434772
effective search space used: 8514434772
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.