Search of human proteins with 4557779

Search of human proteins with 4557779

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557779 myocilin [Homo sapiens]
         (504 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557779 myocilin [Homo sapiens]                                   1013   0.0  
gi|17136143 olfactomedin related ER localized protein isoform 1 ...   223   3e-58
gi|17157993 olfactomedin 2 [Homo sapiens]                             221   2e-57
gi|166706897 olfactomedin 3 [Homo sapiens]                            201   1e-51
gi|163792198 latrophilin 3 precursor [Homo sapiens]                   186   6e-47
gi|6912464 latrophilin 2 precursor [Homo sapiens]                     177   2e-44
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]          172   5e-43
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]          172   5e-43
gi|116014339 olfactomedin-like 2A [Homo sapiens]                      172   6e-43
gi|46195719 olfactomedin-like 2B [Homo sapiens]                       166   6e-41
gi|32313593 olfactomedin 4 precursor [Homo sapiens]                   142   5e-34
gi|9910270 olfactomedin-like 3 [Homo sapiens]                         125   1e-28
gi|38348264 olfactomedin-like 1 [Homo sapiens]                        117   2e-26
gi|98986321 gliomedin [Homo sapiens]                                   91   3e-18
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    52   2e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    52   2e-06
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|112420968 coiled-coil domain containing 158 [Homo sapiens]          45   2e-04
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    44   3e-04
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C...    44   3e-04
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     44   3e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                44   3e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    44   3e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    44   3e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    44   3e-04
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi...    44   3e-04
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    44   4e-04
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  44   4e-04
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    43   6e-04
gi|21735548 centrosomal protein 2 [Homo sapiens]                       42   0.001

>gi|4557779 myocilin [Homo sapiens]
          Length = 504

 Score = 1013 bits (2618), Expect = 0.0
 Identities = 504/504 (100%), Positives = 504/504 (100%)

Query: 1   MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESS 60
           MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESS
Sbjct: 1   MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESS 60

Query: 61  CPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRE 120
           CPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRE
Sbjct: 61  CPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRE 120

Query: 121 LGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
           LGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL
Sbjct: 121 LGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180

Query: 181 RRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGE 240
           RRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGE
Sbjct: 181 RRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGE 240

Query: 241 GDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFE 300
           GDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFE
Sbjct: 241 GDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFE 300

Query: 301 YDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEI 360
           YDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEI
Sbjct: 301 YDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEI 360

Query: 361 PGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETN 420
           PGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETN
Sbjct: 361 PGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETN 420

Query: 421 IRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYN 480
           IRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYN
Sbjct: 421 IRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYN 480

Query: 481 PLEKKLFAWDNLNMVTYDIKLSKM 504
           PLEKKLFAWDNLNMVTYDIKLSKM
Sbjct: 481 PLEKKLFAWDNLNMVTYDIKLSKM 504


>gi|17136143 olfactomedin related ER localized protein isoform 1
           [Homo sapiens]
          Length = 467

 Score =  223 bits (568), Expect = 3e-58
 Identities = 133/407 (32%), Positives = 211/407 (51%), Gaps = 25/407 (6%)

Query: 110 PQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARR 169
           PQ+T          LR+  ++++  ++ +E       RD   +E+ + +++       + 
Sbjct: 62  PQQTMCSRDARTKQLRQLLEKVQNMSQSIEVLDRRTQRDLQYVEKMENQMKGLESKFKQV 121

Query: 170 LESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILK 229
            ES  Q +AR  +       D  R + P   E        L F+E    LT V     L+
Sbjct: 122 EESHKQHLARQFKA-IKAKMDELRPLIPVLEEYKADAKLVLQFKEEVQNLTSVLNE--LQ 178

Query: 230 ESPSGY---------------LRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDP 274
           E    Y               LR+      CG+L  + +P+T++T+ +   ++G WM DP
Sbjct: 179 EEIGAYDYDELQSRVSNLEERLRACMQKLACGKLTGISDPVTVKTSGS---RFGSWMTDP 235

Query: 275 KPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSL 334
               P      W +D    + R V EY  +  FM       H LP P   TG VVY+GS+
Sbjct: 236 LA--PEGDNRVWYMDGYHNN-RFVREYKSMVDFMNTDNFTSHRLPHPWSGTGQVVYNGSI 292

Query: 335 YFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYST 394
           YF   +S  +IR++L TET+   + +  AGY+  + Y+WGG++DIDL VDE+GLW +Y+T
Sbjct: 293 YFNKFQSHIIIRFDLKTETILKTRSLDYAGYNNMYHYAWGGHSDIDLMVDESGLWAVYAT 352

Query: 395 DEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYD 454
           ++  G IV+S+L+P +L+  QTW T+  K+S   AFIICGTLY  + Y S    V++AY 
Sbjct: 353 NQNAGNIVVSRLDPVSLQTLQTWNTSYPKRSAGEAFIICGTLYVTNGY-SGGTKVHYAYQ 411

Query: 455 TGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKL 501
           T     + + IPF+N+Y + SM+DYNP ++ L+AW+N + + Y++ L
Sbjct: 412 TNASTYEYIDIPFQNKYSHISMLDYNPKDRALYAWNNGHQILYNVTL 458


>gi|17157993 olfactomedin 2 [Homo sapiens]
          Length = 454

 Score =  221 bits (562), Expect = 2e-57
 Identities = 154/491 (31%), Positives = 237/491 (48%), Gaps = 65/491 (13%)

Query: 20  LLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSS 79
           LLLL C          Q    N + G   YT + A   +  C     A S      R   
Sbjct: 10  LLLLLC-----SGLAGQTLFQNPEEGWQLYTSAQAPDGKCICTAVIPAQSTCSRDGRSRE 64

Query: 80  TQRLDLEATKARLSSLESLLHQLTLD-QAARPQETQEGLQRELGTLRRERD-QLETQT-R 136
            ++L +E  +    S+E L  +   D Q  R  ET   L R L    R  D  L  ++ +
Sbjct: 65  LRQL-MEKVQNVSQSMEVLELRTYRDLQYVRGMET---LMRSLDARLRAADGSLSAKSFQ 120

Query: 137 ELETAYSNLLRDKSVLEEEKK------RLRQENENLARRLESSSQEVARLRRGQCPQTRD 190
           EL+   + LL   SVLE+ K       RLR+E  NL+  L +  +E+             
Sbjct: 121 ELKDRMTELLPLSSVLEQYKADTRTIVRLREEVRNLSGSLAAIQEEMG------------ 168

Query: 191 TARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVW 250
                                +++L+  +  + A           L +     GCG+L  
Sbjct: 169 ------------------AYGYEDLQQRVMALEAR----------LHACAQKLGCGKLTG 200

Query: 251 VGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQG 310
           V  P+T+R    +  ++G WM D     P      W +D      R+V E+  +  F++G
Sbjct: 201 VSNPITVRA---MGSRFGSWMTDTMA--PSADSRVWYMDGYYKG-RRVLEFRTLGDFIKG 254

Query: 311 YPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFP 370
                H+LP+P   TG VVY+GSL++   +S  V++Y   + +V  ++ +PGAGY+  FP
Sbjct: 255 QNFIQHLLPQPWAGTGHVVYNGSLFYNKYQSNVVVKYHFRSRSVLVQRSLPGAGYNNTFP 314

Query: 371 YSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAF 430
           YSWGG++D+D  VDE+GLW +Y+T++  G IV+S+L+P  LE+ ++W+T   K+S   AF
Sbjct: 315 YSWGGFSDMDFMVDESGLWAVYTTNQNAGNIVVSRLDPHTLEVMRSWDTGYPKRSAGEAF 374

Query: 431 IICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWD 490
           +ICG LY  +S+  A A V FAY T T   +   +PF N+Y + SM+DYNP E+ L+ W+
Sbjct: 375 MICGVLYVTNSHL-AGAKVYFAYFTNTSSYEYTDVPFHNQYSHISMLDYNPRERALYTWN 433

Query: 491 NLNMVTYDIKL 501
           N + V Y++ L
Sbjct: 434 NGHQVLYNVTL 444


>gi|166706897 olfactomedin 3 [Homo sapiens]
          Length = 458

 Score =  201 bits (512), Expect = 1e-51
 Identities = 144/467 (30%), Positives = 235/467 (50%), Gaps = 61/467 (13%)

Query: 40  ANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLD--LEATKARLSSLES 97
           A D  GRC  T  V +P ++ C              RD+ +++L   LE  +    S+E 
Sbjct: 38  AQDPDGRCICT--VVAPEQNLC-------------SRDAKSRQLRQLLEKVQNMSQSIEV 82

Query: 98  LLHQLTLD-QAARPQETQ-EGLQRELGTLRRERDQLETQT-RELETAYSNLLRDKSVLEE 154
           L  +   D Q     ETQ +GL+ +   +  +R  L T+  +EL+     LL    VLE+
Sbjct: 83  LNLRTQRDFQYVLKMETQMKGLKAKFRQIEDDRKTLMTKHFQELKEKMDELLPLIPVLEQ 142

Query: 155 EKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQE 214
            K          A+ +    +E+  L             AV  G +E     +    ++E
Sbjct: 143 YKTD--------AKLITQFKEEIRNLS------------AVLTGIQE----EIGAYDYEE 178

Query: 215 LKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDP 274
           L   +  +             LR       CG+L+ +  P+T++T+ T   ++G WM DP
Sbjct: 179 LHQRVLSLETR----------LRDCMKKLTCGKLMKITGPVTVKTSGT---RFGAWMTDP 225

Query: 275 KPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSL 334
             +    +   W +D+  T+ + V EY  I+ F+ G  S+ + LP     T  VVY+GSL
Sbjct: 226 LASEKNNR--VWYMDSY-TNNKIVREYKSIADFVSGAESRTYNLPFKWAGTNHVVYNGSL 282

Query: 335 YFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYST 394
           YF   +S  +I+Y  +   V A++ +  AG+H  +PY+WGG++DIDL  DE GLW +Y+T
Sbjct: 283 YFNKYQSNIIIKYSFDMGRVLAQRSLEYAGFHNVYPYTWGGFSDIDLMADEIGLWAVYAT 342

Query: 395 DEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYD 454
           ++  G IV+S+LN + LE+ ++W T   K+S   +F+ICGTLY  +S+ +  A V ++Y 
Sbjct: 343 NQNAGNIVISQLNQDTLEVMKSWSTGYPKRSAGESFMICGTLYVTNSHLTG-AKVYYSYS 401

Query: 455 TGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKL 501
           T T   +   IPF N+Y + SM+DYN  ++ L+AW+N + V +++ L
Sbjct: 402 TKTSTYEYTDIPFHNQYFHISMLDYNARDRALYAWNNGHQVLFNVTL 448


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score =  186 bits (471), Expect = 6e-47
 Identities = 93/241 (38%), Positives = 135/241 (56%), Gaps = 16/241 (6%)

Query: 268 GVWMRDPKPTYP---YTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLES 324
           G W +DP        Y   T +R DT+        EY     F+ G P+  + LP  ++ 
Sbjct: 156 GAWCKDPLQASDKIYYMPWTPYRTDTLT-------EYSSKDDFIAGRPTTTYKLPHRVDG 208

Query: 325 TGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVD 384
           TG VVY G+L+F    +R +++++L T     E  I  A YH   PY WGG +DIDLAVD
Sbjct: 209 TGFVVYDGALFFNKERTRNIVKFDLRTRIKSGEAIIANANYHDTSPYRWGGKSDIDLAVD 268

Query: 385 EAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTS 444
           E GLWVIY+T++  G IV+S+LNP  L +E TW+T   K+S +NAF+ICG LY V S   
Sbjct: 269 ENGLWVIYATEQNNGKIVISQLNPYTLRIEGTWDTAYDKRSASNAFMICGILYVVKSVYE 328

Query: 445 ADAT------VNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYD 498
            D        +++ Y+T       + +PF N Y+Y + +DYNP +  L+ W+N ++V Y 
Sbjct: 329 DDDNEATGNKIDYIYNTDQSKDSLVDVPFPNSYQYIAAVDYNPRDNLLYVWNNYHVVKYS 388

Query: 499 I 499
           +
Sbjct: 389 L 389


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score =  177 bits (450), Expect = 2e-44
 Identities = 89/244 (36%), Positives = 137/244 (56%), Gaps = 16/244 (6%)

Query: 266 KYGVWMRDPKPTYP---YTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPL 322
           K G W +DP        +   T +R DT+        EY  +  F     +  + LP  +
Sbjct: 155 KAGAWCKDPLQAADKIYFMPWTPYRTDTL-------IEYASLEDFQNSRQTTTYKLPNRV 207

Query: 323 ESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLA 382
           + TG VVY G+++F    +R +++++L T     E  I  A YH   PY WGG TDIDLA
Sbjct: 208 DGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLA 267

Query: 383 VDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSY 442
           VDE GLWVIY+T++  G IV+S+LNP  L  E TWET   K++ +NAF+ICG LY V S 
Sbjct: 268 VDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSV 327

Query: 443 ------TSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVT 496
                  +   ++++ Y+T     + + +PF N+Y+Y + +DYNP + +L+ W+N  ++ 
Sbjct: 328 YQDNESETGKNSIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILR 387

Query: 497 YDIK 500
           Y ++
Sbjct: 388 YSLE 391


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score =  172 bits (437), Expect = 5e-43
 Identities = 94/264 (35%), Positives = 143/264 (54%), Gaps = 19/264 (7%)

Query: 246 GELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTW---RIDTVGTDVRQVFEYD 302
           G L  V EP +   +E    + G W +DP           W   R DT+        EY 
Sbjct: 142 GTLQKVLEPTSTHESEH---QSGAWCKDPLQAGDRIYVMPWIPYRTDTLT-------EYA 191

Query: 303 LISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPG 362
               ++    +  + LP  ++ TG VVY G++++    +R +++Y+L T     E  I  
Sbjct: 192 SWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINT 251

Query: 363 AGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIR 422
           A YH   PY WGG TDIDLAVDE GLWVIY+T+   G +V+S+LNP  L  E TWET   
Sbjct: 252 ANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYD 311

Query: 423 KQSVANAFIICGTLYTVSS-YTSADA-----TVNFAYDTGTGISKTLTIPFKNRYKYSSM 476
           K+S +NAF++CG LY + S Y   D+      V++A++T     + +++ F N Y++ S 
Sbjct: 312 KRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLTFPNPYQFISS 371

Query: 477 IDYNPLEKKLFAWDNLNMVTYDIK 500
           +DYNP + +L+ W+N  +V Y ++
Sbjct: 372 VDYNPRDNQLYVWNNYFVVRYSLE 395


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score =  172 bits (437), Expect = 5e-43
 Identities = 94/264 (35%), Positives = 143/264 (54%), Gaps = 19/264 (7%)

Query: 246 GELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTW---RIDTVGTDVRQVFEYD 302
           G L  V EP +   +E    + G W +DP           W   R DT+        EY 
Sbjct: 137 GTLQKVLEPTSTHESEH---QSGAWCKDPLQAGDRIYVMPWIPYRTDTLT-------EYA 186

Query: 303 LISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPG 362
               ++    +  + LP  ++ TG VVY G++++    +R +++Y+L T     E  I  
Sbjct: 187 SWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINT 246

Query: 363 AGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIR 422
           A YH   PY WGG TDIDLAVDE GLWVIY+T+   G +V+S+LNP  L  E TWET   
Sbjct: 247 ANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYD 306

Query: 423 KQSVANAFIICGTLYTVSS-YTSADA-----TVNFAYDTGTGISKTLTIPFKNRYKYSSM 476
           K+S +NAF++CG LY + S Y   D+      V++A++T     + +++ F N Y++ S 
Sbjct: 307 KRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLTFPNPYQFISS 366

Query: 477 IDYNPLEKKLFAWDNLNMVTYDIK 500
           +DYNP + +L+ W+N  +V Y ++
Sbjct: 367 VDYNPRDNQLYVWNNYFVVRYSLE 390


>gi|116014339 olfactomedin-like 2A [Homo sapiens]
          Length = 652

 Score =  172 bits (436), Expect = 6e-43
 Identities = 127/422 (30%), Positives = 197/422 (46%), Gaps = 37/422 (8%)

Query: 89  KARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRD 148
           K +L  +E L  +       +P      L ++   +R        +    E    N L+ 
Sbjct: 253 KEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFTYYKAGKQEVTEAVADNTLQG 312

Query: 149 KSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLD 208
            S LE+   ++  E  + +    S+ Q+ A  R  +     D A   P      +T    
Sbjct: 313 TSWLEQLPPKV--EGRSNSAEPNSAEQDEAEPRSSE---RVDLASGTPTSIPATTT---- 363

Query: 209 TLAFQELKSELTEVPASRILK-ESPSGYLRSGEG-DTGC-GELVWVGEPLTLRTAETITG 265
                   +  T  P + +L  E PSG   S +G +  C G L  V  P+   +     G
Sbjct: 364 -------TATTTPTPTTSLLPTEPPSGPEVSSQGREASCEGTLRAVDPPVRHHSY----G 412

Query: 266 KY-GVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLES 324
           ++ G WM+DP         T +           + E+  +  F QG  S ++ LP     
Sbjct: 413 RHEGAWMKDPAARDDRIYVTNYYYGN------SLVEFRNLENFKQGRWSNMYKLPYNWIG 466

Query: 325 TGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVD 384
           TG VVY G+ Y+  A ++ +I+Y+L    V +   +P   Y    P+ W G++DID AVD
Sbjct: 467 TGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVD 526

Query: 385 EAGLWVIYST----DEAKG-AIVLSKLNPENLEL--EQTWETNIRKQSVANAFIICGTLY 437
           E+GLWVIY      DEA+   IVLS+L+P +L +  E TW+T +R+ S  N F++CG LY
Sbjct: 527 ESGLWVIYPAVDDRDEAQPEVIVLSRLDPGDLSVHRETTWKTRLRRNSYGNCFLVCGILY 586

Query: 438 TVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTY 497
            V +Y   +  V +A+DT TG      +PF N + Y++ IDYNP E+ L+AWDN + +TY
Sbjct: 587 AVDTYNQQEGQVAYAFDTHTGTDARPQLPFLNEHAYTTQIDYNPKERVLYAWDNGHQLTY 646

Query: 498 DI 499
            +
Sbjct: 647 TL 648


>gi|46195719 olfactomedin-like 2B [Homo sapiens]
          Length = 750

 Score =  166 bits (419), Expect = 6e-41
 Identities = 90/247 (36%), Positives = 130/247 (52%), Gaps = 12/247 (4%)

Query: 259 TAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHIL 318
           T  T     G WM+DP         T +           + E+  +  F QG  S  + L
Sbjct: 506 TQNTYGRNEGAWMKDPLAKDERIYVTNYYYGNT------LVEFRNLENFKQGRWSNSYKL 559

Query: 319 PRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTD 378
           P     TG VVY+G+ Y+  A +R +I+Y+L    V A   +    Y    P+ W G++D
Sbjct: 560 PYSWIGTGHVVYNGAFYYNRAFTRNIIKYDLKQRYVAAWAMLHDVAYEEATPWRWQGHSD 619

Query: 379 IDLAVDEAGLWVIYSTDEAKG----AIVLSKLNPENL--ELEQTWETNIRKQSVANAFII 432
           +D AVDE GLW+IY   + +G     IVLSKLN  +L  + E TW T +R+    N F+I
Sbjct: 620 VDFAVDENGLWLIYPALDDEGFSQEVIVLSKLNAADLSTQKETTWRTGLRRNFYGNCFVI 679

Query: 433 CGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNL 492
           CG LY V SY   +A +++A+DT T       + F+N Y Y++ IDYNP ++ L+AWDN 
Sbjct: 680 CGVLYAVDSYNQRNANISYAFDTHTNTQIVPRLLFENEYSYTTQIDYNPKDRLLYAWDNG 739

Query: 493 NMVTYDI 499
           + VTY +
Sbjct: 740 HQVTYHV 746


>gi|32313593 olfactomedin 4 precursor [Homo sapiens]
          Length = 510

 Score =  142 bits (359), Expect = 5e-34
 Identities = 90/293 (30%), Positives = 148/293 (50%), Gaps = 12/293 (4%)

Query: 215 LKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTA-ETITGKYGVWMRD 273
           LK++L E  AS+  + +P  +     G  G G +V + +P  ++      +  YG W RD
Sbjct: 219 LKTKLKECEASKD-QNTPVVHPPPTPGSCGHGGVVNISKPSVVQLNWRGFSYLYGAWGRD 277

Query: 274 PKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLEST-----GAV 328
             P +P   +  + +  + TD R +  Y L +         ++I  R L  T     G  
Sbjct: 278 YSPQHP--NKGLYWVAPLNTDGRLLEYYRLYNTLDD---LLLYINARELRITYGQGSGTA 332

Query: 329 VYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGL 388
           VY+ ++Y     +  + R  L T T+   + +P A Y+ +F Y+   + DID AVDE GL
Sbjct: 333 VYNNNMYVNMYNTGNIARVNLTTNTIAVTQTLPNAAYNNRFSYANVAWQDIDFAVDENGL 392

Query: 389 WVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADAT 448
           WVIYST+ + G +V+SKLN   L++  TW T   K S +NAF++CG LY   +  +    
Sbjct: 393 WVIYSTEASTGNMVISKLNDTTLQVLNTWYTKQYKPSASNAFMVCGVLYATRTMNTRTEE 452

Query: 449 VNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKL 501
           + + YDT TG    L I      +    I+YNP ++KL+ +++  ++ YD+ +
Sbjct: 453 IFYYYDTNTGKEGKLDIVMHKMQEKVQSINYNPFDQKLYVYNDGYLLNYDLSV 505


>gi|9910270 olfactomedin-like 3 [Homo sapiens]
          Length = 406

 Score =  125 bits (313), Expect = 1e-28
 Identities = 111/410 (27%), Positives = 181/410 (44%), Gaps = 57/410 (13%)

Query: 115 EGLQRELGTLRRE----RDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRL 170
           E ++R L  L       +DQ      EL    + +L    V E+E++ LR E + ++ R+
Sbjct: 28  EYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKEREALRTEADTISGRV 87

Query: 171 ESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKE 230
           +   +EV  L      +T++ A                 L   E   ++T  P ++    
Sbjct: 88  DRLEREVDYL------ETQNPA-----------------LPCVEFDEKVTGGPGTKGKGR 124

Query: 231 SPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDT 290
               Y    +  T CG  +   +  +++  +   G  G+W +DP        E  + +D 
Sbjct: 125 RNEKY----DMVTDCGYTI--SQVRSMKILKRFGGPAGLWTKDPLGQ----TEKIYVLDG 174

Query: 291 VGTDVRQVFEY--DLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQ---------GA 339
              D   VF    D          S+V + P P   TG +VY G LYF          G 
Sbjct: 175 TQNDTAFVFPRLRDFTLAMAARKASRVRV-PFPWVGTGQLVYGGFLYFARRPPGRPGGGG 233

Query: 340 ESRT---VIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDE 396
           E      +I++ L   TV      P  G     PY     T IDLA DE GLW +Y+T E
Sbjct: 234 EMENTLQLIKFHLANRTVVDSSVFPAEGLIP--PYGLTADTYIDLAADEEGLWAVYATRE 291

Query: 397 AKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTV-SSYTSADATVNFAYD- 454
               + L+KL+P+ L+ EQ W+T   +++   AF+ICGTLY V ++  ++ A +  ++D 
Sbjct: 292 DDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDA 351

Query: 455 TGTGISKTLTIP-FKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSK 503
           +GT   +   +P F  RY   + + YNP E++L+AWD+   + Y +++ K
Sbjct: 352 SGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRK 401


>gi|38348264 olfactomedin-like 1 [Homo sapiens]
          Length = 402

 Score =  117 bits (294), Expect = 2e-26
 Identities = 81/255 (31%), Positives = 125/255 (49%), Gaps = 14/255 (5%)

Query: 256 TLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPS-- 313
           +L+  + +   +G WM+D      Y     + +  +G+    V+E+  I  FM+      
Sbjct: 150 SLKIVKKMMDTHGSWMKDAV----YNSPKVYLL--IGSRNNTVWEFANIRAFMEDNTKPA 203

Query: 314 -KVHILPRPLESTGAVVYSGSLYFQG-AESRTVIRYELNTETVKAEKEIPGAGYHGQFPY 371
            +  IL    + TG V+Y G L+F   A S  +I+Y L   TV+    +PG G      Y
Sbjct: 204 PRKQILTLSWQGTGQVIYKGFLFFHNQATSNEIIKYNLQKRTVEDRMLLPG-GVGRALVY 262

Query: 372 SWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFI 431
                T IDLAVDE GLW I+S       +VL+K+ P  L +E +W+T  R Q    +F+
Sbjct: 263 QHSPSTYIDLAVDEHGLWAIHSGPGTHSHLVLTKIEPGTLGVEHSWDTPCRSQDAEASFL 322

Query: 432 ICGTLYTV-SSYTSADATVNFAYD-TGTGISKTL-TIPFKNRYKYSSMIDYNPLEKKLFA 488
           +CG LY V S+       +   YD  GT   + L  + F  R +  SMI YNP +K+L+A
Sbjct: 323 LCGVLYVVYSTGGQGPHRITCIYDPLGTISEEDLPNLFFPKRPRSHSMIHYNPRDKQLYA 382

Query: 489 WDNLNMVTYDIKLSK 503
           W+  N + Y ++  +
Sbjct: 383 WNEGNQIIYKLQTKR 397


>gi|98986321 gliomedin [Homo sapiens]
          Length = 551

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 75/312 (24%), Positives = 130/312 (41%), Gaps = 27/312 (8%)

Query: 196 PPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPL 255
           PPGSR        ++   +   E   +P    L                   +  +G P+
Sbjct: 252 PPGSRRAKGPRQPSMFNGQCPGETCAIPNDDTLVGKADEKASEHHSPQAESMITSIGNPV 311

Query: 256 -TLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQF------M 308
             L+  ET    +G W+R+       + +  W        V + F   ++ +F      +
Sbjct: 312 QVLKVTET----FGTWIRESANK---SDDRIW--------VTEHFSGIMVKEFKDQPSLL 356

Query: 309 QGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQ 368
            G  + +H LP      G VVY+ SLY+    S T++R+E   ET +  K +  A Y  +
Sbjct: 357 NGSYTFIH-LPYYFHGCGHVVYNNSLYYHKGGSNTLVRFEFGQETSQTLK-LENALYFDR 414

Query: 369 FPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVAN 428
                   T  +LAVDE GLW+IY++     +I++++L+     + Q   T   K    N
Sbjct: 415 KYLFANSKTYFNLAVDEKGLWIIYASSVDGSSILVAQLDERTFSVVQHVNTTYPKSKAGN 474

Query: 429 AFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFA 488
           AFI  G LY      + D  V FA+D   G         +      +M+ YN  ++ L++
Sbjct: 475 AFIARGILYVTD---TKDMRVTFAFDLLGGKQINANFDLRTSQSVLAMLAYNMRDQHLYS 531

Query: 489 WDNLNMVTYDIK 500
           W++ +++ Y ++
Sbjct: 532 WEDGHLMLYPVQ 543


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 7/108 (6%)

Query: 77  DSSTQRLD--LEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQ 134
           D   QRL   LE +  ++  LES L  L ++     Q  Q+ L+ EL    +  +QLE +
Sbjct: 762 DIENQRLQKTLENSNKKIQQLESELQDLEMEN----QTLQKNLE-ELKISSKRLEQLEKE 816

Query: 135 TRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRR 182
            + LE   S L +DK  LE+E KRLRQ+ E     LE ++ ++  L +
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 39/149 (26%), Positives = 70/149 (46%), Gaps = 8/149 (5%)

Query: 33   RTAQLRKAND----QSGRCQYTFSVASPNESSCPEQSQAMSVIHN-LQRDSSTQRLDLEA 87
            +T  L++ N     Q+ + Q   S  +   +S   Q+  + +  + L+ ++ +   + E 
Sbjct: 1089 QTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1148

Query: 88   TKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLR 147
             K+   SL     +L L    +  E  E L  + GTL+     LE + R+LE  Y+ LL+
Sbjct: 1149 LKSLYDSLIKDHEKLELLHERQASE-YESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1207

Query: 148  DKSVLEEEKKRLRQENENLARRLESSSQE 176
             K  LE+ +K L+ E E +   LE+ + E
Sbjct: 1208 QKGQLEDLEKMLKVEQEKML--LENKNHE 1234



 Score = 36.2 bits (82), Expect = 0.072
 Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 24/138 (17%)

Query: 60  SCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQR 119
           S  E S  +S I   +R    +    +    R   LE+ LH L        ++  E LQ+
Sbjct: 595 SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHL--------EKENELLQK 646

Query: 120 ELGTLR----------RERDQLETQTRELET---AYSNLLRDKSVLEEEKKRLRQENENL 166
           ++  L+          +E  +LE + R+L+    ++ NL      LE+E  +L +EN  L
Sbjct: 647 KITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLEL 706

Query: 167 ARRLES---SSQEVARLR 181
            R +ES   +S ++A+L+
Sbjct: 707 RRNVESLKCASMKMAQLQ 724



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 13/98 (13%)

Query: 112 ETQEGLQRELGT----LRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLA 167
           E+++ L  EL      +RR R +LE +T +L      L +    +E E KRL+QEN NL 
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQ----MEIELKRLQQENMNLL 299

Query: 168 RRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTW 205
                S    AR+ R +    R+ A  V     EVS +
Sbjct: 300 -----SDARSARMYRDELDALREKAVRVDKLESEVSRY 332



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 8/103 (7%)

Query: 74   LQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLET 133
            ++R+++T + + +A K +L  LE+  + L     A        LQR+  +L+ +   L+T
Sbjct: 1051 VERNNATLQAEKQALKTQLKQLETQNNNLQAQILA--------LQRQTVSLQEQNTTLQT 1102

Query: 134  QTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQE 176
            Q  +L+   S L    + L  +  +L  +  +L    ES  +E
Sbjct: 1103 QNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE 1145



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 8/119 (6%)

Query: 57  NESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEG 116
           N+S      +  + + +++ ++S + L +E    RLS    +L     ++  + +++ + 
Sbjct: 469 NQSLTKTVEELRTTVDSVEGNAS-KILKMEKENQRLSKKVEILE----NEIVQEKQSLQN 523

Query: 117 LQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQ 175
            Q     L +E+ QLE   + +ET   N  R   +LE+E + L Q   +L +R + S++
Sbjct: 524 CQNLSKDLMKEKAQLE---KTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE 579



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 32/140 (22%), Positives = 63/140 (45%), Gaps = 7/140 (5%)

Query: 82   RLDLEATKARLSSLESLLHQLTLDQAARPQETQEGL-QRELGTLRRERDQLETQTRELET 140
            R +L+  K    +L+    +  + Q++ P   ++   +RE     RE  +++ +  E+E 
Sbjct: 994  RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVER 1053

Query: 141  AYSNLLRDKSVLEEEKKRLRQENENL-ARRLESSSQEVARLRRGQCPQTRDTARAVPPGS 199
              + L  +K  L+ + K+L  +N NL A+ L    Q V+   +    QT++    V    
Sbjct: 1054 NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV---- 1109

Query: 200  REVSTWNLDTLAFQELKSEL 219
             E ST N  + +     ++L
Sbjct: 1110 -ENSTLNSQSTSLMNQNAQL 1128


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 37/108 (34%), Positives = 56/108 (51%), Gaps = 7/108 (6%)

Query: 77  DSSTQRLD--LEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQ 134
           D   QRL   LE +  ++  LES L  L ++     Q  Q+ L+ EL    +  +QLE +
Sbjct: 762 DIENQRLQKTLENSNKKIQQLESELQDLEMEN----QTLQKNLE-ELKISSKRLEQLEKE 816

Query: 135 TRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRR 182
            + LE   S L +DK  LE+E KRLRQ+ E     LE ++ ++  L +
Sbjct: 817 NKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 39/149 (26%), Positives = 70/149 (46%), Gaps = 8/149 (5%)

Query: 33   RTAQLRKAND----QSGRCQYTFSVASPNESSCPEQSQAMSVIHN-LQRDSSTQRLDLEA 87
            +T  L++ N     Q+ + Q   S  +   +S   Q+  + +  + L+ ++ +   + E 
Sbjct: 1088 QTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147

Query: 88   TKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLR 147
             K+   SL     +L L    +  E  E L  + GTL+     LE + R+LE  Y+ LL+
Sbjct: 1148 LKSLYDSLIKDHEKLELLHERQASE-YESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLK 1206

Query: 148  DKSVLEEEKKRLRQENENLARRLESSSQE 176
             K  LE+ +K L+ E E +   LE+ + E
Sbjct: 1207 QKGQLEDLEKMLKVEQEKML--LENKNHE 1233



 Score = 36.2 bits (82), Expect = 0.072
 Identities = 36/138 (26%), Positives = 63/138 (45%), Gaps = 24/138 (17%)

Query: 60  SCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQR 119
           S  E S  +S I   +R    +    +    R   LE+ LH L        ++  E LQ+
Sbjct: 595 SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHL--------EKENELLQK 646

Query: 120 ELGTLR----------RERDQLETQTRELET---AYSNLLRDKSVLEEEKKRLRQENENL 166
           ++  L+          +E  +LE + R+L+    ++ NL      LE+E  +L +EN  L
Sbjct: 647 KITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLEL 706

Query: 167 ARRLES---SSQEVARLR 181
            R +ES   +S ++A+L+
Sbjct: 707 RRNVESLKCASMKMAQLQ 724



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 13/98 (13%)

Query: 112 ETQEGLQRELGT----LRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLA 167
           E+++ L  EL      +RR R +LE +T +L      L +    +E E KRL+QEN NL 
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQ----MEIELKRLQQENMNLL 299

Query: 168 RRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTW 205
                S    AR+ R +    R+ A  V     EVS +
Sbjct: 300 -----SDARSARMYRDELDALREKAVRVDKLESEVSRY 332



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 25/103 (24%), Positives = 49/103 (47%), Gaps = 8/103 (7%)

Query: 74   LQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLET 133
            ++R+++T + + +A K +L  LE+  + L     A        LQR+  +L+ +   L+T
Sbjct: 1050 VERNNATLQAEKQALKTQLKQLETQNNNLQAQILA--------LQRQTVSLQEQNTTLQT 1101

Query: 134  QTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQE 176
            Q  +L+   S L    + L  +  +L  +  +L    ES  +E
Sbjct: 1102 QNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKE 1144



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 27/119 (22%), Positives = 58/119 (48%), Gaps = 8/119 (6%)

Query: 57  NESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEG 116
           N+S      +  + + +++ ++S + L +E    RLS    +L     ++  + +++ + 
Sbjct: 469 NQSLTKTVEELRTTVDSVEGNAS-KILKMEKENQRLSKKVEILE----NEIVQEKQSLQN 523

Query: 117 LQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQ 175
            Q     L +E+ QLE   + +ET   N  R   +LE+E + L Q   +L +R + S++
Sbjct: 524 CQNLSKDLMKEKAQLE---KTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE 579



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 32/140 (22%), Positives = 63/140 (45%), Gaps = 7/140 (5%)

Query: 82   RLDLEATKARLSSLESLLHQLTLDQAARPQETQEGL-QRELGTLRRERDQLETQTRELET 140
            R +L+  K    +L+    +  + Q++ P   ++   +RE     RE  +++ +  E+E 
Sbjct: 993  RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVER 1052

Query: 141  AYSNLLRDKSVLEEEKKRLRQENENL-ARRLESSSQEVARLRRGQCPQTRDTARAVPPGS 199
              + L  +K  L+ + K+L  +N NL A+ L    Q V+   +    QT++    V    
Sbjct: 1053 NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV---- 1108

Query: 200  REVSTWNLDTLAFQELKSEL 219
             E ST N  + +     ++L
Sbjct: 1109 -ENSTLNSQSTSLMNQNAQL 1127


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 3/127 (2%)

Query: 58  ESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSL---ESLLHQLTLDQAARPQETQ 114
           E   PE     S +  LQ +++  R +LE+   +L +      +L  L   Q  R +E +
Sbjct: 146 EPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQE 205

Query: 115 EGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSS 174
           E L+ +   LR + ++L  Q   L      L   +  L E+++RLR+  E L  + E   
Sbjct: 206 ERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLC 265

Query: 175 QEVARLR 181
           ++  RLR
Sbjct: 266 EQEERLR 272



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 10/119 (8%)

Query: 63  EQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELG 122
           E +Q +S+++  Q +       L   + RL   E  L +    Q  R  E +E L+ +  
Sbjct: 185 ENNQMLSLLNRRQEER------LREQEERLREQEERLRE----QEERLCEQEERLREQEE 234

Query: 123 TLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLR 181
            LR + ++L  Q   L      L   +  L E+++RLR++ E L  + E   ++  RLR
Sbjct: 235 RLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR 293



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 34/127 (26%), Positives = 56/127 (44%), Gaps = 7/127 (5%)

Query: 58  ESSCPEQSQAMSVIHNLQRDSSTQRL-DLEATKARLSSLESLLHQLTLDQAARPQ---ET 113
           +SS    SQ    I++L R S  ++  ++   +    SL  L +Q     A  P      
Sbjct: 99  DSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSK 158

Query: 114 QEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESS 173
            E LQ E   LR+E   LE+  R+L+    N      +   +++RLR++ E L  + E  
Sbjct: 159 VEQLQDETNHLRKE---LESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERL 215

Query: 174 SQEVARL 180
            ++  RL
Sbjct: 216 REQEERL 222


>gi|112420968 coiled-coil domain containing 158 [Homo sapiens]
          Length = 1113

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 39/159 (24%), Positives = 67/159 (42%), Gaps = 7/159 (4%)

Query: 30  VGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVI-HNLQRDSSTQRLDLEAT 88
           V A + +LR   D         +    + S     S+   V+  N +  S    +     
Sbjct: 638 VNAGSERLRAVKDIKQERDQLLNEVKTSRSELNNLSEEYEVLKRNFRNKSEEMEMTTNKL 697

Query: 89  KARLSSLESLLHQL--TLDQA----ARPQETQEGLQRELGTLRRERDQLETQTRELETAY 142
           K +L S +S L Q   TL           +   G+Q+++   R + D L+++ + LE A 
Sbjct: 698 KMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAM 757

Query: 143 SNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLR 181
           +N  ++K  L+EEK +L QE   +A      + E+  LR
Sbjct: 758 TNANKEKHFLKEEKSKLSQELSTVATEKNKMAGELEVLR 796



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 39/145 (26%), Positives = 63/145 (43%), Gaps = 10/145 (6%)

Query: 48  QYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLT--LD 105
           ++   +    E +   +SQA S+   ++      R        +LS LES + QL   L 
Sbjct: 275 EHEVEITGLTEKASSARSQANSIQSQMEIIQEQARNQNSMYMRQLSDLESTVSQLRSELR 334

Query: 106 QAARPQETQ-EGLQR-------ELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKK 157
           +A R  E + E L++       EL   R ERDQ   ++  L+     LL D    E+E  
Sbjct: 335 EAKRMYEDKTEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELS 394

Query: 158 RLRQENENLARRLESSSQEVARLRR 182
             +++N+ L  R   +S  +  LRR
Sbjct: 395 LEKEQNKRLWDRDTGNSITIDHLRR 419


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 3/115 (2%)

Query: 69  SVIHNLQRDSSTQRLDLEATKARLSSL---ESLLHQLTLDQAARPQETQEGLQRELGTLR 125
           SV+  LQ ++   R ++E  + +L S       L  L+ +Q  R QE +E L+ +     
Sbjct: 295 SVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354

Query: 126 RERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
           RE+++L  Q   L      L      L ++++RLR++ E L +  E   ++  RL
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRL 409



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 11/105 (10%)

Query: 91  RLSSLESLLHQLTLDQAARPQ-------ETQEGLQRELGTLRRERDQLETQTR---ELET 140
           R+  LE  L +L    A  P           E LQ E   LR+E + LE + +   E   
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326

Query: 141 AYSNLLRD-KSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQ 184
           A S L ++ K  L+E+++ LR++     R  E   ++  RLR  Q
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 39/167 (23%), Positives = 68/167 (40%), Gaps = 33/167 (19%)

Query: 39  KANDQSGRCQYTFS-VASPNESSCPEQSQAMSVIHNLQ-RDSSTQRLDLEATKAR----- 91
           ++ D +GR QY+   +     + C   +Q      +   R++  QR   +  K R     
Sbjct: 154 ESKDLAGRLQYSLQHIQELERALCAVSTQQQEEDRSSSCREAVLQRRLQQTIKERALLNA 213

Query: 92  -LSSLESLLHQLTLD----------QAARPQETQEGLQRELGTLRRERDQLETQTRELET 140
            ++ +   L Q+ L+          + AR QE    +  E  TL+ E+ +   + +ELE 
Sbjct: 214 HVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELER 273

Query: 141 AYSNLLRDKS---------------VLEEEKKRLRQENENLARRLES 172
           + S L    +                L++E K LRQE E L  +L+S
Sbjct: 274 SLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQS 320


>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
           isoform 1 [Homo sapiens]
          Length = 693

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 3/115 (2%)

Query: 69  SVIHNLQRDSSTQRLDLEATKARLSSL---ESLLHQLTLDQAARPQETQEGLQRELGTLR 125
           SV+  LQ ++   R ++E  + +L S       L  L+ +Q  R QE +E L+ +     
Sbjct: 295 SVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354

Query: 126 RERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
           RE+++L  Q   L      L      L ++++RLR++ E L +  E   ++  RL
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRL 409



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 11/105 (10%)

Query: 91  RLSSLESLLHQLTLDQAARPQ-------ETQEGLQRELGTLRRERDQLETQTR---ELET 140
           R+  LE  L +L    A  P           E LQ E   LR+E + LE + +   E   
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326

Query: 141 AYSNLLRD-KSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQ 184
           A S L ++ K  L+E+++ LR++     R  E   ++  RLR  Q
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 39/169 (23%), Positives = 64/169 (37%), Gaps = 37/169 (21%)

Query: 39  KANDQSGRCQYTF----------SVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEAT 88
           ++ D +GR QY+           S  S  +      S     +  LQR       +    
Sbjct: 154 ESKDLAGRLQYSLQRIQELERALSAVSTQQQEEDRSSSCREAV--LQRRLQQTIKERALL 211

Query: 89  KARLSSLESLLHQLTLD----------QAARPQETQEGLQRELGTLRRERDQLETQTREL 138
            A ++ +   L Q+ L+          + AR QE    +  E  TL+ E+ +   + +EL
Sbjct: 212 NAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQEL 271

Query: 139 ETAYSNLLRDKS---------------VLEEEKKRLRQENENLARRLES 172
           E + S L    +                L++E K LRQE E L  +L+S
Sbjct: 272 ERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQS 320


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 39/169 (23%), Positives = 73/169 (43%), Gaps = 15/169 (8%)

Query: 35  AQLRKANDQSGRCQYTFSVASPNESSCPE---QSQAMSVIHNLQRDSSTQ-----RLDLE 86
           AQ    +DQS  C+    +    ++   E       MSV+ N  +   T+     R +L 
Sbjct: 200 AQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELS 259

Query: 87  ATKARLSSLESLLHQ-------LTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELE 139
             + R+  LE+LL Q         L +    Q+T + LQ E     ++ +QLE + +++ 
Sbjct: 260 DYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDIN 319

Query: 140 TAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQT 188
              S+   D+ +L  E+++L  E   +    E+   E ++L+     Q+
Sbjct: 320 KKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQS 368



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 33/122 (27%), Positives = 61/122 (50%), Gaps = 16/122 (13%)

Query: 73   NLQRDSSTQRLDLEATKARLSSLESLLHQLTLD------QAARPQETQEG--LQRELGTL 124
            N +  S T+++D + +K  +  L  ++ Q  L+      + +    TQ+   LQ++L   
Sbjct: 1036 NEKNISLTKQID-QLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAY 1094

Query: 125  RRERDQ----LETQTRE---LETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEV 177
              ER++    L  +TRE   L+T Y  ++   +  E    +L+ EN+ L+ R ESS Q++
Sbjct: 1095 AMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDM 1154

Query: 178  AR 179
             R
Sbjct: 1155 FR 1156



 Score = 32.7 bits (73), Expect = 0.79
 Identities = 32/152 (21%), Positives = 66/152 (43%), Gaps = 13/152 (8%)

Query: 30   VGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATK 89
            V A+ A L K  D++ +    F      ESS   Q      I NL R    + ++++A  
Sbjct: 1126 VAAKEAALIKLQDENKKLSTRF------ESS--GQDMFRETIQNLSRIIREKDIEIDALS 1177

Query: 90   ARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDK 149
             +  +L ++L   +    A    + +        L +ERD+L+ Q +++E     ++   
Sbjct: 1178 QKCQTLLAVLQTSSTGNEAGGVNSNQ-----FEELLQERDKLKQQVKKMEEWKQQVMTTV 1232

Query: 150  SVLEEEKKRLRQENENLARRLESSSQEVARLR 181
              ++ E  +L++E   L  ++   S   ++L+
Sbjct: 1233 QNMQHESAQLQEELHQLQAQVLVDSDNNSKLQ 1264



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 39/142 (27%), Positives = 60/142 (42%), Gaps = 21/142 (14%)

Query: 71  IHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQ-EGLQRELGTLRRERD 129
           I  L+++      D + TK  LSS  SL  Q  L Q    +E   E L+     L+ E D
Sbjct: 775 IAELKKNIEQMDTDHKETKDVLSS--SLEEQKQLTQLINKKEIFIEKLKERSSKLQEELD 832

Query: 130 QLETQTRELETAYSNLLRDKSVLE---EEKKR----LRQENENLARRLESSSQEVARLRR 182
           +           YS  LR   +L    EEK R    +++EN +L   LE   +E +R   
Sbjct: 833 K-----------YSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAP 881

Query: 183 GQCPQTRDTARAVPPGSREVST 204
              P+T D+   +     +++T
Sbjct: 882 VADPKTLDSVTELASEVSQLNT 903



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 25/119 (21%), Positives = 54/119 (45%), Gaps = 15/119 (12%)

Query: 63  EQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELG 122
           +Q++  S+I  L++D       L   K R+  LE     +T +   + ++    +Q E+ 
Sbjct: 521 QQNEGDSIISKLKQD-------LNDEKKRVHQLEDDKMDITKELDVQKEKL---IQSEVA 570

Query: 123 TLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLR 181
                 + L    ++LE    NL+   +  +E    +++EN  L   +  + +E++R+R
Sbjct: 571 L-----NDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIR 624


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 49/192 (25%), Positives = 85/192 (44%), Gaps = 31/192 (16%)

Query: 57  NESSCPEQSQAMSVIHNLQRDSST-----QRLDLEATKARLSSLESLLHQLTLDQAARPQ 111
           NES   ++     ++  L+ + S      ++ + EAT AR    +  L +L L+Q    Q
Sbjct: 745 NESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATVAREE--QERLEELRLEQEVARQ 802

Query: 112 ----------ETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQ 161
                     + QE L+++L TLR ER QL+ Q  +L        R  S  E+E ++ R+
Sbjct: 803 GLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS-------RQLSGREQELEQARR 855

Query: 162 ENENLARRLESSSQE---VARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQ----E 214
           E +     LE +++E   +A+   G   Q     R     S E +   L+  A +    E
Sbjct: 856 EAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKEALEGSLFE 915

Query: 215 LKSELTEVPASR 226
           ++ +L ++ A R
Sbjct: 916 VQRQLAQLEARR 927



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 43/151 (28%), Positives = 63/151 (41%), Gaps = 26/151 (17%)

Query: 52   SVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAA--- 108
            S A    SS  EQ Q +        D   QR++ E    +L  L  +L Q    +AA   
Sbjct: 1778 SEARKQSSSLGEQVQTL---RGEVADLELQRVEAEG---QLQQLREVLRQRQEGEAAALN 1831

Query: 109  ---RPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVL------------- 152
               + Q+ +  LQ  LG+L+R   QLE + RE+E +   L +D+  L             
Sbjct: 1832 TVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLR 1891

Query: 153  -EEEKKRLRQENENLARRLESSSQEVARLRR 182
              E+  RL  E   L R L  +  E+A  +R
Sbjct: 1892 SHEDTVRLSAEKGRLDRTLTGAELELAEAQR 1922



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 37/151 (24%), Positives = 61/151 (40%), Gaps = 12/151 (7%)

Query: 55  SPNESSCP--EQSQAMSVIHNLQRDSSTQRLDL----EATKARLSSLESLLHQLTLDQAA 108
           SP     P    S  +++IH+       Q  D+    EA++  L +L   L     ++ A
Sbjct: 506 SPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRA 565

Query: 109 RPQETQ------EGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQE 162
             ++ Q      +G  +     +RE  +L +    L    SNL     V +++ + LRQE
Sbjct: 566 LEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQE 625

Query: 163 NENLARRLESSSQEVARLRRGQCPQTRDTAR 193
            E L    E   ++  RL   Q    +D AR
Sbjct: 626 REKLQAAQEELRRQRDRLEEEQEDAVQDGAR 656



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 21/156 (13%)

Query: 71   IHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQ 130
            +  LQR+      +LEA +A+   L+S L +   +  AR +  +E L  E+  L++ERD+
Sbjct: 995  LQRLQREKEAAWRELEAERAQ---LQSQLQREQEELLARLEAEKEELSEEIAALQQERDE 1051

Query: 131  LETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRR-GQCPQTR 189
                   L  A S   +  S+ E EK  L ++       L + S E+ R +R  Q  Q +
Sbjct: 1052 ------GLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQ 1105

Query: 190  DTARAVPPGSREVSTWNLDTLAFQELKSELTEVPAS 225
            D            ST N  T   ++L+++  E  A+
Sbjct: 1106 DR-----------STVNALTSELRDLRAQREEAAAA 1130



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 7/116 (6%)

Query: 67  AMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRR 126
           AM    + QR+    R   E      S+L   L Q+   QA   ++ +E LQ     LRR
Sbjct: 580 AMQAHEDAQREVQRLRSANELLSREKSNLAHSL-QVAQQQAEELRQEREKLQAAQEELRR 638

Query: 127 ERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQ---ENENLARRLESSSQEVAR 179
           +RD+LE    E E A  +  R +  LE   ++L Q   +   LA+ L    + ++R
Sbjct: 639 QRDRLE---EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSR 691



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 38/182 (20%), Positives = 80/182 (43%), Gaps = 23/182 (12%)

Query: 63   EQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQE---TQEGLQR 119
            E+ QA+S+  + +   S +   L  T+  L+++   + +   D  +R ++   T   L  
Sbjct: 1059 EKQQALSLKESEKTALSEK---LMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTS 1115

Query: 120  ELGTLRRERDQ-----------LETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLAR 168
            EL  LR +R++           L+ Q R+L     + LR+   L  + + L    + L R
Sbjct: 1116 ELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRR 1175

Query: 169  RLESSSQEVARLRRGQCPQTRDTA---RAVPPGSREVSTWNLDTLAFQELKSELTEVPAS 225
             L  + +++   + G+  Q ++     R++  G++E           +EL+S + +  + 
Sbjct: 1176 ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSN---EELRSAVKKAESE 1232

Query: 226  RI 227
            RI
Sbjct: 1233 RI 1234



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 12/101 (11%)

Query: 105 DQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQ--- 161
           ++A R +  +E L+  L  ++R+  QLE +  +LE     LL  K  L  E   LRQ   
Sbjct: 897 EEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQII 956

Query: 162 --------ENENLARRLESSSQEV-ARLRRGQCPQTRDTAR 193
                   + E +A++L  + +E  A LR  +     D  R
Sbjct: 957 ATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQR 997



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 3/117 (2%)

Query: 76   RDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGT-LRRERDQLETQ 134
            ++    R   E  ++ +   ES   +++L  A   +E +  L  E  T + +E  +L T 
Sbjct: 1210 KEREALRRSNEELRSAVKKAES--ERISLKLANEDKEQKLALLEEARTAVGKEAGELRTG 1267

Query: 135  TRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDT 191
             +E+E +     R+   L  + K L  EN  L R L      +A   R +    R+T
Sbjct: 1268 LQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRET 1324



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 41/171 (23%), Positives = 68/171 (39%), Gaps = 20/171 (11%)

Query: 33   RTAQLRKANDQSGRCQYTFSVA---SPNESSCPEQSQAMSVIHNLQRDSSTQR----LDL 85
            R AQ R+  D+S     T  +    +  E +    +Q +  +    RD   QR     + 
Sbjct: 1097 RDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREA 1156

Query: 86   EATKARLSSLESL---LHQLTLDQAARPQETQEGLQ---RELGTLRR-------ERDQLE 132
            E  + +L  LE     L +  L+   + +E+QEG +   +E G LRR       ER+ L 
Sbjct: 1157 EELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALR 1216

Query: 133  TQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRG 183
                EL +A      ++  L+   +   Q+   L     +  +E   LR G
Sbjct: 1217 RSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTG 1267



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 28/111 (25%), Positives = 53/111 (47%), Gaps = 6/111 (5%)

Query: 76  RDSSTQRLDLEATKARLSSLES----LLHQLTLDQAARPQET--QEGLQRELGTLRRERD 129
           +D +  R +LE +  +L  LE     L  +L   + A  + T  ++ LQ E   +     
Sbjct: 652 QDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALT 711

Query: 130 QLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
           + E    ELE + + L  +++ L++   +L   NE+LA+     ++ VA+L
Sbjct: 712 KAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQL 762



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 18/167 (10%)

Query: 55   SPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQ-ET 113
            SP+   C   SQ  S         ++  LD EA +    +L   L +L   Q  R +  T
Sbjct: 1476 SPSTLECSPGSQPPSP--GPATSPASPDLDPEAVRG---ALREFLQELRSAQRERDELRT 1530

Query: 114  Q-EGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLES 172
            Q   L R+L  +  ERD   ++ R+L+         K+V E E+ R   +      + E 
Sbjct: 1531 QTSALNRQLAEMEAERDSATSRARQLQ---------KAVAESEEARRSVDGRLSGVQAEL 1581

Query: 173  SSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSEL 219
            + QE + +RR +  + R T   V    R +     +  A QE  S++
Sbjct: 1582 ALQEES-VRRSE-RERRATLDQVATLERSLQATESELRASQEKISKM 1626


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 12/154 (7%)

Query: 38  RKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLES 97
           RK   +    +Y +S +   E   PEQ    S I N+  +S+ +R  L   +      E+
Sbjct: 310 RKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEA 369

Query: 98  LLHQLTL-DQAARPQETQEGL-----QRELGTLRRERDQLETQTRELETAYSNLLRDKSV 151
           L  Q  L +Q  R QE  +       Q+ +   + +R +LE Q R    A     R++  
Sbjct: 370 LRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRR 429

Query: 152 LEEEKKR------LRQENENLARRLESSSQEVAR 179
            E+E+KR       R++ E   RR E   + V R
Sbjct: 430 REQEEKRRLEELERRRKEEEERRRAEEEKRRVER 463


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 12/154 (7%)

Query: 38  RKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLES 97
           RK   +    +Y +S +   E   PEQ    S I N+  +S+ +R  L   +      E+
Sbjct: 310 RKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEA 369

Query: 98  LLHQLTL-DQAARPQETQEGL-----QRELGTLRRERDQLETQTRELETAYSNLLRDKSV 151
           L  Q  L +Q  R QE  +       Q+ +   + +R +LE Q R    A     R++  
Sbjct: 370 LRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRR 429

Query: 152 LEEEKKR------LRQENENLARRLESSSQEVAR 179
            E+E+KR       R++ E   RR E   + V R
Sbjct: 430 REQEEKRRLEELERRRKEEEERRRAEEEKRRVER 463


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 12/154 (7%)

Query: 38  RKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLES 97
           RK   +    +Y +S +   E   PEQ    S I N+  +S+ +R  L   +      E+
Sbjct: 310 RKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEA 369

Query: 98  LLHQLTL-DQAARPQETQEGL-----QRELGTLRRERDQLETQTRELETAYSNLLRDKSV 151
           L  Q  L +Q  R QE  +       Q+ +   + +R +LE Q R    A     R++  
Sbjct: 370 LRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRR 429

Query: 152 LEEEKKR------LRQENENLARRLESSSQEVAR 179
            E+E+KR       R++ E   RR E   + V R
Sbjct: 430 REQEEKRRLEELERRRKEEEERRRAEEEKRRVER 463


>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
           sapiens]
          Length = 693

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 3/115 (2%)

Query: 69  SVIHNLQRDSSTQRLDLEATKARLSSL---ESLLHQLTLDQAARPQETQEGLQRELGTLR 125
           SV+  LQ ++   R ++E  + +L S       L  L+ +Q  R QE +E L+ +     
Sbjct: 295 SVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRV 354

Query: 126 RERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
           RE+++L  Q   L      L      L ++++RLR++ E L +  E   ++  RL
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRL 409



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 11/105 (10%)

Query: 91  RLSSLESLLHQLTLDQAARPQ-------ETQEGLQRELGTLRRERDQLETQTR---ELET 140
           R+  LE  L +L    A  P           E LQ E   LR+E + LE + +   E   
Sbjct: 267 RIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326

Query: 141 AYSNLLRD-KSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQ 184
           A S L ++ K  L+E+++ LR++     R  E   ++  RLR  Q
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQ 371



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 39/167 (23%), Positives = 68/167 (40%), Gaps = 33/167 (19%)

Query: 39  KANDQSGRCQYTFS-VASPNESSCPEQSQAMSVIHNLQ-RDSSTQRLDLEATKAR----- 91
           ++ D +GR QY+   +     + C   +Q      +   R++  QR   +  K R     
Sbjct: 154 ESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNA 213

Query: 92  -LSSLESLLHQLTLD----------QAARPQETQEGLQRELGTLRRERDQLETQTRELET 140
            ++ +   L Q+ L+          + AR QE    +  E  TL+ E+ +   + +ELE 
Sbjct: 214 HVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELER 273

Query: 141 AYSNLLRDKS---------------VLEEEKKRLRQENENLARRLES 172
           + S L    +                L++E K LRQE E L  +L+S
Sbjct: 274 SLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQS 320


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
           sapiens]
          Length = 1478

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 43/153 (28%), Positives = 71/153 (46%), Gaps = 21/153 (13%)

Query: 40  ANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLL 99
           A+D  GR +   S A+       E+ QA      L+R+ +      E  + + + LE L+
Sbjct: 382 ASDTKGRQEPIPSDAAQEMQELGEKLQA------LERERTKVE---EVNRQQSAQLEQLV 432

Query: 100 HQLTLDQAARPQ-----ETQEGLQRELGTLRRERDQLETQTREL-------ETAYSNLLR 147
            +L L + AR       +    LQ EL    +E DQL  + +EL       E   + L R
Sbjct: 433 KELQLKEDARASLERLVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRR 492

Query: 148 DKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
           +K   +EEK+ L QE  +L R+L+    ++A++
Sbjct: 493 EKKQQQEEKELLEQEVRSLTRQLQFLETQLAQV 525



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 41/154 (26%), Positives = 74/154 (48%), Gaps = 12/154 (7%)

Query: 75   QRDSSTQRLDLEATKARLSSLESLLHQLTLDQA---ARPQETQEGLQRELGTLRRER--D 129
            QR+   + L  E ++A+ SS E+ L    L +    A     + G+Q    T+ +ER  +
Sbjct: 865  QREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEE 924

Query: 130  QLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL--RRGQCPQ 187
             L    +EL+ A     R++  LE +   L+QE E+L  +L+++      L   + Q  Q
Sbjct: 925  ALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQ 984

Query: 188  TRDTARAVPPGSREVSTWNLDTLAFQELKSELTE 221
                A+++    +E +   L+TL FQ L +E+ +
Sbjct: 985  AEQRAQSL----QEAAHQELNTLKFQ-LSAEIMD 1013



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 32/98 (32%), Positives = 52/98 (53%), Gaps = 15/98 (15%)

Query: 85  LEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSN 144
           L+   A  SS E  L +L  ++  + QE +E L++E+ +L R+   LETQ  ++    S+
Sbjct: 473 LQELLAHTSSWEEELAELRREKKQQ-QEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSD 531

Query: 145 LLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRR 182
           L       EE+KK+L Q+ ++L       SQ+V  L R
Sbjct: 532 L-------EEQKKQLIQDKDHL-------SQQVGMLER 555



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 42/191 (21%), Positives = 73/191 (38%), Gaps = 34/191 (17%)

Query: 58   ESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGL 117
            E++  E+      +  LQ++  + +  L+A KA   SL  L  QL   +  R Q  QE  
Sbjct: 938  EAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQ-RAQSLQEAA 996

Query: 118  QRELGTLRRE----------------------RDQLETQTRELETAYSNLLRDKSVLEEE 155
             +EL TL+ +                      R QLE Q R+L+ A           EE 
Sbjct: 997  HQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAA-----------EEA 1045

Query: 156  KKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQEL 215
             ++L+    ++  +L  +S  +A  +     + ++ A       R        T   QE 
Sbjct: 1046 VEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQKELEKATTKIQEY 1105

Query: 216  KSELTEVPASR 226
             ++L +   +R
Sbjct: 1106 YNKLCQEVTNR 1116



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 23/119 (19%), Positives = 53/119 (44%), Gaps = 3/119 (2%)

Query: 57   NESSCPEQSQAMSVIHNLQRDSST---QRLDLEATKARLSSLESLLHQLTLDQAARPQET 113
            +E +  E ++    +H    D++    Q   L   K R+    +   Q   D        
Sbjct: 884  SEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASRE 943

Query: 114  QEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLES 172
            +EGL+R++  L++E++ L+ + +  + A  +L   ++ L + ++R +   E   + L +
Sbjct: 944  REGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNT 1002


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 38/117 (32%), Positives = 54/117 (46%), Gaps = 8/117 (6%)

Query: 60  SCPEQSQAMSVIHNLQRDSSTQRLDLEATKA--RLSSLESLLHQL--TLDQAARPQETQE 115
           S  E+SQ  S       +   + L    T+A  +LS LE    QL   L+QA    E  E
Sbjct: 572 SLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERAE 631

Query: 116 GLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLES 172
            L+REL  L+ E  +L  +   LETA   +      LE E + L+ EN  L + L++
Sbjct: 632 KLERELQRLQEENGRLARKVTSLETATEKV----EALEHESQGLQLENRTLRKSLDT 684



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/165 (29%), Positives = 78/165 (47%), Gaps = 35/165 (21%)

Query: 85  LEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRE---LETA 141
           LE++  +  +LES L +L  ++ A        L+R+L  LR    QLE   ++   LE  
Sbjct: 775 LESSSHKTQTLESELGELEAERQA--------LRRDLEALRLANAQLEGAEKDRKALEQE 826

Query: 142 YSNLLRDKSVLEEEKKRLRQENENLARRLESSS--------------QEVARLR--RGQC 185
            + L +DK +LE+E KRL Q+ E     L+ S+              +E+AR R   G+ 
Sbjct: 827 VAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKL 886

Query: 186 PQ----TRDTARAVPPGSREVSTWN----LDTLAFQELKSELTEV 222
            +     RD  + V   +R ++T      L+ L  Q+L SEL ++
Sbjct: 887 KELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKL 931



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 4/142 (2%)

Query: 43   QSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQR--DSSTQRLDLEATKARLSSLESLLH 100
            Q+ + Q   S  S   ++   Q   +   H  +   + S QR   + T A  + L+   H
Sbjct: 1114 QTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAAYEALLQDHEH 1173

Query: 101  QLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLR 160
              TL +  R     E L R+   L+     LE + +EL   + ++L+ K+ LEE +K L 
Sbjct: 1174 LGTLHE--RQSAEYEALIRQHSCLKTLHRNLELEHKELGERHGDMLKRKAELEEREKVLT 1231

Query: 161  QENENLARRLESSSQEVARLRR 182
             E E L +   +++  +   +R
Sbjct: 1232 TEREALQQEQRTNALAMGENQR 1253



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 41/157 (26%), Positives = 71/157 (45%), Gaps = 17/157 (10%)

Query: 30  VGARTAQLRKANDQSGRCQYTF-----SVASPNESSCPEQSQAMSVIHNLQRDSSTQRLD 84
           +G    QL K  D S   + +F       AS       +++Q++       RD+S   L 
Sbjct: 432 LGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDAS---LV 488

Query: 85  LEATKARLSSLESLLHQLTLD------QAARPQETQEGLQRELGTLRRERDQLETQTREL 138
           LE +  +   LE   HQL+        Q  R +++ + L+     L RE++QL++   ++
Sbjct: 489 LEESGLKCGELEKENHQLSKKIEKLQTQLEREKQSNQDLETLSEELIREKEQLQS---DM 545

Query: 139 ETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQ 175
           ET  ++  R    LE+EK  L +   +L  R + SS+
Sbjct: 546 ETLKADKARQIKDLEQEKDHLNRAMWSLRERSQVSSE 582



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 18/147 (12%)

Query: 85  LEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSN 144
           L+    RL+   + L   T    A   E+Q GLQ E  TLR+  D L+  + +LE     
Sbjct: 640 LQEENGRLARKVTSLETATEKVEALEHESQ-GLQLENRTLRKSLDTLQNVSLQLE----G 694

Query: 145 LLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVST 204
           L RD   L+ E   LR+    L   +  +S ++A++ R      R+         +E   
Sbjct: 695 LERDNKQLDAENLELRR----LVETMRFTSTKLAQMERENQQLERE---------KEELR 741

Query: 205 WNLDTLAFQELKSELTEVPASRILKES 231
            N+D L     KSE  E+    +  E+
Sbjct: 742 KNVDLLKALGKKSERLELSYQSVSAEN 768



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 26/112 (23%), Positives = 49/112 (43%), Gaps = 9/112 (8%)

Query: 74   LQRDSSTQRLDL---EATKARLSSLESLLHQLTLDQAARPQETQE------GLQRELGTL 124
            LQ++  T  L +   +  +  L  +  L HQL  +       T+E        Q EL   
Sbjct: 1237 LQQEQRTNALAMGENQRLRGELDRVNFLHHQLKGEYEELHAHTKELKTSLNNAQLELNRW 1296

Query: 125  RRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQE 176
            +   D+L+ Q + ++ + + L     +L   K  L +EN +L  +++  SQ+
Sbjct: 1297 QARFDELKEQHQTMDISLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLSQQ 1348


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 3/115 (2%)

Query: 69  SVIHNLQRDSSTQRLDLEATKARLSSL---ESLLHQLTLDQAARPQETQEGLQRELGTLR 125
           SV+  LQ ++   R ++E  + +L S       L  L+ +Q  R QE +E L+ +     
Sbjct: 295 SVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRV 354

Query: 126 RERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
           RE+++L  Q   L      L      L ++++RLR++ E L +  E   ++  RL
Sbjct: 355 REQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRL 409



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 39/170 (22%)

Query: 39  KANDQSGRCQYTF-----------SVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEA 87
           ++ D +GR QY+            +V++  +      S   +V+H   + +  +R  L A
Sbjct: 154 ESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLHRRLQQTIKERALLNA 213

Query: 88  TKARLSSLESLLHQLTLD----------QAARPQETQEGLQRELGTLRRERDQLETQTRE 137
               ++ +   L Q+ L+          + AR QE    +  E  TL+ E+ +   + +E
Sbjct: 214 ---HVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQE 270

Query: 138 LETAYSNLLRDKS---------------VLEEEKKRLRQENENLARRLES 172
           LE + S L    +                L++E K LRQE E L  +L+S
Sbjct: 271 LERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQS 320



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 11/105 (10%)

Query: 91  RLSSLESLLHQLTLDQAARPQ-------ETQEGLQRELGTLRRERDQLETQTR---ELET 140
           R+  LE  L +L    A  P           E LQ E   LR+E + LE + +   E   
Sbjct: 267 RIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326

Query: 141 AYSNLLRD-KSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQ 184
           A S L ++ K  L+E+++ LR++     R  E   ++  RLR  Q
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQ 371


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/193 (23%), Positives = 80/193 (41%), Gaps = 14/193 (7%)

Query: 36   QLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSL 95
            +L KA +   R +    +    + +  E  QA       Q +S+  ++ LE  K R+S L
Sbjct: 872  ELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLL 931

Query: 96   ESLLHQLTLDQAARPQETQEGLQRELGTLRRERD--------QLETQTRELETAYSNLLR 147
            E+LL   T  + A   +  E L++++   + +          QL+   REL+ A      
Sbjct: 932  ETLLQ--TQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRD 989

Query: 148  DKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNL 207
            D + L+EE   L Q+  +L +++E    ++      Q    R   + V    RE   +N 
Sbjct: 990  DLAALQEESSSLLQDKMDLQKQVEDLKSQLV----AQDDSQRLVEQEVQEKLRETQEYNR 1045

Query: 208  DTLAFQELKSELT 220
                 +  K+ LT
Sbjct: 1046 IQKELEREKASLT 1058



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 32/120 (26%), Positives = 58/120 (48%), Gaps = 11/120 (9%)

Query: 63  EQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELG 122
           +  +A++++ ++         DL    A      +LL Q    Q  + +E  + L++ L 
Sbjct: 383 DADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQ----QHDQWEEEGKALRQRLQ 438

Query: 123 TLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRR 182
            L  ERD L  QT +L+    +L +++ +L++ ++ LRQ+       LE   QE  RLRR
Sbjct: 439 KLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQ-------LEVLEQEAWRLRR 491



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 45/170 (26%), Positives = 75/170 (44%), Gaps = 21/170 (12%)

Query: 73   NLQRDSSTQRLDLEATKARLSSLESLLHQLT---LDQAARPQETQEGLQRELGT----LR 125
            +L+  ++T +  L+A +A    LE  L        DQ  R QE  + LQ+ L      LR
Sbjct: 1993 SLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELR 2052

Query: 126  RERDQLETQTREL-ETAYSNLLRDKSVL-----EEEKKRLRQENENLARRLESSSQEVAR 179
             ++++ +   + L +    N++++K  L     EEE + L Q    L   L    QE+  
Sbjct: 2053 HQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILE 2112

Query: 180  LRRGQCPQTRDTARAVPPGSR----EVSTWNLDTLAFQELKSELTEVPAS 225
            LR     Q R+   A+P   +    E  +  LD+L    L+ EL  + A+
Sbjct: 2113 LRE---TQQRNNLEALPHSHKTSPMEEQSLKLDSLE-PRLQRELERLQAA 2158



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 31/154 (20%), Positives = 66/154 (42%), Gaps = 24/154 (15%)

Query: 66  QAMSVIHNLQRDSSTQRLDLEATKARLSSLESLL-----------------HQLTLDQAA 108
           Q+++ + + +    T+  DL A   +LS+L   L                 +Q    +  
Sbjct: 575 QSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRME 634

Query: 109 RPQETQEGLQRELGTLRRERD-------QLETQTRELETAYSNLLRDKSVLEEEKKRLRQ 161
             ++ +  LQ +L    + R+        LE Q ++ E A + L  D   ++EEK+ +++
Sbjct: 635 AAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQK 694

Query: 162 ENENLARRLESSSQEVARLRRGQCPQTRDTARAV 195
           +      + E+++ ++ +L +    Q    ARAV
Sbjct: 695 KLSESRHQQEAATTQLEQLHQEAKRQEEVLARAV 728



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 11/119 (9%)

Query: 70   VIHNLQRDSSTQR-------LDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELG 122
            +I  L+    TQR       LDLE     L +  S +H L        +E QE  Q    
Sbjct: 1575 LIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQE--- 1631

Query: 123  TLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLR 181
             ++ +R+Q+E   R+ E    +L R    L  +K+R++   +   R+ +   +++ +++
Sbjct: 1632 -VKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIK 1689



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 37/106 (34%), Positives = 50/106 (47%), Gaps = 9/106 (8%)

Query: 83   LDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRR--ERDQLE----TQTR 136
            L L  TKA +SSL+ +   L      R  E Q+ LQ EL   RR  E+++L     T T 
Sbjct: 2178 LSLAQTKASVSSLQEVAMFLQASVLERDSE-QQRLQDELELTRRALEKERLHSPGATSTA 2236

Query: 137  ELETAYSN--LLRDKSVLEEEKKRLRQENENLARRLESSSQEVARL 180
            EL +       L + S +E E      E ++  +RLE   Q VARL
Sbjct: 2237 ELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARL 2282



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 8/113 (7%)

Query: 63  EQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELG 122
           +QS+++S +  L+    +  L+ E  +   + + + L        AR +++   L     
Sbjct: 534 KQSESLSELITLREALESSHLEGELLRQEQTEVTAAL--------ARAEQSIAELSSSEN 585

Query: 123 TLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQ 175
           TL+ E   L     +L      L  DK  L ++  +L +EN+++  R+E++ Q
Sbjct: 586 TLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQ 638



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 36/133 (27%), Positives = 58/133 (43%), Gaps = 11/133 (8%)

Query: 74   LQRDSSTQRL--DLEATKARLSSLESLLHQLTLDQAARPQETQEGLQ-RELGTLRRERDQ 130
            L+RDS  QRL  +LE T+  L   E L        A      ++G+Q  E+  +  E   
Sbjct: 2202 LERDSEQQRLQDELELTRRALEK-ERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSP 2260

Query: 131  LETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRD 190
               + +       +L +  + LE ++ RL++ N  L   LE   +E  +L+       R+
Sbjct: 2261 DGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLK-------RE 2313

Query: 191  TARAVPPGSREVS 203
              RA   GS E+S
Sbjct: 2314 AMRAAQAGSLEIS 2326



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 34/134 (25%), Positives = 62/134 (46%), Gaps = 9/134 (6%)

Query: 58   ESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSL-ESLLHQLTLDQAA----RPQE 112
            ES   E  + M+ + +  R +  QR++ +  +  L +  E+L  Q+   QAA    R Q 
Sbjct: 1312 ESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQA 1371

Query: 113  TQEGLQRELGTLRRERDQLETQTRELET--AYSNLLRDKSVLEEEKKRLRQENENLARRL 170
            +  G+  E   LR  R  L+ +  E+E+    +  L+++  L+  + +  QEN  L  + 
Sbjct: 1372 SAAGILEE--DLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQT 1429

Query: 171  ESSSQEVARLRRGQ 184
             +  +E     RGQ
Sbjct: 1430 LAEREEEVETLRGQ 1443



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 41/168 (24%), Positives = 72/168 (42%), Gaps = 17/168 (10%)

Query: 63   EQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELG 122
            E+SQ  + + +LQR  S  + +    + + +SLES L +L         ET   LQ  L 
Sbjct: 1279 EKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMEL--------HETMASLQSRLR 1330

Query: 123  TLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLES---SSQEVAR 179
                +R + + +   L+ A  NL      L+      R +  + A  LE    +++   +
Sbjct: 1331 RAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQ-ASAAGILEEDLRTARSALK 1389

Query: 180  LRRGQCPQTRDTARAV-PPGSREVSTWNLDTLAFQELKSELTEVPASR 226
            L+  +    R+ A+A+   G  +V+       A QE  + LT+  A R
Sbjct: 1390 LKNEEVESERERAQALQEQGELKVAQGK----ALQENLALLTQTLAER 1433



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 16/113 (14%)

Query: 67   AMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRR 126
            A+ +  N  +    Q+L  E    R +   +L H LTLD   R QE    LQ +      
Sbjct: 1559 ALELEENHHKMECQQKLIKELEGQRETQRVALTH-LTLDLEERSQE----LQAQ------ 1607

Query: 127  ERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVAR 179
                  +Q  +LE+  + L R+    ++E K  R++ E L R+ E  +Q++ R
Sbjct: 1608 -----SSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLER 1655



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 42/154 (27%), Positives = 60/154 (38%), Gaps = 22/154 (14%)

Query: 74  LQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLET 133
           LQ+     R  LE  +     L  +  +L L Q    Q  +E  Q EL    RER++L+ 
Sbjct: 468 LQKAREELRQQLEVLEQEAWRLRRVNVELQL-QGDSAQGQKEEQQEELHLAVRERERLQE 526

Query: 134 QTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTAR 193
               LE   S  L +   L E               LESS  E   LR+ Q   T   AR
Sbjct: 527 MLMGLEAKQSESLSELITLREA--------------LESSHLEGELLRQEQTEVTAALAR 572

Query: 194 AVPPGSREVSTWNLDTLAFQELKSELTEVPASRI 227
           A    +   S+ N        LK+E+ ++ A+ +
Sbjct: 573 AEQSIAELSSSEN-------TLKTEVADLRAAAV 599



 Score = 29.3 bits (64), Expect = 8.8
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 13/117 (11%)

Query: 74   LQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQ------RELGTLRRE 127
            LQ +SS+   D    + ++  L+S L      Q    QE QE L+      R    L RE
Sbjct: 994  LQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELERE 1053

Query: 128  RDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQ-------ENENLARRLESSSQEV 177
            +  L     E E     L    S+ ++E   LRQ       E + L+ ++E   QEV
Sbjct: 1054 KASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEV 1110


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,758,224
Number of Sequences: 37866
Number of extensions: 838329
Number of successful extensions: 6580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 243
Number of HSP's successfully gapped in prelim test: 461
Number of HSP's that attempted gapping in prelim test: 4069
Number of HSP's gapped (non-prelim): 2515
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.