BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|45446752 aquaporin 8 [Homo sapiens] (261 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|45446752 aquaporin 8 [Homo sapiens] 526 e-150 gi|4502183 aquaporin 5 [Homo sapiens] 129 2e-30 gi|4502179 aquaporin 2 [Homo sapiens] 119 2e-27 gi|4755125 aquaporin 4 isoform b [Homo sapiens] 117 8e-27 gi|4502181 aquaporin 4 isoform a [Homo sapiens] 117 8e-27 gi|6912506 major intrinsic protein of lens fiber [Homo sapiens] 112 2e-25 gi|86792455 aquaporin 6 [Homo sapiens] 108 6e-24 gi|37694062 aquaporin 1 [Homo sapiens] 99 4e-21 gi|157266307 aquaporin 9 [Homo sapiens] 81 8e-16 gi|4826645 aquaporin 3 [Homo sapiens] 77 2e-14 gi|4502187 aquaporin 7 [Homo sapiens] 58 7e-09 gi|22538420 aquaporin 10 [Homo sapiens] 53 2e-07 gi|156447037 aquaporin 12B [Homo sapiens] 38 0.010 gi|40538880 aquaporin 12A [Homo sapiens] 37 0.023 gi|27370565 aquaporin 11 [Homo sapiens] 36 0.030 gi|6912666 sialin [Homo sapiens] 34 0.15 gi|83921614 cytochrome b5 outer mitochondrial membrane precursor... 30 2.8 gi|197100650 NTPase, KAP family P-loop domain containing 1 isofo... 29 3.6 gi|115647960 NTPase, KAP family P-loop domain containing 1 isofo... 29 3.6 gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens] 29 3.6 gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 29 4.7 gi|4505697 pendrin [Homo sapiens] 28 6.2 gi|110431350 endo-beta-N-acetylglucosaminidase [Homo sapiens] 28 6.2 gi|73611906 phosphorylase kinase, beta isoform b [Homo sapiens] 28 8.1 gi|4505783 phosphorylase kinase, beta isoform a [Homo sapiens] 28 8.1 >gi|45446752 aquaporin 8 [Homo sapiens] Length = 261 Score = 526 bits (1356), Expect = e-150 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MSGEIAMCEPEFGNDKAREPSVGGRWRVSWYERFVQPCLVELLGSALFIFIGCLSVIENG 60 MSGEIAMCEPEFGNDKAREPSVGGRWRVSWYERFVQPCLVELLGSALFIFIGCLSVIENG Sbjct: 1 MSGEIAMCEPEFGNDKAREPSVGGRWRVSWYERFVQPCLVELLGSALFIFIGCLSVIENG 60 Query: 61 TDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLG 120 TDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLG Sbjct: 61 TDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLG 120 Query: 121 GMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEK 180 GMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEK Sbjct: 121 GMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEK 180 Query: 181 TKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLL 240 TKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLL Sbjct: 181 TKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLL 240 Query: 241 VGLLIRCFIGDGKTRLILKAR 261 VGLLIRCFIGDGKTRLILKAR Sbjct: 241 VGLLIRCFIGDGKTRLILKAR 261 >gi|4502183 aquaporin 5 [Homo sapiens] Length = 265 Score = 129 bits (325), Expect = 2e-30 Identities = 80/215 (37%), Positives = 124/215 (57%), Gaps = 8/215 (3%) Query: 34 FVQPCLVELLGSALFIFIGCLSVIE--NGTDTGLLQPALAHGLALGLVIATLGNISGGHF 91 F++ E L + +F+F G S ++ + T +LQ ALA GLA+G + LG +SGGH Sbjct: 10 FLKAVFAEFLATLIFVFFGLGSALKWPSALPT-ILQIALAFGLAIGTLAQALGPVSGGHI 68 Query: 92 NPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQ 151 NPA++LA ++ ++L+ Y +QL+G + GA + V+P N + A Q Sbjct: 69 NPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQ 128 Query: 152 GQVAGALVAEIILTTLLALAVCMGAINEKTKGPLAP-FSIGFAVTVDILAGGPVSGGCMN 210 GQ A+V E+ILT LAL + + +T +P SIG +VT+ L G +G MN Sbjct: 129 GQ---AMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMN 185 Query: 211 PARAFGPAVVANHWN-FHWIYWLGPLLAGLLVGLL 244 PAR+FGPAVV N ++ HW++W+GP++ +L +L Sbjct: 186 PARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAIL 220 >gi|4502179 aquaporin 2 [Homo sapiens] Length = 271 Score = 119 bits (299), Expect = 2e-27 Identities = 74/214 (34%), Positives = 113/214 (52%), Gaps = 7/214 (3%) Query: 34 FVQPCLVELLGSALFIFIGCLSVIE-NGTDTGLLQPALAHGLALGLVIATLGNISGGHFN 92 F + E L + LF+F G S + +LQ A+A GL +G ++ LG+ISG H N Sbjct: 9 FSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHIN 68 Query: 93 PAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQG 152 PAV++A ++ ++++ Y +QLLG + GAAL ++P + G V Sbjct: 69 PAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPAD----IRGDLAVNALSNS 124 Query: 153 QVAG-ALVAEIILTTLLALAVCMGAINEKTKGPLAP-FSIGFAVTVDILAGGPVSGGCMN 210 AG A+ E+ LT L L + + + P P SIGF+V + L G +G MN Sbjct: 125 TTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMN 184 Query: 211 PARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLL 244 PAR+ PAVV ++ HW++W+GPL+ +L LL Sbjct: 185 PARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLL 218 >gi|4755125 aquaporin 4 isoform b [Homo sapiens] Length = 301 Score = 117 bits (294), Expect = 8e-27 Identities = 74/221 (33%), Positives = 116/221 (52%), Gaps = 13/221 (5%) Query: 30 WYERFVQPCLVELLGSALFIFIGCLSVIE-NGTDTGLLQPALAHGLALGLVIATL----G 84 W + F + E L +F+ + S I GT+ L + L GL IAT+ G Sbjct: 8 WTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFG 67 Query: 85 NISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAA 144 +ISGGH NPAV++A + +++ + Y +Q LG ++GA + V+P + G Sbjct: 68 HISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPP----SVVGGL 123 Query: 145 FVTVQEQGQVAG-ALVAEIILTTLLALAVCMGAINEKTK--GPLAPFSIGFAVTVDILAG 201 VT+ AG L+ E+I+T L + +++T G +A +IGF+V + L Sbjct: 124 GVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIA-LAIGFSVAIGHLFA 182 Query: 202 GPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVG 242 +G MNPAR+FGPAV+ +W HWIYW+GP++ +L G Sbjct: 183 INYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAG 223 >gi|4502181 aquaporin 4 isoform a [Homo sapiens] Length = 323 Score = 117 bits (294), Expect = 8e-27 Identities = 74/221 (33%), Positives = 116/221 (52%), Gaps = 13/221 (5%) Query: 30 WYERFVQPCLVELLGSALFIFIGCLSVIE-NGTDTGLLQPALAHGLALGLVIATL----G 84 W + F + E L +F+ + S I GT+ L + L GL IAT+ G Sbjct: 30 WTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFG 89 Query: 85 NISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAA 144 +ISGGH NPAV++A + +++ + Y +Q LG ++GA + V+P + G Sbjct: 90 HISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPP----SVVGGL 145 Query: 145 FVTVQEQGQVAG-ALVAEIILTTLLALAVCMGAINEKTK--GPLAPFSIGFAVTVDILAG 201 VT+ AG L+ E+I+T L + +++T G +A +IGF+V + L Sbjct: 146 GVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIA-LAIGFSVAIGHLFA 204 Query: 202 GPVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVG 242 +G MNPAR+FGPAV+ +W HWIYW+GP++ +L G Sbjct: 205 INYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAG 245 >gi|6912506 major intrinsic protein of lens fiber [Homo sapiens] Length = 263 Score = 112 bits (281), Expect = 2e-25 Identities = 70/214 (32%), Positives = 112/214 (52%), Gaps = 7/214 (3%) Query: 34 FVQPCLVELLGSALFIFIGCLSVIENGTDT-GLLQPALAHGLALGLVIATLGNISGGHFN 92 F + E + ++F G S + +LQ A+A GLAL ++ ++G+ISG H N Sbjct: 9 FWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAMAFGLALATLVQSVGHISGAHVN 68 Query: 93 PAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQG 152 PAV+ A ++ ++L+ Y +QLLG + GAA+ +V+P N A T+ Sbjct: 69 PAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGN---LALNTLHPAV 125 Query: 153 QVAGALVAEIILTTLLALAVCMGAINEKTKGPL--APFSIGFAVTVDILAGGPVSGGCMN 210 V A EI LT L + +E+ G L ++GF++ + L G +G MN Sbjct: 126 SVGQATTVEIFLTLQFVLCI-FATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMN 184 Query: 211 PARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLL 244 PAR+F PA++ ++ HW+YW+GP++ G L LL Sbjct: 185 PARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLL 218 >gi|86792455 aquaporin 6 [Homo sapiens] Length = 282 Score = 108 bits (269), Expect = 6e-24 Identities = 67/205 (32%), Positives = 103/205 (50%), Gaps = 5/205 (2%) Query: 41 ELLGSALFIFIGCLSVIENGTDT-GLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAA 99 E L + L++F G SV+ T +LQ A+ L + + SG H NPAV+LA Sbjct: 30 EFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAF 89 Query: 100 MLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALV 159 ++ ++L + Y +QL+G +GAAL V P + V+ A+ Sbjct: 90 LVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDI---RETLGINVVRNSVSTGQAVA 146 Query: 160 AEIILTTLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAV 219 E++LT L L V + +T G A IG +V + L G +G MNPAR+FGPA+ Sbjct: 147 VELLLTLQLVLCVFASTDSRQTSGSPATM-IGISVALGHLIGIHFTGCSMNPARSFGPAI 205 Query: 220 VANHWNFHWIYWLGPLLAGLLVGLL 244 + + HW++W+GPL+ LL L+ Sbjct: 206 IIGKFTVHWVFWVGPLMGALLASLI 230 >gi|37694062 aquaporin 1 [Homo sapiens] Length = 269 Score = 99.0 bits (245), Expect = 4e-21 Identities = 70/222 (31%), Positives = 113/222 (50%), Gaps = 16/222 (7%) Query: 34 FVQPCLVELLGSALFIFIGCLSVI----ENGTDTGLLQPALAHGLALGLVIATL----GN 85 F + + E L + LF+FI S + G + +Q + LA GL IATL G+ Sbjct: 10 FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGH 69 Query: 86 ISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAF 145 ISG H NPAV+L +L +++ L Y ++Q +G ++ A+ ++ + Sbjct: 70 ISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDL 129 Query: 146 VTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTK---GPLAPFSIGFAVTVDILAGG 202 GQ G EII T L L +C+ A ++ + G AP +IG +V + L Sbjct: 130 ADGVNSGQGLGI---EIIGT--LQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAI 184 Query: 203 PVSGGCMNPARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLL 244 +G +NPAR+FG AV+ ++++ HWI+W+GP + G L L+ Sbjct: 185 DYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLI 226 >gi|157266307 aquaporin 9 [Homo sapiens] Length = 295 Score = 81.3 bits (199), Expect = 8e-16 Identities = 65/235 (27%), Positives = 101/235 (42%), Gaps = 29/235 (12%) Query: 39 LVELLGSALFIFIGC----LSVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNPA 94 L E LG+ + I +GC +++ G G++ + +A+ + I G +SGGH NPA Sbjct: 27 LSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGGVSGGHINPA 86 Query: 95 VSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERF-----------WNASGA 143 VSLA L G + L Y +Q LG +GAA + + NA+ Sbjct: 87 VSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLLIVGENATAH 146 Query: 144 AFVTVQEQGQVAGALVAEIILTTLLALAVCMGAINEKTKGP---LAPFSIGFAVTVDILA 200 F T A+ ++ T++ L + + + G L P +IG + V + Sbjct: 147 IFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAIGLLIIVIASS 206 Query: 201 GGPVSGGCMNPARAFGPAV--VANHW---------NFHWIYWLGPLLAGLLVGLL 244 G SG MNPAR P + W NF WI +GPL+ ++ GL+ Sbjct: 207 LGLNSGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGAVIGGLI 261 >gi|4826645 aquaporin 3 [Homo sapiens] Length = 292 Score = 77.0 bits (188), Expect = 2e-14 Identities = 75/253 (29%), Positives = 108/253 (42%), Gaps = 39/253 (15%) Query: 33 RFVQPCLVELLGSALFIFIGCLSV----IENGTDTGLLQPALAHGLALGLVIATLGNISG 88 R ++ L E LG+ + + GC SV + GT G L LA G A+ L I G +SG Sbjct: 20 RLLRQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSG 79 Query: 89 GHFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFW---------- 138 H NPAV+ A + + L Y ++Q LG LGA + + + W Sbjct: 80 AHLNPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLY-YDAIWHFADNQLFVS 138 Query: 139 --NASGAAFVTVQE-QGQVAGALVAEIILTTLLALAVCMGAINEKTKGP----LAPFSIG 191 N + F T + + I T +L VC+ AI + P L F++G Sbjct: 139 GPNGTAGIFATYPSGHLDMINGFFDQFIGTA--SLIVCVLAIVDPYNNPVPRGLEAFTVG 196 Query: 192 FAVTVDILAGGPVSGGCMNPARAFGP-----------AVVANHWNFHWIYWLGPLL---A 237 V V + G SG +NPAR FGP AV ++ W+ + PLL A Sbjct: 197 LVVLVIGTSMGFNSGYAVNPARDFGPRLFTALAGWGSAVFTTGQHWWWVPIVSPLLGSIA 256 Query: 238 GLLV-GLLIRCFI 249 G+ V L+I C + Sbjct: 257 GVFVYQLMIGCHL 269 >gi|4502187 aquaporin 7 [Homo sapiens] Length = 342 Score = 58.2 bits (139), Expect = 7e-09 Identities = 68/261 (26%), Positives = 103/261 (39%), Gaps = 40/261 (15%) Query: 33 RFVQPCLVELLGSALFIFIGCLSV---IENGTDTGLLQPALAHGLALGLVIATLGNISGG 89 + V+ L E + + + + G SV + N L L G + + + G ISG Sbjct: 32 KMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGA 91 Query: 90 HFNPAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQ 149 H N AV+ A +G + Y + Q LG L AA ++ + G VT Sbjct: 92 HMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVT-- 149 Query: 150 EQGQVAGA----------------LVAEIILTTLLALAVCMGAINEKTKGPLAP----FS 189 G VA A + E LT +L L C+ AI ++ P P Sbjct: 150 --GPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQL--CLFAITDQENNPALPGTEALV 205 Query: 190 IGFAVTVDILAGGPVSGGCMNPAR-----------AFGPAVVANHWNFHWIYWLGPLLAG 238 IG V + ++ G +G +NP+R +G V +N N+ W+ + PLL Sbjct: 206 IGILVVIIGVSLGMNTGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGA 265 Query: 239 LLVGLLIRCFIGDGKTRLILK 259 L G++ FIG R LK Sbjct: 266 YLGGIIYLVFIGSTIPREPLK 286 >gi|22538420 aquaporin 10 [Homo sapiens] Length = 301 Score = 53.1 bits (126), Expect = 2e-07 Identities = 55/200 (27%), Positives = 82/200 (41%), Gaps = 22/200 (11%) Query: 38 CLVELLGSALFIFIG----CLSVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNP 93 CL E LG + + + +V T LA LA+ + I GN+SG H NP Sbjct: 24 CLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLNP 83 Query: 94 AVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQGQ 153 A SLA ++G L V L Y + QLL A+ A V + N +G +TV + Sbjct: 84 AFSLAMCIVGRLPWVKLPIYILVQLLSAFC-ASGATYVLYHDALQNYTGGN-LTVTGPKE 141 Query: 154 VAGALVA-------------EIILTTLLALAVCMGAINEKTKG---PLAPFSIGFAVTVD 197 A + +L T + + + ++ + KG L P +G + Sbjct: 142 TASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVVVGMLILAL 201 Query: 198 ILAGGPVSGGCMNPARAFGP 217 L+ G G +NPAR GP Sbjct: 202 GLSMGANCGIPLNPARDLGP 221 Score = 31.6 bits (70), Expect = 0.73 Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%) Query: 153 QVAGALVAEIILTTLLALAVCMGAINEKTKGPLAPFSIG--FAVTVDILAGGPVSGGCMN 210 Q + +L L AV + +TKG + AVT+ I GG VSG +N Sbjct: 23 QCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGGNVSGAHLN 82 Query: 211 PARAFGPAVVAN-HWNFHWIYWLGPLLA 237 PA + +V W IY L LL+ Sbjct: 83 PAFSLAMCIVGRLPWVKLPIYILVQLLS 110 >gi|156447037 aquaporin 12B [Homo sapiens] Length = 307 Score = 37.7 bits (86), Expect = 0.010 Identities = 52/207 (25%), Positives = 74/207 (35%), Gaps = 20/207 (9%) Query: 50 FIGCLSVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVM 109 F+ +++E G G P L L L +A + G NP VSL L+ +L Sbjct: 51 FLEMRTLVELGPWAGDFGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEESLPG 110 Query: 110 LLPYWVSQLLGGMLGAALAKAVSP---------EERFWNASGAAFVTVQEQGQVAGALVA 160 L +Q LG L + + + +A T G + A A Sbjct: 111 TLLKLAAQGLGMQAACTLTRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACA 170 Query: 161 EIILTTLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVV 220 TLL L A + GP ++ VTV GP + NPA A Sbjct: 171 FCFHLTLLHLRHSPPAYS----GP----AVALLVTVTAYTAGPFTSAFFNPALAASVTFA 222 Query: 221 ANH---WNFHWIYWLGPLLAGLLVGLL 244 + + +YWLGPL +L LL Sbjct: 223 CSGHTLLEYVQVYWLGPLTGMVLAVLL 249 >gi|40538880 aquaporin 12A [Homo sapiens] Length = 295 Score = 36.6 bits (83), Expect = 0.023 Identities = 51/202 (25%), Positives = 72/202 (35%), Gaps = 20/202 (9%) Query: 55 SVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYW 114 +++E G G P L L L +A + G NP VSL L+ +L L Sbjct: 44 TLVELGPWAGDFGPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEQSLPGTLLKL 103 Query: 115 VSQLLGGMLGAALAKAVSP---------EERFWNASGAAFVTVQEQGQVAGALVAEIILT 165 +Q LG L + + + +A T G + A A Sbjct: 104 AAQGLGMQAACTLMRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHL 163 Query: 166 TLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANH-- 223 TLL L A + GP ++ VTV GP + NPA A + Sbjct: 164 TLLHLRHSPPAYS----GP----AVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHT 215 Query: 224 -WNFHWIYWLGPLLAGLLVGLL 244 + +YWLGPL +L LL Sbjct: 216 LLEYVQVYWLGPLTGMVLAVLL 237 >gi|27370565 aquaporin 11 [Homo sapiens] Length = 271 Score = 36.2 bits (82), Expect = 0.030 Identities = 47/194 (24%), Positives = 74/194 (38%), Gaps = 34/194 (17%) Query: 69 ALAHGLALGLVIATLGNISGGHFNPAVSLAAMLIGGLN----LVMLLPYWVSQLLGGMLG 124 +L HGL L G NP + M++GG++ V LL VS L Sbjct: 86 SLVHGLTL----------VGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSRYCT 135 Query: 125 AALAKAVSPEERFWNASGAAFVTVQEQGQVAGALVAEIILTTLLALAVCMGAIN------ 178 +AL W+ G V E+ + +L ++ AVC + Sbjct: 136 SAL----------WSL-GLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSALLHF 184 Query: 179 EKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAVVANHW---NFHWIYWLGPL 235 ++ + L + +T + AGG ++G NPA A + F +YWL P Sbjct: 185 QEVRTKLRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPS 244 Query: 236 LAGLLVGLLIRCFI 249 L LL+ L+ F+ Sbjct: 245 LGILLMILMFSFFL 258 >gi|6912666 sialin [Homo sapiens] Length = 495 Score = 33.9 bits (76), Expect = 0.15 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 34/132 (25%) Query: 39 LVELLGSALFI----FIGCLSVIENGTDTGLLQPALAHGLALGLVIATLGNISGGHFNPA 94 L+ ++G A+F+ FIGC D L L LG ++ S H + A Sbjct: 369 LIGMIGPAVFLVAAGFIGC--------DYSLAVAFLTISTTLGGFCSS--GFSINHLDIA 418 Query: 95 VSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERF--W----------NASG 142 S A +L+G N +P GM+G +AK+++P+ W N G Sbjct: 419 PSYAGILLGITNTFATIP--------GMVGPVIAKSLTPDNTVGEWQTVFYIAAAINVFG 470 Query: 143 AAFVTVQEQGQV 154 A F T+ +G+V Sbjct: 471 AIFFTLFAKGEV 482 >gi|83921614 cytochrome b5 outer mitochondrial membrane precursor [Homo sapiens] Length = 150 Score = 29.6 bits (65), Expect = 2.8 Identities = 9/27 (33%), Positives = 17/27 (62%) Query: 228 WIYWLGPLLAGLLVGLLIRCFIGDGKT 254 W YW+ P++ +L+G L R + + K+ Sbjct: 123 WAYWILPIIGAVLLGFLYRYYTSESKS 149 >gi|197100650 NTPase, KAP family P-loop domain containing 1 isoform 1 [Homo sapiens] Length = 619 Score = 29.3 bits (64), Expect = 3.6 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 6/52 (11%) Query: 64 GLLQPALAHGLALGLVIATLGNISGGHFNPAVSL------AAMLIGGLNLVM 109 GLL A GL +GL+ +LG + GH +P+ SL AA + G L+M Sbjct: 130 GLLALLAALGLGVGLLYLSLGGHALGHGSPSGSLLKVFGGAATTLSGSGLLM 181 >gi|115647960 NTPase, KAP family P-loop domain containing 1 isoform 2 [Homo sapiens] Length = 610 Score = 29.3 bits (64), Expect = 3.6 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 6/52 (11%) Query: 64 GLLQPALAHGLALGLVIATLGNISGGHFNPAVSL------AAMLIGGLNLVM 109 GLL A GL +GL+ +LG + GH +P+ SL AA + G L+M Sbjct: 121 GLLALLAALGLGVGLLYLSLGGHALGHGSPSGSLLKVFGGAATTLSGSGLLM 172 >gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens] Length = 209 Score = 29.3 bits (64), Expect = 3.6 Identities = 14/32 (43%), Positives = 21/32 (65%), Gaps = 1/32 (3%) Query: 94 AVSLAAMLIGGLNLVMLLPYW-VSQLLGGMLG 124 ++ AA+ G N+ +LLP W V+ LL G+LG Sbjct: 21 SLGTAALFAAGANVALLLPNWDVTYLLRGLLG 52 >gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] Length = 425 Score = 28.9 bits (63), Expect = 4.7 Identities = 25/90 (27%), Positives = 37/90 (41%), Gaps = 12/90 (13%) Query: 3 GEIAMCEPEFGNDKAREPSVGGRWRVSWYERFVQPCLVELLGSALFIFIGCLSVIENGTD 62 G+I + E + + A +GG R PCL+ C ++ NG D Sbjct: 77 GDITLLEVDAIVNAANASLLGGGGVDGCIHRAAGPCLLA----------ECRNL--NGCD 124 Query: 63 TGLLQPALAHGLALGLVIATLGNISGGHFN 92 TG + + L VI T+G I+ GH N Sbjct: 125 TGHAKITCGYDLPAKYVIHTVGPIARGHIN 154 >gi|4505697 pendrin [Homo sapiens] Length = 780 Score = 28.5 bits (62), Expect = 6.2 Identities = 28/116 (24%), Positives = 48/116 (41%), Gaps = 11/116 (9%) Query: 95 VSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAA--------LAKAVSPEERFWNASGAAFV 146 V + ++ GGL + ++ Y L+GG AA L ++ + +N + Sbjct: 196 VGIIQLIFGGLQIGFIVRYLADPLVGGFTTAAAFQVLVSQLKIVLNVSTKNYNGVLSIIY 255 Query: 147 TVQEQGQVAGALVAEIILTTLLALAVCMGA--INEKTKGPLAPFSIGFAVTVDILA 200 T+ E Q G LL + VCM +N++ + + P I V V I+A Sbjct: 256 TLVEIFQNIGDTNLADFTAGLLTIVVCMAVKELNDRFRHKI-PVPIPIEVIVTIIA 310 >gi|110431350 endo-beta-N-acetylglucosaminidase [Homo sapiens] Length = 743 Score = 28.5 bits (62), Expect = 6.2 Identities = 13/44 (29%), Positives = 23/44 (52%) Query: 76 LGLVIATLGNISGGHFNPAVSLAAMLIGGLNLVMLLPYWVSQLL 119 +G+ + GN+ GG F+ SL + G ++ + P WV + L Sbjct: 327 VGVDVFARGNVVGGRFDTDKSLELIRKHGFSVALFAPGWVYECL 370 >gi|73611906 phosphorylase kinase, beta isoform b [Homo sapiens] Length = 1086 Score = 28.1 bits (61), Expect = 8.1 Identities = 14/34 (41%), Positives = 18/34 (52%) Query: 72 HGLALGLVIATLGNISGGHFNPAVSLAAMLIGGL 105 HG L LV+ NI G FNP + + A L G+ Sbjct: 605 HGRPLFLVLIREDNIRGSRFNPILDMLAALKKGI 638 >gi|4505783 phosphorylase kinase, beta isoform a [Homo sapiens] Length = 1093 Score = 28.1 bits (61), Expect = 8.1 Identities = 14/34 (41%), Positives = 18/34 (52%) Query: 72 HGLALGLVIATLGNISGGHFNPAVSLAAMLIGGL 105 HG L LV+ NI G FNP + + A L G+ Sbjct: 612 HGRPLFLVLIREDNIRGSRFNPILDMLAALKKGI 645 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.141 0.447 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,950,036 Number of Sequences: 37866 Number of extensions: 423706 Number of successful extensions: 1207 Number of sequences better than 10.0: 25 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 1152 Number of HSP's gapped (non-prelim): 28 length of query: 261 length of database: 18,247,518 effective HSP length: 100 effective length of query: 161 effective length of database: 14,460,918 effective search space: 2328207798 effective search space used: 2328207798 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.