Guide to the Human Genome
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Name: MIP Sequence: fasta or formatted (263aa) NCBI GI: 6912506
Description:

major intrinsic protein of lens fiber

Referenced in:

Aquaporins
Crystallins and Other Eye Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            12.5         33           2
 C cysteine            0.8          2           1
 D aspartate           1.1          3           1
 E glutamate           3.0          8           1
 F phenylalanine       7.6         20           2
 G glycine            10.3         27           3
 H histidine           2.3          6           1
 I isoleucine          3.0          8           2
 K lysine              1.1          3           1
 L leucine            14.1         37           2
 M methionine          2.3          6           1
 N asparagine          3.4          9           1
 P proline             4.9         13           2
 Q glutamine           3.4          9           1
 R arginine            3.8         10           2
 S serine              6.8         18           2
 T threonine           5.3         14           2
 V valine              9.1         24           1
 W tryptophan          1.9          5           1
 Y tyrosine            3.0          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   major intrinsic protein of lens fiber 
AQP2                  0.602   aquaporin 2 
AQP5                  0.512   aquaporin 5 
AQP6                  0.458   aquaporin 6 
AQP4                  0.424   aquaporin 4 isoform b 
AQP4                  0.424   aquaporin 4 isoform a 
AQP1                  0.416   aquaporin 1 
AQP8                  0.174   aquaporin 8 
AQP7                  0.124   aquaporin 7 
AQP9                  0.112   aquaporin 9 
AQP3                  0.102   aquaporin 3 
AQP10                 0.066   aquaporin 10 
SLC7A1                0.010   solute carrier family 7 (cationic amino acid transpor...
SLC26A3               0.010   solute carrier family 26, member 3 
SLC7A3                0.010   solute carrier family 7 (cationic amino acid transp...
SLC7A3                0.010   solute carrier family 7 (cationic amino acid transp...
AQP12A                0.010   aquaporin 12A 
SLC7A2                0.008   solute carrier family 7, member 2 isoform 1 
SLC7A2                0.008   solute carrier family 7, member 2 isoform 2 
PRAF2                 0.008   PRA1 domain family, member 2 
CUTA                  0.008   cutA divalent cation tolerance homolog isoform 3 [Ho...
SEZ6L2                0.006   seizure related 6 homolog (mouse)-like 2 isoform 4 ...
SEZ6L2                0.006   seizure related 6 homolog (mouse)-like 2 isoform 1 [H...
SEZ6L2                0.006   seizure related 6 homolog (mouse)-like 2 isoform 3 ...
SEZ6L2                0.006   seizure related 6 homolog (mouse)-like 2 isoform 2 ...
DHPS                  0.006   deoxyhypusine synthase isoform c 
AQP12B                0.006   aquaporin 12B 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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