Search of human proteins with 45331217

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45331217 zinc finger protein 526 [Homo sapiens]
         (670 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45331217 zinc finger protein 526 [Homo sapiens]                   1412   0.0  
gi|154744870 zinc finger protein 574 [Homo sapiens]                   420   e-117
gi|55769537 zinc finger protein 658 [Homo sapiens]                    228   2e-59
gi|222831664 zinc finger protein 184 [Homo sapiens]                   225   9e-59
gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor...   224   2e-58
gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor...   224   2e-58
gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor...   224   2e-58
gi|188497655 zinc finger protein 84 [Homo sapiens]                    224   2e-58
gi|188497653 zinc finger protein 84 [Homo sapiens]                    224   2e-58
gi|34419633 zinc finger protein 135 [Homo sapiens]                    222   1e-57
gi|222418585 zinc finger protein 814 [Homo sapiens]                   221   2e-57
gi|52138523 zinc finger protein 418 [Homo sapiens]                    219   8e-57
gi|96303826 zinc finger protein 16 [Homo sapiens]                     216   4e-56
gi|38045954 zinc finger protein 16 [Homo sapiens]                     216   4e-56
gi|188528633 zinc finger protein 79 [Homo sapiens]                    214   3e-55
gi|194328783 zinc finger protein 287 [Homo sapiens]                   213   4e-55
gi|37574603 zinc finger protein 256 [Homo sapiens]                    212   1e-54
gi|20304115 zinc finger protein 551 [Homo sapiens]                    211   1e-54
gi|190570172 zinc finger protein 180 [Homo sapiens]                   210   3e-54
gi|167830431 zinc finger protein 530 [Homo sapiens]                   210   4e-54
gi|148596977 zinc finger protein 31 [Homo sapiens]                    208   1e-53
gi|48717244 zinc finger protein 782 [Homo sapiens]                    207   3e-53
gi|38348236 zinc finger protein 497 [Homo sapiens]                    206   4e-53
gi|33859678 zinc finger protein 416 [Homo sapiens]                    206   4e-53
gi|4507975 zinc finger protein 345 [Homo sapiens]                     206   6e-53
gi|54291710 zinc finger protein 835 [Homo sapiens]                    205   1e-52
gi|4508035 zinc finger protein 7 [Homo sapiens]                       205   1e-52
gi|110349775 zinc finger protein 12 isoform b [Homo sapiens]          204   2e-52
gi|66348108 zinc finger protein 12 isoform a [Homo sapiens]           204   2e-52
gi|149192841 zinc finger protein 527 [Homo sapiens]                   203   4e-52

>gi|45331217 zinc finger protein 526 [Homo sapiens]
          Length = 670

 Score = 1412 bits (3654), Expect = 0.0
 Identities = 670/670 (100%), Positives = 670/670 (100%)

Query: 1   MAEVVAEVAEMPTQMSPGAVEMSTPMSAEMMEMSTEVTEMTPGEALASSLFFQHHQFMCS 60
           MAEVVAEVAEMPTQMSPGAVEMSTPMSAEMMEMSTEVTEMTPGEALASSLFFQHHQFMCS
Sbjct: 1   MAEVVAEVAEMPTQMSPGAVEMSTPMSAEMMEMSTEVTEMTPGEALASSLFFQHHQFMCS 60

Query: 61  ECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLILSP 120
           ECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLILSP
Sbjct: 61  ECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLILSP 120

Query: 121 GELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPP 180
           GELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPP
Sbjct: 121 GELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPP 180

Query: 181 TPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEE 240
           TPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEE
Sbjct: 181 TPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEE 240

Query: 241 DEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPAS 300
           DEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPAS
Sbjct: 241 DEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPAS 300

Query: 301 ATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARY 360
           ATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARY
Sbjct: 301 ATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARY 360

Query: 361 LCVDCGRGFGTELTLVAHRRAHTANPLHRCRCGKTFSNMTKFLYHRRTHAGKSGAPPTGA 420
           LCVDCGRGFGTELTLVAHRRAHTANPLHRCRCGKTFSNMTKFLYHRRTHAGKSGAPPTGA
Sbjct: 361 LCVDCGRGFGTELTLVAHRRAHTANPLHRCRCGKTFSNMTKFLYHRRTHAGKSGAPPTGA 420

Query: 421 TAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKG 480
           TAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKG
Sbjct: 421 TAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKG 480

Query: 481 FKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQS 540
           FKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQS
Sbjct: 481 FKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQS 540

Query: 541 SNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARART 600
           SNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARART
Sbjct: 541 SNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARART 600

Query: 601 LTLQPPRSPSPAPPPPPEPQQTIMCTELGETIAIIETSQPLALEDTLQLCQAALGASEAG 660
           LTLQPPRSPSPAPPPPPEPQQTIMCTELGETIAIIETSQPLALEDTLQLCQAALGASEAG
Sbjct: 601 LTLQPPRSPSPAPPPPPEPQQTIMCTELGETIAIIETSQPLALEDTLQLCQAALGASEAG 660

Query: 661 GLLQLDTAFV 670
           GLLQLDTAFV
Sbjct: 661 GLLQLDTAFV 670


>gi|154744870 zinc finger protein 574 [Homo sapiens]
          Length = 896

 Score =  420 bits (1079), Expect = e-117
 Identities = 267/668 (39%), Positives = 336/668 (50%), Gaps = 131/668 (19%)

Query: 44  EALASSLFFQHHQFMCSECGSLYNTLEEVLSHQEQH-------MLAVSEEEAL----TTQ 92
           E    ++ +  H+++CSEC  LY +LEEVL HQ  H       ++ V++        T  
Sbjct: 3   EESEETVLYIEHRYVCSECNQLYGSLEEVLMHQNSHVPQQHFELVGVADPGVTVATDTAS 62

Query: 93  NVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQ--------------- 137
             GL   LV   E  +QC EC QL++SP +LL HQ+ HL+  A Q               
Sbjct: 63  GTGLYQTLVQ--ESQYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPSPKAPPLS 120

Query: 138 ---IQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPP-------- 186
              I Y+C DC+ LF S ELW+ HR+  HL AT  + P P  L  P  L PP        
Sbjct: 121 SSTIHYECVDCKALFASQELWLNHRQT-HLRATPTKAPAPVVLGSPVVLGPPVGQARVAV 179

Query: 187 --------------SPPS----------EVKMEPYECPECSTLCATPEEFLEHQGTHFDS 222
                         + PS          EV++  Y+C ECS L   P +FLEHQ THF +
Sbjct: 180 EHSYRKAEEGGEGATVPSAAATTTEVVTEVELLLYKCSECSQLFQLPADFLEHQATHFPA 239

Query: 223 -LEKEERNGLEEEEEDDEEDE----EDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGD 277
            + + +   L++E +     E    + D     + +      +A+G D            
Sbjct: 240 PVPESQEPALQQEVQASSPAEVPVSQPDPLPASDHSYELRNGEAIGRDRR---------- 289

Query: 278 CPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTC 337
                   G R +   +  +  +AT    CS C + F S ++LQ H R+H  G  +C  C
Sbjct: 290 --------GRRARRNNSGEAGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLC 341

Query: 338 SKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCRCGKTFS 397
           S+VF   +SL+QHL  H  E+ +LCVDCG  FGTE  L+AHRRAHT NPLH C CGKTF 
Sbjct: 342 SRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCPCGKTFV 401

Query: 398 NMTKFLYHRRTHAGKSGAP-PTGATAP---------PAPA---EPTPPPPP--------P 436
           N+TKFLYHRRTH G  G P PT    P         PAPA   EP  P PP        P
Sbjct: 402 NLTKFLYHRRTH-GVGGVPLPTTPVPPEEPVIGFPEPAPAETGEPEAPEPPVSEETSAGP 460

Query: 437 APPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTG 496
           A P    C  CS+ F  A +L+RH+R VH   ERRH+C +CGK FKK  HVRNHLRTHTG
Sbjct: 461 AAPGTYRCLLCSREFGKALQLTRHQRFVH-RLERRHKCSICGKMFKKKSHVRNHLRTHTG 519

Query: 497 ERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLR---- 552
           ERPF C  C K F S ANL+RH+LTHTG RPY+C DCGK FTQSS L+QHR +H +    
Sbjct: 520 ERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVHAQHFPY 579

Query: 553 -----PVAFARAPRLPI-----TGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARARTLT 602
                 V F R  RL +     TG Y   PY C  C R F     L +HQ V    R   
Sbjct: 580 RCQECGVRFHRPYRLLMHRYHHTGEY---PYKCRECPRSFLLRRLLEVHQLVVHAGR--- 633

Query: 603 LQPPRSPS 610
            QP R PS
Sbjct: 634 -QPHRCPS 640



 Score =  186 bits (473), Expect = 5e-47
 Identities = 163/574 (28%), Positives = 216/574 (37%), Gaps = 116/574 (20%)

Query: 56  QFMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQ 115
           +  CS C  L+ +  ++  H   H                         EG F+C  CS+
Sbjct: 308 ELFCSACDQLFLSPHQLQQHLRSHR------------------------EGVFKCPLCSR 343

Query: 116 LILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQ------------- 162
           +  SP  L    D HL + +++  + C DC   F +  L +AHR+A              
Sbjct: 344 VFPSPSSL----DQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCPCGKT 399

Query: 163 -------------HLSATVAEP--PVPPPLPP---PTPLPP-------PSPP--SEVKME 195
                        H    V  P  PVPP  P    P P P        P PP   E    
Sbjct: 400 FVNLTKFLYHRRTHGVGGVPLPTTPVPPEEPVIGFPEPAPAETGEPEAPEPPVSEETSAG 459

Query: 196 P-----YECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMED 250
           P     Y C  CS       +   HQ      LE+  +  +  +    +    +      
Sbjct: 460 PAAPGTYRCLLCSREFGKALQLTRHQ-RFVHRLERRHKCSICGKMFKKKSHVRNHLRTHT 518

Query: 251 EEAMAEVGDDAVGGDES----------TAGWAQGCGDCPQHQPSAGARRQHRRTAHSPAS 300
            E      D +   +            T      CGDC +    +   RQHR        
Sbjct: 519 GERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLV-----H 573

Query: 301 ATH-PFHCSQCQRSFSSANRLQAHGRAHVGG-THECTTCSKVFKKAASLEQH-LRLHRGE 357
           A H P+ C +C   F    RL  H   H G   ++C  C + F     LE H L +H G 
Sbjct: 574 AQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVVHAGR 633

Query: 358 ARYLCVDCGRGFGTELTLVAHRRAHTANPLHR---C-RCGKTFSNMTKFLYHRRTHAGKS 413
             + C  CG  F + L L  HR A  A    R   C  CGK   +  +   H   HA  +
Sbjct: 634 QPHRCPSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAA-A 692

Query: 414 GAPPTGATAPPAPAEPTPPPPPPAPPAQL-----------------PCPQCSKSFASASR 456
           G     A  PPAP  P     P A PA L                  C +C K F++ + 
Sbjct: 693 GPGEVLAKEPPAPRAPRATRAPVASPAALGSTATASPAAPARRRGLECSECKKLFSTETS 752

Query: 457 LSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLS 516
           L  HRR   G  ER + C  CGK F++  H+++H R HTGERPF C  CGK FA    L+
Sbjct: 753 LQVHRRIHTG--ERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLA 810

Query: 517 RHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLH 550
            H+  HTG RPY C DCGK +   SNL +HR+ H
Sbjct: 811 EHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTH 844



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 123/602 (20%), Positives = 190/602 (31%), Gaps = 160/602 (26%)

Query: 99  ELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRES------------------------ 134
           E V   E  + C EC+QL  S  E+L HQ++H+ +                         
Sbjct: 7   ETVLYIEHRYVCSECNQLYGSLEEVLMHQNSHVPQQHFELVGVADPGVTVATDTASGTGL 66

Query: 135 ----ANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPS 190
                 + QYQC +C +L  SP   + H++  HL     +  VP     P+P  PP   S
Sbjct: 67  YQTLVQESQYQCLECGQLLMSPSQLLEHQEL-HLKMMAPQEAVPAE---PSPKAPPLSSS 122

Query: 191 EVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMED 250
            +    YEC +C  L A+ E +L H+ TH  +   +                        
Sbjct: 123 TIH---YECVDCKALFASQELWLNHRQTHLRATPTKA----------------------- 156

Query: 251 EEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQC 310
             A   +G   V G              P  Q        +R+       AT P   +  
Sbjct: 157 -PAPVVLGSPVVLGP-------------PVGQARVAVEHSYRKAEEGGEGATVPSAAATT 202

Query: 311 QRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLH------RGEARYLCVD 364
               +    L           ++C+ CS++F+  A   +H   H        +   L  +
Sbjct: 203 TEVVTEVELL----------LYKCSECSQLFQLPADFLEHQATHFPAPVPESQEPALQQE 252

Query: 365 CGRGFGTELTLVAHRRAHTANPLHRCRCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPP 424
                  E+ +        ++  +  R G+      +    RR ++G++G   T      
Sbjct: 253 VQASSPAEVPVSQPDPLPASDHSYELRNGEAIGRDRRGRRARRNNSGEAGGAATQELFCS 312

Query: 425 APAEPTPPPPPPAPPAQ------LPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCG 478
           A  +    P       +        CP CS+ F S S L +H        E    C  CG
Sbjct: 313 ACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLG--DHSSESHFLCVDCG 370

Query: 479 KGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTH---------------- 522
             F     +  H R HT   P     CGKTF +L     H+ TH                
Sbjct: 371 LAFGTEALLLAHRRAHT-PNPLHSCPCGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEE 429

Query: 523 --------------------------TGARP-----YQCLDCGKRFTQSSNLQQHRRLHL 551
                                     T A P     Y+CL C + F ++  L +H+R   
Sbjct: 430 PVIGFPEPAPAETGEPEAPEPPVSEETSAGPAAPGTYRCLLCSREFGKALQLTRHQRFVH 489

Query: 552 RPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARARTLTLQPPRSPSP 611
           R                 +  + C  CG+ F+  + +R H R H   R         P  
Sbjct: 490 RL----------------ERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFN 533

Query: 612 AP 613
           +P
Sbjct: 534 SP 535



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 28/123 (22%), Positives = 43/123 (34%), Gaps = 21/123 (17%)

Query: 497 ERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAF 556
           E  + C  C + + SL  +  HQ +H   + ++ +                     P   
Sbjct: 13  EHRYVCSECNQLYGSLEEVLMHQNSHVPQQHFELVGVAD-----------------PGVT 55

Query: 557 ARAPRLPITGLYN----KSPYYCGTCGRWFRAMAGLRLHQRVHARARTLTLQPPRSPSPA 612
                   TGLY     +S Y C  CG+   + + L  HQ +H +        P  PSP 
Sbjct: 56  VATDTASGTGLYQTLVQESQYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPSPK 115

Query: 613 PPP 615
            PP
Sbjct: 116 APP 118



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 48/224 (21%), Positives = 65/224 (29%), Gaps = 36/224 (16%)

Query: 43  GEALASSLFFQHHQ-----------FMCSECGSLYNTLEEVLSHQEQHMLA------VSE 85
           G A  SSL  + H+           F C  CG    +   + +H+  H  A        E
Sbjct: 642 GAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKE 701

Query: 86  EEALTTQNVGLEPELVPGAEGP--------------FQCGECSQLILSPGELLAHQDAHL 131
             A         P   P A G                +C EC +L  +   L  H+  H 
Sbjct: 702 PPAPRAPRATRAPVASPAALGSTATASPAAPARRRGLECSECKKLFSTETSLQVHRRIHT 761

Query: 132 RESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSE 191
            E      Y C DC + F        HR+        A             L        
Sbjct: 762 GERP----YPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRR-IH 816

Query: 192 VKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEE 235
               PY CP+C     +     +H+ TH    +   R  L E E
Sbjct: 817 TGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAE 860



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 12/66 (18%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEV----LSHQEQHMLAVSEEEALT 90
           G+A A S+    H+        + C +CG  Y +   +     +HQ+QH  AV ++ A  
Sbjct: 800 GKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEA 859

Query: 91  TQNVGL 96
              VGL
Sbjct: 860 EAAVGL 865


>gi|55769537 zinc finger protein 658 [Homo sapiens]
          Length = 1059

 Score =  228 bits (580), Expect = 2e-59
 Identities = 166/584 (28%), Positives = 238/584 (40%), Gaps = 89/584 (15%)

Query: 57   FMCSECGSLYNTLEEVLSHQEQHM-----LAVSEEEALTTQNVGLEPELVPGAEGPFQCG 111
            + C ECG  ++    + +HQ  H        V  E+  + +      + V   E P++C 
Sbjct: 518  YECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECN 577

Query: 112  ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAH------------- 158
            +C +       L AHQ  H  E      Y+C DC++ F       AH             
Sbjct: 578  DCGKSFTYNSALRAHQRIHTGEKP----YECSDCEKTFAHNSALRAHHRIHTGEKPYECN 633

Query: 159  ---RKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEH 215
               R   H+S   A   +                     +PYEC EC            H
Sbjct: 634  ECGRSFAHISVLKAHQRI-----------------HTGEKPYECNECGRSFTYNSALRAH 676

Query: 216  QGTHF--------DSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDES 267
            Q  H         D  +    N   +  +     E+  E  E E+  A         +  
Sbjct: 677  QRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIH 736

Query: 268  TAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAH 327
            T      C +C +          HRR      +   P+ CS+C ++FS  + L  H R H
Sbjct: 737  TGEKLYECSECGKTFFQKTRLSTHRRIH----TGEKPYECSKCGKTFSQKSYLSGHERIH 792

Query: 328  VGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANP 386
             G   +EC  C K F   A+L  H R+H GE  Y C  CG+ F     L AH+R HT   
Sbjct: 793  TGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEK 852

Query: 387  LHRCR-CGKTFSNMTKFLYHRRTHAGKS-------GAPPTGATAPPAPAEPTPPPPPPAP 438
             + C  CGKTF++ +    H R H G+        G   +  +   A         P   
Sbjct: 853  PYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKP--- 909

Query: 439  PAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGER 498
                 C +C K+F+  S +S H+R   G  E+ + C VCGK F     +R H R HTGE+
Sbjct: 910  ---YECSECGKTFSEKSYVSAHQRVHTG--EKPYECNVCGKPFAHNSTLRVHQRIHTGEK 964

Query: 499  PFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFAR 558
             ++C+ CGKTF+  ++LS HQ  HTG +PY+C +CGK F Q+S L+ H+R+H        
Sbjct: 965  SYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRIH-------- 1016

Query: 559  APRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQ-RVHARARTL 601
                  TG   + PY C  CG+ F   A LR+H  R+H R +TL
Sbjct: 1017 ------TG---EKPYECDECGKTFVRKAALRVHHTRMHTREKTL 1051



 Score =  211 bits (537), Expect = 2e-54
 Identities = 162/588 (27%), Positives = 236/588 (40%), Gaps = 98/588 (16%)

Query: 62   CGSLYNTLEEVLSHQE---QHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLIL 118
            CG  Y +   ++ HQ+   +  L    E   T+   G +  L+   E P++C EC +   
Sbjct: 473  CGRSYKS--PLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILM--GEKPYECIECGKTFS 528

Query: 119  SPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQ---------------- 162
                L AHQ  H  E      Y+C +C++ F        H++                  
Sbjct: 529  KTSHLRAHQRIHTGEK----PYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFT 584

Query: 163  -------HLSATVAEPPVPPPLPPPTPLPPPSPPSEVKM----EPYECPECSTLCATPEE 211
                   H      E P        T     +  +  ++    +PYEC EC    A    
Sbjct: 585  YNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISV 644

Query: 212  FLEHQGTHFDSLEKE--------ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVG 263
               HQ  H      E          N      +      +  E  + E+  A      + 
Sbjct: 645  LKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIH 704

Query: 264  GDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAH 323
                T      C +C +      A R H+       +    + CS+C ++F    RL  H
Sbjct: 705  QRIHTGEKPYECNECEKTFAHNSALRAHQNI----HTGEKLYECSECGKTFFQKTRLSTH 760

Query: 324  GRAHVG-GTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAH 382
             R H G   +EC+ C K F + + L  H R+H GE  Y C  CG+ F  +  L+ H+R H
Sbjct: 761  RRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIH 820

Query: 383  TANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQ 441
            T    + C +CGKTFS  T    H+R H G+             P E             
Sbjct: 821  TGEKPYECNQCGKTFSQRTHLCAHQRIHTGEK------------PYE------------- 855

Query: 442  LPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQ 501
              C +C K+FA  S L  H R   G  E+ + C  CGK F K  H+R HLRT +GE+P++
Sbjct: 856  --CNECGKTFADNSALRAHHRIHTG--EKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYE 911

Query: 502  CHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVA------ 555
            C  CGKTF+  + +S HQ  HTG +PY+C  CGK F  +S L+ H+R+H    +      
Sbjct: 912  CSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDC 971

Query: 556  ---FARAPRLPI-----TGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
               F++   L       TG   + PY C  CG+ F   + LR+HQR+H
Sbjct: 972  GKTFSQKSHLSAHQRIHTG---EKPYECNECGKAFAQNSTLRVHQRIH 1016



 Score =  186 bits (473), Expect = 5e-47
 Identities = 139/498 (27%), Positives = 194/498 (38%), Gaps = 77/498 (15%)

Query: 111 GECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAE 170
           G+C +       L+ HQ  H  E      YQ  +C + F S    + H            
Sbjct: 387 GKCRKSFYRKAHLIQHQRPHSGEKT----YQYEECAKSFCSSSHPIQH------------ 430

Query: 171 PPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNG 230
                            P + V  + YEC EC           +H   H      +    
Sbjct: 431 -----------------PGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGC 473

Query: 231 LEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQ-GCGDCPQHQPSAG--- 286
               +      ++ D EME        G    G      G  +   G+ P      G   
Sbjct: 474 GRSYKSPLIGHQKTDAEME------LCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTF 527

Query: 287 ARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAA 345
           ++  H R      +   P+ C +C+++FS    L  H R H G   +EC  C K F   +
Sbjct: 528 SKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNS 587

Query: 346 SLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLY 404
           +L  H R+H GE  Y C DC + F     L AH R HT    + C  CG++F++++    
Sbjct: 588 ALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKA 647

Query: 405 HRRTHAGKS-------GAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRL 457
           H+R H G+        G   T  +A  A         P        C  C K+FA  S L
Sbjct: 648 HQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKP------YECSDCEKTFAHNSAL 701

Query: 458 SRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSR 517
             H+R   G  E+ + C  C K F     +R H   HTGE+ ++C  CGKTF     LS 
Sbjct: 702 KIHQRIHTG--EKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLST 759

Query: 518 HQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGT 577
           H+  HTG +PY+C  CGK F+Q S L  H R+H              TG   + PY C  
Sbjct: 760 HRRIHTGEKPYECSKCGKTFSQKSYLSGHERIH--------------TG---EKPYECNV 802

Query: 578 CGRWFRAMAGLRLHQRVH 595
           CG+ F   A L +HQR+H
Sbjct: 803 CGKTFVYKAALIVHQRIH 820



 Score =  154 bits (389), Expect = 3e-37
 Identities = 105/344 (30%), Positives = 150/344 (43%), Gaps = 30/344 (8%)

Query: 270 GW-AQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHV 328
           GW A     C ++   + A   H++T        H    ++C  +        AH R H 
Sbjct: 321 GWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEH----NECTDALYQKLDFTAHQRIHT 376

Query: 329 GG----THECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTA 384
                 + E   C K F + A L QH R H GE  Y   +C + F +    + H   +  
Sbjct: 377 EDKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVG 436

Query: 385 NPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLP 443
             L+ C  CGK F   +    H R H  +      G       +  +P        A++ 
Sbjct: 437 FKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGC----GRSYKSPLIGHQKTDAEME 492

Query: 444 CPQCSKS-FASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQC 502
              C  S +   S L  H+R + G  E+ + C  CGK F K  H+R H R HTGE+P++C
Sbjct: 493 L--CGGSEYGKTSHLKGHQRILMG--EKPYECIECGKTFSKTSHLRAHQRIHTGEKPYEC 548

Query: 503 HSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHL----------- 551
             C KTF+   +LS HQ  HTG +PY+C DCGK FT +S L+ H+R+H            
Sbjct: 549 VECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCE 608

Query: 552 RPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
           +  A   A R        + PY C  CGR F  ++ L+ HQR+H
Sbjct: 609 KTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIH 652



 Score =  137 bits (346), Expect = 2e-32
 Identities = 117/464 (25%), Positives = 175/464 (37%), Gaps = 74/464 (15%)

Query: 57   FMCSECGSLYNTLEEVLSHQEQHM----LAVSEEEALTTQNVGLE-PELVPGAEGPFQCG 111
            + C+ECG  +     + +HQ  H        S+ E     N  L+  + +   E P++C 
Sbjct: 658  YECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYECN 717

Query: 112  ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
            EC +       L AHQ+ H  E      Y+C +C + F        HR+         E 
Sbjct: 718  ECEKTFAHNSALRAHQNIHTGEKL----YECSECGKTFFQKTRLSTHRRIH-----TGEK 768

Query: 172  PVPPPLPPPTPLPPPSPPSEVKM----EPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
            P        T           ++    +PYEC  C          + HQ  H        
Sbjct: 769  PYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIH-------- 820

Query: 228  RNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGA 287
                          E+  E  +  +  ++           T      C +C +      A
Sbjct: 821  ------------TGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSA 868

Query: 288  RRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAAS 346
             R H R      +   P+ C+ C ++FS  + L+AH R   G   +EC+ C K F + + 
Sbjct: 869  LRAHHRIH----TGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSY 924

Query: 347  LEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYH 405
            +  H R+H GE  Y C  CG+ F    TL  H+R HT    + C  CGKTFS  +    H
Sbjct: 925  VSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAH 984

Query: 406  RRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVH 465
            +R H G+             P E               C +C K+FA  S L  H+R   
Sbjct: 985  QRIHTGEK------------PYE---------------CNECGKAFAQNSTLRVHQRIHT 1017

Query: 466  GPPERRHRCGVCGKGFKKLIHVR-NHLRTHTGERPFQCHSCGKT 508
            G  E+ + C  CGK F +   +R +H R HT E+   C+  GK+
Sbjct: 1018 G--EKPYECDECGKTFVRKAALRVHHTRMHTREKTLACNGFGKS 1059



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 40/157 (25%), Positives = 66/157 (42%), Gaps = 22/157 (14%)

Query: 446 QCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPF---QC 502
           +C ++F+ +S    H++   G     H    C     + +    H R HT ++ +   + 
Sbjct: 329 KCEENFSQSSAHIVHQKTQAGDKFGEHN--ECTDALYQKLDFTAHQRIHTEDKFYLSDEH 386

Query: 503 HSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRL 562
             C K+F   A+L +HQ  H+G + YQ  +C K F  SS+  QH   +   V F      
Sbjct: 387 GKCRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTY---VGFKL---- 439

Query: 563 PITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
                     Y C  CG+ F   + L  H R+H + +
Sbjct: 440 ----------YECNECGKAFCQNSNLSKHLRIHTKEK 466



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 29/129 (22%), Positives = 47/129 (36%), Gaps = 14/129 (10%)

Query: 472 HRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCL 531
           + C   G  F +   +    RT TG   F+ + C + F+  +    HQ T  G +  +  
Sbjct: 297 YECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEHN 356

Query: 532 DCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLH 591
           +C     Q  +   H+R+H     +                   G C + F   A L  H
Sbjct: 357 ECTDALYQKLDFTAHQRIHTEDKFYLSDEH--------------GKCRKSFYRKAHLIQH 402

Query: 592 QRVHARART 600
           QR H+  +T
Sbjct: 403 QRPHSGEKT 411


>gi|222831664 zinc finger protein 184 [Homo sapiens]
          Length = 751

 Score =  225 bits (574), Expect = 9e-59
 Identities = 147/550 (26%), Positives = 228/550 (41%), Gaps = 118/550 (21%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVG---------LEPELVPGAEGP 107
           + C ECG  ++    ++ HQ  H    + E+  T    G         +E + +   E P
Sbjct: 306 YKCDECGKAFSQRTHLVQHQRIH----TGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKP 361

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           F+C EC +       L  HQ  H  E      Y+C +C + F  P  ++ H    H+  T
Sbjct: 362 FKCDECDKTFTRSTHLTQHQKIHTGEKT----YKCNECGKAFNGPSTFIRH----HMIHT 413

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
             +P                         YEC EC    +      +HQ TH        
Sbjct: 414 GEKP-------------------------YECNECGKAFSQHSNLTQHQKTH-------- 440

Query: 228 RNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGA 287
                         E+  +  E  ++ +     A      T      C +C +      +
Sbjct: 441 ------------TGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSS 488

Query: 288 RRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGG-THECTTCSKVFKKAAS 346
             QHRR      +   PF CS+C ++FS  + L  H + H     +EC  C K F +++S
Sbjct: 489 LTQHRRIH----TREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSS 544

Query: 347 LEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYH 405
           L +H R+H GE  Y C +CG+ F    +L+ HR+ HT    ++C  CG+ F+       H
Sbjct: 545 LAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQH 604

Query: 406 RRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVH 465
           +R H G                         A P +  C +C K+F   S L++H++   
Sbjct: 605 KRIHTG-------------------------AKPYE--CAECGKAFRHCSSLAQHQKT-- 635

Query: 466 GPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGA 525
              E+ ++C  C K F +  H+  H R HTGE+P++C+ C K F+   +L+ HQ THTG 
Sbjct: 636 HTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGE 695

Query: 526 RPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAM 585
           +PY C +C K F+QS+ L QH+R+H                   + P+ C  CG+ FR  
Sbjct: 696 KPYNCNECRKTFSQSTYLIQHQRIHS-----------------GEKPFGCNDCGKSFRYR 738

Query: 586 AGLRLHQRVH 595
           + L  HQR+H
Sbjct: 739 SALNKHQRLH 748



 Score =  218 bits (554), Expect = 2e-56
 Identities = 156/567 (27%), Positives = 241/567 (42%), Gaps = 98/567 (17%)

Query: 59  CSECGSLYNTLEEVLSHQEQHM----LAVSE-EEALTTQNVGLEPELVPGAEGPFQCGEC 113
           C+ECG  ++    ++ HQ  H        +E E+A +     +  + +   + P++C +C
Sbjct: 224 CNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQC 283

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
            +  +    L  HQ  H  E      Y+C +C + F      V H++             
Sbjct: 284 GKGFIEGPSLTQHQRIHTGEKP----YKCDECGKAFSQRTHLVQHQRIH----------- 328

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEE 233
                                +PY C EC    +    F+EHQ  H              
Sbjct: 329 ------------------TGEKPYTCNECGKAFSQRGHFMEHQKIHTG------------ 358

Query: 234 EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQ--HQPSAGARRQH 291
             E   + +E D+       + +     +   E T      C +C +  + PS   R   
Sbjct: 359 --EKPFKCDECDKTFTRSTHLTQ--HQKIHTGEKT----YKCNECGKAFNGPSTFIRH-- 408

Query: 292 RRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQH 350
               H   +   P+ C++C ++FS  + L  H + H G   ++C  C K F   +SL QH
Sbjct: 409 ----HMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCAECGKSFSYWSSLAQH 464

Query: 351 LRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTH 409
           L++H GE  Y C +CG+ F    +L  HRR HT      C  CGK FS ++    H++TH
Sbjct: 465 LKIHTGEKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTH 524

Query: 410 AG------KSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
                   K        ++  A  E       P       C +C K+F+  S L +HR+ 
Sbjct: 525 TQEKAYECKECGKAFIRSSSLAKHERIHTGEKP-----YQCHECGKTFSYGSSLIQHRKI 579

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  ER ++C  CG+ F + IH+  H R HTG +P++C  CGK F   ++L++HQ THT
Sbjct: 580 HTG--ERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHT 637

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLHL--RPV-------AFARAPRL-----PITGLYN 569
             +PYQC  C K F+QSS+L QH+R+H   +P        AF+R+  L       TG   
Sbjct: 638 EEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTG--- 694

Query: 570 KSPYYCGTCGRWFRAMAGLRLHQRVHA 596
           + PY C  C + F     L  HQR+H+
Sbjct: 695 EKPYNCNECRKTFSQSTYLIQHQRIHS 721



 Score =  192 bits (488), Expect = 8e-49
 Identities = 125/457 (27%), Positives = 191/457 (41%), Gaps = 57/457 (12%)

Query: 165 SATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTH----- 219
           S  V + P P        +   S P + K +  +C EC    +     + HQ TH     
Sbjct: 191 SNLVTQEPSPEETSTKRSIKQNSNPVK-KEKSCKCNECGKAFSYCSALIRHQRTHTGEKP 249

Query: 220 FDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCP 279
           +   E E+     E   + +     D+  + ++     G   + G   T       G+ P
Sbjct: 250 YKCNECEKAFSRSENLINHQRIHTGDKPYKCDQC----GKGFIEGPSLTQHQRIHTGEKP 305

Query: 280 QHQPSAG---ARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECT 335
                 G   ++R H        +   P+ C++C ++FS       H + H G    +C 
Sbjct: 306 YKCDECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCD 365

Query: 336 TCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGK 394
            C K F ++  L QH ++H GE  Y C +CG+ F    T + H   HT    + C  CGK
Sbjct: 366 ECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGK 425

Query: 395 TFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASA 454
            FS  +    H++TH G+                               C +C KSF+  
Sbjct: 426 AFSQHSNLTQHQKTHTGEK---------------------------PYDCAECGKSFSYW 458

Query: 455 SRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLAN 514
           S L++H +   G  E+ ++C  CGK F     +  H R HT E+PF+C  CGK F+ L+N
Sbjct: 459 SSLAQHLKIHTG--EKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSN 516

Query: 515 LSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKS--- 571
           L++HQ THT  + Y+C +CGK F +SS+L +H R+H     + +      T  Y  S   
Sbjct: 517 LNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTGEKPY-QCHECGKTFSYGSSLIQ 575

Query: 572 ---------PYYCGTCGRWFRAMAGLRLHQRVHARAR 599
                    PY C  CGR F     L  H+R+H  A+
Sbjct: 576 HRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAK 612



 Score =  157 bits (398), Expect = 2e-38
 Identities = 116/497 (23%), Positives = 190/497 (38%), Gaps = 101/497 (20%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EAL 89
           G+A +    F  HQ        F C EC   +     +  HQ+ H    + +     +A 
Sbjct: 340 GKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAF 399

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
              +  +   ++   E P++C EC +       L  HQ  H  E         +DC E  
Sbjct: 400 NGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKP-------YDCAECG 452

Query: 150 PSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATP 209
            S   W +   AQHL     E                        +PY+C EC    +  
Sbjct: 453 KSFSYWSS--LAQHLKIHTGE------------------------KPYKCNECGKAFSYC 486

Query: 210 EEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTA 269
               +H+  H                      E+  E  E  +A + + +        T 
Sbjct: 487 SSLTQHRRIH--------------------TREKPFECSECGKAFSYLSNLNQHQKTHTQ 526

Query: 270 GWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG 329
             A  C +C +    + +  +H R      +   P+ C +C ++FS  + L  H + H G
Sbjct: 527 EKAYECKECGKAFIRSSSLAKHERI----HTGEKPYQCHECGKTFSYGSSLIQHRKIHTG 582

Query: 330 -GTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLH 388
              ++C  C + F +   L QH R+H G   Y C +CG+ F    +L  H++ HT    +
Sbjct: 583 ERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHTEEKPY 642

Query: 389 RC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQC 447
           +C +C KTFS  +    H+R H G+                               C +C
Sbjct: 643 QCNKCEKTFSQSSHLTQHQRIHTGEK---------------------------PYKCNEC 675

Query: 448 SKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGK 507
            K+F+ ++ L+ H+    G  E+ + C  C K F +  ++  H R H+GE+PF C+ CGK
Sbjct: 676 DKAFSRSTHLTEHQNTHTG--EKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGK 733

Query: 508 TFASLANLSRHQLTHTG 524
           +F   + L++HQ  H G
Sbjct: 734 SFRYRSALNKHQRLHPG 750



 Score =  122 bits (305), Expect = 1e-27
 Identities = 63/209 (30%), Positives = 98/209 (46%), Gaps = 46/209 (22%)

Query: 392 CGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSF 451
           CGK FS  +  + H+RTH G+                               C +C K+F
Sbjct: 227 CGKAFSYCSALIRHQRTHTGEK---------------------------PYKCNECEKAF 259

Query: 452 ASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFAS 511
           + +  L  H+R   G  ++ ++C  CGKGF +   +  H R HTGE+P++C  CGK F+ 
Sbjct: 260 SRSENLINHQRIHTG--DKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQ 317

Query: 512 LANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKS 571
             +L +HQ  HTG +PY C +CGK F+Q  +  +H+++H              TG   + 
Sbjct: 318 RTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIH--------------TG---EK 360

Query: 572 PYYCGTCGRWFRAMAGLRLHQRVHARART 600
           P+ C  C + F     L  HQ++H   +T
Sbjct: 361 PFKCDECDKTFTRSTHLTQHQKIHTGEKT 389



 Score =  103 bits (258), Expect = 4e-22
 Identities = 51/134 (38%), Positives = 69/134 (51%), Gaps = 17/134 (12%)

Query: 469 ERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPY 528
           E+  +C  CGK F     +  H RTHTGE+P++C+ C K F+   NL  HQ  HTG +PY
Sbjct: 219 EKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTGDKPY 278

Query: 529 QCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGL 588
           +C  CGK F +  +L QH+R+H              TG   + PY C  CG+ F     L
Sbjct: 279 KCDQCGKGFIEGPSLTQHQRIH--------------TG---EKPYKCDECGKAFSQRTHL 321

Query: 589 RLHQRVHARARTLT 602
             HQR+H   +  T
Sbjct: 322 VQHQRIHTGEKPYT 335


>gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2
           [Homo sapiens]
          Length = 738

 Score =  224 bits (571), Expect = 2e-58
 Identities = 155/565 (27%), Positives = 228/565 (40%), Gaps = 97/565 (17%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELV 101
           S F  HH+       + CS+CG  ++   ++ SHQ  H                      
Sbjct: 248 SQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT--------------------- 286

Query: 102 PGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKA 161
              E P++CGEC +       L++H   H  E      Y C +C   F      + H++ 
Sbjct: 287 --GEKPYECGECGKAFSRKSHLISHWRTHTGEKP----YGCNECGRAFSEKSNLINHQRI 340

Query: 162 QHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFD 221
                                            +P+EC EC    +   + + H  TH  
Sbjct: 341 H-----------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTG 371

Query: 222 SLE---KEERNGLEEEEE-----DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQ 273
           +      + R    E+ E          E+  E  E  +A  E           T     
Sbjct: 372 TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPH 431

Query: 274 GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-H 332
           GC  C +    A +++ H  +     +   PF CS+C ++FS  ++L  H R H G   +
Sbjct: 432 GCIQCGK----AFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 333 ECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-R 391
           EC+ C K F +  SL  H R+H GE  Y+C +CG+ F  +  L++H+R HT    + C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 392 CGKTFSNMTKFLYHRRTHAGKSGAPPTGAT-APPAPAEPTPPPPPPAPPAQLPCPQCSKS 450
           CGK F   +    H+RTH G+          A    ++               C  C K+
Sbjct: 548 CGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKA 607

Query: 451 FASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFA 510
           F   S L RH R   G  E+ + C  C K F++   + NH R HTGE+PF+C  CGK F+
Sbjct: 608 FFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFS 665

Query: 511 SLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNK 570
             ++L  HQ THTG +PY C +C K F+Q S L  H+R+H              TG   +
Sbjct: 666 RKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIH--------------TG---E 708

Query: 571 SPYYCGTCGRWFRAMAGLRLHQRVH 595
            PY C  CG+ F   + L  HQR H
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTH 733



 Score =  222 bits (566), Expect = 8e-58
 Identities = 140/503 (27%), Positives = 220/503 (43%), Gaps = 75/503 (14%)

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           ++C EC +       L+ HQ  H+R+    I + C +C + FP    ++ H +       
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRD----IAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
                        + L      +    +PYEC EC    +     + H  TH      E+
Sbjct: 263 YNCSQCGKAFSQKSQL-TSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEK 317

Query: 228 RNGLEE--EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             G  E      ++ +  + + +   E   E                  C +C +    A
Sbjct: 318 PYGCNECGRAFSEKSNLINHQRIHTGEKPFE------------------CRECGK----A 355

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKA 344
            +R+    T H   + T PF CS C+++F   + L  H   H G   +EC+ C K F++ 
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
           +SL  H R H GE  + C+ CG+ F  +  L++H+  HT      C +CGK FS  ++ +
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+RTH G+             P E               C +C K+F+    L+ H+R 
Sbjct: 476 RHQRTHTGEK------------PYE---------------CSECGKAFSEKLSLTNHQRI 508

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  CGK F +  H+ +H RTHTGE+P++C  CGK F   ++L+ HQ THT
Sbjct: 509 HTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHT 566

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLH----------LRPVAFARAPRLPITGLY-NKSP 572
           G +PY+C DC K F+Q S L  H+R+H           R   F ++  +     +  + P
Sbjct: 567 GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 573 YYCGTCGRWFRAMAGLRLHQRVH 595
           Y C  C + FR  + L  HQR+H
Sbjct: 627 YECNECRKAFREKSSLINHQRIH 649



 Score =  160 bits (406), Expect = 3e-39
 Identities = 91/292 (31%), Positives = 134/292 (45%), Gaps = 47/292 (16%)

Query: 305 FHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVD 364
           + C + + S+  +  +  H        +EC+ C K F K  SL +H   H  +  + C +
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239

Query: 365 CGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAP 423
           CG+ F  +   + H R HT    + C +CGK FS  ++   H+RTH G+           
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---------- 289

Query: 424 PAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKK 483
             P E               C +C K+F+  S L  H R   G  E+ + C  CG+ F +
Sbjct: 290 --PYE---------------CGECGKAFSRKSHLISHWRTHTG--EKPYGCNECGRAFSE 330

Query: 484 LIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNL 543
             ++ NH R HTGE+PF+C  CGK F+  + L  H  THTG +P+ C DC K F + S L
Sbjct: 331 KSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSEL 390

Query: 544 QQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            +H+ +H              TG   + PY C  C + FR  + L  HQR H
Sbjct: 391 IRHQTIH--------------TG---EKPYECSECRKAFRERSSLINHQRTH 425



 Score =  159 bits (402), Expect = 8e-39
 Identities = 115/480 (23%), Positives = 183/480 (38%), Gaps = 81/480 (16%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCGEC 113
           C+ECG  ++    +++HQ  H      E     +A + ++  +          PF C +C
Sbjct: 321 CNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDC 380

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
            +      EL+ HQ  H  E      Y+C +C++ F      + H++             
Sbjct: 381 RKAFFEKSELIRHQTIHTGEKP----YECSECRKAFRERSSLINHQR------------- 423

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSL--------EK 225
                           +    +P+ C +C    +     + HQ TH            + 
Sbjct: 424 ----------------THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKA 467

Query: 226 EERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             R       +     E+  E  E  +A +E           T      C +C +    A
Sbjct: 468 FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK----A 523

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKA 344
             ++ H  +     +   P+ CS+C ++F   + L  H R H G   +EC  C K F + 
Sbjct: 524 FCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK 583

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFL 403
           + L  H R+H GE  Y C  C + F  +  L+ H R HT    + C  C K F   +  +
Sbjct: 584 SQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+R H G+             P E               C +C K+F+  S L  H+R 
Sbjct: 644 NHQRIHTGEK------------PFE---------------CSECGKAFSRKSHLIPHQRT 676

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  C K F +   + NH R HTGE+P++C  CGK F+  + L  HQ THT
Sbjct: 677 HTG--EKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHT 734



 Score =  117 bits (292), Expect = 4e-26
 Identities = 89/372 (23%), Positives = 145/372 (38%), Gaps = 54/372 (14%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHML-----AVSEEEALTTQNVGLEPELVPGAEGPFQCG 111
           + CSEC   +     +++HQ  H        +   +A + ++  +  ++    E PF C 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           +C +      +L+ HQ  H  E      Y+C +C + F S +L + + +  H        
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKP----YECSECGKAF-SEKLSLTNHQRIHTGE----- 512

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKE----- 226
                                  +PY C EC          + HQ TH      E     
Sbjct: 513 -----------------------KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 227 ----ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQ 282
               E++ L   +      E+  E  + E+A ++           T      C  C +  
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 283 PSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVF 341
                  +H RT     +   P+ C++C+++F   + L  H R H G    EC+ C K F
Sbjct: 609 FEKSELIRHLRTH----TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF 664

Query: 342 KKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMT 400
            + + L  H R H GE  Y C +C + F  +  LV H+R HT    +RC  CGK FS  +
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 401 KFLYHRRTHAGK 412
           + + H+RTH  K
Sbjct: 725 QLINHQRTHTVK 736



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 69/321 (21%), Positives = 104/321 (32%), Gaps = 89/321 (27%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A +  L   +HQ        ++CSECG  +     ++SHQ  H               
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHT-------------- 538

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++C EC +       L  HQ  H  E      Y+C DC++ F     
Sbjct: 539 ---------GEKPYECSECGKAFGEKSSLATHQRTHTGEK----PYECRDCEKAFSQKSQ 585

Query: 155 WVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLE 214
              H++                                  +PYEC  C        E + 
Sbjct: 586 LNTHQRI-----------------------------HTGEKPYECSLCRKAFFEKSELIR 616

Query: 215 HQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG 274
           H  TH                      E+  E  E  +A  E           T      
Sbjct: 617 HLRTH--------------------TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFE 656

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHE 333
           C +C +    A +R+ H        +   P+ CS+C+++FS  ++L  H R H G   + 
Sbjct: 657 CSECGK----AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYR 712

Query: 334 CTTCSKVFKKAASLEQHLRLH 354
           C  C K F + + L  H R H
Sbjct: 713 CIECGKAFSQKSQLINHQRTH 733


>gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1
           [Homo sapiens]
          Length = 738

 Score =  224 bits (571), Expect = 2e-58
 Identities = 155/565 (27%), Positives = 228/565 (40%), Gaps = 97/565 (17%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELV 101
           S F  HH+       + CS+CG  ++   ++ SHQ  H                      
Sbjct: 248 SQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT--------------------- 286

Query: 102 PGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKA 161
              E P++CGEC +       L++H   H  E      Y C +C   F      + H++ 
Sbjct: 287 --GEKPYECGECGKAFSRKSHLISHWRTHTGEKP----YGCNECGRAFSEKSNLINHQRI 340

Query: 162 QHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFD 221
                                            +P+EC EC    +   + + H  TH  
Sbjct: 341 H-----------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTG 371

Query: 222 SLE---KEERNGLEEEEE-----DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQ 273
           +      + R    E+ E          E+  E  E  +A  E           T     
Sbjct: 372 TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPH 431

Query: 274 GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-H 332
           GC  C +    A +++ H  +     +   PF CS+C ++FS  ++L  H R H G   +
Sbjct: 432 GCIQCGK----AFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 333 ECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-R 391
           EC+ C K F +  SL  H R+H GE  Y+C +CG+ F  +  L++H+R HT    + C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 392 CGKTFSNMTKFLYHRRTHAGKSGAPPTGAT-APPAPAEPTPPPPPPAPPAQLPCPQCSKS 450
           CGK F   +    H+RTH G+          A    ++               C  C K+
Sbjct: 548 CGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKA 607

Query: 451 FASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFA 510
           F   S L RH R   G  E+ + C  C K F++   + NH R HTGE+PF+C  CGK F+
Sbjct: 608 FFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFS 665

Query: 511 SLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNK 570
             ++L  HQ THTG +PY C +C K F+Q S L  H+R+H              TG   +
Sbjct: 666 RKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIH--------------TG---E 708

Query: 571 SPYYCGTCGRWFRAMAGLRLHQRVH 595
            PY C  CG+ F   + L  HQR H
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTH 733



 Score =  222 bits (566), Expect = 8e-58
 Identities = 140/503 (27%), Positives = 220/503 (43%), Gaps = 75/503 (14%)

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           ++C EC +       L+ HQ  H+R+    I + C +C + FP    ++ H +       
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRD----IAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
                        + L      +    +PYEC EC    +     + H  TH      E+
Sbjct: 263 YNCSQCGKAFSQKSQL-TSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEK 317

Query: 228 RNGLEE--EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             G  E      ++ +  + + +   E   E                  C +C +    A
Sbjct: 318 PYGCNECGRAFSEKSNLINHQRIHTGEKPFE------------------CRECGK----A 355

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKA 344
            +R+    T H   + T PF CS C+++F   + L  H   H G   +EC+ C K F++ 
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
           +SL  H R H GE  + C+ CG+ F  +  L++H+  HT      C +CGK FS  ++ +
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+RTH G+             P E               C +C K+F+    L+ H+R 
Sbjct: 476 RHQRTHTGEK------------PYE---------------CSECGKAFSEKLSLTNHQRI 508

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  CGK F +  H+ +H RTHTGE+P++C  CGK F   ++L+ HQ THT
Sbjct: 509 HTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHT 566

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLH----------LRPVAFARAPRLPITGLY-NKSP 572
           G +PY+C DC K F+Q S L  H+R+H           R   F ++  +     +  + P
Sbjct: 567 GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 573 YYCGTCGRWFRAMAGLRLHQRVH 595
           Y C  C + FR  + L  HQR+H
Sbjct: 627 YECNECRKAFREKSSLINHQRIH 649



 Score =  160 bits (406), Expect = 3e-39
 Identities = 91/292 (31%), Positives = 134/292 (45%), Gaps = 47/292 (16%)

Query: 305 FHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVD 364
           + C + + S+  +  +  H        +EC+ C K F K  SL +H   H  +  + C +
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239

Query: 365 CGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAP 423
           CG+ F  +   + H R HT    + C +CGK FS  ++   H+RTH G+           
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---------- 289

Query: 424 PAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKK 483
             P E               C +C K+F+  S L  H R   G  E+ + C  CG+ F +
Sbjct: 290 --PYE---------------CGECGKAFSRKSHLISHWRTHTG--EKPYGCNECGRAFSE 330

Query: 484 LIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNL 543
             ++ NH R HTGE+PF+C  CGK F+  + L  H  THTG +P+ C DC K F + S L
Sbjct: 331 KSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSEL 390

Query: 544 QQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            +H+ +H              TG   + PY C  C + FR  + L  HQR H
Sbjct: 391 IRHQTIH--------------TG---EKPYECSECRKAFRERSSLINHQRTH 425



 Score =  159 bits (402), Expect = 8e-39
 Identities = 115/480 (23%), Positives = 183/480 (38%), Gaps = 81/480 (16%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCGEC 113
           C+ECG  ++    +++HQ  H      E     +A + ++  +          PF C +C
Sbjct: 321 CNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDC 380

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
            +      EL+ HQ  H  E      Y+C +C++ F      + H++             
Sbjct: 381 RKAFFEKSELIRHQTIHTGEKP----YECSECRKAFRERSSLINHQR------------- 423

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSL--------EK 225
                           +    +P+ C +C    +     + HQ TH            + 
Sbjct: 424 ----------------THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKA 467

Query: 226 EERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             R       +     E+  E  E  +A +E           T      C +C +    A
Sbjct: 468 FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK----A 523

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKA 344
             ++ H  +     +   P+ CS+C ++F   + L  H R H G   +EC  C K F + 
Sbjct: 524 FCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK 583

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFL 403
           + L  H R+H GE  Y C  C + F  +  L+ H R HT    + C  C K F   +  +
Sbjct: 584 SQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+R H G+             P E               C +C K+F+  S L  H+R 
Sbjct: 644 NHQRIHTGEK------------PFE---------------CSECGKAFSRKSHLIPHQRT 676

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  C K F +   + NH R HTGE+P++C  CGK F+  + L  HQ THT
Sbjct: 677 HTG--EKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHT 734



 Score =  117 bits (292), Expect = 4e-26
 Identities = 89/372 (23%), Positives = 145/372 (38%), Gaps = 54/372 (14%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHML-----AVSEEEALTTQNVGLEPELVPGAEGPFQCG 111
           + CSEC   +     +++HQ  H        +   +A + ++  +  ++    E PF C 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           +C +      +L+ HQ  H  E      Y+C +C + F S +L + + +  H        
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKP----YECSECGKAF-SEKLSLTNHQRIHTGE----- 512

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKE----- 226
                                  +PY C EC          + HQ TH      E     
Sbjct: 513 -----------------------KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 227 ----ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQ 282
               E++ L   +      E+  E  + E+A ++           T      C  C +  
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 283 PSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVF 341
                  +H RT     +   P+ C++C+++F   + L  H R H G    EC+ C K F
Sbjct: 609 FEKSELIRHLRTH----TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF 664

Query: 342 KKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMT 400
            + + L  H R H GE  Y C +C + F  +  LV H+R HT    +RC  CGK FS  +
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 401 KFLYHRRTHAGK 412
           + + H+RTH  K
Sbjct: 725 QLINHQRTHTVK 736



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 69/321 (21%), Positives = 104/321 (32%), Gaps = 89/321 (27%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A +  L   +HQ        ++CSECG  +     ++SHQ  H               
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHT-------------- 538

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++C EC +       L  HQ  H  E      Y+C DC++ F     
Sbjct: 539 ---------GEKPYECSECGKAFGEKSSLATHQRTHTGEK----PYECRDCEKAFSQKSQ 585

Query: 155 WVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLE 214
              H++                                  +PYEC  C        E + 
Sbjct: 586 LNTHQRI-----------------------------HTGEKPYECSLCRKAFFEKSELIR 616

Query: 215 HQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG 274
           H  TH                      E+  E  E  +A  E           T      
Sbjct: 617 HLRTH--------------------TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFE 656

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHE 333
           C +C +    A +R+ H        +   P+ CS+C+++FS  ++L  H R H G   + 
Sbjct: 657 CSECGK----AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYR 712

Query: 334 CTTCSKVFKKAASLEQHLRLH 354
           C  C K F + + L  H R H
Sbjct: 713 CIECGKAFSQKSQLINHQRTH 733


>gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3
           [Homo sapiens]
          Length = 738

 Score =  224 bits (571), Expect = 2e-58
 Identities = 155/565 (27%), Positives = 228/565 (40%), Gaps = 97/565 (17%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELV 101
           S F  HH+       + CS+CG  ++   ++ SHQ  H                      
Sbjct: 248 SQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT--------------------- 286

Query: 102 PGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKA 161
              E P++CGEC +       L++H   H  E      Y C +C   F      + H++ 
Sbjct: 287 --GEKPYECGECGKAFSRKSHLISHWRTHTGEKP----YGCNECGRAFSEKSNLINHQRI 340

Query: 162 QHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFD 221
                                            +P+EC EC    +   + + H  TH  
Sbjct: 341 H-----------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTG 371

Query: 222 SLE---KEERNGLEEEEE-----DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQ 273
           +      + R    E+ E          E+  E  E  +A  E           T     
Sbjct: 372 TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPH 431

Query: 274 GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-H 332
           GC  C +    A +++ H  +     +   PF CS+C ++FS  ++L  H R H G   +
Sbjct: 432 GCIQCGK----AFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 333 ECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-R 391
           EC+ C K F +  SL  H R+H GE  Y+C +CG+ F  +  L++H+R HT    + C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 392 CGKTFSNMTKFLYHRRTHAGKSGAPPTGAT-APPAPAEPTPPPPPPAPPAQLPCPQCSKS 450
           CGK F   +    H+RTH G+          A    ++               C  C K+
Sbjct: 548 CGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKA 607

Query: 451 FASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFA 510
           F   S L RH R   G  E+ + C  C K F++   + NH R HTGE+PF+C  CGK F+
Sbjct: 608 FFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFS 665

Query: 511 SLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNK 570
             ++L  HQ THTG +PY C +C K F+Q S L  H+R+H              TG   +
Sbjct: 666 RKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIH--------------TG---E 708

Query: 571 SPYYCGTCGRWFRAMAGLRLHQRVH 595
            PY C  CG+ F   + L  HQR H
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTH 733



 Score =  222 bits (566), Expect = 8e-58
 Identities = 140/503 (27%), Positives = 220/503 (43%), Gaps = 75/503 (14%)

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           ++C EC +       L+ HQ  H+R+    I + C +C + FP    ++ H +       
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRD----IAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
                        + L      +    +PYEC EC    +     + H  TH      E+
Sbjct: 263 YNCSQCGKAFSQKSQL-TSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEK 317

Query: 228 RNGLEE--EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             G  E      ++ +  + + +   E   E                  C +C +    A
Sbjct: 318 PYGCNECGRAFSEKSNLINHQRIHTGEKPFE------------------CRECGK----A 355

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKA 344
            +R+    T H   + T PF CS C+++F   + L  H   H G   +EC+ C K F++ 
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
           +SL  H R H GE  + C+ CG+ F  +  L++H+  HT      C +CGK FS  ++ +
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+RTH G+             P E               C +C K+F+    L+ H+R 
Sbjct: 476 RHQRTHTGEK------------PYE---------------CSECGKAFSEKLSLTNHQRI 508

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  CGK F +  H+ +H RTHTGE+P++C  CGK F   ++L+ HQ THT
Sbjct: 509 HTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHT 566

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLH----------LRPVAFARAPRLPITGLY-NKSP 572
           G +PY+C DC K F+Q S L  H+R+H           R   F ++  +     +  + P
Sbjct: 567 GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 573 YYCGTCGRWFRAMAGLRLHQRVH 595
           Y C  C + FR  + L  HQR+H
Sbjct: 627 YECNECRKAFREKSSLINHQRIH 649



 Score =  160 bits (406), Expect = 3e-39
 Identities = 91/292 (31%), Positives = 134/292 (45%), Gaps = 47/292 (16%)

Query: 305 FHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVD 364
           + C + + S+  +  +  H        +EC+ C K F K  SL +H   H  +  + C +
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239

Query: 365 CGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAP 423
           CG+ F  +   + H R HT    + C +CGK FS  ++   H+RTH G+           
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---------- 289

Query: 424 PAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKK 483
             P E               C +C K+F+  S L  H R   G  E+ + C  CG+ F +
Sbjct: 290 --PYE---------------CGECGKAFSRKSHLISHWRTHTG--EKPYGCNECGRAFSE 330

Query: 484 LIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNL 543
             ++ NH R HTGE+PF+C  CGK F+  + L  H  THTG +P+ C DC K F + S L
Sbjct: 331 KSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSEL 390

Query: 544 QQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            +H+ +H              TG   + PY C  C + FR  + L  HQR H
Sbjct: 391 IRHQTIH--------------TG---EKPYECSECRKAFRERSSLINHQRTH 425



 Score =  159 bits (402), Expect = 8e-39
 Identities = 115/480 (23%), Positives = 183/480 (38%), Gaps = 81/480 (16%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCGEC 113
           C+ECG  ++    +++HQ  H      E     +A + ++  +          PF C +C
Sbjct: 321 CNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDC 380

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
            +      EL+ HQ  H  E      Y+C +C++ F      + H++             
Sbjct: 381 RKAFFEKSELIRHQTIHTGEKP----YECSECRKAFRERSSLINHQR------------- 423

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSL--------EK 225
                           +    +P+ C +C    +     + HQ TH            + 
Sbjct: 424 ----------------THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKA 467

Query: 226 EERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             R       +     E+  E  E  +A +E           T      C +C +    A
Sbjct: 468 FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK----A 523

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKA 344
             ++ H  +     +   P+ CS+C ++F   + L  H R H G   +EC  C K F + 
Sbjct: 524 FCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK 583

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFL 403
           + L  H R+H GE  Y C  C + F  +  L+ H R HT    + C  C K F   +  +
Sbjct: 584 SQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+R H G+             P E               C +C K+F+  S L  H+R 
Sbjct: 644 NHQRIHTGEK------------PFE---------------CSECGKAFSRKSHLIPHQRT 676

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  C K F +   + NH R HTGE+P++C  CGK F+  + L  HQ THT
Sbjct: 677 HTG--EKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHT 734



 Score =  117 bits (292), Expect = 4e-26
 Identities = 89/372 (23%), Positives = 145/372 (38%), Gaps = 54/372 (14%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHML-----AVSEEEALTTQNVGLEPELVPGAEGPFQCG 111
           + CSEC   +     +++HQ  H        +   +A + ++  +  ++    E PF C 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           +C +      +L+ HQ  H  E      Y+C +C + F S +L + + +  H        
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKP----YECSECGKAF-SEKLSLTNHQRIHTGE----- 512

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKE----- 226
                                  +PY C EC          + HQ TH      E     
Sbjct: 513 -----------------------KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 227 ----ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQ 282
               E++ L   +      E+  E  + E+A ++           T      C  C +  
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 283 PSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVF 341
                  +H RT     +   P+ C++C+++F   + L  H R H G    EC+ C K F
Sbjct: 609 FEKSELIRHLRTH----TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF 664

Query: 342 KKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMT 400
            + + L  H R H GE  Y C +C + F  +  LV H+R HT    +RC  CGK FS  +
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 401 KFLYHRRTHAGK 412
           + + H+RTH  K
Sbjct: 725 QLINHQRTHTVK 736



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 69/321 (21%), Positives = 104/321 (32%), Gaps = 89/321 (27%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A +  L   +HQ        ++CSECG  +     ++SHQ  H               
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHT-------------- 538

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++C EC +       L  HQ  H  E      Y+C DC++ F     
Sbjct: 539 ---------GEKPYECSECGKAFGEKSSLATHQRTHTGEK----PYECRDCEKAFSQKSQ 585

Query: 155 WVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLE 214
              H++                                  +PYEC  C        E + 
Sbjct: 586 LNTHQRI-----------------------------HTGEKPYECSLCRKAFFEKSELIR 616

Query: 215 HQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG 274
           H  TH                      E+  E  E  +A  E           T      
Sbjct: 617 HLRTH--------------------TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFE 656

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHE 333
           C +C +    A +R+ H        +   P+ CS+C+++FS  ++L  H R H G   + 
Sbjct: 657 CSECGK----AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYR 712

Query: 334 CTTCSKVFKKAASLEQHLRLH 354
           C  C K F + + L  H R H
Sbjct: 713 CIECGKAFSQKSQLINHQRTH 733


>gi|188497655 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  224 bits (571), Expect = 2e-58
 Identities = 155/565 (27%), Positives = 228/565 (40%), Gaps = 97/565 (17%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELV 101
           S F  HH+       + CS+CG  ++   ++ SHQ  H                      
Sbjct: 248 SQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT--------------------- 286

Query: 102 PGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKA 161
              E P++CGEC +       L++H   H  E      Y C +C   F      + H++ 
Sbjct: 287 --GEKPYECGECGKAFSRKSHLISHWRTHTGEKP----YGCNECGRAFSEKSNLINHQRI 340

Query: 162 QHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFD 221
                                            +P+EC EC    +   + + H  TH  
Sbjct: 341 H-----------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTG 371

Query: 222 SLE---KEERNGLEEEEE-----DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQ 273
           +      + R    E+ E          E+  E  E  +A  E           T     
Sbjct: 372 TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPH 431

Query: 274 GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-H 332
           GC  C +    A +++ H  +     +   PF CS+C ++FS  ++L  H R H G   +
Sbjct: 432 GCIQCGK----AFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 333 ECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-R 391
           EC+ C K F +  SL  H R+H GE  Y+C +CG+ F  +  L++H+R HT    + C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 392 CGKTFSNMTKFLYHRRTHAGKSGAPPTGAT-APPAPAEPTPPPPPPAPPAQLPCPQCSKS 450
           CGK F   +    H+RTH G+          A    ++               C  C K+
Sbjct: 548 CGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKA 607

Query: 451 FASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFA 510
           F   S L RH R   G  E+ + C  C K F++   + NH R HTGE+PF+C  CGK F+
Sbjct: 608 FFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFS 665

Query: 511 SLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNK 570
             ++L  HQ THTG +PY C +C K F+Q S L  H+R+H              TG   +
Sbjct: 666 RKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIH--------------TG---E 708

Query: 571 SPYYCGTCGRWFRAMAGLRLHQRVH 595
            PY C  CG+ F   + L  HQR H
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTH 733



 Score =  222 bits (566), Expect = 8e-58
 Identities = 140/503 (27%), Positives = 220/503 (43%), Gaps = 75/503 (14%)

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           ++C EC +       L+ HQ  H+R+    I + C +C + FP    ++ H +       
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRD----IAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
                        + L      +    +PYEC EC    +     + H  TH      E+
Sbjct: 263 YNCSQCGKAFSQKSQL-TSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEK 317

Query: 228 RNGLEE--EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             G  E      ++ +  + + +   E   E                  C +C +    A
Sbjct: 318 PYGCNECGRAFSEKSNLINHQRIHTGEKPFE------------------CRECGK----A 355

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKA 344
            +R+    T H   + T PF CS C+++F   + L  H   H G   +EC+ C K F++ 
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
           +SL  H R H GE  + C+ CG+ F  +  L++H+  HT      C +CGK FS  ++ +
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+RTH G+             P E               C +C K+F+    L+ H+R 
Sbjct: 476 RHQRTHTGEK------------PYE---------------CSECGKAFSEKLSLTNHQRI 508

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  CGK F +  H+ +H RTHTGE+P++C  CGK F   ++L+ HQ THT
Sbjct: 509 HTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHT 566

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLH----------LRPVAFARAPRLPITGLY-NKSP 572
           G +PY+C DC K F+Q S L  H+R+H           R   F ++  +     +  + P
Sbjct: 567 GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 573 YYCGTCGRWFRAMAGLRLHQRVH 595
           Y C  C + FR  + L  HQR+H
Sbjct: 627 YECNECRKAFREKSSLINHQRIH 649



 Score =  160 bits (406), Expect = 3e-39
 Identities = 91/292 (31%), Positives = 134/292 (45%), Gaps = 47/292 (16%)

Query: 305 FHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVD 364
           + C + + S+  +  +  H        +EC+ C K F K  SL +H   H  +  + C +
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239

Query: 365 CGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAP 423
           CG+ F  +   + H R HT    + C +CGK FS  ++   H+RTH G+           
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---------- 289

Query: 424 PAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKK 483
             P E               C +C K+F+  S L  H R   G  E+ + C  CG+ F +
Sbjct: 290 --PYE---------------CGECGKAFSRKSHLISHWRTHTG--EKPYGCNECGRAFSE 330

Query: 484 LIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNL 543
             ++ NH R HTGE+PF+C  CGK F+  + L  H  THTG +P+ C DC K F + S L
Sbjct: 331 KSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSEL 390

Query: 544 QQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            +H+ +H              TG   + PY C  C + FR  + L  HQR H
Sbjct: 391 IRHQTIH--------------TG---EKPYECSECRKAFRERSSLINHQRTH 425



 Score =  159 bits (402), Expect = 8e-39
 Identities = 115/480 (23%), Positives = 183/480 (38%), Gaps = 81/480 (16%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCGEC 113
           C+ECG  ++    +++HQ  H      E     +A + ++  +          PF C +C
Sbjct: 321 CNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDC 380

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
            +      EL+ HQ  H  E      Y+C +C++ F      + H++             
Sbjct: 381 RKAFFEKSELIRHQTIHTGEKP----YECSECRKAFRERSSLINHQR------------- 423

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSL--------EK 225
                           +    +P+ C +C    +     + HQ TH            + 
Sbjct: 424 ----------------THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKA 467

Query: 226 EERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             R       +     E+  E  E  +A +E           T      C +C +    A
Sbjct: 468 FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK----A 523

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKA 344
             ++ H  +     +   P+ CS+C ++F   + L  H R H G   +EC  C K F + 
Sbjct: 524 FCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK 583

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFL 403
           + L  H R+H GE  Y C  C + F  +  L+ H R HT    + C  C K F   +  +
Sbjct: 584 SQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+R H G+             P E               C +C K+F+  S L  H+R 
Sbjct: 644 NHQRIHTGEK------------PFE---------------CSECGKAFSRKSHLIPHQRT 676

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  C K F +   + NH R HTGE+P++C  CGK F+  + L  HQ THT
Sbjct: 677 HTG--EKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHT 734



 Score =  117 bits (292), Expect = 4e-26
 Identities = 89/372 (23%), Positives = 145/372 (38%), Gaps = 54/372 (14%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHML-----AVSEEEALTTQNVGLEPELVPGAEGPFQCG 111
           + CSEC   +     +++HQ  H        +   +A + ++  +  ++    E PF C 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           +C +      +L+ HQ  H  E      Y+C +C + F S +L + + +  H        
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKP----YECSECGKAF-SEKLSLTNHQRIHTGE----- 512

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKE----- 226
                                  +PY C EC          + HQ TH      E     
Sbjct: 513 -----------------------KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 227 ----ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQ 282
               E++ L   +      E+  E  + E+A ++           T      C  C +  
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 283 PSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVF 341
                  +H RT     +   P+ C++C+++F   + L  H R H G    EC+ C K F
Sbjct: 609 FEKSELIRHLRTH----TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF 664

Query: 342 KKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMT 400
            + + L  H R H GE  Y C +C + F  +  LV H+R HT    +RC  CGK FS  +
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 401 KFLYHRRTHAGK 412
           + + H+RTH  K
Sbjct: 725 QLINHQRTHTVK 736



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 69/321 (21%), Positives = 104/321 (32%), Gaps = 89/321 (27%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A +  L   +HQ        ++CSECG  +     ++SHQ  H               
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHT-------------- 538

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++C EC +       L  HQ  H  E      Y+C DC++ F     
Sbjct: 539 ---------GEKPYECSECGKAFGEKSSLATHQRTHTGEK----PYECRDCEKAFSQKSQ 585

Query: 155 WVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLE 214
              H++                                  +PYEC  C        E + 
Sbjct: 586 LNTHQRI-----------------------------HTGEKPYECSLCRKAFFEKSELIR 616

Query: 215 HQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG 274
           H  TH                      E+  E  E  +A  E           T      
Sbjct: 617 HLRTH--------------------TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFE 656

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHE 333
           C +C +    A +R+ H        +   P+ CS+C+++FS  ++L  H R H G   + 
Sbjct: 657 CSECGK----AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYR 712

Query: 334 CTTCSKVFKKAASLEQHLRLH 354
           C  C K F + + L  H R H
Sbjct: 713 CIECGKAFSQKSQLINHQRTH 733


>gi|188497653 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  224 bits (571), Expect = 2e-58
 Identities = 155/565 (27%), Positives = 228/565 (40%), Gaps = 97/565 (17%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELV 101
           S F  HH+       + CS+CG  ++   ++ SHQ  H                      
Sbjct: 248 SQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT--------------------- 286

Query: 102 PGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKA 161
              E P++CGEC +       L++H   H  E      Y C +C   F      + H++ 
Sbjct: 287 --GEKPYECGECGKAFSRKSHLISHWRTHTGEKP----YGCNECGRAFSEKSNLINHQRI 340

Query: 162 QHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFD 221
                                            +P+EC EC    +   + + H  TH  
Sbjct: 341 H-----------------------------TGEKPFECRECGKAFSRKSQLVTHHRTHTG 371

Query: 222 SLE---KEERNGLEEEEE-----DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQ 273
           +      + R    E+ E          E+  E  E  +A  E           T     
Sbjct: 372 TKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPH 431

Query: 274 GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-H 332
           GC  C +    A +++ H  +     +   PF CS+C ++FS  ++L  H R H G   +
Sbjct: 432 GCIQCGK----AFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPY 487

Query: 333 ECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-R 391
           EC+ C K F +  SL  H R+H GE  Y+C +CG+ F  +  L++H+R HT    + C  
Sbjct: 488 ECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSE 547

Query: 392 CGKTFSNMTKFLYHRRTHAGKSGAPPTGAT-APPAPAEPTPPPPPPAPPAQLPCPQCSKS 450
           CGK F   +    H+RTH G+          A    ++               C  C K+
Sbjct: 548 CGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKA 607

Query: 451 FASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFA 510
           F   S L RH R   G  E+ + C  C K F++   + NH R HTGE+PF+C  CGK F+
Sbjct: 608 FFEKSELIRHLRTHTG--EKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFS 665

Query: 511 SLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNK 570
             ++L  HQ THTG +PY C +C K F+Q S L  H+R+H              TG   +
Sbjct: 666 RKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIH--------------TG---E 708

Query: 571 SPYYCGTCGRWFRAMAGLRLHQRVH 595
            PY C  CG+ F   + L  HQR H
Sbjct: 709 KPYRCIECGKAFSQKSQLINHQRTH 733



 Score =  222 bits (566), Expect = 8e-58
 Identities = 140/503 (27%), Positives = 220/503 (43%), Gaps = 75/503 (14%)

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           ++C EC +       L+ HQ  H+R+    I + C +C + FP    ++ H +       
Sbjct: 207 YECSECRKRFSKKPSLIKHQSRHIRD----IAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
                        + L      +    +PYEC EC    +     + H  TH      E+
Sbjct: 263 YNCSQCGKAFSQKSQL-TSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTH----TGEK 317

Query: 228 RNGLEE--EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             G  E      ++ +  + + +   E   E                  C +C +    A
Sbjct: 318 PYGCNECGRAFSEKSNLINHQRIHTGEKPFE------------------CRECGK----A 355

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKA 344
            +R+    T H   + T PF CS C+++F   + L  H   H G   +EC+ C K F++ 
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRER 415

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
           +SL  H R H GE  + C+ CG+ F  +  L++H+  HT      C +CGK FS  ++ +
Sbjct: 416 SSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLV 475

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+RTH G+             P E               C +C K+F+    L+ H+R 
Sbjct: 476 RHQRTHTGEK------------PYE---------------CSECGKAFSEKLSLTNHQRI 508

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  CGK F +  H+ +H RTHTGE+P++C  CGK F   ++L+ HQ THT
Sbjct: 509 HTG--EKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHT 566

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLH----------LRPVAFARAPRLPITGLY-NKSP 572
           G +PY+C DC K F+Q S L  H+R+H           R   F ++  +     +  + P
Sbjct: 567 GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 573 YYCGTCGRWFRAMAGLRLHQRVH 595
           Y C  C + FR  + L  HQR+H
Sbjct: 627 YECNECRKAFREKSSLINHQRIH 649



 Score =  160 bits (406), Expect = 3e-39
 Identities = 91/292 (31%), Positives = 134/292 (45%), Gaps = 47/292 (16%)

Query: 305 FHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVD 364
           + C + + S+  +  +  H        +EC+ C K F K  SL +H   H  +  + C +
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239

Query: 365 CGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAP 423
           CG+ F  +   + H R HT    + C +CGK FS  ++   H+RTH G+           
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEK---------- 289

Query: 424 PAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKK 483
             P E               C +C K+F+  S L  H R   G  E+ + C  CG+ F +
Sbjct: 290 --PYE---------------CGECGKAFSRKSHLISHWRTHTG--EKPYGCNECGRAFSE 330

Query: 484 LIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNL 543
             ++ NH R HTGE+PF+C  CGK F+  + L  H  THTG +P+ C DC K F + S L
Sbjct: 331 KSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSEL 390

Query: 544 QQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            +H+ +H              TG   + PY C  C + FR  + L  HQR H
Sbjct: 391 IRHQTIH--------------TG---EKPYECSECRKAFRERSSLINHQRTH 425



 Score =  159 bits (402), Expect = 8e-39
 Identities = 115/480 (23%), Positives = 183/480 (38%), Gaps = 81/480 (16%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCGEC 113
           C+ECG  ++    +++HQ  H      E     +A + ++  +          PF C +C
Sbjct: 321 CNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDC 380

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
            +      EL+ HQ  H  E      Y+C +C++ F      + H++             
Sbjct: 381 RKAFFEKSELIRHQTIHTGEKP----YECSECRKAFRERSSLINHQR------------- 423

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSL--------EK 225
                           +    +P+ C +C    +     + HQ TH            + 
Sbjct: 424 ----------------THTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKA 467

Query: 226 EERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
             R       +     E+  E  E  +A +E           T      C +C +    A
Sbjct: 468 FSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGK----A 523

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKA 344
             ++ H  +     +   P+ CS+C ++F   + L  H R H G   +EC  C K F + 
Sbjct: 524 FCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQK 583

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFL 403
           + L  H R+H GE  Y C  C + F  +  L+ H R HT    + C  C K F   +  +
Sbjct: 584 SQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLI 643

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+R H G+             P E               C +C K+F+  S L  H+R 
Sbjct: 644 NHQRIHTGEK------------PFE---------------CSECGKAFSRKSHLIPHQRT 676

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+ + C  C K F +   + NH R HTGE+P++C  CGK F+  + L  HQ THT
Sbjct: 677 HTG--EKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHT 734



 Score =  117 bits (292), Expect = 4e-26
 Identities = 89/372 (23%), Positives = 145/372 (38%), Gaps = 54/372 (14%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHML-----AVSEEEALTTQNVGLEPELVPGAEGPFQCG 111
           + CSEC   +     +++HQ  H        +   +A + ++  +  ++    E PF C 
Sbjct: 403 YECSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICS 462

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           +C +      +L+ HQ  H  E      Y+C +C + F S +L + + +  H        
Sbjct: 463 KCGKAFSRKSQLVRHQRTHTGEKP----YECSECGKAF-SEKLSLTNHQRIHTGE----- 512

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKE----- 226
                                  +PY C EC          + HQ TH      E     
Sbjct: 513 -----------------------KPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECG 549

Query: 227 ----ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQ 282
               E++ L   +      E+  E  + E+A ++           T      C  C +  
Sbjct: 550 KAFGEKSSLATHQRT-HTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAF 608

Query: 283 PSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVF 341
                  +H RT     +   P+ C++C+++F   + L  H R H G    EC+ C K F
Sbjct: 609 FEKSELIRHLRTH----TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF 664

Query: 342 KKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMT 400
            + + L  H R H GE  Y C +C + F  +  LV H+R HT    +RC  CGK FS  +
Sbjct: 665 SRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKS 724

Query: 401 KFLYHRRTHAGK 412
           + + H+RTH  K
Sbjct: 725 QLINHQRTHTVK 736



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 69/321 (21%), Positives = 104/321 (32%), Gaps = 89/321 (27%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A +  L   +HQ        ++CSECG  +     ++SHQ  H               
Sbjct: 493 GKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHT-------------- 538

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++C EC +       L  HQ  H  E      Y+C DC++ F     
Sbjct: 539 ---------GEKPYECSECGKAFGEKSSLATHQRTHTGEK----PYECRDCEKAFSQKSQ 585

Query: 155 WVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLE 214
              H++                                  +PYEC  C        E + 
Sbjct: 586 LNTHQRI-----------------------------HTGEKPYECSLCRKAFFEKSELIR 616

Query: 215 HQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG 274
           H  TH                      E+  E  E  +A  E           T      
Sbjct: 617 HLRTH--------------------TGEKPYECNECRKAFREKSSLINHQRIHTGEKPFE 656

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHE 333
           C +C +    A +R+ H        +   P+ CS+C+++FS  ++L  H R H G   + 
Sbjct: 657 CSECGK----AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHTGEKPYR 712

Query: 334 CTTCSKVFKKAASLEQHLRLH 354
           C  C K F + + L  H R H
Sbjct: 713 CIECGKAFSQKSQLINHQRTH 733


>gi|34419633 zinc finger protein 135 [Homo sapiens]
          Length = 658

 Score =  222 bits (565), Expect = 1e-57
 Identities = 130/412 (31%), Positives = 193/412 (46%), Gaps = 48/412 (11%)

Query: 192 VKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDE 251
           VK +PY+C EC    +     +EH  TH                E   E  E  +   + 
Sbjct: 209 VKEKPYKCQECGKAFSHSSALIEHHRTHTG--------------ERPYECHECLKGFRNS 254

Query: 252 EAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQ 311
            A+ +      G           C  C +         QH+RT     +   P+ CS+C 
Sbjct: 255 SALTKHQRIHTGEKPYK------CTQCGRTFNQIAPLIQHQRTH----TGEKPYECSECG 304

Query: 312 RSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFG 370
           +SFS  +    H R H G   +EC+ C K F+++  L QHLR+H GE  Y C +CG+ F 
Sbjct: 305 KSFSFRSSFSQHERTHTGEKPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFS 364

Query: 371 TELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEP 429
              +L  H+R HT    + C  CGK F+ +T  + H+RTH G+      G          
Sbjct: 365 HSSSLTKHQRIHTGEKPYECHECGKAFTQITPLIQHQRTHTGEKPYE-CGECGKAFSQST 423

Query: 430 TPPPPPPAPPAQLP--CPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHV 487
                      + P  C +C K+F+ +S LS+H R   G  E+ + C  CGK F++  H+
Sbjct: 424 LLTEHRRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTG--EKPYECSQCGKAFRQSTHL 481

Query: 488 RNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHR 547
             H R HTGE+P++C+ CGK F+  ++L++HQ  HTG +PY+C  CG+ F+Q + L QH+
Sbjct: 482 TQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQ 541

Query: 548 RLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           R+H              TG   + PY C  CGR F   + L  HQR+H + +
Sbjct: 542 RIH--------------TG---EKPYECNQCGRAFSQSSLLIEHQRIHTKEK 576



 Score =  214 bits (544), Expect = 3e-55
 Identities = 148/549 (26%), Positives = 220/549 (40%), Gaps = 116/549 (21%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + C ECG  ++    ++ H   H                         E P++C EC + 
Sbjct: 214 YKCQECGKAFSHSSALIEHHRTHT-----------------------GERPYECHECLKG 250

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
             +   L  HQ  H  E      Y+C  C   F      + H++                
Sbjct: 251 FRNSSALTKHQRIHTGEKP----YKCTQCGRTFNQIAPLIQHQR---------------- 290

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTH-----FDSLE--KEERN 229
                        +    +PYEC EC    +    F +H+ TH     ++  E  K  R 
Sbjct: 291 -------------THTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECSECGKAFRQ 337

Query: 230 GLEEEEEDDEEDEEDDEEM-EDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGAR 288
            +   +       E   +  E  +A +            T      C +C +        
Sbjct: 338 SIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECGKAFTQITPL 397

Query: 289 RQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASL 347
            QH+RT     +   P+ C +C ++FS +  L  H R H G   + C  C K F  ++SL
Sbjct: 398 IQHQRTH----TGEKPYECGECGKAFSQSTLLTEHRRIHTGEKPYGCNECGKTFSHSSSL 453

Query: 348 EQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHR 406
            QH R H GE  Y C  CG+ F     L  H+R HT    + C  CGK FS+ +    H+
Sbjct: 454 SQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQ 513

Query: 407 RTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHG 466
           R H G+             P E               C QC ++F+  + L +H+R   G
Sbjct: 514 RIHTGEK------------PYE---------------CNQCGRAFSQLAPLIQHQRIHTG 546

Query: 467 PPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGAR 526
             E+ + C  CG+ F +   +  H R HT E+P+ C+ CGK+F+  ++LS+H+ THTG +
Sbjct: 547 --EKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEK 604

Query: 527 PYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMA 586
           PY+C DCGK F QS++L QHRR+H              TG   + PY C  CG+ F   +
Sbjct: 605 PYECHDCGKSFRQSTHLTQHRRIH--------------TG---EKPYACRDCGKAFTHSS 647

Query: 587 GLRLHQRVH 595
            L  HQR H
Sbjct: 648 SLTKHQRTH 656



 Score =  196 bits (497), Expect = 8e-50
 Identities = 129/475 (27%), Positives = 192/475 (40%), Gaps = 93/475 (19%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCG 111
           + C++CG  +N +  ++ HQ  H      E     ++ + ++   + E     E P++C 
Sbjct: 270 YKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECS 329

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           EC +          H   HLR    +  YQC +C + F        H++           
Sbjct: 330 ECGKAFRQS----IHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIH--------- 376

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGL 231
                                  +PYEC EC          ++HQ TH          G 
Sbjct: 377 --------------------TGEKPYECHECGKAFTQITPLIQHQRTH---------TGE 407

Query: 232 EEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQH 291
           +  E  +         +  E      G+   G +E        CG    H  S     QH
Sbjct: 408 KPYECGECGKAFSQSTLLTEHRRIHTGEKPYGCNE--------CGKTFSHSSSLS---QH 456

Query: 292 RRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQH 350
            RT     +   P+ CSQC ++F  +  L  H R H G   +EC  C K F  ++SL +H
Sbjct: 457 ERTH----TGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKH 512

Query: 351 LRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTH 409
            R+H GE  Y C  CGR F     L+ H+R HT    + C +CG+ FS  +  + H+R H
Sbjct: 513 QRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIH 572

Query: 410 AGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPE 469
             +    P G                        C +C KSF+ +S LS+H R   G  E
Sbjct: 573 TKEK---PYG------------------------CNECGKSFSHSSSLSQHERTHTG--E 603

Query: 470 RRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTG 524
           + + C  CGK F++  H+  H R HTGE+P+ C  CGK F   ++L++HQ THTG
Sbjct: 604 KPYECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCGKAFTHSSSLTKHQRTHTG 658



 Score = 86.3 bits (212), Expect = 8e-17
 Identities = 51/130 (39%), Positives = 67/130 (51%), Gaps = 21/130 (16%)

Query: 468 PERR--HRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGA 525
           PER+  H  G  GK  K  ++V    +T   E+P++C  CGK F+  + L  H  THTG 
Sbjct: 182 PERQSPHTWGTRGKREKPDLNVLQ--KTCVKEKPYKCQECGKAFSHSSALIEHHRTHTGE 239

Query: 526 RPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAM 585
           RPY+C +C K F  SS L +H+R+H              TG   + PY C  CGR F  +
Sbjct: 240 RPYECHECLKGFRNSSALTKHQRIH--------------TG---EKPYKCTQCGRTFNQI 282

Query: 586 AGLRLHQRVH 595
           A L  HQR H
Sbjct: 283 APLIQHQRTH 292



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 39/190 (20%), Positives = 63/190 (33%), Gaps = 46/190 (24%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EAL 89
           G+A + S     HQ        + C++CG  ++ L  ++ HQ  H      E      A 
Sbjct: 500 GKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAF 559

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
           +  ++ +E + +   E P+ C EC +       L  H+  H  E      Y+C DC + F
Sbjct: 560 SQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKP----YECHDCGKSF 615

Query: 150 PSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATP 209
                   HR+                                  +PY C +C       
Sbjct: 616 RQSTHLTQHRRI-----------------------------HTGEKPYACRDCGKAFTHS 646

Query: 210 EEFLEHQGTH 219
               +HQ TH
Sbjct: 647 SSLTKHQRTH 656


>gi|222418585 zinc finger protein 814 [Homo sapiens]
          Length = 855

 Score =  221 bits (562), Expect = 2e-57
 Identities = 155/578 (26%), Positives = 221/578 (38%), Gaps = 131/578 (22%)

Query: 43  GEALASSLFFQHHQFM-------CSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVG 95
           G++ +  + F +HQ +       C ECG  ++      +HQ  H                
Sbjct: 275 GKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHT--------------- 319

Query: 96  LEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELW 155
                    + P++CGEC +          HQ  H  +      Y+C +C + F     +
Sbjct: 320 --------GKRPYECGECGKSFSKYASFSNHQRVHTEKK----HYECGECGKSFSKYVSF 367

Query: 156 VAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEH 215
             H++                                   PYEC EC    +    F  H
Sbjct: 368 SNHQRVH-----------------------------TGKRPYECGECGKSFSKYASFSNH 398

Query: 216 QGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG- 274
           Q  H D    E      E  +   +     +           G +  G   S+ G  +  
Sbjct: 399 QRVHTDKKHYE----CGECGKSFSQKSSLIQHQRFHTGEKPYGCEECGKSFSSEGHLRSH 454

Query: 275 -----------CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAH 323
                      CG+C +      +   H+R      S   P+ C +C +SFS    L  H
Sbjct: 455 QRVHAGERPFKCGECVKSFSHKRSLVHHQRVH----SGERPYQCGECGKSFSQKGNLVLH 510

Query: 324 GRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAH 382
            R H G   +EC  C K F     L  H ++H G+  Y C +CG+ F  + TL+ H+R H
Sbjct: 511 QRVHTGARPYECGECGKSFSSKGHLRNHQQIHTGDRLYECGECGKSFSHKGTLILHQRVH 570

Query: 383 TANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQ 441
                + C  CGK+FS++     H+R H G+             P E             
Sbjct: 571 PRERSYGCGECGKSFSSIGHLRSHQRVHTGER------------PYE------------- 605

Query: 442 LPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQ 501
             C +C KSF+    L  H+R   G  ER ++CG CGK F +  H+RNH R HT ERPF+
Sbjct: 606 --CGECGKSFSHKRSLVHHQRMHTG--ERPYKCGDCGKSFNEKGHLRNHQRVHTTERPFK 661

Query: 502 CHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPR 561
           C  CGK F+   NL  HQ  HTG RPY C +CGK F + S+L  H+R+H           
Sbjct: 662 CGECGKCFSHKGNLILHQHGHTGERPYVCRECGKLFKKKSHLLVHQRIH----------- 710

Query: 562 LPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
                   + PY C  C ++FR    L  HQRVH   R
Sbjct: 711 ------NGEKPYACEACQKFFRNKYQLIAHQRVHTGER 742



 Score =  214 bits (546), Expect = 2e-55
 Identities = 153/570 (26%), Positives = 229/570 (40%), Gaps = 118/570 (20%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVS---EE--EAL 89
           G++ +    F +HQ        + C ECG  ++    ++ HQ  H        EE  ++ 
Sbjct: 386 GKSFSKYASFSNHQRVHTDKKHYECGECGKSFSQKSSLIQHQRFHTGEKPYGCEECGKSF 445

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
           +++      + V   E PF+CGEC +       L+ HQ  H  E      YQC +C + F
Sbjct: 446 SSEGHLRSHQRVHAGERPFKCGECVKSFSHKRSLVHHQRVHSGERP----YQCGECGKSF 501

Query: 150 PSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATP 209
                 V H++  H  A                             PYEC EC    ++ 
Sbjct: 502 SQKGNLVLHQRV-HTGA----------------------------RPYECGECGKSFSSK 532

Query: 210 EEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTA 269
                HQ  H                      +   E  E  ++ +  G   +       
Sbjct: 533 GHLRNHQQIH--------------------TGDRLYECGECGKSFSHKGTLILHQRVHPR 572

Query: 270 GWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG 329
             + GCG+C +   S G  R H+R      +   P+ C +C +SFS    L  H R H G
Sbjct: 573 ERSYGCGECGKSFSSIGHLRSHQRVH----TGERPYECGECGKSFSHKRSLVHHQRMHTG 628

Query: 330 GT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLH 388
              ++C  C K F +   L  H R+H  E  + C +CG+ F  +  L+ H+  HT    +
Sbjct: 629 ERPYKCGDCGKSFNEKGHLRNHQRVHTTERPFKCGECGKCFSHKGNLILHQHGHTGERPY 688

Query: 389 RCR-CGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQC 447
            CR CGK F   +  L H+R H G+                               C  C
Sbjct: 689 VCRECGKLFKKKSHLLVHQRIHNGEK---------------------------PYACEAC 721

Query: 448 SKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGK 507
            K F +  +L  H+R   G  ER + C  CGK F        H R HTGE+P++C  CGK
Sbjct: 722 QKFFRNKYQLIAHQRVHTG--ERPYECNDCGKSFTHSSTFCVHKRIHTGEKPYECSECGK 779

Query: 508 TFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGL 567
           +FA  ++ ++H+  HTG +PY+C +CGK F +SS+L +H+R+H              TG 
Sbjct: 780 SFAESSSFTKHKRVHTGEKPYECSECGKSFAESSSLTKHKRVH--------------TG- 824

Query: 568 YNKSPYYCGTCGRWFRAMAGLRLHQRVHAR 597
             + PY C  CG+ F   + L +HQ  H R
Sbjct: 825 --EKPYKCEKCGKLFNKKSHLLVHQSSHWR 852



 Score =  199 bits (506), Expect = 7e-51
 Identities = 113/328 (34%), Positives = 153/328 (46%), Gaps = 52/328 (15%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTH-E 333
           CG+C +      +   H+R      +   P+ C +C +SFS       H R H    H E
Sbjct: 298 CGECGKSFSKYVSFSNHQRVH----TGKRPYECGECGKSFSKYASFSNHQRVHTEKKHYE 353

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RC 392
           C  C K F K  S   H R+H G+  Y C +CG+ F    +   H+R HT    + C  C
Sbjct: 354 CGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVHTDKKHYECGEC 413

Query: 393 GKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFA 452
           GK+FS  +  + H+R H G+    P G                        C +C KSF+
Sbjct: 414 GKSFSQKSSLIQHQRFHTGEK---PYG------------------------CEECGKSFS 446

Query: 453 SASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASL 512
           S   L  H+R   G  ER  +CG C K F     + +H R H+GERP+QC  CGK+F+  
Sbjct: 447 SEGHLRSHQRVHAG--ERPFKCGECVKSFSHKRSLVHHQRVHSGERPYQCGECGKSFSQK 504

Query: 513 ANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSP 572
            NL  HQ  HTGARPY+C +CGK F+   +L+ H+++H          RL          
Sbjct: 505 GNLVLHQRVHTGARPYECGECGKSFSSKGHLRNHQQIH-------TGDRL---------- 547

Query: 573 YYCGTCGRWFRAMAGLRLHQRVHARART 600
           Y CG CG+ F     L LHQRVH R R+
Sbjct: 548 YECGECGKSFSHKGTLILHQRVHPRERS 575



 Score =  196 bits (499), Expect = 4e-50
 Identities = 141/547 (25%), Positives = 204/547 (37%), Gaps = 134/547 (24%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           ++C ECG  ++    + +HQ  H                         E   +CGEC + 
Sbjct: 242 YVCCECGKSFSKYASLSNHQRVH------------------------TEKKHECGECGKS 277

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
                    HQ  H  +     +++C +C + F     +  H++                
Sbjct: 278 FSKYVSFSNHQRVHTEK-----KHECGECGKSFSKYVSFSNHQRVH-------------- 318

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE 236
                              PYEC EC    +    F  HQ  H +    E          
Sbjct: 319 ---------------TGKRPYECGECGKSFSKYASFSNHQRVHTEKKHYE---------- 353

Query: 237 DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAH 296
                                                 CG+C +      +   H+R   
Sbjct: 354 --------------------------------------CGECGKSFSKYVSFSNHQRVH- 374

Query: 297 SPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTH-ECTTCSKVFKKAASLEQHLRLHR 355
              +   P+ C +C +SFS       H R H    H EC  C K F + +SL QH R H 
Sbjct: 375 ---TGKRPYECGECGKSFSKYASFSNHQRVHTDKKHYECGECGKSFSQKSSLIQHQRFHT 431

Query: 356 GEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSG 414
           GE  Y C +CG+ F +E  L +H+R H      +C  C K+FS+    ++H+R H+G+  
Sbjct: 432 GEKPYGCEECGKSFSSEGHLRSHQRVHAGERPFKCGECVKSFSHKRSLVHHQRVHSGERP 491

Query: 415 APPTGATAPPAPAEPTPPPPPPAPPAQLP--CPQCSKSFASASRLSRHRRAVHGPPERRH 472
               G        +              P  C +C KSF+S   L  H++   G  +R +
Sbjct: 492 YQ-CGECGKSFSQKGNLVLHQRVHTGARPYECGECGKSFSSKGHLRNHQQIHTG--DRLY 548

Query: 473 RCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLD 532
            CG CGK F     +  H R H  ER + C  CGK+F+S+ +L  HQ  HTG RPY+C +
Sbjct: 549 ECGECGKSFSHKGTLILHQRVHPRERSYGCGECGKSFSSIGHLRSHQRVHTGERPYECGE 608

Query: 533 CGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQ 592
           CGK F+   +L  H+R+H              TG   + PY CG CG+ F     LR HQ
Sbjct: 609 CGKSFSHKRSLVHHQRMH--------------TG---ERPYKCGDCGKSFNEKGHLRNHQ 651

Query: 593 RVHARAR 599
           RVH   R
Sbjct: 652 RVHTTER 658



 Score =  189 bits (479), Expect = 9e-48
 Identities = 135/437 (30%), Positives = 190/437 (43%), Gaps = 73/437 (16%)

Query: 181 TPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSL--------EKEERNGLE 232
           TP+   SP      + + C  C  +        +HQGTH             K   +G  
Sbjct: 81  TPMAGVSPK-----KAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNF 135

Query: 233 EEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGD-----ESTAGWAQGCGDCPQHQPSAGA 287
            + +++   E+      +E   A+     V G+     ES   +    G   Q     G 
Sbjct: 136 HQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDFLPRSGLLQQEASHTGE 195

Query: 288 RRQHRRTAHSP--ASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKA 344
           +   +    SP      H + C +  + FS+ + L  H R       + C  C K F K 
Sbjct: 196 KSNSKTECVSPIQCGGAH-YSCGESMKHFSTKHILSQHQRLLTREECYVCCECGKSFSKY 254

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
           ASL  H R+H  E ++ C +CG+ F   ++   H+R HT    H C  CGK+FS    F 
Sbjct: 255 ASLSNHQRVHT-EKKHECGECGKSFSKYVSFSNHQRVHTEKK-HECGECGKSFSKYVSFS 312

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+R H GK             P E               C +C KSF+  +  S H+R 
Sbjct: 313 NHQRVHTGKR------------PYE---------------CGECGKSFSKYASFSNHQR- 344

Query: 464 VHGPPERRH-RCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTH 522
           VH   E++H  CG CGK F K +   NH R HTG+RP++C  CGK+F+  A+ S HQ  H
Sbjct: 345 VH--TEKKHYECGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVH 402

Query: 523 TGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWF 582
           T  + Y+C +CGK F+Q S+L QH+R H              TG   + PY C  CG+ F
Sbjct: 403 TDKKHYECGECGKSFSQKSSLIQHQRFH--------------TG---EKPYGCEECGKSF 445

Query: 583 RAMAGLRLHQRVHARAR 599
            +   LR HQRVHA  R
Sbjct: 446 SSEGHLRSHQRVHAGER 462



 Score =  110 bits (275), Expect = 4e-24
 Identities = 92/407 (22%), Positives = 155/407 (38%), Gaps = 80/407 (19%)

Query: 54  HHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPEL 100
           HHQ        + C ECG  ++    ++ HQ  H  A   E     ++ +++      + 
Sbjct: 481 HHQRVHSGERPYQCGECGKSFSQKGNLVLHQRVHTGARPYECGECGKSFSSKGHLRNHQQ 540

Query: 101 VPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRK 160
           +   +  ++CGEC +     G L+ HQ  H RE +    Y C +C + F S    + H +
Sbjct: 541 IHTGDRLYECGECGKSFSHKGTLILHQRVHPRERS----YGCGECGKSFSS----IGHLR 592

Query: 161 AQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHF 220
           + H      E                         PYEC EC    +     + HQ  H 
Sbjct: 593 S-HQRVHTGE------------------------RPYECGECGKSFSHKRSLVHHQRMHT 627

Query: 221 --------DSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWA 272
                   D  +     G     +     E   +  E  +  +  G+  +     T    
Sbjct: 628 GERPYKCGDCGKSFNEKGHLRNHQRVHTTERPFKCGECGKCFSHKGNLILHQHGHTGERP 687

Query: 273 QGCGDCPQ----------HQPSAGA-------------RRQHRRTAHSPA-SATHPFHCS 308
             C +C +          HQ                  R +++  AH    +   P+ C+
Sbjct: 688 YVCRECGKLFKKKSHLLVHQRIHNGEKPYACEACQKFFRNKYQLIAHQRVHTGERPYECN 747

Query: 309 QCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGR 367
            C +SF+ ++    H R H G   +EC+ C K F +++S  +H R+H GE  Y C +CG+
Sbjct: 748 DCGKSFTHSSTFCVHKRIHTGEKPYECSECGKSFAESSSFTKHKRVHTGEKPYECSECGK 807

Query: 368 GFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKS 413
            F    +L  H+R HT    ++C +CGK F+  +  L H+ +H  K+
Sbjct: 808 SFAESSSLTKHKRVHTGEKPYKCEKCGKLFNKKSHLLVHQSSHWRKA 854



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 16/65 (24%), Positives = 30/65 (46%)

Query: 487 VRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQH 546
           VR  +   + ++   C  CG     + +++ HQ TH   + ++C   G +   S N  QH
Sbjct: 79  VRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQH 138

Query: 547 RRLHL 551
           +  H+
Sbjct: 139 QNEHI 143



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 23/100 (23%), Positives = 37/100 (37%), Gaps = 31/100 (31%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G++ A S  F  H+        + CSECG  +     +  H+  H               
Sbjct: 778 GKSFAESSSFTKHKRVHTGEKPYECSECGKSFAESSSLTKHKRVHT-------------- 823

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRES 134
                     E P++C +C +L      LL HQ +H R++
Sbjct: 824 ---------GEKPYKCEKCGKLFNKKSHLLVHQSSHWRKA 854


>gi|52138523 zinc finger protein 418 [Homo sapiens]
          Length = 676

 Score =  219 bits (557), Expect = 8e-57
 Identities = 151/543 (27%), Positives = 212/543 (39%), Gaps = 131/543 (24%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLIL 118
           C ECG  ++  + V +HQ  H                         + P++CGEC +   
Sbjct: 232 CWECGKSFSKYDSVSNHQRVHT-----------------------GKRPYECGECGKSFS 268

Query: 119 SPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLP 178
             G L+ HQ  H      +  Y+C +C + F      V H++                  
Sbjct: 269 HKGSLVQHQRVH----TGKRPYECGECGKSFSHKGSLVQHQRVH---------------- 308

Query: 179 PPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDD 238
                            PYEC EC    +     ++HQ  H                   
Sbjct: 309 -------------TGERPYECGECGKSFSQNGTLIKHQRVH------------------- 336

Query: 239 EEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSP 298
              E   E  E  +   + G+        T+     C +C +     G   +H R     
Sbjct: 337 -TGERPYECEECGKCFTQKGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRVH--- 392

Query: 299 ASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGE 357
            +   P+ C +C +SFS    L+ H R H G   +EC  C K F +  +L QH R H GE
Sbjct: 393 -TRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGE 451

Query: 358 ARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAP 416
             Y C +C + F  +  L+ H+R HT    + C  CGK+F + + F  H+R H G+    
Sbjct: 452 RPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEK--- 508

Query: 417 PTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGV 476
                    P E               C +C KSF  +  L RHRR   G  ER + CG 
Sbjct: 509 ---------PFE---------------CSECGKSFPQSCSLLRHRRVHTG--ERPYECGE 542

Query: 477 CGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKR 536
           CGK F +   +  H +THT ERP++C  CGK F+SL     H+  HTG RPY+C +CGK 
Sbjct: 543 CGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSSLLE---HRRVHTGERPYECRECGKT 599

Query: 537 FTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHA 596
           FT+ S   +H+RLH R                   PY C  CG+ F     L  H+RVH 
Sbjct: 600 FTRRSAHFKHQRLHTRG-----------------KPYECSECGKSFAETFSLTEHRRVHT 642

Query: 597 RAR 599
             R
Sbjct: 643 GER 645



 Score =  204 bits (520), Expect = 2e-52
 Identities = 136/455 (29%), Positives = 193/455 (42%), Gaps = 88/455 (19%)

Query: 197 YECPECSTLCATPEEFLEHQGTH---------------FDSLEKEERNGLEEEEEDDEED 241
           + C  C  +        +HQGTH               +DS  +  +N    E+      
Sbjct: 82  HSCEMCGAILGDILHLADHQGTHHKQKLHRCEAWGNKLYDSSNRPHQNQYLGEKPYRSSV 141

Query: 242 EE-------DDEEMEDEEAMAEVGDDAVGGD--------------------ESTAGWAQ- 273
           EE            E+     + G D +                       ES   W   
Sbjct: 142 EEALFVKRCKFHVSEESSIFIQSGKDFLPSSGLLLQEATHTGEKSNSKPECESPFQWGDT 201

Query: 274 --GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-G 330
              CG+C +H  +     Q +R       +    +C +C +SFS  + +  H R H G  
Sbjct: 202 HYSCGECMKHSSTKHVFVQQQR-----LPSREECYCWECGKSFSKYDSVSNHQRVHTGKR 256

Query: 331 THECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC 390
            +EC  C K F    SL QH R+H G+  Y C +CG+ F  + +LV H+R HT    + C
Sbjct: 257 PYECGECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYEC 316

Query: 391 -RCGKTFSNMTKFLYHRRTHAGK---------SGAPPTGATAPPAPAEPTPPPPPPAPPA 440
             CGK+FS     + H+R H G+               G          +  P       
Sbjct: 317 GECGKSFSQNGTLIKHQRVHTGERPYECEECGKCFTQKGNLIQHQRGHTSERP------- 369

Query: 441 QLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPF 500
              C +C K F+    L+ H R VH   ER + CG CGK F +  H+RNH R HTGERP+
Sbjct: 370 -YECEECGKCFSQKGTLTEHHR-VH-TRERPYECGECGKSFSRKGHLRNHQRGHTGERPY 426

Query: 501 QCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAP 560
           +C  CGK+F+   NL +HQ +HTG RPY+C +C K F   S+L +H+R+H          
Sbjct: 427 ECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVH---------- 476

Query: 561 RLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
               TG   + PY C  CG+ F+  +G R+HQRVH
Sbjct: 477 ----TG---ERPYECNECGKSFQDSSGFRVHQRVH 504



 Score =  182 bits (463), Expect = 7e-46
 Identities = 130/489 (26%), Positives = 198/489 (40%), Gaps = 86/489 (17%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCG 111
           + C ECG  ++    ++ HQ  H      E     ++ + +   ++ + V   E P++CG
Sbjct: 258 YECGECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYECG 317

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           EC +     G L+ HQ  H  E      Y+C +C + F      + H++  H S      
Sbjct: 318 ECGKSFSQNGTLIKHQRVHTGERP----YECEECGKCFTQKGNLIQHQRG-HTSE----- 367

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKE----- 226
                                   PYEC EC    +      EH   H      E     
Sbjct: 368 -----------------------RPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECG 404

Query: 227 ---ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQP 283
               R G     +     E   E  E  ++ +  G+        T      C +C +   
Sbjct: 405 KSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGERPYECRECRKLFR 464

Query: 284 SAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFK 342
                 +H+R      +   P+ C++C +SF  ++  + H R H G    EC+ C K F 
Sbjct: 465 GKSHLIEHQRVH----TGERPYECNECGKSFQDSSGFRVHQRVHTGEKPFECSECGKSFP 520

Query: 343 KAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTK 401
           ++ SL +H R+H GE  Y C +CG+ F    +L+ H++ HTA   + CR CGK FS++  
Sbjct: 521 QSCSLLRHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSSL-- 578

Query: 402 FLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHR 461
            L HRR H G+             P E               C +C K+F   S   +H+
Sbjct: 579 -LEHRRVHTGER------------PYE---------------CRECGKTFTRRSAHFKHQ 610

Query: 462 RA-VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQL 520
           R    G P   + C  CGK F +   +  H R HTGERP++C  CGK+F   ++L RHQ 
Sbjct: 611 RLHTRGKP---YECSECGKSFAETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQR 667

Query: 521 THTGARPYQ 529
            HT   PY+
Sbjct: 668 VHTERSPYK 676



 Score =  120 bits (302), Expect = 3e-27
 Identities = 83/277 (29%), Positives = 115/277 (41%), Gaps = 59/277 (21%)

Query: 362 CVDCGRGFGTELTLVAHRRAHTANPLHRCRC--GKTF------------------SNMTK 401
           C  CG   G  L L  H+  H    LHRC     K +                  S++ +
Sbjct: 84  CEMCGAILGDILHLADHQGTHHKQKLHRCEAWGNKLYDSSNRPHQNQYLGEKPYRSSVEE 143

Query: 402 FLYHRRT------------HAGKSGAPPTGA-------TAPPAPAEPTPPPPPPAPPAQL 442
            L+ +R              +GK   P +G        T   + ++P    P        
Sbjct: 144 ALFVKRCKFHVSEESSIFIQSGKDFLPSSGLLLQEATHTGEKSNSKPECESPFQWGDTHY 203

Query: 443 PCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQC 502
            C +C K  ++     + +R    P      C  CGK F K   V NH R HTG+RP++C
Sbjct: 204 SCGECMKHSSTKHVFVQQQRL---PSREECYCWECGKSFSKYDSVSNHQRVHTGKRPYEC 260

Query: 503 HSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRL 562
             CGK+F+   +L +HQ  HTG RPY+C +CGK F+   +L QH+R+H            
Sbjct: 261 GECGKSFSHKGSLVQHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVH------------ 308

Query: 563 PITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
             TG   + PY CG CG+ F     L  HQRVH   R
Sbjct: 309 --TG---ERPYECGECGKSFSQNGTLIKHQRVHTGER 340



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 45/185 (24%), Positives = 62/185 (33%), Gaps = 39/185 (21%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G++   S  F+ HQ        F CSECG  +     +L H+  H               
Sbjct: 488 GKSFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHT-------------- 533

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++CGEC +       LL HQ  H  E      Y+C +C + F S   
Sbjct: 534 ---------GERPYECGECGKSFHQSSSLLRHQKTHTAERP----YECRECGKFFSS--- 577

Query: 155 WVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLE 214
            + HR+  H      E                      + +PYEC EC    A      E
Sbjct: 578 LLEHRRV-HTGERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTE 636

Query: 215 HQGTH 219
           H+  H
Sbjct: 637 HRRVH 641


>gi|96303826 zinc finger protein 16 [Homo sapiens]
          Length = 682

 Score =  216 bits (551), Expect = 4e-56
 Identities = 143/543 (26%), Positives = 214/543 (39%), Gaps = 128/543 (23%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + CSECG  +    +   HQ  H                        +E P+ C EC + 
Sbjct: 265 YQCSECGKAFRGHSDFSRHQSHH-----------------------SSERPYMCNECGKA 301

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
                 L  HQ +H+ E      Y+C +C + F      + H++                
Sbjct: 302 FSQNSSLKKHQKSHMSEKP----YECNECGKAFRRSSNLIQHQRIHSGE----------- 346

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE 236
                             +PY C EC          ++H  TH                 
Sbjct: 347 ------------------KPYVCSECGKAFRRSSNLIKHHRTH----------------- 371

Query: 237 DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAH 296
                E+  E  E  +A ++           T      C DC +         +H R   
Sbjct: 372 ---TGEKPFECGECGKAFSQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHRVH- 427

Query: 297 SPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHR 355
              +   P+ CS C ++FS ++ L  H R H G   H C  C K F  ++ L +H  +H 
Sbjct: 428 ---TGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGKAFSYSSVLRKHQIIHT 484

Query: 356 GEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSG 414
           GE  Y C  CG+ F     L+ H+  HT +  + C  CGKTF   +  + H+R H G+  
Sbjct: 485 GEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLILHQRVHTGEK- 543

Query: 415 APPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRC 474
                      P E               C +C K+F+ +S L +H+R  +G   + H C
Sbjct: 544 -----------PYE---------------CTECGKTFSQSSTLIQHQRIHNGL--KPHEC 575

Query: 475 GVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCG 534
             CGK F +  ++ +H + HTGE+P+ C  CGK F+  ++L +HQ+ HTG RPY+C +CG
Sbjct: 576 NQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECG 635

Query: 535 KRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRV 594
           K F+Q S L QH+R+H              TG+    PY C  CG+ F   + L  HQ +
Sbjct: 636 KAFSQRSVLIQHQRIH--------------TGV---KPYDCAACGKAFSQRSKLIKHQLI 678

Query: 595 HAR 597
           H R
Sbjct: 679 HTR 681



 Score =  215 bits (548), Expect = 9e-56
 Identities = 142/506 (28%), Positives = 206/506 (40%), Gaps = 105/506 (20%)

Query: 99  ELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAH 158
           E VP AE P  C EC +      +L+  Q  H  E++    + C DC + F    + + +
Sbjct: 200 EGVPTAESPLICNECGKTFQGNPDLIQRQIVHTGEAS----FMCDDCGKTFSQNSV-LKN 254

Query: 159 RKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGT 218
           R   H+S                             + Y+C EC        +F  HQ  
Sbjct: 255 RHRSHMSE----------------------------KAYQCSECGKAFRGHSDFSRHQSH 286

Query: 219 HFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDC 278
           H            +   ++    +     M ++                       C +C
Sbjct: 287 HSSERPYMCNECGKAFSQNSSLKKHQKSHMSEKP--------------------YECNEC 326

Query: 279 PQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTC 337
            +    +    QH+R      S   P+ CS+C ++F  ++ L  H R H G    EC  C
Sbjct: 327 GKAFRRSSNLIQHQRIH----SGEKPYVCSECGKAFRRSSNLIKHHRTHTGEKPFECGEC 382

Query: 338 SKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTF 396
            K F ++A L +H R+H GE  Y C DCG+ F     L+ H R HT    ++C  CGK F
Sbjct: 383 GKAFSQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAF 442

Query: 397 SNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASR 456
           S  +  + HRR H G+                               C  C K+F+ +S 
Sbjct: 443 SQSSSLIQHRRIHTGEKPHV---------------------------CNVCGKAFSYSSV 475

Query: 457 LSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLS 516
           L +H+    G  E+ +RC VCGK F     +  H   HTG++P+ CH CGKTF   +NL 
Sbjct: 476 LRKHQIIHTG--EKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLI 533

Query: 517 RHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCG 576
            HQ  HTG +PY+C +CGK F+QSS L QH+R+H               GL    P+ C 
Sbjct: 534 LHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIH--------------NGL---KPHECN 576

Query: 577 TCGRWFRAMAGLRLHQRVHARARTLT 602
            CG+ F   + L  HQ+VH   +  T
Sbjct: 577 QCGKAFNRSSNLIHHQKVHTGEKPYT 602



 Score =  205 bits (521), Expect = 1e-52
 Identities = 141/535 (26%), Positives = 214/535 (40%), Gaps = 121/535 (22%)

Query: 28  AEMMEMSTEVTEMTPGEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQH 79
           + M E + + +E   G+A      F  HQ        +MC+ECG  ++    +  HQ+ H
Sbjct: 258 SHMSEKAYQCSEC--GKAFRGHSDFSRHQSHHSSERPYMCNECGKAFSQNSSLKKHQKSH 315

Query: 80  MLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQ 139
           M                       +E P++C EC +       L+ HQ  H  E      
Sbjct: 316 M-----------------------SEKPYECNECGKAFRRSSNLIQHQRIHSGEK----P 348

Query: 140 YQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYEC 199
           Y C +C + F      + H +                             +    +P+EC
Sbjct: 349 YVCSECGKAFRRSSNLIKHHR-----------------------------THTGEKPFEC 379

Query: 200 PECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGD 259
            EC    +      +HQ  H                      E+  E  +  +  + V +
Sbjct: 380 GECGKAFSQSAHLRKHQRVH--------------------TGEKPYECNDCGKPFSRVSN 419

Query: 260 DAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANR 319
                   T      C DC +    + +  QHRR      +   P  C+ C ++FS ++ 
Sbjct: 420 LIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRI----HTGEKPHVCNVCGKAFSYSSV 475

Query: 320 LQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAH 378
           L+ H   H G   + C+ C K F  +++L QH  +H G+  Y C +CG+ FG    L+ H
Sbjct: 476 LRKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLILH 535

Query: 379 RRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPA 437
           +R HT    + C  CGKTFS  +  + H+R H G              P E         
Sbjct: 536 QRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLK------------PHE--------- 574

Query: 438 PPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGE 497
                 C QC K+F  +S L  H++   G  E+ + C  CGKGF +  H+  H   HTGE
Sbjct: 575 ------CNQCGKAFNRSSNLIHHQKVHTG--EKPYTCVECGKGFSQSSHLIQHQIIHTGE 626

Query: 498 RPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLR 552
           RP++C  CGK F+  + L +HQ  HTG +PY C  CGK F+Q S L +H+ +H R
Sbjct: 627 RPYKCSECGKAFSQRSVLIQHQRIHTGVKPYDCAACGKAFSQRSKLIKHQLIHTR 681



 Score =  148 bits (373), Expect = 2e-35
 Identities = 119/432 (27%), Positives = 173/432 (40%), Gaps = 62/432 (14%)

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATP---EEFLEHQGTHFDSLEKEERNGLEE 233
           +P P+P  P +  + V+  P      S  C TP   +  LE    H+   + + R   +E
Sbjct: 17  VPGPSPWTPAAQ-ARVRDAPAVTHPGSAACGTPCCSDTELEAICPHYQQPDCDTRTEDKE 75

Query: 234 --EEEDDEEDEEDDEEMEDEEA-----MAEVGDDAVGGDESTAGWAQGCGD-CPQHQPSA 285
              +ED  ED E   E+ +  A     + E+GD  +  D S   W    G   PQ     
Sbjct: 76  FLHKEDIHEDLESQAEISENYAGDVSQVPELGD--LCDDVSERDWGVPEGRRLPQSLSQE 133

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFS-SANRLQAHGRAHVGGTHECTTCSKVFKKA 344
           G                    C+     FS S N +           H      + F+ +
Sbjct: 134 GDFTPAAMGLLRGPLGEKDLDCNGFDSRFSLSPNLMACQEIPTEERPHPYDMGGQSFQHS 193

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
             L  H  +   E+  +C +CG+ F     L+  +  HT      C  CGKTFS  +   
Sbjct: 194 VDLTGHEGVPTAESPLICNECGKTFQGNPDLIQRQIVHTGEASFMCDDCGKTFSQNSVLK 253

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
              R+H  +                               C +C K+F   S  SRH+  
Sbjct: 254 NRHRSHMSEKA---------------------------YQCSECGKAFRGHSDFSRHQS- 285

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
            H   ER + C  CGK F +   ++ H ++H  E+P++C+ CGK F   +NL +HQ  H+
Sbjct: 286 -HHSSERPYMCNECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHS 344

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFR 583
           G +PY C +CGK F +SSNL +H R H              TG   + P+ CG CG+ F 
Sbjct: 345 GEKPYVCSECGKAFRRSSNLIKHHRTH--------------TG---EKPFECGECGKAFS 387

Query: 584 AMAGLRLHQRVH 595
             A LR HQRVH
Sbjct: 388 QSAHLRKHQRVH 399



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 65/323 (20%), Positives = 114/323 (35%), Gaps = 72/323 (22%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSH------QEQHMLAVSEEEALTTQNVG 95
           S   +HH+       + CS+CG  ++    ++ H      ++ H+  V  + A +  +V 
Sbjct: 418 SNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGK-AFSYSSVL 476

Query: 96  LEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELW 155
            + +++   E P++C  C +       L+ HQ  H  +      Y C +C + F      
Sbjct: 477 RKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKP----YACHECGKTFGRSSNL 532

Query: 156 VAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEH 215
           + H++                                  +PYEC EC    +     ++H
Sbjct: 533 ILHQRVH-----------------------------TGEKPYECTECGKTFSQSSTLIQH 563

Query: 216 QGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGC 275
           Q  H         NGL+  E +      +             G+      E   G++Q  
Sbjct: 564 QRIH---------NGLKPHECNQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQS- 613

Query: 276 GDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHEC 334
               QHQ      R              P+ CS+C ++FS  + L  H R H G   ++C
Sbjct: 614 SHLIQHQIIHTGER--------------PYKCSECGKAFSQRSVLIQHQRIHTGVKPYDC 659

Query: 335 TTCSKVFKKAASLEQHLRLHRGE 357
             C K F + + L +H  +H  E
Sbjct: 660 AACGKAFSQRSKLIKHQLIHTRE 682



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 29/116 (25%), Positives = 46/116 (39%), Gaps = 11/116 (9%)

Query: 495 TGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPV 554
           T ERP      G++F    +L+ H+   T   P  C +CGK F  + +L Q + +H    
Sbjct: 176 TEERPHPYDMGGQSFQHSVDLTGHEGVPTAESPLICNECGKTFQGNPDLIQRQIVHTGEA 235

Query: 555 AFA-----------RAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           +F               +       ++  Y C  CG+ FR  +    HQ  H+  R
Sbjct: 236 SFMCDDCGKTFSQNSVLKNRHRSHMSEKAYQCSECGKAFRGHSDFSRHQSHHSSER 291



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 13/104 (12%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHM----LAVSE-EEAL 89
           G+A   S    HHQ        + C ECG  ++    ++ HQ  H        SE  +A 
Sbjct: 579 GKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAF 638

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRE 133
           + ++V ++ + +     P+ C  C +      +L+ HQ  H RE
Sbjct: 639 SQRSVLIQHQRIHTGVKPYDCAACGKAFSQRSKLIKHQLIHTRE 682


>gi|38045954 zinc finger protein 16 [Homo sapiens]
          Length = 682

 Score =  216 bits (551), Expect = 4e-56
 Identities = 143/543 (26%), Positives = 214/543 (39%), Gaps = 128/543 (23%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + CSECG  +    +   HQ  H                        +E P+ C EC + 
Sbjct: 265 YQCSECGKAFRGHSDFSRHQSHH-----------------------SSERPYMCNECGKA 301

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
                 L  HQ +H+ E      Y+C +C + F      + H++                
Sbjct: 302 FSQNSSLKKHQKSHMSEKP----YECNECGKAFRRSSNLIQHQRIHSGE----------- 346

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE 236
                             +PY C EC          ++H  TH                 
Sbjct: 347 ------------------KPYVCSECGKAFRRSSNLIKHHRTH----------------- 371

Query: 237 DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAH 296
                E+  E  E  +A ++           T      C DC +         +H R   
Sbjct: 372 ---TGEKPFECGECGKAFSQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHRVH- 427

Query: 297 SPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHR 355
              +   P+ CS C ++FS ++ L  H R H G   H C  C K F  ++ L +H  +H 
Sbjct: 428 ---TGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGKAFSYSSVLRKHQIIHT 484

Query: 356 GEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSG 414
           GE  Y C  CG+ F     L+ H+  HT +  + C  CGKTF   +  + H+R H G+  
Sbjct: 485 GEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLILHQRVHTGEK- 543

Query: 415 APPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRC 474
                      P E               C +C K+F+ +S L +H+R  +G   + H C
Sbjct: 544 -----------PYE---------------CTECGKTFSQSSTLIQHQRIHNGL--KPHEC 575

Query: 475 GVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCG 534
             CGK F +  ++ +H + HTGE+P+ C  CGK F+  ++L +HQ+ HTG RPY+C +CG
Sbjct: 576 NQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECG 635

Query: 535 KRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRV 594
           K F+Q S L QH+R+H              TG+    PY C  CG+ F   + L  HQ +
Sbjct: 636 KAFSQRSVLIQHQRIH--------------TGV---KPYDCAACGKAFSQRSKLIKHQLI 678

Query: 595 HAR 597
           H R
Sbjct: 679 HTR 681



 Score =  215 bits (548), Expect = 9e-56
 Identities = 142/506 (28%), Positives = 206/506 (40%), Gaps = 105/506 (20%)

Query: 99  ELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAH 158
           E VP AE P  C EC +      +L+  Q  H  E++    + C DC + F    + + +
Sbjct: 200 EGVPTAESPLICNECGKTFQGNPDLIQRQIVHTGEAS----FMCDDCGKTFSQNSV-LKN 254

Query: 159 RKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGT 218
           R   H+S                             + Y+C EC        +F  HQ  
Sbjct: 255 RHRSHMSE----------------------------KAYQCSECGKAFRGHSDFSRHQSH 286

Query: 219 HFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDC 278
           H            +   ++    +     M ++                       C +C
Sbjct: 287 HSSERPYMCNECGKAFSQNSSLKKHQKSHMSEKP--------------------YECNEC 326

Query: 279 PQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTC 337
            +    +    QH+R      S   P+ CS+C ++F  ++ L  H R H G    EC  C
Sbjct: 327 GKAFRRSSNLIQHQRIH----SGEKPYVCSECGKAFRRSSNLIKHHRTHTGEKPFECGEC 382

Query: 338 SKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTF 396
            K F ++A L +H R+H GE  Y C DCG+ F     L+ H R HT    ++C  CGK F
Sbjct: 383 GKAFSQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAF 442

Query: 397 SNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASR 456
           S  +  + HRR H G+                               C  C K+F+ +S 
Sbjct: 443 SQSSSLIQHRRIHTGEKPHV---------------------------CNVCGKAFSYSSV 475

Query: 457 LSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLS 516
           L +H+    G  E+ +RC VCGK F     +  H   HTG++P+ CH CGKTF   +NL 
Sbjct: 476 LRKHQIIHTG--EKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLI 533

Query: 517 RHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCG 576
            HQ  HTG +PY+C +CGK F+QSS L QH+R+H               GL    P+ C 
Sbjct: 534 LHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIH--------------NGL---KPHECN 576

Query: 577 TCGRWFRAMAGLRLHQRVHARARTLT 602
            CG+ F   + L  HQ+VH   +  T
Sbjct: 577 QCGKAFNRSSNLIHHQKVHTGEKPYT 602



 Score =  205 bits (521), Expect = 1e-52
 Identities = 141/535 (26%), Positives = 214/535 (40%), Gaps = 121/535 (22%)

Query: 28  AEMMEMSTEVTEMTPGEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQH 79
           + M E + + +E   G+A      F  HQ        +MC+ECG  ++    +  HQ+ H
Sbjct: 258 SHMSEKAYQCSEC--GKAFRGHSDFSRHQSHHSSERPYMCNECGKAFSQNSSLKKHQKSH 315

Query: 80  MLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQ 139
           M                       +E P++C EC +       L+ HQ  H  E      
Sbjct: 316 M-----------------------SEKPYECNECGKAFRRSSNLIQHQRIHSGEK----P 348

Query: 140 YQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYEC 199
           Y C +C + F      + H +                             +    +P+EC
Sbjct: 349 YVCSECGKAFRRSSNLIKHHR-----------------------------THTGEKPFEC 379

Query: 200 PECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGD 259
            EC    +      +HQ  H                      E+  E  +  +  + V +
Sbjct: 380 GECGKAFSQSAHLRKHQRVH--------------------TGEKPYECNDCGKPFSRVSN 419

Query: 260 DAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANR 319
                   T      C DC +    + +  QHRR      +   P  C+ C ++FS ++ 
Sbjct: 420 LIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRI----HTGEKPHVCNVCGKAFSYSSV 475

Query: 320 LQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAH 378
           L+ H   H G   + C+ C K F  +++L QH  +H G+  Y C +CG+ FG    L+ H
Sbjct: 476 LRKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSSNLILH 535

Query: 379 RRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPA 437
           +R HT    + C  CGKTFS  +  + H+R H G              P E         
Sbjct: 536 QRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLK------------PHE--------- 574

Query: 438 PPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGE 497
                 C QC K+F  +S L  H++   G  E+ + C  CGKGF +  H+  H   HTGE
Sbjct: 575 ------CNQCGKAFNRSSNLIHHQKVHTG--EKPYTCVECGKGFSQSSHLIQHQIIHTGE 626

Query: 498 RPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLR 552
           RP++C  CGK F+  + L +HQ  HTG +PY C  CGK F+Q S L +H+ +H R
Sbjct: 627 RPYKCSECGKAFSQRSVLIQHQRIHTGVKPYDCAACGKAFSQRSKLIKHQLIHTR 681



 Score =  148 bits (373), Expect = 2e-35
 Identities = 119/432 (27%), Positives = 173/432 (40%), Gaps = 62/432 (14%)

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATP---EEFLEHQGTHFDSLEKEERNGLEE 233
           +P P+P  P +  + V+  P      S  C TP   +  LE    H+   + + R   +E
Sbjct: 17  VPGPSPWTPAAQ-ARVRDAPAVTHPGSAACGTPCCSDTELEAICPHYQQPDCDTRTEDKE 75

Query: 234 --EEEDDEEDEEDDEEMEDEEA-----MAEVGDDAVGGDESTAGWAQGCGD-CPQHQPSA 285
              +ED  ED E   E+ +  A     + E+GD  +  D S   W    G   PQ     
Sbjct: 76  FLHKEDIHEDLESQAEISENYAGDVSQVPELGD--LCDDVSERDWGVPEGRRLPQSLSQE 133

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFS-SANRLQAHGRAHVGGTHECTTCSKVFKKA 344
           G                    C+     FS S N +           H      + F+ +
Sbjct: 134 GDFTPAAMGLLRGPLGEKDLDCNGFDSRFSLSPNLMACQEIPTEERPHPYDMGGQSFQHS 193

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
             L  H  +   E+  +C +CG+ F     L+  +  HT      C  CGKTFS  +   
Sbjct: 194 VDLTGHEGVPTAESPLICNECGKTFQGNPDLIQRQIVHTGEASFMCDDCGKTFSQNSVLK 253

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
              R+H  +                               C +C K+F   S  SRH+  
Sbjct: 254 NRHRSHMSEKA---------------------------YQCSECGKAFRGHSDFSRHQS- 285

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
            H   ER + C  CGK F +   ++ H ++H  E+P++C+ CGK F   +NL +HQ  H+
Sbjct: 286 -HHSSERPYMCNECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQRIHS 344

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFR 583
           G +PY C +CGK F +SSNL +H R H              TG   + P+ CG CG+ F 
Sbjct: 345 GEKPYVCSECGKAFRRSSNLIKHHRTH--------------TG---EKPFECGECGKAFS 387

Query: 584 AMAGLRLHQRVH 595
             A LR HQRVH
Sbjct: 388 QSAHLRKHQRVH 399



 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 65/323 (20%), Positives = 114/323 (35%), Gaps = 72/323 (22%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSH------QEQHMLAVSEEEALTTQNVG 95
           S   +HH+       + CS+CG  ++    ++ H      ++ H+  V  + A +  +V 
Sbjct: 418 SNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKPHVCNVCGK-AFSYSSVL 476

Query: 96  LEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELW 155
            + +++   E P++C  C +       L+ HQ  H  +      Y C +C + F      
Sbjct: 477 RKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKP----YACHECGKTFGRSSNL 532

Query: 156 VAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEH 215
           + H++                                  +PYEC EC    +     ++H
Sbjct: 533 ILHQRVH-----------------------------TGEKPYECTECGKTFSQSSTLIQH 563

Query: 216 QGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGC 275
           Q  H         NGL+  E +      +             G+      E   G++Q  
Sbjct: 564 QRIH---------NGLKPHECNQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQS- 613

Query: 276 GDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHEC 334
               QHQ      R              P+ CS+C ++FS  + L  H R H G   ++C
Sbjct: 614 SHLIQHQIIHTGER--------------PYKCSECGKAFSQRSVLIQHQRIHTGVKPYDC 659

Query: 335 TTCSKVFKKAASLEQHLRLHRGE 357
             C K F + + L +H  +H  E
Sbjct: 660 AACGKAFSQRSKLIKHQLIHTRE 682



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 29/116 (25%), Positives = 46/116 (39%), Gaps = 11/116 (9%)

Query: 495 TGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPV 554
           T ERP      G++F    +L+ H+   T   P  C +CGK F  + +L Q + +H    
Sbjct: 176 TEERPHPYDMGGQSFQHSVDLTGHEGVPTAESPLICNECGKTFQGNPDLIQRQIVHTGEA 235

Query: 555 AFA-----------RAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           +F               +       ++  Y C  CG+ FR  +    HQ  H+  R
Sbjct: 236 SFMCDDCGKTFSQNSVLKNRHRSHMSEKAYQCSECGKAFRGHSDFSRHQSHHSSER 291



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 26/104 (25%), Positives = 44/104 (42%), Gaps = 13/104 (12%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHM----LAVSE-EEAL 89
           G+A   S    HHQ        + C ECG  ++    ++ HQ  H        SE  +A 
Sbjct: 579 GKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAF 638

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRE 133
           + ++V ++ + +     P+ C  C +      +L+ HQ  H RE
Sbjct: 639 SQRSVLIQHQRIHTGVKPYDCAACGKAFSQRSKLIKHQLIHTRE 682


>gi|188528633 zinc finger protein 79 [Homo sapiens]
          Length = 498

 Score =  214 bits (544), Expect = 3e-55
 Identities = 111/324 (34%), Positives = 162/324 (50%), Gaps = 52/324 (16%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           C +C +    + +  QH+R      +   P+ CS+C R+FS    L  H R H G   + 
Sbjct: 223 CSECGKAFSQSSSLIQHQRIH----TGEKPYKCSECGRAFSQNANLTKHQRTHTGEKPYR 278

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RC 392
           C+ C K F   ++L QH R+H GE  Y C DCG+ F     L  H+R HT    ++C  C
Sbjct: 279 CSECEKAFSDCSALVQHQRIHTGEKPYECSDCGKAFRHSANLTNHQRTHTGEKPYKCSEC 338

Query: 393 GKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFA 452
           GK FS    F+ H+R H G+                               C  C K+F+
Sbjct: 339 GKAFSYCAAFIQHQRIHTGEK---------------------------PYRCAACGKAFS 371

Query: 453 SASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASL 512
            ++ L+ H+R   G  E+ ++C  CGK F +  ++  H +THTGE+P++C+ CGK F+  
Sbjct: 372 QSANLTNHQRTHTG--EKPYKCSECGKAFSQSTNLIIHQKTHTGEKPYKCNECGKFFSES 429

Query: 513 ANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSP 572
           + L RH + HTG +PY+C +CGK F QSS+L QH+R+H              TG+    P
Sbjct: 430 SALIRHHIIHTGEKPYECNECGKAFNQSSSLSQHQRIH--------------TGV---KP 472

Query: 573 YYCGTCGRWFRAMAGLRLHQRVHA 596
           Y C  CG+ FR  +    HQR+HA
Sbjct: 473 YECSECGKAFRCSSAFVRHQRLHA 496



 Score =  208 bits (530), Expect = 1e-53
 Identities = 107/295 (36%), Positives = 156/295 (52%), Gaps = 22/295 (7%)

Query: 304 PFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLC 362
           P+ C++C ++FS  + L  H ++H G   +EC+ C K F +++SL QH R+H GE  Y C
Sbjct: 192 PYACNECGKAFSYCSSLSQHQKSHTGEKPYECSECGKAFSQSSSLIQHQRIHTGEKPYKC 251

Query: 363 VDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGA- 420
            +CGR F     L  H+R HT    +RC  C K FS+ +  + H+R H G+     +   
Sbjct: 252 SECGRAFSQNANLTKHQRTHTGEKPYRCSECEKAFSDCSALVQHQRIHTGEKPYECSDCG 311

Query: 421 TAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKG 480
            A    A  T             C +C K+F+  +   +H+R   G  E+ +RC  CGK 
Sbjct: 312 KAFRHSANLTNHQRTHTGEKPYKCSECGKAFSYCAAFIQHQRIHTG--EKPYRCAACGKA 369

Query: 481 FKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQS 540
           F +  ++ NH RTHTGE+P++C  CGK F+   NL  HQ THTG +PY+C +CGK F++S
Sbjct: 370 FSQSANLTNHQRTHTGEKPYKCSECGKAFSQSTNLIIHQKTHTGEKPYKCNECGKFFSES 429

Query: 541 SNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
           S L +H  +H              TG   + PY C  CG+ F   + L  HQR+H
Sbjct: 430 SALIRHHIIH--------------TG---EKPYECNECGKAFNQSSSLSQHQRIH 467



 Score =  152 bits (384), Expect = 1e-36
 Identities = 92/332 (27%), Positives = 133/332 (40%), Gaps = 55/332 (16%)

Query: 195 EPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAM 254
           +PYEC EC    +     ++HQ  H                      E+  +  E   A 
Sbjct: 219 KPYECSECGKAFSQSSSLIQHQRIH--------------------TGEKPYKCSECGRAF 258

Query: 255 AEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSF 314
           ++  +        T      C +C +      A  QH+R      +   P+ CS C ++F
Sbjct: 259 SQNANLTKHQRTHTGEKPYRCSECEKAFSDCSALVQHQRIH----TGEKPYECSDCGKAF 314

Query: 315 SSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTEL 373
             +  L  H R H G   ++C+ C K F   A+  QH R+H GE  Y C  CG+ F    
Sbjct: 315 RHSANLTNHQRTHTGEKPYKCSECGKAFSYCAAFIQHQRIHTGEKPYRCAACGKAFSQSA 374

Query: 374 TLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPP 432
            L  H+R HT    ++C  CGK FS  T  + H++TH G+                    
Sbjct: 375 NLTNHQRTHTGEKPYKCSECGKAFSQSTNLIIHQKTHTGEK------------------- 415

Query: 433 PPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLR 492
                      C +C K F+ +S L RH     G  E+ + C  CGK F +   +  H R
Sbjct: 416 --------PYKCNECGKFFSESSALIRHHIIHTG--EKPYECNECGKAFNQSSSLSQHQR 465

Query: 493 THTGERPFQCHSCGKTFASLANLSRHQLTHTG 524
            HTG +P++C  CGK F   +   RHQ  H G
Sbjct: 466 IHTGVKPYECSECGKAFRCSSAFVRHQRLHAG 497



 Score =  130 bits (328), Expect = 3e-30
 Identities = 107/432 (24%), Positives = 159/432 (36%), Gaps = 89/432 (20%)

Query: 69  LEEVLSHQEQHMLAVSEEEALT-TQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQ 127
           L  VLS Q++  +     +  T T++      L P    P+ C EC +       L  HQ
Sbjct: 153 LRPVLSPQQRVPVEARPRKCETHTESFKNSEILKPHRAKPYACNECGKAFSYCSSLSQHQ 212

Query: 128 DAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPS 187
            +H  E      Y+C +C + F      + H++                           
Sbjct: 213 KSHTGEKP----YECSECGKAFSQSSSLIQHQRIH------------------------- 243

Query: 188 PPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEE 247
                  +PY+C EC    +      +HQ TH    EK  R    E+   D       + 
Sbjct: 244 ----TGEKPYKCSECGRAFSQNANLTKHQRTHTG--EKPYRCSECEKAFSDCSALVQHQR 297

Query: 248 MEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHC 307
           +   E   E  D               CG   +H  +      H+RT     +   P+ C
Sbjct: 298 IHTGEKPYECSD---------------CGKAFRHSANL---TNHQRTH----TGEKPYKC 335

Query: 308 SQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCG 366
           S+C ++FS       H R H G   + C  C K F ++A+L  H R H GE  Y C +CG
Sbjct: 336 SECGKAFSYCAAFIQHQRIHTGEKPYRCAACGKAFSQSANLTNHQRTHTGEKPYKCSECG 395

Query: 367 RGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPA 425
           + F     L+ H++ HT    ++C  CGK FS  +  + H   H G+             
Sbjct: 396 KAFSQSTNLIIHQKTHTGEKPYKCNECGKFFSESSALIRHHIIHTGEK------------ 443

Query: 426 PAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLI 485
           P E               C +C K+F  +S LS+H+R   G   + + C  CGK F+   
Sbjct: 444 PYE---------------CNECGKAFNQSSSLSQHQRIHTGV--KPYECSECGKAFRCSS 486

Query: 486 HVRNHLRTHTGE 497
               H R H GE
Sbjct: 487 AFVRHQRLHAGE 498



 Score =  116 bits (291), Expect = 6e-26
 Identities = 87/382 (22%), Positives = 146/382 (38%), Gaps = 67/382 (17%)

Query: 41  TPGEALASSLFFQHHQ---FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQ 92
           T  E+  +S   + H+   + C+ECG  ++    +  HQ+ H      E     +A +  
Sbjct: 174 THTESFKNSEILKPHRAKPYACNECGKAFSYCSSLSQHQKSHTGEKPYECSECGKAFSQS 233

Query: 93  NVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSP 152
           +  ++ + +   E P++C EC +       L  HQ  H  E      Y+C +C++ F   
Sbjct: 234 SSLIQHQRIHTGEKPYKCSECGRAFSQNANLTKHQRTHTGEK----PYRCSECEKAFSDC 289

Query: 153 ELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEF 212
              V H++                                  +PYEC +C          
Sbjct: 290 SALVQHQRI-----------------------------HTGEKPYECSDCGKAFRHSANL 320

Query: 213 LEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWA 272
             HQ TH                      E+  +  E  +A +            T    
Sbjct: 321 TNHQRTH--------------------TGEKPYKCSECGKAFSYCAAFIQHQRIHTGEKP 360

Query: 273 QGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GT 331
             C  C +    +     H+RT     +   P+ CS+C ++FS +  L  H + H G   
Sbjct: 361 YRCAACGKAFSQSANLTNHQRT----HTGEKPYKCSECGKAFSQSTNLIIHQKTHTGEKP 416

Query: 332 HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC- 390
           ++C  C K F ++++L +H  +H GE  Y C +CG+ F    +L  H+R HT    + C 
Sbjct: 417 YKCNECGKFFSESSALIRHHIIHTGEKPYECNECGKAFNQSSSLSQHQRIHTGVKPYECS 476

Query: 391 RCGKTFSNMTKFLYHRRTHAGK 412
            CGK F   + F+ H+R HAG+
Sbjct: 477 ECGKAFRCSSAFVRHQRLHAGE 498



 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 65/184 (35%), Positives = 90/184 (48%), Gaps = 28/184 (15%)

Query: 413 SGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRH 472
           SG+PP  A +  +  +P    PP    +        KSF     LS  +R    P E R 
Sbjct: 115 SGSPPEQALSEASFQDPCVEMPPG--DSDHGTSDLEKSFNLRPVLSPQQRV---PVEARP 169

Query: 473 R-CGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCL 531
           R C    + FK    ++ H       +P+ C+ CGK F+  ++LS+HQ +HTG +PY+C 
Sbjct: 170 RKCETHTESFKNSEILKPHRA-----KPYACNECGKAFSYCSSLSQHQKSHTGEKPYECS 224

Query: 532 DCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLH 591
           +CGK F+QSS+L QH+R+H              TG   + PY C  CGR F   A L  H
Sbjct: 225 ECGKAFSQSSSLIQHQRIH--------------TG---EKPYKCSECGRAFSQNANLTKH 267

Query: 592 QRVH 595
           QR H
Sbjct: 268 QRTH 271


>gi|194328783 zinc finger protein 287 [Homo sapiens]
          Length = 761

 Score =  213 bits (543), Expect = 4e-55
 Identities = 137/503 (27%), Positives = 219/503 (43%), Gaps = 106/503 (21%)

Query: 99  ELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAH 158
           +++PG E P++C  C +       LL HQ  H +E +    Y+C +C + F         
Sbjct: 360 KILPG-EKPYKCNVCGKKFRKYPSLLKHQSTHAKEKS----YECEECGKEF--------- 405

Query: 159 RKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGT 218
              +H+S+ +A   +                     +PYEC +C    +       HQ  
Sbjct: 406 ---RHISSLIAHQRM-----------------HTGEKPYECHQCGKAFSQRAHLTIHQRI 445

Query: 219 HFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDC 278
           H                   E+  + D+  +D    A +    +     T      C +C
Sbjct: 446 H-----------------TGEKPYKCDDCGKDFSQRAHL---TIHQRTHTGEKPYKCLEC 485

Query: 279 PQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTC 337
            +    + +   H+R      +   P+ C++C ++FS +  L  H + H G   ++C  C
Sbjct: 486 GKTFSHSSSLINHQRVH----TGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKCNEC 541

Query: 338 SKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTF 396
            KVF ++  L +H R+H GE  Y C +CG+ F    TL+ H+  HT    + C  CGK F
Sbjct: 542 WKVFSQSTYLIRHQRIHSGEKCYKCNECGKAFAHSSTLIQHQTTHTGEKSYICNICGKAF 601

Query: 397 SNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASR 456
           S       H RTH G+                               C  C K+F+ +  
Sbjct: 602 SQSANLTQHHRTHTGEK---------------------------PYKCSVCGKAFSQSVH 634

Query: 457 LSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLS 516
           L++H+R  +G  E+  +C +CGK +++  ++  H R HTGE+P++C+ CGK F   ++L+
Sbjct: 635 LTQHQRIHNG--EKPFKCNICGKAYRQGANLTQHQRIHTGEKPYKCNECGKAFIYSSSLN 692

Query: 517 RHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCG 576
           +HQ THTG RPY+C +C K F+Q + L QH+R+H              TG   + PY C 
Sbjct: 693 QHQRTHTGERPYKCNECDKDFSQRTCLIQHQRIH--------------TG---EKPYACR 735

Query: 577 TCGRWFRAMAGLRLHQRVHARAR 599
            CG+ F     L  HQRVH  A+
Sbjct: 736 ICGKTFTQSTNLIQHQRVHTGAK 758



 Score =  183 bits (464), Expect = 5e-46
 Identities = 125/496 (25%), Positives = 187/496 (37%), Gaps = 111/496 (22%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + C+ CG  +     +L HQ  H                         E  ++C EC + 
Sbjct: 368 YKCNVCGKKFRKYPSLLKHQSTH-----------------------AKEKSYECEECGKE 404

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
                 L+AHQ  H  E      Y+C  C + F        H++                
Sbjct: 405 FRHISSLIAHQRMHTGEK----PYECHQCGKAFSQRAHLTIHQRI--------------- 445

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE 236
                             +PY+C +C    +       HQ TH                 
Sbjct: 446 --------------HTGEKPYKCDDCGKDFSQRAHLTIHQRTH----------------- 474

Query: 237 DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAH 296
                E+  + +E  +  +            T      C +C +    +    QH++   
Sbjct: 475 ---TGEKPYKCLECGKTFSHSSSLINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKI-- 529

Query: 297 SPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLRLHR 355
              +   P+ C++C + FS +  L  H R H G   ++C  C K F  +++L QH   H 
Sbjct: 530 --HTGKKPYKCNECWKVFSQSTYLIRHQRIHSGEKCYKCNECGKAFAHSSTLIQHQTTHT 587

Query: 356 GEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSG 414
           GE  Y+C  CG+ F     L  H R HT    ++C  CGK FS       H+R H G+  
Sbjct: 588 GEKSYICNICGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEK- 646

Query: 415 APPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRC 474
                                        C  C K++   + L++H+R   G  E+ ++C
Sbjct: 647 --------------------------PFKCNICGKAYRQGANLTQHQRIHTG--EKPYKC 678

Query: 475 GVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCG 534
             CGK F     +  H RTHTGERP++C+ C K F+    L +HQ  HTG +PY C  CG
Sbjct: 679 NECGKAFIYSSSLNQHQRTHTGERPYKCNECDKDFSQRTCLIQHQRIHTGEKPYACRICG 738

Query: 535 KRFTQSSNLQQHRRLH 550
           K FTQS+NL QH+R+H
Sbjct: 739 KTFTQSTNLIQHQRVH 754



 Score =  152 bits (384), Expect = 1e-36
 Identities = 84/248 (33%), Positives = 124/248 (50%), Gaps = 47/248 (18%)

Query: 350 HLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRT 408
           H ++  GE  Y C  CG+ F    +L+ H+  H     + C  CGK F +++  + H+R 
Sbjct: 358 HRKILPGEKPYKCNVCGKKFRKYPSLLKHQSTHAKEKSYECEECGKEFRHISSLIAHQRM 417

Query: 409 HAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPP 468
           H G+             P E               C QC K+F+  + L+ H+R   G  
Sbjct: 418 HTGEK------------PYE---------------CHQCGKAFSQRAHLTIHQRIHTG-- 448

Query: 469 ERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPY 528
           E+ ++C  CGK F +  H+  H RTHTGE+P++C  CGKTF+  ++L  HQ  HTG +PY
Sbjct: 449 EKPYKCDDCGKDFSQRAHLTIHQRTHTGEKPYKCLECGKTFSHSSSLINHQRVHTGEKPY 508

Query: 529 QCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGL 588
            C +CGK F+QS++L QH+++H              TG   K PY C  C + F     L
Sbjct: 509 ICNECGKTFSQSTHLLQHQKIH--------------TG---KKPYKCNECWKVFSQSTYL 551

Query: 589 RLHQRVHA 596
             HQR+H+
Sbjct: 552 IRHQRIHS 559



 Score =  115 bits (288), Expect = 1e-25
 Identities = 98/427 (22%), Positives = 153/427 (35%), Gaps = 75/427 (17%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHM-----------LAVSEEEALTTQNVGLEPELVPGAE 105
           + C ECG  +  +  +++HQ  H             A S+   LT        + +   E
Sbjct: 396 YECEECGKEFRHISSLIAHQRMHTGEKPYECHQCGKAFSQRAHLTIH------QRIHTGE 449

Query: 106 GPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLS 165
            P++C +C +       L  HQ  H  E      Y+C +C + F      + H++     
Sbjct: 450 KPYKCDDCGKDFSQRAHLTIHQRTHTGEK----PYKCLECGKTFSHSSSLINHQRVHTGE 505

Query: 166 ATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEK 225
                          T L         K +PY+C EC  + +     + HQ  H      
Sbjct: 506 KPYICNECGKTFSQSTHLLQHQKIHTGK-KPYKCNECWKVFSQSTYLIRHQRIH------ 558

Query: 226 EERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSA 285
                           E+  +  E  +A A            T   +  C  C +    +
Sbjct: 559 --------------SGEKCYKCNECGKAFAHSSTLIQHQTTHTGEKSYICNICGKAFSQS 604

Query: 286 GARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKA 344
               QH RT     +   P+ CS C ++FS +  L  H R H G    +C  C K +++ 
Sbjct: 605 ANLTQHHRT----HTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNICGKAYRQG 660

Query: 345 ASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFL 403
           A+L QH R+H GE  Y C +CG+ F    +L  H+R HT    ++C  C K FS  T  +
Sbjct: 661 ANLTQHQRIHTGEKPYKCNECGKAFIYSSSLNQHQRTHTGERPYKCNECDKDFSQRTCLI 720

Query: 404 YHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
            H+R H G+                               C  C K+F  ++ L +H+R 
Sbjct: 721 QHQRIHTGEK---------------------------PYACRICGKTFTQSTNLIQHQRV 753

Query: 464 VHGPPER 470
             G   R
Sbjct: 754 HTGAKHR 760



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 28/126 (22%), Positives = 43/126 (34%), Gaps = 35/126 (27%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A + S+    HQ        F C+ CG  Y     +  HQ  H               
Sbjct: 626 GKAFSQSVHLTQHQRIHNGEKPFKCNICGKAYRQGANLTQHQRIHT-------------- 671

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++C EC +  +    L  HQ  H  E      Y+C +C + F     
Sbjct: 672 ---------GEKPYKCNECGKAFIYSSSLNQHQRTHTGER----PYKCNECDKDFSQRTC 718

Query: 155 WVAHRK 160
            + H++
Sbjct: 719 LIQHQR 724



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 13/34 (38%), Positives = 18/34 (52%)

Query: 567 LYNKSPYYCGTCGRWFRAMAGLRLHQRVHARART 600
           L  + PY C  CG+ FR    L  HQ  HA+ ++
Sbjct: 362 LPGEKPYKCNVCGKKFRKYPSLLKHQSTHAKEKS 395


>gi|37574603 zinc finger protein 256 [Homo sapiens]
          Length = 627

 Score =  212 bits (539), Expect = 1e-54
 Identities = 142/545 (26%), Positives = 216/545 (39%), Gaps = 156/545 (28%)

Query: 53  QHHQFMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGE 112
           +   +MCSECG  ++T   +  H   H                        +E P+ CGE
Sbjct: 235 RERSYMCSECGKSFSTSCSLSDHLRVHT-----------------------SEKPYTCGE 271

Query: 113 CSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPP 172
           C +       L+ H+  H         +QC +C +LF      + H++            
Sbjct: 272 CGKSYRQSSSLITHRRIH----TGVRPHQCDECGKLFNRKYDLLIHQRVH---------- 317

Query: 173 VPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLE 232
                                  PY+C EC    +     + HQ  H          G+ 
Sbjct: 318 -------------------TGERPYKCSECGKSFSHSSSLITHQRIH---------TGMR 349

Query: 233 EEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHR 292
             E                                       C +C +    + +   H+
Sbjct: 350 PYE---------------------------------------CSECGKSFIHSSSLITHQ 370

Query: 293 RTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHL 351
           R      + T P+ CS+C +SFS +  L  H R H+G G +EC+ C K+F   +   QH 
Sbjct: 371 RVH----TGTRPYMCSECGKSFSQSCHLIKHRRLHIGEGPYECSECGKLFTYRSRFFQHQ 426

Query: 352 RLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHA 410
           R+H G   + C +CG+ F  +  L+ H R HT    + C  CGK+F+  +  + H + H 
Sbjct: 427 RVHTGVRSHECHECGKLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSYLISHWKVHT 486

Query: 411 GKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPER 470
           G                         A P +  C +C KSF  +S L +H+R   G  ER
Sbjct: 487 G-------------------------ARPYE--CGECGKSFTHSSTLLQHQRVHTG--ER 517

Query: 471 RHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQC 530
            + C  CGK F +   +  H R+HTGERP++C  C K+F++ ++L +H+  HTG RPY+C
Sbjct: 518 PYECNECGKFFSQSSSLIRHRRSHTGERPYECSECWKSFSNHSSLVKHRRVHTGERPYEC 577

Query: 531 LDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRL 590
            +CGK F+QSSNL  H+R+H                   + PY C  CG++F   + L  
Sbjct: 578 SECGKSFSQSSNLTNHQRIH-----------------SGERPYECSDCGKFFTFNSNLLK 620

Query: 591 HQRVH 595
           HQ VH
Sbjct: 621 HQNVH 625



 Score =  194 bits (493), Expect = 2e-49
 Identities = 106/299 (35%), Positives = 150/299 (50%), Gaps = 22/299 (7%)

Query: 304 PFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLRLHRGEARYLC 362
           P+ CS+C +SFS ++ L  H R H G   +EC+ C K F  ++SL  H R+H G   Y+C
Sbjct: 322 PYKCSECGKSFSHSSSLITHQRIHTGMRPYECSECGKSFIHSSSLITHQRVHTGTRPYMC 381

Query: 363 VDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAG-KSGAPPTGA 420
            +CG+ F     L+ HRR H     + C  CGK F+  ++F  H+R H G +S       
Sbjct: 382 SECGKSFSQSCHLIKHRRLHIGEGPYECSECGKLFTYRSRFFQHQRVHTGVRSHECHECG 441

Query: 421 TAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKG 480
                  +               C +C KSF   S L  H +   G   R + CG CGK 
Sbjct: 442 KLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSYLISHWKVHTGA--RPYECGECGKS 499

Query: 481 FKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQS 540
           F     +  H R HTGERP++C+ CGK F+  ++L RH+ +HTG RPY+C +C K F+  
Sbjct: 500 FTHSSTLLQHQRVHTGERPYECNECGKFFSQSSSLIRHRRSHTGERPYECSECWKSFSNH 559

Query: 541 SNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           S+L +HRR+H              TG   + PY C  CG+ F   + L  HQR+H+  R
Sbjct: 560 SSLVKHRRVH--------------TG---ERPYECSECGKSFSQSSNLTNHQRIHSGER 601



 Score =  183 bits (464), Expect = 5e-46
 Identities = 108/327 (33%), Positives = 149/327 (45%), Gaps = 52/327 (15%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHE 333
           C +C +   ++ +   H R   S      P+ C +C +S+  ++ L  H R H G   H+
Sbjct: 241 CSECGKSFSTSCSLSDHLRVHTSEK----PYTCGECGKSYRQSSSLITHRRIHTGVRPHQ 296

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RC 392
           C  C K+F +   L  H R+H GE  Y C +CG+ F    +L+ H+R HT    + C  C
Sbjct: 297 CDECGKLFNRKYDLLIHQRVHTGERPYKCSECGKSFSHSSSLITHQRIHTGMRPYECSEC 356

Query: 393 GKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFA 452
           GK+F + +  + H+R H G         T P                    C +C KSF+
Sbjct: 357 GKSFIHSSSLITHQRVHTG---------TRP------------------YMCSECGKSFS 389

Query: 453 SASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASL 512
            +  L +HRR   G  E  + C  CGK F        H R HTG R  +CH CGK F+  
Sbjct: 390 QSCHLIKHRRLHIG--EGPYECSECGKLFTYRSRFFQHQRVHTGVRSHECHECGKLFSRK 447

Query: 513 ANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSP 572
            +L  H+  HTG RPY+C +CGK FT  S L  H ++H              TG     P
Sbjct: 448 FDLIVHERVHTGERPYECSECGKSFTCKSYLISHWKVH--------------TGA---RP 490

Query: 573 YYCGTCGRWFRAMAGLRLHQRVHARAR 599
           Y CG CG+ F   + L  HQRVH   R
Sbjct: 491 YECGECGKSFTHSSTLLQHQRVHTGER 517



 Score =  132 bits (333), Expect = 8e-31
 Identities = 90/309 (29%), Positives = 128/309 (41%), Gaps = 53/309 (17%)

Query: 304 PFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCV 363
           PF C +  + F   +R      AH              KK+   +  +  H  +  Y   
Sbjct: 167 PFTCKEVGKDFLVRSRFLQQQAAHTR------------KKSNRTKSAVAFHSVKNHYNWG 214

Query: 364 DCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATA 422
           +C + F  +   V H+        + C  CGK+FS       H R H  +   P T    
Sbjct: 215 ECVKAFSYKHVRVQHQGDLIRERSYMCSECGKSFSTSCSLSDHLRVHTSEK--PYT---- 268

Query: 423 PPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFK 482
                                C +C KS+  +S L  HRR   G   R H+C  CGK F 
Sbjct: 269 ---------------------CGECGKSYRQSSSLITHRRIHTGV--RPHQCDECGKLFN 305

Query: 483 KLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSN 542
           +   +  H R HTGERP++C  CGK+F+  ++L  HQ  HTG RPY+C +CGK F  SS+
Sbjct: 306 RKYDLLIHQRVHTGERPYKCSECGKSFSHSSSLITHQRIHTGMRPYECSECGKSFIHSSS 365

Query: 543 LQQHRRLH--LRPVAFARAPRLPITGLY---------NKSPYYCGTCGRWFRAMAGLRLH 591
           L  H+R+H   RP   +   +      +          + PY C  CG+ F   +    H
Sbjct: 366 LITHQRVHTGTRPYMCSECGKSFSQSCHLIKHRRLHIGEGPYECSECGKLFTYRSRFFQH 425

Query: 592 QRVHARART 600
           QRVH   R+
Sbjct: 426 QRVHTGVRS 434



 Score =  122 bits (306), Expect = 1e-27
 Identities = 102/421 (24%), Positives = 149/421 (35%), Gaps = 103/421 (24%)

Query: 59  CSECGSLYNTLEEVLSHQEQHM-----------LAVSEEEALTTQNVGLEPELVPGAEGP 107
           C ECG L+N   ++L HQ  H             + S   +L T       + +     P
Sbjct: 297 CDECGKLFNRKYDLLIHQRVHTGERPYKCSECGKSFSHSSSLITH------QRIHTGMRP 350

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           ++C EC +  +    L+ HQ  H         Y C +C + F      + HR+       
Sbjct: 351 YECSECGKSFIHSSSLITHQRVH----TGTRPYMCSECGKSFSQSCHLIKHRRLH----- 401

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
                                   +   PYEC EC  L      F +HQ  H        
Sbjct: 402 ------------------------IGEGPYECSECGKLFTYRSRFFQHQRVH-------- 429

Query: 228 RNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGA 287
             G+   E             E  +  +   D  V     T      C +C +       
Sbjct: 430 -TGVRSHECH-----------ECGKLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSY 477

Query: 288 RRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAAS 346
              H +  H+ A    P+ C +C +SF+ ++ L  H R H G   +EC  C K F +++S
Sbjct: 478 LISHWK-VHTGA---RPYECGECGKSFTHSSTLLQHQRVHTGERPYECNECGKFFSQSSS 533

Query: 347 LEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYH 405
           L +H R H GE  Y C +C + F    +LV HRR HT    + C  CGK+FS  +    H
Sbjct: 534 LIRHRRSHTGERPYECSECWKSFSNHSSLVKHRRVHTGERPYECSECGKSFSQSSNLTNH 593

Query: 406 RRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVH 465
           +R H+G+             P E               C  C K F   S L +H+    
Sbjct: 594 QRIHSGE------------RPYE---------------CSDCGKFFTFNSNLLKHQNVHK 626

Query: 466 G 466
           G
Sbjct: 627 G 627



 Score =  112 bits (281), Expect = 8e-25
 Identities = 89/337 (26%), Positives = 130/337 (38%), Gaps = 43/337 (12%)

Query: 267 STAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRA 326
           S  G   G  + P  Q ++  R    R   +  S      C  C         L  H   
Sbjct: 52  SLGGSGAGDEEAPYQQSTSPQRVSQVRIPKALPSPQKTNPCEICGPVLRQILHLVEHQGT 111

Query: 327 HVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTAN 385
           H G   +    C K  +  A L QH + H G+  +         G ++ L +     +  
Sbjct: 112 HHGQKLYTDGACRKQLQFTAYLHQHQKQHVGQKHFRS-----NGGRDMFLSSCTFEVSGK 166

Query: 386 PLHRCRCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCP 445
           P      GK F   ++FL  +  H  K       A A  +                    
Sbjct: 167 PFTCKEVGKDFLVRSRFLQQQAAHTRKKSNRTKSAVAFHSVKN------------HYNWG 214

Query: 446 QCSKSFASASRLSRHRRAVHGPP---ERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQC 502
           +C K+F+      +H R  H      ER + C  CGK F     + +HLR HT E+P+ C
Sbjct: 215 ECVKAFSY-----KHVRVQHQGDLIRERSYMCSECGKSFSTSCSLSDHLRVHTSEKPYTC 269

Query: 503 HSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRL 562
             CGK++   ++L  H+  HTG RP+QC +CGK F +  +L  H+R+H            
Sbjct: 270 GECGKSYRQSSSLITHRRIHTGVRPHQCDECGKLFNRKYDLLIHQRVH------------ 317

Query: 563 PITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
             TG   + PY C  CG+ F   + L  HQR+H   R
Sbjct: 318 --TG---ERPYKCSECGKSFSHSSSLITHQRIHTGMR 349



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 51/219 (23%), Positives = 76/219 (34%), Gaps = 34/219 (15%)

Query: 410 AGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPE 469
           AG   AP   +T+P   ++   P   P+P    PC  C         L  H+   HG  +
Sbjct: 58  AGDEEAPYQQSTSPQRVSQVRIPKALPSPQKTNPCEICGPVLRQILHLVEHQGTHHG--Q 115

Query: 470 RRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQ 529
           + +  G C K  +   ++  H + H G++ F+ +     F S              +P+ 
Sbjct: 116 KLYTDGACRKQLQFTAYLHQHQKQHVGQKHFRSNGGRDMFLSSCTFE------VSGKPFT 169

Query: 530 CLDCGKRFTQSSNLQQHRRLHLRP--------VAFARAP-----------------RLPI 564
           C + GK F   S   Q +  H R         VAF                     R+  
Sbjct: 170 CKEVGKDFLVRSRFLQQQAAHTRKKSNRTKSAVAFHSVKNHYNWGECVKAFSYKHVRVQH 229

Query: 565 TG-LYNKSPYYCGTCGRWFRAMAGLRLHQRVHARARTLT 602
            G L  +  Y C  CG+ F     L  H RVH   +  T
Sbjct: 230 QGDLIRERSYMCSECGKSFSTSCSLSDHLRVHTSEKPYT 268



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 41/183 (22%), Positives = 65/183 (35%), Gaps = 45/183 (24%)

Query: 49  SLFFQHHQFM-------CSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGL 96
           S FFQH +         C ECG L++   +++ H+  H      E     ++ T ++  +
Sbjct: 420 SRFFQHQRVHTGVRSHECHECGKLFSRKFDLIVHERVHTGERPYECSECGKSFTCKSYLI 479

Query: 97  EPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWV 156
               V     P++CGEC +       LL HQ  H  E      Y+C +C + F      +
Sbjct: 480 SHWKVHTGARPYECGECGKSFTHSSTLLQHQRVHTGERP----YECNECGKFFSQSSSLI 535

Query: 157 AHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQ 216
            HR+                             S     PYEC EC    +     ++H+
Sbjct: 536 RHRR-----------------------------SHTGERPYECSECWKSFSNHSSLVKHR 566

Query: 217 GTH 219
             H
Sbjct: 567 RVH 569



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 16/114 (14%)

Query: 48  SSLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVG 95
           SS   QH +       + C+ECG  ++    ++ H+  H      E     ++ +  +  
Sbjct: 503 SSTLLQHQRVHTGERPYECNECGKFFSQSSSLIRHRRSHTGERPYECSECWKSFSNHSSL 562

Query: 96  LEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
           ++   V   E P++C EC +       L  HQ  H    + +  Y+C DC + F
Sbjct: 563 VKHRRVHTGERPYECSECGKSFSQSSNLTNHQRIH----SGERPYECSDCGKFF 612


>gi|20304115 zinc finger protein 551 [Homo sapiens]
          Length = 654

 Score =  211 bits (538), Expect = 1e-54
 Identities = 143/506 (28%), Positives = 212/506 (41%), Gaps = 97/506 (19%)

Query: 106 GPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLS 165
           G ++C +C +       L+ HQ  H      Q  ++C +C+E F      + H K  H  
Sbjct: 233 GLYECSKCEKAFTCKNTLVQHQQIH----TGQKMFECSECEESFSKKCHLILH-KIIHTG 287

Query: 166 ATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEK 225
                                         PYEC +         EF+ HQ  H   +  
Sbjct: 288 E----------------------------RPYECSDREKAFIHKSEFIHHQRRHTGGVRH 319

Query: 226 EERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG----------C 275
           E   G   +    + +  + + +   E   E G+      +S++ +             C
Sbjct: 320 E--CGECRKTFSYKSNLIEHQRVHTGERPYECGECGKSFRQSSSLFRHQRVHSGERPYQC 377

Query: 276 GDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HEC 334
            +C +         +HRR      +   P+ CS C +SFS  + L  H R H G   +EC
Sbjct: 378 CECGKSFRQIFNLIRHRRVH----TGEMPYQCSDCGKSFSCKSELIQHQRIHSGERPYEC 433

Query: 335 TTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCG 393
             C K F++ ++L +H  +H G+  Y C +C + F  +  L+ H+R HT    + C  CG
Sbjct: 434 RECGKSFRQFSNLIRHRSIHTGDRPYECSECEKSFSRKFILIQHQRVHTGERPYECSECG 493

Query: 394 KTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFAS 453
           K+F+  +  + HRR H G         T P                    C +C KSF  
Sbjct: 494 KSFTRKSDLIQHRRIHTG---------TRP------------------YECSECGKSFRQ 526

Query: 454 ASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLA 513
            S L +HRR   G  ER + C  CGK F +   +  H R HTGERP++C  CGK+F+  +
Sbjct: 527 RSGLIQHRRLHTG--ERPYECSECGKSFSQSASLIQHQRVHTGERPYECSECGKSFSQSS 584

Query: 514 NLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPY 573
           +L +HQ  HTG RPY+C  CGK FT  S+L QH+R+H              TG   + PY
Sbjct: 585 SLIQHQRGHTGERPYECSQCGKPFTHKSDLIQHQRVH--------------TG---ERPY 627

Query: 574 YCGTCGRWFRAMAGLRLHQRVHARAR 599
            C  CG+ F   + L  H+RVH   R
Sbjct: 628 ECSECGKSFSRKSNLIRHRRVHTEER 653



 Score =  211 bits (537), Expect = 2e-54
 Identities = 135/501 (26%), Positives = 209/501 (41%), Gaps = 93/501 (18%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQH----MLAVSE-EEALTTQNVGLEPELVPGAEGPFQCG 111
           + CS+C   +     ++ HQ+ H    M   SE EE+ + +   +  +++   E P++C 
Sbjct: 235 YECSKCEKAFTCKNTLVQHQQIHTGQKMFECSECEESFSKKCHLILHKIIHTGERPYECS 294

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           +  +  +   E + HQ  H       ++++C +C++ F      + H++           
Sbjct: 295 DREKAFIHKSEFIHHQRRH----TGGVRHECGECRKTFSYKSNLIEHQRV---------- 340

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGL 231
                                   PYEC EC            HQ  H            
Sbjct: 341 -------------------HTGERPYECGECGKSFRQSSSLFRHQRVH------------ 369

Query: 232 EEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQH 291
                     E   +  E  ++  ++ +        T      C DC +         QH
Sbjct: 370 --------SGERPYQCCECGKSFRQIFNLIRHRRVHTGEMPYQCSDCGKSFSCKSELIQH 421

Query: 292 RRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGG-THECTTCSKVFKKAASLEQH 350
           +R      S   P+ C +C +SF   + L  H   H G   +EC+ C K F +   L QH
Sbjct: 422 QRI----HSGERPYECRECGKSFRQFSNLIRHRSIHTGDRPYECSECEKSFSRKFILIQH 477

Query: 351 LRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTH 409
            R+H GE  Y C +CG+ F  +  L+ HRR HT    + C  CGK+F   +  + HRR H
Sbjct: 478 QRVHTGERPYECSECGKSFTRKSDLIQHRRIHTGTRPYECSECGKSFRQRSGLIQHRRLH 537

Query: 410 AGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPE 469
            G+             P E               C +C KSF+ ++ L +H+R   G  E
Sbjct: 538 TGE------------RPYE---------------CSECGKSFSQSASLIQHQRVHTG--E 568

Query: 470 RRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQ 529
           R + C  CGK F +   +  H R HTGERP++C  CGK F   ++L +HQ  HTG RPY+
Sbjct: 569 RPYECSECGKSFSQSSSLIQHQRGHTGERPYECSQCGKPFTHKSDLIQHQRVHTGERPYE 628

Query: 530 CLDCGKRFTQSSNLQQHRRLH 550
           C +CGK F++ SNL +HRR+H
Sbjct: 629 CSECGKSFSRKSNLIRHRRVH 649



 Score =  178 bits (451), Expect = 2e-44
 Identities = 126/478 (26%), Positives = 183/478 (38%), Gaps = 121/478 (25%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCG 111
           + CS+    +    E + HQ +H   V  E     +  + ++  +E + V   E P++CG
Sbjct: 291 YECSDREKAFIHKSEFIHHQRRHTGGVRHECGECRKTFSYKSNLIEHQRVHTGERPYECG 350

Query: 112 ECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP 171
           EC +       L  HQ  H  E      YQC +C + F      + HR+           
Sbjct: 351 ECGKSFRQSSSLFRHQRVHSGERP----YQCCECGKSFRQIFNLIRHRRVH--------- 397

Query: 172 PVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGL 231
                                   PY+C +C    +   E ++HQ  H      E     
Sbjct: 398 --------------------TGEMPYQCSDCGKSFSCKSELIQHQRIHSGERPYE----- 432

Query: 232 EEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQH 291
                                                      C +C +         +H
Sbjct: 433 -------------------------------------------CRECGKSFRQFSNLIRH 449

Query: 292 RRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQH 350
           R    S  +   P+ CS+C++SFS    L  H R H G   +EC+ C K F + + L QH
Sbjct: 450 R----SIHTGDRPYECSECEKSFSRKFILIQHQRVHTGERPYECSECGKSFTRKSDLIQH 505

Query: 351 LRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTH 409
            R+H G   Y C +CG+ F     L+ HRR HT    + C  CGK+FS     + H+R H
Sbjct: 506 RRIHTGTRPYECSECGKSFRQRSGLIQHRRLHTGERPYECSECGKSFSQSASLIQHQRVH 565

Query: 410 AGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPE 469
            G+             P E               C +C KSF+ +S L +H+R   G  E
Sbjct: 566 TGER------------PYE---------------CSECGKSFSQSSSLIQHQRGHTG--E 596

Query: 470 RRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARP 527
           R + C  CGK F     +  H R HTGERP++C  CGK+F+  +NL RH+  HT  RP
Sbjct: 597 RPYECSQCGKPFTHKSDLIQHQRVHTGERPYECSECGKSFSRKSNLIRHRRVHTEERP 654



 Score =  170 bits (430), Expect = 4e-42
 Identities = 100/328 (30%), Positives = 151/328 (46%), Gaps = 51/328 (15%)

Query: 277 DCPQHQPSAGARRQHRRTA-HSPA--SATHPFHCSQCQRSFSSANRLQAHGRA-HVGGTH 332
           D  QH+ +      H  ++ H  A  +A   +   + +++ S  + L  H      GG +
Sbjct: 176 DLLQHEATPSGEEPHSSSSKHIQAFFNAKSYYKWGEYRKASSHKHTLVQHQSVCSEGGLY 235

Query: 333 ECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR- 391
           EC+ C K F    +L QH ++H G+  + C +C   F  +  L+ H+  HT    + C  
Sbjct: 236 ECSKCEKAFTCKNTLVQHQQIHTGQKMFECSECEESFSKKCHLILHKIIHTGERPYECSD 295

Query: 392 CGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSF 451
             K F + ++F++H+R H G                             +  C +C K+F
Sbjct: 296 REKAFIHKSEFIHHQRRHTG---------------------------GVRHECGECRKTF 328

Query: 452 ASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFAS 511
           +  S L  H+R   G  ER + CG CGK F++   +  H R H+GERP+QC  CGK+F  
Sbjct: 329 SYKSNLIEHQRVHTG--ERPYECGECGKSFRQSSSLFRHQRVHSGERPYQCCECGKSFRQ 386

Query: 512 LANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKS 571
           + NL RH+  HTG  PYQC DCGK F+  S L QH+R+H                   + 
Sbjct: 387 IFNLIRHRRVHTGEMPYQCSDCGKSFSCKSELIQHQRIH-----------------SGER 429

Query: 572 PYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           PY C  CG+ FR  + L  H+ +H   R
Sbjct: 430 PYECRECGKSFRQFSNLIRHRSIHTGDR 457



 Score =  119 bits (298), Expect = 9e-27
 Identities = 85/376 (22%), Positives = 139/376 (36%), Gaps = 99/376 (26%)

Query: 48  SSLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPEL 100
           SS  F+H +       + C ECG  +  +  ++ H+  H   +  + +   ++   + EL
Sbjct: 359 SSSLFRHQRVHSGERPYQCCECGKSFRQIFNLIRHRRVHTGEMPYQCSDCGKSFSCKSEL 418

Query: 101 VP-----GAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELW 155
           +        E P++C EC +       L+ H+  H  +      Y+C +C++ F    + 
Sbjct: 419 IQHQRIHSGERPYECRECGKSFRQFSNLIRHRSIHTGDR----PYECSECEKSFSRKFIL 474

Query: 156 VAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEH 215
           + H++                                   PYEC EC        + ++H
Sbjct: 475 IQHQRV-----------------------------HTGERPYECSECGKSFTRKSDLIQH 505

Query: 216 QGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGC 275
           +  H  +   E                                                C
Sbjct: 506 RRIHTGTRPYE------------------------------------------------C 517

Query: 276 GDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHEC 334
            +C +         QHRR      +   P+ CS+C +SFS +  L  H R H G   +EC
Sbjct: 518 SECGKSFRQRSGLIQHRRL----HTGERPYECSECGKSFSQSASLIQHQRVHTGERPYEC 573

Query: 335 TTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCG 393
           + C K F +++SL QH R H GE  Y C  CG+ F  +  L+ H+R HT    + C  CG
Sbjct: 574 SECGKSFSQSSSLIQHQRGHTGERPYECSQCGKPFTHKSDLIQHQRVHTGERPYECSECG 633

Query: 394 KTFSNMTKFLYHRRTH 409
           K+FS  +  + HRR H
Sbjct: 634 KSFSRKSNLIRHRRVH 649



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 13/104 (12%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EAL 89
           G++ + S     HQ        + CSECG  ++    ++ HQ  H      E     +  
Sbjct: 549 GKSFSQSASLIQHQRVHTGERPYECSECGKSFSQSSSLIQHQRGHTGERPYECSQCGKPF 608

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRE 133
           T ++  ++ + V   E P++C EC +       L+ H+  H  E
Sbjct: 609 THKSDLIQHQRVHTGERPYECSECGKSFSRKSNLIRHRRVHTEE 652



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 33/140 (23%), Positives = 48/140 (34%), Gaps = 34/140 (24%)

Query: 477 CGKGFKKLIHVRNHLRTHTGERPFQCHS-----------------CGKTFASLANLSRHQ 519
           CG+ F     +  H  T +GE P    S                   K  +    L +HQ
Sbjct: 167 CGEAFPAPTDLLQHEATPSGEEPHSSSSKHIQAFFNAKSYYKWGEYRKASSHKHTLVQHQ 226

Query: 520 LTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCG 579
              +    Y+C  C K FT  + L QH+++H              TG   +  + C  C 
Sbjct: 227 SVCSEGGLYECSKCEKAFTCKNTLVQHQQIH--------------TG---QKMFECSECE 269

Query: 580 RWFRAMAGLRLHQRVHARAR 599
             F     L LH+ +H   R
Sbjct: 270 ESFSKKCHLILHKIIHTGER 289


>gi|190570172 zinc finger protein 180 [Homo sapiens]
          Length = 692

 Score =  210 bits (535), Expect = 3e-54
 Identities = 119/330 (36%), Positives = 163/330 (49%), Gaps = 52/330 (15%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           C +C +    +     H+RT     +   P+ C+QC +SFS +  L  H R H G   +E
Sbjct: 383 CSECGKSFSRSSHLVSHQRTH----TGEKPYRCNQCGKSFSQSYVLVVHQRTHTGEKPYE 438

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RC 392
           C  C K F+++  L  H R H GE  Y C  CG+ F     L+AH+R HT    + C +C
Sbjct: 439 CNQCGKSFRQSYKLIAHQRTHTGEKPYECNQCGKSFIQSYKLIAHQRIHTGEKPYECNQC 498

Query: 393 GKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFA 452
           GK+FS   K + H+RTH G+             P E               C QC KSF+
Sbjct: 499 GKSFSQSYKLVAHQRTHTGEK------------PFE---------------CNQCGKSFS 531

Query: 453 SASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASL 512
            +S+L  H+R   G  E+ + C  CGK F +  H+  H R HTGE+P++C+ CGK+F+  
Sbjct: 532 WSSQLVAHQRTHTG--EKPYECSECGKSFNRSSHLVMHQRIHTGEKPYECNQCGKSFSQS 589

Query: 513 ANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSP 572
             L  HQ THTG +PY+C  CGK F QSS L QH+R H              TG   + P
Sbjct: 590 YVLVVHQRTHTGEKPYECSQCGKSFRQSSCLTQHQRTH--------------TG---EKP 632

Query: 573 YYCGTCGRWFRAMAGLRLHQRVHARARTLT 602
           + C  CG+ F   A L +HQR H   +  T
Sbjct: 633 FECNQCGKTFSLSARLIVHQRTHTGEKPFT 662



 Score =  186 bits (473), Expect = 5e-47
 Identities = 127/456 (27%), Positives = 190/456 (41%), Gaps = 92/456 (20%)

Query: 97  EPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWV 156
           E + +P  E  ++C E S          +    ++R ++ +  ++C  C + F      V
Sbjct: 318 EQQRIPFEESQYKCSETSHS--------SSLTQNMRNNSEEKPFECNQCGKSFSWSSHLV 369

Query: 157 AHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQ 216
           AH++                             +    +PYEC EC    +     + HQ
Sbjct: 370 AHQR-----------------------------THTGEKPYECSECGKSFSRSSHLVSHQ 400

Query: 217 GTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCG 276
            TH    EK  R                    +  ++ ++     V     T      C 
Sbjct: 401 RTHTG--EKPYRCN------------------QCGKSFSQSYVLVVHQRTHTGEKPYECN 440

Query: 277 DCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECT 335
            C +    +     H+RT     +   P+ C+QC +SF  + +L AH R H G   +EC 
Sbjct: 441 QCGKSFRQSYKLIAHQRTH----TGEKPYECNQCGKSFIQSYKLIAHQRIHTGEKPYECN 496

Query: 336 TCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGK 394
            C K F ++  L  H R H GE  + C  CG+ F     LVAH+R HT    + C  CGK
Sbjct: 497 QCGKSFSQSYKLVAHQRTHTGEKPFECNQCGKSFSWSSQLVAHQRTHTGEKPYECSECGK 556

Query: 395 TFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASA 454
           +F+  +  + H+R H G+             P E               C QC KSF+ +
Sbjct: 557 SFNRSSHLVMHQRIHTGEK------------PYE---------------CNQCGKSFSQS 589

Query: 455 SRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLAN 514
             L  H+R   G  E+ + C  CGK F++   +  H RTHTGE+PF+C+ CGKTF+  A 
Sbjct: 590 YVLVVHQRTHTG--EKPYECSQCGKSFRQSSCLTQHQRTHTGEKPFECNQCGKTFSLSAR 647

Query: 515 LSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLH 550
           L  HQ THTG +P+ C+ CGK F  S  L +H+  H
Sbjct: 648 LIVHQRTHTGEKPFTCIQCGKAFINSYKLIRHQATH 683



 Score =  177 bits (450), Expect = 2e-44
 Identities = 135/485 (27%), Positives = 192/485 (39%), Gaps = 105/485 (21%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEE---------ALTTQNVGLEPELVPGAEGP 107
           F   ECG + N     +SH EQ  +   E +         +  TQN+    E     E P
Sbjct: 301 FDFKECGQVLNPK---ISHNEQQRIPFEESQYKCSETSHSSSLTQNMRNNSE-----EKP 352

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSAT 167
           F+C +C +       L+AHQ  H  E      Y+C +C + F      V+H++       
Sbjct: 353 FECNQCGKSFSWSSHLVAHQRTHTGEKP----YECSECGKSFSRSSHLVSHQR------- 401

Query: 168 VAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEE 227
                                 +    +PY C +C    +     + HQ TH        
Sbjct: 402 ----------------------THTGEKPYRCNQCGKSFSQSYVLVVHQRTHTG------ 433

Query: 228 RNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGA 287
                  E+  E ++      +  + +A            T      C  C +    +  
Sbjct: 434 -------EKPYECNQCGKSFRQSYKLIAHQRTH-------TGEKPYECNQCGKSFIQSYK 479

Query: 288 RRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAAS 346
              H+R      +   P+ C+QC +SFS + +L AH R H G    EC  C K F  ++ 
Sbjct: 480 LIAHQRIH----TGEKPYECNQCGKSFSQSYKLVAHQRTHTGEKPFECNQCGKSFSWSSQ 535

Query: 347 LEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYH 405
           L  H R H GE  Y C +CG+ F     LV H+R HT    + C +CGK+FS     + H
Sbjct: 536 LVAHQRTHTGEKPYECSECGKSFNRSSHLVMHQRIHTGEKPYECNQCGKSFSQSYVLVVH 595

Query: 406 RRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVH 465
           +RTH G+             P E               C QC KSF  +S L++H+R   
Sbjct: 596 QRTHTGEK------------PYE---------------CSQCGKSFRQSSCLTQHQRTHT 628

Query: 466 GPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGA 525
           G  E+   C  CGK F     +  H RTHTGE+PF C  CGK F +   L RHQ THT  
Sbjct: 629 G--EKPFECNQCGKTFSLSARLIVHQRTHTGEKPFTCIQCGKAFINSYKLIRHQATHTEE 686

Query: 526 RPYQC 530
           + Y+C
Sbjct: 687 KLYEC 691



 Score =  125 bits (313), Expect = 2e-28
 Identities = 64/152 (42%), Positives = 84/152 (55%), Gaps = 19/152 (12%)

Query: 444 CPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCH 503
           C QC KSF+ +S L  H+R   G  E+ + C  CGK F +  H+ +H RTHTGE+P++C+
Sbjct: 355 CNQCGKSFSWSSHLVAHQRTHTG--EKPYECSECGKSFSRSSHLVSHQRTHTGEKPYRCN 412

Query: 504 SCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLP 563
            CGK+F+    L  HQ THTG +PY+C  CGK F QS  L  H+R H             
Sbjct: 413 QCGKSFSQSYVLVVHQRTHTGEKPYECNQCGKSFRQSYKLIAHQRTH------------- 459

Query: 564 ITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            TG   + PY C  CG+ F     L  HQR+H
Sbjct: 460 -TG---EKPYECNQCGKSFIQSYKLIAHQRIH 487



 Score =  115 bits (287), Expect = 2e-25
 Identities = 80/267 (29%), Positives = 121/267 (45%), Gaps = 28/267 (10%)

Query: 332 HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR 391
           H+  + +K +   A++  H +++  E  Y   +CG+     + L+   R  T +  +   
Sbjct: 218 HKHVSHAKKWHLNAAVNSHQKINENETLYENNECGKP-PQSIHLIQFTRTQTKDKCYGFS 276

Query: 392 CG-KTFSNMTKFLYHRRTHAGKS--GAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCS 448
              ++F + T    H + H G         G    P  +        P   +Q  C + S
Sbjct: 277 DRIQSFCHGTPLHIHEKIHGGGKTFDFKECGQVLNPKISH-NEQQRIPFEESQYKCSETS 335

Query: 449 KSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKT 508
            S    S L+++ R  +   E+   C  CGK F    H+  H RTHTGE+P++C  CGK+
Sbjct: 336 HS----SSLTQNMR--NNSEEKPFECNQCGKSFSWSSHLVAHQRTHTGEKPYECSECGKS 389

Query: 509 FASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLY 568
           F+  ++L  HQ THTG +PY+C  CGK F+QS  L  H+R H              TG  
Sbjct: 390 FSRSSHLVSHQRTHTGEKPYRCNQCGKSFSQSYVLVVHQRTH--------------TG-- 433

Query: 569 NKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            + PY C  CG+ FR    L  HQR H
Sbjct: 434 -EKPYECNQCGKSFRQSYKLIAHQRTH 459


>gi|167830431 zinc finger protein 530 [Homo sapiens]
          Length = 599

 Score =  210 bits (534), Expect = 4e-54
 Identities = 137/508 (26%), Positives = 203/508 (39%), Gaps = 133/508 (26%)

Query: 92  QNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPS 151
           ++V ++ +     E P++C EC +        L H+ AH R       ++C +C + F  
Sbjct: 223 KSVFIQHQRADSGERPYKCSECGKSFSQSSGFLRHRKAHGRTRT----HECSECGKSFSR 278

Query: 152 PELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEE 211
                 H++                                   PY+C EC         
Sbjct: 279 KTHLTQHQRVH-----------------------------TGERPYDCSECGKSFRQVSV 309

Query: 212 FLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGW 271
            ++HQ  H      E                                             
Sbjct: 310 LIQHQRVHTGERPYE--------------------------------------------- 324

Query: 272 AQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-G 330
              C +C +    +    +HR +AH+   +T P+ CS+C +SFS +  L  H R H G  
Sbjct: 325 ---CSECGKSFSHSTNLYRHR-SAHT---STRPYECSECGKSFSHSTNLFRHWRVHTGVR 377

Query: 331 THECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC 390
            +EC+ C K F     L  H R H GE  Y+C +CG+ FG +  L+ H+R HT    + C
Sbjct: 378 PYECSECGKAFSCNIYLIHHQRFHTGERPYVCSECGKSFGQKSVLIQHQRVHTGERPYEC 437

Query: 391 -RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSK 449
             CGK FS  +    HRR H                    T P           C +C K
Sbjct: 438 SECGKVFSQSSGLFRHRRAHT------------------KTKP---------YECSECEK 470

Query: 450 SFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTF 509
           SF+  + L RH+    G  ER + C VCGK F +  H+  H   HT ERP++C  CGK++
Sbjct: 471 SFSCKTDLIRHQTVHTG--ERPYECSVCGKSFIRKTHLIRHQTVHTNERPYECDECGKSY 528

Query: 510 ASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYN 569
           +  + L +H+  HTG RPY+C +CGK FT+ ++L QH+ +H              TG   
Sbjct: 529 SQSSALLQHRRVHTGERPYECRECGKSFTRKNHLIQHKTVH--------------TG--- 571

Query: 570 KSPYYCGTCGRWFRAMAGLRLHQRVHAR 597
           + PY C  CG+ F   +GL  H+RVH +
Sbjct: 572 ERPYECSECGKSFSQSSGLLRHRRVHVQ 599



 Score =  198 bits (504), Expect = 1e-50
 Identities = 113/312 (36%), Positives = 149/312 (47%), Gaps = 52/312 (16%)

Query: 290 QHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGG-THECTTCSKVFKKAASLE 348
           QH+R      S   P+ CS+C +SFS ++    H +AH    THEC+ C K F +   L 
Sbjct: 228 QHQRAD----SGERPYKCSECGKSFSQSSGFLRHRKAHGRTRTHECSECGKSFSRKTHLT 283

Query: 349 QHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRR 407
           QH R+H GE  Y C +CG+ F     L+ H+R HT    + C  CGK+FS+ T    HR 
Sbjct: 284 QHQRVHTGERPYDCSECGKSFRQVSVLIQHQRVHTGERPYECSECGKSFSHSTNLYRHRS 343

Query: 408 THAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGP 467
            H          +T P                    C +C KSF+ ++ L RH R   G 
Sbjct: 344 AHT---------STRP------------------YECSECGKSFSHSTNLFRHWRVHTGV 376

Query: 468 PERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARP 527
             R + C  CGK F   I++ +H R HTGERP+ C  CGK+F   + L +HQ  HTG RP
Sbjct: 377 --RPYECSECGKAFSCNIYLIHHQRFHTGERPYVCSECGKSFGQKSVLIQHQRVHTGERP 434

Query: 528 YQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAG 587
           Y+C +CGK F+QSS L +HRR H +                   PY C  C + F     
Sbjct: 435 YECSECGKVFSQSSGLFRHRRAHTK-----------------TKPYECSECEKSFSCKTD 477

Query: 588 LRLHQRVHARAR 599
           L  HQ VH   R
Sbjct: 478 LIRHQTVHTGER 489



 Score =  190 bits (483), Expect = 3e-48
 Identities = 122/406 (30%), Positives = 171/406 (42%), Gaps = 72/406 (17%)

Query: 196 PYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMA 255
           PY+C EC    +    FL H+  H        R    E  E  +         + +    
Sbjct: 238 PYKCSECGKSFSQSSGFLRHRKAH-------GRTRTHECSECGKSFSRKTHLTQHQRV-- 288

Query: 256 EVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFS 315
                       T      C +C +         QH+R      +   P+ CS+C +SFS
Sbjct: 289 -----------HTGERPYDCSECGKSFRQVSVLIQHQRVH----TGERPYECSECGKSFS 333

Query: 316 SANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELT 374
            +  L  H  AH     +EC+ C K F  + +L +H R+H G   Y C +CG+ F   + 
Sbjct: 334 HSTNLYRHRSAHTSTRPYECSECGKSFSHSTNLFRHWRVHTGVRPYECSECGKAFSCNIY 393

Query: 375 LVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPP 433
           L+ H+R HT    + C  CGK+F   +  + H+R H G+             P E     
Sbjct: 394 LIHHQRFHTGERPYVCSECGKSFGQKSVLIQHQRVHTGER------------PYE----- 436

Query: 434 PPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRT 493
                     C +C K F+ +S L RHRRA      + + C  C K F     +  H   
Sbjct: 437 ----------CSECGKVFSQSSGLFRHRRA--HTKTKPYECSECEKSFSCKTDLIRHQTV 484

Query: 494 HTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRP 553
           HTGERP++C  CGK+F    +L RHQ  HT  RPY+C +CGK ++QSS L QHRR+H   
Sbjct: 485 HTGERPYECSVCGKSFIRKTHLIRHQTVHTNERPYECDECGKSYSQSSALLQHRRVH--- 541

Query: 554 VAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
                      TG   + PY C  CG+ F     L  H+ VH   R
Sbjct: 542 -----------TG---ERPYECRECGKSFTRKNHLIQHKTVHTGER 573



 Score =  159 bits (401), Expect = 1e-38
 Identities = 100/313 (31%), Positives = 132/313 (42%), Gaps = 63/313 (20%)

Query: 304 PFHCSQCQRSFSSANRLQAHG------RAHVGGTH----------ECTTCSKVFKKAASL 347
           PF   +  R FS+ + L  H       R H    H          + T   K F++ +  
Sbjct: 167 PFTFGEVGRDFSATSGLLQHQVTPTIERPHSRIRHLRVPTGRKPLKYTESRKSFREKSVF 226

Query: 348 EQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHR 406
            QH R   GE  Y C +CG+ F      + HR+AH     H C  CGK+FS  T    H+
Sbjct: 227 IQHQRADSGERPYKCSECGKSFSQSSGFLRHRKAHGRTRTHECSECGKSFSRKTHLTQHQ 286

Query: 407 RTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHG 466
           R H G+                               C +C KSF   S L +H+R   G
Sbjct: 287 RVHTGE---------------------------RPYDCSECGKSFRQVSVLIQHQRVHTG 319

Query: 467 PPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGAR 526
             ER + C  CGK F    ++  H   HT  RP++C  CGK+F+   NL RH   HTG R
Sbjct: 320 --ERPYECSECGKSFSHSTNLYRHRSAHTSTRPYECSECGKSFSHSTNLFRHWRVHTGVR 377

Query: 527 PYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMA 586
           PY+C +CGK F+ +  L  H+R H              TG   + PY C  CG+ F   +
Sbjct: 378 PYECSECGKAFSCNIYLIHHQRFH--------------TG---ERPYVCSECGKSFGQKS 420

Query: 587 GLRLHQRVHARAR 599
            L  HQRVH   R
Sbjct: 421 VLIQHQRVHTGER 433



 Score =  136 bits (343), Expect = 5e-32
 Identities = 86/277 (31%), Positives = 116/277 (41%), Gaps = 62/277 (22%)

Query: 339 KVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHR------RAHTA-------- 384
           KV    AS   + R H     +   + GR F     L+ H+      R H+         
Sbjct: 147 KVDGDQASFMMNCRFHVSGKPFTFGEVGRDFSATSGLLQHQVTPTIERPHSRIRHLRVPT 206

Query: 385 --NPLHRCRCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQL 442
              PL      K+F   + F+ H+R  +G+                              
Sbjct: 207 GRKPLKYTESRKSFREKSVFIQHQRADSGER---------------------------PY 239

Query: 443 PCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQC 502
            C +C KSF+ +S   RHR+A HG   R H C  CGK F +  H+  H R HTGERP+ C
Sbjct: 240 KCSECGKSFSQSSGFLRHRKA-HGRT-RTHECSECGKSFSRKTHLTQHQRVHTGERPYDC 297

Query: 503 HSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRL 562
             CGK+F  ++ L +HQ  HTG RPY+C +CGK F+ S+NL +HR  H            
Sbjct: 298 SECGKSFRQVSVLIQHQRVHTGERPYECSECGKSFSHSTNLYRHRSAHT----------- 346

Query: 563 PITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
                 +  PY C  CG+ F     L  H RVH   R
Sbjct: 347 ------STRPYECSECGKSFSHSTNLFRHWRVHTGVR 377



 Score =  125 bits (315), Expect = 1e-28
 Identities = 110/460 (23%), Positives = 163/460 (35%), Gaps = 100/460 (21%)

Query: 49  SLFFQHHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGL 96
           S+F QH +       + CSECG  ++     L H++ H    + E     ++ + +    
Sbjct: 224 SVFIQHQRADSGERPYKCSECGKSFSQSSGFLRHRKAHGRTRTHECSECGKSFSRKTHLT 283

Query: 97  EPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWV 156
           + + V   E P+ C EC +       L+ HQ  H  E      Y+C +C + F       
Sbjct: 284 QHQRVHTGERPYDCSECGKSFRQVSVLIQHQRVHTGER----PYECSECGKSFSHSTNLY 339

Query: 157 AHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQ 216
            HR A H S                              PYEC EC    +       H 
Sbjct: 340 RHRSA-HTST----------------------------RPYECSECGKSFSHSTNLFRHW 370

Query: 217 GTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCG 276
             H          G+   E  +                   G+               C 
Sbjct: 371 RVH---------TGVRPYECSECGKAFSCNIYLIHHQRFHTGER-----------PYVCS 410

Query: 277 DCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHV-GGTHECT 335
           +C +         QH+R      +   P+ CS+C + FS ++ L  H RAH     +EC+
Sbjct: 411 ECGKSFGQKSVLIQHQRV----HTGERPYECSECGKVFSQSSGLFRHRRAHTKTKPYECS 466

Query: 336 TCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGK 394
            C K F     L +H  +H GE  Y C  CG+ F  +  L+ H+  HT    + C  CGK
Sbjct: 467 ECEKSFSCKTDLIRHQTVHTGERPYECSVCGKSFIRKTHLIRHQTVHTNERPYECDECGK 526

Query: 395 TFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASA 454
           ++S  +  L HRR H G+             P E               C +C KSF   
Sbjct: 527 SYSQSSALLQHRRVHTGE------------RPYE---------------CRECGKSFTRK 559

Query: 455 SRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTH 494
           + L +H+    G  ER + C  CGK F +   +  H R H
Sbjct: 560 NHLIQHKTVHTG--ERPYECSECGKSFSQSSGLLRHRRVH 597



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 65/321 (20%), Positives = 103/321 (32%), Gaps = 117/321 (36%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A + +++  HHQ        ++CSECG  +     ++ HQ  H               
Sbjct: 385 GKAFSCNIYLIHHQRFHTGERPYVCSECGKSFGQKSVLIQHQRVHT-------------- 430

Query: 95  GLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPEL 154
                     E P++C EC ++      L  H+ AH +       Y+C +C++ F     
Sbjct: 431 ---------GERPYECSECGKVFSQSSGLFRHRRAHTKTK----PYECSECEKSFSCKTD 477

Query: 155 WVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLE 214
            + H+                                    PYEC  C          + 
Sbjct: 478 LIRHQTV-----------------------------HTGERPYECSVCGKSFIRKTHLIR 508

Query: 215 HQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG 274
           HQ  H                  +E   E DE                            
Sbjct: 509 HQTVH-----------------TNERPYECDE---------------------------- 523

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHE 333
           CG   +    + A  QHRR      +   P+ C +C +SF+  N L  H   H G   +E
Sbjct: 524 CG---KSYSQSSALLQHRRV----HTGERPYECRECGKSFTRKNHLIQHKTVHTGERPYE 576

Query: 334 CTTCSKVFKKAASLEQHLRLH 354
           C+ C K F +++ L +H R+H
Sbjct: 577 CSECGKSFSQSSGLLRHRRVH 597



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 31/124 (25%), Positives = 48/124 (38%), Gaps = 32/124 (25%)

Query: 492 RTHTGERPFQCHSCGKTFASLANLSRHQLTHT---------------GARPYQCLDCGKR 536
           R H   +PF     G+ F++ + L +HQ+T T               G +P +  +  K 
Sbjct: 160 RFHVSGKPFTFGEVGRDFSATSGLLQHQVTPTIERPHSRIRHLRVPTGRKPLKYTESRKS 219

Query: 537 FTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHA 596
           F + S   QH+R                     + PY C  CG+ F   +G   H++ H 
Sbjct: 220 FREKSVFIQHQRADS-----------------GERPYKCSECGKSFSQSSGFLRHRKAHG 262

Query: 597 RART 600
           R RT
Sbjct: 263 RTRT 266



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 21/81 (25%), Positives = 37/81 (45%), Gaps = 5/81 (6%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EALTTQNVGLEPELVPGAEGPFQCG 111
           + C ECG  Y+    +L H+  H      E     ++ T +N  ++ + V   E P++C 
Sbjct: 519 YECDECGKSYSQSSALLQHRRVHTGERPYECRECGKSFTRKNHLIQHKTVHTGERPYECS 578

Query: 112 ECSQLILSPGELLAHQDAHLR 132
           EC +       LL H+  H++
Sbjct: 579 ECGKSFSQSSGLLRHRRVHVQ 599


>gi|148596977 zinc finger protein 31 [Homo sapiens]
          Length = 1043

 Score =  208 bits (530), Expect = 1e-53
 Identities = 128/408 (31%), Positives = 185/408 (45%), Gaps = 65/408 (15%)

Query: 230  GLEEEEEDDEEDEEDDEEMEDEEAMAEV-----------GDDAVGGDESTAGWAQGCGDC 278
            G E   ED+++  E D       A+++            G+D+   +E    W     + 
Sbjct: 625  GFEMRHEDEDQISEQDIFEGLPGALSKCPTEAVCQPLDWGEDSENENEDEGQWGNPSQE- 683

Query: 279  PQHQPSAGARRQHRRTAHSPAS-ATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTT 336
             Q Q S+      +   H     A  P+ C  C +SFS ++   AH R H G   ++C  
Sbjct: 684  -QWQESSSEEDLEKLIDHQGLYLAEKPYKCDTCMKSFSRSSHFIAHQRIHTGEKPYKCLE 742

Query: 337  CSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKT 395
            C K F   ++L  H R+H GE  Y C++CG+ F     L+ H+R HT    ++C  C K+
Sbjct: 743  CGKNFSDRSNLNTHQRIHTGEKPYKCLECGKSFSDHSNLITHQRIHTGEKPYKCGECWKS 802

Query: 396  FSNMTKFLYHRRTHAGKSGAPP----------------------TGATAPPAPAEPTPPP 433
            F+  +  L H+R H G  G P                       T  TAP  P   +   
Sbjct: 803  FNQSSNLLKHQRIHLG--GNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQSISKDL 860

Query: 434  PPPAPPAQ------LPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHV 487
              P P +         C +C +SF+ +S L  H+R   G  E+ + C  CGK F K   +
Sbjct: 861  NSPGPHSTNSGEKLYECSECGRSFSKSSALISHQRIHTG--EKPYECAECGKSFSKSSTL 918

Query: 488  RNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHR 547
             NH RTHTGE+P++C  CGK F+  + L  HQ  HTG +PY+CL+CGK F   SNL  H+
Sbjct: 919  ANHQRTHTGEKPYKCVDCGKCFSERSKLITHQRVHTGEKPYKCLECGKFFRDRSNLITHQ 978

Query: 548  RLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            R+H              TG   + PY C  CG+ F   + L +HQR+H
Sbjct: 979  RIH--------------TG---EKPYKCRECGKCFNQSSSLIIHQRIH 1009



 Score =  157 bits (396), Expect = 4e-38
 Identities = 86/274 (31%), Positives = 125/274 (45%), Gaps = 56/274 (20%)

Query: 304  PFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLR---------- 352
            P+ C +C +SF+ ++ L  H R H+GG   +C+     F ++ S   H R          
Sbjct: 793  PYKCGECWKSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQ 852

Query: 353  ---------------LHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTF 396
                            + GE  Y C +CGR F     L++H+R HT    + C  CGK+F
Sbjct: 853  PQSISKDLNSPGPHSTNSGEKLYECSECGRSFSKSSALISHQRIHTGEKPYECAECGKSF 912

Query: 397  SNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASR 456
            S  +    H+RTH G+                               C  C K F+  S+
Sbjct: 913  SKSSTLANHQRTHTGEK---------------------------PYKCVDCGKCFSERSK 945

Query: 457  LSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLS 516
            L  H+R   G  E+ ++C  CGK F+   ++  H R HTGE+P++C  CGK F   ++L 
Sbjct: 946  LITHQRVHTG--EKPYKCLECGKFFRDRSNLITHQRIHTGEKPYKCRECGKCFNQSSSLI 1003

Query: 517  RHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLH 550
             HQ  HTG +PY+C +CGK F  SS+   HRR H
Sbjct: 1004 IHQRIHTGEKPYKCTECGKDFNNSSHFSAHRRTH 1037



 Score =  140 bits (352), Expect = 5e-33
 Identities = 126/537 (23%), Positives = 201/537 (37%), Gaps = 113/537 (21%)

Query: 3    EVVAEVAEMPTQMSPGAVEMSTPMSAEMMEMSTE--VTEMTPG-------EALASSLFFQ 53
            EV  E A  P+ + P A +M   M  E  +  +E  + E  PG       EA+   L + 
Sbjct: 605  EVANEDAVKPSTLCPKAPDMGFEMRHEDEDQISEQDIFEGLPGALSKCPTEAVCQPLDWG 664

Query: 54   HHQFMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGEC 113
                  +E    +         QEQ   + SEE+        ++ + +  AE P++C  C
Sbjct: 665  EDSENENEDEGQWGN-----PSQEQWQESSSEEDLEKL----IDHQGLYLAEKPYKCDTC 715

Query: 114  SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
             +        +AHQ  H  E      Y+C +C + F        H++             
Sbjct: 716  MKSFSRSSHFIAHQRIHTGEKP----YKCLECGKNFSDRSNLNTHQRIH----------- 760

Query: 174  PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEE 233
                                 +PY+C EC    +     + HQ  H    EK  + G   
Sbjct: 761  ------------------TGEKPYKCLECGKSFSDHSNLITHQRIHTG--EKPYKCGECW 800

Query: 234  EEEDDEEDEEDDEEME---DEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQ 290
            +  +   +    + +    + +  +E G +       +A W     +    QP + ++  
Sbjct: 801  KSFNQSSNLLKHQRIHLGGNPDQCSEPGGNFAQSPSFSAHWRNSTEETAPEQPQSISKDL 860

Query: 291  HRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQH 350
            +    HS  S    + CS+C RS                           F K+++L  H
Sbjct: 861  NSPGPHSTNSGEKLYECSECGRS---------------------------FSKSSALISH 893

Query: 351  LRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTH 409
             R+H GE  Y C +CG+ F    TL  H+R HT    ++C  CGK FS  +K + H+R H
Sbjct: 894  QRIHTGEKPYECAECGKSFSKSSTLANHQRTHTGEKPYKCVDCGKCFSERSKLITHQRVH 953

Query: 410  AGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPE 469
             G+                               C +C K F   S L  H+R   G  E
Sbjct: 954  TGEK---------------------------PYKCLECGKFFRDRSNLITHQRIHTG--E 984

Query: 470  RRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGAR 526
            + ++C  CGK F +   +  H R HTGE+P++C  CGK F + ++ S H+ TH G +
Sbjct: 985  KPYKCRECGKCFNQSSSLIIHQRIHTGEKPYKCTECGKDFNNSSHFSAHRRTHAGGK 1041


>gi|48717244 zinc finger protein 782 [Homo sapiens]
          Length = 699

 Score =  207 bits (526), Expect = 3e-53
 Identities = 114/309 (36%), Positives = 155/309 (50%), Gaps = 50/309 (16%)

Query: 304 PFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLC 362
           P+ C +C ++FS  +RL+ H R H G   ++C  C K F   + L  H R H GE  + C
Sbjct: 393 PYECPECGKAFSEKSRLRKHQRTHTGEKPYKCDGCDKAFSAKSGLRIHQRTHTGEKPFEC 452

Query: 363 VDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAG---------- 411
            +CG+ F  +  L+ H+R HT      C  CGK+FS+M+    HRRTH G          
Sbjct: 453 HECGKSFNYKSILIVHQRTHTGEKPFECNECGKSFSHMSGLRNHRRTHTGERPYKCDECG 512

Query: 412 -----KSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHG 466
                KSG      T        T   P         C QC K+F   S+L  H R   G
Sbjct: 513 KAFKLKSGLRKHHRTH-------TGEKP-------YKCNQCGKAFGQKSQLRGHHRIHTG 558

Query: 467 PPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGAR 526
             E+ ++C  CG+ F +  ++R H RTHTGE+P+QC  CGKTF   +NL  HQ THTG +
Sbjct: 559 --EKPYKCNHCGEAFSQKSNLRVHHRTHTGEKPYQCEECGKTFRQKSNLRGHQRTHTGEK 616

Query: 527 PYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMA 586
           PY+C +CGK F++ S L++H+R H              TG   + PY C  CG  F   +
Sbjct: 617 PYECNECGKAFSEKSVLRKHQRTH--------------TG---EKPYNCNQCGEAFSQKS 659

Query: 587 GLRLHQRVH 595
            LR+HQR H
Sbjct: 660 NLRVHQRTH 668



 Score =  194 bits (493), Expect = 2e-49
 Identities = 114/358 (31%), Positives = 164/358 (45%), Gaps = 55/358 (15%)

Query: 195 EPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAM 254
           +PYECPEC    +      +HQ TH            E+  + D  D+          A 
Sbjct: 392 KPYECPECGKAFSEKSRLRKHQRTHTG----------EKPYKCDGCDK----------AF 431

Query: 255 AEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSF 314
           +      +     T      C +C +          H+RT     +   PF C++C +SF
Sbjct: 432 SAKSGLRIHQRTHTGEKPFECHECGKSFNYKSILIVHQRTH----TGEKPFECNECGKSF 487

Query: 315 SSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTEL 373
           S  + L+ H R H G   ++C  C K FK  + L +H R H GE  Y C  CG+ FG + 
Sbjct: 488 SHMSGLRNHRRTHTGERPYKCDECGKAFKLKSGLRKHHRTHTGEKPYKCNQCGKAFGQKS 547

Query: 374 TLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPP 432
            L  H R HT    ++C  CG+ FS  +    H RTH G+                    
Sbjct: 548 QLRGHHRIHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTGEK------------------- 588

Query: 433 PPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLR 492
                 P Q  C +C K+F   S L  H+R   G  E+ + C  CGK F +   +R H R
Sbjct: 589 ------PYQ--CEECGKTFRQKSNLRGHQRTHTG--EKPYECNECGKAFSEKSVLRKHQR 638

Query: 493 THTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLH 550
           THTGE+P+ C+ CG+ F+  +NL  HQ THTG +PY+C  CG+ F+Q S+L++H++ H
Sbjct: 639 THTGEKPYNCNQCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSSLREHQKAH 696



 Score =  166 bits (421), Expect = 5e-41
 Identities = 105/326 (32%), Positives = 151/326 (46%), Gaps = 25/326 (7%)

Query: 287 ARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTH-ECTTCSKVFKKAA 345
           +++ H R  H       PF      +SF+  + L  H R H    + +   C++ F   +
Sbjct: 295 SQKSHIREHHRVHIGVKPFEYG---KSFNRNSTLPVHQRTHATDKYSDYHPCTETFSYQS 351

Query: 346 SLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLY 404
           +   H ++H     Y   +CG+       L+  +++HT    + C  CGK FS  ++   
Sbjct: 352 TFSVHQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKPYECPECGKAFSEKSRLRK 411

Query: 405 HRRTHAGKSGAPPTGA-TAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRA 463
           H+RTH G+      G   A  A +                C +C KSF   S L  H+R 
Sbjct: 412 HQRTHTGEKPYKCDGCDKAFSAKSGLRIHQRTHTGEKPFECHECGKSFNYKSILIVHQRT 471

Query: 464 VHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHT 523
             G  E+   C  CGK F  +  +RNH RTHTGERP++C  CGK F   + L +H  THT
Sbjct: 472 HTG--EKPFECNECGKSFSHMSGLRNHRRTHTGERPYKCDECGKAFKLKSGLRKHHRTHT 529

Query: 524 GARPYQCLDCGKRFTQSSNLQQHRRLHL--RPV-------AFARAPRLPI-----TGLYN 569
           G +PY+C  CGK F Q S L+ H R+H   +P        AF++   L +     TG   
Sbjct: 530 GEKPYKCNQCGKAFGQKSQLRGHHRIHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTG--- 586

Query: 570 KSPYYCGTCGRWFRAMAGLRLHQRVH 595
           + PY C  CG+ FR  + LR HQR H
Sbjct: 587 EKPYQCEECGKTFRQKSNLRGHQRTH 612



 Score =  159 bits (403), Expect = 6e-39
 Identities = 117/473 (24%), Positives = 175/473 (36%), Gaps = 124/473 (26%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELV-----PGAEGPFQCGEC 113
           C+E  S  +T      HQ+ H+ A   E     ++  +   L+        E P++C EC
Sbjct: 343 CTETFSYQSTFSV---HQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKPYECPEC 399

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
            +       L  HQ  H  E      Y+C  C + F +      H++             
Sbjct: 400 GKAFSEKSRLRKHQRTHTGEK----PYKCDGCDKAFSAKSGLRIHQR------------- 442

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEE 233
                           +    +P+EC EC          + HQ TH      E       
Sbjct: 443 ----------------THTGEKPFECHECGKSFNYKSILIVHQRTHTGEKPFE------- 479

Query: 234 EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRR 293
                                                    C +C +        R HRR
Sbjct: 480 -----------------------------------------CNECGKSFSHMSGLRNHRR 498

Query: 294 TAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLR 352
           T     +   P+ C +C ++F   + L+ H R H G   ++C  C K F + + L  H R
Sbjct: 499 T----HTGERPYKCDECGKAFKLKSGLRKHHRTHTGEKPYKCNQCGKAFGQKSQLRGHHR 554

Query: 353 LHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAG 411
           +H GE  Y C  CG  F  +  L  H R HT    ++C  CGKTF   +    H+RTH G
Sbjct: 555 IHTGEKPYKCNHCGEAFSQKSNLRVHHRTHTGEKPYQCEECGKTFRQKSNLRGHQRTHTG 614

Query: 412 KSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERR 471
           +             P E               C +C K+F+  S L +H+R   G  E+ 
Sbjct: 615 EK------------PYE---------------CNECGKAFSEKSVLRKHQRTHTG--EKP 645

Query: 472 HRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTG 524
           + C  CG+ F +  ++R H RTHTGE+P++C  CG+TF+  ++L  HQ  H G
Sbjct: 646 YNCNQCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSSLREHQKAHPG 698



 Score =  158 bits (399), Expect = 2e-38
 Identities = 93/276 (33%), Positives = 133/276 (48%), Gaps = 42/276 (15%)

Query: 331 THECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC 390
           TH+  T  K F + + + +H R+H G   +   + G+ F    TL  H+R H  +     
Sbjct: 284 THKTLTGGKSFSQKSHIREHHRVHIGVKPF---EYGKSFNRNSTLPVHQRTHATDKYSDY 340

Query: 391 R-CGKTFSNMTKFLYHRRTH----------AGKSGAPPTGATAPPAPAEPTPPPPPPAPP 439
             C +TFS  + F  H++ H           GKS +  +    P        P       
Sbjct: 341 HPCTETFSYQSTFSVHQKVHIRAKPYEYNECGKSCSMNSHLIWPQKSHTGEKP------- 393

Query: 440 AQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERP 499
               CP+C K+F+  SRL +H+R   G  E+ ++C  C K F     +R H RTHTGE+P
Sbjct: 394 --YECPECGKAFSEKSRLRKHQRTHTG--EKPYKCDGCDKAFSAKSGLRIHQRTHTGEKP 449

Query: 500 FQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARA 559
           F+CH CGK+F   + L  HQ THTG +P++C +CGK F+  S L+ HRR H         
Sbjct: 450 FECHECGKSFNYKSILIVHQRTHTGEKPFECNECGKSFSHMSGLRNHRRTH--------- 500

Query: 560 PRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
                TG   + PY C  CG+ F+  +GLR H R H
Sbjct: 501 -----TG---ERPYKCDECGKAFKLKSGLRKHHRTH 528



 Score =  107 bits (267), Expect = 4e-23
 Identities = 80/362 (22%), Positives = 131/362 (36%), Gaps = 64/362 (17%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + C ECG  ++    +  HQ  H                         E P++C  C + 
Sbjct: 394 YECPECGKAFSEKSRLRKHQRTHT-----------------------GEKPYKCDGCDKA 430

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
             +   L  HQ  H  E      ++C +C + F    + + H++                
Sbjct: 431 FSAKSGLRIHQRTHTGEKP----FECHECGKSFNYKSILIVHQR---------------- 470

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLE-KEERNGLEEEE 235
                        +    +P+EC EC    +       H+ TH      K +  G   + 
Sbjct: 471 -------------THTGEKPFECNECGKSFSHMSGLRNHRRTHTGERPYKCDECGKAFKL 517

Query: 236 EDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQ-GCGDCP---QHQPSAGARRQH 291
           +            E      + G  A G      G  +   G+ P    H   A +++ +
Sbjct: 518 KSGLRKHHRTHTGEKPYKCNQCGK-AFGQKSQLRGHHRIHTGEKPYKCNHCGEAFSQKSN 576

Query: 292 RRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQH 350
            R  H   +   P+ C +C ++F   + L+ H R H G   +EC  C K F + + L +H
Sbjct: 577 LRVHHRTHTGEKPYQCEECGKTFRQKSNLRGHQRTHTGEKPYECNECGKAFSEKSVLRKH 636

Query: 351 LRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTH 409
            R H GE  Y C  CG  F  +  L  H+R HT    ++C +CG+TFS  +    H++ H
Sbjct: 637 QRTHTGEKPYNCNQCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKSSLREHQKAH 696

Query: 410 AG 411
            G
Sbjct: 697 PG 698



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 63/312 (20%), Positives = 100/312 (32%), Gaps = 101/312 (32%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPG---------AEGP 107
           F C+ECG  ++ +  + +H+  H    + E        G   +L  G          E P
Sbjct: 478 FECNECGKSFSHMSGLRNHRRTH----TGERPYKCDECGKAFKLKSGLRKHHRTHTGEKP 533

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPE-LWVAHRKAQHLSA 166
           ++C +C +      +L  H   H  E      Y+C  C E F     L V HR       
Sbjct: 534 YKCNQCGKAFGQKSQLRGHHRIHTGEKP----YKCNHCGEAFSQKSNLRVHHR------- 582

Query: 167 TVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKE 226
                                  +    +PY+C EC            HQ TH      E
Sbjct: 583 -----------------------THTGEKPYQCEECGKTFRQKSNLRGHQRTHTGEKPYE 619

Query: 227 ERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAG 286
                                                           C +C +      
Sbjct: 620 ------------------------------------------------CNECGKAFSEKS 631

Query: 287 ARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAA 345
             R+H+RT     +   P++C+QC  +FS  + L+ H R H G   ++C  C + F + +
Sbjct: 632 VLRKHQRTH----TGEKPYNCNQCGEAFSQKSNLRVHQRTHTGEKPYKCDKCGRTFSQKS 687

Query: 346 SLEQHLRLHRGE 357
           SL +H + H G+
Sbjct: 688 SLREHQKAHPGD 699



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 20/94 (21%)

Query: 506 GKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPIT 565
           GK+F+  +++  H   H G +P++    GK F ++S L  H+R H              T
Sbjct: 291 GKSFSQKSHIREHHRVHIGVKPFEY---GKSFNRNSTLPVHQRTHA-------------T 334

Query: 566 GLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
             Y  S Y+   C   F   +   +HQ+VH RA+
Sbjct: 335 DKY--SDYH--PCTETFSYQSTFSVHQKVHIRAK 364


>gi|38348236 zinc finger protein 497 [Homo sapiens]
          Length = 498

 Score =  206 bits (525), Expect = 4e-53
 Identities = 123/345 (35%), Positives = 162/345 (46%), Gaps = 32/345 (9%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           CG+C +         QHRR      +   P+ C +C ++F+ ++ L  H R H G   + 
Sbjct: 108 CGECGKAFSQGSYLLQHRRVH----TGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYA 163

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RC 392
           C  C K F+  + L  H   H G   + C DCG+ FG   TLV HRR HT    + C  C
Sbjct: 164 CRECGKAFRAQSQLIHHQETHSGLKPFRCPDCGKSFGRSTTLVQHRRTHTGEKPYECPEC 223

Query: 393 GKTFSNMTKFLYHRRTHAGKS--GAPPTGATAPPAP--AEPTPPPPPPAPPAQLPCPQCS 448
           GK FS  + FL HRR H G         G     +   AE         P A   CP C 
Sbjct: 224 GKAFSWNSNFLEHRRVHTGARPHACRDCGKAFSQSSNLAEHLKIHAGARPHA---CPDCG 280

Query: 449 KSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKT 508
           K+F   + L +HRR      E+   C  CGK F++   +  H RTHTGERPF+C  CG+ 
Sbjct: 281 KAFVRVAGLRQHRRTHSS--EKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQA 338

Query: 509 FASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAP-------- 560
           F   + L+ H+  HTG +P+ C  CGK  +Q SNL  HRR H     FA A         
Sbjct: 339 FVMGSYLAEHRRVHTGEKPHACAQCGKASSQRSNLLSHRRTHSGAKPFACADCGKAFRGS 398

Query: 561 ------RLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
                 RL  TG   + P+ C  CG+ FR  + LR HQR+H+  R
Sbjct: 399 SGLAHHRLSHTG---ERPFACAECGKAFRGSSELRQHQRLHSGER 440



 Score =  206 bits (524), Expect = 6e-53
 Identities = 149/516 (28%), Positives = 209/516 (40%), Gaps = 134/516 (25%)

Query: 96  LEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELW 155
           L P  +P   G  +CGEC +       LL H+  H  E      Y C +C + F     W
Sbjct: 95  LRPSPLPEEPG-CRCGECGKAFSQGSYLLQHRRVHTGEKP----YTCPECGKAFA----W 145

Query: 156 VAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEH 215
            ++  +QH      E                        +PY C EC        + + H
Sbjct: 146 SSNL-SQHQRIHSGE------------------------KPYACRECGKAFRAQSQLIHH 180

Query: 216 QGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGC 275
           Q TH         +GL+                                          C
Sbjct: 181 QETH---------SGLKPFR---------------------------------------C 192

Query: 276 GDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HEC 334
            DC +    +    QHRRT     +   P+ C +C ++FS  +    H R H G   H C
Sbjct: 193 PDCGKSFGRSTTLVQHRRTH----TGEKPYECPECGKAFSWNSNFLEHRRVHTGARPHAC 248

Query: 335 TTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCG 393
             C K F ++++L +HL++H G   + C DCG+ F     L  HRR H++     C  CG
Sbjct: 249 RDCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGLRQHRRTHSSEKPFPCAECG 308

Query: 394 KTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFAS 453
           K F   ++ L H+RTH G+             P E               C +C ++F  
Sbjct: 309 KAFRESSQLLQHQRTHTGER------------PFE---------------CAECGQAFVM 341

Query: 454 ASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLA 513
            S L+ HRR   G  E+ H C  CGK   +  ++ +H RTH+G +PF C  CGK F   +
Sbjct: 342 GSYLAEHRRVHTG--EKPHACAQCGKASSQRSNLLSHRRTHSGAKPFACADCGKAFRGSS 399

Query: 514 NLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHL--RPV-------AFAR-----A 559
            L+ H+L+HTG RP+ C +CGK F  SS L+QH+RLH   RP        AF R     +
Sbjct: 400 GLAHHRLSHTGERPFACAECGKAFRGSSELRQHQRLHSGERPFVCAHCSKAFVRKSELLS 459

Query: 560 PRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            R   TG   + PY CG CG+ F     L  HQ+ H
Sbjct: 460 HRRTHTG---ERPYACGECGKPFSHRCNLNEHQKRH 492



 Score =  180 bits (456), Expect = 4e-45
 Identities = 124/477 (25%), Positives = 187/477 (39%), Gaps = 101/477 (21%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGL---------EPELVPGAEGPFQ 109
           C ECG  ++    +L H+  H    + E+  T    G          + + +   E P+ 
Sbjct: 108 CGECGKAFSQGSYLLQHRRVH----TGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYA 163

Query: 110 CGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVA 169
           C EC +   +  +L+ HQ+ H    +    ++C DC + F      V HR+         
Sbjct: 164 CRECGKAFRAQSQLIHHQETH----SGLKPFRCPDCGKSFGRSTTLVQHRR--------- 210

Query: 170 EPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERN 229
                               +    +PYECPEC    +    FLEH+  H  +     R 
Sbjct: 211 --------------------THTGEKPYECPECGKAFSWNSNFLEHRRVHTGARPHACR- 249

Query: 230 GLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARR 289
                              +  +A ++  + A             C DC +        R
Sbjct: 250 -------------------DCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGLR 290

Query: 290 QHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLE 348
           QHRRT     S+  PF C++C ++F  +++L  H R H G    EC  C + F   + L 
Sbjct: 291 QHRRTH----SSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAFVMGSYLA 346

Query: 349 QHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHT-ANPLHRCRCGKTFSNMTKFLYHRR 407
           +H R+H GE  + C  CG+       L++HRR H+ A P     CGK F   +   +HR 
Sbjct: 347 EHRRVHTGEKPHACAQCGKASSQRSNLLSHRRTHSGAKPFACADCGKAFRGSSGLAHHRL 406

Query: 408 THAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGP 467
           +H G+                               C +C K+F  +S L +H+R   G 
Sbjct: 407 SHTGER---------------------------PFACAECGKAFRGSSELRQHQRLHSG- 438

Query: 468 PERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTG 524
            ER   C  C K F +   + +H RTHTGERP+ C  CGK F+   NL+ HQ  H G
Sbjct: 439 -ERPFVCAHCSKAFVRKSELLSHRRTHTGERPYACGECGKPFSHRCNLNEHQKRHGG 494



 Score =  127 bits (318), Expect = 4e-29
 Identities = 71/189 (37%), Positives = 97/189 (51%), Gaps = 24/189 (12%)

Query: 411 GKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPER 470
           G+ GA P    + PA     P P P  P  +  C +C K+F+  S L +HRR   G  E+
Sbjct: 80  GRDGAGPR---SEPADRALRPSPLPEEPGCR--CGECGKAFSQGSYLLQHRRVHTG--EK 132

Query: 471 RHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQC 530
            + C  CGK F    ++  H R H+GE+P+ C  CGK F + + L  HQ TH+G +P++C
Sbjct: 133 PYTCPECGKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAQSQLIHHQETHSGLKPFRC 192

Query: 531 LDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRL 590
            DCGK F +S+ L QHRR H              TG   + PY C  CG+ F   +    
Sbjct: 193 PDCGKSFGRSTTLVQHRRTH--------------TG---EKPYECPECGKAFSWNSNFLE 235

Query: 591 HQRVHARAR 599
           H+RVH  AR
Sbjct: 236 HRRVHTGAR 244



 Score =  116 bits (291), Expect = 6e-26
 Identities = 97/386 (25%), Positives = 140/386 (36%), Gaps = 44/386 (11%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNV 94
           G+A A S     HQ        + C ECG  +    +++ HQE H            ++ 
Sbjct: 140 GKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAQSQLIHHQETHSGLKPFRCPDCGKSF 199

Query: 95  GLEPELVPG-----AEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
           G    LV        E P++C EC +        L H+  H         + C DC + F
Sbjct: 200 GRSTTLVQHRRTHTGEKPYECPECGKAFSWNSNFLEHRRVH----TGARPHACRDCGKAF 255

Query: 150 PSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATP 209
                   H K    +   A P           L         + +P+ C EC       
Sbjct: 256 SQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGLRQHRRTHSSE-KPFPCAECGKAFRES 314

Query: 210 EEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTA 269
            + L+HQ TH                      E   E  E  +A       A      T 
Sbjct: 315 SQLLQHQRTH--------------------TGERPFECAECGQAFVMGSYLAEHRRVHTG 354

Query: 270 GWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG 329
                C  C +          HRRT HS A    PF C+ C ++F  ++ L  H  +H G
Sbjct: 355 EKPHACAQCGKASSQRSNLLSHRRT-HSGAK---PFACADCGKAFRGSSGLAHHRLSHTG 410

Query: 330 GT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLH 388
                C  C K F+ ++ L QH RLH GE  ++C  C + F  +  L++HRR HT    +
Sbjct: 411 ERPFACAECGKAFRGSSELRQHQRLHSGERPFVCAHCSKAFVRKSELLSHRRTHTGERPY 470

Query: 389 RC-RCGKTFSNMTKFLYHRRTHAGKS 413
            C  CGK FS+      H++ H G++
Sbjct: 471 ACGECGKPFSHRCNLNEHQKRHGGRA 496


>gi|33859678 zinc finger protein 416 [Homo sapiens]
          Length = 594

 Score =  206 bits (525), Expect = 4e-53
 Identities = 125/353 (35%), Positives = 165/353 (46%), Gaps = 50/353 (14%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           C +C +          HRR      +   P+ C QC +SFS    L  H R H G   +E
Sbjct: 272 CSECGKSFSQTSHLNDHRRIH----TGERPYVCGQCGKSFSQRATLIKHHRVHTGERPYE 327

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RC 392
           C  C K F ++++L +H R+H GE  Y C +CG+ FG++ TLV H+R HT    + C  C
Sbjct: 328 CGECGKSFSQSSNLIEHCRIHTGERPYECDECGKAFGSKSTLVRHQRTHTGEKPYECGEC 387

Query: 393 GKTFSNMTKFLYHRRTHA----------GKSGAPPTGATAPPAPAEPTPPPPPPAPPAQL 442
           GK F      + H+R H           GKS +   G            P          
Sbjct: 388 GKLFRQSFSLVVHQRIHTTARPYECGQCGKSFSLKCGLIQHQLIHSGARP---------F 438

Query: 443 PCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQC 502
            C +C KSF+  + L++H + VH   ER + CG CGK F     +  H RTHTGERPF+C
Sbjct: 439 ECDECGKSFSQRTTLNKHHK-VH-TAERPYVCGECGKAFMFKSKLVRHQRTHTGERPFEC 496

Query: 503 HSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRL 562
             CGK F     L  HQ  HTG RPY C  CGK F Q S+L QH+ +H            
Sbjct: 497 SECGKFFRQSYTLVEHQKIHTGLRPYDCGQCGKSFIQKSSLIQHQVVH------------ 544

Query: 563 PITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARARTLTLQPPRSPSPAPPP 615
             TG   + PY CG CG+ F   +GL LH++ H      T++ PR  S    P
Sbjct: 545 --TG---ERPYECGKCGKSFTQHSGLILHRKSH------TVERPRDSSKCGKP 586



 Score =  128 bits (322), Expect = 1e-29
 Identities = 72/168 (42%), Positives = 93/168 (55%), Gaps = 19/168 (11%)

Query: 446 QCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSC 505
           +C K+      L + +R VH P ER + C  CGK F +  H+ +H R HTGERP+ C  C
Sbjct: 246 KCGKACCCECSLVQLQR-VH-PGERPYECSECGKSFSQTSHLNDHRRIHTGERPYVCGQC 303

Query: 506 GKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHL--RPV-------AF 556
           GK+F+  A L +H   HTG RPY+C +CGK F+QSSNL +H R+H   RP        AF
Sbjct: 304 GKSFSQRATLIKHHRVHTGERPYECGECGKSFSQSSNLIEHCRIHTGERPYECDECGKAF 363

Query: 557 ARAPRL-----PITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
                L       TG   + PY CG CG+ FR    L +HQR+H  AR
Sbjct: 364 GSKSTLVRHQRTHTG---EKPYECGECGKLFRQSFSLVVHQRIHTTAR 408



 Score =  127 bits (319), Expect = 3e-29
 Identities = 107/461 (23%), Positives = 155/461 (33%), Gaps = 139/461 (30%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + CSECG  ++    +  H+  H                         E P+ CG+C + 
Sbjct: 270 YECSECGKSFSQTSHLNDHRRIHT-----------------------GERPYVCGQCGKS 306

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
                 L+ H   H  E      Y+C +C + F      + H +                
Sbjct: 307 FSQRATLIKHHRVHTGER----PYECGECGKSFSQSSNLIEHCRI--------------- 347

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE 236
                              PYEC EC     +    + HQ TH      E          
Sbjct: 348 --------------HTGERPYECDECGKAFGSKSTLVRHQRTHTGEKPYE---------- 383

Query: 237 DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAH 296
                                                 CG+C +    + +   H+R  H
Sbjct: 384 --------------------------------------CGECGKLFRQSFSLVVHQR-IH 404

Query: 297 SPASATHPFHCSQCQRSFSSANRLQAHGRAHVGG-THECTTCSKVFKKAASLEQHLRLHR 355
           + A    P+ C QC +SFS    L  H   H G    EC  C K F +  +L +H ++H 
Sbjct: 405 TTA---RPYECGQCGKSFSLKCGLIQHQLIHSGARPFECDECGKSFSQRTTLNKHHKVHT 461

Query: 356 GEARYLCVDCGRGFGTELTLVAHRRAHTA-NPLHRCRCGKTFSNMTKFLYHRRTHAGKSG 414
            E  Y+C +CG+ F  +  LV H+R HT   P     CGK F      + H++ H G   
Sbjct: 462 AERPYVCGECGKAFMFKSKLVRHQRTHTGERPFECSECGKFFRQSYTLVEHQKIHTGL-- 519

Query: 415 APPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRC 474
                                        C QC KSF   S L +H + VH   ER + C
Sbjct: 520 -------------------------RPYDCGQCGKSFIQKSSLIQH-QVVH-TGERPYEC 552

Query: 475 GVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANL 515
           G CGK F +   +  H ++HT ERP     CGK ++  +N+
Sbjct: 553 GKCGKSFTQHSGLILHRKSHTVERPRDSSKCGKPYSPRSNI 593



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 44/114 (38%), Positives = 57/114 (50%), Gaps = 17/114 (14%)

Query: 486 HVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQ 545
           H   H R  TG+R ++   CGK      +L + Q  H G RPY+C +CGK F+Q+S+L  
Sbjct: 228 HTFFHPRVCTGKRLYESSKCGKACCCECSLVQLQRVHPGERPYECSECGKSFSQTSHLND 287

Query: 546 HRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           HRR+H              TG   + PY CG CG+ F   A L  H RVH   R
Sbjct: 288 HRRIH--------------TG---ERPYVCGQCGKSFSQRATLIKHHRVHTGER 324


>gi|4507975 zinc finger protein 345 [Homo sapiens]
          Length = 488

 Score =  206 bits (524), Expect = 6e-53
 Identities = 141/539 (26%), Positives = 206/539 (38%), Gaps = 156/539 (28%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLIL 118
           C ECG  ++ +  ++ HQ  H                         E P++C EC +   
Sbjct: 64  CKECGKDFSFVSVLVRHQRIHT-----------------------GEKPYECKECGKAFG 100

Query: 119 SPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLP 178
           S   L  HQ  H  E      ++C +C + F S      H++                  
Sbjct: 101 SGANLAYHQRIHTGEKP----FECKECGKAFGSGSNLTHHQRIH---------------- 140

Query: 179 PPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDD 238
                           +PYEC EC    +     + HQ  H      E            
Sbjct: 141 -------------TGEKPYECKECGKAFSFGSGLIRHQIIHSGEKPYE------------ 175

Query: 239 EEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSP 298
                                               C +C +      A  +H R     
Sbjct: 176 ------------------------------------CKECGKSFSFESALIRHHRIH--- 196

Query: 299 ASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGE 357
            +   P+ C  C ++F S + L  H R H G   +EC  C   F   ++L +H R+H GE
Sbjct: 197 -TGEKPYECIDCGKAFGSGSNLTQHRRIHTGEKPYECKACGMAFSSGSALTRHQRIHTGE 255

Query: 358 ARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAP 416
             Y+C +CG+ F     L  H+R HT    + C+ CGK F++ +    H+R H G+    
Sbjct: 256 KPYICNECGKAFSFGSALTRHQRIHTGEKPYVCKECGKAFNSGSDLTQHQRIHTGEK--- 312

Query: 417 PTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGV 476
                    P E               C +C K+F S S+L +H+R   G  E+ + C  
Sbjct: 313 ---------PYE---------------CKECEKAFRSGSKLIQHQRMHTG--EKPYECKE 346

Query: 477 CGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKR 536
           CGK F     +  H R HTGE+P++C  CGK F S + L +HQL HTG RPY+C +CGK 
Sbjct: 347 CGKTFSSGSDLTQHHRIHTGEKPYECKECGKAFGSGSKLIQHQLIHTGERPYECKECGKS 406

Query: 537 FTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
           F+  S L +H+R+H              TG   + PY C  CG+ F + + L  HQR+H
Sbjct: 407 FSSGSALNRHQRIH--------------TG---EKPYECKECGKAFYSGSSLTQHQRIH 448



 Score =  189 bits (481), Expect = 5e-48
 Identities = 111/335 (33%), Positives = 156/335 (46%), Gaps = 40/335 (11%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           C +C +   S      H+R      +   PF C +C ++F S + L  H R H G   +E
Sbjct: 92  CKECGKAFGSGANLAYHQRIH----TGEKPFECKECGKAFGSGSNLTHHQRIHTGEKPYE 147

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RC 392
           C  C K F   + L +H  +H GE  Y C +CG+ F  E  L+ H R HT    + C  C
Sbjct: 148 CKECGKAFSFGSGLIRHQIIHSGEKPYECKECGKSFSFESALIRHHRIHTGEKPYECIDC 207

Query: 393 GKTFSNMTKFLYHRRTHAGKSG--------APPTGATAPPAPAEPTPPPPPPAPPAQLPC 444
           GK F + +    HRR H G+          A  +G+         T   P         C
Sbjct: 208 GKAFGSGSNLTQHRRIHTGEKPYECKACGMAFSSGSALTRHQRIHTGEKP-------YIC 260

Query: 445 PQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHS 504
            +C K+F+  S L+RH+R   G  E+ + C  CGK F     +  H R HTGE+P++C  
Sbjct: 261 NECGKAFSFGSALTRHQRIHTG--EKPYVCKECGKAFNSGSDLTQHQRIHTGEKPYECKE 318

Query: 505 CGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPI 564
           C K F S + L +HQ  HTG +PY+C +CGK F+  S+L QH R+H              
Sbjct: 319 CEKAFRSGSKLIQHQRMHTGEKPYECKECGKTFSSGSDLTQHHRIH-------------- 364

Query: 565 TGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           TG   + PY C  CG+ F + + L  HQ +H   R
Sbjct: 365 TG---EKPYECKECGKAFGSGSKLIQHQLIHTGER 396



 Score =  188 bits (478), Expect = 1e-47
 Identities = 130/496 (26%), Positives = 192/496 (38%), Gaps = 111/496 (22%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + C ECG  + +   +  HQ  H                         E PF+C EC + 
Sbjct: 90  YECKECGKAFGSGANLAYHQRIHT-----------------------GEKPFECKECGKA 126

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
             S   L  HQ  H  E      Y+C +C + F      + H+                 
Sbjct: 127 FGSGSNLTHHQRIHTGEK----PYECKECGKAFSFGSGLIRHQIIHS------------- 169

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE 236
                             +PYEC EC    +     + H   H                 
Sbjct: 170 ----------------GEKPYECKECGKSFSFESALIRHHRIH----------------- 196

Query: 237 DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAH 296
                E+  E ++  +A     +        T      C  C     S  A  +H+R   
Sbjct: 197 ---TGEKPYECIDCGKAFGSGSNLTQHRRIHTGEKPYECKACGMAFSSGSALTRHQRI-- 251

Query: 297 SPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLRLHR 355
              +   P+ C++C ++FS  + L  H R H G   + C  C K F   + L QH R+H 
Sbjct: 252 --HTGEKPYICNECGKAFSFGSALTRHQRIHTGEKPYVCKECGKAFNSGSDLTQHQRIHT 309

Query: 356 GEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSG 414
           GE  Y C +C + F +   L+ H+R HT    + C+ CGKTFS+ +    H R H G+  
Sbjct: 310 GEKPYECKECEKAFRSGSKLIQHQRMHTGEKPYECKECGKTFSSGSDLTQHHRIHTGEK- 368

Query: 415 APPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRC 474
                      P E               C +C K+F S S+L +H+    G  ER + C
Sbjct: 369 -----------PYE---------------CKECGKAFGSGSKLIQHQLIHTG--ERPYEC 400

Query: 475 GVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCG 534
             CGK F     +  H R HTGE+P++C  CGK F S ++L++HQ  HTG + Y+C +CG
Sbjct: 401 KECGKSFSSGSALNRHQRIHTGEKPYECKECGKAFYSGSSLTQHQRIHTGEKLYECKNCG 460

Query: 535 KRFTQSSNLQQHRRLH 550
           K + + S  QQH++ H
Sbjct: 461 KAYGRDSEFQQHKKSH 476



 Score =  167 bits (423), Expect = 3e-41
 Identities = 95/274 (34%), Positives = 134/274 (48%), Gaps = 39/274 (14%)

Query: 333 ECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR- 391
           EC  C K F   + L +H R+H GE  Y C +CG+ FG+   L  H+R HT      C+ 
Sbjct: 63  ECKECGKDFSFVSVLVRHQRIHTGEKPYECKECGKAFGSGANLAYHQRIHTGEKPFECKE 122

Query: 392 CGKTFSNMTKFLYHRRTH----------AGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQ 441
           CGK F + +   +H+R H           GK+ +  +G            P         
Sbjct: 123 CGKAFGSGSNLTHHQRIHTGEKPYECKECGKAFSFGSGLIRHQIIHSGEKP--------- 173

Query: 442 LPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQ 501
             C +C KSF+  S L RH R   G  E+ + C  CGK F    ++  H R HTGE+P++
Sbjct: 174 YECKECGKSFSFESALIRHHRIHTG--EKPYECIDCGKAFGSGSNLTQHRRIHTGEKPYE 231

Query: 502 CHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPR 561
           C +CG  F+S + L+RHQ  HTG +PY C +CGK F+  S L +H+R+H           
Sbjct: 232 CKACGMAFSSGSALTRHQRIHTGEKPYICNECGKAFSFGSALTRHQRIH----------- 280

Query: 562 LPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
              TG   + PY C  CG+ F + + L  HQR+H
Sbjct: 281 ---TG---EKPYVCKECGKAFNSGSDLTQHQRIH 308



 Score =  159 bits (403), Expect = 6e-39
 Identities = 88/248 (35%), Positives = 119/248 (47%), Gaps = 47/248 (18%)

Query: 349 QHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRR 407
           QH R+H  E    C +CG+ F     LV H+R HT    + C+ CGK F +     YH+R
Sbjct: 51  QHQRIHTDEKLLECKECGKDFSFVSVLVRHQRIHTGEKPYECKECGKAFGSGANLAYHQR 110

Query: 408 THAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGP 467
            H G+             P E               C +C K+F S S L+ H+R   G 
Sbjct: 111 IHTGEK------------PFE---------------CKECGKAFGSGSNLTHHQRIHTG- 142

Query: 468 PERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARP 527
            E+ + C  CGK F     +  H   H+GE+P++C  CGK+F+  + L RH   HTG +P
Sbjct: 143 -EKPYECKECGKAFSFGSGLIRHQIIHSGEKPYECKECGKSFSFESALIRHHRIHTGEKP 201

Query: 528 YQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAG 587
           Y+C+DCGK F   SNL QHRR+H              TG   + PY C  CG  F + + 
Sbjct: 202 YECIDCGKAFGSGSNLTQHRRIH--------------TG---EKPYECKACGMAFSSGSA 244

Query: 588 LRLHQRVH 595
           L  HQR+H
Sbjct: 245 LTRHQRIH 252



 Score =  124 bits (312), Expect = 2e-28
 Identities = 95/393 (24%), Positives = 149/393 (37%), Gaps = 32/393 (8%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EAL 89
           G+A  S     +HQ        F C ECG  + +   +  HQ  H      E     +A 
Sbjct: 96  GKAFGSGANLAYHQRIHTGEKPFECKECGKAFGSGSNLTHHQRIHTGEKPYECKECGKAF 155

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
           +  +  +  +++   E P++C EC +       L+ H   H  E      Y+C DC + F
Sbjct: 156 SFGSGLIRHQIIHSGEKPYECKECGKSFSFESALIRHHRIHTGEKP----YECIDCGKAF 211

Query: 150 PSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATP 209
            S      HR+  H      E                        +PY C EC    +  
Sbjct: 212 GSGSNLTQHRRI-HTGEKPYECKACGMAFSSGSALTRHQRIHTGEKPYICNECGKAFSFG 270

Query: 210 EEFLEHQGTHFDSLE-------KEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAV 262
                HQ  H            K   +G +  +       E   E ++ E     G   +
Sbjct: 271 SALTRHQRIHTGEKPYVCKECGKAFNSGSDLTQHQRIHTGEKPYECKECEKAFRSGSKLI 330

Query: 263 GGDESTAGWAQ-GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQ 321
                  G     C +C +   S     QH R      +   P+ C +C ++F S ++L 
Sbjct: 331 QHQRMHTGEKPYECKECGKTFSSGSDLTQHHRIH----TGEKPYECKECGKAFGSGSKLI 386

Query: 322 AHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRR 380
            H   H G   +EC  C K F   ++L +H R+H GE  Y C +CG+ F +  +L  H+R
Sbjct: 387 QHQLIHTGERPYECKECGKSFSSGSALNRHQRIHTGEKPYECKECGKAFYSGSSLTQHQR 446

Query: 381 AHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGK 412
            HT   L+ C+ CGK +   ++F  H+++H GK
Sbjct: 447 IHTGEKLYECKNCGKAYGRDSEFQQHKKSHNGK 479



 Score =  105 bits (262), Expect = 1e-22
 Identities = 52/128 (40%), Positives = 70/128 (54%), Gaps = 17/128 (13%)

Query: 469 ERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPY 528
           E+   C  CGK F  +  +  H R HTGE+P++C  CGK F S ANL+ HQ  HTG +P+
Sbjct: 59  EKLLECKECGKDFSFVSVLVRHQRIHTGEKPYECKECGKAFGSGANLAYHQRIHTGEKPF 118

Query: 529 QCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGL 588
           +C +CGK F   SNL  H+R+H              TG   + PY C  CG+ F   +GL
Sbjct: 119 ECKECGKAFGSGSNLTHHQRIH--------------TG---EKPYECKECGKAFSFGSGL 161

Query: 589 RLHQRVHA 596
             HQ +H+
Sbjct: 162 IRHQIIHS 169



 Score =  102 bits (253), Expect = 1e-21
 Identities = 86/370 (23%), Positives = 137/370 (37%), Gaps = 37/370 (10%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHMLAVSEE-----EAL 89
           G+A  S     HHQ        + C ECG  ++    ++ HQ  H      E     ++ 
Sbjct: 124 GKAFGSGSNLTHHQRIHTGEKPYECKECGKAFSFGSGLIRHQIIHSGEKPYECKECGKSF 183

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
           + ++  +    +   E P++C +C +   S   L  H+  H  E      Y+C  C   F
Sbjct: 184 SFESALIRHHRIHTGEKPYECIDCGKAFGSGSNLTQHRRIHTGEKP----YECKACGMAF 239

Query: 150 PSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSE---VKMEPYECPECSTLC 206
            S      H++      T  +P +                 +      +PY C EC    
Sbjct: 240 SSGSALTRHQRIH----TGEKPYICNECGKAFSFGSALTRHQRIHTGEKPYVCKECGKAF 295

Query: 207 ATPEEFLEHQGTHFDS-------LEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGD 259
            +  +  +HQ  H           EK  R+G +  +       E   E ++       G 
Sbjct: 296 NSGSDLTQHQRIHTGEKPYECKECEKAFRSGSKLIQHQRMHTGEKPYECKECGKTFSSGS 355

Query: 260 DAVGGDESTAGWAQ-GCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSAN 318
           D         G     C +C +   S     QH+       +   P+ C +C +SFSS +
Sbjct: 356 DLTQHHRIHTGEKPYECKECGKAFGSGSKLIQHQLIH----TGERPYECKECGKSFSSGS 411

Query: 319 RLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVA 377
            L  H R H G   +EC  C K F   +SL QH R+H GE  Y C +CG+ +G +     
Sbjct: 412 ALNRHQRIHTGEKPYECKECGKAFYSGSSLTQHQRIHTGEKLYECKNCGKAYGRDSEFQQ 471

Query: 378 HRRAHTANPL 387
           H+++H    L
Sbjct: 472 HKKSHNGKKL 481


>gi|54291710 zinc finger protein 835 [Homo sapiens]
          Length = 559

 Score =  205 bits (521), Expect = 1e-52
 Identities = 113/331 (34%), Positives = 160/331 (48%), Gaps = 26/331 (7%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           C +C +    +     H+RT     +   P+ C +C ++FS  + L +H R H G   H 
Sbjct: 162 CPECGKAFSQSVHLTLHQRTH----TGEKPYACHECGKAFSQGSYLASHWRTHTGEKPHR 217

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-C 392
           C  C K F +   L QH R+H GE  Y C  C + F    +L+ H+R HT    + C  C
Sbjct: 218 CADCGKAFTRVTHLTQHRRVHTGERPYACAQCAKAFRNRSSLIEHQRIHTGEKPYECSAC 277

Query: 393 GKTFSNMTKFLYHRRTHAG-KSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSF 451
            K F   +  + H+R H   K       A A    A  T             C  C   F
Sbjct: 278 AKAFRFSSALIRHQRIHTEEKPYRCGQCAKAFAQIAHLTQHRRVHTGEKPYTCQDCGALF 337

Query: 452 ASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFAS 511
           + ++ L+ HRR   G  E+ + CG C K F ++ H+  H RTHTGERP+ CH CGK F++
Sbjct: 338 SQSASLAEHRRIHTG--EKPYACGQCAKAFTQVSHLTQHQRTHTGERPYPCHDCGKRFSN 395

Query: 512 LANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKS 571
            ++L +H+L HTG RPY+CL CG  F+  S+L +H+++H              TG   + 
Sbjct: 396 RSHLLQHRLVHTGERPYRCLQCGAAFSHVSSLIEHQKIH--------------TG---ER 438

Query: 572 PYYCGTCGRWFRAMAGLRLHQRVHARARTLT 602
           PY CG CG+ F   + L LHQR H   R  T
Sbjct: 439 PYKCGECGKAFSQGSSLALHQRTHTGERPYT 469



 Score =  199 bits (506), Expect = 7e-51
 Identities = 138/447 (30%), Positives = 184/447 (41%), Gaps = 71/447 (15%)

Query: 195 EPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAM 254
           +P+ CPEC    +       HQ TH                             E   A 
Sbjct: 158 KPFACPECGKAFSQSVHLTLHQRTHTG---------------------------EKPYAC 190

Query: 255 AEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGAR-------RQHRRTAHSPASATHPFHC 307
            E G     G    + W    G+ P      G          QHRR      +   P+ C
Sbjct: 191 HECGKAFSQGSYLASHWRTHTGEKPHRCADCGKAFTRVTHLTQHRRVH----TGERPYAC 246

Query: 308 SQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCG 366
           +QC ++F + + L  H R H G   +EC+ C+K F+ +++L +H R+H  E  Y C  C 
Sbjct: 247 AQCAKAFRNRSSLIEHQRIHTGEKPYECSACAKAFRFSSALIRHQRIHTEEKPYRCGQCA 306

Query: 367 RGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAG-KSGAPPTGATAPP 424
           + F     L  HRR HT    + C+ CG  FS       HRR H G K  A    A A  
Sbjct: 307 KAFAQIAHLTQHRRVHTGEKPYTCQDCGALFSQSASLAEHRRIHTGEKPYACGQCAKAFT 366

Query: 425 APAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKL 484
             +  T            PC  C K F++ S L +HR    G  ER +RC  CG  F  +
Sbjct: 367 QVSHLTQHQRTHTGERPYPCHDCGKRFSNRSHLLQHRLVHTG--ERPYRCLQCGAAFSHV 424

Query: 485 IHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQ 544
             +  H + HTGERP++C  CGK F+  ++L+ HQ THTG RPY C +CGK F+  S L 
Sbjct: 425 SSLIEHQKIHTGERPYKCGECGKAFSQGSSLALHQRTHTGERPYTCPECGKAFSNRSYLI 484

Query: 545 QHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARARTLTLQ 604
           QH  +H              TG   + PY C  CG+ F   + L  HQR HA        
Sbjct: 485 QHHIVH--------------TG---EKPYECSGCGKAFSFSSALIRHQRTHA-------- 519

Query: 605 PPRSPSPAPPPPPEPQQTIMCTELGET 631
                S    P P P  T   ++ GET
Sbjct: 520 ---DSSGRLCPAPTPDSTPGLSQGGET 543



 Score =  182 bits (462), Expect = 9e-46
 Identities = 128/494 (25%), Positives = 179/494 (36%), Gaps = 111/494 (22%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQLIL 118
           C +CG  ++     + HQ  H                         E PF C EC +   
Sbjct: 134 CGDCGKAFSYCSAFILHQRIHT-----------------------GEKPFACPECGKAFS 170

Query: 119 SPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPPLP 178
               L  HQ  H  E      Y C +C + F       +H +                  
Sbjct: 171 QSVHLTLHQRTHTGEK----PYACHECGKAFSQGSYLASHWRTHTGEKPHRCADCGKAFT 226

Query: 179 PPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDD 238
             T L            PY C +C+         +EHQ  H      E            
Sbjct: 227 RVTHL-TQHRRVHTGERPYACAQCAKAFRNRSSLIEHQRIHTGEKPYE------------ 273

Query: 239 EEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSP 298
                                               C  C +    + A  +H+R     
Sbjct: 274 ------------------------------------CSACAKAFRFSSALIRHQRI---- 293

Query: 299 ASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLRLHRGE 357
            +   P+ C QC ++F+    L  H R H G   + C  C  +F ++ASL +H R+H GE
Sbjct: 294 HTEEKPYRCGQCAKAFAQIAHLTQHRRVHTGEKPYTCQDCGALFSQSASLAEHRRIHTGE 353

Query: 358 ARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAP 416
             Y C  C + F     L  H+R HT    + C  CGK FSN +  L HR  H G+    
Sbjct: 354 KPYACGQCAKAFTQVSHLTQHQRTHTGERPYPCHDCGKRFSNRSHLLQHRLVHTGE---- 409

Query: 417 PTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGV 476
                                      C QC  +F+  S L  H++   G  ER ++CG 
Sbjct: 410 -----------------------RPYRCLQCGAAFSHVSSLIEHQKIHTG--ERPYKCGE 444

Query: 477 CGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKR 536
           CGK F +   +  H RTHTGERP+ C  CGK F++ + L +H + HTG +PY+C  CGK 
Sbjct: 445 CGKAFSQGSSLALHQRTHTGERPYTCPECGKAFSNRSYLIQHHIVHTGEKPYECSGCGKA 504

Query: 537 FTQSSNLQQHRRLH 550
           F+ SS L +H+R H
Sbjct: 505 FSFSSALIRHQRTH 518



 Score =  174 bits (441), Expect = 2e-43
 Identities = 123/395 (31%), Positives = 176/395 (44%), Gaps = 59/395 (14%)

Query: 222 SLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQH 281
           +L+  E  G  + E   E+ +E+ E   + EA+A  GD A              GD  Q 
Sbjct: 30  ALQGAELEGNWKHEGQVEDLQENQESCPEPEAVACKGDPA--------------GDSMQE 75

Query: 282 QPSAGARRQHRRTAHSPAS--ATHPFHCSQCQRSFSSANRLQAHG----RAHVGGTHE-- 333
           +       +  RT  SPA+  A+ P   S  + S    +  + H     R   GG  +  
Sbjct: 76  RDEFS---RIPRTISSPAATQASVPDDSSSRRCSAPGESPKERHPDSRQRERGGGPKKPW 132

Query: 334 -CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-R 391
            C  C K F   ++   H R+H GE  + C +CG+ F   + L  H+R HT    + C  
Sbjct: 133 KCGDCGKAFSYCSAFILHQRIHTGEKPFACPECGKAFSQSVHLTLHQRTHTGEKPYACHE 192

Query: 392 CGKTFSNMTKFLYHRRTHAGKS-------GAPPTGATAPPAPAEPTPPPPPPAPPAQLPC 444
           CGK FS  +    H RTH G+        G   T  T             P A      C
Sbjct: 193 CGKAFSQGSYLASHWRTHTGEKPHRCADCGKAFTRVTHLTQHRRVHTGERPYA------C 246

Query: 445 PQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHS 504
            QC+K+F + S L  H+R   G  E+ + C  C K F+    +  H R HT E+P++C  
Sbjct: 247 AQCAKAFRNRSSLIEHQRIHTG--EKPYECSACAKAFRFSSALIRHQRIHTEEKPYRCGQ 304

Query: 505 CGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPI 564
           C K FA +A+L++H+  HTG +PY C DCG  F+QS++L +HRR+H              
Sbjct: 305 CAKAFAQIAHLTQHRRVHTGEKPYTCQDCGALFSQSASLAEHRRIH-------------- 350

Query: 565 TGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           TG   + PY CG C + F  ++ L  HQR H   R
Sbjct: 351 TG---EKPYACGQCAKAFTQVSHLTQHQRTHTGER 382



 Score =  157 bits (396), Expect = 4e-38
 Identities = 119/476 (25%), Positives = 171/476 (35%), Gaps = 111/476 (23%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           F C ECG  ++    +  HQ  H                         E P+ C EC + 
Sbjct: 160 FACPECGKAFSQSVHLTLHQRTHT-----------------------GEKPYACHECGK- 195

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
             S G  LA   +H R    +  ++C DC + F        HR+                
Sbjct: 196 AFSQGSYLA---SHWRTHTGEKPHRCADCGKAFTRVTHLTQHRRV--------------- 237

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE 236
                              PY C +C+         +EHQ  H                E
Sbjct: 238 --------------HTGERPYACAQCAKAFRNRSSLIEHQRIH--------------TGE 269

Query: 237 DDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTAH 296
              E     +      A+  +    +  +E        CG C +         QHRR   
Sbjct: 270 KPYECSACAKAFRFSSAL--IRHQRIHTEEK----PYRCGQCAKAFAQIAHLTQHRRV-- 321

Query: 297 SPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLRLHR 355
              +   P+ C  C   FS +  L  H R H G   + C  C+K F + + L QH R H 
Sbjct: 322 --HTGEKPYTCQDCGALFSQSASLAEHRRIHTGEKPYACGQCAKAFTQVSHLTQHQRTHT 379

Query: 356 GEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSG 414
           GE  Y C DCG+ F     L+ HR  HT    +RC +CG  FS+++  + H++ H G+  
Sbjct: 380 GERPYPCHDCGKRFSNRSHLLQHRLVHTGERPYRCLQCGAAFSHVSSLIEHQKIHTGE-- 437

Query: 415 APPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRC 474
                                        C +C K+F+  S L+ H+R   G  ER + C
Sbjct: 438 -------------------------RPYKCGECGKAFSQGSSLALHQRTHTG--ERPYTC 470

Query: 475 GVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQC 530
             CGK F    ++  H   HTGE+P++C  CGK F+  + L RHQ TH  +    C
Sbjct: 471 PECGKAFSNRSYLIQHHIVHTGEKPYECSGCGKAFSFSSALIRHQRTHADSSGRLC 526



 Score =  118 bits (296), Expect = 2e-26
 Identities = 94/394 (23%), Positives = 141/394 (35%), Gaps = 69/394 (17%)

Query: 59  CSECGSLYNTLEEVLSHQEQHM-----LAVSEEEALTTQNVGLEPELVPGAEGPFQCGEC 113
           C++CG  +  +  +  H+  H            +A   ++  +E + +   E P++C  C
Sbjct: 218 CADCGKAFTRVTHLTQHRRVHTGERPYACAQCAKAFRNRSSLIEHQRIHTGEKPYECSAC 277

Query: 114 SQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPV 173
           ++       L+ HQ  H  E      Y+C  C + F      +AH   QH      E   
Sbjct: 278 AKAFRFSSALIRHQRIHTEEK----PYRCGQCAKAFAQ----IAH-LTQHRRVHTGE--- 325

Query: 174 PPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEE 233
                                +PY C +C  L +      EH+  H  + EK    G   
Sbjct: 326 ---------------------KPYTCQDCGALFSQSASLAEHRRIH--TGEKPYACG--- 359

Query: 234 EEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRR 293
                          +  +A  +V          T      C DC +   +     QHR 
Sbjct: 360 ---------------QCAKAFTQVSHLTQHQRTHTGERPYPCHDCGKRFSNRSHLLQHRL 404

Query: 294 TAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG-GTHECTTCSKVFKKAASLEQHLR 352
                 +   P+ C QC  +FS  + L  H + H G   ++C  C K F + +SL  H R
Sbjct: 405 V----HTGERPYRCLQCGAAFSHVSSLIEHQKIHTGERPYKCGECGKAFSQGSSLALHQR 460

Query: 353 LHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAG 411
            H GE  Y C +CG+ F     L+ H   HT    + C  CGK FS  +  + H+RTHA 
Sbjct: 461 THTGERPYTCPECGKAFSNRSYLIQHHIVHTGEKPYECSGCGKAFSFSSALIRHQRTHAD 520

Query: 412 KSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCP 445
            S     G   P    + TP         Q  CP
Sbjct: 521 SS-----GRLCPAPTPDSTPGLSQGGETCQQGCP 549


>gi|4508035 zinc finger protein 7 [Homo sapiens]
          Length = 686

 Score =  205 bits (521), Expect = 1e-52
 Identities = 120/351 (34%), Positives = 168/351 (47%), Gaps = 50/351 (14%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           C +C Q + S   + +H    H       P+ C++C + F   ++L  H R H G    +
Sbjct: 225 CQEC-QKKLSDCLQGKHTNNCHGEK----PYECAECGKVFRLCSQLNQHQRIHTGEKPFK 279

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-C 392
           CT C K F+ ++ L QH R+H GE  Y C +CG+ FG   +L+ H+R HT    + CR C
Sbjct: 280 CTECGKAFRLSSKLIQHQRIHTGEKPYRCEECGKAFGQSSSLIHHQRIHTGERPYGCREC 339

Query: 393 GKTFSNMTKFLYHRRTHAGKSGAP--------------------PTGATAPPAPAEPTPP 432
           GK FS  ++ + H+RTH G+   P                     TG  A    A  +P 
Sbjct: 340 GKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQSSTLAQHQRMHTGEKAQILKASDSPS 399

Query: 433 PPPP----APPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVR 488
                   A      C +C K+F   SRLS+H+    G  E+ ++C  C K F     + 
Sbjct: 400 LVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIHTG--EKPYKCNKCTKAFGCSSRLI 457

Query: 489 NHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRR 548
            H RTHTGE+PF+C  CGK F   ++L +HQ  HTG +PY C DCGK F+QSS+L  H+R
Sbjct: 458 RHQRTHTGEKPFKCDECGKGFVQGSHLIQHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQR 517

Query: 549 LHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           +H                   + PY C  CG+ F     L +HQRVH   R
Sbjct: 518 IH-----------------KGEKPYECLQCGKAFSMSTQLTIHQRVHTGER 551



 Score =  197 bits (500), Expect = 3e-50
 Identities = 118/362 (32%), Positives = 174/362 (48%), Gaps = 43/362 (11%)

Query: 275 CGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HE 333
           C +C +         QH+R      +   PF C++C ++F  +++L  H R H G   + 
Sbjct: 252 CAECGKVFRLCSQLNQHQRIH----TGEKPFKCTECGKAFRLSSKLIQHQRIHTGEKPYR 307

Query: 334 CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-C 392
           C  C K F +++SL  H R+H GE  Y C +CG+ F  +  LV H+R HT    + C+ C
Sbjct: 308 CEECGKAFGQSSSLIHHQRIHTGERPYGCRECGKAFSQQSQLVRHQRTHTGERPYPCKEC 367

Query: 393 GKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPT------PPPPPPAPPA------ 440
           GK FS  +    H+R H G+       + +P   A         P        A      
Sbjct: 368 GKAFSQSSTLAQHQRMHTGEKAQILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISR 427

Query: 441 ------------QLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVR 488
                          C +C+K+F  +SRL RH+R   G  E+  +C  CGKGF +  H+ 
Sbjct: 428 LSQHQLIHTGEKPYKCNKCTKAFGCSSRLIRHQRTHTG--EKPFKCDECGKGFVQGSHLI 485

Query: 489 NHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRR 548
            H R HTGE+P+ C+ CGK F+  ++L  HQ  H G +PY+CL CGK F+ S+ L  H+R
Sbjct: 486 QHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQRIHKGEKPYECLQCGKAFSMSTQLTIHQR 545

Query: 549 LHL--RPV-------AFARAPRLPITGLYNK--SPYYCGTCGRWFRAMAGLRLHQRVHAR 597
           +H   RP        AF++   L    + +    PY C  CG+ F   + L  HQR+H R
Sbjct: 546 VHTGERPYKCNECGKAFSQNSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTR 605

Query: 598 AR 599
           A+
Sbjct: 606 AQ 607



 Score =  187 bits (474), Expect = 4e-47
 Identities = 139/576 (24%), Positives = 212/576 (36%), Gaps = 156/576 (27%)

Query: 59  CSECGSLYNTLEEVLSHQEQHMLAVSE----EEALTTQNVGLEPELVPGAEGPFQCGECS 114
           C ECG       ++  H E +   +S     ++ L+    G       G E P++C EC 
Sbjct: 198 CEECGKGIRATSDIALHWEINTQKISRCQECQKKLSDCLQGKHTNNCHG-EKPYECAECG 256

Query: 115 QLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVP 174
           ++     +L  HQ  H  E      ++C +C + F      ++ +  QH      E    
Sbjct: 257 KVFRLCSQLNQHQRIHTGEKP----FKCTECGKAFR-----LSSKLIQHQRIHTGE---- 303

Query: 175 PPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEE 234
                               +PY C EC          + HQ  H               
Sbjct: 304 --------------------KPYRCEECGKAFGQSSSLIHHQRIH--------------- 328

Query: 235 EEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRT 294
                                            T     GC +C +         +H+RT
Sbjct: 329 ---------------------------------TGERPYGCRECGKAFSQQSQLVRHQRT 355

Query: 295 AHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHE--------------------- 333
                +   P+ C +C ++FS ++ L  H R H G   +                     
Sbjct: 356 H----TGERPYPCKECGKAFSQSSTLAQHQRMHTGEKAQILKASDSPSLVAHQRIHAVEK 411

Query: 334 ---CTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC 390
              C  C K F+  + L QH  +H GE  Y C  C + FG    L+ H+R HT     +C
Sbjct: 412 PFKCDECGKAFRWISRLSQHQLIHTGEKPYKCNKCTKAFGCSSRLIRHQRTHTGEKPFKC 471

Query: 391 -RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSK 449
             CGK F   +  + H+R H G+                               C  C K
Sbjct: 472 DECGKGFVQGSHLIQHQRIHTGEK---------------------------PYVCNDCGK 504

Query: 450 SFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTF 509
           +F+ +S L  H+R   G  E+ + C  CGK F     +  H R HTGERP++C+ CGK F
Sbjct: 505 AFSQSSSLIYHQRIHKG--EKPYECLQCGKAFSMSTQLTIHQRVHTGERPYKCNECGKAF 562

Query: 510 ASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFAR----------A 559
           +  + L +HQ+ H G +PY+C +CGK F++SS L +H+R+H R   F             
Sbjct: 563 SQNSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALEGSTFV 622

Query: 560 PRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
            R  +  +  K  + C  C + FR  + L +HQR+H
Sbjct: 623 SRKKVNTI--KKLHQCEDCEKIFRWRSHLIIHQRIH 656



 Score =  172 bits (435), Expect = 1e-42
 Identities = 126/529 (23%), Positives = 199/529 (37%), Gaps = 127/529 (24%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           + C+ECG ++    ++  HQ  H                         E PF+C EC + 
Sbjct: 250 YECAECGKVFRLCSQLNQHQRIHT-----------------------GEKPFKCTECGKA 286

Query: 117 ILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEPPVPPP 176
                +L+ HQ  H  E      Y+C +C + F      + H++                
Sbjct: 287 FRLSSKLIQHQRIHTGEKP----YRCEECGKAFGQSSSLIHHQRIH-------------- 328

Query: 177 LPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLE---KEERNGLEE 233
                              PY C EC    +   + + HQ TH        KE      +
Sbjct: 329 ---------------TGERPYGCRECGKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQ 373

Query: 234 EEEDDEEDE----EDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARR 289
                +       E  + ++  ++ + V    +   E        C +C +         
Sbjct: 374 SSTLAQHQRMHTGEKAQILKASDSPSLVAHQRIHAVEKPFK----CDECGKAFRWISRLS 429

Query: 290 QHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLE 348
           QH+       +   P+ C++C ++F  ++RL  H R H G    +C  C K F + + L 
Sbjct: 430 QHQLIH----TGEKPYKCNKCTKAFGCSSRLIRHQRTHTGEKPFKCDECGKGFVQGSHLI 485

Query: 349 QHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRR 407
           QH R+H GE  Y+C DCG+ F    +L+ H+R H     + C +CGK FS  T+   H+R
Sbjct: 486 QHQRIHTGEKPYVCNDCGKAFSQSSSLIYHQRIHKGEKPYECLQCGKAFSMSTQLTIHQR 545

Query: 408 THAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGP 467
            H G+                               C +C K+F+  S L +H+    G 
Sbjct: 546 VHTGER---------------------------PYKCNECGKAFSQNSTLFQHQIIHAGV 578

Query: 468 PERRHRCGVCGKGFKKLIHVRNHLRTHTGERPF-------------------------QC 502
             + + C  CGK F +  ++  H R HT  + F                         QC
Sbjct: 579 --KPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALEGSTFVSRKKVNTIKKLHQC 636

Query: 503 HSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHL 551
             C K F   ++L  HQ  HTG +PY+C DCGK F +SS L QH+++H+
Sbjct: 637 EDCEKIFRWRSHLIIHQRIHTGEKPYKCNDCGKAFNRSSRLTQHQKIHM 685



 Score =  150 bits (379), Expect = 4e-36
 Identities = 89/298 (29%), Positives = 132/298 (44%), Gaps = 36/298 (12%)

Query: 304 PFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCV 363
           P  C +   S      L++ G +  G +  C  C K  +  + +  H  ++  +    C 
Sbjct: 168 PQGCKELGSSGLDCQPLESQGESAEGMSQRCEECGKGIRATSDIALHWEINTQKISR-CQ 226

Query: 364 DCGRGFGTELTLVAHRRAHTANPLHRCRCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAP 423
           +C +     L        H   P     CGK F   ++   H+R H G+           
Sbjct: 227 ECQKKLSDCLQGKHTNNCHGEKPYECAECGKVFRLCSQLNQHQRIHTGEK---------- 276

Query: 424 PAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKK 483
                               C +C K+F  +S+L +H+R   G  E+ +RC  CGK F +
Sbjct: 277 -----------------PFKCTECGKAFRLSSKLIQHQRIHTG--EKPYRCEECGKAFGQ 317

Query: 484 LIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNL 543
              + +H R HTGERP+ C  CGK F+  + L RHQ THTG RPY C +CGK F+QSS L
Sbjct: 318 SSSLIHHQRIHTGERPYGCRECGKAFSQQSQLVRHQRTHTGERPYPCKECGKAFSQSSTL 377

Query: 544 QQHRRLHLRPVA-FARAPRLPITGLYNK-----SPYYCGTCGRWFRAMAGLRLHQRVH 595
            QH+R+H    A   +A   P    + +      P+ C  CG+ FR ++ L  HQ +H
Sbjct: 378 AQHQRMHTGEKAQILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIH 435



 Score =  134 bits (336), Expect = 4e-31
 Identities = 118/501 (23%), Positives = 181/501 (36%), Gaps = 125/501 (24%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVG---------LEPELVPGAEGP 107
           F C+ECG  +    +++ HQ  H    + E+    +  G         +  + +   E P
Sbjct: 278 FKCTECGKAFRLSSKLIQHQRIH----TGEKPYRCEECGKAFGQSSSLIHHQRIHTGERP 333

Query: 108 FQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHR------KA 161
           + C EC +      +L+ HQ  H  E      Y C +C + F        H+      KA
Sbjct: 334 YGCRECGKAFSQQSQLVRHQRTHTGERP----YPCKECGKAFSQSSTLAQHQRMHTGEKA 389

Query: 162 QHLSATVAEPPVPPPLPPPTPLPPP-----------SPPSEVKM-----EPYECPECSTL 205
           Q L A+ +   V          P             S  S+ ++     +PY+C +C+  
Sbjct: 390 QILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIHTGEKPYKCNKCTKA 449

Query: 206 CATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGD 265
                  + HQ TH                                      G+     D
Sbjct: 450 FGCSSRLIRHQRTH-------------------------------------TGEKPFKCD 472

Query: 266 ESTAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGR 325
           E   G+ QG     QHQ      R H        +   P+ C+ C ++FS ++ L  H R
Sbjct: 473 ECGKGFVQG-SHLIQHQ------RIH--------TGEKPYVCNDCGKAFSQSSSLIYHQR 517

Query: 326 AHVG-GTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTA 384
            H G   +EC  C K F  +  L  H R+H GE  Y C +CG+ F    TL  H+  H  
Sbjct: 518 IHKGEKPYECLQCGKAFSMSTQLTIHQRVHTGERPYKCNECGKAFSQNSTLFQHQIIHAG 577

Query: 385 NPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLP 443
              + C  CGK FS  +  + H+R H         G                        
Sbjct: 578 VKPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALE-------------------- 617

Query: 444 CPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCH 503
                 +F S  +++  ++         H+C  C K F+   H+  H R HTGE+P++C+
Sbjct: 618 ----GSTFVSRKKVNTIKKL--------HQCEDCEKIFRWRSHLIIHQRIHTGEKPYKCN 665

Query: 504 SCGKTFASLANLSRHQLTHTG 524
            CGK F   + L++HQ  H G
Sbjct: 666 DCGKAFNRSSRLTQHQKIHMG 686



 Score =  126 bits (317), Expect = 6e-29
 Identities = 79/250 (31%), Positives = 112/250 (44%), Gaps = 49/250 (19%)

Query: 362 CVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAPPTGA 420
           C +CG+G      +  H   +T   + RC+ C K  S+  +  +    H  K        
Sbjct: 198 CEECGKGIRATSDIALHWEINTQK-ISRCQECQKKLSDCLQGKHTNNCHGEK-------- 248

Query: 421 TAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKG 480
                P E               C +C K F   S+L++H+R   G  E+  +C  CGK 
Sbjct: 249 -----PYE---------------CAECGKVFRLCSQLNQHQRIHTG--EKPFKCTECGKA 286

Query: 481 FKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQS 540
           F+    +  H R HTGE+P++C  CGK F   ++L  HQ  HTG RPY C +CGK F+Q 
Sbjct: 287 FRLSSKLIQHQRIHTGEKPYRCEECGKAFGQSSSLIHHQRIHTGERPYGCRECGKAFSQQ 346

Query: 541 SNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARART 600
           S L +H+R H              TG   + PY C  CG+ F   + L  HQR+H   + 
Sbjct: 347 SQLVRHQRTH--------------TG---ERPYPCKECGKAFSQSSTLAQHQRMHTGEKA 389

Query: 601 LTLQPPRSPS 610
             L+   SPS
Sbjct: 390 QILKASDSPS 399



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 32/152 (21%), Positives = 60/152 (39%), Gaps = 34/152 (22%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHM----LAVSEEEALT 90
           G+A + S    +HQ        + C +CG  ++   ++  HQ  H        +E     
Sbjct: 503 GKAFSQSSSLIYHQRIHKGEKPYECLQCGKAFSMSTQLTIHQRVHTGERPYKCNECGKAF 562

Query: 91  TQNVGL-EPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLR-----ESANQIQ----- 139
           +QN  L + +++     P++C EC +       L+ HQ  H R     E  N ++     
Sbjct: 563 SQNSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALEGSTFV 622

Query: 140 -----------YQCWDCQELFPSPELWVAHRK 160
                      +QC DC+++F      + H++
Sbjct: 623 SRKKVNTIKKLHQCEDCEKIFRWRSHLIIHQR 654



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 30/122 (24%), Positives = 47/122 (38%), Gaps = 13/122 (10%)

Query: 48  SSLFFQHH-------QFMCSECGSLYNTLEEVLSHQEQHMLA--VSEEEALTTQNVGLEP 98
           +S  FQH         + CSECG  ++    ++ HQ  H  A    E       +  +  
Sbjct: 565 NSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTRAQWFYEYGNALEGSTFVSR 624

Query: 99  ELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAH 158
           + V   +   QC +C ++      L+ HQ  H  E      Y+C DC + F        H
Sbjct: 625 KKVNTIKKLHQCEDCEKIFRWRSHLIIHQRIHTGEKP----YKCNDCGKAFNRSSRLTQH 680

Query: 159 RK 160
           +K
Sbjct: 681 QK 682


>gi|110349775 zinc finger protein 12 isoform b [Homo sapiens]
          Length = 659

 Score =  204 bits (519), Expect = 2e-52
 Identities = 151/568 (26%), Positives = 220/568 (38%), Gaps = 100/568 (17%)

Query: 44  EALASSLFFQHHQFMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPG 103
           E+L   +      F   EC   +      ++H E+     +  E    Q   L       
Sbjct: 166 ESLYQKIRILEKPFEYIECQKAFQKDTVFVNHMEEKPYKWNGSEIAFLQMSDLTVHQTSH 225

Query: 104 AE-GPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQ 162
            E  P++C EC +      + + HQ  H  E      Y+C  C + F        H++  
Sbjct: 226 MEMKPYECSECGKSFCKKSKFIIHQRTHTGEKP----YECNQCGKSFCQKGTLTVHQR-- 279

Query: 163 HLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDS 222
                                      +    +PYEC EC          ++HQ TH  S
Sbjct: 280 ---------------------------THTGEKPYECNECGKNFYQKLHLIQHQRTH--S 310

Query: 223 LEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQ 282
            EK        +    +      +     E                      C DC +  
Sbjct: 311 GEKPYECSYCGKSFCQKTHLTQHQRTHSGER------------------PYVCHDCGKTF 352

Query: 283 PSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVF 341
               A   H++      +    + CS+C + F   + L  H R H G   +EC  C K F
Sbjct: 353 SQKSALNDHQKIH----TGVKLYKCSECGKCFCRKSTLTTHLRTHTGEKPYECNECGKFF 408

Query: 342 KKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMT 400
            + + L  H R H GE  Y C +CG+ F     L+ H+R HT    + C  CGK FS ++
Sbjct: 409 SRLSYLTVHYRTHSGEKPYECNECGKTFYLNSALMRHQRVHTGEKPYECNECGKLFSQLS 468

Query: 401 KFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRH 460
               H RTH+G              P E               C +C K+F   S L RH
Sbjct: 469 YLTIHHRTHSGVK------------PYE---------------CSECGKTFYQNSALCRH 501

Query: 461 RRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQL 520
           RR   G  E+ + C +CGK F ++ ++  H R H+GE+P++C  CGKTF   + L+RHQ 
Sbjct: 502 RRIHKG--EKPYECYICGKFFSQMSYLTIHHRIHSGEKPYECSECGKTFCQNSALNRHQR 559

Query: 521 THTGARPYQCLDCGKRFTQSSNLQQHRRLHL--RPV-------AFARAPRLPI--TGLYN 569
           THTG + Y+C +CGK F+Q S L  H R+H   +P        AF+R   L +       
Sbjct: 560 THTGEKAYECYECGKCFSQMSYLTIHHRIHSGEKPFECNECGKAFSRMSYLTVHYRTHSG 619

Query: 570 KSPYYCGTCGRWFRAMAGLRLHQRVHAR 597
           + PY C  CG+ F   +    HQR+H R
Sbjct: 620 EKPYECTECGKKFYHKSAFNSHQRIHRR 647



 Score =  106 bits (264), Expect = 8e-23
 Identities = 51/128 (39%), Positives = 66/128 (51%), Gaps = 17/128 (13%)

Query: 472 HRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCL 531
           + C  CGK F K      H RTHTGE+P++C+ CGK+F     L+ HQ THTG +PY+C 
Sbjct: 231 YECSECGKSFCKKSKFIIHQRTHTGEKPYECNQCGKSFCQKGTLTVHQRTHTGEKPYECN 290

Query: 532 DCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLH 591
           +CGK F Q  +L QH+R H                   + PY C  CG+ F     L  H
Sbjct: 291 ECGKNFYQKLHLIQHQRTH-----------------SGEKPYECSYCGKSFCQKTHLTQH 333

Query: 592 QRVHARAR 599
           QR H+  R
Sbjct: 334 QRTHSGER 341



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 18/82 (21%), Positives = 28/82 (34%), Gaps = 23/82 (28%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           F C+ECG  ++ +  +  H   H                         E P++C EC + 
Sbjct: 595 FECNECGKAFSRMSYLTVHYRTH-----------------------SGEKPYECTECGKK 631

Query: 117 ILSPGELLAHQDAHLRESANQI 138
                   +HQ  H R + N I
Sbjct: 632 FYHKSAFNSHQRIHRRGNMNVI 653


>gi|66348108 zinc finger protein 12 isoform a [Homo sapiens]
          Length = 697

 Score =  204 bits (519), Expect = 2e-52
 Identities = 151/568 (26%), Positives = 220/568 (38%), Gaps = 100/568 (17%)

Query: 44  EALASSLFFQHHQFMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPG 103
           E+L   +      F   EC   +      ++H E+     +  E    Q   L       
Sbjct: 204 ESLYQKIRILEKPFEYIECQKAFQKDTVFVNHMEEKPYKWNGSEIAFLQMSDLTVHQTSH 263

Query: 104 AE-GPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELFPSPELWVAHRKAQ 162
            E  P++C EC +      + + HQ  H  E      Y+C  C + F        H++  
Sbjct: 264 MEMKPYECSECGKSFCKKSKFIIHQRTHTGEKP----YECNQCGKSFCQKGTLTVHQR-- 317

Query: 163 HLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDS 222
                                      +    +PYEC EC          ++HQ TH  S
Sbjct: 318 ---------------------------THTGEKPYECNECGKNFYQKLHLIQHQRTH--S 348

Query: 223 LEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQ 282
            EK        +    +      +     E                      C DC +  
Sbjct: 349 GEKPYECSYCGKSFCQKTHLTQHQRTHSGER------------------PYVCHDCGKTF 390

Query: 283 PSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVF 341
               A   H++      +    + CS+C + F   + L  H R H G   +EC  C K F
Sbjct: 391 SQKSALNDHQKIH----TGVKLYKCSECGKCFCRKSTLTTHLRTHTGEKPYECNECGKFF 446

Query: 342 KKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMT 400
            + + L  H R H GE  Y C +CG+ F     L+ H+R HT    + C  CGK FS ++
Sbjct: 447 SRLSYLTVHYRTHSGEKPYECNECGKTFYLNSALMRHQRVHTGEKPYECNECGKLFSQLS 506

Query: 401 KFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRH 460
               H RTH+G              P E               C +C K+F   S L RH
Sbjct: 507 YLTIHHRTHSGVK------------PYE---------------CSECGKTFYQNSALCRH 539

Query: 461 RRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQL 520
           RR   G  E+ + C +CGK F ++ ++  H R H+GE+P++C  CGKTF   + L+RHQ 
Sbjct: 540 RRIHKG--EKPYECYICGKFFSQMSYLTIHHRIHSGEKPYECSECGKTFCQNSALNRHQR 597

Query: 521 THTGARPYQCLDCGKRFTQSSNLQQHRRLHL--RPV-------AFARAPRLPI--TGLYN 569
           THTG + Y+C +CGK F+Q S L  H R+H   +P        AF+R   L +       
Sbjct: 598 THTGEKAYECYECGKCFSQMSYLTIHHRIHSGEKPFECNECGKAFSRMSYLTVHYRTHSG 657

Query: 570 KSPYYCGTCGRWFRAMAGLRLHQRVHAR 597
           + PY C  CG+ F   +    HQR+H R
Sbjct: 658 EKPYECTECGKKFYHKSAFNSHQRIHRR 685



 Score =  106 bits (264), Expect = 8e-23
 Identities = 51/128 (39%), Positives = 66/128 (51%), Gaps = 17/128 (13%)

Query: 472 HRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCL 531
           + C  CGK F K      H RTHTGE+P++C+ CGK+F     L+ HQ THTG +PY+C 
Sbjct: 269 YECSECGKSFCKKSKFIIHQRTHTGEKPYECNQCGKSFCQKGTLTVHQRTHTGEKPYECN 328

Query: 532 DCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLH 591
           +CGK F Q  +L QH+R H                   + PY C  CG+ F     L  H
Sbjct: 329 ECGKNFYQKLHLIQHQRTH-----------------SGEKPYECSYCGKSFCQKTHLTQH 371

Query: 592 QRVHARAR 599
           QR H+  R
Sbjct: 372 QRTHSGER 379



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 18/82 (21%), Positives = 28/82 (34%), Gaps = 23/82 (28%)

Query: 57  FMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPGAEGPFQCGECSQL 116
           F C+ECG  ++ +  +  H   H                         E P++C EC + 
Sbjct: 633 FECNECGKAFSRMSYLTVHYRTH-----------------------SGEKPYECTECGKK 669

Query: 117 ILSPGELLAHQDAHLRESANQI 138
                   +HQ  H R + N I
Sbjct: 670 FYHKSAFNSHQRIHRRGNMNVI 691


>gi|149192841 zinc finger protein 527 [Homo sapiens]
          Length = 609

 Score =  203 bits (517), Expect = 4e-52
 Identities = 128/424 (30%), Positives = 190/424 (44%), Gaps = 71/424 (16%)

Query: 188 PPSEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEE---------DD 238
           PP E   +PYE  + S L +    F +HQ THF  L     +G +E  +           
Sbjct: 240 PPGE---KPYESHDFSKLLSFHSLFTQHQTTHFGKLP----HGYDECGDAFSCYSFFTQP 292

Query: 239 EEDEEDDEEMEDEEAMAEVGDDAVGGDESTAGWAQG---CGDCPQHQPSAGARRQHRRTA 295
           +     ++     +       D    +       +    C +C +    +    QH+R  
Sbjct: 293 QRIHSGEKPYACNDCGKAFSHDFFLSEHQRTHIGEKPYECKECNKAFRQSAHLAQHQRIH 352

Query: 296 HSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLH 354
               +   PF C++C ++FS    L  H R H G   +EC  C+K F+++A L QH R+H
Sbjct: 353 ----TGEKPFACNECGKAFSRYAFLVEHQRIHTGEKPYECKECNKAFRQSAHLNQHQRIH 408

Query: 355 RGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKS 413
            GE  Y C  CG+ F   + L  H+R HT     +C  CGKTF   +    H+R H G+ 
Sbjct: 409 TGEKPYECNQCGKAFSRRIALTLHQRIHTGEKPFKCSECGKTFGYRSHLNQHQRIHTGEK 468

Query: 414 GAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHR 473
                       P E               C +C K F + S+L+RH R   G  ER   
Sbjct: 469 ------------PYE---------------CIKCGKFFRTDSQLNRHHRIHTG--ERPFE 499

Query: 474 CGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDC 533
           C  CGK F   + + +H R+H GE+P++C+ CGK F+  + L++HQ  HTG +PY+C +C
Sbjct: 500 CSKCGKAFSDALVLIHHKRSHAGEKPYECNKCGKAFSCGSYLNQHQRIHTGEKPYECSEC 559

Query: 534 GKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQR 593
           GK F Q  +L+ H+R+H                   + PY C  CG  F  ++ LR HQR
Sbjct: 560 GKAFHQILSLRLHQRIHA-----------------GEKPYKCNECGNNFSCVSALRRHQR 602

Query: 594 VHAR 597
           +H R
Sbjct: 603 IHNR 606



 Score =  159 bits (402), Expect = 8e-39
 Identities = 89/298 (29%), Positives = 129/298 (43%), Gaps = 48/298 (16%)

Query: 304 PFHCSQCQRSFSSANRLQAHGRAHVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLC 362
           P+      +  S  +    H   H G   H    C   F   +   Q  R+H GE  Y C
Sbjct: 245 PYESHDFSKLLSFHSLFTQHQTTHFGKLPHGYDECGDAFSCYSFFTQPQRIHSGEKPYAC 304

Query: 363 VDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAPPTGAT 421
            DCG+ F  +  L  H+R H     + C+ C K F        H+R H G+         
Sbjct: 305 NDCGKAFSHDFFLSEHQRTHIGEKPYECKECNKAFRQSAHLAQHQRIHTGEK-------- 356

Query: 422 APPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGF 481
                                 C +C K+F+  + L  H+R   G  E+ + C  C K F
Sbjct: 357 -------------------PFACNECGKAFSRYAFLVEHQRIHTG--EKPYECKECNKAF 395

Query: 482 KKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSS 541
           ++  H+  H R HTGE+P++C+ CGK F+    L+ HQ  HTG +P++C +CGK F   S
Sbjct: 396 RQSAHLNQHQRIHTGEKPYECNQCGKAFSRRIALTLHQRIHTGEKPFKCSECGKTFGYRS 455

Query: 542 NLQQHRRLHLRPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARAR 599
           +L QH+R+H              TG   + PY C  CG++FR  + L  H R+H   R
Sbjct: 456 HLNQHQRIH--------------TG---EKPYECIKCGKFFRTDSQLNRHHRIHTGER 496



 Score =  133 bits (334), Expect = 6e-31
 Identities = 85/278 (30%), Positives = 121/278 (43%), Gaps = 53/278 (19%)

Query: 319 RLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAH 378
           RL A   + +G  +EC    + F ++  L + + +  GE  Y   D  +          H
Sbjct: 211 RLHAEKESLIG--NEC----EEFNQSTYLSKDIGIPPGEKPYESHDFSKLLSFHSLFTQH 264

Query: 379 RRAHTANPLHRC-RCGKTFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPA 437
           +  H     H    CG  FS  + F   +R H+G+                         
Sbjct: 265 QTTHFGKLPHGYDECGDAFSCYSFFTQPQRIHSGEK------------------------ 300

Query: 438 PPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGE 497
                 C  C K+F+    LS H+R   G  E+ + C  C K F++  H+  H R HTGE
Sbjct: 301 ---PYACNDCGKAFSHDFFLSEHQRTHIG--EKPYECKECNKAFRQSAHLAQHQRIHTGE 355

Query: 498 RPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFA 557
           +PF C+ CGK F+  A L  HQ  HTG +PY+C +C K F QS++L QH+R+H       
Sbjct: 356 KPFACNECGKAFSRYAFLVEHQRIHTGEKPYECKECNKAFRQSAHLNQHQRIH------- 408

Query: 558 RAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVH 595
                  TG   + PY C  CG+ F     L LHQR+H
Sbjct: 409 -------TG---EKPYECNQCGKAFSRRIALTLHQRIH 436



 Score =  119 bits (298), Expect = 9e-27
 Identities = 101/421 (23%), Positives = 150/421 (35%), Gaps = 104/421 (24%)

Query: 87  EALTTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQ 146
           +A +  +   +P+ +   E P+ C +C +       L  HQ  H+ E      Y+C +C 
Sbjct: 281 DAFSCYSFFTQPQRIHSGEKPYACNDCGKAFSHDFFLSEHQRTHIGEKP----YECKECN 336

Query: 147 ELFPSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLC 206
           + F       AH  AQH      E                        +P+ C EC    
Sbjct: 337 KAFRQS----AHL-AQHQRIHTGE------------------------KPFACNECGKAF 367

Query: 207 ATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDE 266
           +     +EHQ  H      E                                        
Sbjct: 368 SRYAFLVEHQRIHTGEKPYE---------------------------------------- 387

Query: 267 STAGWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRA 326
                   C +C +    +    QH+R      +   P+ C+QC ++FS    L  H R 
Sbjct: 388 --------CKECNKAFRQSAHLNQHQRIH----TGEKPYECNQCGKAFSRRIALTLHQRI 435

Query: 327 HVGGT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTAN 385
           H G    +C+ C K F   + L QH R+H GE  Y C+ CG+ F T+  L  H R HT  
Sbjct: 436 HTGEKPFKCSECGKTFGYRSHLNQHQRIHTGEKPYECIKCGKFFRTDSQLNRHHRIHTGE 495

Query: 386 PLHRC-RCGKTFSNMTKFLYHRRTHAGKSG--------APPTGATAPPAPAEPTPPPPPP 436
               C +CGK FS+    ++H+R+HAG+          A   G+         T   P  
Sbjct: 496 RPFECSKCGKAFSDALVLIHHKRSHAGEKPYECNKCGKAFSCGSYLNQHQRIHTGEKP-- 553

Query: 437 APPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTG 496
                  C +C K+F     L  H+R   G  E+ ++C  CG  F  +  +R H R H  
Sbjct: 554 -----YECSECGKAFHQILSLRLHQRIHAG--EKPYKCNECGNNFSCVSALRRHQRIHNR 606

Query: 497 E 497
           E
Sbjct: 607 E 607



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 78/359 (21%), Positives = 121/359 (33%), Gaps = 71/359 (19%)

Query: 43  GEALASSLFFQHHQ--------FMCSECGSLYNTLEEVLSHQEQHM----LAVSE-EEAL 89
           G+A +   F   HQ        + C EC   +     +  HQ  H      A +E  +A 
Sbjct: 308 GKAFSHDFFLSEHQRTHIGEKPYECKECNKAFRQSAHLAQHQRIHTGEKPFACNECGKAF 367

Query: 90  TTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQELF 149
           +     +E + +   E P++C EC++       L  HQ  H  E      Y+C  C + F
Sbjct: 368 SRYAFLVEHQRIHTGEKPYECKECNKAFRQSAHLNQHQRIHTGEKP----YECNQCGKAF 423

Query: 150 PSPELWVAHRKAQHLSATVAEPPVPPPLPPPTPLPPPSPPSEVKMEPYECPECSTLCATP 209
                   H++                                  +P++C EC       
Sbjct: 424 SRRIALTLHQRIH-----------------------------TGEKPFKCSECGKTFGYR 454

Query: 210 EEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEMEDEEAMAEVGDDAVGGDESTA 269
               +HQ  H      E     +    D + +      +   E   E             
Sbjct: 455 SHLNQHQRIHTGEKPYECIKCGKFFRTDSQLNRH--HRIHTGERPFE------------- 499

Query: 270 GWAQGCGDCPQHQPSAGARRQHRRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVG 329
                C  C +    A     H+R+     +   P+ C++C ++FS  + L  H R H G
Sbjct: 500 -----CSKCGKAFSDALVLIHHKRSH----AGEKPYECNKCGKAFSCGSYLNQHQRIHTG 550

Query: 330 GT-HECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPL 387
              +EC+ C K F +  SL  H R+H GE  Y C +CG  F     L  H+R H    L
Sbjct: 551 EKPYECSECGKAFHQILSLRLHQRIHAGEKPYKCNECGNNFSCVSALRRHQRIHNRETL 609



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 26/122 (21%), Positives = 42/122 (34%), Gaps = 41/122 (33%)

Query: 42  PGEALASSLFFQ-------HHQ-------FMCSECGSLYNTLEEVLSHQEQHMLAVSEEE 87
           P E +    FF+       HH+       F CS+CG  ++    ++ H+  H        
Sbjct: 469 PYECIKCGKFFRTDSQLNRHHRIHTGERPFECSKCGKAFSDALVLIHHKRSH-------- 520

Query: 88  ALTTQNVGLEPELVPGAEGPFQCGECSQLILSPGELLAHQDAHLRESANQIQYQCWDCQE 147
                            E P++C +C +       L  HQ  H  E      Y+C +C +
Sbjct: 521 ---------------AGEKPYECNKCGKAFSCGSYLNQHQRIHTGEK----PYECSECGK 561

Query: 148 LF 149
            F
Sbjct: 562 AF 563


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.131    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,179,290
Number of Sequences: 37866
Number of extensions: 2382801
Number of successful extensions: 172329
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2137
Number of HSP's successfully gapped in prelim test: 704
Number of HSP's that attempted gapping in prelim test: 35836
Number of HSP's gapped (non-prelim): 58780
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.