Search of human proteins with 4507741

Search of human proteins with 4507741

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507741 twist [Homo sapiens]
         (202 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507741 twist [Homo sapiens]                                       406   e-114
gi|17981708 twist homolog 2 [Homo sapiens]                            231   2e-61
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    87   1e-17
gi|116805332 musculin [Homo sapiens]                                   82   4e-16
gi|148922889 scleraxis homolog B [Homo sapiens]                        77   8e-15
gi|186972126 scleraxis homolog A [Homo sapiens]                        77   8e-15
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo...    77   1e-14
gi|30039710 pancreas specific transcription factor, 1a [Homo sap...    75   3e-14
gi|31077092 neurogenin 2 [Homo sapiens]                                71   7e-13
gi|5031943 nescient helix loop helix 1 [Homo sapiens]                  70   1e-12
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    67   8e-12
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]          67   1e-11
gi|239749439 PREDICTED: similar to transcription factor 23 [Homo...    65   5e-11
gi|239743573 PREDICTED: similar to transcription factor 23 [Homo...    65   5e-11
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi...    65   5e-11
gi|38202237 transcription factor 21 [Homo sapiens]                     64   9e-11
gi|38202239 transcription factor 21 [Homo sapiens]                     64   9e-11
gi|195972866 keratin 10 [Homo sapiens]                                 64   1e-10
gi|239754900 PREDICTED: similar to transcription factor 23 [Homo...    62   3e-10
gi|55956899 keratin 9 [Homo sapiens]                                   62   4e-10
gi|4758506 basic helix-loop-helix transcription factor HAND1 [Ho...    60   1e-09
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]          60   1e-09
gi|109452587 family with sequence similarity 98, member B isofor...    60   2e-09
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi...    59   4e-09
gi|23097242 nephew of atonal 3 [Homo sapiens]                          58   6e-09
gi|4885075 atonal homolog 1 [Homo sapiens]                             57   8e-09
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]     57   8e-09
gi|68989258 neurogenin 3 [Homo sapiens]                                57   1e-08
gi|21553337 atonal homolog 7 [Homo sapiens]                            57   1e-08
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    56   2e-08

>gi|4507741 twist [Homo sapiens]
          Length = 202

 Score =  406 bits (1043), Expect = e-114
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 1   MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV 60
           MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV
Sbjct: 1   MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGV 60

Query: 61  GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR 120
           GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR
Sbjct: 61  GGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQR 120

Query: 121 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH 180
           TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH
Sbjct: 121 TQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH 180

Query: 181 ERLSYAFSVWRMEGAWSMSASH 202
           ERLSYAFSVWRMEGAWSMSASH
Sbjct: 181 ERLSYAFSVWRMEGAWSMSASH 202


>gi|17981708 twist homolog 2 [Homo sapiens]
          Length = 160

 Score =  231 bits (590), Expect = 2e-61
 Identities = 133/201 (66%), Positives = 145/201 (72%), Gaps = 41/201 (20%)

Query: 2   MQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVG 61
           M++ SSSPVSP D SL  SEEE +RQ     KR GRKRR S++S+               
Sbjct: 1   MEEGSSSPVSPVD-SLGTSEEELERQP----KRFGRKRRYSKKSS--------------- 40

Query: 62  GGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRT 121
              E GSP  GKRGKK                  G  S QS+EELQ+QR++ANVRERQRT
Sbjct: 41  ---EDGSPTPGKRGKK------------------GSPSAQSFEELQSQRILANVRERQRT 79

Query: 122 QSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHE 181
           QSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDE+D+KM SCSYVAHE
Sbjct: 80  QSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDEMDNKMTSCSYVAHE 139

Query: 182 RLSYAFSVWRMEGAWSMSASH 202
           RLSYAFSVWRMEGAWSMSASH
Sbjct: 140 RLSYAFSVWRMEGAWSMSASH 160


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 65/170 (38%), Positives = 78/170 (45%), Gaps = 21/170 (12%)

Query: 6   SSSPVSPADDSLSNSE-----EEPDRQQPPSGKRGGRKRRSSRRSA---GGGAGPGGAAG 57
           S    SP DDS    E        D +  P    GG K      +A   GG + P G  G
Sbjct: 142 SGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLG 201

Query: 58  GGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRE 117
           GG GGG   GS          +G GGG G+G GG SSS   S +  +E +  R+  N RE
Sbjct: 202 GGGGGGSSSGS----------SGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARE 251

Query: 118 RQRTQSLNEAFAALRKIIPTLPSD---KLSKIQTLKLAARYIDFLYQVLQ 164
           R+R   LN+A   LR +IP   S    KLSKI TL LA  YI    Q L+
Sbjct: 252 RRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALE 301



 Score = 32.3 bits (72), Expect = 0.28
 Identities = 16/36 (44%), Positives = 16/36 (44%)

Query: 65  EPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSP 100
           EP  P          G GGGG AG GGG   G G P
Sbjct: 66  EPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVP 101



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 25/84 (29%)

Query: 24  PDRQQPPSGKRG--GRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGC 81
           P R++P S      G    +    AG    P G  GGG                  SAG 
Sbjct: 49  PPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGG------------------SAGS 90

Query: 82  GGGGGAGGG-----GGSSSGGGSP 100
           GGGGG G G      GS+  GG P
Sbjct: 91  GGGGGGGVGVPGLLVGSAGVGGDP 114


>gi|116805332 musculin [Homo sapiens]
          Length = 206

 Score = 81.6 bits (200), Expect = 4e-16
 Identities = 65/189 (34%), Positives = 93/189 (49%), Gaps = 36/189 (19%)

Query: 2   MQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVG 61
           ++ V  S  SP+D+S S  EE+PD          G + R +  +AG   G          
Sbjct: 31  LRGVERSYASPSDNS-SAEEEDPD----------GEEERCALGTAGSAEG---------- 69

Query: 62  GGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRT 121
                    + KR  + AG GG GG+ GGGG         + E  Q+QR  AN RER R 
Sbjct: 70  --------CKRKR-PRVAGGGGAGGSAGGGGKKPLPAKGSAAECKQSQRNAANARERARM 120

Query: 122 QSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAH 180
           + L++AF+ L+  +P +P D KLSK+ TL+LA+ YI  L Q+LQ D  ++      YV  
Sbjct: 121 RVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLLQEDRYEN-----GYVHP 175

Query: 181 ERLSYAFSV 189
             L++ F V
Sbjct: 176 VNLTWPFVV 184


>gi|148922889 scleraxis homolog B [Homo sapiens]
          Length = 201

 Score = 77.4 bits (189), Expect = 8e-15
 Identities = 51/108 (47%), Positives = 62/108 (57%), Gaps = 3/108 (2%)

Query: 62  GGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQT-QRVMANVRERQR 120
           G D  GS  +  R   +A CG  G     GG  +GGG P      +  QR  AN RER R
Sbjct: 29  GSDSSGSDEKPCR-VHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANARERDR 87

Query: 121 TQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 167
           T S+N AF ALR +IPT P+D KLSKI+TL+LA+ YI  L  VL + E
Sbjct: 88  TNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135


>gi|186972126 scleraxis homolog A [Homo sapiens]
          Length = 201

 Score = 77.4 bits (189), Expect = 8e-15
 Identities = 51/108 (47%), Positives = 62/108 (57%), Gaps = 3/108 (2%)

Query: 62  GGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQT-QRVMANVRERQR 120
           G D  GS  +  R   +A CG  G     GG  +GGG P      +  QR  AN RER R
Sbjct: 29  GSDSSGSDEKPCR-VHAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANARERDR 87

Query: 121 TQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 167
           T S+N AF ALR +IPT P+D KLSKI+TL+LA+ YI  L  VL + E
Sbjct: 88  TNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGE 135


>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
           sapiens]
          Length = 199

 Score = 76.6 bits (187), Expect = 1e-14
 Identities = 48/93 (51%), Positives = 56/93 (60%), Gaps = 6/93 (6%)

Query: 77  KSAGCGGGG-----GAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAAL 131
           +S GC  G      G G GGG  +GGG       +  QR  AN RER RTQS+N AF AL
Sbjct: 36  QSFGCCEGPEAARRGPGPGGGRRAGGGGGAGPVVVVRQRQAANARERDRTQSVNTAFTAL 95

Query: 132 RKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVL 163
           R +IPT P D KLSKI+TL+LA+ YI  L  VL
Sbjct: 96  RTLIPTEPVDRKLSKIETLRLASSYIAHLANVL 128


>gi|30039710 pancreas specific transcription factor, 1a [Homo
           sapiens]
          Length = 328

 Score = 75.5 bits (184), Expect = 3e-14
 Identities = 53/128 (41%), Positives = 68/128 (53%), Gaps = 8/128 (6%)

Query: 47  GGGAGPGGAAGGGVGGGD-EPGSPAQ------GKRGKKSAGCGGGGGAGGGGGSSSGGGS 99
           GGG G     G   GG    PGSP              S G    G +G    ++     
Sbjct: 95  GGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRR 154

Query: 100 PQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDF 158
            +S  ELQ  R  ANVRER+R QS+N+AF  LR  IPTLP +K LSK+ TL+LA  YI+F
Sbjct: 155 VRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINF 214

Query: 159 LYQVLQSD 166
           L +++Q+D
Sbjct: 215 LSELVQAD 222



 Score = 35.4 bits (80), Expect = 0.033
 Identities = 16/25 (64%), Positives = 16/25 (64%)

Query: 47  GGGAGPGGAAGGGVGGGDEPGSPAQ 71
           GG  G GG  GGG  GGD PGS AQ
Sbjct: 228 GGAGGCGGPGGGGRLGGDSPGSQAQ 252



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 13/23 (56%), Positives = 14/23 (60%)

Query: 74  RGKKSAGCGGGGGAGGGGGSSSG 96
           RG  + GCGG GG G  GG S G
Sbjct: 226 RGGGAGGCGGPGGGGRLGGDSPG 248



 Score = 28.9 bits (63), Expect = 3.1
 Identities = 16/33 (48%), Positives = 18/33 (54%), Gaps = 4/33 (12%)

Query: 80  GCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVM 112
           G G GG  G GGG   GG SP S    Q Q+V+
Sbjct: 227 GGGAGGCGGPGGGGRLGGDSPGS----QAQKVI 255


>gi|31077092 neurogenin 2 [Homo sapiens]
          Length = 272

 Score = 70.9 bits (172), Expect = 7e-13
 Identities = 60/168 (35%), Positives = 85/168 (50%), Gaps = 29/168 (17%)

Query: 6   SSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDE 65
           S+SP   A   LS+S +E + ++P  G  GG     +RR  G  AG G  A GGV  G E
Sbjct: 22  SASPALAALTPLSSSADEEEEEEP--GASGG-----ARRQRGAEAGQG--ARGGVAAGAE 72

Query: 66  PGSPAQ-------GKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQ-TQRVMANVRE 117
              PA+        KR    A              S G  + ++ + ++ T+R+ AN RE
Sbjct: 73  GCRPARLLGLVHDCKRRPSRARA-----------VSRGAKTAETVQRIKKTRRLKANNRE 121

Query: 118 RQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 164
           R R  +LN A  ALR+++PT P D KL+KI+TL+ A  YI  L + L+
Sbjct: 122 RNRMHNLNAALDALREVLPTFPEDAKLTKIETLRFAHNYIWALTETLR 169


>gi|5031943 nescient helix loop helix 1 [Homo sapiens]
          Length = 133

 Score = 70.1 bits (170), Expect = 1e-12
 Identities = 49/118 (41%), Positives = 59/118 (50%), Gaps = 14/118 (11%)

Query: 47  GGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEEL 106
           GGGAGP GA  GG GGG   G P  G+ G+K                 S     +     
Sbjct: 27  GGGAGPDGAGPGGPGGGQARG-PEPGEPGRKDL------------QHLSREERRRRRRAT 73

Query: 107 QTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVL 163
              R     RER R ++ N AFA LRK++PTLP D KLSKI+ L+LA  YI +L  VL
Sbjct: 74  AKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVL 131


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 67.4 bits (163), Expect = 8e-12
 Identities = 40/85 (47%), Positives = 52/85 (61%), Gaps = 7/85 (8%)

Query: 84  GGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-K 142
           GG   G G    GG  P        +R  AN +ER+RTQS+N AFA LR+ IP +P+D K
Sbjct: 81  GGVPPGAGPPGLGGPRPVK------RRGTANRKERRRTQSINSAFAELRECIPNVPADTK 134

Query: 143 LSKIQTLKLAARYIDFLYQVLQSDE 167
           LSKI+TL+LA  YI +L  +L  D+
Sbjct: 135 LSKIKTLRLATSYIAYLMDLLAKDD 159


>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
          Length = 108

 Score = 66.6 bits (161), Expect = 1e-11
 Identities = 35/62 (56%), Positives = 45/62 (72%), Gaps = 1/62 (1%)

Query: 108 TQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 166
           T+++  N RER R Q++N AFA LRK+IPT P D KLSK +TL+LA RYI+FL +VL   
Sbjct: 2   TRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQ 61

Query: 167 EL 168
            L
Sbjct: 62  SL 63


>gi|239749439 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 45/115 (39%), Positives = 56/115 (48%), Gaps = 11/115 (9%)

Query: 53  GGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVM 112
           G  AG  +    EP   A   R  +  G  G G AG GGGS SG G P +          
Sbjct: 4   GRPAGSPLSASAEPAPLAAAIRDSRP-GRTGPGPAGPGGGSRSGSGRPAAANA------- 55

Query: 113 ANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 166
              RER R Q+L  AF  L++ +P++P D KLSK+  L LA  YI  L + LQ D
Sbjct: 56  --ARERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDD 108


>gi|239743573 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 45/115 (39%), Positives = 56/115 (48%), Gaps = 11/115 (9%)

Query: 53  GGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVM 112
           G  AG  +    EP   A   R  +  G  G G AG GGGS SG G P +          
Sbjct: 4   GRPAGSPLSASAEPAPLAAAIRDSRP-GRTGPGPAGPGGGSRSGSGRPAAANA------- 55

Query: 113 ANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 166
              RER R Q+L  AF  L++ +P++P D KLSK+  L LA  YI  L + LQ D
Sbjct: 56  --ARERSRVQTLRHAFLELQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDD 108


>gi|29126247 basic helix-loop-helix family, member a15 [Homo
           sapiens]
          Length = 189

 Score = 64.7 bits (156), Expect = 5e-11
 Identities = 45/123 (36%), Positives = 61/123 (49%), Gaps = 5/123 (4%)

Query: 38  KRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGG 97
           +RR+  +      G G   G     G EP    + +  + +A   G G     G S  GG
Sbjct: 9   RRRAPVQDTEATPGEGTPDGSLPNPGPEPAKGLRSRPARAAARAPGEGRRRRPGPSGPGG 68

Query: 98  GSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYI 156
               S +    +R+ +N RERQR   LN AF ALR++IP + +D KLSKI+TL LA  YI
Sbjct: 69  RRDSSIQ----RRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLTLAKNYI 124

Query: 157 DFL 159
             L
Sbjct: 125 KSL 127


>gi|38202237 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 63.9 bits (154), Expect = 9e-11
 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 14/123 (11%)

Query: 76  KKSAGCGGGGGAGGGGGSSSGGGSPQ--------SYEELQTQRVMANVRERQRTQSLNEA 127
           ++S+ C  G    G GG      +P         S E  Q QR  AN RER R + L++A
Sbjct: 39  EESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKA 98

Query: 128 FAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYA 186
           F+ L+  +P +P D KLSK+ TL+LA+ YI  L Q+L +D+ ++      Y+    L++ 
Sbjct: 99  FSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYEN-----GYIHPVNLTWP 153

Query: 187 FSV 189
           F V
Sbjct: 154 FMV 156


>gi|38202239 transcription factor 21 [Homo sapiens]
          Length = 179

 Score = 63.9 bits (154), Expect = 9e-11
 Identities = 43/123 (34%), Positives = 65/123 (52%), Gaps = 14/123 (11%)

Query: 76  KKSAGCGGGGGAGGGGGSSSGGGSPQ--------SYEELQTQRVMANVRERQRTQSLNEA 127
           ++S+ C  G    G GG      +P         S E  Q QR  AN RER R + L++A
Sbjct: 39  EESSNCENGSPQKGRGGLGKRRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKA 98

Query: 128 FAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYA 186
           F+ L+  +P +P D KLSK+ TL+LA+ YI  L Q+L +D+ ++      Y+    L++ 
Sbjct: 99  FSRLKTTLPWVPPDTKLSKLDTLRLASSYIAHLRQILANDKYEN-----GYIHPVNLTWP 153

Query: 187 FSV 189
           F V
Sbjct: 154 FMV 156


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 32/68 (47%), Positives = 35/68 (51%)

Query: 32  GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGG 91
           G  GG    SS    GGG+  GG++GGG GGG   G       G    G  GGGG G GG
Sbjct: 485 GGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGG 544

Query: 92  GSSSGGGS 99
           GSS GG S
Sbjct: 545 GSSGGGSS 552



 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 35/81 (43%), Positives = 38/81 (46%), Gaps = 13/81 (16%)

Query: 32  GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDE----------PGSPAQGKRGKKSAGC 81
           G  GG          G G G GG++GGG GGG             GS + G  G  S G 
Sbjct: 471 GGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGY 530

Query: 82  GG---GGGAGGGGGSSSGGGS 99
           GG   GGG GG GG SSGGGS
Sbjct: 531 GGGSSGGGGGGYGGGSSGGGS 551



 Score = 55.8 bits (133), Expect = 2e-08
 Identities = 28/55 (50%), Positives = 31/55 (56%), Gaps = 1/55 (1%)

Query: 45  SAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGG-GAGGGGGSSSGGG 98
           S+GGG   GG+ GGG GGG   G  + G  G    G  GGG G G  GG SSGGG
Sbjct: 458 SSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGG 512



 Score = 54.7 bits (130), Expect = 5e-08
 Identities = 34/69 (49%), Positives = 37/69 (53%), Gaps = 7/69 (10%)

Query: 35  GGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGG---- 90
           GGR   S     GGG+  GG++GGG GGG   GS   G  G  S G   GGG GGG    
Sbjct: 462 GGRGGGSFGGGYGGGSSGGGSSGGGHGGG-HGGSSGGGYGGGSSGGGSSGGGYGGGSSSG 520

Query: 91  --GGSSSGG 97
             GGSSSGG
Sbjct: 521 GHGGSSSGG 529



 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 24/53 (45%), Positives = 25/53 (47%)

Query: 47  GGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGS 99
           GGG+  GG  GG  GGG   G    G  G    G GGG   GG  G   GGGS
Sbjct: 465 GGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGS 517



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 32/76 (42%), Positives = 33/76 (43%), Gaps = 14/76 (18%)

Query: 38 KRRSSRRSAGGGAGPGGAAGGGV------------GGGDEPGSPAQG--KRGKKSAGCGG 83
          K  SS RS GGG G G   GGGV            GGG   G  + G   RG    GC G
Sbjct: 9  KHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFG 68

Query: 84 GGGAGGGGGSSSGGGS 99
          G   G GG    GGGS
Sbjct: 69 GSSGGYGGLGGFGGGS 84



 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 28/59 (47%), Positives = 30/59 (50%), Gaps = 6/59 (10%)

Query: 51  GPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGG------GGGSSSGGGSPQSY 103
           G G + GGG GGG   G    G  G  S+G G GGG GG      GGGSS GG S   Y
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGY 513



 Score = 48.5 bits (114), Expect = 4e-06
 Identities = 30/63 (47%), Positives = 31/63 (49%), Gaps = 10/63 (15%)

Query: 45  SAGGGAGPG---GAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGG-------GGGSS 94
           S GGG G G   G  GGG  GG   G    G  G  S G  GGG +GG       GGGSS
Sbjct: 459 SGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSS 518

Query: 95  SGG 97
           SGG
Sbjct: 519 SGG 521



 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 29/71 (40%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 32  GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGG 91
           G  GG     S     GG+  GG  GG  GGG        G  G  S+G G   G G GG
Sbjct: 507 GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGG-------GGYGGGSSGGGSSSGGGYGG 559

Query: 92  GSSSGGGSPQS 102
           GSSSGG    S
Sbjct: 560 GSSSGGHKSSS 570



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 30/71 (42%), Positives = 33/71 (46%), Gaps = 7/71 (9%)

Query: 35  GGRKRRSSRRSAGGGAGPGGAAG-----GGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGG 89
           GG    S  R + GG   GG++G     GG GGG   GS      G    G  GGG  GG
Sbjct: 50  GGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGG 109

Query: 90  G--GGSSSGGG 98
           G  GG S GGG
Sbjct: 110 GSFGGGSFGGG 120



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 28/69 (40%), Positives = 30/69 (43%), Gaps = 14/69 (20%)

Query: 31  SGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGG 90
           SG  GG        S G G G  G  GGG GGG   G          S+G G GGG+  G
Sbjct: 519 SGGHGGSS------SGGYGGGSSGGGGGGYGGGSSGGG--------SSSGGGYGGGSSSG 564

Query: 91  GGSSSGGGS 99
           G  SS  GS
Sbjct: 565 GHKSSSSGS 573



 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 33/74 (44%), Positives = 36/74 (48%), Gaps = 6/74 (8%)

Query: 32 GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGD-EPGSPAQGKRGKKSAGCGGGGGAGGG 90
          G  GG    S R S+  G+  GG + GG  GG    GS   G  G  S G GG GG GGG
Sbjct: 24 GCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGG 83

Query: 91 G-----GSSSGGGS 99
                GSSS GGS
Sbjct: 84 SFRGSYGSSSFGGS 97



 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 29/67 (43%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 32  GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGG--GGGAGG 89
           G  GG   R S  S+  G   GG+ GGG  GG   G  + G  G    G GG  GGG GG
Sbjct: 78  GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGG 137

Query: 90  GGGSSSG 96
            GG  SG
Sbjct: 138 DGGLLSG 144



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 28/69 (40%), Positives = 30/69 (43%), Gaps = 12/69 (17%)

Query: 42  SRRSAGGGAGPGGAAG----GGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGG------- 90
           SR S+GGG   G + G    GG GGG   GS      G    G  GGG  GGG       
Sbjct: 58  SRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSF 117

Query: 91  -GGSSSGGG 98
            GG   GGG
Sbjct: 118 GGGGFGGGG 126



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 30/79 (37%), Positives = 34/79 (43%), Gaps = 20/79 (25%)

Query: 41  SSRRSAGGGAGPGG---------AAGGGVGGGDE---------PGSPAQGKRGKKSAGCG 82
           SS+ S GGG   GG         ++GGG  GG            G   +G  G  S G  
Sbjct: 38  SSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGS 97

Query: 83  GGGGAGGG--GGSSSGGGS 99
            GG  GGG  GG S GGGS
Sbjct: 98  YGGSFGGGSFGGGSFGGGS 116



 Score = 35.8 bits (81), Expect = 0.025
 Identities = 22/58 (37%), Positives = 25/58 (43%), Gaps = 15/58 (25%)

Query: 45  SAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQS 102
           S GGG G GG + GG               G  S G  GGG + GG  SSS G   +S
Sbjct: 535 SGGGGGGYGGGSSGG---------------GSSSGGGYGGGSSSGGHKSSSSGSVGES 577



 Score = 34.3 bits (77), Expect = 0.074
 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 6/64 (9%)

Query: 41 SSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGG--GGS----S 94
          S R S+        + GGG GGG   G      R   S G  GGG + GG  GGS    S
Sbjct: 2  SVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGS 61

Query: 95 SGGG 98
          SGGG
Sbjct: 62 SGGG 65



 Score = 33.1 bits (74), Expect = 0.16
 Identities = 15/29 (51%), Positives = 17/29 (58%)

Query: 71  QGKRGKKSAGCGGGGGAGGGGGSSSGGGS 99
           +G+      G GGG   GG GG SSGGGS
Sbjct: 454 EGEGSSGGGGRGGGSFGGGYGGGSSGGGS 482


>gi|239754900 PREDICTED: similar to transcription factor 23 [Homo
           sapiens]
          Length = 167

 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 44/115 (38%), Positives = 56/115 (48%), Gaps = 11/115 (9%)

Query: 53  GGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVM 112
           G  AG  +    EP   A   R  +  G  G G AG GGGS SG G P +          
Sbjct: 4   GRPAGSPLSASAEPAPLAAAIRDXRP-GRTGPGPAGLGGGSCSGSGRPAAENA------- 55

Query: 113 ANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 166
              RER R Q+L  AF  +++ +P++P D KLSK+  L LA  YI  L + LQ D
Sbjct: 56  --ARERSRVQTLRHAFLEVQRTLPSVPPDTKLSKLDVLLLATTYIAHLTRSLQDD 108


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 61.6 bits (148), Expect = 4e-10
 Identities = 34/72 (47%), Positives = 37/72 (51%), Gaps = 8/72 (11%)

Query: 31  SGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGD---EPGSPAQGKRGKKSAGCGGGGGA 87
           SG RGG     S  S GGG+G GG +GGG GGG      G    G  G      GGG G+
Sbjct: 510 SGSRGG-----SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGS 564

Query: 88  GGGGGSSSGGGS 99
           GGG G   GGGS
Sbjct: 565 GGGSGGGYGGGS 576



 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 32/68 (47%), Positives = 35/68 (51%), Gaps = 8/68 (11%)

Query: 32  GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGG 91
           G  GG   R SR  +GG  G GG +GGG GGG        G RG      GGG G+GGG 
Sbjct: 479 GGSGGSYGRGSRGGSGGSYG-GGGSGGGYGGGS-------GSRGGSGGSYGGGSGSGGGS 530

Query: 92  GSSSGGGS 99
           G   GGGS
Sbjct: 531 GGGYGGGS 538



 Score = 57.8 bits (138), Expect = 6e-09
 Identities = 32/72 (44%), Positives = 35/72 (48%), Gaps = 7/72 (9%)

Query: 31  SGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGG 90
           SG  GG     S  + GGG+G GG +GGG GGG        G RG      GGG G GG 
Sbjct: 543 SGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG-------SGSRGGSGGSHGGGSGFGGE 595

Query: 91  GGSSSGGGSPQS 102
            G S GGG   S
Sbjct: 596 SGGSYGGGEEAS 607



 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 28/66 (42%), Positives = 32/66 (48%)

Query: 32  GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGG 91
           G RGG         +GGG G G  + GG GG    GS + G  G    G  GGG +GG G
Sbjct: 488 GSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSG 547

Query: 92  GSSSGG 97
           G  SGG
Sbjct: 548 GGHSGG 553



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 34/79 (43%), Positives = 36/79 (45%), Gaps = 10/79 (12%)

Query: 31  SGKRGGRKRRSSRR-------SAGGGAGPGGAA---GGGVGGGDEPGSPAQGKRGKKSAG 80
           SG  GG  R   R        S GGG+G G +A   GGG GGG      A G     S G
Sbjct: 51  SGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGG 110

Query: 81  CGGGGGAGGGGGSSSGGGS 99
            GGG G G GGG   G GS
Sbjct: 111 FGGGFGGGSGGGFGGGYGS 129



 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 25/54 (46%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 44  RSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGG 97
           R  GG +G G ++ GG GGG   GS   G  G   +G GG GG GGG G   GG
Sbjct: 95  RGFGGASGGGYSSSGGFGGGFGGGSGG-GFGGGYGSGFGGFGGFGGGAGGGDGG 147



 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 10/73 (13%)

Query: 31  SGKRGGRKRRSSRRSAGGGAGPG--------GAAGGGVGGGDEPGSPAQGKRGKKSAGCG 82
           SG  GG     S   +GGG+G G        G +GG  GGG   G  + G  G      G
Sbjct: 551 SGGSGGNYGGGS--GSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASG 608

Query: 83  GGGGAGGGGGSSS 95
            GGG GGG G SS
Sbjct: 609 SGGGYGGGSGKSS 621



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 29/69 (42%), Positives = 33/69 (47%)

Query: 31  SGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGG 90
           SG  GG  R SS    GGG+      GGG   G   G  + G     S G G GGG+ G 
Sbjct: 38  SGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGF 97

Query: 91  GGSSSGGGS 99
           GG+S GG S
Sbjct: 98  GGASGGGYS 106



 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 29/69 (42%), Positives = 36/69 (52%), Gaps = 5/69 (7%)

Query: 32 GKRGGRKRRSSRRSAGGGAGPGG--AAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGG 89
          G  G  +   SR S+ GG G GG  ++  G GGG    S   G+ G  S G   GGG+GG
Sbjct: 23 GSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGS---SRVCGRGGGGSFGYSYGGGSGG 79

Query: 90 GGGSSSGGG 98
          G  +SS GG
Sbjct: 80 GFSASSLGG 88



 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 11/118 (9%)

Query: 35  GGRKRRSSRRSAGGGAGPGGAAGGGVGGG--DEPGSPAQGKRGKKSAGCGGGGGAGGGGG 92
           GG     S  S GGG G G    GG  GG     G    G  G    G GGG G+G GG 
Sbjct: 75  GGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGF 134

Query: 93  SSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLP---SDKLSKIQ 147
              GGG+      + T        E+   Q LN   A+    +  L    +D  +KIQ
Sbjct: 135 GGFGGGAGGGDGGILT------ANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQ 186



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 10/62 (16%)

Query: 47 GGGAGPGG----------AAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSG 96
          GGG G GG          ++GGG GGG    S   G    +  G GGGG  G   G  SG
Sbjct: 19 GGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSG 78

Query: 97 GG 98
          GG
Sbjct: 79 GG 80



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 30/82 (36%), Positives = 31/82 (37%), Gaps = 18/82 (21%)

Query: 34  RGGRKRRSSRRSAGGGA------------------GPGGAAGGGVGGGDEPGSPAQGKRG 75
           R    R SS    GGG                   G GG+ G   GGG   G  A    G
Sbjct: 29  RSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGG 88

Query: 76  KKSAGCGGGGGAGGGGGSSSGG 97
               G  G GGA GGG SSSGG
Sbjct: 89  GFGGGSRGFGGASGGGYSSSGG 110



 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 31/82 (37%), Positives = 33/82 (40%), Gaps = 16/82 (19%)

Query: 37  RKRRSSRRSAGGGAGPGGAAGGGV-------------GGGDEPGSPAQGKRGKKSAGCGG 83
           R+  SS  S  GG G GG   GG              GGG    S + G  G  S  CG 
Sbjct: 4   RQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGR 63

Query: 84  GGGAGGG---GGSSSGGGSPQS 102
           GGG   G   GG S GG S  S
Sbjct: 64  GGGGSFGYSYGGGSGGGFSASS 85



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 34/99 (34%), Positives = 45/99 (45%), Gaps = 17/99 (17%)

Query: 32  GKRGGRKRRSSRRSAGGGAGP--GGAAGGGVGGGDEPGSPAQGKRGKKSAGCGG-GGGAG 88
           G RG         S+ GG G   GG +GGG GGG           G    G GG GGGAG
Sbjct: 93  GSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGG----------YGSGFGGFGGFGGGAG 142

Query: 89  GGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEA 127
           GG G         + +EL ++  +A+  +  + Q+L EA
Sbjct: 143 GGDGGILTANEKSTMQELNSR--LASYLD--KVQALEEA 177


>gi|4758506 basic helix-loop-helix transcription factor HAND1 [Homo
           sapiens]
          Length = 215

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 45/120 (37%), Positives = 56/120 (46%), Gaps = 20/120 (16%)

Query: 52  PGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGA----GGGGGSSSGGGSPQSYEELQ 107
           P  AA     GG  P + A        A  G   G     GG  G   G G         
Sbjct: 49  PADAAPDFPAGGPPPAAAAAATAYGPDARPGQSPGRLEALGGRLGRRKGSGPK------- 101

Query: 108 TQRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSD 166
                   +ER+RT+S+N AFA LR+ IP +P+D KLSKI+TL+LA  YI +L  VL  D
Sbjct: 102 --------KERRRTESINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDVLAKD 153


>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
          Length = 331

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 32/60 (53%), Positives = 43/60 (71%), Gaps = 1/60 (1%)

Query: 109 QRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 167
           +R+  N RER R Q++N AFA LRK+IPT P D KLSK + L+LA +YI+FL ++L   E
Sbjct: 188 RRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILRLAMKYINFLAKLLNDQE 247



 Score = 30.0 bits (66), Expect = 1.4
 Identities = 19/54 (35%), Positives = 20/54 (37%), Gaps = 19/54 (35%)

Query: 71  QGKRGKKSAGCGGGGGAGGGGG-------------------SSSGGGSPQSYEE 105
           + K GK      GGGG GGGGG                   S  G  SP SY E
Sbjct: 253 RAKTGKDPVVGAGGGGGGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYTE 306


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 35/80 (43%), Positives = 39/80 (48%), Gaps = 9/80 (11%)

Query: 19  NSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKS 78
           N  E P  + PP  KR  ++    R   GGG G GG  GGG GGG       +G  G   
Sbjct: 313 NEIEPPPPEMPPWQKR--QEGGGGRGGWGGGGGGGGRGGGGGGGG-------RGGWGGGG 363

Query: 79  AGCGGGGGAGGGGGSSSGGG 98
            G GGGGG GGG G   GGG
Sbjct: 364 GGWGGGGGGGGGWGGGGGGG 383



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 31/79 (39%), Positives = 33/79 (41%), Gaps = 12/79 (15%)

Query: 32  GKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKS-----AGCGG--- 83
           G  GGR          GG G GG   GG GGG   G   +G  G +       G GG   
Sbjct: 351 GGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGY 410

Query: 84  ----GGGAGGGGGSSSGGG 98
               GGG GGGGG   GGG
Sbjct: 411 GDPYGGGGGGGGGGGGGGG 429



 Score = 34.3 bits (77), Expect = 0.074
 Identities = 18/41 (43%), Positives = 19/41 (46%)

Query: 58  GGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGG 98
           GG     EP  P      K+  G GG GG GGGGG    GG
Sbjct: 309 GGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGG 349


>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
           sapiens]
          Length = 280

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 31/57 (54%), Positives = 42/57 (73%), Gaps = 1/57 (1%)

Query: 109 QRVMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 164
           +RV  N RER R Q++N AFA LRK++PT P D KLSK + L+LA +YI FL ++L+
Sbjct: 151 RRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLR 207


>gi|23097242 nephew of atonal 3 [Homo sapiens]
          Length = 166

 Score = 57.8 bits (138), Expect = 6e-09
 Identities = 31/60 (51%), Positives = 44/60 (73%), Gaps = 1/60 (1%)

Query: 109 QRVMANVRERQRTQSLNEAFAALRKIIPTLPSDK-LSKIQTLKLAARYIDFLYQVLQSDE 167
           QR  AN+RER+R  +LNEAF  LR+ +PT   +K LS+I+TL+LA  YI F+ ++L+S E
Sbjct: 102 QRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIETLRLAIVYISFMTELLESCE 161


>gi|4885075 atonal homolog 1 [Homo sapiens]
          Length = 354

 Score = 57.4 bits (137), Expect = 8e-09
 Identities = 42/117 (35%), Positives = 58/117 (49%), Gaps = 2/117 (1%)

Query: 51  GPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQR 110
           G G       GG     SP   K  ++     GG      G S     S +    +Q QR
Sbjct: 101 GRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQR 160

Query: 111 -VMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQS 165
            + AN RER+R   LN AF  LR +IP+  +D KLSK +TL++A  YI+ L ++LQ+
Sbjct: 161 RLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQT 217



 Score = 27.7 bits (60), Expect = 6.9
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 4/69 (5%)

Query: 18  SNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGG-VGGGDEPGSPAQGKRGK 76
           S  E+ P    PP+  +       +  S  GGAG   AAG     GG +  +P    R +
Sbjct: 219 SGGEQPPP---PPASCKSDHHHLRTAASYEGGAGNATAAGAQQASGGSQRPTPPGSCRTR 275

Query: 77  KSAGCGGGG 85
            SA    GG
Sbjct: 276 FSAPASAGG 284


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score = 57.4 bits (137), Expect = 8e-09
 Identities = 41/97 (42%), Positives = 48/97 (49%), Gaps = 19/97 (19%)

Query: 6   SSSP---VSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGG 62
           SS+P   VSP+ +  S+S   P      +         S+    GGG+G GGA GGG GG
Sbjct: 434 SSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHR-GGGSGSGGA-GGGSGG 491

Query: 63  GDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGS 99
           G   G              GGGGGAGGGGG SSGGGS
Sbjct: 492 GSGSG--------------GGGGGAGGGGGGSSGGGS 514


>gi|68989258 neurogenin 3 [Homo sapiens]
          Length = 214

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 41/105 (39%), Positives = 55/105 (52%), Gaps = 6/105 (5%)

Query: 66  PGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYE-----ELQTQRVMANVRERQR 120
           P SP + +     A  GG  GA     +  GG S    E     + +++R  AN RER R
Sbjct: 36  PPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNR 95

Query: 121 TQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQ 164
             +LN A  ALR ++PT P D KL+KI+TL+ A  YI  L Q L+
Sbjct: 96  MHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLR 140


>gi|21553337 atonal homolog 7 [Homo sapiens]
          Length = 152

 Score = 56.6 bits (135), Expect = 1e-08
 Identities = 39/104 (37%), Positives = 54/104 (51%), Gaps = 9/104 (8%)

Query: 65  EPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSL 124
           +P  P  G R   +  C GG    G   + +G G     E    +R+ AN RER+R Q L
Sbjct: 5   KPSGPPAGAR--VAPPCAGGTECAG---TCAGAGR---LESAARRRLAANARERRRMQGL 56

Query: 125 NEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQSDE 167
           N AF  LR+++P    D KLSK +TL++A  YI  L ++L   E
Sbjct: 57  NTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAE 100


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 31/65 (47%), Positives = 33/65 (50%), Gaps = 8/65 (12%)

Query: 42  SRRSAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGK--------KSAGCGGGGGAGGGGGS 93
           SR  AGGG G GG  GGG GGG   G    G  G          +A   GGGG GG GGS
Sbjct: 244 SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGS 303

Query: 94  SSGGG 98
           S+G G
Sbjct: 304 SAGYG 308



 Score = 40.4 bits (93), Expect = 0.001
 Identities = 31/91 (34%), Positives = 36/91 (39%), Gaps = 20/91 (21%)

Query: 29  PPSGKRGGRK-----RRSSRRSAGGGA--GPGGAAGGGVGGGDE--------PGS----- 68
           P SG  GGR      +   ++S G G       AA G  G  D         P S     
Sbjct: 181 PASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHY 240

Query: 69  PAQGKRGKKSAGCGGGGGAGGGGGSSSGGGS 99
           P   + G    G GGGGG GG GG   GGG+
Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGA 271



 Score = 33.9 bits (76), Expect = 0.097
 Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 4/56 (7%)

Query: 45  SAGGGAGPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAG---GGGGSSSGG 97
           +A  G G GG  GG   G     SP Q + G    G GGGG A       GS++GG
Sbjct: 289 AAAAGGGGGGGYGGSSAGYGVLSSPRQ-QGGGMMMGPGGGGAASLSKAAAGSAAGG 343



 Score = 32.0 bits (71), Expect = 0.37
 Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 15/111 (13%)

Query: 12  PADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGDEP----- 66
           P    LS   +E D         GGR       + G    P    GGG G    P     
Sbjct: 116 PGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNY 175

Query: 67  ---GSPAQGKRGKKSAGC----GGGGGAGGG---GGSSSGGGSPQSYEELQ 107
               +PA G  G ++  C    GG    G G     S++  G+P S + LQ
Sbjct: 176 YGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQ 226


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.369 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,612,410
Number of Sequences: 37866
Number of extensions: 623404
Number of successful extensions: 28317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 978
Number of HSP's successfully gapped in prelim test: 718
Number of HSP's that attempted gapping in prelim test: 6870
Number of HSP's gapped (non-prelim): 9574
length of query: 202
length of database: 18,247,518
effective HSP length: 97
effective length of query: 105
effective length of database: 14,574,516
effective search space: 1530324180
effective search space used: 1530324180
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.