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Search of human proteins with 4507691
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507691 transformation/transcription domain-associated
protein [Homo sapiens]
(3830 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507691 transformation/transcription domain-associated protei... 7630 0.0
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom... 92 8e-18
gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad... 92 8e-18
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 74 4e-12
gi|4826730 FK506 binding protein 12-rapamycin associated protein... 73 5e-12
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 68 2e-10
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated... 68 2e-10
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens] 59 1e-07
gi|153792074 proline rich 12 [Homo sapiens] 57 4e-07
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 57 5e-07
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 56 6e-07
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 56 6e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 56 8e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 56 8e-07
gi|158534059 formin binding protein 4 [Homo sapiens] 55 1e-06
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 55 2e-06
gi|4557329 fas ligand [Homo sapiens] 54 2e-06
gi|90903231 huntingtin [Homo sapiens] 54 3e-06
gi|56549694 enabled homolog isoform a [Homo sapiens] 54 4e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 54 4e-06
gi|148613878 acrosin precursor [Homo sapiens] 53 5e-06
gi|149944526 additional sex combs like 3 [Homo sapiens] 53 5e-06
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 52 9e-06
gi|33356148 formin-like 1 [Homo sapiens] 52 9e-06
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 52 1e-05
gi|52485606 formin-like 2 [Homo sapiens] 52 1e-05
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 52 1e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 52 1e-05
gi|39812378 RAN binding protein 9 [Homo sapiens] 52 1e-05
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 51 2e-05
>gi|4507691 transformation/transcription domain-associated protein
[Homo sapiens]
Length = 3830
Score = 7630 bits (19797), Expect = 0.0
Identities = 3830/3830 (100%), Positives = 3830/3830 (100%)
Query: 1 MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYST 60
MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYST
Sbjct: 1 MAFVATQGATVVDQTTLMKKYLQFVAALTDVNTPDETKLKMMQEVSENFENVTSSPQYST 60
Query: 61 FLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRF 120
FLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRF
Sbjct: 61 FLEHIIPRFLTFLQDGEVQFLQEKPAQQLRKLVLEIIHRIPTNEHLRPHTKNVLSVMFRF 120
Query: 121 LETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIP 180
LETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIP
Sbjct: 121 LETENEENVLICLRIIIELHKQFRPPITQEIHHFLDFVKQIYKELPKVVNRYFENPQVIP 180
Query: 181 ENTVPPPEMVGMITTIAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYK 240
ENTVPPPEMVGMITTIAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYK
Sbjct: 181 ENTVPPPEMVGMITTIAVKVNPEREDSETRTHSIIPRGSLSLKVLAELPIIVVLMYQLYK 240
Query: 241 LNIHNVVAEFVPLIMNTIAIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQE 300
LNIHNVVAEFVPLIMNTIAIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQE
Sbjct: 241 LNIHNVVAEFVPLIMNTIAIQVSAQARQHKLYNKELYADFIAAQIKTLSFLAYIIRIYQE 300
Query: 301 LVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESIL 360
LVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESIL
Sbjct: 301 LVTKYSQQMVKGMLQLLSNCPAETAHLRKELLIAAKHILTTELRNQFIPCMDKLFDESIL 360
Query: 361 IGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSC 420
IGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSC
Sbjct: 361 IGSGYTARETLRPLAYSTLADLVHHVRQHLPLSDLSLAVQLFAKNIDDESLPSSIQTMSC 420
Query: 421 KLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAV 480
KLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAV
Sbjct: 421 KLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAV 480
Query: 481 EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQT 540
EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQT
Sbjct: 481 EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQT 540
Query: 541 FQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQAL 600
FQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQAL
Sbjct: 541 FQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYIKLVKYAMQAL 600
Query: 601 DIYQVQIAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVE 660
DIYQVQIAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVE
Sbjct: 601 DIYQVQIAGNGQTYIRVANCQTVRMKEEKEVLEHFAGVFTMMNPLTFKEIFQTTVPYMVE 660
Query: 661 RISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGS 720
RISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGS
Sbjct: 661 RISKNYALQIVANSFLANPTTSALFATILVEYLLDRLPEMGSNVELSNLYLKLFKLVFGS 720
Query: 721 VSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFL 780
VSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFL
Sbjct: 721 VSLFAAENEQMLKPHLHKIVNSSMELAQTAKEPYNYFLLLRALFRSIGGGSHDLLYQEFL 780
Query: 781 PLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQT 840
PLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQT
Sbjct: 781 PLLPNLLQGLNMLQSGLHKQHMKDLFVELCLTVPVRLSSLLPYLPMLMDPLVSALNGSQT 840
Query: 841 LVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGG 900
LVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGG
Sbjct: 841 LVSQGLRTLELCVDNLQPDFLYDHIQPVRAELMQALWRTLRNPADSISHVAYRVLGKFGG 900
Query: 901 SNRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYR 960
SNRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYR
Sbjct: 901 SNRKMLKESQKLHYVVTEVQGPSITVEFSDCKASLQLPMEKAIETALDCLKSANTEPYYR 960
Query: 961 RQAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPARKTFEQ 1020
RQAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPARKTFEQ
Sbjct: 961 RQAWEVIKCFLVAMMSLEDNKHALYQLLAHPNFTEKTIPNVIISHRYKAQDTPARKTFEQ 1020
Query: 1021 ALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSE 1080
ALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSE
Sbjct: 1021 ALTGAFMSAVIKDLRPSALPFVASLIRHYTMVAVAQQCGPFLLPCYQVGSQPSTAMFHSE 1080
Query: 1081 ENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSY 1140
ENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSY
Sbjct: 1081 ENGSKGMDPLVLIDAIAICMAYEEKELCKIGEVALAVIFDVASIILGSKERACQLPLFSY 1140
Query: 1141 IVERLCACCYEQAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKALLFVMMDLTGEVSN 1200
IVERLCACCYEQAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKALLFVMMDLTGEVSN
Sbjct: 1141 IVERLCACCYEQAWYAKLGGVVSIKFLMERLPLTWVLQNQQTFLKALLFVMMDLTGEVSN 1200
Query: 1201 GAVAMAKTTLEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQA 1260
GAVAMAKTTLEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQA
Sbjct: 1201 GAVAMAKTTLEQLLMRCATPLKDEERAEEIVAAQEKSFHHVTHDLVREVTSPNSTVRKQA 1260
Query: 1261 MHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQP 1320
MHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQP
Sbjct: 1261 MHSLQVLAQVTGKSVTVIMEPHKEVLQDMVPPKKHLLRHQPANAQIGLMEGNTFCTTLQP 1320
Query: 1321 RLFTMDLNVVEHKVFYTELLNLCEAEDSALTKLPCYKSLPSLVPLRIAALNALAACNYLP 1380
RLFTMDLNVVEHKVFYTELLNLCEAEDSALTKLPCYKSLPSLVPLRIAALNALAACNYLP
Sbjct: 1321 RLFTMDLNVVEHKVFYTELLNLCEAEDSALTKLPCYKSLPSLVPLRIAALNALAACNYLP 1380
Query: 1381 QSREKIIAALFKALNSTNSELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSL 1440
QSREKIIAALFKALNSTNSELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSL
Sbjct: 1381 QSREKIIAALFKALNSTNSELQEAGEACMRKFLEGATIEVDQIHTHMRPLLMMLGDYRSL 1440
Query: 1441 TLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAII 1500
TLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAII
Sbjct: 1441 TLNVVNRLTSVTRLFPNSFNDKFCDQMMQHLRKWMEVVVITHKGGQRSDGNEMKICSAII 1500
Query: 1501 NLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEAT 1560
NLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEAT
Sbjct: 1501 NLFHLIPAAPQTLVKPLLEVVMKTERAMLIEAGSPFREPLIKFLTRHPSQTVELFMMEAT 1560
Query: 1561 LNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSTMRLDL 1620
LNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSTMRLDL
Sbjct: 1561 LNDPQWSRMFMSFLKHKDARPLRDVLAANPNRFITLLLPGGAQTAVRPGSPSTSTMRLDL 1620
Query: 1621 QFQAIKIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERHRKENMAATNWKEPKLLAY 1680
QFQAIKIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERHRKENMAATNWKEPKLLAY
Sbjct: 1621 QFQAIKIISIIVKNDDSWLASQHSLVSQLRRVWVSENFQERHRKENMAATNWKEPKLLAY 1680
Query: 1681 CLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVD 1740
CLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVD
Sbjct: 1681 CLLNYCKRNYGDIELLFQLLRAFTGRFLCNMTFLKEYMEEEIPKNYSIAQKRALFFRFVD 1740
Query: 1741 FNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDP 1800
FNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDP
Sbjct: 1741 FNDPNFGDELKAKVLQHILNPAFLYSFEKGEGEQLLGPPNPEGDNPESITSVFITKVLDP 1800
Query: 1801 EKQADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPA 1860
EKQADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPA
Sbjct: 1801 EKQADMLDSLRIYLLQYATLLVEHAPHHIHDNNKNRNSKLRRLMTFAWPCLLSKACVDPA 1860
Query: 1861 CKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDG 1920
CKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDG
Sbjct: 1861 CKYSGHLLLAHIIAKFAIHKKIVLQVFHSLLKAHAMEARAIVRQAMAILTPAVPARMEDG 1920
Query: 1921 HQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSV 1980
HQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSV
Sbjct: 1921 HQMLTHWTRKIIVEEGHTVPQLVHILHLIVQHFKVYYPVRHHLVQHMVSAMQRLGFTPSV 1980
Query: 1981 TIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVNSVSSSIKRGLSVDSAQEV 2040
TIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVNSVSSSIKRGLSVDSAQEV
Sbjct: 1981 TIEQRRLAVDLSEVVIKWELQRIKDQQPDSDMDPNSSGEGVNSVSSSIKRGLSVDSAQEV 2040
Query: 2041 KRFRTATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNFLIRVACQVNDNTNTAGSP 2100
KRFRTATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNFLIRVACQVNDNTNTAGSP
Sbjct: 2041 KRFRTATGAISAVFGRSQSLPGADSLLAKPIDKQHTDTVVNFLIRVACQVNDNTNTAGSP 2100
Query: 2101 GEVLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQVNYGNICTGLEVLSFLL 2160
GEVLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQVNYGNICTGLEVLSFLL
Sbjct: 2101 GEVLSRRCVNLLKTALRPDMWPKSELKLQWFDKLLMTVEQPNQVNYGNICTGLEVLSFLL 2160
Query: 2161 TVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSIFPTEPSTSSVASKYEE 2220
TVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSIFPTEPSTSSVASKYEE
Sbjct: 2161 TVLQSPAILSSFKPLQRGIAACMTCGNTKVLRAVHSLLSRLMSIFPTEPSTSSVASKYEE 2220
Query: 2221 LECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQ 2280
LECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQ
Sbjct: 2221 LECLYAAVGKVIYEGLTNYEKATNANPSQLFGTLMILKSACSNNPSYIDRLISVFMRSLQ 2280
Query: 2281 KMVREHLNPQAASGSTEATSGTSELVMLSLELVKTRLAVMSMEMRKNFIQAILTSLIEKS 2340
KMVREHLNPQAASGSTEATSGTSELVMLSLELVKTRLAVMSMEMRKNFIQAILTSLIEKS
Sbjct: 2281 KMVREHLNPQAASGSTEATSGTSELVMLSLELVKTRLAVMSMEMRKNFIQAILTSLIEKS 2340
Query: 2341 PDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFL 2400
PDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFL
Sbjct: 2341 PDAKILRAVVKIVEEWVKNNSPMAANQTPTLREKSILLVKMMTYIEKRFPEDLELNAQFL 2400
Query: 2401 DLVNYVYRDETLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVT 2460
DLVNYVYRDETLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVT
Sbjct: 2401 DLVNYVYRDETLSGSELTAKLEPAFLSGLRCAQPLIRAKFFEVFDNSMKRRVYERLLYVT 2460
Query: 2461 CSQNWEAMGNHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPSITNVINLADSHDRAAFAM 2520
CSQNWEAMGNHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPSITNVINLADSHDRAAFAM
Sbjct: 2461 CSQNWEAMGNHFWIKQCIELLLAVCEKSTPIGTSCQGAMLPSITNVINLADSHDRAAFAM 2520
Query: 2521 VTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKF 2580
VTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKF
Sbjct: 2521 VTHVKQEPRERENSESKEEDVEIDIELAPGDQTSTPKTKELSEKDIGNQLHMLTNRHDKF 2580
Query: 2581 LDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCS 2640
LDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCS
Sbjct: 2581 LDTLREVKTGALLSAFVQLCHISTTLAEKTWVQLFPRLWKILSDRQQHALAGEISPFLCS 2640
Query: 2641 GSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKG 2700
GSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKG
Sbjct: 2641 GSHQVQRDCQPSALNCFVEAMSQCVPPIPIRPCVLKYLGKTHNLWFRSTLMLEHQAFEKG 2700
Query: 2701 LSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKYSETATAI 2760
LSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKYSETATAI
Sbjct: 2701 LSLQIKPKQTTEFYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKYSETATAI 2760
Query: 2761 AYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALT 2820
AYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALT
Sbjct: 2761 AYEQHGFFEQAQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALT 2820
Query: 2821 EYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEE 2880
EYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEE
Sbjct: 2821 EYGQSKGHINPYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEE 2880
Query: 2881 QQLSFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNL 2940
QQLSFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNL
Sbjct: 2881 QQLSFIERLVEMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNL 2940
Query: 2941 GRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQAIVTAYENSSQHDPSSNN 3000
GRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQAIVTAYENSSQHDPSSNN
Sbjct: 2941 GRNNSLHDMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQHHYQAIVTAYENSSQHDPSSNN 3000
Query: 3001 AMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQL 3060
AMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQL
Sbjct: 3001 AMLGVHASASAIIQYGKIARKQGLVNVALDILSRIHTIPTVPIVDCFQKIRQQVKCYLQL 3060
Query: 3061 AGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMH 3120
AGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMH
Sbjct: 3061 AGVMGKNECMQGLEVIESTNLKYFTKEMTAEFYALKGMFLAQINKSEEANKAFSAAVQMH 3120
Query: 3121 DVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFD 3180
DVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFD
Sbjct: 3121 DVLVKAWAMWGDYLENIFVKERQLHLGVSAITCYLHACRHQNESKSRKYLAKVLWLLSFD 3180
Query: 3181 DDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPI 3240
DDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPI
Sbjct: 3181 DDKNTLADAVDKYCIGVPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPI 3240
Query: 3241 RTLYLTLKIEQRERYKSDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFR 3300
RTLYLTLKIEQRERYKSDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFR
Sbjct: 3241 RTLYLTLKIEQRERYKSDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFR 3300
Query: 3301 ENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVS 3360
ENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVS
Sbjct: 3301 ENWHEEVLRQLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVS 3360
Query: 3361 TMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILE 3420
TMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILE
Sbjct: 3361 TMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILE 3420
Query: 3421 AKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKH 3480
AKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKH
Sbjct: 3421 AKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKH 3480
Query: 3481 NTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFF 3540
NTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFF
Sbjct: 3481 NTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFF 3540
Query: 3541 TVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQA 3600
TVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQA
Sbjct: 3541 TVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQARGTQA 3600
Query: 3601 SHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLN 3660
SHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLN
Sbjct: 3601 SHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHLN 3660
Query: 3661 RLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLT 3720
RLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLT
Sbjct: 3661 RLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLT 3720
Query: 3721 ASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVS 3780
ASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVS
Sbjct: 3721 ASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQEDTSSPLSAAGQPENMDSQQLVS 3780
Query: 3781 LVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWL 3830
LVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWL
Sbjct: 3781 LVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAANSLDNLCRMDPAWHPWL 3830
>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
sapiens]
Length = 2644
Score = 92.4 bits (228), Expect = 8e-18
Identities = 87/376 (23%), Positives = 162/376 (43%), Gaps = 19/376 (5%)
Query: 3458 PKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVL 3517
P P H+ IA F VEI+ +++ ++G +GK Y +M + R++ R++
Sbjct: 2285 PFPGHWAY-IAGFDDMVEILASLQKP-KKISLKGSDGKFY---IMMCKPKDDLRKDCRLM 2339
Query: 3518 QLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGI 3577
+ L+N CL K E+ +R L V+ ++ + ++E ++ L I + +KG+
Sbjct: 2340 EFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGV 2399
Query: 3578 EHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRS--MLKEWALHTFPNATD 3635
Y Q +++ L + LK + ++PR + EW L TFP+ T
Sbjct: 2400 --------YMTGKELRQCMLPKSA--ALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTS 2449
Query: 3636 YWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDAN 3695
+++ R + A++ ++L L + E + TG+ F N +
Sbjct: 2450 WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGE-TFEVP 2508
Query: 3696 RPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKK 3755
VPFRLT N+ + +G G + R + +LKT L D ++ W K
Sbjct: 2509 EIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKP 2568
Query: 3756 TQEDTSSPLSAAGQPENMDSQ-QLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAAN 3814
+ + +PL+ G+ N ++ ++ + Q+ I TR E V+ L+ A
Sbjct: 2569 VKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEAT 2628
Query: 3815 SLDNLCRMDPAWHPWL 3830
+ LC+M W P++
Sbjct: 2629 DENLLCQMYLGWTPYM 2644
>gi|169165926 PREDICTED: similar to ataxia telangiectasia and Rad3
related protein, partial [Homo sapiens]
Length = 386
Score = 92.4 bits (228), Expect = 8e-18
Identities = 87/376 (23%), Positives = 162/376 (43%), Gaps = 19/376 (5%)
Query: 3458 PKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVL 3517
P P H+ IA F VEI+ +++ ++G +GK Y +M + R++ R++
Sbjct: 27 PFPGHWAY-IAGFDDMVEILASLQKP-KKISLKGSDGKFY---IMMCKPKDDLRKDCRLM 81
Query: 3518 QLLRLLNPCLEKRKETTKRHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGI 3577
+ L+N CL K E+ +R L V+ ++ + ++E ++ L I + +KG+
Sbjct: 82 EFNSLINKCLRKDAESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGV 141
Query: 3578 EHDNPISRYYDRLATVQARGTQASHQVLRDILKEVQSNMVPRS--MLKEWALHTFPNATD 3635
Y Q +++ L + LK + ++PR + EW L TFP+ T
Sbjct: 142 --------YMTGKELRQCMLPKSA--ALSEKLKVFREFLLPRHPPIFHEWFLRTFPDPTS 191
Query: 3636 YWTFRKMFTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDAN 3695
+++ R + A++ ++L L + E + TG+ F N +
Sbjct: 192 WYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGE-TFEVP 250
Query: 3696 RPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKK 3755
VPFRLT N+ + +G G + R + +LKT L D ++ W K
Sbjct: 251 EIVPFRLTHNMVNGMGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKP 310
Query: 3756 TQEDTSSPLSAAGQPENMDSQ-QLVSLVQKAVTAIMTRLHNLAQFEGGESKVNTLVAAAN 3814
+ + +PL+ G+ N ++ ++ + Q+ I TR E V+ L+ A
Sbjct: 311 VKGHSKAPLNETGEVVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGHVHYLIQEAT 370
Query: 3815 SLDNLCRMDPAWHPWL 3830
+ LC+M W P++
Sbjct: 371 DENLLCQMYLGWTPYM 386
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 73.6 bits (179), Expect = 4e-12
Identities = 115/596 (19%), Positives = 229/596 (38%), Gaps = 100/596 (16%)
Query: 3197 VPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYK 3256
VP Q+++WI ++ L + + + + ++ YPQA+ +P I E Y
Sbjct: 3490 VPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPF--------IISSESYS 3541
Query: 3257 SDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLE--GIVDQMV----------WFRENWH 3304
++ + H +E + S L+ G++ + ++W
Sbjct: 3542 ------------FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWS 3589
Query: 3305 EEVLRQL------QQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN 3358
+V +L ++ + K Y + A+ D K P F +K + TFG +
Sbjct: 3590 NDVRAELAKTPVNKKNIEKMYERMY---AALGDPK-APGLGAFRRKFIQTFGKEFDK--- 3642
Query: 3359 VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKI 3418
F S+ L + LK + D PG++K + W+
Sbjct: 3643 ---HFGKGGSKLLRMKLSDFNDITNMLLLK----MNKDSKPPGNLK------ECSPWMS- 3688
Query: 3419 LEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFL---MPKPTHYYIKIARFMPRVE 3475
+ K FL N E+EIPG++ P P Y+++IA F RV
Sbjct: 3689 --------------DFKVEFLRN------ELEIPGQYDGRGKPLP-EYHVRIAGFDERVT 3727
Query: 3476 IVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK 3535
++ +R+ IRGH+ + +P+LV L R+++RV QL +++N L + ++
Sbjct: 3728 VMASLRRP-KRIIIRGHDEREHPFLVKGGEDL---RQDQRVEQLFQVMNGILAQDSACSQ 3783
Query: 3536 RHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKG-----IEHDNPISRYYDRL 3590
R L VV ++ ++ L+E ++++L ++ +++ + P Y D L
Sbjct: 3784 RALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWL 3843
Query: 3591 ATVQARGTQASHQVLRDILKEVQS--------NMVPRSMLKEWALHTFPNATDYWTFRKM 3642
+ + ++ ++ ++ + VP +LK + + + R
Sbjct: 3844 TKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLALRSH 3903
Query: 3643 FTIQLALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRL 3702
F ALI + ++L + + +A +TG + F AT L +PFRL
Sbjct: 3904 FASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRL 3963
Query: 3703 TPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQE 3758
T + + +G + + M+ R F + + +++ W Q+
Sbjct: 3964 TRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQK 4019
>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
[Homo sapiens]
Length = 2549
Score = 73.2 bits (178), Expect = 5e-12
Identities = 126/626 (20%), Positives = 237/626 (37%), Gaps = 96/626 (15%)
Query: 3196 GVPPIQ---WLAWIPQLLTCLVGSE---GKLLLNLISQVGRVYPQAVYFPIRTLYLTLKI 3249
GV IQ WL IPQL+ + G+L+ L++ +GR +PQA+ +P L + K
Sbjct: 1926 GVKAIQIDTWLQVIPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYP---LTVASKS 1982
Query: 3250 EQRERYKSDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLEGIVDQMVWFRENWHEEVLR 3309
R+ + ++I+ E TL+ + ++++ WHE
Sbjct: 1983 TTTARHNA-------------ANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHE---- 2025
Query: 3310 QLQQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAAS- 3368
+GL + + F + NV MF
Sbjct: 2026 MWHEGLEEASRLYFGER-------------------------------NVKGMFEVLEPL 2054
Query: 3369 ESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKW---IKILEAKTKQ 3425
++ R T ++ F + G+ + MK N+ + W + +KQ
Sbjct: 2055 HAMMERGPQTLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQ 2114
Query: 3426 LPKFFLIEEKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAAR 3485
LP+ +E + + E+ +PG + P I+I P ++++ R
Sbjct: 2115 LPQLTSLELQYVSPKLLMCRDLELAVPGTY---DPNQPIIRIQSIAPSLQVITSKQRP-R 2170
Query: 3486 RLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTKRHLFFTVPRV 3545
+L + G NG + +L+ L R++ERV+QL L+N L + +++L V
Sbjct: 2171 KLTLMGSNGHEFVFLLKGHEDL---RQDERVMQLFGLVNTLLANDPTSLRKNLSIQRYAV 2227
Query: 3546 VAVSPQMRLVEDNPSSLSLVEIYKQRCAKK----GIEHDNPISRY--YDRLATVQARGTQ 3599
+ +S L+ P +L + + KK IEH + YD L +Q
Sbjct: 2228 IPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLNIEHRIMLRMAPDYDHLTLMQKV--- 2284
Query: 3600 ASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEFVLHL 3659
++ + +N + K L + P++ ++ R +T LA++ ++L L
Sbjct: 2285 -------EVFEHAVNNTAGDDLAKLLWLKS-PSSEVWFDRRTNYTRSLAVMSMVGYILGL 2336
Query: 3660 NRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPL 3719
+P L + + +GK+ F A +PFRLT ++ + G+ G
Sbjct: 2337 GDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNY 2396
Query: 3720 TASMIAVARCFAQPNFKVDGILKTVLRDEIIAW---------HKKTQEDTSSPLSAAGQP 3770
+ V + V +L+ + D ++ W +K+++ T S SA
Sbjct: 2397 RITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTRTDS-YSAGQSV 2455
Query: 3771 ENMDSQQLVSLVQKAV-TAIMTRLHN 3795
E +D +L K T + +H+
Sbjct: 2456 EILDGVELGEPAHKKTGTTVPESIHS 2481
Score = 37.0 bits (84), Expect = 0.38
Identities = 54/272 (19%), Positives = 103/272 (37%), Gaps = 19/272 (6%)
Query: 2713 FYEQESITPPQQEILDSLAELYSLLQEEDMWAGLWQKRCKY--SETATAIAYEQHGFFEQ 2770
+ E E P IL+SL + + LQ+ + AG+ + K+ A YE+ +E
Sbjct: 1399 YKELEFQKGPTPAILESLISINNKLQQPEAAAGVLEYAMKHFGELEIQATWYEKLHEWED 1458
Query: 2771 AQESYEKAMDKAKKEHERSNASPAIFPEYQLWEDHWIRCSKELNQWEALTEYGQSKGHIN 2830
A +Y+K MD K + E W +C + +W + + Q+K
Sbjct: 1459 ALVAYDKKMDTNKDDPELMLGRMRCLEALGEWGQLHQQCCE---KWTLVNDETQAK---M 1512
Query: 2831 PYLVLECAWRVSNWTAMKEALVQVEVSCPKEMAWKVNMYRGYLAICHPEEQQLSFIERLV 2890
+ AW + W +M+E + P++ YR LA+ + S ++ +
Sbjct: 1513 ARMAAAAAWGLGQWDSMEEYTCMI----PRD-THDGAFYRAVLAL---HQDLFSLAQQCI 1564
Query: 2891 EMASSLAIREWRRLPHVVSHVHTPLLQAAQQIIELQEAAQINAGLQPTNLGRN---NSLH 2947
+ A L E + + + + EL+E Q + + R L
Sbjct: 1565 DKARDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLVPERREIIRQIWWERLQ 1624
Query: 2948 DMKTVVKTWRNRLPIVSDDLSHWSSIFMWRQH 2979
+ +V+ W+ L + S +S + W ++
Sbjct: 1625 GCQRIVEDWQKILMVRSLVVSPHEDMRTWLKY 1656
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 67.8 bits (164), Expect = 2e-10
Identities = 119/583 (20%), Positives = 220/583 (37%), Gaps = 105/583 (18%)
Query: 3197 VPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYK 3256
VP Q+++WI ++ L + + + + ++ YPQA+ +P I E Y
Sbjct: 3490 VPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPF--------IISSESYS 3541
Query: 3257 SDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLE--GIVDQMV----------WFRENWH 3304
++ + H +E + S L+ G++ + ++W
Sbjct: 3542 ------------FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWS 3589
Query: 3305 EEVLRQL------QQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN 3358
+V +L ++ + K Y + A+ D K P F +K + TFG +
Sbjct: 3590 NDVRAELAKTPVNKKNIEKMYERMY---AALGDPK-APGLGAFRRKFIQTFGKEFDK--- 3642
Query: 3359 VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKI 3418
F S+ L + LK + D PG++K + W+
Sbjct: 3643 ---HFGKGGSKLLRMKLSDFNDITNMLLLK----MNKDSKPPGNLK------ECSPWMS- 3688
Query: 3419 LEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFL---MPKPTHYYIKIARFMPRVE 3475
+ K FL N E+EIPG++ P P Y+++IA F RV
Sbjct: 3689 --------------DFKVEFLRN------ELEIPGQYDGRGKPLP-EYHVRIAGFDERVT 3727
Query: 3476 IVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK 3535
++ +R+ IRGH+ + +P+LV L R+++RV QL +++N L + ++
Sbjct: 3728 VMASLRRP-KRIIIRGHDEREHPFLVKGGEDL---RQDQRVEQLFQVMNGILAQDSACSQ 3783
Query: 3536 RHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQA 3595
R L R +V P + +P + YK K +HD + Y +
Sbjct: 3784 RALQL---RTYSVVP---MTSSDPRAPPCE--YKDWLTKMSGKHD--VGAYM-----LMY 3828
Query: 3596 RGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEF 3655
+G + V +E + VP +LK + + + R F ALI + +
Sbjct: 3829 KGANRTETVTSFRKRE---SKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHW 3885
Query: 3656 VLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGV 3715
+L + + +A +TG + F AT L +PFRLT + +
Sbjct: 3886 ILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKE 3945
Query: 3716 SGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQE 3758
+G + + M+ R F + + +++ W Q+
Sbjct: 3946 TGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQK 3988
>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
catalytic polypeptide [Homo sapiens]
Length = 4096
Score = 67.8 bits (164), Expect = 2e-10
Identities = 119/583 (20%), Positives = 220/583 (37%), Gaps = 105/583 (18%)
Query: 3197 VPPIQWLAWIPQLLTCLVGSEGKLLLNLISQVGRVYPQAVYFPIRTLYLTLKIEQRERYK 3256
VP Q+++WI ++ L + + + + ++ YPQA+ +P I E Y
Sbjct: 3489 VPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPF--------IISSESYS 3540
Query: 3257 SDPGPIRATAPMWRCSRIMHMQRELHPTLLSSLE--GIVDQMV----------WFRENWH 3304
++ + H +E + S L+ G++ + ++W
Sbjct: 3541 ------------FKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWS 3588
Query: 3305 EEVLRQL------QQGLAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSN 3358
+V +L ++ + K Y + A+ D K P F +K + TFG +
Sbjct: 3589 NDVRAELAKTPVNKKNIEKMYERMY---AALGDPK-APGLGAFRRKFIQTFGKEFDK--- 3641
Query: 3359 VSTMFSSAASESLARRAQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKI 3418
F S+ L + LK + D PG++K + W+
Sbjct: 3642 ---HFGKGGSKLLRMKLSDFNDITNMLLLK----MNKDSKPPGNLK------ECSPWMS- 3687
Query: 3419 LEAKTKQLPKFFLIEEKCRFLSNFSAQTAEVEIPGEFL---MPKPTHYYIKIARFMPRVE 3475
+ K FL N E+EIPG++ P P Y+++IA F RV
Sbjct: 3688 --------------DFKVEFLRN------ELEIPGQYDGRGKPLP-EYHVRIAGFDERVT 3726
Query: 3476 IVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK 3535
++ +R+ IRGH+ + +P+LV L R+++RV QL +++N L + ++
Sbjct: 3727 VMASLRRP-KRIIIRGHDEREHPFLVKGGEDL---RQDQRVEQLFQVMNGILAQDSACSQ 3782
Query: 3536 RHLFFTVPRVVAVSPQMRLVEDNPSSLSLVEIYKQRCAKKGIEHDNPISRYYDRLATVQA 3595
R L R +V P + +P + YK K +HD + Y +
Sbjct: 3783 RALQL---RTYSVVP---MTSSDPRAPPCE--YKDWLTKMSGKHD--VGAYM-----LMY 3827
Query: 3596 RGTQASHQVLRDILKEVQSNMVPRSMLKEWALHTFPNATDYWTFRKMFTIQLALIGFAEF 3655
+G + V +E + VP +LK + + + R F ALI + +
Sbjct: 3828 KGANRTETVTSFRKRE---SKVPADLLKRAFVRMSTSPEAFLALRSHFASSHALICISHW 3884
Query: 3656 VLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGV 3715
+L + + +A +TG + F AT L +PFRLT + +
Sbjct: 3885 ILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKE 3944
Query: 3716 SGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAWHKKTQE 3758
+G + + M+ R F + + +++ W Q+
Sbjct: 3945 TGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQK 3987
>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
Length = 3661
Score = 58.5 bits (140), Expect = 1e-07
Identities = 107/526 (20%), Positives = 213/526 (40%), Gaps = 76/526 (14%)
Query: 3272 SRIMHMQRELHPTLLSSLEGIVDQM----VWFRENW-------HEEVLRQLQQ------G 3314
S+I+ +PT++ ++ +V ++ V + E W H VLR++QQ
Sbjct: 1931 SKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKR 1990
Query: 3315 LAKCYSVAFEKSGAVSDAKITPHTLNFVKKLVSTFGVGLENVSNVSTMFSSAASESLARR 3374
+ ++ E+ A+ K T L+ LE+V +++ + E +
Sbjct: 1991 VQNNNTLRKEEKIAIMREKHTA--------LMKPIVFALEHVRSITAAPAETPHEKWFQD 2042
Query: 3375 AQATAQDPVFQKLKGQFTTDFDFSVPGSMKLHNLISKLKKWIKILEAKTKQLPKFFL-IE 3433
A + +KLK T + + PGS + K+ + L+ + ++ + L +E
Sbjct: 2043 NYGDAIENALEKLK----TPLNPAKPGSSWI-----PFKEIMLSLQQRAQKRASYILRLE 2093
Query: 3434 EKCRFLSNFSAQTAEVEIPGEFLMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHN 3493
E +L+ + E+ +PGE + + T + I + I+ T ++L G +
Sbjct: 2094 EISPWLAAMT--NTEIALPGE-VSARDT---VTIHSVGGTITILPT-KTKPKKLLFLGSD 2146
Query: 3494 GKIYPYLVMNDACLTESRREERVLQLLRLLNPCLE--KRKETTKRHL-FFTVPRVVAVSP 3550
GK YPYL L + +ER++Q L ++N R+ET + H ++V + S
Sbjct: 2147 GKSYPYLFKG---LEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSG 2203
Query: 3551 QMRLVEDNPSSLSLVEIYKQRCAKKGIEH--------------DNPISRYYDRLA----- 3591
++ V+ L + ++QR A + P YY ++
Sbjct: 2204 LIQWVDGATPLFGLYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKT 2263
Query: 3592 ---TVQARGTQASHQVLRDILKEVQSNMVPRSMLKE-WALHTFPNATDYWTFRKMFTIQL 3647
++ V++ +L+E+ P + KE W+ T P+ ++W + +
Sbjct: 2264 VGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPD--EWWRVTQSYARST 2321
Query: 3648 ALIGFAEFVLHLNRLNPEMLQIAQDTGKLNVAYFRFDINDATG-DLDANRPVPFRLTPNI 3706
A++ +++ L + + + I TG+ V + +++ G L VPFR+T NI
Sbjct: 2322 AVMSMVGYIIGLGDRHLDNVLIDMTTGE--VVHIDYNVCFEKGKSLRVPEKVPFRMTQNI 2379
Query: 3707 SEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKTVLRDEIIAW 3752
L GV G S V + + +L+ + D ++ W
Sbjct: 2380 ETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLLEAFVYDPLVDW 2425
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 57.0 bits (136), Expect = 4e-07
Identities = 23/42 (54%), Positives = 25/42 (59%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P PA P P P AP P+ PPPPP PPP P P+P PP
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP 1515
Score = 52.0 bits (123), Expect = 1e-05
Identities = 25/56 (44%), Positives = 29/56 (51%), Gaps = 13/56 (23%)
Query: 484 LPGVPTAPA-------------APGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
LPG+P+A + P P P+P P P PPPPPPPP PA P P V P
Sbjct: 1436 LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAP 1491
Score = 47.8 bits (112), Expect = 2e-04
Identities = 28/81 (34%), Positives = 34/81 (41%), Gaps = 5/81 (6%)
Query: 481 EAALPGVPTAPAAPGPAPSPAPVPAPPPP-----PPPPPPATPVTPAPVPPFEKQGEKDK 535
+ ALP P A +P P P+P PPPP PPPPPPA AP +D
Sbjct: 1479 QPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Query: 536 EDKQTFQVTDCRSLVKTLVCG 556
E T + + VCG
Sbjct: 1539 ELPDTRPLHLAKKQETAAVCG 1559
Score = 45.4 bits (106), Expect = 0.001
Identities = 27/67 (40%), Positives = 28/67 (41%), Gaps = 27/67 (40%)
Query: 486 GVPTAPAA--PGPAPSPA------------------PVPAPPP-------PPPPPPPATP 518
G P APAA PGP P P P P PPP PPPPPPP P
Sbjct: 1421 GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQP 1480
Query: 519 VTPAPVP 525
P+P P
Sbjct: 1481 ALPSPPP 1487
Score = 44.3 bits (103), Expect = 0.002
Identities = 25/62 (40%), Positives = 26/62 (41%), Gaps = 14/62 (22%)
Query: 479 AVEAALPGVPTAPAAPGP-------------APSPAPVPAPPPPP-PPPPPATPVTPAPV 524
A AA+PG P P P P P P PAP P P PPPPP P P
Sbjct: 1425 APAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS 1484
Query: 525 PP 526
PP
Sbjct: 1485 PP 1486
Score = 39.7 bits (91), Expect = 0.058
Identities = 18/40 (45%), Positives = 21/40 (52%), Gaps = 13/40 (32%)
Query: 493 APGPAPSPAPV-------------PAPPPPPPPPPPATPV 519
AP P+PS + V P PPPPPPPPPP P+
Sbjct: 809 APSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPL 848
Score = 37.0 bits (84), Expect = 0.38
Identities = 20/39 (51%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 475 SELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPP 513
S LG A GV PA GPA +P P PP PPPPP
Sbjct: 201 SSLGFERLAGGGV-LGPAGLGPAQTPPYRPGPPDPPPPP 238
Score = 36.6 bits (83), Expect = 0.49
Identities = 20/53 (37%), Positives = 25/53 (47%), Gaps = 5/53 (9%)
Query: 488 PTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAP-----VPPFEKQGEKDK 535
P APA P +P + PP P A P PAP + P EK+ EK+K
Sbjct: 1694 PKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEK 1746
Score = 35.8 bits (81), Expect = 0.84
Identities = 19/50 (38%), Positives = 20/50 (40%), Gaps = 13/50 (26%)
Query: 485 PGVPTAPAAPGPAPS-------------PAPVPAPPPPPPPPPPATPVTP 521
PG+ P P PS P PPPPPPPPPPA P
Sbjct: 1006 PGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 33.1 bits (74), Expect = 5.4
Identities = 13/22 (59%), Positives = 13/22 (59%)
Query: 491 PAAPGPAPSPAPVPAPPPPPPP 512
PA AP P P P PPPPP P
Sbjct: 826 PATRDGAPQPPPPPPPPPPPMP 847
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 56.6 bits (135), Expect = 5e-07
Identities = 23/39 (58%), Positives = 23/39 (58%)
Query: 488 PTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P A APGP P P P P PPPPPPPA P P P PP
Sbjct: 14 PGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPP 52
Score = 50.1 bits (118), Expect = 4e-05
Identities = 24/55 (43%), Positives = 26/55 (47%)
Query: 472 KPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
+P GA A P P PA P P P P PAPPP P P PP P +PP
Sbjct: 9 RPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPP 63
Score = 39.3 bits (90), Expect = 0.076
Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 3/69 (4%)
Query: 459 IARYQLSAIFKKCKPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPP--PPPPPA 516
IA Q +A C PQ V G P P P P+PA PPPP PP PA
Sbjct: 727 IATLQQAAAMSFC-PQVARPLVGPLALGSPRLVRRPPPGPAPAAASPGPPPPASPPGAPA 785
Query: 517 TPVTPAPVP 525
+P P P
Sbjct: 786 SPRAPRTSP 794
Score = 37.7 bits (86), Expect = 0.22
Identities = 15/32 (46%), Positives = 16/32 (50%)
Query: 495 GPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
G P +P P P PPPPPP P P PP
Sbjct: 7 GGRPGESPGATPAPGPPPPPPPAPPQQQPPPP 38
Score = 32.3 bits (72), Expect = 9.3
Identities = 14/34 (41%), Positives = 14/34 (41%)
Query: 493 APGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
A G P P P P PPPP P P PP
Sbjct: 3 ARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPP 36
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 56.2 bits (134), Expect = 6e-07
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 18/121 (14%)
Query: 423 LLNLVD-CI-RSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQ--------LSAIFKKCK 472
L +L+D C+ ++K E+ + + E F + A Q L A ++ +
Sbjct: 477 LTHLIDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRDEKIKELEAEIQQLR 536
Query: 473 PQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPP-------PPPPPPPPATPVTPAPVP 525
Q+++ + + +PG P AP PG P P P PAPP PPPPPP P P P P
Sbjct: 537 TQAQVLSSSSGIPGPPAAPPLPGVGPPPPP-PAPPLPGGAPLPPPPPPLPGMMGIPPPPP 595
Query: 526 P 526
P
Sbjct: 596 P 596
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 56.2 bits (134), Expect = 6e-07
Identities = 38/121 (31%), Positives = 56/121 (46%), Gaps = 18/121 (14%)
Query: 423 LLNLVD-CI-RSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQ--------LSAIFKKCK 472
L +L+D C+ ++K E+ + + E F + A Q L A ++ +
Sbjct: 477 LTHLIDSCVNKAKVEESEQKAAEFSKKFDEEFTARQEAQAELQKRDEKIKELEAEIQQLR 536
Query: 473 PQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPP-------PPPPPPPPATPVTPAPVP 525
Q+++ + + +PG P AP PG P P P PAPP PPPPPP P P P P
Sbjct: 537 TQAQVLSSSSGIPGPPAAPPLPGVGPPPPP-PAPPLPGGAPLPPPPPPLPGMMGIPPPPP 595
Query: 526 P 526
P
Sbjct: 596 P 596
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 55.8 bits (133), Expect = 8e-07
Identities = 44/152 (28%), Positives = 64/152 (42%), Gaps = 48/152 (31%)
Query: 417 TMSCKLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAI--------- 467
T+S LL++ D ++ K+++E+GNG +++ +LE + K A S++
Sbjct: 2288 TVSTDLLISEKDPVK-KAKKETGNG--IILEVLEAYRDKKELEAERTKSSLSETVFDHPP 2344
Query: 468 ----------------------FKKCKPQSELGAVEAALPGVPTAPAAPGP--------- 496
F + KP S+L + P V + PA P P
Sbjct: 2345 SSVIALPMKEQLSTTYFTSGETFGQEKPASQL---PSGSPSVSSLPAKPRPFFRSSSLDI 2401
Query: 497 --APSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P P P PPPPPPPPPP P P P P
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 38.9 bits (89), Expect = 0.099
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 464 LSAIFKKCKPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT 517
+S++ K +P +++ + P P P P P P P P PP PPP P T
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPT 2436
Score = 35.8 bits (81), Expect = 0.84
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 472 KPQSELGAVEAALPGVPTAPAAPGPAPSPA---PVPAPPPPPPP---PPPATPVTPAPVP 525
KP ++ E + PG PA P P P PP PP PPA P+ PA P
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK-P 371
Query: 526 PFEKQGEKDKEDKQ 539
P ++ G + +Q
Sbjct: 372 PAQQTGSEKPSSEQ 385
Score = 33.5 bits (75), Expect = 4.2
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 4/60 (6%)
Query: 482 AALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT---PVTPAPVPPFEKQGEKDKEDK 538
A PG P + + PG AP P+ PP PP +T P PA P +K+ + +K
Sbjct: 949 AGQPG-PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Score = 33.5 bits (75), Expect = 4.2
Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 6/44 (13%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPPPP------ATPVTPA 522
P P P P P P P P+P P P P P A+PVT A
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA 2452
Score = 33.1 bits (74), Expect = 5.4
Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 4/60 (6%)
Query: 484 LPG-VPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT---PVTPAPVPPFEKQGEKDKEDKQ 539
LPG P PGPA P P PP P +T P P P P +Q K Q
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Score = 32.3 bits (72), Expect = 9.3
Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 5/63 (7%)
Query: 481 EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPP-PATPVTPAP---VPPFEKQGEKDKE 536
+ A PG T+ GP P+ +P P PPP P PA P P PP ++ G
Sbjct: 452 QQAGPG-KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 537 DKQ 539
+Q
Sbjct: 511 PQQ 513
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 55.8 bits (133), Expect = 8e-07
Identities = 44/152 (28%), Positives = 64/152 (42%), Gaps = 48/152 (31%)
Query: 417 TMSCKLLLNLVDCIRSKSEQESGNGRDVLMRMLEVFVLKFHTIARYQLSAI--------- 467
T+S LL++ D ++ K+++E+GNG +++ +LE + K A S++
Sbjct: 2288 TVSTDLLISEKDPVK-KAKKETGNG--IILEVLEAYRDKKELEAERTKSSLSETVFDHPP 2344
Query: 468 ----------------------FKKCKPQSELGAVEAALPGVPTAPAAPGP--------- 496
F + KP S+L + P V + PA P P
Sbjct: 2345 SSVIALPMKEQLSTTYFTSGETFGQEKPASQL---PSGSPSVSSLPAKPRPFFRSSSLDI 2401
Query: 497 --APSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P P P PPPPPPPPPP P P P P
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Score = 38.9 bits (89), Expect = 0.099
Identities = 18/54 (33%), Positives = 26/54 (48%)
Query: 464 LSAIFKKCKPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT 517
+S++ K +P +++ + P P P P P P P P PP PPP P T
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPT 2436
Score = 35.8 bits (81), Expect = 0.84
Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 7/74 (9%)
Query: 472 KPQSELGAVEAALPGVPTAPAAPGPAPSPA---PVPAPPPPPPP---PPPATPVTPAPVP 525
KP ++ E + PG PA P P P PP PP PPA P+ PA P
Sbjct: 313 KPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAK-P 371
Query: 526 PFEKQGEKDKEDKQ 539
P ++ G + +Q
Sbjct: 372 PAQQTGSEKPSSEQ 385
Score = 33.5 bits (75), Expect = 4.2
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 4/60 (6%)
Query: 482 AALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT---PVTPAPVPPFEKQGEKDKEDK 538
A PG P + + PG AP P+ PP PP +T P PA P +K+ + +K
Sbjct: 949 AGQPG-PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Score = 33.5 bits (75), Expect = 4.2
Identities = 18/44 (40%), Positives = 20/44 (45%), Gaps = 6/44 (13%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPPPP------ATPVTPA 522
P P P P P P P P+P P P P P A+PVT A
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA 2452
Score = 33.1 bits (74), Expect = 5.4
Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 4/60 (6%)
Query: 484 LPG-VPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT---PVTPAPVPPFEKQGEKDKEDKQ 539
LPG P PGPA P P PP P +T P P P P +Q K Q
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Score = 32.3 bits (72), Expect = 9.3
Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 5/63 (7%)
Query: 481 EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPP-PATPVTPAP---VPPFEKQGEKDKE 536
+ A PG T+ GP P+ +P P PPP P PA P P PP ++ G
Sbjct: 452 QQAGPG-KTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP 510
Query: 537 DKQ 539
+Q
Sbjct: 511 PQQ 513
>gi|158534059 formin binding protein 4 [Homo sapiens]
Length = 1017
Score = 55.1 bits (131), Expect = 1e-06
Identities = 32/76 (42%), Positives = 38/76 (50%), Gaps = 8/76 (10%)
Query: 481 EAALPGVPTAPA-----APGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDK 535
E ++P TAP+ A G P+ + PPPPPPPPPP P P P K+G KDK
Sbjct: 876 ECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDK 935
Query: 536 EDKQTFQVTDCRSLVK 551
K T SLVK
Sbjct: 936 AKKSK---TKMPSLVK 948
Score = 44.3 bits (103), Expect = 0.002
Identities = 17/31 (54%), Positives = 20/31 (64%)
Query: 502 PVPAPPPPPPPPPPATPVTPAPVPPFEKQGE 532
P+P PPPPPPPP +P P P PP + GE
Sbjct: 706 PLPLEMPPPPPPPPESPPPPPPPPPPAEDGE 736
Score = 42.0 bits (97), Expect = 0.012
Identities = 15/21 (71%), Positives = 16/21 (76%)
Query: 496 PAPSPAPVPAPPPPPPPPPPA 516
P P P P +PPPPPPPPPPA
Sbjct: 712 PPPPPPPPESPPPPPPPPPPA 732
Score = 41.2 bits (95), Expect = 0.020
Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 3/49 (6%)
Query: 491 PAAPGPAPSPAPVPAPPPP---PPPPPPATPVTPAPVPPFEKQGEKDKE 536
P P P P P PPPP PPPPPP P + E + E +E
Sbjct: 701 PVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEE 749
Score = 39.3 bits (90), Expect = 0.076
Identities = 15/27 (55%), Positives = 15/27 (55%)
Query: 488 PTAPAAPGPAPSPAPVPAPPPPPPPPP 514
P P P P P P PPPPPPPPP
Sbjct: 705 PPLPLEMPPPPPPPPESPPPPPPPPPP 731
Score = 34.3 bits (77), Expect = 2.4
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPP 511
P +P P P P +P P PPPPPP
Sbjct: 705 PPLPLEMPPPPPPPPESPPPPPPPPPP 731
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 54.7 bits (130), Expect = 2e-06
Identities = 32/74 (43%), Positives = 40/74 (54%), Gaps = 6/74 (8%)
Query: 466 AIFKKCKPQSELGAVEAALPGVPTAPAAPGPAPS-PAPVPAPPPP--PPPPPPATPVTPA 522
A+ ++ P +E EA LP P P AP P P P P +PPPP PPPPPP +P P
Sbjct: 385 AVAEEMMPAAE--KEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSP-PPL 441
Query: 523 PVPPFEKQGEKDKE 536
P PP E+ +E
Sbjct: 442 PSPPPPPAQEEQEE 455
Score = 46.2 bits (108), Expect = 6e-04
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
Query: 469 KKCKPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPP----------PPPATP 518
K+ + + E E +P A P P P P+PPPP PP PPP P
Sbjct: 376 KEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPP 435
Query: 519 VTPAPVP-PFEKQGEKDKED 537
V+P P+P P ++++E+
Sbjct: 436 VSPPPLPSPPPPPAQEEQEE 455
Score = 43.9 bits (102), Expect = 0.003
Identities = 23/64 (35%), Positives = 23/64 (35%), Gaps = 25/64 (39%)
Query: 488 PTAPAAPGPAPSPAPVPAPPPPP-------------------------PPPPPATPVTPA 522
P P P P PSP P PP P PPPPPA P PA
Sbjct: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA 630
Query: 523 PVPP 526
P PP
Sbjct: 631 PSPP 634
Score = 42.7 bits (99), Expect = 0.007
Identities = 22/61 (36%), Positives = 24/61 (39%), Gaps = 20/61 (32%)
Query: 485 PGVPTAPAAPGPAPS--------------------PAPVPAPPPPPPPPPPATPVTPAPV 524
P PT P+ P P P P P PAPPPPP P PP P T +
Sbjct: 584 PRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRR 643
Query: 525 P 525
P
Sbjct: 644 P 644
Score = 38.1 bits (87), Expect = 0.17
Identities = 18/43 (41%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPPP--PATPVTPAPVP 525
P V +P P + PVP P P P PP P P TP P+P
Sbjct: 555 PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597
Score = 36.6 bits (83), Expect = 0.49
Identities = 15/33 (45%), Positives = 16/33 (48%)
Query: 488 PTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVT 520
P P +P P PSP P PA PPP P T
Sbjct: 432 PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
Score = 35.0 bits (79), Expect = 1.4
Identities = 21/47 (44%), Positives = 22/47 (46%), Gaps = 9/47 (19%)
Query: 488 PTAPAA----PGPAPSPAPV-----PAPPPPPPPPPPATPVTPAPVP 525
PTAP + PGP PV PAPPPPPPP PA P
Sbjct: 2226 PTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPP 2272
Score = 34.3 bits (77), Expect = 2.4
Identities = 23/66 (34%), Positives = 23/66 (34%), Gaps = 24/66 (36%)
Query: 484 LPGVPTAPAAPGPAPSPAPVPAPPPPPP-----------------------PPPPATPVT 520
LP P AP P PAPSP P PA P PPP P
Sbjct: 618 LPPPPPAPPPP-PAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEA 676
Query: 521 PAPVPP 526
P P PP
Sbjct: 677 PEPEPP 682
>gi|4557329 fas ligand [Homo sapiens]
Length = 281
Score = 54.3 bits (129), Expect = 2e-06
Identities = 26/59 (44%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 473 PQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQG 531
P + G V VP P P P P P P PPPPPPPP P P P+PP +K+G
Sbjct: 22 PWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPPPLP-----PLPLPPLKKRG 75
Score = 38.9 bits (89), Expect = 0.099
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 489 TAPAAPGPAPSPAPVPAPPPP----PPPPPPATPVTPAPVPP 526
++P AP P P P P PPPPPP P+ P P PP
Sbjct: 20 SSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPP 61
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 53.9 bits (128), Expect = 3e-06
Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 3/69 (4%)
Query: 485 PGVPTAPAAPGPAPSPAPV---PAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQTF 541
P P P P P P P+ P PPPPPPPPPP V P+ +K+ K+D+
Sbjct: 45 PPPPPPPQLPQPPPQAQPLLPQPQPPPPPPPPPPGPAVAEEPLHRPKKELSATKKDRVNH 104
Query: 542 QVTDCRSLV 550
+T C ++V
Sbjct: 105 CLTICENIV 113
Score = 40.8 bits (94), Expect = 0.026
Identities = 16/29 (55%), Positives = 17/29 (58%)
Query: 498 PSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P P P PP P PPP A P+ P P PP
Sbjct: 42 PPPPPPPPPPQLPQPPPQAQPLLPQPQPP 70
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 53.5 bits (127), Expect = 4e-06
Identities = 29/69 (42%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 464 LSAIFKKCKPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPP-PAT-PVTP 521
L A + + S+ G V L P P PGPA + +P PP PPPPPP P+T P P
Sbjct: 291 LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP 350
Query: 522 APVPPFEKQ 530
P PP Q
Sbjct: 351 PPPPPLPNQ 359
Score = 50.1 bits (118), Expect = 4e-05
Identities = 25/50 (50%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
Query: 483 ALPGVPTAPAAPGPAPSPAPVPAPPPPP-----PPPPPATPVTPAPVPPF 527
ALP P P P P PS P P PPPPP PPPPP P P P F
Sbjct: 329 ALPP-PPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGF 377
Score = 47.4 bits (111), Expect = 3e-04
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 478 GAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVP 525
G +A++ +P P P P P P+ P PPPPPPP P P P P P
Sbjct: 322 GPAQASV-ALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368
Score = 38.9 bits (89), Expect = 0.099
Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 13/69 (18%)
Query: 475 SELGAVEAALPGVPTAPAAPGPAPSP-----APVPAPPPPPPPPPPAT-------PVTPA 522
S LG A+ PG+ A + P PS P+ PPPPP PP PA P P
Sbjct: 279 SVLGDSSASEPGLQAA-SQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPP 337
Query: 523 PVPPFEKQG 531
P PP G
Sbjct: 338 PPPPLPSTG 346
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 53.5 bits (127), Expect = 4e-06
Identities = 29/69 (42%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 464 LSAIFKKCKPQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPP-PAT-PVTP 521
L A + + S+ G V L P P PGPA + +P PP PPPPPP P+T P P
Sbjct: 291 LQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPP 350
Query: 522 APVPPFEKQ 530
P PP Q
Sbjct: 351 PPPPPLPNQ 359
Score = 50.1 bits (118), Expect = 4e-05
Identities = 25/50 (50%), Positives = 25/50 (50%), Gaps = 6/50 (12%)
Query: 483 ALPGVPTAPAAPGPAPSPAPVPAPPPPP-----PPPPPATPVTPAPVPPF 527
ALP P P P P PS P P PPPPP PPPPP P P P F
Sbjct: 329 ALPP-PPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASGF 377
Score = 47.4 bits (111), Expect = 3e-04
Identities = 21/48 (43%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 478 GAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVP 525
G +A++ +P P P P P P+ P PPPPPPP P P P P P
Sbjct: 322 GPAQASV-ALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPPPP 368
Score = 38.9 bits (89), Expect = 0.099
Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 13/69 (18%)
Query: 475 SELGAVEAALPGVPTAPAAPGPAPSP-----APVPAPPPPPPPPPPAT-------PVTPA 522
S LG A+ PG+ A + P PS P+ PPPPP PP PA P P
Sbjct: 279 SVLGDSSASEPGLQAA-SQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPP 337
Query: 523 PVPPFEKQG 531
P PP G
Sbjct: 338 PPPPLPSTG 346
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 53.1 bits (126), Expect = 5e-06
Identities = 25/49 (51%), Positives = 28/49 (57%), Gaps = 2/49 (4%)
Query: 480 VEAALPGVPTAPAAPGPAPSPAPVPAPPP--PPPPPPPATPVTPAPVPP 526
+ A LP P P P PA P PPP PPPPPPPA+P+ P P PP
Sbjct: 320 ISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPP 368
Score = 50.4 bits (119), Expect = 3e-05
Identities = 25/46 (54%), Positives = 27/46 (58%), Gaps = 5/46 (10%)
Query: 485 PGVPTAPAA-PGPAPSPAPVPAPP----PPPPPPPPATPVTPAPVP 525
P P PAA P P PSP P P PP PPPPPPPP TP + +P
Sbjct: 334 PLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPPPPTPSSTTKLP 379
Score = 48.1 bits (113), Expect = 2e-04
Identities = 21/40 (52%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 488 PTAPAAPGP-APSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P P P A P P P+PPPPPPPP P P P PP
Sbjct: 331 PPRPLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPPPP 370
Score = 47.0 bits (110), Expect = 4e-04
Identities = 21/43 (48%), Positives = 22/43 (51%), Gaps = 5/43 (11%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPP-----PPPPATPVTPA 522
P P P P P P P P PPPPPP PPPP P TP+
Sbjct: 331 PPRPLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPPPPTPS 373
Score = 39.3 bits (90), Expect = 0.076
Identities = 17/36 (47%), Positives = 19/36 (52%)
Query: 482 AALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT 517
AA P P +P P P P+ P PPPPPP P T
Sbjct: 341 AAQPRPPPSPPPPPPPPASPLPPPPPPPPPTPSSTT 376
>gi|149944526 additional sex combs like 3 [Homo sapiens]
Length = 2248
Score = 53.1 bits (126), Expect = 5e-06
Identities = 36/165 (21%), Positives = 73/165 (44%), Gaps = 8/165 (4%)
Query: 472 KPQSELGAVEAALPGVPTA-PAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQ 530
K E+G +P P P P P P P+ PPPPPPPPP P+ A VP +KQ
Sbjct: 1997 KEGDEVGGTAHTMPNKALVHPPPPPPPPPPPPLALPPPPPPPPPLPPPLPNAEVPSDQKQ 2056
Query: 531 GEKDKEDKQTFQVTDCRSLVKTLVCGVKTITWGITSCKAPGEAQFIPNKQLQPKETQIYI 590
E + + + + G++S G KQ+ + ++
Sbjct: 2057 PPVTMETTKRLSWPQSTGICSNIKSEPLSFEEGLSSSCELG------MKQVSYDQNEMKE 2110
Query: 591 KLVKYAMQALDIYQVQIAGNGQTYIRVANCQTVRMKEEKEVLEHF 635
+L +A+++ D ++ + + ++A Q +++++++++ ++
Sbjct: 2111 QLKAFALKSADFSSYLLSEPQKPFTQLA-AQKMQVQQQQQLCGNY 2154
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 52.4 bits (124), Expect = 9e-06
Identities = 22/40 (55%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPP-PPPPPPPPATPVTPAP 523
P P AP++ +PSP+P + P PPPPPPPPA P PAP
Sbjct: 184 PAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAP 223
Score = 45.1 bits (105), Expect = 0.001
Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 1/42 (2%)
Query: 486 GVPTAPAAPGPAPS-PAPVPAPPPPPPPPPPATPVTPAPVPP 526
G P P AP A S P+P P+ P PPPPP P PAP P
Sbjct: 182 GGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAP 223
Score = 32.7 bits (73), Expect = 7.1
Identities = 22/93 (23%), Positives = 37/93 (39%), Gaps = 26/93 (27%)
Query: 473 PQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPP---------------PPPPPP-- 515
P + A + P ++ +P P P P PAPP P PPP P
Sbjct: 187 PPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQ 246
Query: 516 ---------ATPVTPAPVPPFEKQGEKDKEDKQ 539
+ P + A P E++ E+++E+++
Sbjct: 247 KYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEE 279
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 52.4 bits (124), Expect = 9e-06
Identities = 25/44 (56%), Positives = 26/44 (59%), Gaps = 4/44 (9%)
Query: 484 LPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPAT-PVTPAPVPP 526
LPG P P AP P P +P PPPPPPPPP PV P P PP
Sbjct: 568 LPGSPEPPPAP---PLPGDLPPPPPPPPPPPGTDGPVPPPPPPP 608
Score = 49.7 bits (117), Expect = 6e-05
Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 1/46 (2%)
Query: 481 EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
+A PGVPT +P AP+ P P PPPPPP P P +P PP
Sbjct: 515 DAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLP-SPQEAPP 559
Score = 49.3 bits (116), Expect = 7e-05
Identities = 27/69 (39%), Positives = 32/69 (46%), Gaps = 11/69 (15%)
Query: 479 AVEAALPGVPTAPAAPGPAPSPA------PVPAPPPPP-----PPPPPATPVTPAPVPPF 527
A +A P P P +P P P+P P P PPPPP P PPP P P P P
Sbjct: 557 APPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616
Query: 528 EKQGEKDKE 536
+ G +D E
Sbjct: 617 DALGRRDSE 625
Score = 48.5 bits (114), Expect = 1e-04
Identities = 28/56 (50%), Positives = 30/56 (53%), Gaps = 13/56 (23%)
Query: 484 LPGVPTAPAAPGPAP--------SPAPVPAPPPP---PPPPPPATPV--TPAPVPP 526
LPG+P+ AP AP SP P PAPP P PPPPPP P T PVPP
Sbjct: 548 LPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPP 603
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 52.0 bits (123), Expect = 1e-05
Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 11/99 (11%)
Query: 467 IFKKCKPQ-SELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVP 525
+F++ + Q ++ + E G P P P+PSP+PVPAP PPP PP PA AP+
Sbjct: 247 VFREAQKQVKKIDSCERRFLGGPARP----PSPSPSPVPAPAPPPGPPRPAAAAATAPL- 301
Query: 526 PFEKQGEKDKEDKQTFQVTDCRSLVKTL--VCGVKTITW 562
G K + +KTL + GV T+ W
Sbjct: 302 ---ANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCW 337
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 52.0 bits (123), Expect = 1e-05
Identities = 22/46 (47%), Positives = 22/46 (47%)
Query: 481 EAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
E G T P P P P P P P PPPPPPPP P P PP
Sbjct: 541 ETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPP 586
Score = 47.8 bits (112), Expect = 2e-04
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 6/46 (13%)
Query: 485 PGVPTAPAAP-----GPAPSPAPVPAPPPPPPPPPPATPVTPAPVP 525
P +P + P GP P P P PPPPPPPPPP P P P+P
Sbjct: 531 PPLPPSSDTPETVQNGPVTPPMP-PPPPPPPPPPPPPPPPPPPPLP 575
Score = 46.6 bits (109), Expect = 5e-04
Identities = 24/61 (39%), Positives = 27/61 (44%), Gaps = 13/61 (21%)
Query: 479 AVEAALPGVPTAPAAPGPAPSP-----------APV--PAPPPPPPPPPPATPVTPAPVP 525
+V + + P P P P P PV P PPPPPPPPPP P P P P
Sbjct: 513 SVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPP 572
Query: 526 P 526
P
Sbjct: 573 P 573
Score = 46.2 bits (108), Expect = 6e-04
Identities = 21/40 (52%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 489 TAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFE 528
T P P P P P PPPPPPPPPP P P P P E
Sbjct: 542 TVQNGPVTPPMPPP-PPPPPPPPPPPPPPPPPPLPGPAAE 580
Score = 44.7 bits (104), Expect = 0.002
Identities = 19/39 (48%), Positives = 20/39 (51%)
Query: 488 PTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P P P P P P P PPPPP P P A V P+ P
Sbjct: 551 PMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAP 589
Score = 42.7 bits (99), Expect = 0.007
Identities = 22/53 (41%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
Query: 477 LGAVEAALPGVPTAPAAPGPAPSPAPV---PAPPPPPPPPPPATPVTPAPVPP 526
+GA + P P P P + +P V P PP PPPPPP P P P PP
Sbjct: 518 MGAASSG-PLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPP 569
Score = 42.0 bits (97), Expect = 0.012
Identities = 21/57 (36%), Positives = 22/57 (38%), Gaps = 15/57 (26%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPP---------------PPPPATPVTPAPVPP 526
P P P P P P P P P PPPPPP PP P+ P P P
Sbjct: 547 PVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSP 603
Score = 38.9 bits (89), Expect = 0.099
Identities = 51/235 (21%), Positives = 85/235 (36%), Gaps = 52/235 (22%)
Query: 330 ELLIAAKHILTTELRNQFIPCMDKLFDESILIGSGYTARETLRPLAYSTLADLVHHVRQH 389
E L KH + +L+ Q +D +FD L+ T L + L + + H+ +
Sbjct: 351 EYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERV--EELEENISHLSEK 408
Query: 390 LPLSD-------LSLAVQLFAKNIDDESLPSSIQTMSCKL--LLNLVDCIRSKSEQESGN 440
L ++ + L QL +N + + + + + ++ L +V K ++E+
Sbjct: 409 LQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMV-----KEKEEAIQ 463
Query: 441 GRDVLMRMLEVFVLKFHTIARYQLSAIFKKCKPQSELGAVEAA---------LPGVPTAP 491
+ L + K H + + I KK + V A+ + G P
Sbjct: 464 RQSTLEK-------KIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGP 516
Query: 492 AAPGPAPSPAPVPAPP--------------------PPPPPPPPATPVTPAPVPP 526
+ P P P PP PPPPPPPP P P P PP
Sbjct: 517 TMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPP 571
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 52.0 bits (123), Expect = 1e-05
Identities = 20/39 (51%), Positives = 23/39 (58%)
Query: 487 VPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVP 525
+P + P AP P P P PPPPPPPPPP P P+ P
Sbjct: 1982 IPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPP 2020
Score = 51.6 bits (122), Expect = 1e-05
Identities = 24/57 (42%), Positives = 28/57 (49%), Gaps = 10/57 (17%)
Query: 484 LPGVPTAPAAPGPAP----------SPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQ 530
LP P P++ GP +P P P PPPPPPPPPP P P P P + Q
Sbjct: 1967 LPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQ 2023
Score = 48.9 bits (115), Expect = 1e-04
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 23/71 (32%)
Query: 479 AVEAALPGVPTAPAAPGPAPSPAPVP-----------------------APPPPPPPPPP 515
A + P P++P P P P P P+P APPP PPPPPP
Sbjct: 1943 AYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPP 2002
Query: 516 ATPVTPAPVPP 526
P P P PP
Sbjct: 2003 PPPPPPPPPPP 2013
Score = 48.5 bits (114), Expect = 1e-04
Identities = 20/35 (57%), Positives = 20/35 (57%)
Query: 490 APAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPV 524
AP P P P P P PPPPPPPPP A P PV
Sbjct: 1992 APPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPV 2026
Score = 43.9 bits (102), Expect = 0.003
Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 11/66 (16%)
Query: 482 AALPGVPT-APAAPGPAPSPAPV------PAPPPPPPPPPPATPVTPAPVPPFEKQGEKD 534
A + G PT A ++P + S AP P PPPPPPPPPP++ ++ +Q K+
Sbjct: 3088 AGMLGFPTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQT----EQQNKE 3143
Query: 535 KEDKQT 540
E KQT
Sbjct: 3144 SEKKQT 3149
Score = 42.0 bits (97), Expect = 0.012
Identities = 19/48 (39%), Positives = 20/48 (41%)
Query: 480 VEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPF 527
V L P P P P P P P P PPPPP PP +P F
Sbjct: 1986 VSTPLQAPPPTPPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLF 2033
Score = 35.4 bits (80), Expect = 1.1
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 3/48 (6%)
Query: 473 PQSELGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVT 520
P + ++A P P P P P P P P PPPP PP PV+
Sbjct: 1983 PNTVSTPLQAPPPTPPPPPPPPPPPPPPPP---PPPPSAPPQVQLPVS 2027
Score = 32.7 bits (73), Expect = 7.1
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 4/69 (5%)
Query: 467 IFKKCKPQSELGAVE-AALPGVPTAPAAPGPA-PSPAPVPAPPPPPPPPPPATPVTPAPV 524
++K C + A + AA P + P PSP P P P P P P P
Sbjct: 2315 VYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPS 2374
Query: 525 PPFEKQGEK 533
PP QG K
Sbjct: 2375 PP--SQGTK 2381
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 52.0 bits (123), Expect = 1e-05
Identities = 23/45 (51%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPP---PPPPPPPATPVTPAPVPP 526
PG P P P P P P PPP PPPPPPPA P P PP
Sbjct: 685 PGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPP 729
Score = 47.0 bits (110), Expect = 4e-04
Identities = 21/43 (48%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 485 PGVPTAPAAPG-PAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P P PG P P P P P PPPPP P P P P PP
Sbjct: 692 PPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPP 734
Score = 45.8 bits (107), Expect = 8e-04
Identities = 25/61 (40%), Positives = 26/61 (42%), Gaps = 12/61 (19%)
Query: 477 LGAVEAALPGVPTAPAAPGP------------APSPAPVPAPPPPPPPPPPATPVTPAPV 524
LG LPG P P P A PAP P PP PPPPPP PV P +
Sbjct: 1502 LGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKL 1561
Query: 525 P 525
P
Sbjct: 1562 P 1562
Score = 45.4 bits (106), Expect = 0.001
Identities = 24/48 (50%), Positives = 25/48 (52%), Gaps = 5/48 (10%)
Query: 485 PGVPTAPAAPGPAPSPAPV-PAP--PPPPPPPPPATPVTP--APVPPF 527
PG P P P P P P P PA PPPP P PP P P P+PPF
Sbjct: 701 PGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPF 748
Score = 42.7 bits (99), Expect = 0.007
Identities = 26/61 (42%), Positives = 32/61 (52%), Gaps = 7/61 (11%)
Query: 473 PQSELGAVEAALPGVPTAPAAPGPAPSP-AP-VPAPPPP-----PPPPPPATPVTPAPVP 525
P + + + + P V T AA APS AP +P PPPP PPPPPP P P+P
Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMP 706
Query: 526 P 526
P
Sbjct: 707 P 707
Score = 41.6 bits (96), Expect = 0.015
Identities = 20/43 (46%), Positives = 21/43 (48%), Gaps = 2/43 (4%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPP--PPATPVTPAPVP 525
P P PA P P P+PAPP PPPP PP P P P
Sbjct: 712 PPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFP 754
Score = 36.6 bits (83), Expect = 0.49
Identities = 24/68 (35%), Positives = 26/68 (38%), Gaps = 5/68 (7%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPPFEKQGEKDKEDKQTFQVT 544
P P P P P P P PP PPP P T + VPP E ED
Sbjct: 1268 PEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPP-----EPLAEDHPPHTPG 1322
Query: 545 DCRSLVKT 552
C SL K+
Sbjct: 1323 LCGSLAKS 1330
Score = 33.9 bits (76), Expect = 3.2
Identities = 17/38 (44%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPP---PPPPPPPPATPV 519
P P P P P+P VP PP P PP PP PV
Sbjct: 718 PAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPV 755
Score = 32.3 bits (72), Expect = 9.3
Identities = 22/49 (44%), Positives = 22/49 (44%), Gaps = 9/49 (18%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPPP-------PPATPVTPAPVPP 526
P PTA AA G S AP PPP PP P TP P P PP
Sbjct: 411 PEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTP--PGPPPP 457
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 51.6 bits (122), Expect = 1e-05
Identities = 26/50 (52%), Positives = 27/50 (54%), Gaps = 6/50 (12%)
Query: 477 LGAVEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
LGA AAL P P P PA PPPPPPPPPPA+ PA PP
Sbjct: 60 LGAAAAALL------LHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPP 103
Score = 39.7 bits (91), Expect = 0.058
Identities = 23/69 (33%), Positives = 26/69 (37%), Gaps = 7/69 (10%)
Query: 464 LSAIFKKCKPQSELGAVEAALPGVPTAPAAPGPA-------PSPAPVPAPPPPPPPPPPA 516
+S + P G+ A PG G A P P P PA PPPPPPP
Sbjct: 30 VSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPP 89
Query: 517 TPVTPAPVP 525
P A P
Sbjct: 90 PPPASAAAP 98
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 51.2 bits (121), Expect = 2e-05
Identities = 22/40 (55%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 488 PTAPAAPGP-APSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
P P P P A P P P+PPPPPPPPP P P P PP
Sbjct: 265 PPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPPPPPP 304
Score = 50.4 bits (119), Expect = 3e-05
Identities = 23/46 (50%), Positives = 26/46 (56%), Gaps = 5/46 (10%)
Query: 485 PGVPTAPAA-----PGPAPSPAPVPAPPPPPPPPPPATPVTPAPVP 525
P P PAA P P P P P P+P PPPPPPPP TP + +P
Sbjct: 268 PLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPPPPPPTPSSTTKLP 313
Score = 47.8 bits (112), Expect = 2e-04
Identities = 21/42 (50%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 485 PGVPTAPAAPGPAPSPAPVPAPPPPPPP---PPPATPVTPAP 523
P P P P P P P P PPPPPPP PPP P P P
Sbjct: 265 PPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPPPPPPTP 306
Score = 47.4 bits (111), Expect = 3e-04
Identities = 23/47 (48%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 480 VEAALPGVPTAPAAPGPAPSPAPVPAPPPPPPPPPPATPVTPAPVPP 526
+ A LP P P P PA P PPP PPPPPP P +P P PP
Sbjct: 254 LSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPPPP-SPLPPPP 299
Score = 33.9 bits (76), Expect = 3.2
Identities = 14/32 (43%), Positives = 16/32 (50%)
Query: 479 AVEAALPGVPTAPAAPGPAPSPAPVPAPPPPP 510
A + P P P P P+P P P P PPP P
Sbjct: 275 AAQPRPPPSPPPPPPPPPSPLPPPPPPPPPTP 306
Score = 32.7 bits (73), Expect = 7.1
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 8/58 (13%)
Query: 477 LGAVEAALPGVPTAPAAPGPAPSPAPVPA------PPPPPP--PPPPATPVTPAPVPP 526
L +++A P PT P P P+ A PPP P P PPA P P PP
Sbjct: 228 LRMIQSATPPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSPP 285
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141,147,558
Number of Sequences: 37866
Number of extensions: 6505706
Number of successful extensions: 92299
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 834
Number of HSP's successfully gapped in prelim test: 399
Number of HSP's that attempted gapping in prelim test: 45899
Number of HSP's gapped (non-prelim): 25336
length of query: 3830
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3708
effective length of database: 13,627,866
effective search space: 50532127128
effective search space used: 50532127128
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.