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Search of human proteins with 4507677
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507677 heat shock protein 90kDa beta, member 1 [Homo
sapiens]
(803 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens] 1588 0.0
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens] 657 0.0
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s... 639 0.0
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s... 639 0.0
gi|155722983 TNF receptor-associated protein 1 [Homo sapiens] 325 1e-88
gi|17975763 myelin transcription factor 1 [Homo sapiens] 46 2e-04
gi|71061468 centromere protein E [Homo sapiens] 45 2e-04
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 45 2e-04
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 45 3e-04
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 45 3e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 5e-04
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 44 5e-04
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens] 44 5e-04
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens] 44 5e-04
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 44 6e-04
gi|215422388 death-domain associated protein isoform a [Homo sap... 44 6e-04
gi|215422366 death-domain associated protein isoform b [Homo sap... 44 6e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 6e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 44 6e-04
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 44 8e-04
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 43 0.001
gi|21361639 DIPB protein [Homo sapiens] 43 0.001
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 43 0.001
gi|21735415 centromere protein B [Homo sapiens] 42 0.002
gi|4757900 calreticulin precursor [Homo sapiens] 42 0.002
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 42 0.002
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 42 0.002
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 42 0.002
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 42 0.002
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 42 0.002
>gi|4507677 heat shock protein 90kDa beta, member 1 [Homo sapiens]
Length = 803
Score = 1588 bits (4112), Expect = 0.0
Identities = 803/803 (100%), Positives = 803/803 (100%)
Query: 1 MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDG 60
MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDG
Sbjct: 1 MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDG 60
Query: 61 LNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISL 120
LNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISL
Sbjct: 61 LNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISL 120
Query: 121 TDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTE 180
TDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTE
Sbjct: 121 TDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTE 180
Query: 181 AQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNT 240
AQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNT
Sbjct: 181 AQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNT 240
Query: 241 LGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAK 300
LGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAK
Sbjct: 241 LGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAK 300
Query: 301 EEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYK 360
EEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYK
Sbjct: 301 EEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYK 360
Query: 361 SFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITD 420
SFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITD
Sbjct: 361 SFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITD 420
Query: 421 DFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKY 480
DFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKY
Sbjct: 421 DFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKY 480
Query: 481 NDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYF 540
NDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYF
Sbjct: 481 NDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYF 540
Query: 541 MAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDE 600
MAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDE
Sbjct: 541 MAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDE 600
Query: 601 SEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMER 660
SEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMER
Sbjct: 601 SEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMER 660
Query: 661 IMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFET 720
IMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFET
Sbjct: 661 IMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFET 720
Query: 721 ATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDE 780
ATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDE
Sbjct: 721 ATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDE 780
Query: 781 EMDVGTDEEEETAKESTAEKDEL 803
EMDVGTDEEEETAKESTAEKDEL
Sbjct: 781 EMDVGTDEEEETAKESTAEKDEL 803
>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
Length = 724
Score = 657 bits (1696), Expect = 0.0
Identities = 353/737 (47%), Positives = 495/737 (67%), Gaps = 34/737 (4%)
Query: 65 QIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDEN 124
++ E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISNASDALDKIR SLTD +
Sbjct: 4 EVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPS 63
Query: 125 ALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQED 184
L +EL + I + ++ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA +
Sbjct: 64 KLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQA 119
Query: 185 GQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSN-EFSVIADPRGNTLGR 243
G S +IGQFGVGFYSA+LVA+KV+V +KHN+D Q+ WES + F+V AD G +GR
Sbjct: 120 GADIS-MIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRAD-HGEPIGR 177
Query: 244 GTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKT---ETVEEPMEEEEAAK 300
GT + L LKE+ ++YLE +K +VKK+SQFI +PI ++ K E ++ EEE+ K
Sbjct: 178 GTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEISDDEAEEEKGEK 237
Query: 301 EEKEESDDE------AAVEEEEE---EKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVE 351
EE+++ D+E +EE++ +KK KTKK+++ D E +N KPIW R ++
Sbjct: 238 EEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDIT 297
Query: 352 EDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKL 411
++EY FYKS + + +D +A HF+ EG++ F+++LF+P AP LF+ KK + IKL
Sbjct: 298 QEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFEN--KKKKNNIKL 355
Query: 412 YVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDM 471
YVRRVFI D +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK +V+K L++
Sbjct: 356 YVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLEL 415
Query: 472 IKKIADDKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVER 530
++A+DK N F++ F N+KLG+ ED +NR RL++LLR+ +S ++TSL +YV R
Sbjct: 416 FSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSR 475
Query: 531 MKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQN 590
MKE Q IY++ G S+++ +S FVER+ K+G+EV+Y+TEP+DEYC+Q L EFDGK +
Sbjct: 476 MKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVS 535
Query: 591 VAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVAS 650
V KEG++ E E+ K+ E + +FE L MK+ L K+EK +S RL SPC +V S
Sbjct: 536 VTKEGLELPEDEEEKKKMEESKAKFENLCKLMKE-ILDKKVEKVTISNRLVSSPCCIVTS 594
Query: 651 QYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTV 710
YGW+ NMERIMKAQA +D ST Y KK EINP HP++ + ++ + D++DK V
Sbjct: 595 TYGWTANMERIMKAQAL---RDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAV 651
Query: 711 LDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDT 770
DL V+LFETA L SG+ L D + + +RI RM++L L ID D E EEP D
Sbjct: 652 KDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDED----EVAAEEPNAAVPDE 707
Query: 771 TEDTEQDED----EEMD 783
E DED EE+D
Sbjct: 708 IPPLEGDEDASRMEEVD 724
Score = 32.0 bits (71), Expect = 2.3
Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Query: 752 DAKVEEEPEEEPEETAEDTTEDTEQD--EDEEMDVGTDEEEET--AKESTAEKDEL 803
D + EEE E+ EE +D + +D DEE D G D++++T KE +++EL
Sbjct: 227 DDEAEEEKGEKEEEDKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKEKYIDQEEL 282
>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
sapiens]
Length = 732
Score = 639 bits (1648), Expect = 0.0
Identities = 345/729 (47%), Positives = 479/729 (65%), Gaps = 27/729 (3%)
Query: 71 EKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNE 130
E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR SLTD + L +
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
Query: 131 ELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSE 190
EL + + +K+ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G S
Sbjct: 75 ELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGADIS- 129
Query: 191 LIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLV 250
+IGQFGVGFYSA+LVA+KV V +KHN+D Q+ WES + + G +GRGT + L
Sbjct: 130 MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILH 189
Query: 251 LKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKT--------ETVEEPMEEEEAAKEE 302
LKE+ ++YLE IK +VKK+SQFI +PI ++ K E E+ +EEE KEE
Sbjct: 190 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEE 249
Query: 303 KEESD----DEAAVEEEEEEK---KPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEY 355
KE D ++ +EEEE+K K K KK+++ D E +N KPIW R ++ +EY
Sbjct: 250 KESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEY 309
Query: 356 KAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRR 415
FYKS + + +D +A HF+ EG++ F+++LFVP AP LF+ KK + IKLYVRR
Sbjct: 310 GEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFEN--RKKKNNIKLYVRR 367
Query: 416 VFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKI 475
VFI D+ +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK LV+K L++ ++
Sbjct: 368 VFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEL 427
Query: 476 ADDKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEK 534
A+DK N F+++F NIKLG+ ED NR +L++LLR+ +S ++ SL Y RMKE
Sbjct: 428 AEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKEN 487
Query: 535 QDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKE 594
Q IY++ G ++ + +S FVERL K G EVIY+ EP+DEYC+Q L EF+GK +V KE
Sbjct: 488 QKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKE 547
Query: 595 GVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGW 654
G++ E E+ K+ +E + +FE L MKD L+ K+EK VVS RL SPC +V S YGW
Sbjct: 548 GLELPEDEEEKKKQEEKKTKFENLCKIMKD-ILEKKVEKVVVSNRLVTSPCCIVTSTYGW 606
Query: 655 SGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLA 714
+ NMERIMKAQA +D ST Y + KK EINP H +I + ++ + D++DK+V DL
Sbjct: 607 TANMERIMKAQAL---RDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLV 663
Query: 715 VVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDT 774
++L+ETA L SG+ L D + + +RI RM++L L ID D ++ E D
Sbjct: 664 ILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDD 723
Query: 775 EQDEDEEMD 783
+ EE+D
Sbjct: 724 DTSRMEEVD 732
Score = 35.4 bits (80), Expect = 0.21
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 733 KAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDED--EEMDVGTDEEE 790
K + I + L + + D +V ++ EE E+ E+ ++ ++ ED E DVG+DEEE
Sbjct: 208 KKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEE 267
Query: 791 ETAKESTAEKDEL 803
E +K ++
Sbjct: 268 EKKDGDKKKKKKI 280
Score = 34.7 bits (78), Expect = 0.36
Identities = 17/54 (31%), Positives = 30/54 (55%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
+ + K EE+ +EE E + ED DE+EE G ++++ KE +++EL
Sbjct: 237 EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 290
>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
sapiens]
Length = 854
Score = 639 bits (1648), Expect = 0.0
Identities = 345/729 (47%), Positives = 479/729 (65%), Gaps = 27/729 (3%)
Query: 71 EKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNE 130
E+ E FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR SLTD + L +
Sbjct: 137 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 196
Query: 131 ELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSE 190
EL + + +K+ L + DTG+GMT+ +L+ NLGTIAKSGT F+ EA + G S
Sbjct: 197 ELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFM----EALQAGADIS- 251
Query: 191 LIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLV 250
+IGQFGVGFYSA+LVA+KV V +KHN+D Q+ WES + + G +GRGT + L
Sbjct: 252 MIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILH 311
Query: 251 LKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKT--------ETVEEPMEEEEAAKEE 302
LKE+ ++YLE IK +VKK+SQFI +PI ++ K E E+ +EEE KEE
Sbjct: 312 LKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEE 371
Query: 303 KEESD----DEAAVEEEEEEK---KPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEY 355
KE D ++ +EEEE+K K K KK+++ D E +N KPIW R ++ +EY
Sbjct: 372 KESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEY 431
Query: 356 KAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRR 415
FYKS + + +D +A HF+ EG++ F+++LFVP AP LF+ KK + IKLYVRR
Sbjct: 432 GEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFEN--RKKKNNIKLYVRR 489
Query: 416 VFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKI 475
VFI D+ +++P+YLNF++GVVDS+DLPLN+SRE LQQ K+LKVIRK LV+K L++ ++
Sbjct: 490 VFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEL 549
Query: 476 ADDKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEK 534
A+DK N F+++F NIKLG+ ED NR +L++LLR+ +S ++ SL Y RMKE
Sbjct: 550 AEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKEN 609
Query: 535 QDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKE 594
Q IY++ G ++ + +S FVERL K G EVIY+ EP+DEYC+Q L EF+GK +V KE
Sbjct: 610 QKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKE 669
Query: 595 GVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGW 654
G++ E E+ K+ +E + +FE L MKD L+ K+EK VVS RL SPC +V S YGW
Sbjct: 670 GLELPEDEEEKKKQEEKKTKFENLCKIMKD-ILEKKVEKVVVSNRLVTSPCCIVTSTYGW 728
Query: 655 SGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLA 714
+ NMERIMKAQA +D ST Y + KK EINP H +I + ++ + D++DK+V DL
Sbjct: 729 TANMERIMKAQAL---RDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLV 785
Query: 715 VVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDT 774
++L+ETA L SG+ L D + + +RI RM++L L ID D ++ E D
Sbjct: 786 ILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDD 845
Query: 775 EQDEDEEMD 783
+ EE+D
Sbjct: 846 DTSRMEEVD 854
Score = 35.4 bits (80), Expect = 0.21
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 2/73 (2%)
Query: 733 KAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDED--EEMDVGTDEEE 790
K + I + L + + D +V ++ EE E+ E+ ++ ++ ED E DVG+DEEE
Sbjct: 330 KKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEE 389
Query: 791 ETAKESTAEKDEL 803
E +K ++
Sbjct: 390 EKKDGDKKKKKKI 402
Score = 34.7 bits (78), Expect = 0.36
Identities = 17/54 (31%), Positives = 30/54 (55%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
+ + K EE+ +EE E + ED DE+EE G ++++ KE +++EL
Sbjct: 359 EKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEEL 412
>gi|155722983 TNF receptor-associated protein 1 [Homo sapiens]
Length = 704
Score = 325 bits (832), Expect = 1e-88
Identities = 224/697 (32%), Positives = 366/697 (52%), Gaps = 92/697 (13%)
Query: 64 SQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDE 123
S ++ + K FQAE +++ ++ SLY KE+F+RELISNASDAL+K+R ++D
Sbjct: 76 SSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDG 135
Query: 124 NALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQE 183
AL E+ + ++ + EK + + DTG+GMT+EELV NLGTIA+SG+ FL+ + Q
Sbjct: 136 QALP---EMEIHLQTNAEKGTITIQDTGIGMTQEELVSNLGTIARSGSKAFLDAL---QN 189
Query: 184 DGQSTSELIGQFGVGFYSAFLVADKVIVTSKHN--NDTQHIWESDSNEFSVIADPRGNTL 241
+++S++IGQFGVGFYSAF+VAD+V V S+ + W SD + IA+ G +
Sbjct: 190 QAEASSKIIGQFGVGFYSAFMVADRVEVYSRSAAPGSLGYQWLSDGSGVFEIAEASG--V 247
Query: 242 GRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKE 301
GT I + LK + ++ ++++V KYS F++FP+Y+ +
Sbjct: 248 RTGTKIIIHLKSDCKEFSSEARVRDVVTKYSNFVSFPLYLNGRR---------------- 291
Query: 302 EKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKS 361
MN ++ IW K+V E +++ FY+
Sbjct: 292 ----------------------------------MNTLQAIWMMDPKDVREWQHEEFYRY 317
Query: 362 FSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFD---EYGSKKSDYIKLYVRRVFI 418
++ D P +H+ + + +SI +VP P +FD E GS + LY R+V I
Sbjct: 318 VAQAHDKPRYTLHYKTDAPLNIRSIFYVPDMKP-SMFDVSRELGSS----VALYSRKVLI 372
Query: 419 TDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQ----HKLLKVIRKKLVRKTLDMIKK 474
D++PK+L F++GVVDS+D+PLN+SRE LQ+ KL V++++L++ +D KK
Sbjct: 373 QTKATDILPKWLRFIRGVVDSEDIPLNLSRELLQESALIRKLRDVLQQRLIKFFIDQSKK 432
Query: 475 IADDKYNDTFWKEFGTNIKLGVI--EDHSNRTRLAKLLRFQSSHHPT-DITSLDQYVERM 531
A +KY F++++G ++ G++ + + +AKLLR++SS P+ +TSL +Y RM
Sbjct: 433 DA-EKY-AKFFEDYGLFMREGIVTATEQEVKEDIAKLLRYESSALPSGQLTSLSEYASRM 490
Query: 532 KEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNV 591
+ IY++ +R AE SP+ E + KK EV++ E DE + L EFD K+ +V
Sbjct: 491 RAGTRNIYYLCAPNRHLAEHSPYYEAMKKKDTEVLFCFEQFDELTLLHLREFDKKKLISV 550
Query: 592 AKEGVKFDESEKTKESREAV-----EKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCA 646
+ V E+ E R EKE E L+ WM++ L ++ V+ RL P
Sbjct: 551 ETDIVVDHYKEEKFEDRSPAAECLSEKETEELMAWMRN-VLGSRVTNVKVTLRLDTHPAM 609
Query: 647 LVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDED 706
+ + G + + R+ + Q + + T EINPRH LI+ L +++ E
Sbjct: 610 VTVLEMGAARHFLRMQQLAKTQEER------AQLLQPTLEINPRHALIK-KLNQLRASEP 662
Query: 707 DKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERML 743
L L ++E A + +G L+ D +A R+ +L
Sbjct: 663 GLAQL-LVDQIYENAMIAAG-LVDDPRAMVGRLNELL 697
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Query: 719 ETATLRSGYLLPDT--KAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQ 776
E T RS L P + A + + + + + D + EEE EEE E+ E+ E+ E+
Sbjct: 226 EVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEE 285
Query: 777 DEDEEMDVGTDEEEETAKESTAEKD 801
+E+EE + +EEEE +E A D
Sbjct: 286 EEEEEEEEEEEEEEEEEEEEEAAPD 310
Score = 43.9 bits (102), Expect = 6e-04
Identities = 20/47 (42%), Positives = 31/47 (65%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
EEE EEE EE E+ ++ E++E+EE + +EEEE +E E++E
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 43.9 bits (102), Expect = 6e-04
Identities = 20/47 (42%), Positives = 31/47 (65%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
EE+ EEE EE E+ E+ E++E+EE + +EEEE +E E++E
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 43.9 bits (102), Expect = 6e-04
Identities = 20/47 (42%), Positives = 31/47 (65%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
E+E EEE EE E+ E+ E++E+EE + +EEEE +E E++E
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 43.1 bits (100), Expect = 0.001
Identities = 20/52 (38%), Positives = 33/52 (63%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKD 801
+ + + EEE EEE EE E+ E+ E++E+EE + +EEEE A + ++D
Sbjct: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Score = 40.0 bits (92), Expect = 0.009
Identities = 19/48 (39%), Positives = 32/48 (66%)
Query: 281 VWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
+ S + E EE EEEE ++E+EE ++E EEEEEE++ + ++ E+
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301
Score = 40.0 bits (92), Expect = 0.009
Identities = 21/56 (37%), Positives = 34/56 (60%)
Query: 284 SKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDI 339
S E EE EEEE +E++EE ++E EEEEEE++ + ++ E+ + E D+
Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311
Score = 38.5 bits (88), Expect = 0.025
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 3/85 (3%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMN---DIKPIW 343
E EE EEEE +EE+EE ++E EEEEEE++ + + ++ + + P
Sbjct: 269 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328
Query: 344 QRPSKEVEEDEYKAFYKSFSKESDD 368
+ P + EY + S + D
Sbjct: 329 RGPESPSPKPEYSVIVEVRSDDDKD 353
Score = 37.7 bits (86), Expect = 0.043
Identities = 19/54 (35%), Positives = 31/54 (57%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
+ + + EEE EEE EE E+ E+ E++E+EE +E+T+ S + EL
Sbjct: 275 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328
Score = 36.6 bits (83), Expect = 0.095
Identities = 17/46 (36%), Positives = 31/46 (67%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
SSK + + EE+E +EE+EE +++ EEEEEE++ + ++ E+
Sbjct: 248 SSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEE 293
Score = 35.0 bits (79), Expect = 0.28
Identities = 17/51 (33%), Positives = 31/51 (60%)
Query: 752 DAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
DA EE +++ + E+ E+ E++E+EE + +EEEE +E E++E
Sbjct: 242 DAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEE 292
Score = 30.4 bits (67), Expect = 6.8
Identities = 15/64 (23%), Positives = 34/64 (53%)
Query: 739 IERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTA 798
+E S ++ P + + EE ++ + E+ +++E+EE + ++EEE +E
Sbjct: 225 VEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEE 284
Query: 799 EKDE 802
E++E
Sbjct: 285 EEEE 288
Score = 30.4 bits (67), Expect = 6.8
Identities = 21/65 (32%), Positives = 29/65 (44%), Gaps = 26/65 (40%)
Query: 290 EEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKE 349
EE EEEE +EE+EE ++E EEEEEE++ +E
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE--------------------------EEE 291
Query: 350 VEEDE 354
EE+E
Sbjct: 292 EEEEE 296
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 45.4 bits (106), Expect = 2e-04
Identities = 165/829 (19%), Positives = 323/829 (38%), Gaps = 110/829 (13%)
Query: 31 VEEDLGKSREGSRTDDEVVQR--EEEAIQLDGLNASQIR-----ELREKSEKFAFQAEVN 83
++ DL S E ++ Q + E + LD S EL+EK ++ A +
Sbjct: 606 IKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQM 665
Query: 84 RMMKLIINSLYKNKEIFLRELISNASDALDKI-RLISLTDENA---LSGNEELTVKIKCD 139
+ S + K+ +L A ++I +L SL D L N EL KI D
Sbjct: 666 ENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKIT-D 724
Query: 140 KEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQS----TSELIGQF 195
+K L + + REE++ L + KS SE E Q+ + TSE F
Sbjct: 725 LQKELNKEVEENEAL-REEVI--LLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLF 781
Query: 196 GVGFYSAFLVADKVIVTSKHNND---TQHIWESDSNEFSVIADPRGNTLGRGTTITLVLK 252
+ V + K +D TQ ++S EF + +VL+
Sbjct: 782 SEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLH---MDFEQKYKMVLE 838
Query: 253 EEASDYLELDTIKNLVKKYSQFI-------NFPIYVWSSKTETVEEPMEEEEAAKEEKEE 305
E E+ + +K+ + ++ KT V+E + E E KE+ E
Sbjct: 839 ENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLEN 898
Query: 306 SDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKE 365
D + ++ E EK T+K+++T + ++K + Q E+D+ K +S E
Sbjct: 899 RD--STLQTVEREKTLITEKLQQT------LEEVKTLTQ------EKDDLKQLQESLQIE 944
Query: 366 SDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDM 425
D + IH T + + L + + + + KS + R + + ++ +
Sbjct: 945 RDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGET 1004
Query: 426 MPKYLNFVKGVVDSDDLPLNVSRETL-----------QQHKLLKVIRKKLVRKTLDMIKK 474
++ + G+ DL + +TL QQ K+ +I++K + M++
Sbjct: 1005 KDEFQQKMVGIDKKQDLEAK-NTQTLTADVKDNEIIEQQRKIFSLIQEK--NELQQMLES 1061
Query: 475 IADDKYNDTFWKEFGTNIKLGVIEDHSNR------TRLAKLLRFQSSHHPTDITSLDQYV 528
+ +K + + NI++ + R + +++ + +H L +
Sbjct: 1062 VIAEK--EQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTC 1119
Query: 529 ERMKEKQDKIYFMAGSSRKEAESSPFVE----RLLKKGYEVIYLTEPVDEYCIQALPEFD 584
+R+ E ++K+ + +++ + V+ + KK E+ L + + L +
Sbjct: 1120 DRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKEL-TLEHME 1178
Query: 585 GKRFQNVAKEGVKFDESEK-------TKESREAVEKEFEPLLNWMKD---KALKDKIEKA 634
+R + K ++E + KE +++ E E + L ++++ L+ K E
Sbjct: 1179 TERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELK 1238
Query: 635 VVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDIST-NYYASQKKTFEINPRHPL 693
+ L E ++ + ++ + +T + I+T + S K E P
Sbjct: 1239 IAHIHLKEH-----------QETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHE 1287
Query: 694 IRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDA 753
+++L +KE + + ++ +L E +T + L RIE M RL LN
Sbjct: 1288 EQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLA-------RIE-MERLRLN----E 1335
Query: 754 KVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
K +E EE T E D + E ++V D+ +E +E+ A+ E
Sbjct: 1336 KFQESQEEIKSLTKE---RDNLKTIKEALEVKHDQLKEHIRETLAKIQE 1381
Score = 41.6 bits (96), Expect = 0.003
Identities = 160/796 (20%), Positives = 298/796 (37%), Gaps = 143/796 (17%)
Query: 61 LNASQIRELREK--SEKFAFQAEVNRMMKLIINSLYK--NKEIFLRELISNASD----AL 112
L+ + +RE+ E SE F ++ + ++ N K N+E EL S +D L
Sbjct: 453 LSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRADYDNLVL 512
Query: 113 DKIRL--------ISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLG 164
D +L + L ++N L E L K K D+E L+H + LVK+
Sbjct: 513 DYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEIS-----NLKNLVKHAE 567
Query: 165 TIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWE 224
+ +E +K+ +E +L + I + K N +
Sbjct: 568 VYNQDLENELSSKVELLREKEDQIKKL---------------QEYIDSQKLENIKMDL-- 610
Query: 225 SDSNEFSVIADPR--GNTLGRGTTITLVLKEEA----SDYLEL-DTIKNLVKKYSQFINF 277
S I DP+ TL T+ L K E+ S+ LEL + +K L Y Q N
Sbjct: 611 --SYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMEN- 667
Query: 278 PIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMN 337
I ++ S+ E ++ + E KE + ++ + + K PK + + EL
Sbjct: 668 DIQLYQSQLEAKKKMQVDLE--KELQSAFNEITKLTSLIDGKVPK-----DLLCNLELEG 720
Query: 338 DIKPIWQRPSKEVEEDE--------------YKAFYKSFSKESDDPMAYIH-FTAEGEVT 382
I + + +KEVEE+E + + KE D +H T+E +
Sbjct: 721 KITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL 780
Query: 383 FKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNF---VKGVVDS 439
F ++ S +GL +E G K D +F + +++F K V++
Sbjct: 781 FSEVVH-KESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEE 839
Query: 440 DDLP----LNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLG 495
++ +N+S+E + L ++ +L KT ++ +K +
Sbjct: 840 NERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTRE------------------ 881
Query: 496 VIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFV 555
+++ N ++Q E+++ + + + E E +
Sbjct: 882 -VQERLN--------------------EMEQLKEQLENRDSTLQTV------EREKTLIT 914
Query: 556 ERLLKKGYEVIYLTEPVDEY-CIQALPEFDGKRFQNVAKEGV--KFDESEKTKESREAVE 612
E+L + EV LT+ D+ +Q + + + ++ + V D E+ + + E++
Sbjct: 915 EKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESL- 973
Query: 613 KEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKD 672
K+ + +N +K K ++ + + E+ G + K T
Sbjct: 974 KQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADV 1033
Query: 673 ISTNYYASQKKTFEINPRHPLIRDMLRR-IKEDEDDKTVL--DLAVVLFETATLRSGYLL 729
Q+K F + ++ ML I E E KT L ++ + + LR LL
Sbjct: 1034 KDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELR---LL 1090
Query: 730 PD---------TKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTE-QDED 779
D + I++ LS D A+VEE+ +E+ ++ E + Q+E
Sbjct: 1091 GDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM 1150
Query: 780 EEMDVGTDEEEETAKE 795
EM +E E E
Sbjct: 1151 SEMQKKINEIENLKNE 1166
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/55 (45%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Query: 746 SLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEK 800
SL+ D D + EEE EEE EE E+ ED E++E+EE +EEEE + EK
Sbjct: 356 SLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEE----EEEEEEPQQRGQGEK 406
Score = 42.7 bits (99), Expect = 0.001
Identities = 20/38 (52%), Positives = 28/38 (73%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTK 324
E EE EEEE A+EE+EE ++E EEEEEE++P+ +
Sbjct: 364 EEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQR 401
Score = 38.1 bits (87), Expect = 0.033
Identities = 19/34 (55%), Positives = 23/34 (67%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKK 320
E EE EEEE EE+EE D+E EEEEEE++
Sbjct: 363 EEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEE 396
Score = 37.4 bits (85), Expect = 0.056
Identities = 19/43 (44%), Positives = 28/43 (65%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKT 329
E E EEEEA +EE+E+ ++E EEEEEE+ + + EK+
Sbjct: 365 EEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKS 407
Score = 37.0 bits (84), Expect = 0.073
Identities = 15/43 (34%), Positives = 28/43 (65%)
Query: 753 AKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKE 795
A + ++ +EE EE E+ E+ E++E+E+ + +EEEE +E
Sbjct: 355 ASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 37.0 bits (84), Expect = 0.073
Identities = 16/38 (42%), Positives = 28/38 (73%)
Query: 290 EEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVE 327
+E EEEE +EE+EE+++E +EEEEE++ + ++ E
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 34.7 bits (78), Expect = 0.36
Identities = 16/37 (43%), Positives = 22/37 (59%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEET 792
EEE EEE EE E+ E+ E++E+E G E+ T
Sbjct: 373 EEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSAT 409
Score = 33.5 bits (75), Expect = 0.80
Identities = 14/35 (40%), Positives = 26/35 (74%)
Query: 294 EEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
+E+E +EE EE ++EA EEEE+E++ + ++ E+
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEE 394
Score = 33.1 bits (74), Expect = 1.1
Identities = 16/48 (33%), Positives = 31/48 (64%)
Query: 281 VWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
V +S ++ +E EEE +EE+ E ++E EEEEEE++ + ++ ++
Sbjct: 353 VLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQ 400
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/70 (37%), Positives = 43/70 (61%), Gaps = 5/70 (7%)
Query: 735 YGDR-IERMLRLSLNIDPDAKVEEEPEE-EPEETAEDTTEDTEQDEDEEMDVGTDEEEET 792
+GD ++++L++ I+P+ EEE EE E EE E+ E+ E+DE+E DEE+E
Sbjct: 1854 FGDEDVKQILKM---IEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEE 1910
Query: 793 AKESTAEKDE 802
+ + EK+E
Sbjct: 1911 EEAAEGEKEE 1920
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/46 (41%), Positives = 28/46 (60%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKE 795
D + + EEE EEE EE E+T ++ E +E EE + E+EE +E
Sbjct: 1879 DEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEE 1924
Score = 38.5 bits (88), Expect = 0.025
Identities = 18/40 (45%), Positives = 28/40 (70%)
Query: 281 VWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKK 320
V++ + E +E E EE +EEKEE ++E A E+E+EEK+
Sbjct: 1870 VFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKE 1909
Score = 35.4 bits (80), Expect = 0.21
Identities = 18/44 (40%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Query: 286 TETVEEPMEEEEAAKEEKEES--DDEAAVEEEEEEKKPKTKKVE 327
TE EE EEEE +E++EE D+E +E+E+E+K + + E
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAE 1915
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 294 EEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
EEEE +EE+ E +DE EE+EEE + + EK
Sbjct: 1874 EEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEK 1908
Score = 32.0 bits (71), Expect = 2.3
Identities = 15/33 (45%), Positives = 22/33 (66%)
Query: 293 MEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKK 325
M E E EE+EE D+E EEE+EE+K + ++
Sbjct: 1865 MIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEE 1897
Score = 31.6 bits (70), Expect = 3.1
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 739 IERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQD-EDEEMDVGTDEEEETAKEST 797
+ +L + + D D K + E T E+ ED E++ E+E+ + ++EEETA+E
Sbjct: 1845 VSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKE 1904
Query: 798 AEKDE 802
E+ E
Sbjct: 1905 DEEKE 1909
Score = 30.8 bits (68), Expect = 5.2
Identities = 15/42 (35%), Positives = 25/42 (59%)
Query: 293 MEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWE 334
+E E +EE+EE ++E EE+EEEK+ ++ + D E
Sbjct: 1866 IEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEE 1907
Score = 30.4 bits (67), Expect = 6.8
Identities = 13/38 (34%), Positives = 25/38 (65%)
Query: 291 EPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
E EEE ++E+EE ++E E+EE+E++ +K ++
Sbjct: 1869 EVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDE 1906
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/70 (37%), Positives = 43/70 (61%), Gaps = 5/70 (7%)
Query: 735 YGDR-IERMLRLSLNIDPDAKVEEEPEE-EPEETAEDTTEDTEQDEDEEMDVGTDEEEET 792
+GD ++++L++ I+P+ EEE EE E EE E+ E+ E+DE+E DEE+E
Sbjct: 1854 FGDEDVKQILKM---IEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEE 1910
Query: 793 AKESTAEKDE 802
+ + EK+E
Sbjct: 1911 EEAAEGEKEE 1920
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/46 (41%), Positives = 28/46 (60%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKE 795
D + + EEE EEE EE E+T ++ E +E EE + E+EE +E
Sbjct: 1879 DEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEE 1924
Score = 38.5 bits (88), Expect = 0.025
Identities = 18/40 (45%), Positives = 28/40 (70%)
Query: 281 VWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKK 320
V++ + E +E E EE +EEKEE ++E A E+E+EEK+
Sbjct: 1870 VFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKE 1909
Score = 35.4 bits (80), Expect = 0.21
Identities = 18/44 (40%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Query: 286 TETVEEPMEEEEAAKEEKEES--DDEAAVEEEEEEKKPKTKKVE 327
TE EE EEEE +E++EE D+E +E+E+E+K + + E
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAE 1915
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/35 (45%), Positives = 22/35 (62%)
Query: 294 EEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
EEEE +EE+ E +DE EE+EEE + + EK
Sbjct: 1874 EEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEK 1908
Score = 32.0 bits (71), Expect = 2.3
Identities = 15/33 (45%), Positives = 22/33 (66%)
Query: 293 MEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKK 325
M E E EE+EE D+E EEE+EE+K + ++
Sbjct: 1865 MIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEE 1897
Score = 31.6 bits (70), Expect = 3.1
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 739 IERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQD-EDEEMDVGTDEEEETAKEST 797
+ +L + + D D K + E T E+ ED E++ E+E+ + ++EEETA+E
Sbjct: 1845 VSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKE 1904
Query: 798 AEKDE 802
E+ E
Sbjct: 1905 DEEKE 1909
Score = 30.8 bits (68), Expect = 5.2
Identities = 15/42 (35%), Positives = 25/42 (59%)
Query: 293 MEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWE 334
+E E +EE+EE ++E EE+EEEK+ ++ + D E
Sbjct: 1866 IEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEE 1907
Score = 30.4 bits (67), Expect = 6.8
Identities = 13/38 (34%), Positives = 25/38 (65%)
Query: 291 EPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
E EEE ++E+EE ++E E+EE+E++ +K ++
Sbjct: 1869 EVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDE 1906
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 44.3 bits (103), Expect = 5e-04
Identities = 22/58 (37%), Positives = 35/58 (60%)
Query: 746 SLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
SL+ + + + EEE E E EE E+ E E++E EE V +EEE+ K+ +K+E+
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEV 2299
Score = 43.5 bits (101), Expect = 8e-04
Identities = 25/65 (38%), Positives = 34/65 (52%)
Query: 290 EEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKE 349
EE EEEE KEE+E + + EEEE++KK K KK E+ E+ + + I E
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETE 2319
Query: 350 VEEDE 354
DE
Sbjct: 2320 SLSDE 2324
Score = 40.0 bits (92), Expect = 0.009
Identities = 19/48 (39%), Positives = 32/48 (66%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWE 334
E EE + EEE ++E+EE +++ +EEEE+KK K +K ++ V + E
Sbjct: 2256 EREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKE 2303
Score = 38.9 bits (89), Expect = 0.019
Identities = 21/68 (30%), Positives = 38/68 (55%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRP 346
E EE EEE +EE+EE +E EE++ EK+ + KK +K E + + + +++
Sbjct: 2250 EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK 2309
Query: 347 SKEVEEDE 354
+ + E+E
Sbjct: 2310 EEIMSEEE 2317
Score = 37.7 bits (86), Expect = 0.043
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Query: 290 EEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKE 349
+E + EE + E+EE +E V EEEEE+K + + EK V + E K ++ +E
Sbjct: 2240 QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV-EKEEEEKKKKKKEKKKEE 2298
Query: 350 VEEDE 354
V+E E
Sbjct: 2299 VQEKE 2303
Score = 37.4 bits (85), Expect = 0.056
Identities = 20/46 (43%), Positives = 28/46 (60%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
S +E EE EEEE +EE E ++E EEE EEK+ + ++ EK
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Score = 31.2 bits (69), Expect = 4.0
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 285 KTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQ 344
+ E+ E EE E+ +E E+ E+ EEEEE++ + ++ E+ V + E + +
Sbjct: 2219 EVESEEHFSEEMESLLDELEKQ--ESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 345 RPSKEVEEDEYKAFYKSFSKE 365
E EE+E K K KE
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKE 2297
Score = 30.4 bits (67), Expect = 6.8
Identities = 16/42 (38%), Positives = 23/42 (54%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
E EE M EEE EE ++E+ EEE +++ + K EK
Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEK 2348
Score = 30.0 bits (66), Expect = 8.9
Identities = 15/40 (37%), Positives = 22/40 (55%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKE 795
EE EE+ E +E+ TE +E+EE +EE + KE
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 44.3 bits (103), Expect = 5e-04
Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 41/232 (17%)
Query: 584 DGKRFQNVAKEGVKFDESEKTKE------SREAVEKEFEPLLNWMKDKALKDKIEKAVVS 637
+G R + + E K EK K+ ++++E + E +L +K++A K + E
Sbjct: 136 EGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE-MLRTVKEEAEKPEREAKEQH 194
Query: 638 QRLTESPCALVASQYGWSGNMERIMKAQAY-QTGKDISTNYYASQKKTFEINPRHPLIRD 696
Q+L E A +Q E+ + A A+ + D+ ++ +T HP +
Sbjct: 195 QKLWEEQLAAAKAQ------QEQELAADAFKELDDDMDGTVSVTELQT------HPEL-- 240
Query: 697 MLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNID------ 750
D D L A E L SG D ++ DR+ +R +
Sbjct: 241 -------DTDGDGALSEA----EAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDL 289
Query: 751 --PDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEK 800
P A EP+EE TE+ E++E+EE + +EEEE E E+
Sbjct: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQ 341
Score = 33.5 bits (75), Expect = 0.80
Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 3/45 (6%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVE 327
SS TE EE EEEE EE+EE +D E + E+ KP + E
Sbjct: 309 SSPTEEEEEEEEEEEEEAEEEEEEEDS---EVQGEQPKPASPAEE 350
Score = 33.1 bits (74), Expect = 1.1
Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 6/45 (13%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEE------EEEEKKP 321
S E EE EEEE A+EE+EE D E E+ EE+K P
Sbjct: 310 SPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMP 354
Score = 31.2 bits (69), Expect = 4.0
Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
Query: 286 TETVEE--PMEEEEAAKEEKEESDDEAAVEEEEEEK 319
TE EE P+ +EE+EE ++E EEEEEE+
Sbjct: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
Length = 1812
Score = 44.3 bits (103), Expect = 5e-04
Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 8/103 (7%)
Query: 703 EDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEE 762
+DEDD L ++ E A R Y P + DR + + +VEEE +EE
Sbjct: 193 DDEDDPVPLPVSGDKEEDAPHREDYFEPISP---DR--NSVPQEGQYSDEGEVEEEQQEE 247
Query: 763 PEETAEDTTEDTEQDEDEEMDVGTD---EEEETAKESTAEKDE 802
EE +D + E+DEDE+ D EEEE +E E+DE
Sbjct: 248 GEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDE 290
Score = 34.7 bits (78), Expect = 0.36
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
Query: 294 EEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEED 353
E EE +EE EE +D+ VEEEE+E + + V+ + + + + +E EE
Sbjct: 239 EVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVD------SIPEEEEEDEEEEGEEDEEG 292
Query: 354 EYKAFYKSFSKESD 367
E Y+ S + D
Sbjct: 293 EGDDGYEQISSDED 306
Score = 33.1 bits (74), Expect = 1.1
Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEE 790
D D + EE+ +E+ T + E+ E+DE+EE G ++EE
Sbjct: 254 DVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEE---GEEDEE 291
>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
Length = 1147
Score = 44.3 bits (103), Expect = 5e-04
Identities = 35/103 (33%), Positives = 49/103 (47%), Gaps = 8/103 (7%)
Query: 703 EDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEE 762
+DEDD L ++ E A R Y P + DR + + +VEEE +EE
Sbjct: 193 DDEDDPVPLPVSGDKEEDAPHREDYFEPISP---DR--NSVPQEGQYSDEGEVEEEQQEE 247
Query: 763 PEETAEDTTEDTEQDEDEEMDVGTD---EEEETAKESTAEKDE 802
EE +D + E+DEDE+ D EEEE +E E+DE
Sbjct: 248 GEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDE 290
Score = 34.7 bits (78), Expect = 0.36
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 6/74 (8%)
Query: 294 EEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEED 353
E EE +EE EE +D+ VEEEE+E + + V+ + + + + +E EE
Sbjct: 239 EVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVD------SIPEEEEEDEEEEGEEDEEG 292
Query: 354 EYKAFYKSFSKESD 367
E Y+ S + D
Sbjct: 293 EGDDGYEQISSDED 306
Score = 33.1 bits (74), Expect = 1.1
Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 3/41 (7%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEE 790
D D + EE+ +E+ T + E+ E+DE+EE G ++EE
Sbjct: 254 DVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEE---GEEDEE 291
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 43.9 bits (102), Expect = 6e-04
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Query: 744 RLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVG--TDEEEETAKESTAEKD 801
R + + D + +EE EEE EE E+ T+ E+++ E+M G DEEE+ +E+ A KD
Sbjct: 432 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKD 491
Score = 37.0 bits (84), Expect = 0.073
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 20/96 (20%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPI 342
+S+ ET +E EE + +EE+EE ++E A + EEEE D E M +
Sbjct: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEE-------------DLEQMQE---- 472
Query: 343 WQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAE 378
Q +E +E+E A K K PM+ + + E
Sbjct: 473 GQEDDEEEDEEEEAAAGKDGDK---SPMSSLQISNE 505
Score = 35.0 bits (79), Expect = 0.28
Identities = 16/52 (30%), Positives = 29/52 (55%)
Query: 751 PDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
P A E +E+ EE+ E+ E+ E++E+E D +E+ E +E + +E
Sbjct: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE 479
Score = 32.0 bits (71), Expect = 2.3
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 22 DDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEK 75
++E D EEDL + +EG D+E + EE A DG + S + L+ +EK
Sbjct: 454 EEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG-DKSPMSSLQISNEK 506
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 43.9 bits (102), Expect = 6e-04
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Query: 744 RLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVG--TDEEEETAKESTAEKD 801
R + + D + +EE EEE EE E+ T+ E+++ E+M G DEEE+ +E+ A KD
Sbjct: 432 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKD 491
Score = 37.0 bits (84), Expect = 0.073
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 20/96 (20%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPI 342
+S+ ET +E EE + +EE+EE ++E A + EEEE D E M +
Sbjct: 430 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEE-------------DLEQMQE---- 472
Query: 343 WQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAE 378
Q +E +E+E A K K PM+ + + E
Sbjct: 473 GQEDDEEEDEEEEAAAGKDGDK---SPMSSLQISNE 505
Score = 35.0 bits (79), Expect = 0.28
Identities = 16/52 (30%), Positives = 29/52 (55%)
Query: 751 PDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
P A E +E+ EE+ E+ E+ E++E+E D +E+ E +E + +E
Sbjct: 428 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE 479
Score = 32.0 bits (71), Expect = 2.3
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 22 DDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEK 75
++E D EEDL + +EG D+E + EE A DG + S + L+ +EK
Sbjct: 454 EEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG-DKSPMSSLQISNEK 506
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 43.9 bits (102), Expect = 6e-04
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 2/60 (3%)
Query: 744 RLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVG--TDEEEETAKESTAEKD 801
R + + D + +EE EEE EE E+ T+ E+++ E+M G DEEE+ +E+ A KD
Sbjct: 444 RAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKD 503
Score = 37.0 bits (84), Expect = 0.073
Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 20/96 (20%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPI 342
+S+ ET +E EE + +EE+EE ++E A + EEEE D E M +
Sbjct: 442 ASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEE-------------DLEQMQE---- 484
Query: 343 WQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAE 378
Q +E +E+E A K K PM+ + + E
Sbjct: 485 GQEDDEEEDEEEEAAAGKDGDK---SPMSSLQISNE 517
Score = 35.0 bits (79), Expect = 0.28
Identities = 16/52 (30%), Positives = 29/52 (55%)
Query: 751 PDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
P A E +E+ EE+ E+ E+ E++E+E D +E+ E +E + +E
Sbjct: 440 PSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE 491
Score = 32.0 bits (71), Expect = 2.3
Identities = 19/54 (35%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 22 DDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEK 75
++E D EEDL + +EG D+E + EE A DG + S + L+ +EK
Sbjct: 466 EEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDG-DKSPMSSLQISNEK 518
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 43.9 bits (102), Expect = 6e-04
Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRP 346
E E+ E E+ ++EK + +E E+E+ EKK T++ EK WD E M + + + +R
Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKK--TQEQEKKTWDQEKMREEESMRERE 719
Query: 347 SKEVEEDEYKAFYKSFSKESDDPM 370
K EE+E + +E ++ M
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKM 743
Score = 40.0 bits (92), Expect = 0.009
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 290 EEPMEEEEAAKEEKEES--DDEAAVEEEEEEKKPKTKKVEKTVWDW-ELMNDIKPIWQRP 346
+E M E+E E+EE D E + ++EE + KT++ EK WD E M + + + +R
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRERE 595
Query: 347 SKEVEEDEYKAFYKSFSKESDDPM 370
K EE+E + +E ++ M
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKM 619
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 6/76 (7%)
Query: 285 KTETVEEPMEEEEAAKE-EKEESDDEAAVEEEEE---EKKPKTKKVEKTVWDWE--LMND 338
KT EE M EEE +E EK+ ++E + E+EE E++ K ++ E+ +W+ E +
Sbjct: 577 KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
Query: 339 IKPIWQRPSKEVEEDE 354
+ +W++ K E++E
Sbjct: 637 EEKMWEQEEKMWEQEE 652
Score = 37.7 bits (86), Expect = 0.043
Identities = 19/69 (27%), Positives = 42/69 (60%), Gaps = 4/69 (5%)
Query: 290 EEPMEEEEAAKEEKEES--DDEAAVEEEEEE--KKPKTKKVEKTVWDWELMNDIKPIWQR 345
EE M+E+E +E+EE + E + E+EE+ ++ + + ++ +W+ E M + + IW++
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQ 792
Query: 346 PSKEVEEDE 354
K +++E
Sbjct: 793 EEKMRDQEE 801
Score = 37.4 bits (85), Expect = 0.056
Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 13/79 (16%)
Query: 285 KTETVEEPMEEEEAAKE-EKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWE--------L 335
KT EE M+EEE +E EK+ ++E + E+EE K +K E+ +W+ E L
Sbjct: 438 KTRDQEEKMQEEERIREREKKMREEEETMREQEE----KMQKQEENMWEQEEKEWQQQRL 493
Query: 336 MNDIKPIWQRPSKEVEEDE 354
+ +W++ + +E++
Sbjct: 494 PEQKEKLWEQEKMQEQEEK 512
Score = 36.6 bits (83), Expect = 0.095
Identities = 20/70 (28%), Positives = 42/70 (60%), Gaps = 4/70 (5%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEE--EEKKPKTKKVEKTVWDWE--LMNDIKPI 342
E VE+ EE++ ++EK+ D E ++EEE E++ K ++ E+T+ + E + + +
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 343 WQRPSKEVEE 352
W++ KE ++
Sbjct: 481 WEQEEKEWQQ 490
Score = 35.0 bits (79), Expect = 0.28
Identities = 21/73 (28%), Positives = 42/73 (57%), Gaps = 9/73 (12%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEE---EKKPKTKKVEKTVWDWELMNDIKPIW 343
E +E E+E+ +E+KE + E ++E+EE E++ K ++ E+ +W E + +W
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE-----ERLW 379
Query: 344 QRPSKEVEEDEYK 356
++ K++ E E K
Sbjct: 380 EQ-EKQMREQEQK 391
Score = 34.3 bits (77), Expect = 0.47
Identities = 20/71 (28%), Positives = 39/71 (54%), Gaps = 8/71 (11%)
Query: 285 KTETVEEPMEEEEAAKEEKEESDDEAAVEEEEE---EKKPKTKKVEKTVWDWELMNDIKP 341
KT E+ EEE + EK+ ++E + E+EE E++ K ++ E+ +W+ E +
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE-----EK 756
Query: 342 IWQRPSKEVEE 352
+W++ K E+
Sbjct: 757 MWEQEEKMWEQ 767
Score = 32.7 bits (73), Expect = 1.4
Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 10/68 (14%)
Query: 290 EEPMEEEEAAKEEKEE--SDDEAAVEEEEE---EKKPKTKKVEKTVWDWELMNDIKPIWQ 344
E+ M EEE E+EE + E ++E+EE E++ K ++ E+ +W+ E + +W+
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE-----EKMWE 649
Query: 345 RPSKEVEE 352
+ K E+
Sbjct: 650 QEEKMWEQ 657
Score = 32.3 bits (72), Expect = 1.8
Identities = 16/70 (22%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 285 KTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQ 344
KT+ E+ ++E +EE+ + E + EEEE + + +K+++ + ++ + +W+
Sbjct: 695 KTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ--EEKMQEQEEEMWE 752
Query: 345 RPSKEVEEDE 354
+ K E++E
Sbjct: 753 QEEKMWEQEE 762
Score = 30.8 bits (68), Expect = 5.2
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 8/89 (8%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEE--EKKPKTKKVEKTVWDWE------LMND 338
E E+ ++EE +EK+ E E+E++ E++ K + E+ +WD E
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 339 IKPIWQRPSKEVEEDEYKAFYKSFSKESD 367
K W + K EE+ + K +E +
Sbjct: 575 EKKTWDQEEKMREEERMREREKKMREEEE 603
Score = 30.4 bits (67), Expect = 6.8
Identities = 23/96 (23%), Positives = 49/96 (51%), Gaps = 13/96 (13%)
Query: 285 KTETVEEPMEEEEAAKEEKEES--DDEAAVEEEEEE--KKPKTKKVEKTVWDWELMND-- 338
K + EE M E+E +E+EE + E + E+EE+ ++ + + ++ +W+ E M +
Sbjct: 618 KMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 677
Query: 339 -----IKPIW--QRPSKEVEEDEYKAFYKSFSKESD 367
+ IW ++ K+ +E E K + + +E +
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE 713
Score = 30.0 bits (66), Expect = 8.9
Identities = 25/74 (33%), Positives = 35/74 (47%), Gaps = 4/74 (5%)
Query: 285 KTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVE----KTVWDWELMNDIK 340
K EE M E++ EKEE E E+ EK + KK++ KT E M + +
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450
Query: 341 PIWQRPSKEVEEDE 354
I +R K EE+E
Sbjct: 451 RIREREKKMREEEE 464
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 43.9 bits (102), Expect = 6e-04
Identities = 22/54 (40%), Positives = 33/54 (61%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
+ + + EEE EEE EE E+ E+ E+DE+E + +EEEE +E E+ EL
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
Score = 43.5 bits (101), Expect = 8e-04
Identities = 25/64 (39%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 740 ERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTED-TEQDEDEEMDVGTDEEEETAKESTA 798
E + +++N + + EEE EEE EE E+ ED E++EDEE +EEEE E
Sbjct: 876 EDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935
Query: 799 EKDE 802
E++E
Sbjct: 936 EEEE 939
Score = 40.8 bits (94), Expect = 0.005
Identities = 27/76 (35%), Positives = 43/76 (56%), Gaps = 2/76 (2%)
Query: 279 IYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMND 338
I + SS E EE EEEE +EE+EE D E EEE+EE+ + ++ E+ ++ E +
Sbjct: 881 ININSSDEEEEEEEEEEEEEEEEEEEEEDFEE--EEEDEEEYFEEEEEEEEEFEEEFEEE 938
Query: 339 IKPIWQRPSKEVEEDE 354
+ + +E EE+E
Sbjct: 939 EGELEEEEEEEDEEEE 954
Score = 39.3 bits (90), Expect = 0.015
Identities = 22/59 (37%), Positives = 33/59 (55%), Gaps = 6/59 (10%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTED------TEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+ + + EEE EEE EE E+ ED E++E+EE + +EEE +E E+DE
Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951
Score = 37.0 bits (84), Expect = 0.073
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 4/70 (5%)
Query: 287 ETVEEPMEEEEAAKE--EKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQ 344
E EE EEEE +E E+EE D+E EEEEEE++ ++ E+ + EL + + +
Sbjct: 894 EEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE--EGELEEEEEEEDE 951
Query: 345 RPSKEVEEDE 354
+E+EE E
Sbjct: 952 EEEEELEEVE 961
Score = 36.2 bits (82), Expect = 0.12
Identities = 20/54 (37%), Positives = 31/54 (57%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
+ D + EEE EEE E E+ E+ E++ +EE +EEEE +E E +E+
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV 960
Score = 34.7 bits (78), Expect = 0.36
Identities = 21/55 (38%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
Query: 282 WSSKTETVEEPMEEEEAAKEEKEE--SDDEAAVEEEEEEKKPKTKKVEKTVWDWE 334
+ + E EE EEEE +EE EE ++E +EEEEEE+ + ++ + V D E
Sbjct: 910 FEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLE 964
Score = 33.9 bits (76), Expect = 0.62
Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 1/67 (1%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPI-WQR 345
E EE E+EE EE+EE ++E E EEEE + + ++ E+ + E + +++ + +
Sbjct: 908 EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGT 967
Query: 346 PSKEVEE 352
EVEE
Sbjct: 968 AGGEVEE 974
Score = 32.7 bits (73), Expect = 1.4
Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 748 NIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
+ + + + EEE EE EE E+ E+ E++E E++ +EE+E +E E ++L
Sbjct: 909 DFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG-ELEEEEEEEDEEEEEELEEVEDL 963
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 43.5 bits (101), Expect = 8e-04
Identities = 56/229 (24%), Positives = 97/229 (42%), Gaps = 42/229 (18%)
Query: 584 DGKRFQNVAKEGVKFDESEKTKE------SREAVEKEFEPLLNWMKDKALKDKIEKAVVS 637
+G R + + E K EK K+ ++++E + E +L +K++A K + E
Sbjct: 136 EGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVE-MLRTVKEEAEKPEREAKEQH 194
Query: 638 QRLTESPCALVASQYGWSGNMERIMKAQAY-QTGKDISTNYYASQKKTFEINPRHPLIRD 696
Q+L E A +Q E+ + A A+ + D+ ++ +T HP +
Sbjct: 195 QKLWEEQLAAAKAQ------QEQELAADAFKELDDDMDGTVSVTELQT------HPEL-- 240
Query: 697 MLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNID------ 750
D D L A E L SG D ++ DR+ +R +
Sbjct: 241 -------DTDGDGALSEA----EAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDL 289
Query: 751 --PDAKVEEEP-EEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKES 796
P A EP EE+P + T E+ E++E+EE + +EEEE ++E+
Sbjct: 290 PAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEA 338
Score = 33.1 bits (74), Expect = 1.1
Identities = 15/30 (50%), Positives = 19/30 (63%)
Query: 292 PMEEEEAAKEEKEESDDEAAVEEEEEEKKP 321
P EEEE +EE+EE +E EE+ EE P
Sbjct: 311 PTEEEEEEEEEEEEEAEEEEEEEDSEEAPP 340
Score = 31.6 bits (70), Expect = 3.1
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 9/48 (18%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAA---------VEEEEEEKKP 321
S E EE EEEE A+EE+EE D E A EE+K P
Sbjct: 310 SPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMP 357
Score = 31.2 bits (69), Expect = 4.0
Identities = 16/36 (44%), Positives = 22/36 (61%), Gaps = 2/36 (5%)
Query: 286 TETVEE--PMEEEEAAKEEKEESDDEAAVEEEEEEK 319
TE EE P+ +EE+EE ++E EEEEEE+
Sbjct: 298 TEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEE 333
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 43.1 bits (100), Expect = 0.001
Identities = 20/44 (45%), Positives = 30/44 (68%)
Query: 760 EEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
EE+ EE ED E TE+ E+E+ D +E+E +KE+T EKD++
Sbjct: 511 EEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKI 554
Score = 33.9 bits (76), Expect = 0.62
Identities = 16/45 (35%), Positives = 27/45 (60%)
Query: 284 SKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
S+ E VEE E++ E+KEE + ++E+E+ K TK+ +K
Sbjct: 509 SQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDK 553
Score = 32.7 bits (73), Expect = 1.4
Identities = 26/109 (23%), Positives = 45/109 (41%), Gaps = 13/109 (11%)
Query: 221 HIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIY 280
++ + + N +++ G GR I +EE + E D + KK +
Sbjct: 479 YLTKKNENYKALVRRNYGKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEE------- 531
Query: 281 VWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKT 329
+ EE +E+E +KE +E D EE EE++ T + KT
Sbjct: 532 ------KKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQATPRGRKT 574
Score = 31.6 bits (70), Expect = 3.1
Identities = 16/49 (32%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDV-GTDEEEETAKEST 797
D K E++ EE+ +E +D ED++++ E+ + GT EE E +++T
Sbjct: 520 DKAEKTEKKEEEKKDEEEKDEKEDSKENTKEKDKIDGTAEETEEREQAT 568
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/54 (42%), Positives = 34/54 (62%), Gaps = 1/54 (1%)
Query: 749 IDPDAKVEEEPEEEPEETAE-DTTEDTEQDEDEEMDVGTDEEEETAKESTAEKD 801
I+ +A E E EEE E E +T E++E + DEE + ++EE E +ES AE+D
Sbjct: 91 IESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEED 144
Score = 40.0 bits (92), Expect = 0.009
Identities = 22/66 (33%), Positives = 39/66 (59%), Gaps = 6/66 (9%)
Query: 740 ERMLRLSLNIDPDAKVEEEPEEE---PEETAEDTTEDTEQDEDEEMDVGTDEEEETAKES 796
ER + + +++ E E EEE EE+ +++ E++E+D +EEM+ DE+E A+E
Sbjct: 88 EREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME---DEQESEAEED 144
Query: 797 TAEKDE 802
E+ E
Sbjct: 145 NQEEGE 150
Score = 35.8 bits (81), Expect = 0.16
Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 750 DPDAKVEEEPEEEP-EETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKD 801
+ +++ EEE E+E EE+ ED+ E+ E +++ E + EE E+ E E +
Sbjct: 108 EEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAE 160
Score = 33.5 bits (75), Expect = 0.80
Identities = 20/53 (37%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
D + +EE E + E+ E +E E+ E EE + ++EE ET +ES E DE
Sbjct: 72 DGEGAGKEEAEVKVEQEREIESEAGEESESEE-ESESEEESETEEESEDESDE 123
Score = 33.1 bits (74), Expect = 1.1
Identities = 14/43 (32%), Positives = 28/43 (65%)
Query: 285 KTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVE 327
++E EE EEE+ EE+ E+++E+ E +EE ++ +++E
Sbjct: 92 ESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEME 134
Score = 33.1 bits (74), Expect = 1.1
Identities = 15/45 (33%), Positives = 27/45 (60%)
Query: 284 SKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
S++E E EE E +E ++ESD+E+ + EEE + + + E+
Sbjct: 99 SESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEE 143
Score = 30.8 bits (68), Expect = 5.2
Identities = 14/44 (31%), Positives = 25/44 (56%)
Query: 284 SKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVE 327
S+TE E +EE+ ++ +EE +DE E EE+ ++ + E
Sbjct: 111 SETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQEEGESEAE 154
Score = 30.4 bits (67), Expect = 6.8
Identities = 24/99 (24%), Positives = 45/99 (45%), Gaps = 3/99 (3%)
Query: 282 WSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKP 341
W+ + EE E E++ E + EA E E EE +++ E++ + E ++
Sbjct: 67 WTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEE---ESESEEESETEEESEDESDE 123
Query: 342 IWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGE 380
+ S+E EDE ++ + ++E + A AE E
Sbjct: 124 ESEEDSEEEMEDEQESEAEEDNQEEGESEAEGETEAESE 162
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 43.1 bits (100), Expect = 0.001
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 12/113 (10%)
Query: 230 FSVIADPRGNTLGRGTTITLV---LKEEASDYLELDTIKNLVKKYS---------QFINF 277
FSV N L R ++L K + SDY E + N V++ Q
Sbjct: 664 FSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLA 723
Query: 278 PIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTV 330
P+ ++ E EE E+EE +E++EE ++E EEEEEE++ + ++ V
Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAV 776
Score = 43.1 bits (100), Expect = 0.001
Identities = 19/50 (38%), Positives = 32/50 (64%)
Query: 749 IDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTA 798
+ P A +EE EEE E+ E+ ++ E++E+EE + +EEEE +E+ A
Sbjct: 725 VQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAA 774
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/43 (46%), Positives = 28/43 (65%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTA 798
EEE EE+ EE ED E+ E++E+EE + +EEEE A + A
Sbjct: 735 EEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVA 777
Score = 39.3 bits (90), Expect = 0.015
Identities = 18/43 (41%), Positives = 28/43 (65%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTA 798
EEE EEE +E E+ E+ E++E+EE + +EEEE + + A
Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA 775
Score = 36.2 bits (82), Expect = 0.12
Identities = 15/45 (33%), Positives = 28/45 (62%)
Query: 758 EPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+P+ +E E+ ED E++E++E + +EEEE +E E++E
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770
Score = 30.0 bits (66), Expect = 8.9
Identities = 16/53 (30%), Positives = 27/53 (50%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+ + + +EE EEE EE E+ E+ E++E+ V E S++E E
Sbjct: 742 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSE 794
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/44 (50%), Positives = 29/44 (65%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAE 799
EEE EEE EE E E++ +EE DV +DEEEE +ES++E
Sbjct: 426 EEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSE 469
Score = 39.3 bits (90), Expect = 0.015
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Query: 735 YGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTD--EEEET 792
+G + SL + + + EEE EEE EE + E+ ++E+EE G + EEEE
Sbjct: 389 FGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEV 448
Query: 793 AKESTAEKDE 802
+E + DE
Sbjct: 449 EEEGDVDSDE 458
Score = 35.4 bits (80), Expect = 0.21
Identities = 19/36 (52%), Positives = 23/36 (63%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEE 318
S K+E EE EEEE +EE E ++E EEEEEE
Sbjct: 400 SLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE 435
Score = 32.0 bits (71), Expect = 2.3
Identities = 15/35 (42%), Positives = 23/35 (65%)
Query: 286 TETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKK 320
T +++ EEEE +EE+EE + E EEEE E++
Sbjct: 398 TTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
Score = 31.6 bits (70), Expect = 3.1
Identities = 16/33 (48%), Positives = 20/33 (60%)
Query: 286 TETVEEPMEEEEAAKEEKEESDDEAAVEEEEEE 318
T T E EE +EE+EE ++E EEEEEE
Sbjct: 396 TITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEE 428
Score = 31.2 bits (69), Expect = 4.0
Identities = 15/30 (50%), Positives = 20/30 (66%)
Query: 290 EEPMEEEEAAKEEKEESDDEAAVEEEEEEK 319
EE EEEE +EE+ E ++E EEEEE+
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEE 435
Score = 30.8 bits (68), Expect = 5.2
Identities = 18/46 (39%), Positives = 27/46 (58%), Gaps = 1/46 (2%)
Query: 287 ETVEEPMEEEEAAKEEK-EESDDEAAVEEEEEEKKPKTKKVEKTVW 331
E EE E EE +EE+ EE D + EEEEE+++ ++ +E W
Sbjct: 431 EEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDW 476
Score = 30.4 bits (67), Expect = 6.8
Identities = 14/27 (51%), Positives = 19/27 (70%)
Query: 294 EEEEAAKEEKEESDDEAAVEEEEEEKK 320
EEEE +EE+EE + E EE EEE++
Sbjct: 408 EEEEEEEEEEEEGEGEEEEEEGEEEEE 434
Score = 30.4 bits (67), Expect = 6.8
Identities = 17/42 (40%), Positives = 24/42 (57%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEK 328
E EE EEEE EE+EE +E E E E+ + ++VE+
Sbjct: 409 EEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE 450
Score = 30.0 bits (66), Expect = 8.9
Identities = 15/43 (34%), Positives = 24/43 (55%)
Query: 761 EEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
EE EE E+ E+ + E+EE + +EEE E E++E+
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEV 448
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/110 (29%), Positives = 56/110 (50%), Gaps = 13/110 (11%)
Query: 706 DDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRI-----------ERMLRLSLNIDPDAK 754
D+ VL L + ++ T+ +L+ + +AY + E+ ++ + + K
Sbjct: 309 DNFGVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQMKDKQDEEQRLK 368
Query: 755 VEEEPEE-EPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL 803
EEE ++ + EE AED +D ++DEDEE + +E+EE A KDEL
Sbjct: 369 EEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQA-KDEL 417
Score = 31.6 bits (70), Expect = 3.1
Identities = 16/43 (37%), Positives = 24/43 (55%)
Query: 285 KTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVE 327
K EE E++E +++ E+ +DE EE+EEE P K E
Sbjct: 374 KKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEEDVPGQAKDE 416
Score = 31.2 bits (69), Expect = 4.0
Identities = 17/56 (30%), Positives = 33/56 (58%)
Query: 298 AAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEED 353
A K+ K++ D+E ++EEEE+KK K ++ + D E ++ + + ++ EED
Sbjct: 353 AEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEEED 408
Score = 30.4 bits (67), Expect = 6.8
Identities = 13/34 (38%), Positives = 22/34 (64%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKK 320
E E+ +EE E+KE+ +D+ EE+EE+K+
Sbjct: 369 EEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKE 402
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/58 (43%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 748 NIDPDAKVEEEPEEEPEETAEDTTEDTEQDED---EEMDVGTDEEEETAKESTAEKDE 802
N + + + EE EE EE ED ED E DED EE + +EEEE +E E+DE
Sbjct: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 749 IDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTD-----EEEETAKESTAEKD 801
+D D + EEE EEE EE E+ E+ EQDE ++ + G D E ++ ES + D
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Score = 40.0 bits (92), Expect = 0.009
Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 748 NIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+++ D +VEE+ EE+ EE ED E+ E++E+EE + +EEEE ++ +K+E
Sbjct: 208 DVEEDEEVEEDAEED-EEVDEDGEEEEEEEEEEE-EEEEEEEEEYEQDERDQKEE 260
Score = 39.3 bits (90), Expect = 0.015
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 17/96 (17%)
Query: 284 SKTETVEEPMEEEEAAK---EEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIK 340
++ E VEE +EE+E + EE EE D++ EEEEEE++ + ++ E+ ++ +
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD------ 253
Query: 341 PIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFT 376
+R KE D Y + S+ SD + FT
Sbjct: 254 ---ERDQKEEGND-----YDTRSEASDSGSESVSFT 281
Score = 38.1 bits (87), Expect = 0.033
Identities = 17/61 (27%), Positives = 36/61 (59%)
Query: 731 DTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEE 790
+T+ + +E + ++ DA+ +EE +E+ EE E+ E+ E++E+EE + DE +
Sbjct: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
Query: 791 E 791
+
Sbjct: 257 Q 257
Score = 37.4 bits (85), Expect = 0.056
Identities = 17/53 (32%), Positives = 31/53 (58%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+ D +V+E+ EEE EE E+ E+ E++E+ E D +EE ++ +E +
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272
Score = 36.2 bits (82), Expect = 0.12
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWD 332
+ + E V+E EEEE +EE+EE ++E EEEE E+ + +K E +D
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEE---EEEEYEQDERDQKEEGNDYD 265
Score = 33.1 bits (74), Expect = 1.1
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 8/54 (14%)
Query: 757 EEPEEEPEETAEDTTEDTEQD--------EDEEMDVGTDEEEETAKESTAEKDE 802
+E E E ED E+D EDEE+D +EEEE +E E++E
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/58 (43%), Positives = 32/58 (55%), Gaps = 3/58 (5%)
Query: 748 NIDPDAKVEEEPEEEPEETAEDTTEDTEQDED---EEMDVGTDEEEETAKESTAEKDE 802
N + + + EE EE EE ED ED E DED EE + +EEEE +E E+DE
Sbjct: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 749 IDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTD-----EEEETAKESTAEKD 801
+D D + EEE EEE EE E+ E+ EQDE ++ + G D E ++ ES + D
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282
Score = 40.0 bits (92), Expect = 0.009
Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Query: 748 NIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+++ D +VEE+ EE+ EE ED E+ E++E+EE + +EEEE ++ +K+E
Sbjct: 208 DVEEDEEVEEDAEED-EEVDEDGEEEEEEEEEEE-EEEEEEEEEYEQDERDQKEE 260
Score = 39.3 bits (90), Expect = 0.015
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 17/96 (17%)
Query: 284 SKTETVEEPMEEEEAAK---EEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIK 340
++ E VEE +EE+E + EE EE D++ EEEEEE++ + ++ E+ ++ +
Sbjct: 200 NEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQD------ 253
Query: 341 PIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFT 376
+R KE D Y + S+ SD + FT
Sbjct: 254 ---ERDQKEEGND-----YDTRSEASDSGSESVSFT 281
Score = 38.1 bits (87), Expect = 0.033
Identities = 17/61 (27%), Positives = 36/61 (59%)
Query: 731 DTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEE 790
+T+ + +E + ++ DA+ +EE +E+ EE E+ E+ E++E+EE + DE +
Sbjct: 197 NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERD 256
Query: 791 E 791
+
Sbjct: 257 Q 257
Score = 37.4 bits (85), Expect = 0.056
Identities = 17/53 (32%), Positives = 31/53 (58%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+ D +V+E+ EEE EE E+ E+ E++E+ E D +EE ++ +E +
Sbjct: 220 EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272
Score = 36.2 bits (82), Expect = 0.12
Identities = 20/50 (40%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 283 SSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWD 332
+ + E V+E EEEE +EE+EE ++E EEEE E+ + +K E +D
Sbjct: 219 AEEDEEVDEDGEEEEEEEEEEEEEEEE---EEEEYEQDERDQKEEGNDYD 265
Score = 33.1 bits (74), Expect = 1.1
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 8/54 (14%)
Query: 757 EEPEEEPEETAEDTTEDTEQD--------EDEEMDVGTDEEEETAKESTAEKDE 802
+E E E ED E+D EDEE+D +EEEE +E E++E
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/77 (32%), Positives = 47/77 (61%), Gaps = 5/77 (6%)
Query: 252 KEEASDYLELDTIKNL---VKKYSQFINFPIYVWSSKTETVEEPME-EEEAAKEEKEESD 307
+E AS+ +EL+++++ + ++P+ V +TE EE E +EE +EE+EE +
Sbjct: 75 QESASEDIELESLEDFEHFLMSGESLFHYPL-VGEEETEREEEDEEIQEEGGEEEEEEEE 133
Query: 308 DEAAVEEEEEEKKPKTK 324
+E EEEEEE++ + +
Sbjct: 134 EEEEEEEEEEEEEEQPR 150
Score = 35.8 bits (81), Expect = 0.16
Identities = 17/36 (47%), Positives = 24/36 (66%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEE 791
E E EEE EE E+ E+ E++E+EE + +EEEE
Sbjct: 110 ETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEE 145
Score = 34.7 bits (78), Expect = 0.36
Identities = 18/54 (33%), Positives = 30/54 (55%)
Query: 740 ERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETA 793
E + L + + + EEE EE EE E+ E+ E++E+EE + +EE+ A
Sbjct: 98 ESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRA 151
Score = 32.3 bits (72), Expect = 1.8
Identities = 16/55 (29%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
Query: 750 DPDAKVEEE--PEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
+ D +++EE EEE EE E+ E+ E++E+E+ G ++ + E+D+
Sbjct: 115 EEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQ 169
Score = 32.0 bits (71), Expect = 2.3
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 755 VEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKE 795
V EE E EE E E E++E+EE + +EEEE +E
Sbjct: 106 VGEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEE 146
Score = 32.0 bits (71), Expect = 2.3
Identities = 14/35 (40%), Positives = 23/35 (65%)
Query: 768 EDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
E+ TE E+DE+ + + G +EEEE +E E++E
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEE 142
Score = 30.8 bits (68), Expect = 5.2
Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 5/45 (11%)
Query: 758 EPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDE 802
E E E EE E+ E+ ++E+EE +EEEE +E E++E
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEE-----EEEEEEEEEEEEEEEE 147
Score = 30.4 bits (67), Expect = 6.8
Identities = 16/43 (37%), Positives = 22/43 (51%)
Query: 756 EEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTA 798
EEE EEE EE E+ E+ EQ G + E+ + +E A
Sbjct: 128 EEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQA 170
Score = 30.0 bits (66), Expect = 8.9
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 760 EEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEK 800
EEE E ED E E+EE + +EEEE +E E+
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 2/55 (3%)
Query: 750 DPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETA--KESTAEKDE 802
D + VEE EEE EE A + ED +DEDE+ + ++ E A +E+ AE+DE
Sbjct: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE 57
Score = 35.0 bits (79), Expect = 0.28
Identities = 21/61 (34%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Query: 296 EEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEY 355
EE +E +EE +EAAVEEEE+ ++ + ++ E D E + + R ++ EE+E
Sbjct: 5 EEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEE--TRAEEDEEEEEA 62
Query: 356 K 356
K
Sbjct: 63 K 63
Score = 34.7 bits (78), Expect = 0.36
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 3/48 (6%)
Query: 752 DAKVEEEPE--EEPEETAEDTTEDTEQD-EDEEMDVGTDEEEETAKES 796
+A VEEE + E+ +E E ED E + E EE DEEEE AKE+
Sbjct: 18 EAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEA 65
Score = 32.0 bits (71), Expect = 2.3
Identities = 18/43 (41%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 756 EEEPEEEPEETAEDT--TEDTEQDEDEEMDVGTDEEEETAKES 796
E+E EE EE AE TE+T +EDEE + + E+ +ES
Sbjct: 31 EDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEES 73
Score = 30.8 bits (68), Expect = 5.2
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 9/52 (17%)
Query: 282 WSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEE---------EEKKPKTK 324
W + EE EE+ A+ E EE+ E EEEE EE KPK +
Sbjct: 27 WREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPR 78
Score = 30.4 bits (67), Expect = 6.8
Identities = 16/43 (37%), Positives = 23/43 (53%)
Query: 287 ETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKT 329
E EE +EE A +EE++ +DE EE EE + E+T
Sbjct: 9 EEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEET 51
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/50 (40%), Positives = 28/50 (56%)
Query: 752 DAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKD 801
D+ EEE ++E + ED ED E D+D+E D G +E E + E T D
Sbjct: 1947 DSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTGMGDEGEDSNEGTGSAD 1996
Score = 37.7 bits (86), Expect = 0.043
Identities = 84/395 (21%), Positives = 157/395 (39%), Gaps = 64/395 (16%)
Query: 285 KTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMN----DIK 340
KTET+ ME + +EEKE +E++ ++ + K +K+E + + N +
Sbjct: 1265 KTETMNVVMETNKMLREEKER------LEQDLQQMQAKVRKLELDILPLQEANAELSEKS 1318
Query: 341 PIWQRPSKEVEED--EYKAFYKSFSKESDDP--MAYIHFTAEGEVTFKSILFVPTSAPRG 396
+ Q K +EED +KA + + DP Y +E EV K I +
Sbjct: 1319 GMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRI--------QQ 1370
Query: 397 LFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKL 456
L +E G K++ + + + N ++ + + D + +ET+Q+
Sbjct: 1371 LTEEIGRLKAEIAR-----------SNASLTNNQNLIQSLKE-DLNKVRTEKETIQKDLD 1418
Query: 457 LKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSH 516
K+I + KT+ +KKI G K E + + ++ + S
Sbjct: 1419 AKIIDIQEKVKTITQVKKI-------------GRRYKTQYEELKAQQDKVMETSAQSSGD 1465
Query: 517 HPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYC 576
H S+ Q ++ +KE ++ A + K ES VE L K E + E
Sbjct: 1466 HQEQHVSV-QEMQELKETLNQ----AETKSKSLESQ--VENLQKTLSEKETEARNLQEQT 1518
Query: 577 IQALPEFDGKR----FQNVAKEGVKFDESEKTKESREAV--EKEFEPLLNWMKDKALKD- 629
+Q E R + +E ++ +EK +++R+A+ K L +KD+ K+
Sbjct: 1519 VQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTKEN 1578
Query: 630 ---KIEKAVVSQRLTESPCALVASQYGWSGNMERI 661
K + Q+ E + A + + G + R+
Sbjct: 1579 EELKQRNGALDQQKDELDVRITALKSQYEGRISRL 1613
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,772,459
Number of Sequences: 37866
Number of extensions: 1378983
Number of successful extensions: 30420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 360
Number of HSP's successfully gapped in prelim test: 308
Number of HSP's that attempted gapping in prelim test: 13360
Number of HSP's gapped (non-prelim): 10903
length of query: 803
length of database: 18,247,518
effective HSP length: 110
effective length of query: 693
effective length of database: 14,082,258
effective search space: 9759004794
effective search space used: 9759004794
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.