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Search of human proteins with 4507553
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507553 tropomodulin 1 [Homo sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507553 tropomodulin 1 [Homo sapiens] 707 0.0
gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens] 431 e-121
gi|156415984 tropomodulin 4 (muscle) [Homo sapiens] 420 e-118
gi|7657647 neuronal tropomodulin isoform a [Homo sapiens] 413 e-115
gi|218931148 neuronal tropomodulin isoform b [Homo sapiens] 345 4e-95
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens] 237 1e-62
gi|54607116 leiomodin 3 (fetal) [Homo sapiens] 160 2e-39
gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens] 156 3e-38
gi|5174617 nucleotide-binding oligomerization domain containing ... 52 6e-07
gi|118918429 NOD3 protein [Homo sapiens] 52 1e-06
gi|11545912 nucleotide-binding oligomerization domain containing... 51 2e-06
gi|229577123 t-complex-associated testis expressed 1 [Homo sapiens] 42 7e-04
gi|168986655 hypothetical protein LOC145497 [Homo sapiens] 40 0.003
gi|38176300 nestin [Homo sapiens] 37 0.036
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens] 35 0.10
gi|21361959 solute carrier family 35, member F5 [Homo sapiens] 35 0.14
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo... 35 0.14
gi|118498356 kinectin 1 isoform a [Homo sapiens] 34 0.23
gi|118498368 kinectin 1 isoform c [Homo sapiens] 34 0.23
gi|33620775 kinectin 1 isoform a [Homo sapiens] 34 0.23
gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens] 33 0.30
gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens] 33 0.30
gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens] 33 0.30
gi|23503285 leucine rich repeat containing 34 [Homo sapiens] 33 0.30
gi|18641360 collectin sub-family member 12 [Homo sapiens] 33 0.52
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 33 0.52
gi|118498362 kinectin 1 isoform b [Homo sapiens] 32 0.67
gi|156104908 myosin heavy chain 6 [Homo sapiens] 32 0.88
gi|63054866 leucine rich repeat containing 16A [Homo sapiens] 32 1.2
gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 32 1.2
>gi|4507553 tropomodulin 1 [Homo sapiens]
Length = 359
Score = 707 bits (1825), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG 60
MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG
Sbjct: 1 MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG 60
Query: 61 PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELEEAL 120
PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELEEAL
Sbjct: 61 PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELEEAL 120
Query: 121 ANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNS 180
ANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNS
Sbjct: 121 ANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNS 180
Query: 181 TDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPV 240
TDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPV
Sbjct: 181 TDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPV 240
Query: 241 AYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEM 300
AYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEM
Sbjct: 241 AYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEM 300
Query: 301 EIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV 359
EIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV
Sbjct: 301 EIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGV 359
>gi|7657649 tropomodulin 3 (ubiquitous) [Homo sapiens]
Length = 352
Score = 431 bits (1107), Expect = e-121
Identities = 215/345 (62%), Positives = 275/345 (79%), Gaps = 1/345 (0%)
Query: 1 MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG 60
+ +R++LEKY+DLDEDE+LG L+E EL+ LE LD+LDP+NALLPAG RQK+QT+K+ TG
Sbjct: 3 LPFRKDLEKYKDLDEDELLGNLSETELKQLETVLDDLDPENALLPAGFRQKNQTSKSTTG 62
Query: 61 PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLES-VTLEPELEEA 119
PF RE LL +LEK+A E KDRED VPYTGEK+GK+++PKQKP+ E V+L+PELEEA
Sbjct: 63 PFDREHLLSYLEKEALEHKDREDYVPYTGEKKGKIFIPKQKPVQTFTEEKVSLDPELEEA 122
Query: 120 LANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPN 179
L +ASD ELCD+AAILGMH L++N ++ + SS+ +++E ++V+K + PV DE PN
Sbjct: 123 LTSASDTELCDLAAILGMHNLITNTKFCNIMGSSNGVDQEHFSNVVKGEKILPVFDEPPN 182
Query: 180 STDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDP 239
T+VEE+L+R K ND L EVNLNNI+NIPIPTLK +A+AL+ N++VK FS+ TRSNDP
Sbjct: 183 PTNVEESLKRTKENDAHLVEVNLNNIKNIPIPTLKDFAKALETNTHVKCFSLAATRSNDP 242
Query: 240 VAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVE 299
VA A AEMLK NK LK+LNVESNFI+G GIL L++AL N +L E+KIDNQ Q LG VE
Sbjct: 243 VATAFAEMLKVNKTLKSLNVESNFITGVGILALIDALRDNETLAELKIDNQRQQLGTAVE 302
Query: 300 MEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRL 344
+E+ MLE+N +LKFGY FTQQGPR RA+NA+ NNDLVRKRR+
Sbjct: 303 LEMAKMLEENTNILKFGYQFTQQGPRTRAANAITKNNDLVRKRRV 347
>gi|156415984 tropomodulin 4 (muscle) [Homo sapiens]
Length = 345
Score = 420 bits (1080), Expect = e-118
Identities = 201/342 (58%), Positives = 277/342 (80%), Gaps = 1/342 (0%)
Query: 2 SYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGP 61
SY++ELEKYRD+DEDEIL L+ EEL L+ EL E+DP+N LLPAGLRQ+DQT K+PTGP
Sbjct: 3 SYQKELEKYRDIDEDEILRTLSPEELEQLDCELQEMDPENMLLPAGLRQRDQTKKSPTGP 62
Query: 62 FKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELEEALA 121
RE LL +LE+QA E K+R+DLVP+TGEK+GK ++ ++ + P E +TLEPELEEALA
Sbjct: 63 LDREALLQYLEQQALEVKERDDLVPFTGEKKGKPYIQPKREI-PAEEQITLEPELEEALA 121
Query: 122 NASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNST 181
+A+DAE+CDIAAIL M+TLMSN+QYY AL S I N EG++SV++P +YKPVPDE PN T
Sbjct: 122 HATDAEMCDIAAILDMYTLMSNKQYYDALCSGEICNTEGISSVVQPDKYKPVPDEPPNPT 181
Query: 182 DVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVA 241
++EE L+R+++ND +LEEVNLNNI++IPIP L EA+K N+YV+ FS+V TRS DP+A
Sbjct: 182 NIEEILKRVRSNDKELEEVNLNNIQDIPIPMLSELCEAMKANTYVRSFSLVATRSGDPIA 241
Query: 242 YALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEME 301
A+A+ML+EN+ L++LN+ESNFIS G++ +++A+ N +L E+++DNQ Q G+ VEME
Sbjct: 242 NAVADMLRENRSLQSLNIESNFISSTGLMAVLKAVRENATLTELRVDNQRQWPGDAVEME 301
Query: 302 IVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRR 343
+ ++LE+ ++++FGYHFTQQGPR RA+ AM NN+L R+++
Sbjct: 302 MATVLEQCPSIVRFGYHFTQQGPRARAAQAMTRNNELRRQQK 343
>gi|7657647 neuronal tropomodulin isoform a [Homo sapiens]
Length = 351
Score = 413 bits (1061), Expect = e-115
Identities = 206/345 (59%), Positives = 276/345 (80%), Gaps = 2/345 (0%)
Query: 1 MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG 60
+ +++ELEKY+++DEDE+LG L+EEEL+ LEN LD+LDP++A+LPAG RQKDQT KA TG
Sbjct: 3 LPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATG 62
Query: 61 PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLES-VTLEPELEEA 119
PF RE LL +LEK+A E KDRED VP+TGEK+G+V++PK+KP++ E VTL+PELEEA
Sbjct: 63 PFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEA 122
Query: 120 LANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPN 179
LA+ASD EL D+AA+LG+H L++N ++ + +++ K + +V+K + KPV +E PN
Sbjct: 123 LASASDTELYDLAAVLGVHNLLNNPKFDEETANNK-GGKGPVRNVVKGEKVKPVFEEPPN 181
Query: 180 STDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDP 239
T+VE +L+++K NDP L+EVNLNNI+NIPIPTL+ +A+AL+ N++VKKFS+ TRSNDP
Sbjct: 182 PTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDP 241
Query: 240 VAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVE 299
VA A A+MLK NK L +LN+ESNFI+G GIL LVEAL N +L E+KIDNQ Q LG VE
Sbjct: 242 VAIAFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVE 301
Query: 300 MEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRL 344
MEI MLE+N+ +LKFGY FT+QGPR R + A+ NNDLVRK+R+
Sbjct: 302 MEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRV 346
>gi|218931148 neuronal tropomodulin isoform b [Homo sapiens]
Length = 315
Score = 345 bits (885), Expect = 4e-95
Identities = 182/345 (52%), Positives = 245/345 (71%), Gaps = 38/345 (11%)
Query: 1 MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG 60
+ +++ELEKY+++DEDE+LG L+EEEL+ LEN LD+LDP++A+LPAG RQKDQT KA TG
Sbjct: 3 LPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATG 62
Query: 61 PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDP-VLESVTLEPELEEA 119
PF RE LL +LEK+A E KDRED VP+TGEK+G+V++PK+KP++ E VTL+PELEEA
Sbjct: 63 PFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEA 122
Query: 120 LANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPN 179
LA+ASD EL D+AA+LG+H L++N ++ + +++ K + +V+K + KPV +E PN
Sbjct: 123 LASASDTELYDLAAVLGVHNLLNNPKFDEETANNK-GGKGPVRNVVKGEKVKPVFEEPPN 181
Query: 180 STDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDP 239
T+VE +L+++K NDP L+EVNLNNI+
Sbjct: 182 PTNVEISLQQMKANDPSLQEVNLNNIK--------------------------------- 208
Query: 240 VAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVE 299
A A+MLK NK L +LN+ESNFI+G GIL LVEAL N +L E+KIDNQ Q LG VE
Sbjct: 209 ---AFADMLKVNKTLTSLNIESNFITGTGILALVEALKENDTLTEIKIDNQRQQLGTAVE 265
Query: 300 MEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRL 344
MEI MLE+N+ +LKFGY FT+QGPR R + A+ NNDLVRK+R+
Sbjct: 266 MEIAQMLEENSRILKFGYQFTKQGPRTRVAAAITKNNDLVRKKRV 310
>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
Length = 547
Score = 237 bits (604), Expect = 1e-62
Identities = 147/363 (40%), Positives = 212/363 (58%), Gaps = 25/363 (6%)
Query: 3 YRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPF 62
YRR L KY +DEDE+L +L+ EEL+ LE EL++++PD L P GLRQK T K PTG F
Sbjct: 6 YRRGLSKYESIDEDELLASLSAEELKELERELEDIEPDRNL-PVGLRQKSLTEKTPTGTF 64
Query: 63 KREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVL---------ESVTLE 113
RE L+ + EK++++ ++E L GE GKV K++ + ++ E V E
Sbjct: 65 SREALMAYWEKESQKLLEKERL----GEC-GKVAEDKEESEEELIFTESNSEVSEEVYTE 119
Query: 114 PELEEALANA----SDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNK--EGLN----S 163
E EE+ SD E I G++ ++ S I E +N S
Sbjct: 120 EEEEESQEEEEEEDSDEEERTIETAKGINGTVNYDSVNSDNSKPKIFKSQIENINLTNGS 179
Query: 164 VIKPTQYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKEN 223
+ T+ N T +E+ L++IK+NDP EVNLNNI NI TL +AEALK+N
Sbjct: 180 NGRNTESPAAIHPCGNPTVIEDALDKIKSNDPDTTEVNLNNIENITTQTLTRFAEALKDN 239
Query: 224 SYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLV 283
+ VK FS+ T ++D A A+AEMLK N+ + +NVESNFI+G GIL ++ AL +NT L
Sbjct: 240 TVVKTFSLANTHADDSAAMAIAEMLKVNEHITNVNVESNFITGKGILAIMRALQHNTVLT 299
Query: 284 EMKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRR 343
E++ NQ +G++VEMEIV +L++N TLL+ GYHF GPR+ ++ + N D R++R
Sbjct: 300 ELRFHNQRHIMGSQVEMEIVKLLKENTTLLRLGYHFELPGPRMSMTSILTRNMDKQRQKR 359
Query: 344 LAD 346
L +
Sbjct: 360 LQE 362
>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
Length = 560
Score = 160 bits (404), Expect = 2e-39
Identities = 74/165 (44%), Positives = 112/165 (67%)
Query: 179 NSTDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSND 238
N TD++ +L R++ NDP ++E+NLNNI NIP L + A+K+N ++K FS+ +++
Sbjct: 237 NQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADE 296
Query: 239 PVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKV 298
VA+ALA ML+EN+ + TLN+ESNFI+G GI+ ++ L +N +L E++ NQ LG+
Sbjct: 297 NVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHA 356
Query: 299 EMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRR 343
EMEI +L+ N TLLK GYHF GPR+ +N + N D R++R
Sbjct: 357 EMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKR 401
>gi|112380630 leiomodin 1 (smooth muscle) [Homo sapiens]
Length = 600
Score = 156 bits (394), Expect = 3e-38
Identities = 82/196 (41%), Positives = 121/196 (61%)
Query: 151 SSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNIRNIPI 210
S + K+ + KP++ +EE + +E LER+KNNDP++ EVN+NN I
Sbjct: 286 SKTKTPEKQTPSGPTKPSEGPAKVEEEAAPSIFDEPLERVKNNDPEMTEVNVNNSDCITN 345
Query: 211 PTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGIL 270
L + EAL+ N+ VK F++ TR++D VA+A+A MLK NK + +LN++SN I+G GIL
Sbjct: 346 EILVRFTEALEFNTVVKLFALANTRADDHVAFAIAIMLKANKTITSLNLDSNHITGKGIL 405
Query: 271 RLVEALPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASN 330
+ AL N +L E++ NQ G K EMEI +L++N TLLK GYHF GPR+ +N
Sbjct: 406 AIFRALLQNNTLTELRFHNQRHICGGKTEMEIAKLLKENTTLLKLGYHFELAGPRMTVTN 465
Query: 331 AMMNNNDLVRKRRLAD 346
+ N D R++RL +
Sbjct: 466 LLSRNMDKQRQKRLQE 481
Score = 68.6 bits (166), Expect = 8e-12
Identities = 36/80 (45%), Positives = 52/80 (65%), Gaps = 3/80 (3%)
Query: 3 YRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPF 62
YRR++ + D D D +L L+ EE+ LE ELD +DPD ++ P GLRQ++QT K TG +
Sbjct: 7 YRRQVSE--DPDIDSLLETLSPEEMEELEKELDVVDPDGSV-PVGLRQRNQTEKQSTGVY 63
Query: 63 KREELLDHLEKQAKEFKDRE 82
RE +L+ EK+ K+ RE
Sbjct: 64 NREAMLNFCEKETKKLMQRE 83
>gi|5174617 nucleotide-binding oligomerization domain containing 1
[Homo sapiens]
Length = 953
Score = 52.4 bits (124), Expect = 6e-07
Identities = 38/123 (30%), Positives = 63/123 (51%), Gaps = 7/123 (5%)
Query: 193 NDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENK 252
N P L ++L + I K+ A AL++N+ ++ + ND VA +LAEMLK N+
Sbjct: 838 NHPSLTTLSLAS-NGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQ 896
Query: 253 VLKTLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATL 312
LK L + N I+ G +L +AL NT + E+ ++ GN ++ E + E +
Sbjct: 897 TLKHLWLIQNQITAKGTAQLADALQSNTGITEICLN------GNLIKPEEAKVYEDEKRI 950
Query: 313 LKF 315
+ F
Sbjct: 951 ICF 953
>gi|118918429 NOD3 protein [Homo sapiens]
Length = 1065
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/97 (37%), Positives = 55/97 (56%), Gaps = 4/97 (4%)
Query: 217 AEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEAL 276
A+ALK+N +K+ D A ALAE LK N+ L++L+++SN IS AG+ L+ AL
Sbjct: 771 ADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGLESLDLQSNSISDAGVAALMGAL 830
Query: 277 PYNTSLVEMKI-DNQSQPLGNKVEMEIVSMLEKNATL 312
N +L+ + + +N P G + I L N+TL
Sbjct: 831 CTNQTLLSLSLRENSISPEGAQA---IAHALCANSTL 864
Score = 49.3 bits (116), Expect = 5e-06
Identities = 28/78 (35%), Positives = 41/78 (52%)
Query: 214 KAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLV 273
KA A+ALK N + S+ G D A ++AE L N+ L L+++ N I G R+
Sbjct: 712 KALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNRTLSMLHLQKNSIGPMGAQRMA 771
Query: 274 EALPYNTSLVEMKIDNQS 291
+AL N SL E+ + S
Sbjct: 772 DALKQNRSLKELMFSSNS 789
Score = 45.8 bits (107), Expect = 6e-05
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Query: 214 KAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLV 273
+A A AL NS +K + +D A A+A ++EN+ L +L+++ NFI L
Sbjct: 852 QAIAHALCANSTLKNLDLTANLLHDQGARAIAVAVRENRTLTSLHLQWNFIQAGAAQALG 911
Query: 274 EALPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATL 312
+AL N SL +D Q +G+ + L+ N L
Sbjct: 912 QALQLNRSLT--SLDLQENAIGDDGACAVARALKVNTAL 948
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/240 (23%), Positives = 99/240 (41%), Gaps = 13/240 (5%)
Query: 107 LESVTLEPELEEALANASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEG-LNSVI 165
L+ L +EEA+ + + A L A + L+ ++ S+ +G L S++
Sbjct: 574 LQHTELARSVEEAMESGALARLTGPAHRAALAYLLQVSDACAQEANLSLSLSQGVLQSLL 633
Query: 166 KPTQY--KPVPDEEPNSTDVEETLERI-KNNDPKLEEVNL--NNIRNIPIPTLKAYAEAL 220
Y K D V E L + D ++++++L N I N KA A +L
Sbjct: 634 PQLLYCRKLRLDTNQFQDPVMELLGSVLSGKDCRIQKISLAENQISN---KGAKALARSL 690
Query: 221 KENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNT 280
N + + G A ALA+ LK N+ L +L+++ N + G + EAL N
Sbjct: 691 LVNRSLTSLDLRGNSIGPQGAKALADALKINRTLTSLSLQGNTVRDDGARSMAEALASNR 750
Query: 281 SLVEMKIDNQSQPLGNKVEMEIVSMLEKNATL--LKFGYHFTQQGPRLRASNAMMNNNDL 338
+L + + Q +G + L++N +L L F + G + A+ N L
Sbjct: 751 TLSMLHL--QKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALAEALKVNQGL 808
Score = 40.8 bits (94), Expect = 0.002
Identities = 36/132 (27%), Positives = 52/132 (39%), Gaps = 9/132 (6%)
Query: 214 KAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLV 273
++ AEAL N + + A +A+ LK+N+ LK L SN I G L
Sbjct: 740 RSMAEALASNRTLSMLHLQKNSIGPMGAQRMADALKQNRSLKELMFSSNSIGDGGAKALA 799
Query: 274 EALPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGP-------RL 326
EAL N L +D QS + + ++ L N TLL P
Sbjct: 800 EALKVNQGL--ESLDLQSNSISDAGVAALMGALCTNQTLLSLSLRENSISPEGAQAIAHA 857
Query: 327 RASNAMMNNNDL 338
+N+ + N DL
Sbjct: 858 LCANSTLKNLDL 869
Score = 32.3 bits (72), Expect = 0.67
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 2/93 (2%)
Query: 218 EALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALP 277
EAL N ++ + G A ALA LK N L+ LN++ N + G + + AL
Sbjct: 968 EALAVNRTLEILDLRGNAIGVAGAKALANALKVNSSLRRLNLQENSLGMDGAICIATALS 1027
Query: 278 YNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNA 310
N L I+ Q +G+ I ++ NA
Sbjct: 1028 GNHRL--QHINLQGNHIGDSGARMISEAIKTNA 1058
>gi|11545912 nucleotide-binding oligomerization domain containing 2
[Homo sapiens]
Length = 1040
Score = 50.8 bits (120), Expect = 2e-06
Identities = 35/102 (34%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
Query: 214 KAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLV 273
+A AEAL ++ ++ S+VG A ALA ML +N +L+ L +E N + G+ L
Sbjct: 917 QALAEALGDHQSLRWLSLVGNNIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLA 976
Query: 274 EALPYNTSLVEMKIDNQS-QPLGNKVEMEIVSMLEKNATLLK 314
E L N+SL +K+ N LG + ++ LE+N T+L+
Sbjct: 977 EGLKKNSSLKILKLSNNCITYLGAEA---LLQALERNDTILE 1015
Score = 37.7 bits (86), Expect = 0.016
Identities = 28/96 (29%), Positives = 47/96 (48%), Gaps = 2/96 (2%)
Query: 217 AEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEAL 276
AE L+ N+ ++ G R D A ALAE L +++ L+ L++ N I G L L
Sbjct: 892 AEGLRGNTSLQFLGFWGNRVGDEGAQALAEALGDHQSLRWLSLVGNNIGSVGAQALALML 951
Query: 277 PYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATL 312
N L E+ ++ L ++ + L+KN++L
Sbjct: 952 AKNVMLEELCLEENH--LQDEGVCSLAEGLKKNSSL 985
Score = 36.6 bits (83), Expect = 0.036
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 207 NIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISG 266
NI +A A L +N +++ + D +LAE LK+N LK L + +N I+
Sbjct: 938 NIGSVGAQALALMLAKNVMLEELCLEENHLQDEGVCSLAEGLKKNSSLKILKLSNNCITY 997
Query: 267 AGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEMEIVSML 306
G L++AL N +++E+ + GN +E V L
Sbjct: 998 LGAEALLQALERNDTILEVWL------RGNTFSLEEVDKL 1031
Score = 32.3 bits (72), Expect = 0.67
Identities = 17/57 (29%), Positives = 32/57 (56%)
Query: 226 VKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSL 282
++K ++ + D A+++A++L + L + +N+I+ AG L E L NTSL
Sbjct: 845 LQKLALFNNKLTDGCAHSMAKLLACRQNFLALRLGNNYITAAGAQVLAEGLRGNTSL 901
>gi|229577123 t-complex-associated testis expressed 1 [Homo sapiens]
Length = 501
Score = 42.4 bits (98), Expect = 7e-04
Identities = 38/151 (25%), Positives = 65/151 (43%), Gaps = 5/151 (3%)
Query: 196 KLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLK 255
+L +NL N + P ++ A AL N+ + ++ D ALA L+ NK L
Sbjct: 335 RLRVLNLAN-NQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLT 393
Query: 256 TLNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLKF 315
TL++ N +S L + L NT+L + + +G +++ + N TLL+F
Sbjct: 394 TLHLGGNELSEPTATLLSQVLAINTTLTSINL--SCNHIGLDGGKQLLEGMSDNKTLLEF 451
Query: 316 GYHFTQ--QGPRLRASNAMMNNNDLVRKRRL 344
+ Q A+ N + R+R L
Sbjct: 452 DLRLSDVAQESEYLIGQALYANREAARQRAL 482
Score = 29.3 bits (64), Expect = 5.7
Identities = 16/69 (23%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 219 ALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPY 278
+L ++ +++ + D A A++L ++ L+ LN+ +N + G L AL +
Sbjct: 302 SLLDHPVLEELDLSQNLIGDRGARGAAKLLSHSR-LRVLNLANNQVRAPGAQSLAHALAH 360
Query: 279 NTSLVEMKI 287
NT+L+ + +
Sbjct: 361 NTNLISLNL 369
>gi|168986655 hypothetical protein LOC145497 [Homo sapiens]
Length = 488
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/146 (28%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Query: 167 PTQYKPVPDEEPNSTDVE-ETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSY 225
PT K P E + TD+E E E+ K E+ L + + + + + ++E+
Sbjct: 53 PTVEKVKPARENSETDLEIEDDEKFFTTGQK--ELYLEACKLMGVVPVSYFIRNMEESYV 110
Query: 226 VKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPYNTSLVEM 285
+G R +A AL N + L +E N I G+L LVE L N L EM
Sbjct: 111 NLNHHGLGPRGTKAIAIALVS----NMAVTKLELEDNCIMEEGVLSLVEMLQENYYLQEM 166
Query: 286 KIDNQSQPLGNKVEMEIVSMLEKNAT 311
I N LG + I E+N++
Sbjct: 167 NISNNH--LGLEGARIISDFFERNSS 190
Score = 34.7 bits (78), Expect = 0.14
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 2/96 (2%)
Query: 218 EALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALP 277
+AL N +KK + + +D L +ML N L +L++ N G + L L
Sbjct: 212 QALSTNYQIKKLDLSHNQFSDVGGEHLGQMLAINVGLTSLDLSWNNFHTRGAVALCNGLR 271
Query: 278 YNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLL 313
N +L K+D GN+V + + +L N L+
Sbjct: 272 GNVTLT--KLDLSMNGFGNEVALALGEVLRLNRCLV 305
Score = 33.1 bits (74), Expect = 0.40
Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 200 VNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNV 259
VNLN+ P T KA A AL N V K + + +L EML+EN L+ +N+
Sbjct: 110 VNLNHHGLGPRGT-KAIAIALVSNMAVTKLELEDNCIMEEGVLSLVEMLQENYYLQEMNI 168
Query: 260 ESNFISGAGILRLVEALPYNTSLV 283
+N + G + + N+S +
Sbjct: 169 SNNHLGLEGARIISDFFERNSSSI 192
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 36.6 bits (83), Expect = 0.036
Identities = 53/223 (23%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 2 SYRRELEKYRDLDEDEI--------------LGALTEEELRTLENELDE-LDPDNALLPA 46
S ++E+ + DL+ EI LG +E L+TLEN+ E L+ +N P
Sbjct: 518 SLQQEIWEEEDLNRKEIQDSQVPLEKETLKSLGEEIQESLKTLENQSHETLERENQECPR 577
Query: 47 GLRQKDQTTKAPTGPFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPV 106
L + +T K+ + +ELL +E K+ + TG++ + QK +
Sbjct: 578 SLEEDLETLKSLEK--ENKELLKDVEVVRPLEKEAVGQLKPTGKEDTQTLQSLQKENQEL 635
Query: 107 LESVTLEPELEEALANASDAELCDIAAILGMHTLMS-NQQYYQALSSSSIMNKEGLNSVI 165
++S LE LE L ++ + + + +L + ++ + L S + ++E L +
Sbjct: 636 MKS--LEGNLETFLFPGTENQELVSSLQENLESLTALEKENQEPLRSPEVGDEEALRPLT 693
Query: 166 KPTQYKPVPDEEPNSTDVEETLERIKNNDP--KLEEVNLNNIR 206
K Q +P+ E + + +LE+ +N +P LEE + + +R
Sbjct: 694 KENQ-EPLRSLEDENKEAFRSLEK-ENQEPLKTLEEEDQSIVR 734
>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
Length = 1378
Score = 35.0 bits (79), Expect = 0.10
Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)
Query: 219 ALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEALPY 278
ALK ++ +++ + G R D L L L L++ SN + G+ +L LP
Sbjct: 1065 ALKLHTALRELRLAGNRLGDKCVAELVAALGTMPSLALLDLSSNHLGPEGLRQLAMGLPG 1124
Query: 279 NTSLVEM-KIDNQSQPLGNKVEMEIVSML 306
+L + ++D PLG+ + S+L
Sbjct: 1125 QATLQSLEELDLSMNPLGDGCGQSLASLL 1153
>gi|21361959 solute carrier family 35, member F5 [Homo sapiens]
Length = 523
Score = 34.7 bits (78), Expect = 0.14
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 146 YYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLERIKNNDPKLEEVNLNNI 205
Y+ A ++ + MN + P ++ +P E+P ST+++ PK V +NI
Sbjct: 146 YFAACTTDTTMNSSLSEPLYVPVKFHDLPSEKPESTNID------TEKTPKKSRVRFSNI 199
Query: 206 RNI-PIPTLKAYAEALKENSYVKK 228
I +P+ A L SY K
Sbjct: 200 MEIRQLPSSHALEAKLSRMSYPVK 223
>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
sapiens]
Length = 1866
Score = 34.7 bits (78), Expect = 0.14
Identities = 37/151 (24%), Positives = 61/151 (40%), Gaps = 7/151 (4%)
Query: 197 LEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKT 256
LEE++L+N KA AL+ +K+ + N L L + L++
Sbjct: 1524 LEELDLSN-NQFDEEGTKALMRALEGKWMLKRLDLSHLLLNSSTLALLTHRLSQMTCLQS 1582
Query: 257 LNVESNFISGAGILRLVEALPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLKFG 316
L + N I G L EAL TSL E+ + + +G+ + ++L L K
Sbjct: 1583 LRLNRNSIGDVGCCHLSEALRAATSLEELDLSHNQ--IGDAGVQHLATILPGLPELRKID 1640
Query: 317 YHFTQQGPRLRASNAMMNNNDLVRKRRLADL 347
G + ++ + LV RRL +L
Sbjct: 1641 L----SGNSISSAGGVQLAESLVLCRRLEEL 1667
Score = 28.9 bits (63), Expect = 7.5
Identities = 17/77 (22%), Positives = 38/77 (49%)
Query: 214 KAYAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLV 273
+A L+E ++++ + G + D +AE + + + L++ N +S AG+ ++
Sbjct: 860 EALIALLQEGPHLEEVDLSGNQLEDEGCRLMAEAASQLHIARKLDLSDNGLSVAGVHCVL 919
Query: 274 EALPYNTSLVEMKIDNQ 290
A+ +L E+ I Q
Sbjct: 920 RAVSACWTLAELHISLQ 936
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 33.9 bits (76), Expect = 0.23
Identities = 68/335 (20%), Positives = 143/335 (42%), Gaps = 46/335 (13%)
Query: 15 EDEILGALTEEELR-----TLENELDELDPDNALLPAGLRQKDQTTKAPTGP-FKREELL 68
E ++ + E+ R +L+ ++ ++ N L A ++Q A T EEL
Sbjct: 547 EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELH 606
Query: 69 DHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELE--EALANASDA 126
+ ++ K+ K ED + +R ++ +++ D + L+ E++ +ALAN A
Sbjct: 607 KVIAEKDKQIKQTEDSL---ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAA 663
Query: 127 ELCDIAAILG----------------MHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQY 170
++ + H + + + ++ L+ + + L S ++ Q
Sbjct: 664 AAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN----KALKSEVQKLQ- 718
Query: 171 KPVPDEEPNSTDVEETLERIKNNDPKLEEV-NLNNIRNIPIPTLKAYAEALK--ENSYVK 227
+ E+PN VE+ + I+ D KL+ V L I + T + A++ +S K
Sbjct: 719 -TLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTK 777
Query: 228 KFSIVGTRSNDPVAYA-LAEMLK-----ENKVLKTLN--VESNFISGAGILRLVEALPYN 279
+ + + ND V++A L E LK ++ +K++ +E+ + A + V+ L
Sbjct: 778 EVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE 837
Query: 280 TSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLK 314
++ +I N L ++ I S +++ LLK
Sbjct: 838 IKALKEEIGNVQ--LEKAQQLSITSKVQELQNLLK 870
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 33.9 bits (76), Expect = 0.23
Identities = 68/335 (20%), Positives = 143/335 (42%), Gaps = 46/335 (13%)
Query: 15 EDEILGALTEEELR-----TLENELDELDPDNALLPAGLRQKDQTTKAPTGP-FKREELL 68
E ++ + E+ R +L+ ++ ++ N L A ++Q A T EEL
Sbjct: 547 EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELH 606
Query: 69 DHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELE--EALANASDA 126
+ ++ K+ K ED + +R ++ +++ D + L+ E++ +ALAN A
Sbjct: 607 KVIAEKDKQIKQTEDSL---ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAA 663
Query: 127 ELCDIAAILG----------------MHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQY 170
++ + H + + + ++ L+ + + L S ++ Q
Sbjct: 664 AAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN----KALKSEVQKLQ- 718
Query: 171 KPVPDEEPNSTDVEETLERIKNNDPKLEEV-NLNNIRNIPIPTLKAYAEALK--ENSYVK 227
+ E+PN VE+ + I+ D KL+ V L I + T + A++ +S K
Sbjct: 719 -TLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTK 777
Query: 228 KFSIVGTRSNDPVAYA-LAEMLK-----ENKVLKTLN--VESNFISGAGILRLVEALPYN 279
+ + + ND V++A L E LK ++ +K++ +E+ + A + V+ L
Sbjct: 778 EVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE 837
Query: 280 TSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLK 314
++ +I N L ++ I S +++ LLK
Sbjct: 838 IKALKEEIGNVQ--LEKAQQLSITSKVQELQNLLK 870
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 33.9 bits (76), Expect = 0.23
Identities = 68/335 (20%), Positives = 143/335 (42%), Gaps = 46/335 (13%)
Query: 15 EDEILGALTEEELR-----TLENELDELDPDNALLPAGLRQKDQTTKAPTGP-FKREELL 68
E ++ + E+ R +L+ ++ ++ N L A ++Q A T EEL
Sbjct: 547 EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELH 606
Query: 69 DHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELE--EALANASDA 126
+ ++ K+ K ED + +R ++ +++ D + L+ E++ +ALAN A
Sbjct: 607 KVIAEKDKQIKQTEDSL---ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAA 663
Query: 127 ELCDIAAILG----------------MHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQY 170
++ + H + + + ++ L+ + + L S ++ Q
Sbjct: 664 AAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN----KALKSEVQKLQ- 718
Query: 171 KPVPDEEPNSTDVEETLERIKNNDPKLEEV-NLNNIRNIPIPTLKAYAEALK--ENSYVK 227
+ E+PN VE+ + I+ D KL+ V L I + T + A++ +S K
Sbjct: 719 -TLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTK 777
Query: 228 KFSIVGTRSNDPVAYA-LAEMLK-----ENKVLKTLN--VESNFISGAGILRLVEALPYN 279
+ + + ND V++A L E LK ++ +K++ +E+ + A + V+ L
Sbjct: 778 EVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQE 837
Query: 280 TSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATLLK 314
++ +I N L ++ I S +++ LLK
Sbjct: 838 IKALKEEIGNVQ--LEKAQQLSITSKVQELQNLLK 870
>gi|229892308 shugoshin-like 2 isoform 2 [Homo sapiens]
Length = 1260
Score = 33.5 bits (75), Expect = 0.30
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 89 GEKRGKVWVPKQKPLDPVLESVTLEPELE-EALANASDAELCDIAA--ILGMHTLMSNQQ 145
G K+G + Q+ +P+ E++ + EL+ AL+ + CD +LG+ ++N
Sbjct: 640 GLKKGNFFFKTQEDKEPISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNM- 698
Query: 146 YYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLER----IKNNDPKLEEVN 201
Y + S +NK+ V + T+ + N +E T++ + D ++ N
Sbjct: 699 -YPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGN 757
Query: 202 LNNIRNIPIPTL 213
L + P L
Sbjct: 758 LEDPSEFETPAL 769
>gi|229892306 shugoshin-like 2 isoform 1 [Homo sapiens]
Length = 1265
Score = 33.5 bits (75), Expect = 0.30
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 89 GEKRGKVWVPKQKPLDPVLESVTLEPELE-EALANASDAELCDIAA--ILGMHTLMSNQQ 145
G K+G + Q+ +P+ E++ + EL+ AL+ + CD +LG+ ++N
Sbjct: 640 GLKKGNFFFKTQEDKEPISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNM- 698
Query: 146 YYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLER----IKNNDPKLEEVN 201
Y + S +NK+ V + T+ + N +E T++ + D ++ N
Sbjct: 699 -YPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGN 757
Query: 202 LNNIRNIPIPTL 213
L + P L
Sbjct: 758 LEDPSEFETPAL 769
>gi|229892197 shugoshin-like 2 isoform 3 [Homo sapiens]
Length = 1261
Score = 33.5 bits (75), Expect = 0.30
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
Query: 89 GEKRGKVWVPKQKPLDPVLESVTLEPELE-EALANASDAELCDIAA--ILGMHTLMSNQQ 145
G K+G + Q+ +P+ E++ + EL+ AL+ + CD +LG+ ++N
Sbjct: 640 GLKKGNFFFKTQEDKEPISENIEVSKELQIPALSTRDNENQCDYRTQNVLGLQKQITNM- 698
Query: 146 YYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLER----IKNNDPKLEEVN 201
Y + S +NK+ V + T+ + N +E T++ + D ++ N
Sbjct: 699 -YPVQQNESKVNKKLRQKVNRKTEIISEVNHLDNDKSIEYTVKSHSLFLTQKDKEIIPGN 757
Query: 202 LNNIRNIPIPTL 213
L + P L
Sbjct: 758 LEDPSEFETPAL 769
>gi|23503285 leucine rich repeat containing 34 [Homo sapiens]
Length = 419
Score = 33.5 bits (75), Expect = 0.30
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 3/97 (3%)
Query: 216 YAEALKENSYVKKFSIVGTRSNDPVAYALAEMLKENKVLKTLNVESNFISGAGILRLVEA 275
+A L+ NS ++K + G + + MLKEN L L++ + I +GI +L +A
Sbjct: 186 FAAMLQINSSLEKLDL-GDCDLEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDA 244
Query: 276 LPYNTSLVEMKIDNQSQPLGNKVEMEIVSMLEKNATL 312
L N+SL +D + + + + +L+ N TL
Sbjct: 245 LYLNSSL--RYLDVSCNKITHDGMVYLADVLKSNTTL 279
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 32.7 bits (73), Expect = 0.52
Identities = 55/255 (21%), Positives = 105/255 (41%), Gaps = 29/255 (11%)
Query: 16 DEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKREELLDHLEKQA 75
D + G + E +T +++L ++ D L +K +T + F R ++LD L +Q
Sbjct: 66 DNVTGGM-ETSRQTYDDKLTAVESDLKKLGDQTGKKAISTNSELSTF-RSDILD-LRQQL 122
Query: 76 KEFKDREDLVPYTGEK---RGKVWVPKQKPLDPVLESVTLEPELEEALANASDAELCDIA 132
+E ++ T EK G V +Q L LE+ + A + + ++
Sbjct: 123 REITEKTSKNKDTLEKLQASGDALVDRQSQLKETLENNSFLITTVNKTLQAYNGYVTNLQ 182
Query: 133 AILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTDVEETLERIKN 192
+ L N Q + IMN LN + + Q + + + + D + ++RIKN
Sbjct: 183 QDTSV--LQGNLQNQMYSHNVVIMNLNNLN-LTQVQQRNLITNLQRSVDDTSQAIQRIKN 239
Query: 193 NDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVK-KFSIVGTRSNDPVAYALAEMLKEN 251
+ L++V + +A K+ ++K K + T + + A A A N
Sbjct: 240 DFQNLQQV---------------FLQAKKDTDWLKEKVQSLQTLAANNSALAKA----NN 280
Query: 252 KVLKTLNVESNFISG 266
L+ +N + N +G
Sbjct: 281 DTLEDMNSQLNSFTG 295
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 32.7 bits (73), Expect = 0.52
Identities = 74/363 (20%), Positives = 146/363 (40%), Gaps = 43/363 (11%)
Query: 5 RELEKYRDLD-EDEILGALTEEELRTLENELDELDPDNALLPAGLRQKD-------QTTK 56
RELE+ R L E E A EE L N+L+E L L++KD Q
Sbjct: 1212 RELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDLEQQKN 1271
Query: 57 APTGPFKR-----EELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVT 111
+R EELL +++ K+ ++ + +++ K+ + ++ + + +
Sbjct: 1272 KLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEIQYTCR 1331
Query: 112 LEPELEEALANASDAELCDIAAILGM---HTLMSNQQYYQALSSSSIMNKEGLNSVIKPT 168
E AL + A+ G+ H ++ Q + + N++ + + T
Sbjct: 1332 -----ENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKAEQDMRELT 1386
Query: 169 QYKPVPDEEPNSTDVEETL--ERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYV 226
E N+ +E+T E+ + KL+E N N +R + L+ + E Y
Sbjct: 1387 Y-------ELNALQLEKTSSEEKARLLKDKLDETN-NTLRCL---KLELERKDQAEKGYS 1435
Query: 227 KKFSIVGTRSNDPVAYALAEM-----LKENKVLKTLNVESNFISGAGILRLVEALPYNTS 281
++ +G + N A M LK+ K L +ES + R V+ + +
Sbjct: 1436 QQLRELGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHA 1495
Query: 282 LVEMKI---DNQSQPLGNKVEMEIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDL 338
+ E I ++Q ++ E+E + + ++ + LK + + + L+ A NND
Sbjct: 1496 VAEKNIQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHE-QLLQNIKAEKENNDK 1554
Query: 339 VRK 341
+++
Sbjct: 1555 IQR 1557
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 32.3 bits (72), Expect = 0.67
Identities = 55/264 (20%), Positives = 113/264 (42%), Gaps = 37/264 (14%)
Query: 15 EDEILGALTEEELR-----TLENELDELDPDNALLPAGLRQKDQTTKAPTGP-FKREELL 68
E ++ + E+ R +L+ ++ ++ N L A ++Q A T EEL
Sbjct: 547 EQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELH 606
Query: 69 DHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELE--EALANASDA 126
+ ++ K+ K ED + +R ++ +++ D + L+ E++ +ALAN A
Sbjct: 607 KVIAEKDKQIKQTEDSL---ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAA 663
Query: 127 ELCDIAAILG----------------MHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQY 170
++ + H + + + ++ L+ + + L S ++ Q
Sbjct: 664 AAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQN----KALKSEVQKLQ- 718
Query: 171 KPVPDEEPNSTDVEETLERIKNNDPKLEEV-NLNNIRNIPIPTLKAYAEALK--ENSYVK 227
+ E+PN VE+ + I+ D KL+ V L I + T + A++ +S K
Sbjct: 719 -TLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTK 777
Query: 228 KFSIVGTRSNDPVAYA-LAEMLKE 250
+ + + ND V++A L E LK+
Sbjct: 778 EVQDLKAKQNDQVSFASLVEELKK 801
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 32.0 bits (71), Expect = 0.88
Identities = 28/123 (22%), Positives = 53/123 (43%), Gaps = 12/123 (9%)
Query: 24 EEELRTLENELDELDPDNALLPAGLRQKD--------QTTKAPTGPFKREELLDHLEKQA 75
E +R LE EL+ NA G+R+ + QT + + ++L+D L+ +
Sbjct: 1818 EARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV 1877
Query: 76 KEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELEEALANASDAELCDIAAIL 135
K +K + + E++ + K + + L+ ++ E+ N A+ DI A
Sbjct: 1878 KAYKRQAE----EAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGAKQ 1933
Query: 136 GMH 138
MH
Sbjct: 1934 KMH 1936
>gi|63054866 leucine rich repeat containing 16A [Homo sapiens]
Length = 1326
Score = 31.6 bits (70), Expect = 1.2
Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
Query: 180 STDVEETLERIKNNDPKLEEVNLNNI-RNIPIPTLKAYAEALKENSYVKKFSIVGTRSND 238
STDV E + R+ + +LEE+ L N A A A NS + ++ G D
Sbjct: 231 STDVCEQILRVVSRSNRLEELVLENAGLRTDFAQKLASALAHNPNSGLHTINLAGNPLED 290
Query: 239 PVAYALA-EMLKENKVLKTLNVESNFISGAGILRLVEALPYN 279
+L+ + K K LK LN+ +S G+ L ++L N
Sbjct: 291 RGVSSLSIQFAKLPKGLKHLNLSKTSLSPKGVNSLSQSLSAN 332
>gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens]
Length = 841
Score = 31.6 bits (70), Expect = 1.2
Identities = 50/226 (22%), Positives = 96/226 (42%), Gaps = 32/226 (14%)
Query: 5 RELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTGPFKR 64
REL + + E+E+ G + EE+ RT EL+ L L A + D G F+R
Sbjct: 474 RELHEDKKRQEEELRGQIREEKART--RELETLQQTVEELQAQVHSMD----GAKGWFER 527
Query: 65 --EELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPLDPVLESVTLEPELEEALAN 122
+E + L++Q +E +E+ + E+ K++ L ++ + L
Sbjct: 528 RLKEAEESLQQQQQE---QEEALKQCREQHAAELKGKEEELQ----------DVRDQLEQ 574
Query: 123 ASDAELCDIAAILGMHTLMSNQQYYQALSSSSIMNKEGLNSVIKPTQYKPVPDEEPNSTD 182
A + C + I + Q+ + I+ K+G ++ +K + + + E +
Sbjct: 575 AQEERDCHLKTISSL-----KQEVKDTVDGQRILEKKG-SAALKDLK-RQLHLERKRADK 627
Query: 183 VEETLERIKNNDPK---LEEVNLNNIRNIPIPTLKAYAEALKENSY 225
++E L+ I N LEE+ L+ + N P T + ++ SY
Sbjct: 628 LQERLQDILTNSKSRSGLEELVLSEM-NSPSRTQTGDSSSISSFSY 672
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,174,346
Number of Sequences: 37866
Number of extensions: 605986
Number of successful extensions: 1884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 1794
Number of HSP's gapped (non-prelim): 185
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.