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Search of human proteins with 4506797
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506797 ataxin 7 isoform a [Homo sapiens]
(892 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506797 ataxin 7 isoform a [Homo sapiens] 1820 0.0
gi|189491742 ataxin 7 isoform b [Homo sapiens] 1810 0.0
gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens] 489 e-138
gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens] 372 e-102
gi|93277115 ataxin 7-like 2 [Homo sapiens] 263 4e-70
gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens] 120 4e-27
gi|150170670 piccolo isoform 2 [Homo sapiens] 70 7e-12
gi|150378539 piccolo isoform 1 [Homo sapiens] 70 7e-12
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 60 9e-09
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo... 58 4e-08
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo... 58 4e-08
gi|161016767 mucin 21 [Homo sapiens] 57 8e-08
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 55 4e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 55 4e-07
gi|167736355 mucin 4 isoform a [Homo sapiens] 54 8e-07
gi|5174545 myocyte enhancer factor 2D [Homo sapiens] 53 1e-06
gi|28559039 mediator complex subunit 1 [Homo sapiens] 52 2e-06
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 52 2e-06
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 52 2e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 2e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 51 4e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 51 4e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 51 4e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 51 4e-06
gi|153792074 proline rich 12 [Homo sapiens] 51 4e-06
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 50 7e-06
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 50 1e-05
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 50 1e-05
gi|56549696 E1A binding protein p400 [Homo sapiens] 50 1e-05
gi|22325364 ubiquitin associated protein 2 [Homo sapiens] 50 1e-05
>gi|4506797 ataxin 7 isoform a [Homo sapiens]
Length = 892
Score = 1820 bits (4713), Expect = 0.0
Identities = 892/892 (100%), Positives = 892/892 (100%)
Query: 1 MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP
Sbjct: 1 MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
Query: 61 EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120
EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG
Sbjct: 61 EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120
Query: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180
KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV
Sbjct: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180
Query: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240
PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP
Sbjct: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240
Query: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300
IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL
Sbjct: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300
Query: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360
PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR
Sbjct: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360
Query: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420
SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR
Sbjct: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420
Query: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP
Sbjct: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
Query: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW
Sbjct: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
Query: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS
Sbjct: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
Query: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660
TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS
Sbjct: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660
Query: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS
Sbjct: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
Query: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780
SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP
Sbjct: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780
Query: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840
TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS
Sbjct: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840
Query: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP 892
PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP
Sbjct: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP 892
>gi|189491742 ataxin 7 isoform b [Homo sapiens]
Length = 945
Score = 1810 bits (4688), Expect = 0.0
Identities = 888/892 (99%), Positives = 889/892 (99%)
Query: 1 MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP
Sbjct: 1 MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
Query: 61 EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120
EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG
Sbjct: 61 EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFG 120
Query: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180
KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV
Sbjct: 121 KNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAV 180
Query: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240
PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP
Sbjct: 181 PPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHP 240
Query: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300
IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL
Sbjct: 241 IQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL 300
Query: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360
PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR
Sbjct: 301 PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTR 360
Query: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420
SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR
Sbjct: 361 SLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPR 420
Query: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP
Sbjct: 421 TSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
Query: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW
Sbjct: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
Query: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS
Sbjct: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
Query: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660
TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS
Sbjct: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS 660
Query: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS
Sbjct: 661 SVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSS 720
Query: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780
SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP
Sbjct: 721 SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP 780
Query: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840
TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS
Sbjct: 781 TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCS 840
Query: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQPKARP 892
PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQ + P
Sbjct: 841 PSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQDISSP 892
>gi|163937854 ataxin 7-like 1 isoform 1 [Homo sapiens]
Length = 861
Score = 489 bits (1260), Expect = e-138
Identities = 342/848 (40%), Positives = 465/848 (54%), Gaps = 102/848 (12%)
Query: 64 GPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNR 123
G G AMAT+ R +PSPE LG+ W+ W++A+KL D +L+E+ KE GK+R
Sbjct: 18 GTGKKQQEGRAMATLD--RKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSR 75
Query: 124 EVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKP-PLAVPP 182
EVM L +EDM +FG PAHDDFYLVVC+ CNQVVKPQ FQSH ERRH S +P P V P
Sbjct: 76 EVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCERRHGSMCRPSPSPVSP 135
Query: 183 TSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTR-PMHPI 241
S + SL + K + + S +SS+SK K+PK+ L + + + P
Sbjct: 136 AS--NPRTSLVQVKTKACLSGHHS--------ASSTSKPFKTPKDNLLTSSSKQHTVFPA 185
Query: 242 QQSRVPHGRIMTPSVKVEKIH--PKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPT 299
+ SR + P V +EKI K DG +K T + SS ++ P + KP
Sbjct: 186 KGSR-DKPCVPVPVVSLEKIPNLVKADGANVKMNSTTTTAVSASSTSSSAVSTPPLIKPV 244
Query: 300 L------PSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLD 353
L PSP +ILNGKG+ P T++KK ++ + N +RLSEREFDP+ HCGV+D +
Sbjct: 245 LMSKSVPPSPEKILNGKGI-LPTTIDKKHQNGTKNSNKPYRRLSEREFDPNKHCGVLDPE 303
Query: 354 TKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRD 413
TKKPCTRSLTCKTHSL+ RRAV GR+K+FD+LLAEHK K+REKE+ D + R+
Sbjct: 304 TKKPCTRSLTCKTHSLSHRRAVPGRKKQFDLLLAEHKAKSREKEV---KDKEHLLTSTRE 360
Query: 414 PHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPV 473
P+ +Q+ G E K +K +P LPRP A S+
Sbjct: 361 ILPSQSGPAQDSLLGSSGSSGPEPKVASPAKSRPPNSVLPRPSS--ANSISSSTSSNHSG 418
Query: 474 HESPHPPLPAT--EPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGR 531
H +P PPLP + ASRLSS+EGE D +ES EKLDC +S HHP+P +FC+FGSR +GR
Sbjct: 419 H-TPEPPLPPVGGDLASRLSSDEGEMDGADES-EKLDCQFSTHHPRPLAFCSFGSRLMGR 476
Query: 532 GYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIP-----PVPSTTSPISTRIPHRTNSVPT 586
GYYVFD RW+R R ALN MVEKHLN+Q+WKKIP P+PS + I+T +P P
Sbjct: 477 GYYVFDRRWDRFRFALNSMVEKHLNSQMWKKIPPAADSPLPSPAAHITTPVPASVLQ-PF 535
Query: 587 SQCGVSYLAAATVS---TSPVLLSSTCI-------SPNSKSVPAHGTTLNAQPAASGAMD 636
S YL +A +S TS +++S + SP+ ++ +H T A MD
Sbjct: 536 SNPSAVYLPSAPISSRLTSSYIMTSAMLSNAAFVTSPDPSALMSHTTAFPHVAATLSIMD 595
Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNAS 696
S+ +PS S + +V SP S KP K K+SKS + K+ S +
Sbjct: 596 -----------STFKAPSAVSPIPAVIPSP-SHKPSKTKTSKSSKVKDLS---------T 634
Query: 697 SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES-----FRKNCVAH---------S 742
S S KKRK S SSSSSSSSSS S+ S +KNCV + +
Sbjct: 635 RSDESPSNKKRKPQSST---SSSSSSSSSSLQTSLSSPLSGPHKKNCVLNASSALNSYQA 691
Query: 743 GPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDS-T 801
PPY +S+ ++ N + ++ + + SGR G PA+ ++++ + SSDS
Sbjct: 692 APPY-------NSLSVHNSNNGVSPLSAKLEPSGRTSLPGGPADIVRQVGAVGGSSDSCP 744
Query: 802 LSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPA 861
LS+ + +L + SH + S DK GKKRK S +SSSK K+ K+P
Sbjct: 745 LSVPSLALHAGDLSLASHNAVSSLPLSFDKSEGKKRKNS-------SSSSKACKITKMPG 797
Query: 862 VNNVHMKH 869
+N+VH K+
Sbjct: 798 MNSVHKKN 805
>gi|211971080 ataxin 7-like 1 isoform 3 [Homo sapiens]
Length = 738
Score = 372 bits (954), Expect = e-102
Identities = 270/697 (38%), Positives = 375/697 (53%), Gaps = 89/697 (12%)
Query: 214 ASSSSSKLLKSPKEKLQLRGNTR-PMHPIQQSRVPHGRIMTPSVKVEKIHP--KMDGTLL 270
++SS+SK K+PK+ L + + + P + SR + P V +EKI K DG +
Sbjct: 33 SASSTSKPFKTPKDNLLTSSSKQHTVFPAKGSR-DKPCVPVPVVSLEKIPNLVKADGANV 91
Query: 271 KSAVGPTCPATVSSLVKPGLNCPSIPKPTL------PSPGQILNGKGLPAPPTLEKKPED 324
K T + SS ++ P + KP L PSP +ILNGKG+ P T++KK ++
Sbjct: 92 KMNSTTTTAVSASSTSSSAVSTPPLIKPVLMSKSVPPSPEKILNGKGI-LPTTIDKKHQN 150
Query: 325 NSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDV 384
+ N +RLSEREFDP+ HCGV+D +TKKPCTRSLTCKTHSL+ RRAV GR+K+FD+
Sbjct: 151 GTKNSNKPYRRLSEREFDPNKHCGVLDPETKKPCTRSLTCKTHSLSHRRAVPGRKKQFDL 210
Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASK 444
LLAEHK K+REKE+ D + R+ P+ +Q+ G E K +K
Sbjct: 211 LLAEHKAKSREKEV---KDKEHLLTSTREILPSQSGPAQDSLLGSSGSSGPEPKVASPAK 267
Query: 445 PKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEE 502
+P LPRP A S+ H +P PPLP + ASRLSS+EGE D +E
Sbjct: 268 SRPPNSVLPRPSS--ANSISSSTSSNHSGH-TPEPPLPPVGGDLASRLSSDEGEMDGADE 324
Query: 503 SVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKK 562
S EKLDC +S HHP+P +FC+FGSR +GRGYYVFD RW+R R ALN MVEKHLN+Q+WKK
Sbjct: 325 S-EKLDCQFSTHHPRPLAFCSFGSRLMGRGYYVFDRRWDRFRFALNSMVEKHLNSQMWKK 383
Query: 563 IP-----PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS---TSPVLLSSTCI--- 611
IP P+PS + I+T +P P S YL +A +S TS +++S +
Sbjct: 384 IPPAADSPLPSPAAHITTPVPASVLQ-PFSNPSAVYLPSAPISSRLTSSYIMTSAMLSNA 442
Query: 612 ----SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM 667
SP+ ++ +H T A MD S+ +PS S + +V SP
Sbjct: 443 AFVTSPDPSALMSHTTAFPHVAATLSIMD-----------STFKAPSAVSPIPAVIPSP- 490
Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
S KP K K+SKS + K+ S + S S KKRK S SSSSSSSSSS
Sbjct: 491 SHKPSKTKTSKSSKVKDLS---------TRSDESPSNKKRKPQSST---SSSSSSSSSSL 538
Query: 728 SHSMES-----FRKNCVAH---------SGPPYPSTVTSSHSIGLNCVTNKANAVNVRHD 773
S+ S +KNCV + + PPY +S+ ++ N + ++ + +
Sbjct: 539 QTSLSSPLSGPHKKNCVLNASSALNSYQAAPPY-------NSLSVHNSNNGVSPLSAKLE 591
Query: 774 QSGRGPPTGSPAESIKRMSVMVNSSDS-TLSLGPFIHQSNELPVNSHGSFSHSHTPLDKL 832
SGR G PA+ ++++ + SSDS LS+ + +L + SH + S DK
Sbjct: 592 PSGRTSLPGGPADIVRQVGAVGGSSDSCPLSVPSLALHAGDLSLASHNAVSSLPLSFDKS 651
Query: 833 IGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKH 869
GKKRK S +SSSK K+ K+P +N+VH K+
Sbjct: 652 EGKKRKNS-------SSSSKACKITKMPGMNSVHKKN 681
>gi|93277115 ataxin 7-like 2 [Homo sapiens]
Length = 722
Score = 263 bits (673), Expect = 4e-70
Identities = 237/753 (31%), Positives = 324/753 (43%), Gaps = 116/753 (15%)
Query: 71 SAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCR 130
+AAAMA + ERR +PS + GQSW+ WVE + LP DG EL+ES K K + M L +
Sbjct: 7 AAAAMAAL-ERR-VPSLDDFAGQSWSSWVERADLPAADGAELEESSKNT-KKLDAMTLIK 63
Query: 131 EDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSK-----PPLAVPPTSV 185
EDM IFG CPAHDDFYLVVCN C+QVVKPQAFQ H ERRH SK PP P S
Sbjct: 64 EDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPASS 123
Query: 186 FSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSR 245
+ A GS ++SS +EK Q G+ H
Sbjct: 124 QKCHVVNGQGPACRAPGSTKTSS-----------------REKGQ--GSRSRGHQ----- 159
Query: 246 VPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQ 305
P K +K + G L K + G P S PG I +PS G
Sbjct: 160 --------PPEKTQKDNLCQPGGLTKDSPGKP-PMAPPSKEPPGRENIEI----IPSEGS 206
Query: 306 ILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCK 365
+G P EK+P K +++++ +E D + CGVI+ +TKK CTR LTCK
Sbjct: 207 SHWAEGSPP----EKEPSGTRLPPK-THRKMARKECDLNRQCGVINPETKKICTRLLTCK 261
Query: 366 THSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQ-- 423
HS+ QRR VQGR K FDVL+AE K +R+ E + + Q L P P + Q
Sbjct: 262 IHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVV 321
Query: 424 ---EPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPP 480
+ V ++ P+ A + P G + P P+ P
Sbjct: 322 AAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPM------P 375
Query: 481 LPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRW 540
T+ +S S EEG DD DCHY+ P+P +FCTFGSR + G YVF R
Sbjct: 376 RGGTQASSEESEEEGTSDDLHPPP---DCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRL 432
Query: 541 NRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
+R AL+ M+E+HL+ +WKKIPP + H NS P S + L+ ++
Sbjct: 433 DRFCSALSSMLERHLSTHMWKKIPPAAEPPA-------HLVNS-PLS----APLSPSSTG 480
Query: 601 TSPVLLSSTCISPNSKSV-PAHGTTLNAQPAASGAMDPVCS----MQSRQVSSSSSSPST 655
T P L T S+ P + + PA S ++ CS M Q +S +T
Sbjct: 481 TCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANT 540
Query: 656 PS-GLSSVPSSPMSRK---------------------PQKLKSSKSLRPKESSGNSTNCQ 693
PS S +P S S+ P LK + L P G + C+
Sbjct: 541 PSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEP-TGKGKPSGCR 599
Query: 694 NASSST--------SGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
S+ T +G G + K + PL S + + +E+ + H
Sbjct: 600 GLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLEN--RGAAGHPAKA 657
Query: 746 YPSTVTSSHSIG--LNCVTNKANAVNVRHDQSG 776
P+ S + + V +H Q+G
Sbjct: 658 LPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAG 690
>gi|23308753 ataxin 7-like 1 isoform 2 [Homo sapiens]
Length = 146
Score = 120 bits (302), Expect = 4e-27
Identities = 59/109 (54%), Positives = 75/109 (68%), Gaps = 2/109 (1%)
Query: 64 GPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNR 123
G G AMAT+ R +PSPE LG+ W+ W++A+KL D +L+E+ KE GK+R
Sbjct: 18 GTGKKQQEGRAMATLD--RKVPSPEAFLGKPWSSWIDAAKLHCSDNVDLEEAGKEGGKSR 75
Query: 124 EVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSS 172
EVM L +EDM +FG PAHDDFYLVVC+ CNQVVKPQ FQSH R+ +
Sbjct: 76 EVMRLNKEDMHLFGHYPAHDDFYLVVCSACNQVVKPQVFQSHCGRKQDN 124
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 70.5 bits (171), Expect = 7e-12
Identities = 172/817 (21%), Positives = 258/817 (31%), Gaps = 121/817 (14%)
Query: 1 MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
+SE + RA G+ AA + ++Q+ P +Q PP P R
Sbjct: 48 LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107
Query: 61 EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEF- 119
PG + + ++ P SP + S K T+L E K
Sbjct: 108 ----PGLSKSRTTDTFRSEQKLPGRSPSTI-----------SLKESKSRTDLKEEHKSSM 152
Query: 120 --GKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQ--VVKPQAFQSHYERRHSSSSK 175
G EV L + F P F L+ ++ +Q K Q + + K
Sbjct: 153 MPGFLSEVNALSAVSSVVNKFNP----FDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
Query: 176 PPLAVPPTSVFSFFPSLSKS---KGGSASGSNRSSSGGVLSASSSSSKLLKSPKE----- 227
PPL P + + G+ + + S + K ++ P +
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268
Query: 228 --KLQL-RGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTL----------LKSAV 274
KL L R +RP +Q+ + G + PS+ P T KS
Sbjct: 269 HAKLPLQRDASRPQ--TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 275 GPTCP-ATVSSLVKPGLNCPSIPKPTLPSPG------QILNGKGLPAPPTLEKKPEDNSN 327
GP P A S L KP P KP + PG Q L PA T +KP
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
Query: 328 NRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRF----- 382
K L + + P G T++ T + L G K
Sbjct: 387 GPKALAQPPGVGK-TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 383 -----------DVLLAEHKNKTREKELIRHPDSQQPPQP-LRDPHPAPPRTSQEPHQNPH 430
A+ T+ + P P QP P P P +++ P Q P
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Query: 431 GVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRL 490
P +P A KP P P +P P+QQ GSA P + P P P+ + +++
Sbjct: 506 STKPPPQQPGPA-KPSPQQPGSTKP---PSQQPGSA----KPSAQQPSPAKPSAQQSTKP 557
Query: 491 SSEEGEG-------------DDKEESVEKLDCHYSG------HHPQPASFCTFGSRQI-- 529
S+ G G + + K C H P+ A+F T Q
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 530 -------GRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
+ W L C + L + PVPS+ P P T
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNC--------QMKRALGGDLAPVPSSPQPKLKTAPVTTT 669
Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
S + + +P S P TL+ P+A P
Sbjct: 670 SAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGG 702
S+ + PS PS P + KP++ K K SS ++T + SS
Sbjct: 730 SK--PAPPKEPSVPSEQDKAPVA--DDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQ 784
Query: 703 SGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
S + K + PL S+ S S + + F +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821
Score = 41.2 bits (95), Expect = 0.004
Identities = 89/415 (21%), Positives = 145/415 (34%), Gaps = 70/415 (16%)
Query: 212 LSASSSSSKLLKSPKEKLQLRGNTRPMHPIQ-------QSRVPHGRIMTPSVKVEKIHPK 264
L +SSS++ P K+Q + + P++ QS P G ++P P
Sbjct: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825
Query: 265 MDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL----PSPGQILNGKGLPAPP---- 316
D ++ S GP+ + V P + PK P P KG P PP
Sbjct: 826 SDSKII-SHPGPSSESKGQKQVDP-VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 317 -------TLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSL 369
T ++ P+ +R+F ++ G I T P K+
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRF------------SLNLGSI---TDAP-------KSQPT 921
Query: 370 TQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPP-QPLRD-PHPAPPRTSQEPHQ 427
T + V G+ F + + P SQ P P++ P P+ P TSQ P +
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981
Query: 428 NPHGVIPSESK--PFVASKPKPHTPSL-PRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
+ P+ +K P P L P+ P + PPP+ +S
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS---LTA 1038
Query: 485 EPASRLSSEEGEGDDKEES---VEKLDCHYSGHHPQPASFCTFGSRQI-------GRGYY 534
EP + + E K ES + K + + P + CT Q+ +
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
Query: 535 VFDSRWNRLRCALNLMVEKHLNAQLW--KKIPPVPSTTSPISTRIPHRTNSVPTS 587
W LN ++ ++ QL +K+PP PS +P ++S T+
Sbjct: 1099 TEIQEW----LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTA 1149
Score = 41.2 bits (95), Expect = 0.004
Identities = 71/325 (21%), Positives = 121/325 (37%), Gaps = 58/325 (17%)
Query: 564 PPVPSTTSPISTRIPHR--TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
PP+P TSP T +P + T + P + + A T+ T+ VL S +P
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVL--------RSNGLPVT 2476
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
A P S+ S V + PS P P + + P + +
Sbjct: 2477 RICTTAPPPVP---PKPSSIPSGLVFTHRPEPSKP---PIAPKPVIPQLPTTTQKPTDIH 2530
Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAH 741
PK + + T+ + TS K +SPL HS+ SS S +S + V
Sbjct: 2531 PKPTGLSLTSSMTLNLVTS-ADYKLPSPTSPLSPHSNKSSPRFS------KSLTETYVVI 2583
Query: 742 SGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVN----- 796
+ P P T T S + Q+ P GSP++ + + + +
Sbjct: 2584 TLPSEPGTPTDSSA-----------------SQAITSWPLGSPSKDLVSVEPVFSVVPPV 2626
Query: 797 -------SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIG---KKRKCSPSSS-- 844
SS+ T + + + PV + SF + T + + + K + S + S
Sbjct: 2627 TAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTA 2686
Query: 845 -SINNSSSKPTKVAKVPAVNNVHMK 868
S+ SS T + A++N+H++
Sbjct: 2687 PSVGLSSISITIPPEPLALDNIHLE 2711
Score = 34.3 bits (77), Expect = 0.53
Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 12/119 (10%)
Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPH-------QNPHGV----- 432
L AE + + + HP S P+++ TS E Q P G
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385
Query: 433 IPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLS 491
+P++ +PF S + P PP P P PPP P P P P +L+
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444
Score = 33.9 bits (76), Expect = 0.69
Identities = 64/297 (21%), Positives = 100/297 (33%), Gaps = 70/297 (23%)
Query: 402 PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTP----------- 450
P PP P P P PP P +P I + K VAS TP
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465
Query: 451 SLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCH 510
++ R G P + PPPV PP P++ P+ + + E + + +
Sbjct: 2466 AVLRSNGLPVTR--ICTTAPPPV-----PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQ 2518
Query: 511 Y-------SGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
+ HP+P S LNL+
Sbjct: 2519 LPTTTQKPTDIHPKPTGLSLTSS------------------MTLNLVTSADYK------- 2553
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGV----------SYLAAATVSTSPVLLSSTCISP 613
+PS TSP+S PH S P + S T S++ ++S +
Sbjct: 2554 --LPSPTSPLS---PHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608
Query: 614 NSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSS----SSSPST-PSGLSSVPSS 665
SK + + + P + P+ S Q+ +S + S++P T PS + P+S
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTS 2665
Score = 30.4 bits (67), Expect = 7.7
Identities = 13/30 (43%), Positives = 13/30 (43%)
Query: 36 QQQQPPPPQPQRQQHPPPPPRRTRPEDGGP 65
Q PPPP P PPPPP P P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 70.5 bits (171), Expect = 7e-12
Identities = 172/817 (21%), Positives = 258/817 (31%), Gaps = 121/817 (14%)
Query: 1 MSERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRP 60
+SE + RA G+ AA + ++Q+ P +Q PP P R
Sbjct: 48 LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107
Query: 61 EDGGPGAASTSAAAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEF- 119
PG + + ++ P SP + S K T+L E K
Sbjct: 108 ----PGLSKSRTTDTFRSEQKLPGRSPSTI-----------SLKESKSRTDLKEEHKSSM 152
Query: 120 --GKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQ--VVKPQAFQSHYERRHSSSSK 175
G EV L + F P F L+ ++ +Q K Q + + K
Sbjct: 153 MPGFLSEVNALSAVSSVVNKFNP----FDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
Query: 176 PPLAVPPTSVFSFFPSLSKS---KGGSASGSNRSSSGGVLSASSSSSKLLKSPKE----- 227
PPL P + + G+ + + S + K ++ P +
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268
Query: 228 --KLQL-RGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTL----------LKSAV 274
KL L R +RP +Q+ + G + PS+ P T KS
Sbjct: 269 HAKLPLQRDASRPQ--TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326
Query: 275 GPTCP-ATVSSLVKPGLNCPSIPKPTLPSPG------QILNGKGLPAPPTLEKKPEDNSN 327
GP P A S L KP P KP + PG Q L PA T +KP
Sbjct: 327 GPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQP 386
Query: 328 NRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRF----- 382
K L + + P G T++ T + L G K
Sbjct: 387 GPKALAQPPGVGK-TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 383 -----------DVLLAEHKNKTREKELIRHPDSQQPPQP-LRDPHPAPPRTSQEPHQNPH 430
A+ T+ + P P QP P P P +++ P Q P
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Query: 431 GVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRL 490
P +P A KP P P +P P+QQ GSA P + P P P+ + +++
Sbjct: 506 STKPPPQQPGPA-KPSPQQPGSTKP---PSQQPGSA----KPSAQQPSPAKPSAQQSTKP 557
Query: 491 SSEEGEG-------------DDKEESVEKLDCHYSG------HHPQPASFCTFGSRQI-- 529
S+ G G + + K C H P+ A+F T Q
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 530 -------GRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
+ W L C + L + PVPS+ P P T
Sbjct: 618 CSLCGFNPNPHLTEVKEWLCLNC--------QMKRALGGDLAPVPSSPQPKLKTAPVTTT 669
Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
S + + +P S P TL+ P+A P
Sbjct: 670 SAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL 729
Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGG 702
S+ + PS PS P + KP++ K K SS ++T + SS
Sbjct: 730 SK--PAPPKEPSVPSEQDKAPVA--DDKPKQPKMVKPTTDLVSSSSATTKPDIPSS-KVQ 784
Query: 703 SGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
S + K + PL S+ S S + + F +
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAI 821
Score = 41.2 bits (95), Expect = 0.004
Identities = 89/415 (21%), Positives = 145/415 (34%), Gaps = 70/415 (16%)
Query: 212 LSASSSSSKLLKSPKEKLQLRGNTRPMHPIQ-------QSRVPHGRIMTPSVKVEKIHPK 264
L +SSS++ P K+Q + + P++ QS P G ++P P
Sbjct: 766 LVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825
Query: 265 MDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTL----PSPGQILNGKGLPAPP---- 316
D ++ S GP+ + V P + PK P P KG P PP
Sbjct: 826 SDSKII-SHPGPSSESKGQKQVDP-VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRP 883
Query: 317 -------TLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSL 369
T ++ P+ +R+F ++ G I T P K+
Sbjct: 884 TAGQTVPTPQQSPKPQEQSRRF------------SLNLGSI---TDAP-------KSQPT 921
Query: 370 TQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPP-QPLRD-PHPAPPRTSQEPHQ 427
T + V G+ F + + P SQ P P++ P P+ P TSQ P +
Sbjct: 922 TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK 981
Query: 428 NPHGVIPSESK--PFVASKPKPHTPSL-PRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
+ P+ +K P P L P+ P + PPP+ +S
Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKS---LTA 1038
Query: 485 EPASRLSSEEGEGDDKEES---VEKLDCHYSGHHPQPASFCTFGSRQI-------GRGYY 534
EP + + E K ES + K + + P + CT Q+ +
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
Query: 535 VFDSRWNRLRCALNLMVEKHLNAQLW--KKIPPVPSTTSPISTRIPHRTNSVPTS 587
W LN ++ ++ QL +K+PP PS +P ++S T+
Sbjct: 1099 TEIQEW----LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTA 1149
Score = 41.2 bits (95), Expect = 0.004
Identities = 71/325 (21%), Positives = 121/325 (37%), Gaps = 58/325 (17%)
Query: 564 PPVPSTTSPISTRIPHR--TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
PP+P TSP T +P + T + P + + A T+ T+ VL S +P
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVL--------RSNGLPVT 2476
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
A P S+ S V + PS P P + + P + +
Sbjct: 2477 RICTTAPPPVP---PKPSSIPSGLVFTHRPEPSKP---PIAPKPVIPQLPTTTQKPTDIH 2530
Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAH 741
PK + + T+ + TS K +SPL HS+ SS S +S + V
Sbjct: 2531 PKPTGLSLTSSMTLNLVTS-ADYKLPSPTSPLSPHSNKSSPRFS------KSLTETYVVI 2583
Query: 742 SGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVN----- 796
+ P P T T S + Q+ P GSP++ + + + +
Sbjct: 2584 TLPSEPGTPTDSSA-----------------SQAITSWPLGSPSKDLVSVEPVFSVVPPV 2626
Query: 797 -------SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIG---KKRKCSPSSS-- 844
SS+ T + + + PV + SF + T + + + K + S + S
Sbjct: 2627 TAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTA 2686
Query: 845 -SINNSSSKPTKVAKVPAVNNVHMK 868
S+ SS T + A++N+H++
Sbjct: 2687 PSVGLSSISITIPPEPLALDNIHLE 2711
Score = 34.3 bits (77), Expect = 0.53
Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 12/119 (10%)
Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPH-------QNPHGV----- 432
L AE + + + HP S P+++ TS E Q P G
Sbjct: 2326 LEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSS 2385
Query: 433 IPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLS 491
+P++ +PF S + P PP P P PPP P P P P +L+
Sbjct: 2386 LPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLT 2444
Score = 33.9 bits (76), Expect = 0.69
Identities = 64/297 (21%), Positives = 100/297 (33%), Gaps = 70/297 (23%)
Query: 402 PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTP----------- 450
P PP P P P PP P +P I + K VAS TP
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465
Query: 451 SLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCH 510
++ R G P + PPPV PP P++ P+ + + E + + +
Sbjct: 2466 AVLRSNGLPVTR--ICTTAPPPV-----PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQ 2518
Query: 511 Y-------SGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
+ HP+P S LNL+
Sbjct: 2519 LPTTTQKPTDIHPKPTGLSLTSS------------------MTLNLVTSADYK------- 2553
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGV----------SYLAAATVSTSPVLLSSTCISP 613
+PS TSP+S PH S P + S T S++ ++S +
Sbjct: 2554 --LPSPTSPLS---PHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608
Query: 614 NSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSS----SSSPST-PSGLSSVPSS 665
SK + + + P + P+ S Q+ +S + S++P T PS + P+S
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTS 2665
Score = 30.4 bits (67), Expect = 7.7
Identities = 13/30 (43%), Positives = 13/30 (43%)
Query: 36 QQQQPPPPQPQRQQHPPPPPRRTRPEDGGP 65
Q PPPP P PPPPP P P
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 60.1 bits (144), Expect = 9e-09
Identities = 93/382 (24%), Positives = 141/382 (36%), Gaps = 52/382 (13%)
Query: 407 PPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSA 466
PPQP PAPP + P P +P+ + + + P+P A + A
Sbjct: 2393 PPQP----SPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGA 2448
Query: 467 PIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKL---DCHYSGHHPQPASFCT 523
+ P P E +L E +++ E L + +G +P S +
Sbjct: 2449 --------KGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLS 2500
Query: 524 FGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS 583
GS G + W K + L ++ P P T S P +
Sbjct: 2501 LGSYPPAAGSSEPKAPW-----------PKATDGDLAQE--PGPGLTFEDSGN-PKSPDK 2546
Query: 584 VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
Q G A + S+S SS+ S +S S + G+ + D C
Sbjct: 2547 AQAEQDG----AEESESSSS---SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
R S++SS ++P+ SS SS SS S SS +S++ ++SSS+S S
Sbjct: 2600 RNCSAASSRAASPASSSSSSSS----------SSSSSSSSSSSSSSSSSSSSSSSSSSSS 2649
Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA-HSGPPYPSTVTSSHSIGLNCVT 762
+SS SSSSSSSSSSSS S +C + P P+ S+ + T
Sbjct: 2650 SSSSSSSS-----SSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT 2704
Query: 763 NKANAVNVRHDQSGRGPPTGSP 784
+A G+ P P
Sbjct: 2705 KQAGKARPSAHSPGKKTPAPQP 2726
Score = 52.0 bits (123), Expect = 2e-06
Identities = 92/397 (23%), Positives = 142/397 (35%), Gaps = 61/397 (15%)
Query: 401 HPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPA 460
+P + P PL + P + + P P V P P +P+ P CPA
Sbjct: 2352 NPTDEVPSTPLALEPSSTPGSKKSP---PEPVDKRAKAPKARPAPPQPSPAPPAFTSCPA 2408
Query: 461 QQGGSAPIDPPPVHESPHP--PLPATEPA---SRLSSEEG-----EGDDKEESVEKLDCH 510
+ A + P +P P +PAT P +R + E G ++ E + KLD H
Sbjct: 2409 PEP-FAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLD-H 2466
Query: 511 YSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTT 570
P+ + L++ + A W++ P +
Sbjct: 2467 EGVTSPKSK------------------------KAKEALLLREDPGAGGWQE----PKSL 2498
Query: 571 SPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPA 630
+ + P +S P + + P L +P S AQ
Sbjct: 2499 LSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPD--------KAQAE 2550
Query: 631 ASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
GA + S S SSSSSS S+ SG S + + K+ +G
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSG---------SETEGEEEGDKNGDGGCGTGGR- 2600
Query: 691 NCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTV 750
NC ASS + + +SS SSSSSSSSSSSS S S + + S S+
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
Query: 751 TSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAES 787
+SS S + T ++ D++ P G A++
Sbjct: 2661 SSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQA 2697
Score = 32.7 bits (73), Expect = 1.5
Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 9/82 (10%)
Query: 1 MSERAADDVRGEPRRAAAAAGGAAAAAARQQQ----QQQQQQQPPPPQPQRQQHPPPPPR 56
M A DV G P A A G A AARQ + ++ + P P+P PPPP
Sbjct: 283 MCNGGAGDV-GLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPP-- 339
Query: 57 RTRPEDGGPGAASTSAAAMATV 78
P G P + + A + TV
Sbjct: 340 --APPKGPPAPPAATPAGVYTV 359
Score = 32.0 bits (71), Expect = 2.6
Identities = 21/51 (41%), Positives = 28/51 (54%)
Query: 169 RHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSS 219
R+ S++ A P +S S S S S S+S S+ SSS S+SSSSS
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2650
Score = 31.6 bits (70), Expect = 3.4
Identities = 43/150 (28%), Positives = 60/150 (40%), Gaps = 33/150 (22%)
Query: 193 SKSKGG---------SASGSNRSSSGGVLSASSSSSKLLKSPK----EKLQL----RGNT 235
SK+ GG S G NR + L S SS+ K + K+++ RG
Sbjct: 1656 SKTSGGCGRYLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQP 1715
Query: 236 RPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS---AVGPTCPATVSSLVKPGLNC 292
+ H S V T S + E+ LK A GP+ SS + P L C
Sbjct: 1716 KSAHSPFASEVSSYSYNTDSEEDEEF--------LKDEWPAQGPS-----SSKLTPSLLC 1762
Query: 293 PSIPKPTLPSPGQILNGKGLPAPPTLEKKP 322
+ K + + G L +GL AP TL+ KP
Sbjct: 1763 SMVAKNSKAAGGPKLTKRGLAAPRTLKPKP 1792
Score = 30.8 bits (68), Expect = 5.9
Identities = 24/70 (34%), Positives = 31/70 (44%)
Query: 150 CNDCNQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSG 209
C+ + A S SSSS + +S S S S S S+S S+ SSS
Sbjct: 2602 CSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2661
Query: 210 GVLSASSSSS 219
S+SSSSS
Sbjct: 2662 SSSSSSSSSS 2671
Score = 30.4 bits (67), Expect = 7.7
Identities = 22/66 (33%), Positives = 31/66 (46%)
Query: 154 NQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLS 213
++ P + S SSSS + +S S S S S S+S S+ SSS S
Sbjct: 2607 SRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2666
Query: 214 ASSSSS 219
+SSSS+
Sbjct: 2667 SSSSST 2672
Score = 30.0 bits (66), Expect = 10.0
Identities = 23/68 (33%), Positives = 31/68 (45%)
Query: 152 DCNQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGV 211
+C+ A + SSSS + +S S S S S S+S S+ SSS
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2660
Query: 212 LSASSSSS 219
S+SSSSS
Sbjct: 2661 SSSSSSSS 2668
Score = 30.0 bits (66), Expect = 10.0
Identities = 22/58 (37%), Positives = 29/58 (50%)
Query: 171 SSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEK 228
SSSS + +S S S S S S+S S+ SSS S+SSSSS S ++
Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
sapiens]
Length = 1059
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/306 (27%), Positives = 110/306 (35%), Gaps = 48/306 (15%)
Query: 176 PPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNT 235
P PP S F P S+S S+ SSS S+SSSSS K P L
Sbjct: 75 PQYDYPPQSTFK--PKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGA 132
Query: 236 RPMHPIQQSRVPHGRIMTPSVKVEKI--HPKMDGTLLKS--AVGPTCPATVSSLVKPGLN 291
P P+ + P TP + + H + G L + A GP V PGL
Sbjct: 133 -PPPPLFDAAFP-----TPQWGIVDLSGHQHLFGNLKRGGPASGPG--------VTPGLG 178
Query: 292 CPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVID 351
P+ LP+P Q G PA + +D R+ K L ER F CGV
Sbjct: 179 APAGAPGPLPAPSQ--TPPGPPAAAACDPTKDDKGYFRRL--KYLMERRFP----CGV-- 228
Query: 352 LDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPL 411
C +S +H L Q V + ++ + + LIRH + P
Sbjct: 229 ------CQKSFKQSSH-LVQHMLVHSGERPYECGVC-GRTYNHVSSLIRHRRCHKDVPPA 280
Query: 412 RDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPA--QQGGSAPID 469
P P PH P G+ + A+ P + P P PA G +AP
Sbjct: 281 AGGPPQP-----GPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAG 335
Query: 470 ---PPP 472
PPP
Sbjct: 336 VGVPPP 341
Score = 32.0 bits (71), Expect = 2.6
Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 6/97 (6%)
Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASK 444
L EH P Q PPQP + PP+++ +P +PS S +S
Sbjct: 47 LYGEHAKAVAALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAE----VPSSSSSSSSSS 102
Query: 445 PKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPL 481
+ S + P+ PP +P PPL
Sbjct: 103 SSSSSSSSSSSSSSSQAKKPDPPL--PPAFGAPPPPL 137
Score = 31.6 bits (70), Expect = 3.4
Identities = 27/91 (29%), Positives = 35/91 (38%), Gaps = 10/91 (10%)
Query: 657 SGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVH 716
+ L P P PQ P+ + ++SSS+S S
Sbjct: 56 AALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSS---------- 105
Query: 717 SSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
SSSSSSSSSSSS + + A PP P
Sbjct: 106 SSSSSSSSSSSSQAKKPDPPLPPAFGAPPPP 136
Score = 30.0 bits (66), Expect = 10.0
Identities = 12/37 (32%), Positives = 23/37 (62%)
Query: 41 PPPQPQRQQHPPPPPRRTRPEDGGPGAASTSAAAMAT 77
PPPQP Q+ PP +P+ P ++S+S+++ ++
Sbjct: 68 PPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSS 104
>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
sapiens]
Length = 1059
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/306 (27%), Positives = 110/306 (35%), Gaps = 48/306 (15%)
Query: 176 PPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNT 235
P PP S F P S+S S+ SSS S+SSSSS K P L
Sbjct: 75 PQYDYPPQSTFK--PKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKKPDPPLPPAFGA 132
Query: 236 RPMHPIQQSRVPHGRIMTPSVKVEKI--HPKMDGTLLKS--AVGPTCPATVSSLVKPGLN 291
P P+ + P TP + + H + G L + A GP V PGL
Sbjct: 133 -PPPPLFDAAFP-----TPQWGIVDLSGHQHLFGNLKRGGPASGPG--------VTPGLG 178
Query: 292 CPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVID 351
P+ LP+P Q G PA + +D R+ K L ER F CGV
Sbjct: 179 APAGAPGPLPAPSQ--TPPGPPAAAACDPTKDDKGYFRRL--KYLMERRFP----CGV-- 228
Query: 352 LDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPL 411
C +S +H L Q V + ++ + + LIRH + P
Sbjct: 229 ------CQKSFKQSSH-LVQHMLVHSGERPYECGVC-GRTYNHVSSLIRHRRCHKDVPPA 280
Query: 412 RDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPA--QQGGSAPID 469
P P PH P G+ + A+ P + P P PA G +AP
Sbjct: 281 AGGPPQP-----GPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAG 335
Query: 470 ---PPP 472
PPP
Sbjct: 336 VGVPPP 341
Score = 32.0 bits (71), Expect = 2.6
Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 6/97 (6%)
Query: 385 LLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASK 444
L EH P Q PPQP + PP+++ +P +PS S +S
Sbjct: 47 LYGEHAKAVAALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAE----VPSSSSSSSSSS 102
Query: 445 PKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPL 481
+ S + P+ PP +P PPL
Sbjct: 103 SSSSSSSSSSSSSSSQAKKPDPPL--PPAFGAPPPPL 137
Score = 31.6 bits (70), Expect = 3.4
Identities = 27/91 (29%), Positives = 35/91 (38%), Gaps = 10/91 (10%)
Query: 657 SGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVH 716
+ L P P PQ P+ + ++SSS+S S
Sbjct: 56 AALPCAPGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSS---------- 105
Query: 717 SSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
SSSSSSSSSSSS + + A PP P
Sbjct: 106 SSSSSSSSSSSSQAKKPDPPLPPAFGAPPPP 136
Score = 30.0 bits (66), Expect = 10.0
Identities = 12/37 (32%), Positives = 23/37 (62%)
Query: 41 PPPQPQRQQHPPPPPRRTRPEDGGPGAASTSAAAMAT 77
PPPQP Q+ PP +P+ P ++S+S+++ ++
Sbjct: 68 PPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSS 104
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 57.0 bits (136), Expect = 8e-08
Identities = 75/326 (23%), Positives = 135/326 (41%), Gaps = 39/326 (11%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
STTS ++ + +S P+S + + ++ ++S ++ S + S + T +
Sbjct: 111 STTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSES 170
Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSS------KSLR 681
+SGA S S S +S++ ++ S +S +S + + S+ S
Sbjct: 171 STTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSES 230
Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAH 741
SSG ST + SS+ S G+G + S S++SS + ++++S S + +
Sbjct: 231 STTSSGASTATNSESSTPSSGAGTATNSES------STTSSGAGTATNSESSTVSSGI-- 282
Query: 742 SGPPYPSTVTSSH----SIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKR-MSVMVN 796
STVT+S S G N TN ++ SG T S + + S N
Sbjct: 283 ------STVTNSESSTPSSGANTATNSESSTT----SSGANTATNSDSSTTSSGASTATN 332
Query: 797 SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKV 856
S ST S G ++E S G+ + +++ G S +S++ N+ SS +
Sbjct: 333 SESSTTSSGASTATNSESSTTSSGASTATNS------GSSTTSSGTSTATNSESSTVSSG 386
Query: 857 AKVPAVNNVHMKHTGTIPGAQGLMNS 882
A + + + T GA NS
Sbjct: 387 ASTATTS----ESSTTSSGASTATNS 408
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 29/221 (13%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGV----------SYLAAATVSTSPVLLSSTCISPNSK- 616
STTS ++ + +S P+S G S AT S S + S NS+
Sbjct: 231 STTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSES 290
Query: 617 SVPAHG----TTLNAQPAASGA-----MDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM 667
S P+ G T + +SGA D + +++S S +T SG S+ +S
Sbjct: 291 STPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSES 350
Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
S +S +SG+ST S++T+ S +S SS++SS +S+
Sbjct: 351 S------TTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGAST 404
Query: 728 SHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAV 768
+ + ES + A + S+ TSS G N TN ++V
Sbjct: 405 ATNSESSTVSSGASTATNSESSTTSS---GANTATNSGSSV 442
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/247 (23%), Positives = 105/247 (42%), Gaps = 22/247 (8%)
Query: 614 NSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPS--TPSGLSSVPSSPMSRKP 671
N S A+ + AS A + S+ S VS+++ S S T +G+S V +S
Sbjct: 25 NETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTS 84
Query: 672 QKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSM 731
+ ++ + S + N+ SST+ NS SS+ SS +S++ +
Sbjct: 85 SGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNS------ESSTPSSGASTATNS 138
Query: 732 ESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESI-KR 790
+S + A + S+ TSS + + TN ++ SG T S + ++ R
Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEA---STATNSESSTT----SSGASTATNSESSTVSSR 191
Query: 791 MSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSS 850
S NS ST S G ++E S+G+ + +++ S +S++ N+ S
Sbjct: 192 ASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSE------SSTTSSGASTATNSES 245
Query: 851 SKPTKVA 857
S P+ A
Sbjct: 246 STPSSGA 252
Score = 40.4 bits (93), Expect = 0.007
Identities = 40/164 (24%), Positives = 71/164 (43%), Gaps = 9/164 (5%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
STTS ++ + +S +S + + ++ ++S ++ S + S + T +
Sbjct: 321 STTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSES 380
Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
+SGA S S +SS +S +T S S+V S + ++ S SSG
Sbjct: 381 STVSSGASTATTSESS--TTSSGASTATNSESSTVSSGAST-------ATNSESSTTSSG 431
Query: 688 NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSM 731
+T + SS TS GSG HS+S++ S + S+
Sbjct: 432 ANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGSL 475
Score = 33.9 bits (76), Expect = 0.69
Identities = 42/178 (23%), Positives = 73/178 (41%), Gaps = 10/178 (5%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
S +S S+ TNS S S + AT S S S + NS+S T+ A
Sbjct: 303 SESSTTSSGANTATNS--DSSTTSSGASTATNSESSTTSSGASTATNSESST---TSSGA 357
Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVP-SSPMSRKPQKLKSSKSLRPKESS 686
A + S S +S SS+ S+ + ++ SS S +S+S +
Sbjct: 358 STATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGA 417
Query: 687 GNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGP 744
+TN +++++S SG +S V S+ S +++ + H+ V+ + P
Sbjct: 418 STATNSESSTTS----SGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471
>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
Length = 796
Score = 54.7 bits (130), Expect = 4e-07
Identities = 42/94 (44%), Positives = 48/94 (51%), Gaps = 15/94 (15%)
Query: 16 AAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQH------------PPPPPRRTRPEDG 63
AAAAA AAAAAA+QQQQQQQQQQ Q Q+QQ P + E
Sbjct: 90 AAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERY 149
Query: 64 GPGAASTSAAAMATVGERR---PLPSPEVMLGQS 94
G AA+ +AAA A E+R P P V LG S
Sbjct: 150 GLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSS 183
Score = 34.7 bits (78), Expect = 0.41
Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 15/86 (17%)
Query: 11 GEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPP-----------QPQRQQHPPPPPRRTR 59
G R +AA AAAAAA +Q+ + + PPPP P P P+ T
Sbjct: 145 GLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPT- 203
Query: 60 PEDGGP---GAASTSAAAMATVGERR 82
PE+G P + S++A A+V RR
Sbjct: 204 PEEGPPELNRQSPNSSSAAASVASRR 229
Score = 30.0 bits (66), Expect = 10.0
Identities = 50/255 (19%), Positives = 99/255 (38%), Gaps = 36/255 (14%)
Query: 635 MDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQN 694
+D C M + S S +PS P G ++P + P ++ SLR +++S + +
Sbjct: 500 LDASCPMLPTALVSLSRAPSAPPGTGALPPA----APSGRGAAASLRKRKASPEPPD--S 553
Query: 695 ASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSH 754
A + G ++R+ ++ S + + S F A GPP P H
Sbjct: 554 AEGALKLGEEQQRQ-------QWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPH 606
Query: 755 SIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNEL 814
S N T PP +P M+ +++ +D TL + +
Sbjct: 607 S---NRTT----------------PPESAPQNGPSPMAALMSVAD-TLGTAHSPKDGSSV 646
Query: 815 PVNSHGSFSHSHTPLDKL-IGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGTI 873
+ + +S +P+ + +R+ + + +N + P A P ++ VH ++
Sbjct: 647 HSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAH-PGMDQVHPQNIPDS 705
Query: 874 PGA-QGLMNSSLLHQ 887
P A G + ++ H+
Sbjct: 706 PMANSGPLCCTICHE 720
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 54.7 bits (130), Expect = 4e-07
Identities = 65/214 (30%), Positives = 86/214 (40%), Gaps = 32/214 (14%)
Query: 565 PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSP----VLLSSTCISPNSKSVPA 620
PVPS S S + +T V SQ S A T S++ +L P+S
Sbjct: 2450 PVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEP 2509
Query: 621 HGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSP-------------- 666
+T QP+A A+ P +S SSSSSS S+ S SS SS
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 667 ------MSRKPQKLKSSKSL----RPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVH 716
+ R P + K RP E + +++SSS+S S +SS
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS---- 2625
Query: 717 SSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTV 750
SSSSSSSSSSSS S S + P P +
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2659
Score = 49.7 bits (117), Expect = 1e-05
Identities = 81/301 (26%), Positives = 122/301 (40%), Gaps = 59/301 (19%)
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
P PS + S R P ++ + + A SPV + S S+ + A T
Sbjct: 2411 PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPV---PSAFSDQSRCLIAQTT 2467
Query: 624 TL-NAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRP 682
+ +Q +SGA V++++SS +G+ SVP+ + P
Sbjct: 2468 PVAGSQSLSSGA-----------VATTTSSAGDHNGMLSVPAPGV--------------P 2502
Query: 683 KESSGN---STNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
G ST Q S+ + K+R++SS SSSSSSSSSSSS S S +
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSS-----SSSSSSSSSSSSSSSSSSSSSSG 2557
Query: 740 AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSD 799
+ S S++ + L V + A + GR PP +PA+ +R S +SS
Sbjct: 2558 SSSSDSEGSSLPVQPEVALKRVPSPTPAPK-EAVREGR-PPEPTPAKRKRRSSSSSSSSS 2615
Query: 800 STLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKV 859
S+ S S+ +S S S S S SSSS ++SSS P+
Sbjct: 2616 SSSS------SSSSSSSSSSSSSSSS--------------SSSSSSSSSSSSSPSPAKPG 2655
Query: 860 P 860
P
Sbjct: 2656 P 2656
Score = 46.6 bits (109), Expect = 1e-04
Identities = 75/307 (24%), Positives = 114/307 (37%), Gaps = 54/307 (17%)
Query: 567 PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPN-SKSVPAHGTTL 625
P+ S ++ R S T+ S A + S S T S + S + H T L
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTAL 291
Query: 626 --NAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPK 683
+ ASG + S ++S+ PS+P + PSSP K + K + RP
Sbjct: 292 AGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPS 351
Query: 684 ESSGNSTNCQNASSST------SGGSGKKRK----NSSPLLVHSSSSSSSSSSSSHSMES 733
S S+ + T GGS + + P+ S +S + S S E
Sbjct: 352 PSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEK 411
Query: 734 FRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSV 793
++ + S PP P S RH S P +PA R
Sbjct: 412 LPQSSSSESSPPSPQPTKVS-----------------RHASSSPESPKPAPAPGSHR--- 451
Query: 794 MVNSSDSTLSLGPFIHQSNELPVNSHG----SFSHSHTPLDKLIGKKRKCSPSSSSINNS 849
++SS ++ + SHG SHSHTP + +G+ R SP+++ S
Sbjct: 452 EISSSPTSKN-------------RSHGRAKRDKSHSHTP-SRRMGRSR--SPATAKRGRS 495
Query: 850 SSK-PTK 855
S+ PTK
Sbjct: 496 RSRTPTK 502
Score = 42.0 bits (97), Expect = 0.003
Identities = 93/428 (21%), Positives = 155/428 (36%), Gaps = 66/428 (15%)
Query: 371 QRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPH 430
++ + RR R L+ ++K + + +R S P P + PPR S+
Sbjct: 750 KKSRISSRRSRS---LSSPRSKAKSRLSLRRSLSGSSPCP-KQKSQTPPRRSRS------ 799
Query: 431 GVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRL 490
S+P S+ P P P +Q P SPHP + + P +
Sbjct: 800 ----GSSQPKAKSRTPPRRSRSSSSP--PPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG 853
Query: 491 SSEEGEGDDKEESVEKLDCHYSGHHPQ-----PASFCTFGSRQIGRGYYVFDSRWNRLRC 545
S + +++ + ++ C S P+ P+ GS V S R
Sbjct: 854 SITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSP----PRVKSSTPPRQSP 909
Query: 546 ALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVL 605
+ + + + A + + ++SP +R+ RT P VS + P
Sbjct: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT--TPRRSRSVSPCSNVESRLLPRY 967
Query: 606 LSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSS 665
S SP++K P + + SG++ P ++++ TP G PS
Sbjct: 968 SHSGSSSPDTKVKP----ETPPRQSHSGSISPYPKVKAQ----------TPPG----PSL 1009
Query: 666 PMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSG---------KKRKNSSPLLVH 716
S+ P + SK + G+ + C SST G K + +SP H
Sbjct: 1010 SGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSP--DH 1067
Query: 717 SSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSG 776
S +SS SHS ES + + P + +SS VT A+ +R D
Sbjct: 1068 RSDTSSPEVRQSHS-ESPSLQSKSQTSPKGGRSRSSSP------VTELASRSPIRQD--- 1117
Query: 777 RGPPTGSP 784
RG + SP
Sbjct: 1118 RGEFSASP 1125
Score = 39.7 bits (91), Expect = 0.013
Identities = 71/301 (23%), Positives = 110/301 (36%), Gaps = 32/301 (10%)
Query: 607 SSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPS-- 664
SS+ +SP++ V G + N Q +S +D V SR+ SSS+SSP GL PS
Sbjct: 1382 SSSELSPDA--VEKAGMSSN-QSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438
Query: 665 SPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSS 724
S P S + SG+S ++ + S G + + P + + S
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498
Query: 725 SSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSP 784
S SS + + C+ P S ++ T + R P
Sbjct: 1499 SPSSPELNN---KCLT------PQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKP 1549
Query: 785 AESIKRMSVMVNSSDSTLSLGPFIHQ------SNELPVNSHGSFSHSHTPLDKLIGKKRK 838
+ S + S +S DS + Q S E+ S S S + + K +
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPR 1609
Query: 839 CSPSSSSINNSSSKPTKVAKVPAV--------NNVHMKHTGTIPGAQGLMNSSLLHQPKA 890
+P + S ++SS +P K PA + K G P SS H PK+
Sbjct: 1610 AAPRAQSGSDSSPEP----KAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
Query: 891 R 891
R
Sbjct: 1666 R 1666
Score = 37.4 bits (85), Expect = 0.063
Identities = 67/269 (24%), Positives = 99/269 (36%), Gaps = 44/269 (16%)
Query: 607 SSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPS-- 664
SS C S++ P + ++QP A P S SSS P S PS
Sbjct: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR--------RSRSSSSPPPKQKSKTPSRQ 833
Query: 665 SPMSRKPQ-KLKSSKSLRPKESSGNSTNCQNAS----------------------SSTSG 701
S S P K+KS R + N Q+ + S SG
Sbjct: 834 SHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG 893
Query: 702 GSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTS----SHSIG 757
S + K+S+P S S SSS ++ S R+ + S P PS VTS S
Sbjct: 894 SSPPRVKSSTPPR-QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 758 LNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVN 817
++ +N + + R+ SG + SP +K + S ++S P+ + P
Sbjct: 953 VSPCSNVESRLLPRYSHSG----SSSPDTKVKPETPPRQSHSGSIS--PYPKVKAQTPPG 1006
Query: 818 SHGSFSHSHTPLDKLIGKKRKCSPSSSSI 846
S S S P +K + P S S+
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLSL 1035
Score = 35.0 bits (79), Expect = 0.31
Identities = 43/181 (23%), Positives = 65/181 (35%), Gaps = 28/181 (15%)
Query: 170 HSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKL 229
HS +PP + S +L +K +S S+ SSS S+SSSSS S
Sbjct: 2503 HSDVGEPPASTGAQQP-SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSS 2561
Query: 230 QLRGNTRPMHP-IQQSRVP-----------HGRIMTPSVKVEK---------IHPKMDGT 268
G++ P+ P + RVP GR P+ K +
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621
Query: 269 LLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNN 328
S+ + ++ SS + S P P P P + LP P + +K P +
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP------QALPKPASPKKPPPGERRS 2675
Query: 329 R 329
R
Sbjct: 2676 R 2676
Score = 34.3 bits (77), Expect = 0.53
Identities = 63/270 (23%), Positives = 100/270 (37%), Gaps = 26/270 (9%)
Query: 602 SPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSS 661
SPV S SP +S + T A+ S + P +SR + + S + S +
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRT-PARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687
Query: 662 VPSSPMSRKPQKLKS-SKSL--------RPKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
SR P++ +S S+SL R + G S + + + + R NSSP
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747
Query: 713 LLVHS------SSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKAN 766
+ S S S SS S + S S R++ S P + T KA
Sbjct: 748 EMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807
Query: 767 A-VNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHS 825
+ R +S PP +++ R S +S + G Q + + S + S
Sbjct: 808 SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGS---ITSPQANEQS 864
Query: 826 HTPLDKLIGKKRKCSPSSSSINNSSSKPTK 855
TP ++R C SS S P++
Sbjct: 865 VTP------QRRSCFESSPDPELKSRTPSR 888
Score = 33.9 bits (76), Expect = 0.69
Identities = 54/221 (24%), Positives = 81/221 (36%), Gaps = 44/221 (19%)
Query: 649 SSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRK 708
S + P SS P + P++ +SS S PK+ S + ++SSS K K
Sbjct: 790 SQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH----PKVK 845
Query: 709 NSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAV 768
+ +P S +S ++ S+ R++C S P + T S
Sbjct: 846 SGTP---PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPS--------------- 887
Query: 769 NVRHDQSGRGPP----TGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSH 824
RH SG PP + P +S R S + +S H + P S +
Sbjct: 888 --RHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP--SPSRVTS 943
Query: 825 SHTPLDKLIGKKRKCSPSSS---------SINNSSSKPTKV 856
TP + R SP S+ S + SSS TKV
Sbjct: 944 RTTP-----RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKV 979
Score = 33.9 bits (76), Expect = 0.69
Identities = 68/282 (24%), Positives = 98/282 (34%), Gaps = 43/282 (15%)
Query: 571 SPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPA 630
S + + RT S+ G S S SP S + SP+SK A T Q +
Sbjct: 1521 SSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSK---AKTRTPLRQRS 1577
Query: 631 ASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
SG+ P +SR S S S+P V P + + S S PK + +
Sbjct: 1578 RSGS-SPEVDSKSRLSPRRSRSGSSP----EVKDKPRAAPRAQSGSDSSPEPKAPAPRAL 1632
Query: 691 NCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTV 750
++ S S+S G G SP SSS+ SS H +S + S P
Sbjct: 1633 PRRSRSGSSSKGRG-----PSP-----EGSSSTESSPEHPPKSRTARRGSRSSP------ 1676
Query: 751 TSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQ 810
K + +S R P + + R S +SS T S P
Sbjct: 1677 -----------EPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP---- 1721
Query: 811 SNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSK 852
P + S P +K +R+ S SS +S +
Sbjct: 1722 ----PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRR 1759
Score = 33.9 bits (76), Expect = 0.69
Identities = 32/115 (27%), Positives = 40/115 (34%)
Query: 613 PNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQ 672
P+ P P + A S S SSSSSS S+ S SS SS S
Sbjct: 2580 PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639
Query: 673 KLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
SS S P + +S G++R S + S S S S S
Sbjct: 2640 SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
Score = 32.7 bits (73), Expect = 1.5
Identities = 55/260 (21%), Positives = 83/260 (31%), Gaps = 29/260 (11%)
Query: 648 SSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKR 707
S SSSP SS S K + +S PK + + S ST+ +R
Sbjct: 200 SESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRR 259
Query: 708 KNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGP------------PY--PSTVTSS 753
+ S +SSS +S S S + +A P P+ P T ++
Sbjct: 260 AHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQ 319
Query: 754 HSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNE 813
T + ++ D+ + P+ S +R S GP
Sbjct: 320 RPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSST-----------GPEPPAPTP 368
Query: 814 LPVNSHGSFSHSHTPLDKL-IGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTGT 872
L HG S PL + ++ PS +S S P K+P ++
Sbjct: 369 LLAERHGG---SPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425
Query: 873 IPGAQGLMNSSLLHQPKARP 892
P SS PK P
Sbjct: 426 QPTKVSRHASSSPESPKPAP 445
Score = 32.3 bits (72), Expect = 2.0
Identities = 109/496 (21%), Positives = 154/496 (31%), Gaps = 88/496 (17%)
Query: 167 ERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPK 226
+RR S+S P + S S+ + S RS + LS S S PK
Sbjct: 738 QRRSRSNSSPEMK----------KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPK 787
Query: 227 EKLQL---RGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVS 283
+K Q R + P +SR P R + S K K S+ P
Sbjct: 788 QKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH------ 841
Query: 284 SLVKPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDP 343
P + T P G I + P+ N + + E DP
Sbjct: 842 ---------PKVKSGTPPRQGSITS-------------PQANEQSVTPQRRSCFESSPDP 879
Query: 344 DIHCGVIDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPD 403
++ ++ C+ S + S T R R + K K R
Sbjct: 880 ELKSRT---PSRHSCSGSSPPRVKSSTPPRQSPSRSSS-----PQPKVKAIISPRQRSHS 931
Query: 404 SQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQG 463
P P R PR S+ +P + S P S +P P P +Q
Sbjct: 932 GSSSPSPSRVTSRTTPRRSRSV--SPCSNVESRLLPRY-SHSGSSSPDTKVKPETPPRQS 988
Query: 464 GSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFC- 522
S I P P ++ PP P+ + +E D +S P S C
Sbjct: 989 HSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSC-----------PGSLSLCA 1037
Query: 523 -TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRT 581
S G Y+ S L L + + P S TS R H
Sbjct: 1038 GVKSSTPPGESYFGVSS--------LQLKGQSQTS-------PDHRSDTSSPEVRQSHSE 1082
Query: 582 NSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSM 641
+ S+ S + S+SPV T ++ S G +A P M P
Sbjct: 1083 SPSLQSKSQTSPKGGRSRSSSPV----TELASRSPIRQDRG-EFSASPMLKSGMSP---E 1134
Query: 642 QSRQVSSSSSSPSTPS 657
QSR S SSS P+ S
Sbjct: 1135 QSRFQSDSSSYPTVDS 1150
Score = 32.0 bits (71), Expect = 2.6
Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 15/84 (17%)
Query: 434 PSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDP---------PPVHESPHPPLPAT 484
PS +KP + PKP +P P PPG + PID PV P P+
Sbjct: 2649 PSPAKPGPQALPKPASPKKP-PPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Query: 485 EPASRLSSEEG-----EGDDKEES 503
SSE G GD + S
Sbjct: 2708 RDQQSSSSERGSRRGQRGDSRSPS 2731
Score = 31.2 bits (69), Expect = 4.5
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 159 PQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSS 218
P+ + +RR SSSS +S S S S S S+S S+ SSS S+SSS
Sbjct: 2596 PEPTPAKRKRRSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
Query: 219 SKLLKSPKEKLQLRGNTRPMHPIQQSRVP 247
S P+ + +P ++SR P
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPGERRSRSP 2678
Score = 30.8 bits (68), Expect = 5.9
Identities = 39/179 (21%), Positives = 58/179 (32%), Gaps = 37/179 (20%)
Query: 353 DTKKPCTRSLTCKTHSLT----QRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPP 408
DT + +RS KTH+ GRR D +E P
Sbjct: 273 DTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE-------------------P 313
Query: 409 QPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPH--------TPSLPRPPGCPA 460
P+ P T+ + +P+ + K A++P P P P P
Sbjct: 314 GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373
Query: 461 QQGGSAPIDPPPVHESP-HPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQP 518
G P+ P+ + P +PP A+ R + E + S E S PQP
Sbjct: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES-----SPPSPQP 427
Score = 30.8 bits (68), Expect = 5.9
Identities = 17/76 (22%), Positives = 36/76 (47%), Gaps = 4/76 (5%)
Query: 16 AAAAAGGAAAAAARQQQQQQQQQQPPP---PQPQRQQHPPPPPRRTR-PEDGGPGAASTS 71
+++++ ++++++ +P P P+P + PPP RR+R P +
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSR 2689
Query: 72 AAAMATVGERRPLPSP 87
+ + + V RRP P P
Sbjct: 2690 SLSYSPVERRRPSPQP 2705
Score = 30.4 bits (67), Expect = 7.7
Identities = 99/507 (19%), Positives = 171/507 (33%), Gaps = 44/507 (8%)
Query: 388 EHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKP 447
EH K+R R P + P R+S+ + S +S P+
Sbjct: 1660 EHPPKSRTA---RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716
Query: 448 HTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKL 507
+ + PR P+ S+P +P S A+ P ++ +S G + S +
Sbjct: 1717 RSRTPPRHRRSPSV---SSP-EPAEKSRSSRRRRSASSPRTKTTSRRG----RSPSPKPR 1768
Query: 508 DCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVP 567
S + T R R R R + + + + P
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
++ S R R+ + PTS+ + + S +P S + SP + T L +
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSR----KRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
+ + PV +SR S S S +SP+SR+ + ++ R + S
Sbjct: 1885 RRRSRSRTSPVSRRRSR------SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938
Query: 688 NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
T + + S T + ++ ++ +P + S S +S + S
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 748 STVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPF 807
S VT S ++ + V R +S R PP + + S S L
Sbjct: 1999 SPVTRRRS------RSRTSPVTRRRSRS-RTPPAIRRRSRSRTPLLPRKRSRSRSPLAIR 2051
Query: 808 IHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHM 867
+ P + G S + +P +R+ + SSS + S+ P PA N
Sbjct: 2052 RRSRSRTPRTARGKRSLTRSP----PAIRRRSASGSSSDRSRSATP------PATRN--- 2098
Query: 868 KHTG--TIPGAQGLMNSSLLHQPKARP 892
H+G T P A S +P P
Sbjct: 2099 -HSGSRTPPVALNSSRMSCFSRPSMSP 2124
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 53.5 bits (127), Expect = 8e-07
Identities = 117/467 (25%), Positives = 178/467 (38%), Gaps = 62/467 (13%)
Query: 416 PAPPRTSQ----EPHQNPHGVIPSES-KPFVASKPKPHTPSLPRPPGCPAQQGGSAPI-- 468
P PP + P H + PS S K F + TP LP A G + P+
Sbjct: 937 PTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATP-LPVTYASSASTGHTTPLHV 995
Query: 469 -DPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSR 527
D V PLP T P+S + + S E S H P +F S
Sbjct: 996 TDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSE------STGHVTPLPVTSFSSA 1049
Query: 528 QIGRG--YYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVP 585
G V D+ L V +A P + TS ST H T+
Sbjct: 1050 STGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTG--HATSLPV 1107
Query: 586 TSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQ 645
T VS T T+P+ ++ T S + H T+L +S + +
Sbjct: 1108 TDTSSVS-----TGHTTPLPVTDT-----SSASTGHATSLPVTDTSSVSTGHTTPLHVTD 1157
Query: 646 VSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTN--CQNASSSTS 700
SS+S+ +TP + LSSV + + P SS S+G++T + SS+++
Sbjct: 1158 ASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSS------ASTGHATPLLVTDTSSAST 1211
Query: 701 GGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNC 760
G +++PL V +SS S+ ++S + H+ P P T TSS S G
Sbjct: 1212 G-------HATPLPVTDASSVSTDHATSLPVTIPSAASTGHT-TPLPVTDTSSASTGQAT 1263
Query: 761 VTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHG 820
+ +V + P T + + S ++ + +S S+ S G + LPV S
Sbjct: 1264 SLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTG----HATPLPVTSLS 1319
Query: 821 SFSHSHT-PLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVH 866
S S T PL SPSS+S +++ P V +V+ H
Sbjct: 1320 SASTGDTMPLP-------VTSPSSASTGDTT--PLPVTDASSVSTGH 1357
Score = 50.8 bits (120), Expect = 5e-06
Identities = 95/357 (26%), Positives = 149/357 (41%), Gaps = 67/357 (18%)
Query: 565 PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTT 624
P+P TSP S H T P G+S +A+T T+P+ ++ T S + H T
Sbjct: 3728 PLP-VTSPSSASTGHAT---PLPVTGLS--SASTGDTTPLPVTDT-----SSASTRHATP 3776
Query: 625 LNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPS-SPMSRKPQKLKSSKSLRPK 683
L +S + D + VSS+S+ +TP ++S S S P + + S+
Sbjct: 3777 LPVTDTSSASTDDTTRLPVTDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSV--- 3833
Query: 684 ESSGNSTNCQNAS-SSTSGG----------SGKKRKNSSPLLVHSSSSSSSSSSSSHSME 732
S+G++T+ S SS S G S +++PL V S+SS S+ ++ +
Sbjct: 3834 -STGHATSLPVTSRSSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVT 3892
Query: 733 SFRKNCVAHSGPPYPSTVTSSHSIGLNC---VTNKANAVNVRH---------DQSGRG-- 778
S H+ P P T TSS S G VTN A++++ H + RG
Sbjct: 3893 SPSSASTGHA-TPVPVTSTSSASTGDTTPLPVTN-ASSLSTGHATPLHVTSPSSASRGDT 3950
Query: 779 ---PPTGSPAESIKRMSVMVNSSDSTLSLG------------PFIHQSNELPVNSHGSFS 823
P T + + S + + +S S++S G Q+ LPV S S S
Sbjct: 3951 STLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVS 4010
Query: 824 HSH-TPLDKLIGKKRKCSPSSSSINNSSSKP-TKVAKVPAVNNVHMKHTGTIPGAQG 878
TPL I PSS+S +++S P T + V + + T T + G
Sbjct: 4011 TGDTTPLPVTI-------PSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTG 4060
Score = 47.8 bits (112), Expect = 5e-05
Identities = 76/324 (23%), Positives = 125/324 (38%), Gaps = 52/324 (16%)
Query: 565 PVPST-TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
P+P T S +ST H T+ TS VS T T+P+ ++S + + P H T
Sbjct: 2256 PLPVTDASSVSTG--HATSLPVTSLSSVS-----TGDTTPLPVTSPSSASTGHATPLHVT 2308
Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPST-PSGLSSVPSSPMSRKPQKLKSSKSLRP 682
++ PV S+ S ++ P T PS S+ ++P+ S+ P
Sbjct: 2309 DASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTP 2368
Query: 683 -------KESSGNST--NCQNASSSTSGG---------SGKKRKNSSPLLVHSSSSSSSS 724
SSG++T +ASS+++G S +++ L V SS+S+
Sbjct: 2369 LPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTG 2428
Query: 725 SSSSHSMESFRKNCVAHSGP---------------PYPSTVTSSHSIGLNCVTNKANAVN 769
++ + + H+ P P P T TSS S G +A +
Sbjct: 2429 DTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASS 2488
Query: 770 VRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPL 829
V + R P T + S + + + + S G + LPV + S S H
Sbjct: 2489 VSTGDTTRLPVTSPSSASTGHTTPLPVTDTPSASTG----DTTPLPVTNASSLSTRHAT- 2543
Query: 830 DKLIGKKRKCSPSSSSINNSSSKP 853
SPSS+S +++S P
Sbjct: 2544 -----SLHVTSPSSASTGHATSLP 2562
Score = 46.6 bits (109), Expect = 1e-04
Identities = 76/321 (23%), Positives = 127/321 (39%), Gaps = 40/321 (12%)
Query: 565 PVPSTTSPISTRIP--HRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPA-H 621
PV ST+S + + H T+ S V+ L + S++ ++ + ++ SV H
Sbjct: 3586 PVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGH 3645
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSK 678
T L A+S + + SS+S+ +TP + LSSV + + P SS
Sbjct: 3646 ATPLPVTDASSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDASSA 3705
Query: 679 SLR---------PKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSH 729
S P S T +S +S +G +++PL V SS+S+ ++
Sbjct: 3706 STGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTG----HATPLPVTGLSSASTGDTTPL 3761
Query: 730 SMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPP---TGSPAE 786
+ H+ P P T TSS S T + +V +G P T + +
Sbjct: 3762 PVTDTSSASTRHA-TPLPVTDTSSASTD---DTTRLPVTDVSSASTGHATPLPVTSTSSA 3817
Query: 787 SIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSS 845
S + + + S++S G + LPV S S S H TPL +SS
Sbjct: 3818 STGDTTPLPVTDTSSVSTG----HATSLPVTSRSSASTGHATPLP---------VTDTSS 3864
Query: 846 INNSSSKPTKVAKVPAVNNVH 866
++ + P V +V+ H
Sbjct: 3865 VSTGHATPLPVTSTSSVSTGH 3885
Score = 46.2 bits (108), Expect = 1e-04
Identities = 76/342 (22%), Positives = 129/342 (37%), Gaps = 51/342 (14%)
Query: 563 IPPVPST--TSPIS-TRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVP 619
IP ST T+P+ T + TS + +T T+P+ ++ST + P
Sbjct: 1445 IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP 1504
Query: 620 AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPST-PSGLSSVPSSPMSRKPQKLKSSK 678
H T+ ++ PV S+ S + P T PS S+ ++P+ S+
Sbjct: 1505 LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG 1564
Query: 679 SLRP-------KESSGNST--NCQNASSSTSGG---------SGKKRKNSSPLLVHSSSS 720
P S+G++T + SS++ G S +++PL V +SS
Sbjct: 1565 HTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSS 1624
Query: 721 SSSSSSSSHSMESFRKNCVAHSGP---------------PYPSTVTSSHSIGLNCVTNKA 765
+S+ ++ + + H+ P P P T TSS S G
Sbjct: 1625 ASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVT 1684
Query: 766 NAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHS 825
+ D + R P T + S + + + +S S++S G + LPV S S S
Sbjct: 1685 GLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTG----DTTPLPVTSPSSASTG 1740
Query: 826 H-TPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVH 866
H +PL +SS + + P V +V+ H
Sbjct: 1741 HASPL---------LVTDASSASTGQATPLPVTDTSSVSTAH 1773
Score = 46.2 bits (108), Expect = 1e-04
Identities = 78/320 (24%), Positives = 130/320 (40%), Gaps = 36/320 (11%)
Query: 565 PVPST-TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
P+P T TS ST H T S+P + +A+T +P+ + T S + H T
Sbjct: 2816 PLPVTDTSSASTG--HAT-SLPVTDTS----SASTGHATPLPDTDT-----SSASTGHAT 2863
Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPK 683
L +S ++ S+ SS S+ +TP ++S PSS + L + +
Sbjct: 2864 LLPVTDTSSASIGHATSLPVTDTSSISTGHATPLHVTS-PSSASTGHATPLPVTDTSSAS 2922
Query: 684 ESSGNSTNCQNASSSTSG---------GSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESF 734
N + + SS+++G S +++PL V S SS S+ ++ + S
Sbjct: 2923 TGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSP 2982
Query: 735 RKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVM 794
H+ P P T TSS S G + + + P T + + S + + +
Sbjct: 2983 SSASTGHT-TPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPL 3041
Query: 795 VNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPL---DKLIGKKRKCSP----SSSSI 846
+S S++S G + LPV S S S H TPL D + +P S SS+
Sbjct: 3042 PVTSLSSVSTG----DTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSV 3097
Query: 847 NNSSSKPTKVAKVPAVNNVH 866
+ + P V + + H
Sbjct: 3098 STGDTTPLPVTSPSSASTGH 3117
Score = 45.8 bits (107), Expect = 2e-04
Identities = 70/302 (23%), Positives = 122/302 (40%), Gaps = 27/302 (8%)
Query: 563 IPPVPST--TSPIS-TRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVP 619
IP ST T+P+ T + TS + +T T+P+ ++ST + P
Sbjct: 1237 IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP 1296
Query: 620 AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPST-PSGLSSVPSSPMSRKPQKLKSSK 678
H T+ ++ PV S+ S + P T PS S+ ++P+ S+
Sbjct: 1297 LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG 1356
Query: 679 SLRP---KESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFR 735
P ++S ST Q + S +++PL V S SS+S+ ++ +
Sbjct: 1357 HTTPLHVTDASSASTG-QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTS 1415
Query: 736 KNCVAHSGP---PYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMS 792
H+ P S+V++ H+ L A + + P T + + S + +
Sbjct: 1416 SASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG----HTTPLPVTDTSSASTGQAT 1471
Query: 793 VMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSSINNSSS 851
++ + S++S G + LPV S S S H TPL SPSS+S +++
Sbjct: 1472 SLLVTDTSSVSTG----DTTPLPVTSTSSASTGHVTPL-------HVTSPSSASTGHATP 1520
Query: 852 KP 853
P
Sbjct: 1521 LP 1522
Score = 45.8 bits (107), Expect = 2e-04
Identities = 74/336 (22%), Positives = 125/336 (37%), Gaps = 38/336 (11%)
Query: 565 PVPSTTSPIS---TRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
PV T+S + T +P S ++ L T S S + ++ S + H
Sbjct: 3138 PVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGH 3197
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSK 678
T L+ +S + + SS S+ +TP +GLSS + +R P SS
Sbjct: 3198 ATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSA 3257
Query: 679 SL-----RPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES 733
S P ++ + + + S +++PL V S+SS+S+ ++ + S
Sbjct: 3258 STGQATPLPVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTS 3317
Query: 734 FRKNCVAHSGP---------------PYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRG 778
H+ P P P T SS S G + + +
Sbjct: 3318 TSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSASTGDTSTL 3377
Query: 779 PPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPL---DKLIG 834
P TG+ + S + + + S++S G + LPV S S S TPL D
Sbjct: 3378 PVTGASSASTGHATPLPVTDTSSVSTG----HATPLPVTSLSSVSTGDTTPLPVTDASSA 3433
Query: 835 KKRKCSP----SSSSINNSSSKPTKVAKVPAVNNVH 866
+ +P S SS++ + P V +V+ H
Sbjct: 3434 STGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGH 3469
Score = 43.5 bits (101), Expect = 9e-04
Identities = 105/470 (22%), Positives = 159/470 (33%), Gaps = 66/470 (14%)
Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPID 469
P RD H T HG IP + + P P+L G S+P
Sbjct: 834 PSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTS 893
Query: 470 PPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQI 529
P SP + A + G D + +S P P S + G
Sbjct: 894 P---SASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSP 950
Query: 530 GRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQC 589
+ + K L P+P T + S H T P
Sbjct: 951 QTETHTLSPSGS----------GKTFTTALISNATPLPVTYAS-SASTGHTT---PLHVT 996
Query: 590 GVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSS 649
S ++ + PV SP+S S H T L +S + V + SS+
Sbjct: 997 DASSVSTGHATPLPV------TSPSSVST-GHTTPLPVTDTSSESTGHVTPLPVTSFSSA 1049
Query: 650 SSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNAS-SSTSGGSGKKRK 708
S+ STP ++ S+ S+G+ T S SS S G
Sbjct: 1050 STGDSTPLPVTDTSSA-------------------STGHVTPLPVTSLSSASTG------ 1084
Query: 709 NSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAV 768
+++PL V +SS+S+ ++S + H+ P P T TSS S G +
Sbjct: 1085 DTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHT-TPLPVTDTSSASTGHATSLPVTDTS 1143
Query: 769 NVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-T 827
+V + T + + S + + + +S S++S G + LPV S S S H T
Sbjct: 1144 SVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTG----DTTPLPVTSPSSASTGHAT 1199
Query: 828 PLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVHMKHTG-TIPGA 876
PL +SS + + P V +V+ H TIP A
Sbjct: 1200 PL---------LVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSA 1240
Score = 41.6 bits (96), Expect = 0.003
Identities = 65/285 (22%), Positives = 116/285 (40%), Gaps = 34/285 (11%)
Query: 596 AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPST 655
+A+ STSP ++ + ++S A G T ++PA+SG+ S + SSS +S +T
Sbjct: 757 SASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSR--TTSAGTATPSSSGASGTT 814
Query: 656 PSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS-------STSGGSGKKRK 708
PSG + +S + + SS R ++ ++T +AS+ ST S
Sbjct: 815 PSGSEGISTSGETTR----FSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPG 870
Query: 709 NSSPLLVHSSSS------SSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVT 762
P L +S++ SS +S S+ E+ + +A + T TS S ++ +
Sbjct: 871 TFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQT----QRTRTSRGSDTISLAS 926
Query: 763 NKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSF 822
+ + TG + + ++ + S T + I + LPV S
Sbjct: 927 QATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTA-LISNATPLPVTYASSA 985
Query: 823 SHSH-TPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKVPAVNNVH 866
S H TPL +SS++ + P V +V+ H
Sbjct: 986 STGHTTPLH---------VTDASSVSTGHATPLPVTSPSSVSTGH 1021
Score = 40.8 bits (94), Expect = 0.006
Identities = 100/427 (23%), Positives = 155/427 (36%), Gaps = 52/427 (12%)
Query: 449 TPSLPRPPGCPAQQGGSAPID---PPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVE 505
T LP A G + P+ P V PLP T P+S + G V
Sbjct: 3694 TTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSAST-----GHATPLPVT 3748
Query: 506 KLDCHYSGHH-PQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIP 564
L +G P P + + S + V D+ L V +A P
Sbjct: 3749 GLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSASTGHATP 3808
Query: 565 PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTT 624
++TS ST T +P + T S S +S ++ S + H T
Sbjct: 3809 LPVTSTSSASTG---DTTPLPVTD---------TSSVSTGHATSLPVTSRSSASTGHATP 3856
Query: 625 LNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS--RKPQKLKSSKSLRP 682
L +S + + SS S+ +TP ++S PSS + P + S+ S
Sbjct: 3857 LPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTS-PSSASTGHATPVPVTSTSS--- 3912
Query: 683 KESSGNST--NCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVA 740
S+G++T NASS ++G +++PL V S SS+S +S+ +
Sbjct: 3913 -ASTGDTTPLPVTNASSLSTG-------HATPLHVTSPSSASRGDTSTLPVTDASSASTG 3964
Query: 741 HSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDS 800
H+ P P T SS S G + + Q+ P T + S + + + S
Sbjct: 3965 HA-TPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTIPS 4023
Query: 801 TLSLGPFIHQSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKV 859
+ S G + LPV S S H TPL S+SS + + P V
Sbjct: 4024 SASSG----HTTSLPVTDASSVSTGHGTPLP---------VTSTSSASTGDTTPLPVTDT 4070
Query: 860 PAVNNVH 866
+ + H
Sbjct: 4071 SSASTGH 4077
Score = 40.4 bits (93), Expect = 0.007
Identities = 69/271 (25%), Positives = 115/271 (42%), Gaps = 35/271 (12%)
Query: 565 PVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTT 624
P+P TSP S H T + T A++VST +S ++ S H T
Sbjct: 2064 PLP-VTSPSSASTGHATPLLVTD--------ASSVSTGHA--TSLLVTDASSVSTGHATA 2112
Query: 625 LNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP---SGLSSVPSSPMSRKPQKLKSSKSLR 681
L+ A+S + + SS+S+ +TP + SSV + + P SS
Sbjct: 2113 LHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDTSS---- 2168
Query: 682 PKESSGNSTN--CQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCV 739
S+G++T+ + SS+++G +++PL V +SS+S+ ++ + S
Sbjct: 2169 --ASTGHATSLPVTDTSSASTG-------HATPLPVTDTSSASTGQATPLPVTSPSSAST 2219
Query: 740 AHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSD 799
H+ P T TSS S G + + + P T + + S + + +S
Sbjct: 2220 GHA-IPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSL 2278
Query: 800 STLSLGPFIHQSNELPVNSHGSFSHSH-TPL 829
S++S G + LPV S S S H TPL
Sbjct: 2279 SSVSTG----DTTPLPVTSPSSASTGHATPL 2305
Score = 40.0 bits (92), Expect = 0.010
Identities = 100/495 (20%), Positives = 170/495 (34%), Gaps = 69/495 (13%)
Query: 408 PQPLRDPHPAPPR-TSQEPHQNPHGVIPSESKPFVASKPKP----HTPSLPRPPGCPAQQ 462
P P+ P A T+ P + V + P + P HT LP A +
Sbjct: 1536 PLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASK 1595
Query: 463 GGSAPI---DPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGH----- 514
G + P+ P PLP T+ +S GD V +GH
Sbjct: 1596 GDTTPLPVTSPSSASTGHTTPLPVTD-----TSSASTGDTTPLPVTNASSLSTGHATPLH 1650
Query: 515 ----------HPQPASFCTFGSRQIGRGYYVFDSRWNRLRC--ALNLMVEKHLNAQLWKK 562
H P + S G + + + L V +A +
Sbjct: 1651 VTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQA 1710
Query: 563 IPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVP--- 619
P ++ S +ST T +P + S +A+T SP+L++ + ++ P
Sbjct: 1711 TPLPVTSLSSVSTG---DTTPLPVT----SPSSASTGHASPLLVTDASSASTGQATPLPV 1763
Query: 620 --------AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKP 671
AH T L +S + D + VSS+S+ + P ++S PSS +
Sbjct: 1764 TDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTS-PSSASTGDT 1822
Query: 672 QKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSM 731
L + + S SS++SG S P+ + +SS S+ ++ +
Sbjct: 1823 TPLPVTDASSASTGDTTSLPVTIPSSASSG-----HTTSLPV---TDASSVSTGHATSLL 1874
Query: 732 ESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRM 791
+ + P P T T+S S G + +A +V + P T + S
Sbjct: 1875 VTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDT 1934
Query: 792 SVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSS 851
+ + +S S+ S G + LPV S H + +SS++ +
Sbjct: 1935 TPLPVTSPSSASSG----HTTPLPVTDASSVPTGHATSLPV--------TDASSVSTGHA 1982
Query: 852 KPTKVAKVPAVNNVH 866
P V +V+ H
Sbjct: 1983 TPLPVTDASSVSTGH 1997
Score = 40.0 bits (92), Expect = 0.010
Identities = 59/261 (22%), Positives = 99/261 (37%), Gaps = 15/261 (5%)
Query: 570 TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQP 629
T S H T+ + T VS T T+P+ ++ T + + P H T ++
Sbjct: 1860 TDASSVSTGHATSLLVTDASSVS-----TGDTTPLPVTDTNSASTGDTTPLHVTDASSVS 1914
Query: 630 AASGAMDPVCSMQSRQVSSSSSSPST-PSGLSSVPSSPM---SRKPQKLKSSKSLRPKES 685
PV S+ S ++ P T PS SS ++P+ + SL ++
Sbjct: 1915 TGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDA 1974
Query: 686 SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
S ST T S +++PL V +SS S+ ++ + S + P
Sbjct: 1975 SSVSTGHATPLPVTD-ASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDT-TP 2032
Query: 746 YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLG 805
P T TSS S G + + +V + P T + S + ++ + S++S G
Sbjct: 2033 LPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSVSTG 2092
Query: 806 PFIHQSNELPVNSHGSFSHSH 826
+ L V S S H
Sbjct: 2093 ----HATSLLVTDASSVSTGH 2109
Score = 39.7 bits (91), Expect = 0.013
Identities = 71/314 (22%), Positives = 119/314 (37%), Gaps = 37/314 (11%)
Query: 570 TSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQP 629
T+P+ P ++ T+ V+ T S S +S ++ S + H T+L
Sbjct: 2126 TTPLPVTSPSSASTGDTTPLPVT----DTSSVSTGHATSLPVTDTSSASTGHATSLPVTD 2181
Query: 630 AASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNS 689
+S + + SS+S+ +TP ++S S+ L + S S+G +
Sbjct: 2182 TSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTS---SASTGQA 2238
Query: 690 TNCQNAS-SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPS 748
T S SS S G +++PL V +SS S+ ++S + S + P P
Sbjct: 2239 TPLPVTSLSSASTG------DTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDT-TPLPV 2291
Query: 749 TVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPF- 807
T SS S G + +A + + P T + S + + +S S+ S G
Sbjct: 2292 TSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHAT 2351
Query: 808 -IH----------QSNELPVNSHGSFSHSH-TPLDKLIGKKRKCSPSSSSINNSSSKPTK 855
+H + LPV S S S H TPL +SS + + P
Sbjct: 2352 PLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLP---------VTDASSASTGDTTPLP 2402
Query: 856 VAKVPAVNNVHMKH 869
V + + H H
Sbjct: 2403 VTDTSSASTGHATH 2416
Score = 37.0 bits (84), Expect = 0.082
Identities = 67/325 (20%), Positives = 127/325 (39%), Gaps = 31/325 (9%)
Query: 563 IPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHG 622
+ PS ++ +T +P S +++ S + S S +S ++ S + H
Sbjct: 2515 VTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGHA 2574
Query: 623 TTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTP------SGLSSVPSSPMSRKPQKLKS 676
T L +S + + S+S+ +TP S S+ ++P+ S
Sbjct: 2575 TPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSASTGDTTPLPVTDTSSAS 2634
Query: 677 SKSLRP-------KESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSH 729
+ P S+G++T + +S +S +G +++PL V +SS S+ ++S
Sbjct: 2635 TGHATPLPVTNTSSVSTGHATPL-HVTSPSSASTG----HTTPLPVTDASSVSTGHATSL 2689
Query: 730 SMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIK 789
+ H+ P T+ SS S G +A +V + P T + + S
Sbjct: 2690 PVTDASSVFTGHA-TSLPVTIPSSASSGHTTPLPVTDASSVSTGHATSLPVTDASSVSTG 2748
Query: 790 RMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSH-TPL---DKLIGKKRKCSP---- 841
+ + + S++S G + LP+ S S S TPL D + +P
Sbjct: 2749 HATPLPVTDASSVSTG----HATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVT 2804
Query: 842 SSSSINNSSSKPTKVAKVPAVNNVH 866
S SS++ + P V + + H
Sbjct: 2805 SLSSVSTGDTTPLPVTDTSSASTGH 2829
Score = 37.0 bits (84), Expect = 0.082
Identities = 62/263 (23%), Positives = 102/263 (38%), Gaps = 40/263 (15%)
Query: 592 SYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSS 651
S + +T T+P+L++ S H T L +S + + SS+S+
Sbjct: 3445 SLSSVSTGDTTPLLVTDA-----SSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSAST 3499
Query: 652 SPSTPSGLSSVPS-SPMSRKPQKLKSSKSLRPKESSGNST--NCQNASSSTSGG------ 702
+TP ++S+ S S P + + S+ S+G++T + SS+++G
Sbjct: 3500 GQATPLPVTSLSSVSTGDTTPLLVTDASSV----STGHATPLPVTDTSSASTGDTTRLPV 3555
Query: 703 ---SGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGP--------------- 744
S ++PL V SSSSS ++ + S H P
Sbjct: 3556 TDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVT 3615
Query: 745 PYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSL 804
P P T TSS S G +A +V + P T + + S + + + S+ S
Sbjct: 3616 PLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSAST 3675
Query: 805 GPFIHQSNELPVNSHGSFSHSHT 827
G Q+ LPV S S S T
Sbjct: 3676 G----QATPLPVTSLSSVSTGDT 3694
Score = 32.0 bits (71), Expect = 2.6
Identities = 42/175 (24%), Positives = 72/175 (41%), Gaps = 29/175 (16%)
Query: 570 TSPISTRIPHRTNSVPTSQCGVSYLAAATVST---SPVLLSSTCISPNSKSVP------- 619
T+P+ IP +S T+ V+ A++VST +P+ ++ST + + P
Sbjct: 4014 TTPLPVTIPSSASSGHTTSLPVT--DASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS 4071
Query: 620 ----AHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLK 675
H T L +S + + +SS S+ +TP +SS S+
Sbjct: 4072 SASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSA-------STV 4124
Query: 676 SSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHS 730
SS S E+ G +T S T G G++ S P + S+ S++ H+
Sbjct: 4125 SSDSPLKMETPGMTT----PSLKTDG--GRRTATSPPPTTSQTIISTIPSTAMHT 4173
>gi|5174545 myocyte enhancer factor 2D [Homo sapiens]
Length = 521
Score = 52.8 bits (125), Expect = 1e-06
Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 4/96 (4%)
Query: 402 PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQ 461
P QQPPQP + P P P+ Q+P Q ++P + P PH + P
Sbjct: 378 PPQQQPPQP-QQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSPLPHVGAALTVTTHPHI 436
Query: 462 QGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEG 497
S P+ P SP PP PA PA+R E G+G
Sbjct: 437 SIKSEPVSPSR-ERSPAPPPPAVFPAAR--PEPGDG 469
Score = 38.5 bits (88), Expect = 0.028
Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 16 AAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPE 61
A ++ GG + QQ QQ QQP PQP +QQ PP P++ +P+
Sbjct: 349 AFSSPGGLSLGNVTAWQQPQQPQQPQQPQPPQQQ--PPQPQQPQPQ 392
Score = 35.0 bits (79), Expect = 0.31
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 8/45 (17%)
Query: 21 GGAAAAAARQQQQQQQQQQPPP--------PQPQRQQHPPPPPRR 57
G A QQ QQ QQ QPP PQPQ+ Q P PP++
Sbjct: 359 GNVTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQ 403
Score = 33.5 bits (75), Expect = 0.90
Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 28/168 (16%)
Query: 621 HGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQK------- 673
+G+T+ A A PV + S Q S+ S S TPS ++S + P PQ+
Sbjct: 131 YGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLSPQQPALQRNS 190
Query: 674 LKSSKSLRPKESS---GNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHS 730
+ RP + G N N + + G+G +SP L+ ++ +
Sbjct: 191 VSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANGN--------- 241
Query: 731 MESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRG 778
S K A S PP +HS L + K + + V Q+G+G
Sbjct: 242 --SLNKVIPAKSPPP------PTHSTQLGAPSRKPD-LRVITSQAGKG 280
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 52.4 bits (124), Expect = 2e-06
Identities = 66/269 (24%), Positives = 100/269 (37%), Gaps = 26/269 (9%)
Query: 613 PNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPS--TPSGLSSVPSSPMSRK 670
P S + HG + + S+ + +S + SPS P G S +SPM
Sbjct: 1153 PGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPV 1212
Query: 671 PQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHS 730
P SSK+ P S ++ SSS+ S +S L + SS+S ++SS S
Sbjct: 1213 PGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSS 1272
Query: 731 MESFRKNCVA---HSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAES 787
S + + G + + + L V +K ++H GP P +
Sbjct: 1273 FSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDK-----LKHGVVTSGPGGEDPLDG 1327
Query: 788 IKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSIN 847
+M V NSS H + S G F DK K K S S SS++
Sbjct: 1328 --QMGVSTNSSS---------HPMSSKHNMSGGEFQGKREKSDK---DKSKVSTSGSSVD 1373
Query: 848 NS--SSKPTKVAKVPAVNNVHMKHTGTIP 874
+S +S+ V + KH G P
Sbjct: 1374 SSKKTSESKNVGSTGVAKIIISKHDGGSP 1402
Score = 50.8 bits (120), Expect = 5e-06
Identities = 75/291 (25%), Positives = 116/291 (39%), Gaps = 18/291 (6%)
Query: 579 HRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPV 638
+R + PTS G +A S +P +++ I + +P GT + +P++
Sbjct: 1028 NRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPKITIQIPK-GTVMVGKPSSHSQYTSS 1086
Query: 639 CSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSK-SLRPKESSGNSTNCQNASS 697
S+ S S S S+ S +S S K + SSK S S G+S + Q+ +S
Sbjct: 1087 GSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNS 1146
Query: 698 STSGGSGKKRKNSSPLLVHSSSSSSSSSS-------SSHSMESFRKNCV--AHSGPPYPS 748
S SGG + SSP+ H SS SSS+ SS S K + +HS PP S
Sbjct: 1147 SQSGG----KPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGS 1202
Query: 749 TVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFI 808
+S + + A + SG +G+ + S + S + SS S P
Sbjct: 1203 DKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTP-- 1260
Query: 809 HQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKV 859
S+ S SFS S + + + S S N S + K+
Sbjct: 1261 -PSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKL 1310
Score = 36.6 bits (83), Expect = 0.11
Identities = 85/363 (23%), Positives = 128/363 (35%), Gaps = 64/363 (17%)
Query: 421 TSQEPHQNPHGVI-PSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHP 479
T +P P ++ PS SKP ++ PS RPPG GS + SP
Sbjct: 1170 TKMKPQGKPSSLMNPSLSKPNIS-------PSHSRPPG------GSDKL------ASPMK 1210
Query: 480 PLPATEPASRLSSEEGEGDD-------------KEESVEKLDCHYSGHHPQPASFCTFGS 526
P+P T P+S+ S G K S S P ++ CT S
Sbjct: 1211 PVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASS 1270
Query: 527 RQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPT 586
S N+ + ++ KK PS T+ I S P
Sbjct: 1271 SSFSSSGSSMSSSQNQHGSSKGKSPSRN------KK----PSLTAVIDKLKHGVVTSGPG 1320
Query: 587 SQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQV 646
+ + + ++S +SS N G + S S+ S +
Sbjct: 1321 GEDPLDGQMGVSTNSSSHPMSS---KHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKK 1377
Query: 647 SSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSL-RPKESSGNSTNCQNASSSTSG---- 701
+S S + + +G++ + S +K+ +L +P ESSG Q ASS G
Sbjct: 1378 TSESKNVGS-TGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLI 1436
Query: 702 -GSGKKRKNSSPLLVHSSS--------SSSSSSSSSHSMESFRKNCVAHSG-PPYPSTVT 751
GS K + SP HS S S S S SS + +S++ + + G P P T
Sbjct: 1437 SGSTPKHERGSP--SHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYST 1494
Query: 752 SSH 754
H
Sbjct: 1495 EKH 1497
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 52.0 bits (123), Expect = 2e-06
Identities = 106/512 (20%), Positives = 173/512 (33%), Gaps = 85/512 (16%)
Query: 405 QQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGG 464
+ PP A + S+ ++P +P P P P PP P
Sbjct: 1010 KMPPAEKASRIRAAEKVSRGDQESPDACLP------------PTVPEAPAPPQKPLNSQS 1057
Query: 465 SAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTF 524
+ PPP+ P LP+ +P R + ++G +E L HP+P
Sbjct: 1058 QKHLAPPPLLS---PLLPSIKPTVRKTRQDG---SQEAPEAPLSSELEPFHPKPKIRTRK 1111
Query: 525 GSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSV 584
SR A + E H + + + P P++ +TR +SV
Sbjct: 1112 SSRMTPFP-------------ATSAAPEPHPSTSTAQPVTPKPTSQ---ATRSRTNRSSV 1155
Query: 585 PTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDP---VCSM 641
T + V T+P L ST S P T + + S P V +
Sbjct: 1156 KTPE--------PVVPTAPELQPSTSTDQPVTSEPTSQVT-RGRKSRSSVKTPETVVPTA 1206
Query: 642 QSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQK-----LKSSKSLRPKESSGNSTNCQNAS 696
Q S+S+ P T S +R K + ++ L+P S+ +
Sbjct: 1207 LELQPSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266
Query: 697 SSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSI 756
+T G + + +V ++ S+S+ + P P++ T+
Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPV------------TPKPTSRTTRSRT 1314
Query: 757 GLNCVTNKANAV--------NVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFI 808
++ V V + DQ PT S MS V + +ST+ + P +
Sbjct: 1315 NMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMS-SVKNPESTVPIAPEL 1373
Query: 809 --HQSNELPV---------NSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVA 857
S E PV + S TP + L+ K PS+S+ + +PT A
Sbjct: 1374 PPSTSTEQPVTPEPTSRATRGRKNRSSGKTP-ETLVPTAPKLEPSTSTDQPVTPEPTSQA 1432
Query: 858 KVPAVNNVHMKHTGT-IPGAQGLMNSSLLHQP 888
N +K T +P A L S+ QP
Sbjct: 1433 TRGRTNRSSVKTPETVVPTAPELQPSTSTDQP 1464
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 52.0 bits (123), Expect = 2e-06
Identities = 62/257 (24%), Positives = 89/257 (34%), Gaps = 40/257 (15%)
Query: 416 PAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPP-VH 474
P PP PH + H P P+PH PP P + G +P DPPP +
Sbjct: 992 PLPPAHHHPPHHHHHHAPP----------PQPHHHHA-HPPHPPEMETGGSPDDPPPRLA 1040
Query: 475 ESPHPPL-------PATEPASRLSSEEGEGDDKEESVEKLDCHYSGHHPQPASFCTFGSR 527
P P L P+ P + S G S + Y P+ AS +
Sbjct: 1041 LGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPA 1100
Query: 528 QIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTR------IPHRT 581
+ GRG + L + Q +PP PS TSP S + P
Sbjct: 1101 RSGRG----------RKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEK 1150
Query: 582 NSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSM 641
NS+P + + ++ S S+ P G + P+ + AM PV
Sbjct: 1151 NSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPV--- 1207
Query: 642 QSRQVSSSSSSPSTPSG 658
S +P++PSG
Sbjct: 1208 --PPSPSPVPTPASPSG 1222
Score = 36.6 bits (83), Expect = 0.11
Identities = 85/392 (21%), Positives = 119/392 (30%), Gaps = 67/392 (17%)
Query: 405 QQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGG 464
Q PP+P + APP T H +PH + + AS P P L G +Q+
Sbjct: 1375 QPPPRPPSPRYEAPPPTPH--HHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEK- 1431
Query: 465 SAPIDPPPVHES------PHPP--------LPATEPASRLSSEEGEGDDKEESVEKLDCH 510
S P PP S P P L PA + E E+L H
Sbjct: 1432 SLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLH 1491
Query: 511 YSG-HHPQPASFCTFGS---RQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPV 566
+ QP + T G + G G R + + + L PP
Sbjct: 1492 VRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPA 1551
Query: 567 PSTT--------------------------SPISTRIPHRTNSVPTSQCGVSYLAAATVS 600
PS SP++ PH P + + V+
Sbjct: 1552 PSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVA 1611
Query: 601 TSPVLLSSTCISPNSKSVPAHGTTLNAQ-----PAASGAMDPVCSMQSRQVSSSSSSPST 655
+P L ST S S T A P G P + P T
Sbjct: 1612 AAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGT 1671
Query: 656 PSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLV 715
SG+ V S S P + SS S+ +S + + S+ GG S P L+
Sbjct: 1672 DSGIEEVDSRSSSDHPLETISS------ASTLSSLSAEGGGSAGGGGGAGAGVASGPELL 1725
Query: 716 HSSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
+ + + S + GPPYP
Sbjct: 1726 DTYVAYLDGQAFGGS---------STPGPPYP 1748
Score = 32.3 bits (72), Expect = 2.0
Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 20/114 (17%)
Query: 402 PDSQQPPQPLRDPHPAPPRTSQEP---HQNPHGVIPSESKPFVASKPKPHTPSLPRPPG- 457
PD+ P PL P PP + P + +S+ ++ P P PPG
Sbjct: 1593 PDTPAPATPL--PPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGP 1650
Query: 458 -CPAQQGGSAPI---DPPP----------VHESPHPPLPATEPASRLSSEEGEG 497
PA +AP DPPP S PL AS LSS EG
Sbjct: 1651 PAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEG 1704
Score = 32.0 bits (71), Expect = 2.6
Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Query: 13 PRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSA 72
P RAA+AA A + R ++ +Q +PQ+ PP P T P A+
Sbjct: 1088 PPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSP------ASPQPP 1141
Query: 73 AAMATVGERRPLPSPEVML 91
A+A E+ +P P +++
Sbjct: 1142 PAVAAPSEKNSIPIPTIII 1160
Score = 31.6 bits (70), Expect = 3.4
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Query: 172 SSSKPPLAVPPTSVFSFFPSLSKSKGGSASGSNRSS--SGGVLSASSSSSKLLKSPKEKL 229
++S +A+P VFS + S G SGS S S SS + + SP+
Sbjct: 437 ANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPR-GA 495
Query: 230 QLRGNTRPMHPIQQSRVPHGR 250
+ R +R HP R P GR
Sbjct: 496 RARSPSRGRHPEDAKRQPRGR 516
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 52.0 bits (123), Expect = 2e-06
Identities = 144/731 (19%), Positives = 230/731 (31%), Gaps = 135/731 (18%)
Query: 13 PRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSA 72
PRR ++ + + + + + + P P P++++ P P + +TS
Sbjct: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
Query: 73 AAMATVGERRPLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCRED 132
+ + V + P+P P K P + E KE + R +
Sbjct: 242 SDILKVPKPEPIPEP---------------KEPSPEKNSKKEKEKEKTRPRS-RSRSKSR 285
Query: 133 MPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSL 192
P+H ++ P+ S R PP +PP P
Sbjct: 286 SRTRSRSPSHTRPRRRH-RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP-------PPR 337
Query: 193 SKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMH---------PIQQ 243
+ RSS+ S+SSSSS +SP +K R ++ P P ++
Sbjct: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397
Query: 244 SRVPHGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVK-PGLNCPSIPKPTLPS 302
P P P+ KS V + T + K G P P P
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA-PK 456
Query: 303 PGQI--------LNGKGLPAPPTLEKKPEDNSNNRKFLNKRLS-----EREFDPDIHCGV 349
P ++ GK A +++ N + + S ER + G
Sbjct: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516
Query: 350 IDLDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQ 409
+ + +RS + + + +GRR+R + TR + R P PP+
Sbjct: 517 VGRRRRHSPSRSASPSPRKRQKETSPRGRRRR-----SPSPPPTRRR---RSPSPAPPPR 568
Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPID 469
R P P P R + P P P + + P P R P A
Sbjct: 569 RRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS 628
Query: 470 PPPVHESPH--PPLPATEPASR-----LSSEEGEGDDKEESVEKLDCHYSGHHPQPASFC 522
PPP H PP + P ++ LSS+ +G S + PQP
Sbjct: 629 PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTRE------ARSPQPN--- 679
Query: 523 TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
K+ P P R P ++
Sbjct: 680 --------------------------------------KRHSPSP------RPRAPQTSS 695
Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCIS--PNSKSVPAHGTTLNAQPAASGAMDPVCS 640
S P + G S S SP +S P K + + AAS + V
Sbjct: 696 SPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI---------KKAASPSPQSV-- 744
Query: 641 MQSRQVSSS---SSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASS 697
R+VSSS S SP + P SP+ + S ++ K++ + + +
Sbjct: 745 ---RRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
Query: 698 STSGGSGKKRK 708
S G GKK+K
Sbjct: 802 SDQEGGGKKKK 812
Score = 47.8 bits (112), Expect = 5e-05
Identities = 114/534 (21%), Positives = 175/534 (32%), Gaps = 87/534 (16%)
Query: 4 RAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDG 63
R+ VR R +A+ +G ++++++ + + PP P+R PP RR P
Sbjct: 340 RSRSPVRRRRRSSASLSGSSSSSSS------SRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
Query: 64 GPGAASTSAAAMATVGERRPLPSPEVM-LGQSWNLWVEASKLPGK----DGTELDESFKE 118
P + + R P+P+ + + V + GK GTE ES
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453
Query: 119 FGKNREVMGLCREDMPIFGFCPAHDDFYLVVCNDCNQVVKPQAFQSHYERRHSSSSKPPL 178
K R+V L + G A D + + Q QS + SSSS+
Sbjct: 454 APKPRKVE-LSESEEDKGGKMAAADSVQQ------RRQYRRQNQQSSSDSGSSSSSEDER 506
Query: 179 AVPPTSVFSFFPSLSKSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEK---------L 229
P S K G R S S S + SP+ +
Sbjct: 507 -----------PKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT 555
Query: 230 QLRGNTRPMHPIQQSRVP----HGRIMTPSVKVEKIHPKMDGTLLKSAVGPTCPATVSSL 285
+ R + P P ++ R P R +P + P+ ++ P+ P +
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615
Query: 286 VKPGLNCPSIPKPTLPSPGQILNGKGLP------APPTLEKKPEDNSNNRKFLNKRLSER 339
P P + PSP P +P T + P +S +RK + S R
Sbjct: 616 SPP----PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTR 671
Query: 340 EFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQR-RAVQGRRKRFDVLLAEHKNKTREKEL 398
E + P K HS + R RA Q V +
Sbjct: 672 E-------------ARSPQPN----KRHSPSPRPRAPQTSSSPPPVRRGASSS------- 707
Query: 399 IRHPDSQQPPQPLRDP------HPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSL 452
P +Q P P P P P + + +P V S V+ P+P
Sbjct: 708 ---PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764
Query: 453 PRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKEESVEK 506
P PP Q S P + P P+ P R S +EG G K++ +K
Sbjct: 765 PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP-PRNSDQEGGGKKKKKKKDK 817
Score = 35.4 bits (80), Expect = 0.24
Identities = 74/332 (22%), Positives = 112/332 (33%), Gaps = 75/332 (22%)
Query: 194 KSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMT 253
+ K S RS S + S S + SP + + R ++R +SR P +
Sbjct: 157 EEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSP-----S 211
Query: 254 PSVKVEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPGQILNGKGLP 313
P+ + ++ P++ +K AT +S + +PKP P
Sbjct: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDIL------KVPKPE-------------P 252
Query: 314 APPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTCKTHSLTQRR 373
P E PE NS K + + +P +RS + K+ S T+ R
Sbjct: 253 IPEPKEPSPEKNSKKEK--------------------EKEKTRPRSRSRS-KSRSRTRSR 291
Query: 374 AVQGRRKRFDVLLAEHKNKTREKELIRHPDSQ-------------QPPQPLRDPHPAPPR 420
+ R R H++++R R P + PP P +P R
Sbjct: 292 SPSHTRPR-----RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVR 346
Query: 421 TSQEPHQNPHGVIPSESKPFVAS---KPKPHTPSLPR------PPGCPAQQ--GGSAPID 469
+ + G S S S KP T S PR P P ++ S P
Sbjct: 347 RRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT 406
Query: 470 PPP-VHESPHPPLPATEPASRLSSEEGEGDDK 500
PPP SP P SR+S G K
Sbjct: 407 PPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGK 438
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 51.2 bits (121), Expect = 4e-06
Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)
Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
P + + P P PAP P T +EP + P P E P +P P TP
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 331
Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
P P P P + +AP P P +P P P T EPA + E KE
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 387
Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
PA T + K K
Sbjct: 388 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 411
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
P P SP +T+ P T A T P + +P + PA T
Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462
Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
T P P ++ + +P+TP L+ + P P P++L + P
Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522
Score = 48.9 bits (115), Expect = 2e-05
Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)
Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
G+ T S K +EK K K PT P ++ P L P P PT P
Sbjct: 166 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 224
Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
K P P T++ P K +P TK+P +
Sbjct: 225 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 277
Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
+ T+ A K E T +K P P P ++P P P+
Sbjct: 278 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 335
Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
+ P P E P KP P TP P P P + + +P P +P P P T
Sbjct: 336 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 392
Query: 485 EPASRLSSEE 494
++ +++E
Sbjct: 393 TKSAPTTTKE 402
Score = 41.6 bits (96), Expect = 0.003
Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)
Query: 213 SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
+A ++ KL + EKL +P + P T + P+
Sbjct: 482 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 536
Query: 273 AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
A P P + +P P P PT P KG AP TL K+P +
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 591
Query: 331 FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
K+ + +E P TK+P S TC K T + K +
Sbjct: 592 ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 638
Query: 390 KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
T K P + + P P PAP P T++ P P P E+ P
Sbjct: 639 PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 696
Query: 442 ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
+P P TP P P P S P +P +H+SP P E ++ + +
Sbjct: 697 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 754
Query: 495 GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
E KE V + +P T + R ++
Sbjct: 755 LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 811
Query: 552 EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
EK +++ V STT+ +T T T V+ +T +
Sbjct: 812 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 871
Query: 612 SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
P ++ + TT Q P + + + +V ++P+ S++P +P
Sbjct: 872 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 931
Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
SR + + + + RP ++ + N S +GG+
Sbjct: 932 SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 966
Score = 40.8 bits (94), Expect = 0.006
Identities = 61/284 (21%), Positives = 92/284 (32%), Gaps = 48/284 (16%)
Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSA 466
P PAP T P P E P +P P TP P P PA SA
Sbjct: 241 PTTPKEPAPTTTKSAP------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294
Query: 467 PIDP-PPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFC 522
P P P +P P P T EPA E KE + K + P P +
Sbjct: 295 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-- 352
Query: 523 TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
+K + P P +P +T+ P T
Sbjct: 353 ----------------------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT- 383
Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
P + +A T + P ++T +P + P+ TT +PA + +P +
Sbjct: 384 -TPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTP 439
Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
+ ++ P+ + P++ P K PKE++
Sbjct: 440 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483
Score = 40.8 bits (94), Expect = 0.006
Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)
Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
T KSA PT P + KP P P PT P K PAP T E P
Sbjct: 289 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 345
Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
K+ + +E P TK+P + T K+ T +
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405
Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
K E T ++ P P P + P P P+ P P E
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 457
Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
P KP P TP P P P P + + P P P
Sbjct: 458 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517
Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
+P P P T EPA KE + K + P P + T + G
Sbjct: 518 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577
Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
K KK P P +P +T+ P T PT+
Sbjct: 578 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
G + A T P + +P + PA T P + P +
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 676
Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
+S +P+TP + P++P P K P+ ++ +++
Sbjct: 677 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 729
Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
P +H S S+ S+ +N G P T
Sbjct: 730 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 769
Score = 32.3 bits (72), Expect = 2.0
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)
Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
T + TS G +A + S S+ ++P SK + P TT PA + +
Sbjct: 157 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 215
Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
P + S++ P TP+ + S P++P P KS+ + PKE + +T
Sbjct: 216 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 267
Score = 32.0 bits (71), Expect = 2.6
Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)
Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
P P +P +T+ P T S PT+ T+P + T + + P
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 324
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
T + A +P + ++ P+ + P++P P K
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 384
Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
PKE + +T ++ + K ++P
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 51.2 bits (121), Expect = 4e-06
Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)
Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
P + + P P PAP P T +EP + P P E P +P P TP
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 372
Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
P P P P + +AP P P +P P P T EPA + E KE
Sbjct: 373 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 428
Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
PA T + K K
Sbjct: 429 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 452
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
P P SP +T+ P T A T P + +P + PA T
Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503
Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
T P P ++ + +P+TP L+ + P P P++L + P
Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563
Score = 48.9 bits (115), Expect = 2e-05
Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)
Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
G+ T S K +EK K K PT P ++ P L P P PT P
Sbjct: 207 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 265
Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
K P P T++ P K +P TK+P +
Sbjct: 266 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 318
Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
+ T+ A K E T +K P P P ++P P P+
Sbjct: 319 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 376
Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
+ P P E P KP P TP P P P + + +P P +P P P T
Sbjct: 377 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 433
Query: 485 EPASRLSSEE 494
++ +++E
Sbjct: 434 TKSAPTTTKE 443
Score = 41.6 bits (96), Expect = 0.003
Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)
Query: 213 SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
+A ++ KL + EKL +P + P T + P+
Sbjct: 523 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 577
Query: 273 AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
A P P + +P P P PT P KG AP TL K+P +
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 632
Query: 331 FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
K+ + +E P TK+P S TC K T + K +
Sbjct: 633 ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 679
Query: 390 KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
T K P + + P P PAP P T++ P P P E+ P
Sbjct: 680 PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 737
Query: 442 ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
+P P TP P P P S P +P +H+SP P E ++ + +
Sbjct: 738 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 795
Query: 495 GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
E KE V + +P T + R ++
Sbjct: 796 LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 852
Query: 552 EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
EK +++ V STT+ +T T T V+ +T +
Sbjct: 853 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 912
Query: 612 SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
P ++ + TT Q P + + + +V ++P+ S++P +P
Sbjct: 913 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 972
Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
SR + + + + RP ++ + N S +GG+
Sbjct: 973 SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 1007
Score = 40.8 bits (94), Expect = 0.006
Identities = 61/284 (21%), Positives = 92/284 (32%), Gaps = 48/284 (16%)
Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSA 466
P PAP T P P E P +P P TP P P PA SA
Sbjct: 282 PTTPKEPAPTTTKSAP------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335
Query: 467 PIDP-PPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFC 522
P P P +P P P T EPA E KE + K + P P +
Sbjct: 336 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA-- 393
Query: 523 TFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTN 582
+K + P P +P +T+ P T
Sbjct: 394 ----------------------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT- 424
Query: 583 SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQ 642
P + +A T + P ++T +P + P+ TT +PA + +P +
Sbjct: 425 -TPKEPAPTTTKSAPTTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTP 480
Query: 643 SRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
+ ++ P+ + P++ P K PKE++
Sbjct: 481 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524
Score = 40.8 bits (94), Expect = 0.006
Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)
Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
T KSA PT P + KP P P PT P K PAP T E P
Sbjct: 330 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 386
Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
K+ + +E P TK+P + T K+ T +
Sbjct: 387 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446
Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
K E T ++ P P P + P P P+ P P E
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 498
Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
P KP P TP P P P P + + P P P
Sbjct: 499 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558
Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
+P P P T EPA KE + K + P P + T + G
Sbjct: 559 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618
Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
K KK P P +P +T+ P T PT+
Sbjct: 619 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
G + A T P + +P + PA T P + P +
Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 717
Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
+S +P+TP + P++P P K P+ ++ +++
Sbjct: 718 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 770
Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
P +H S S+ S+ +N G P T
Sbjct: 771 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 810
Score = 32.3 bits (72), Expect = 2.0
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)
Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
T + TS G +A + S S+ ++P SK + P TT PA + +
Sbjct: 198 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 256
Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
P + S++ P TP+ + S P++P P KS+ + PKE + +T
Sbjct: 257 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 308
Score = 32.0 bits (71), Expect = 2.6
Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)
Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
P P +P +T+ P T S PT+ T+P + T + + P
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 365
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
T + A +P + ++ P+ + P++P P K
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 425
Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
PKE + +T ++ + K ++P
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 456
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 51.2 bits (121), Expect = 4e-06
Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)
Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
P + + P P PAP P T +EP + P P E P +P P TP
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 424
Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
P P P P + +AP P P +P P P T EPA + E KE
Sbjct: 425 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 480
Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
PA T + K K
Sbjct: 481 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 504
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
P P SP +T+ P T A T P + +P + PA T
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555
Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
T P P ++ + +P+TP L+ + P P P++L + P
Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615
Score = 48.9 bits (115), Expect = 2e-05
Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)
Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
G+ T S K +EK K K PT P ++ P L P P PT P
Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 317
Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
K P P T++ P K +P TK+P +
Sbjct: 318 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 370
Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
+ T+ A K E T +K P P P ++P P P+
Sbjct: 371 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 428
Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
+ P P E P KP P TP P P P + + +P P +P P P T
Sbjct: 429 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 485
Query: 485 EPASRLSSEE 494
++ +++E
Sbjct: 486 TKSAPTTTKE 495
Score = 46.6 bits (109), Expect = 1e-04
Identities = 119/569 (20%), Positives = 183/569 (32%), Gaps = 69/569 (12%)
Query: 139 CPAHDDFYLVVCNDCN-----QVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLS 193
CP ++ F V N + + P + S KPP V S
Sbjct: 56 CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIE---SEE 112
Query: 194 KSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMT 253
++ S S + SSS S+SSS+ + +KS K R + + + + T
Sbjct: 113 ITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 172
Query: 254 PSVKV-EKIHPKMDGTLLKSAVGPTCPAT---VSSLVKPGLNCPSIPKPTLPSPGQILNG 309
P V ++ +D K T VS+ K P P+P+LP
Sbjct: 173 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 232
Query: 310 KGLPA--PPTLEKKPEDNSNNRKFLN---KRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
L T+E K +N + + K S +E DL T
Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 292
Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
K + T+ A+ ++ E + T KE P P PAP T
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTT-PKEPTPTTIKSAPTTP---KEPAPTTTKSA 348
Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSAPIDP-PPVHESPHPP 480
P P E P +P P TP P P PA SAP P P +P P
Sbjct: 349 P------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 402
Query: 481 LPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFD 537
P T EPA E KE + K + P P +
Sbjct: 403 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----------------- 445
Query: 538 SRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAA 597
+K + P P +P +T+ P T P + +A
Sbjct: 446 -------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT--TPKEPAPTTTKSAP 490
Query: 598 TVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPS 657
T + P ++T +P + P+ TT +PA + +P + + ++ P+ +
Sbjct: 491 TTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547
Query: 658 GLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
P++ P K PKE++
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETA 576
Score = 41.6 bits (96), Expect = 0.003
Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)
Query: 213 SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
+A ++ KL + EKL +P + P T + P+
Sbjct: 575 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 629
Query: 273 AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
A P P + +P P P PT P KG AP TL K+P +
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 684
Query: 331 FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
K+ + +E P TK+P S TC K T + K +
Sbjct: 685 ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 731
Query: 390 KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
T K P + + P P PAP P T++ P P P E+ P
Sbjct: 732 PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789
Query: 442 ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
+P P TP P P P S P +P +H+SP P E ++ + +
Sbjct: 790 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 847
Query: 495 GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
E KE V + +P T + R ++
Sbjct: 848 LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 904
Query: 552 EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
EK +++ V STT+ +T T T V+ +T +
Sbjct: 905 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 964
Query: 612 SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
P ++ + TT Q P + + + +V ++P+ S++P +P
Sbjct: 965 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1024
Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
SR + + + + RP ++ + N S +GG+
Sbjct: 1025 SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 1059
Score = 40.8 bits (94), Expect = 0.006
Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)
Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
T KSA PT P + KP P P PT P K PAP T E P
Sbjct: 382 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 438
Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
K+ + +E P TK+P + T K+ T +
Sbjct: 439 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498
Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
K E T ++ P P P + P P P+ P P E
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 550
Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
P KP P TP P P P P + + P P P
Sbjct: 551 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 610
Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
+P P P T EPA KE + K + P P + T + G
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670
Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
K KK P P +P +T+ P T PT+
Sbjct: 671 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 712
Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
G + A T P + +P + PA T P + P +
Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 769
Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
+S +P+TP + P++P P K P+ ++ +++
Sbjct: 770 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 822
Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
P +H S S+ S+ +N G P T
Sbjct: 823 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 862
Score = 33.1 bits (74), Expect = 1.2
Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 3/110 (2%)
Query: 649 SSSSPSTPSGLSSVPSSPMSRKPQ---KLKSSKSLRPKESSGNSTNCQNASSSTSGGSGK 705
SS PSG S S R P+ K K+ K + +E + + +N SS+S S
Sbjct: 74 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 133
Query: 706 KRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHS 755
+ +S+++ ++ +KN P P V + S
Sbjct: 134 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 183
Score = 32.3 bits (72), Expect = 2.0
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)
Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
T + TS G +A + S S+ ++P SK + P TT PA + +
Sbjct: 250 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 308
Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
P + S++ P TP+ + S P++P P KS+ + PKE + +T
Sbjct: 309 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 360
Score = 32.0 bits (71), Expect = 2.6
Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)
Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
P P +P +T+ P T S PT+ T+P + T + + P
Sbjct: 365 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 417
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
T + A +P + ++ P+ + P++P P K
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 477
Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
PKE + +T ++ + K ++P
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 51.2 bits (121), Expect = 4e-06
Identities = 67/300 (22%), Positives = 92/300 (30%), Gaps = 68/300 (22%)
Query: 402 PDSQQPPQPLRDPHPAP------PRTSQEP----HQNPHGVIPSESKPFVASKPKPHTPS 451
P + + P P PAP P T +EP + P P E P +P P TP
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 465
Query: 452 LPRP------PGCPAQQGGSAPIDPPPVHESPHPPLPAT--EPASRLSSEEGEGDDKEES 503
P P P P + +AP P P +P P P T EPA + E KE
Sbjct: 466 EPAPTTKEPAPTTPKEPAPTAPKKPAPT--TPKEPAPTTPKEPAPTTTKEPSPTTPKE-- 521
Query: 504 VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKI 563
PA T + K K
Sbjct: 522 --------------PAPTTTKSAP----------------------TTTKEPAPTTTKSA 545
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
P P SP +T+ P T A T P + +P + PA T
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKE---------PAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596
Query: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLS-SVPSSPMSRKPQKLKSSKSLRP 682
T P P ++ + +P+TP L+ + P P P++L + P
Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656
Score = 48.9 bits (115), Expect = 2e-05
Identities = 59/250 (23%), Positives = 84/250 (33%), Gaps = 17/250 (6%)
Query: 249 GRIMTPSVK----VEKIHPKMDGTLLKSAVGPTCPATVSSLVKPGLNCPSIPKPTLPSPG 304
G+ T S K +EK K K PT P ++ P L P P PT P
Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT-PKAETTTKGPALTTPKEPTPTTPKEP 358
Query: 305 QILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
K P P T++ P K +P TK+P +
Sbjct: 359 ASTTPKE-PTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP------APTTTKEPAPTTPKE 411
Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
+ T+ A K E T +K P P P ++P P P+
Sbjct: 412 PAPTTTKEPAPT-TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPTTPKEPAP 469
Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPAT 484
+ P P E P KP P TP P P P + + +P P +P P P T
Sbjct: 470 TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPT--TPKEPAPTT 526
Query: 485 EPASRLSSEE 494
++ +++E
Sbjct: 527 TKSAPTTTKE 536
Score = 46.6 bits (109), Expect = 1e-04
Identities = 119/569 (20%), Positives = 183/569 (32%), Gaps = 69/569 (12%)
Query: 139 CPAHDDFYLVVCNDCN-----QVVKPQAFQSHYERRHSSSSKPPLAVPPTSVFSFFPSLS 193
CP ++ F V N + + P + S KPP V S
Sbjct: 97 CPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIE---SEE 153
Query: 194 KSKGGSASGSNRSSSGGVLSASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMT 253
++ S S + SSS S+SSS+ + +KS K R + + + + T
Sbjct: 154 ITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT 213
Query: 254 PSVKV-EKIHPKMDGTLLKSAVGPTCPAT---VSSLVKPGLNCPSIPKPTLPSPGQILNG 309
P V ++ +D K T VS+ K P P+P+LP
Sbjct: 214 PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 273
Query: 310 KGLPA--PPTLEKKPEDNSNNRKFLN---KRLSEREFDPDIHCGVIDLDTKKPCTRSLTC 364
L T+E K +N + + K S +E DL T
Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 333
Query: 365 KTHSLTQRRAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQE 424
K + T+ A+ ++ E + T KE P P PAP T
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTT-PKEPTPTTIKSAPTTP---KEPAPTTTKSA 389
Query: 425 PHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGC--PA-QQGGSAPIDP-PPVHESPHPP 480
P P E P +P P TP P P PA SAP P P +P P
Sbjct: 390 P------TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 443
Query: 481 LPAT--EPASRLSSEEGEGDDKEES-VEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFD 537
P T EPA E KE + K + P P +
Sbjct: 444 APTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTA----------------- 486
Query: 538 SRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAA 597
+K + P P +P +T+ P T P + +A
Sbjct: 487 -------------PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT--TPKEPAPTTTKSAP 531
Query: 598 TVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPS 657
T + P ++T +P + P+ TT +PA + +P + + ++ P+ +
Sbjct: 532 TTTKEPA-PTTTKSAPTTPKEPSPTTT--KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588
Query: 658 GLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
P++ P K PKE++
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Score = 41.6 bits (96), Expect = 0.003
Identities = 105/516 (20%), Positives = 171/516 (33%), Gaps = 56/516 (10%)
Query: 213 SASSSSSKLLKSPKEKLQLRGNTRPMHPIQQSRVPHGRIMTPSVKVEKIHPKMDGTLLKS 272
+A ++ KL + EKL +P + P T + P+
Sbjct: 616 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP-----TTPEEPTPTTPEEPAPTTPK 670
Query: 273 AVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRK 330
A P P + +P P P PT P KG AP TL K+P +
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT-APTTL-KEPAPTTP--- 725
Query: 331 FLNKRLSEREFDPDIHCGVIDLDTKKPCTRSLTC-KTHSLTQRRAVQGRRKRFDVLLAEH 389
K+ + +E P TK+P S TC K T + K +
Sbjct: 726 ---KKPAPKELAPTT--------TKEPT--STTCDKPAPTTPKGTAPTTPKEPAPTTPKE 772
Query: 390 KNKTREKELIRHPDSQQPPQPLRDPHPAP----PRTSQEP----HQNPHGVIPSESKPFV 441
T K P + + P P PAP P T++ P P P E+ P
Sbjct: 773 PAPTTPKGTA--PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830
Query: 442 ASKPKPHTPSLPRP----PGCPAQQGGSAPI---DPPPVHESPHPPLPATEPASRLSSEE 494
+P P TP P P P S P +P +H+SP P E ++ + +
Sbjct: 831 PKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP--ELSAEPTPKA 888
Query: 495 GEGDDKEESVEKLDCHYSGHHPQPASFCTFGSRQIGRGYYVFDSRWN---RLRCALNLMV 551
E KE V + +P T + R ++
Sbjct: 889 LENSPKEPGVPTTKTPAA---TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 945
Query: 552 EKHLNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCI 611
EK +++ V STT+ +T T T V+ +T +
Sbjct: 946 EKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 1005
Query: 612 SPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSR---QVSSSSSSPSTPSGLSSVPS-SPM 667
P ++ + TT Q P + + + +V ++P+ S++P +P
Sbjct: 1006 KPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPT 1065
Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
SR + + + + RP ++ + N S +GG+
Sbjct: 1066 SRIAEAMLQT-TTRPNQTPNSKLVEVNPKSEDAGGA 1100
Score = 40.8 bits (94), Expect = 0.006
Identities = 108/526 (20%), Positives = 153/526 (29%), Gaps = 89/526 (16%)
Query: 268 TLLKSAVGPTCPATVSSLV--KPGLNCPSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDN 325
T KSA PT P + KP P P PT P K PAP T E P
Sbjct: 423 TTTKSA--PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTTP 479
Query: 326 SNNRKFLNKR---LSEREFDPDIHCGVIDLDTKKPCTRS------LTCKTHSLTQRRAVQ 376
K+ + +E P TK+P + T K+ T +
Sbjct: 480 KEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539
Query: 377 GRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSE 436
K E T ++ P P P + P P P+ P P E
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP-KKPAPTTPK-------EPAPTTPKE 591
Query: 437 SKPFVASKPKPHTPSLPRP---------------PGCPAQQGGSAPIDPPPVHE------ 475
P KP P TP P P P P + + P P P
Sbjct: 592 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 651
Query: 476 SPHPPLPAT--EPASRLSSEEGEGDDKEES--VEKLDCHYSGHHPQPASFC-TFGSRQIG 530
+P P P T EPA KE + K + P P + T + G
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711
Query: 531 RGYYVFDSRWNRLRCALNLMVEKHLNAQLWKKIPPVPSTTSPISTRIPHRTNS---VPTS 587
K KK P P +P +T+ P T PT+
Sbjct: 712 TAPTTL----------------KEPAPTTPKK--PAPKELAPTTTKEPTSTTCDKPAPTT 753
Query: 588 QCGVSYLA----AATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
G + A T P + +P + PA T P + P +
Sbjct: 754 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE---LAPTTTKGP 810
Query: 644 RQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGS 703
+S +P+TP + P++P P K P+ ++ +++
Sbjct: 811 TSTTSDKPAPTTPK--ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT----- 863
Query: 704 GKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPST 749
P +H S S+ S+ +N G P T
Sbjct: 864 ------KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 903
Score = 33.1 bits (74), Expect = 1.2
Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 3/110 (2%)
Query: 649 SSSSPSTPSGLSSVPSSPMSRKPQ---KLKSSKSLRPKESSGNSTNCQNASSSTSGGSGK 705
SS PSG S S R P+ K K+ K + +E + + +N SS+S S
Sbjct: 115 SSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSS 174
Query: 706 KRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHS 755
+ +S+++ ++ +KN P P V + S
Sbjct: 175 SSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGS 224
Score = 32.3 bits (72), Expect = 2.0
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 7/114 (6%)
Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSV----PAHGTTLNAQPAASGAMD 636
T + TS G +A + S S+ ++P SK + P TT PA + +
Sbjct: 291 TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG-PALTTPKE 349
Query: 637 PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
P + S++ P TP+ + S P++P P KS+ + PKE + +T
Sbjct: 350 PTPTTPKEPASTTPKEP-TPTTIKSAPTTPKEPAPTTTKSAPT-TPKEPAPTTT 401
Score = 32.0 bits (71), Expect = 2.6
Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 9/151 (5%)
Query: 564 PPVPSTTSPISTR--IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
P P +P +T+ P T S PT+ T+P + T + + P
Sbjct: 406 PTTPKEPAPTTTKEPAPTTTKSAPTTP-------KEPAPTTPKKPAPTTPKEPAPTTPKE 458
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
T + A +P + ++ P+ + P++P P K
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT 518
Query: 682 PKESSGNSTNCQNASSSTSGGSGKKRKNSSP 712
PKE + +T ++ + K ++P
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 51.2 bits (121), Expect = 4e-06
Identities = 121/549 (22%), Positives = 175/549 (31%), Gaps = 95/549 (17%)
Query: 32 QQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGG---PGAASTSAAAMATVGE-----RR- 82
Q Q PPPP P PPPPP GG P ST + RR
Sbjct: 1031 QSGPHQAAPPPPPP-----PPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRD 1085
Query: 83 -PLPSPEVMLGQSWNLWVEASKLPGKDGTELDESFKEFGKNREVMGLCREDMPI-----F 136
P +P+ + Q + + K L+ + +++ CR +
Sbjct: 1086 PPFQTPKKLYAQEYEFEADEDKADVPADIRLNPR-----RLPDLVSSCRSRPALSPLGDI 1140
Query: 137 GFCPAHDDFYLVVCNDCNQVVKP-QAFQSHYERRHSSSSKPPLAVP----PTSVFSFFPS 191
FCP + + KP +A + R PL VP P S +
Sbjct: 1141 DFCPPNPG----PDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDG 1196
Query: 192 LSKSKG-GSASGSNRSSSGGVLSASSSSSKL-LKSPKEKLQLRGNTRPM-----HPIQQS 244
K +G G G +GG K+ L PK L ++ H S
Sbjct: 1197 AKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDS 1256
Query: 245 RVPHGRIMTPSVKVEKIHPKMDGTLLKSAV-----GPTCPATVSSLVKPGLNCPSIPKPT 299
+ +I +VE+ P+M + S + G P + + P L+ P P+
Sbjct: 1257 SLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPS 1316
Query: 300 LPSPG----------------------------QILNGKGLPAPPTLEKKPEDNSNNRKF 331
+P+ G G GL P ++ E+ N +
Sbjct: 1317 VPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLET 1376
Query: 332 LNKRLSE--------REFDPDIHCGVIDLDTKKPCTRSLTCKTHS--LTQRRAVQGRRKR 381
L S+ R+ I + LD T L AV G
Sbjct: 1377 LPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPP- 1435
Query: 382 FDVLLAEHKNKTREKELIRH-PDSQQPPQPLRDPHPAPPRTSQEPH--QNPHGVIPSESK 438
L + + N T E L+ P PP P P P PP +P P V P+ S
Sbjct: 1436 LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSS 1495
Query: 439 PFVASKPKPHTPSLPRPPGCPAQQGG--SAPIDPPPVHESPHPPLPATEPASRLSSEE-- 494
P P P P++P PP P +AP + P P LP T P +E
Sbjct: 1496 PPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETA 1555
Query: 495 ---GEGDDK 500
GE D++
Sbjct: 1556 AVCGETDEE 1564
Score = 38.5 bits (88), Expect = 0.028
Identities = 31/104 (29%), Positives = 39/104 (37%), Gaps = 23/104 (22%)
Query: 402 PDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQ 461
P+ + P+ P P PP +P+G P AS P TP L P P +
Sbjct: 968 PEDEGDPKAGAGPPPGPPA------YDPYGPYC----PGRASGAGPETPGLGLDPNKPPE 1017
Query: 462 -------------QGGSAPIDPPPVHESPHPPLPATEPASRLSS 492
Q G PPP P PP PA+EP L+S
Sbjct: 1018 LPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTS 1061
Score = 35.4 bits (80), Expect = 0.24
Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 22/91 (24%)
Query: 411 LRDPHPAPPRTSQEPHQNPHGVI---PSESKPFVASKPKP--------HTPSLPRPPGC- 458
L+ P PP T+Q PHG++ P V P P H PS P P
Sbjct: 760 LQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPS-PSPSASK 818
Query: 459 -------PAQQGGSAPIDPPPVHESPHPPLP 482
PA + G+ PPP P PP+P
Sbjct: 819 VGVHLLEPATRDGAP--QPPPPPPPPPPPMP 847
Score = 33.1 bits (74), Expect = 1.2
Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 9/94 (9%)
Query: 406 QPPQPLRDPHPAPPRTSQ-EPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGG 464
QPP P P P PP Q E H HG+ P+ P + + SL P G
Sbjct: 834 QPPPP--PPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPE-----ESLDPPGAMQELLGA 886
Query: 465 SAPIDPPPVHESPHPP-LPATEPASRLSSEEGEG 497
P+ P P PP +PA S +G
Sbjct: 887 LEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920
Score = 32.0 bits (71), Expect = 2.6
Identities = 31/121 (25%), Positives = 43/121 (35%), Gaps = 16/121 (13%)
Query: 376 QGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPHGVIPS 435
+ R +R V E+ NK + +PP P+R R+ Q +NP S
Sbjct: 1639 KNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVR-------RSGQA--KNPVSAGGS 1689
Query: 436 ESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEG 495
S P P P+ P P P + P + P P PP P R +E
Sbjct: 1690 -------SAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEK 1742
Query: 496 E 496
E
Sbjct: 1743 E 1743
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 50.4 bits (119), Expect = 7e-06
Identities = 54/195 (27%), Positives = 70/195 (35%), Gaps = 18/195 (9%)
Query: 293 PSIPKPTLPSPGQILNGKGLPAPPTLEKKPEDNSNNRKFLNKRLS-EREFDPDIHCGVID 351
PSIP P + S + K L E + N N +K K S E E + CG
Sbjct: 1848 PSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKSGEGENTDKLECGTCG 1907
Query: 352 LDTKKPCTRSLTCKTHSLTQRRAVQGRRKRFDVL--LAEHKNKTREKELIRHPDSQQPPQ 409
K + L K+H + V G+ + L A + +K P S + P
Sbjct: 1908 ----KLFSNVLILKSH----QEHVHGQFFPYAALEKFARQYREAYDKLYPISPSSPETPP 1959
Query: 410 PLRDPHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPID 469
P P P PP Q P + + S P A P P P P PP P P
Sbjct: 1960 PPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPP-------PPP 2012
Query: 470 PPPVHESPHPPLPAT 484
PPP P LP +
Sbjct: 2013 PPPPSAPPQVQLPVS 2027
Score = 38.1 bits (87), Expect = 0.037
Identities = 16/32 (50%), Positives = 21/32 (65%)
Query: 30 QQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPE 61
QQQ QQ Q P QPQ+QQ PPPP++ + +
Sbjct: 1752 QQQAQQYQATQPQLQPQKQQQQPPPPQQQQQQ 1783
Score = 36.2 bits (82), Expect = 0.14
Identities = 16/24 (66%), Positives = 18/24 (75%)
Query: 26 AAARQQQQQQQQQQPPPPQPQRQQ 49
A Q Q Q+QQQQPPPPQ Q+QQ
Sbjct: 1760 ATQPQLQPQKQQQQPPPPQQQQQQ 1783
Score = 33.1 bits (74), Expect = 1.2
Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 5/84 (5%)
Query: 7 DDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQ---RQQHPPPPPRRTRPEDG 63
D + AA++ G + + + ++ P P P +Q P PP + T+P
Sbjct: 2326 DAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKP--A 2383
Query: 64 GPGAASTSAAAMATVGERRPLPSP 87
P A+++S A+ + +P P P
Sbjct: 2384 LPLASTSSDPPQASTAQPQPQPQP 2407
Score = 31.6 bits (70), Expect = 3.4
Identities = 14/25 (56%), Positives = 17/25 (68%)
Query: 25 AAAARQQQQQQQQQQPPPPQPQRQQ 49
A + Q Q+QQQQ PPP Q Q+QQ
Sbjct: 1760 ATQPQLQPQKQQQQPPPPQQQQQQQ 1784
Score = 31.2 bits (69), Expect = 4.5
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 15/75 (20%)
Query: 414 PHPAPPRTSQEPHQNPHGVIPSESKPFVASKPKPHTPSLPRPPGCPAQQGGSAPIDPPPV 473
P P P +TS +P + A KPK PS P PA S DPP
Sbjct: 2350 PKPEPEKTSPKPE-------------YPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQA 2396
Query: 474 HES-PHP-PLPATEP 486
+ P P P P +P
Sbjct: 2397 STAQPQPQPQPPKQP 2411
Score = 30.8 bits (68), Expect = 5.9
Identities = 17/43 (39%), Positives = 21/43 (48%)
Query: 459 PAQQGGSAPIDPPPVHESPHPPLPATEPASRLSSEEGEGDDKE 501
PA SAP P P PP P P+S LS ++ E +KE
Sbjct: 3101 PALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKE 3143
Score = 30.0 bits (66), Expect = 10.0
Identities = 15/26 (57%), Positives = 17/26 (65%), Gaps = 1/26 (3%)
Query: 29 RQQQQQQQQQQPP-PPQPQRQQHPPP 53
+QQ QQ Q QP PQ Q+QQ PPP
Sbjct: 1752 QQQAQQYQATQPQLQPQKQQQQPPPP 1777
Score = 30.0 bits (66), Expect = 10.0
Identities = 11/22 (50%), Positives = 12/22 (54%)
Query: 40 PPPPQPQRQQHPPPPPRRTRPE 61
PPPP P PPPPP P+
Sbjct: 2000 PPPPPPPPPPPPPPPPPSAPPQ 2021
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 49.7 bits (117), Expect = 1e-05
Identities = 56/228 (24%), Positives = 92/228 (40%), Gaps = 4/228 (1%)
Query: 626 NAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKES 685
N+ + S + + S S S SS S + + S SS S SS S +S
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 686 SGNS--TNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSG 743
S +S + N+S S+ + NSS S SS S SS+SS S S + ++S
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 744 PPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLS 803
S+ +S S + +N++++ N S + + NSSDS+ S
Sbjct: 840 DSSDSSDSSDGSDSDS--SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 804 LGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSS 851
S++ +S S S + + + + S SS ++ SS
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945
Score = 49.7 bits (117), Expect = 1e-05
Identities = 69/283 (24%), Positives = 107/283 (37%), Gaps = 12/283 (4%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
S+ S S+ +NS +S S ++ + ++S SS + S + + +
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
+S + D S S +SS SS S+ S SS S + S
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868
Query: 688 NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYP 747
+S++ N+S S+ + NSS S+SS S SS SS+S +S + + S
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Query: 748 STVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPF 807
S+ S+ S N + ++ D S + S S S NSSDS+ S
Sbjct: 929 SSDNSNSSDSSNSSDSSDSS-----DSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS---- 979
Query: 808 IHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSS 850
SN + S S D S SS +NSS
Sbjct: 980 ---SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Score = 49.3 bits (116), Expect = 2e-05
Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 14/244 (5%)
Query: 607 SSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSP 666
SS + S ++ + + +S + D S S S SS+S + +S SS
Sbjct: 737 SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796
Query: 667 MSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSS 726
S SS S +SS + ++ N+S S++ NSS SS SS SS
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSS--NSSDSSNSSDSSDSSNSS-----DSSDSSDSSD 849
Query: 727 SSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAE 786
S S S R + S S ++S + +N+++ + D S S +
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Query: 787 SIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSI 846
+ S NSSDS+ S SN ++ S+S D S +SS
Sbjct: 910 NSSDSSDSSNSSDSSES-------SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962
Query: 847 NNSS 850
+NSS
Sbjct: 963 SNSS 966
Score = 46.6 bits (109), Expect = 1e-04
Identities = 56/221 (25%), Positives = 82/221 (37%), Gaps = 11/221 (4%)
Query: 631 ASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNST 690
+S + D S S S SS S S+ S SS S S S S +S+
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 691 NCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTV 750
N ++S+S+ NSS SS SS S+ SS+ S S N ++
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSD----SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSS 912
Query: 751 TSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQ 810
SS S + + +N+ + + S + S NSSDS+ +
Sbjct: 913 DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS-------NS 965
Query: 811 SNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSS 851
S+ NS S S++ S SS S N+S S
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/248 (25%), Positives = 92/248 (37%), Gaps = 3/248 (1%)
Query: 607 SSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSP 666
SS S +S S + + + +S + D S S S SS S S S S S
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636
Query: 667 MSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSS-SS 725
S+ +S S +S+N N+S S+ +SS S SS SS SS
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 726 SSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNC--VTNKANAVNVRHDQSGRGPPTGS 783
+SS S +S + S S SS S N ++ +N+ + S
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 784 PAESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSS 843
+ S +SSDS+ S + NS S S++ S SS
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 844 SSINNSSS 851
S +++SS
Sbjct: 817 DSDSSNSS 824
Score = 45.4 bits (106), Expect = 2e-04
Identities = 66/285 (23%), Positives = 110/285 (38%), Gaps = 2/285 (0%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
S+ S S+ +NS +S S ++ + +S SS S +S + + N+
Sbjct: 861 SSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNS 920
Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
++ + S S +SS SS S+ S SS S+ S + S
Sbjct: 921 SDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980
Query: 688 NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSS-SSHSMESFRKNCVAHSGPPY 746
NS++ ++S S+ NSS S SS SS+SS SS+S +S + + S
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 747 PSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGP 806
S+ SS S + +N +++ + S + S +SS+S+ S
Sbjct: 1041 DSS-DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 807 FIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSS 851
+ +S S S + S SS S N+S S
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Score = 40.4 bits (93), Expect = 0.007
Identities = 47/176 (26%), Positives = 71/176 (40%), Gaps = 6/176 (3%)
Query: 676 SSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFR 735
S+ +S+GN N + + + G GK + S S+SS SS SS S S +S
Sbjct: 517 STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS 576
Query: 736 KNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMV 795
+ S + S S N ++ ++ + D S + S ++S K S
Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSN--SSDSSDSSDSSDSSDSSDSSDSKSDSSKSES--- 631
Query: 796 NSSDSTLSLGPFIHQSNELPVNSHGS-FSHSHTPLDKLIGKKRKCSPSSSSINNSS 850
+SSDS S++ NS S S+S D S SSS +NSS
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687
Score = 39.3 bits (90), Expect = 0.016
Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 4/161 (2%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
S+ S S+ +NS +S S ++ + +S SS + S ++ + +
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 628 QPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSG 687
+S + D S S S SS S + + S SS S SS S +SS
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 688 NSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
+S + ++ SS S S NSS S SS SS SS S
Sbjct: 1123 SSDSSDSSDSSDSSDSS----NSSDSSDSSESSDSSDSSDS 1159
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/257 (22%), Positives = 100/257 (38%), Gaps = 28/257 (10%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
+TT+ + + ++S TS S + AT T+ ++ +P + +P TT
Sbjct: 3925 TTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 3984
Query: 628 QPAA-SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS-RKPQKLKSSKSLRPKES 685
PAA S + P ++ + ++ +T G S PSSP + R +S +L
Sbjct: 3985 TPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 4044
Query: 686 SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
+ ST + ++T+G + HS+ + SS SS + ES PP
Sbjct: 4045 TEPSTGTSHTPAATTGTTQ-----------HSTPALSSPHPSSRTTES----------PP 4083
Query: 746 YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLG 805
P T T H+ + T A R PT +P +V+ + +
Sbjct: 4084 SPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPI-----TTVVTTGCEPQCAWS 4138
Query: 806 PFIHQSNELPVNSHGSF 822
++ S +P S G F
Sbjct: 4139 EWLDYSYPMPGPSGGDF 4155
Score = 48.5 bits (114), Expect = 3e-05
Identities = 59/278 (21%), Positives = 104/278 (37%), Gaps = 31/278 (11%)
Query: 564 PPV-PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKS----- 617
PPV STT+ +TR + P+S G ++ A +T+ + + + +P+S +
Sbjct: 3333 PPVWISTTTTPTTR---GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGT 3389
Query: 618 ----------VPAHGTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM 667
+ A G+T N P + +++SS TPS +P
Sbjct: 3390 PPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 3449
Query: 668 SRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSS 727
+SL P T +A+S G + + P V S + ++++S++
Sbjct: 3450 VPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTT----HITEPSTVTSHTPAATTSTT 3505
Query: 728 SHS---MESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSP 784
HS + S + PP P T T H+ G + T A R PT +P
Sbjct: 3506 QHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAP 3565
Query: 785 AESIKRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSF 822
+V+ + + ++ S +P S G F
Sbjct: 3566 I-----TTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDF 3598
Score = 47.8 bits (112), Expect = 5e-05
Identities = 53/226 (23%), Positives = 89/226 (39%), Gaps = 23/226 (10%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
+TT+ + + ++S TS S AT T+ ++ +P + +P TT
Sbjct: 2668 TTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 2727
Query: 628 QPAA-SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS-RKPQKLKSSKSLRPKES 685
PAA S + P ++ + ++ +T G S PSSP + R +S +L
Sbjct: 2728 TPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 2787
Query: 686 SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
+ ST + ++T+G + HS+ + SS SS + ES PP
Sbjct: 2788 TEPSTGTSHTPAATTGTTQ-----------HSTPALSSPHPSSRTTES----------PP 2826
Query: 746 YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRM 791
P T T H+ + T A R PT +P ++ M
Sbjct: 2827 SPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2872
Score = 45.4 bits (106), Expect = 2e-04
Identities = 53/226 (23%), Positives = 88/226 (38%), Gaps = 23/226 (10%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNA 627
+TT+ + + ++S TS S AT T+ ++ +P + +P TT
Sbjct: 2111 TTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTAT 2170
Query: 628 QPAA-SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMS-RKPQKLKSSKSLRPKES 685
PAA S + P ++ + ++ +T G S PSSP + R +S L
Sbjct: 2171 TPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI 2230
Query: 686 SGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPP 745
+ ST + ++T+G + HS+ + SS SS + ES PP
Sbjct: 2231 TEPSTVTSHTLAATTGTTQ-----------HSTPALSSPHPSSRTTES----------PP 2269
Query: 746 YPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESIKRM 791
P T T H+ + T A R PT +P ++ M
Sbjct: 2270 SPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTM 2315
Score = 39.3 bits (90), Expect = 0.016
Identities = 71/324 (21%), Positives = 124/324 (38%), Gaps = 37/324 (11%)
Query: 567 PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISP---NSKSVPAHGT 623
P TT ++ T +VPT + AT T V S+T +P +SK+ P+
Sbjct: 4447 PGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHV--STTATTPTVTSSKATPSSSP 4504
Query: 624 -TLNAQPAA-SGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRK-----PQKLKS 676
T A PA S A P + + SSS + T ++ P++ MS P+ + +
Sbjct: 4505 GTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHT 4564
Query: 677 SKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRK 736
S L ++ +T SST G + + ++ +++ SSS ++
Sbjct: 4565 STVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIST 4624
Query: 737 NCVAHSGPPYPS--TVTSS------HSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESI 788
+ P S TVT S H+ + T A S +G+P S+
Sbjct: 4625 TTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPP-SL 4683
Query: 789 KRMSVMVNSSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINN 848
+ + ++ ST + P ++ G+ TP+ ++ ++SS
Sbjct: 4684 TTTATTITATGSTTN-----------PSSTPGT-----TPITPVLTSTATTPAATSSKAT 4727
Query: 849 SSSKPTKVAKVPAVNNVHMKHTGT 872
SSS P +P + + K T T
Sbjct: 4728 SSSSPRTATTLPVLTSTATKSTAT 4751
Score = 35.0 bits (79), Expect = 0.31
Identities = 68/342 (19%), Positives = 123/342 (35%), Gaps = 32/342 (9%)
Query: 567 PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSS----TCISPNSKSVPAHG 622
P TT ++ T +VPT + AT T VL S+ T IS + + G
Sbjct: 3161 PGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPG 3220
Query: 623 TTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM-----SRKPQKLKSS 677
T S A P + + SSS + T ++ P++ M S P+ + +S
Sbjct: 3221 TATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTS 3280
Query: 678 KSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSS--------SSH 729
L ++ +T SST G + + ++ +++ SSS + S+
Sbjct: 3281 TVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTT 3340
Query: 730 SMESFRKNCVAHSG-PPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTGSPAESI 788
+ + R + V S P T T + T + SG P + A +I
Sbjct: 3341 TTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTI 3400
Query: 789 KRMSVMVN--SSDSTLSLGPFIHQSNELPVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSI 846
N S+ T + P + + P + S + TP L P++++
Sbjct: 3401 TATGSTTNPSSTPGTTPIPPVLTTTATTP----AATSSTVTPSSALGTTHTPPVPNTTAT 3456
Query: 847 NNSSSKPTKVAKVPAVNNVHMKHTGTIPGAQGLMNSSLLHQP 888
+ S P ++ H T G++ ++ + +P
Sbjct: 3457 THGRSLPP--------SSPHTVRTAWTSATSGILGTTHITEP 3490
Score = 35.0 bits (79), Expect = 0.31
Identities = 57/267 (21%), Positives = 103/267 (38%), Gaps = 49/267 (18%)
Query: 564 PPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623
PP TSP +T P T+S TS + T +T PVL S+ S + P +
Sbjct: 4280 PPPKVLTSPATT--PTATSSKATSSS-----SPRTATTLPVLTSTATKSTATSVTPIPSS 4332
Query: 624 TLNAQ-PAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRP 682
TL PV +M + SS+ + T + L++ ++ + +S + P
Sbjct: 4333 TLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRA-------TSSTSTP 4385
Query: 683 KESSGNS---TNCQNASSSTSGGSGKKRKNSSP----LLVHSSSSSSSSSSSSHSMESFR 735
+ G + T A+++T+ +S+P +L ++++++++S+
Sbjct: 4386 SSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTG------- 4438
Query: 736 KNCVAHSGPPYPSTVTSSHSIGLNCV-TNKANAVNVRHDQSGRGPPTGSPAESIKRMSVM 794
ST T S + G + T + V PTGS A + +
Sbjct: 4439 ------------STATPSSTPGTTWILTEPSTTATVT-------VPTGSTATASSTQATA 4479
Query: 795 VNSSDSTLSLGPFIHQSNELPVNSHGS 821
ST + P + S P +S G+
Sbjct: 4480 GTPHVSTTATTPTVTSSKATPSSSPGT 4506
Score = 35.0 bits (79), Expect = 0.31
Identities = 36/183 (19%), Positives = 80/183 (43%), Gaps = 13/183 (7%)
Query: 555 LNAQLWKKIPPVPSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPN 614
L +W P+TT+P ++ +S+P G ++ A +T+ + + + +P+
Sbjct: 4616 LTPPVWISTTTTPTTTTPTTSGSTVTPSSIP----GTTHTARVLTTTTTTVATGSMATPS 4671
Query: 615 SK-----SVPAHGTTLNAQPAASGAMDPVCSMQSRQVSS-SSSSPSTPSGLSSVPSSPMS 668
S + P+ TT A +P + + ++ +S+ +TP+ SS +S S
Sbjct: 4672 SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATS--S 4729
Query: 669 RKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGK-KRKNSSPLLVHSSSSSSSSSSS 727
P+ + L + +T+ SST + + ++P+ S+ +SS+ +
Sbjct: 4730 SSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPET 4789
Query: 728 SHS 730
+H+
Sbjct: 4790 THT 4792
Score = 32.3 bits (72), Expect = 2.0
Identities = 28/149 (18%), Positives = 70/149 (46%), Gaps = 3/149 (2%)
Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT-TLNAQPAASGAMDPVC 639
T + T+ G + ++T T+ +L + + + +VP T T ++ A +G
Sbjct: 4429 TTATTTASTGSTATPSSTPGTTWILTEPSTTA--TVTVPTGSTATASSTQATAGTPHVST 4486
Query: 640 SMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSST 699
+ + V+SS ++PS+ G ++ + S +S + P S G + + +++
Sbjct: 4487 TATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 4546
Query: 700 SGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
+ +S+P VH+S+ +++++++
Sbjct: 4547 TATMSTATPSSTPETVHTSTVLTATATTT 4575
Score = 31.2 bits (69), Expect = 4.5
Identities = 33/175 (18%), Positives = 76/175 (43%), Gaps = 15/175 (8%)
Query: 567 PSTTSPISTRIPHRT------------NSVPTSQCGVSYLAAATVSTSPVLLSSTCISPN 614
PST + ST +P T + T G + ++T T+ +L + +
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTA-- 2475
Query: 615 SKSVPAHGT-TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQK 673
+ +VP T T ++ A +G + + V+SS ++P + G ++ + S
Sbjct: 2476 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 2535
Query: 674 LKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
+S + P S G + + +++ + +S+P VH+S+ +++++++
Sbjct: 2536 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTT 2590
Score = 30.8 bits (68), Expect = 5.9
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 21/164 (12%)
Query: 567 PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLN 626
PST + ST + P+S G +++ T P ++T S S + P +TL
Sbjct: 1889 PSTPATSST-------ATPSSTPGTTWIL-----TKPTTTATTTASTGSTATPT--STLR 1934
Query: 627 AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESS 686
P + + V+SS ++PS+ G ++ + P R ++ S+ P SS
Sbjct: 1935 TAPPPKVL---TTTATTPTVTSSKATPSSSPGTAT--ALPALRSTATTPTATSVTPIPSS 1989
Query: 687 GNSTNCQNASSST--SGGSGKKRKNSSPLLVHSSSSSSSSSSSS 728
T S +T + +S+P H+S+ +++++++
Sbjct: 1990 SLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTT 2033
Score = 30.4 bits (67), Expect = 7.7
Identities = 33/177 (18%), Positives = 76/177 (42%), Gaps = 9/177 (5%)
Query: 564 PPVPSTTSPISTR------IPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKS 617
P ST +P ST T + T G + ++T T+ +L + + + +
Sbjct: 3678 PATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTA--TVT 3735
Query: 618 VPAHGT-TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKS 676
VP T T ++ A +G + + V+SS ++P + G ++ + S +
Sbjct: 3736 VPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTAT 3795
Query: 677 SKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES 733
S + P S G + + +++ + +S+P H+S+ +++++++ + S
Sbjct: 3796 SFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 3852
Score = 30.0 bits (66), Expect = 10.0
Identities = 30/155 (19%), Positives = 73/155 (47%), Gaps = 4/155 (2%)
Query: 581 TNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT-TLNAQPAASGAMDPVC 639
T + T+ G + ++T T+ +L + + + +VP T T ++ A +G + +
Sbjct: 3143 TAATTTAATGPTATPSSTPGTTWILTEPSTTA--TVTVPTGSTATASSTRATAGTLKVLT 3200
Query: 640 SMQSRQ-VSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSS 698
S + V SS ++PS+ G ++ + S +S + P S G + + +++
Sbjct: 3201 STATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTT 3260
Query: 699 TSGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMES 733
+ +S+P VH+S+ +++++++ + S
Sbjct: 3261 PTATMSTATPSSTPETVHTSTVLTTTTTTTRATGS 3295
Score = 30.0 bits (66), Expect = 10.0
Identities = 41/162 (25%), Positives = 61/162 (37%), Gaps = 12/162 (7%)
Query: 653 PSTPSGLSS-VPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSS 711
PSTP+ S+ +PSS P L ++ ST SST G + + +S
Sbjct: 4232 PSTPATSSTAMPSST----PGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTS 4287
Query: 712 PLLVHSSSSSSSSSSSSHS-------MESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNK 764
P +++SS ++SSSS + S A S P PS+ + T
Sbjct: 4288 PATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTP 4347
Query: 765 ANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGP 806
++ H S S + K + SS ST S P
Sbjct: 4348 VATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTP 4389
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 49.7 bits (117), Expect = 1e-05
Identities = 29/74 (39%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 15 RAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSAAA 74
RA A A A +Q+ QQ QPPPPQPQ PPPPP++ P P AA + A
Sbjct: 2481 RAERIAKEKKALADQQKAQQPAVAQPPPPQPQ----PPPPPQQPPPPLPQPQAAGSQPPA 2536
Query: 75 MATVGERRPLPSPE 88
+ +P P P+
Sbjct: 2537 GPPAVQPQPQPQPQ 2550
Score = 41.6 bits (96), Expect = 0.003
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 9/91 (9%)
Query: 386 LAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQNPH--GVIPSESKPFVAS 443
+A+ K +++ + P QPP P P P PP+ P P G P P V
Sbjct: 2485 IAKEKKALADQQKAQQPAVAQPPPPQPQP-PPPPQQPPPPLPQPQAAGSQPPAGPPAVQP 2543
Query: 444 KPKPHTPSLPRPPGCPAQ------QGGSAPI 468
+P+P + P+P PA+ GGSA +
Sbjct: 2544 QPQPQPQTQPQPVQAPAKAQPAITTGGSAAV 2574
Score = 37.0 bits (84), Expect = 0.082
Identities = 33/138 (23%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 563 IPPVPSTTSPISTRIPHRTN-SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAH 621
IP PS+ PI P + VPT G + A+ +S+ P +++ST + + PA
Sbjct: 602 IPAPPSSQLPIPPSQPAQLALHVPTP--GKVQVQASQLSSLPQMVASTRLPVD----PAP 655
Query: 622 GTTLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLR 681
+++ ++ PV + SS + PS ++ SP++ + + +S +
Sbjct: 656 PCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTK 715
Query: 682 PKESSGNSTNCQNASSST 699
P+ + N+T+ Q++S T
Sbjct: 716 PQSPAQNATSSQDSSQDT 733
Score = 33.1 bits (74), Expect = 1.2
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 30 QQQQQQQQQQPPPPQPQRQQHPPPPPRRTRPEDGGPGAASTSAAAMATVGERRP 83
+ Q+Q+ Q P PP PQ Q PP P + + + P + + TV RP
Sbjct: 2782 KMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQP--PQQQSPQLTTVTAPRP 2833
Score = 32.3 bits (72), Expect = 2.0
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 2 SERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQPPPPQPQRQ---QHPPPPPRRT 58
+ER A + + + A A Q Q QQPPPP PQ Q PP P
Sbjct: 2482 AERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAV 2541
Query: 59 RPE 61
+P+
Sbjct: 2542 QPQ 2544
Score = 32.0 bits (71), Expect = 2.6
Identities = 15/21 (71%), Positives = 16/21 (76%)
Query: 29 RQQQQQQQQQQPPPPQPQRQQ 49
RQQQQQQQQQQ Q Q+QQ
Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQ 2738
Score = 31.6 bits (70), Expect = 3.4
Identities = 18/51 (35%), Positives = 24/51 (47%), Gaps = 2/51 (3%)
Query: 2 SERAADDVRGEPRRAAAAAGGAAAAAARQQQQQQQQQQP--PPPQPQRQQH 50
S+ +A R +P A++ A A A + Q Q P PPPQPQ H
Sbjct: 1490 SQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSH 1540
Score = 31.6 bits (70), Expect = 3.4
Identities = 35/141 (24%), Positives = 51/141 (36%), Gaps = 35/141 (24%)
Query: 373 RAVQGRRKRFDVLLAEHKNKTREKELIRHPDSQQPPQPLRDPHPAPPRTSQEPHQ-NP-H 430
++ R R + A+ +N T + H D + R P P P P Q NP H
Sbjct: 2399 KSKNNRPLRTSQIYAQDENATHTQLYTSHFDLMKMTAGKRSP-PIKPLLGMNPFQKNPKH 2457
Query: 431 GVIPSES------------------------KPFVASKPKPHTPSLPRPPGCPAQQGGSA 466
+ +ES K +A + K P++ +PP P Q
Sbjct: 2458 ASVLAESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPP--PPQP---- 2511
Query: 467 PIDPPPVHESPHPPLPATEPA 487
PPP + P PPLP + A
Sbjct: 2512 --QPPPPPQQPPPPLPQPQAA 2530
Score = 31.2 bits (69), Expect = 4.5
Identities = 22/55 (40%), Positives = 23/55 (41%), Gaps = 1/55 (1%)
Query: 23 AAAAAARQQQQQQQQQQPPPPQPQRQQHPPPPPRRTR-PEDGGPGAASTSAAAMA 76
A A RQ QQQ PP Q H P P R P G P AA +SA A
Sbjct: 523 AQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFA 577
Score = 31.2 bits (69), Expect = 4.5
Identities = 15/30 (50%), Positives = 19/30 (63%)
Query: 29 RQQQQQQQQQQPPPPQPQRQQHPPPPPRRT 58
+QQQQQQQQQQ Q Q+QQ ++T
Sbjct: 2719 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQT 2748
>gi|22325364 ubiquitin associated protein 2 [Homo sapiens]
Length = 1119
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/243 (25%), Positives = 100/243 (41%), Gaps = 47/243 (19%)
Query: 568 STTSPISTRIPHRTNSVPTSQCGVSYLAAATV------STSPVLLSSTCI---------- 611
S + P++T + T++V S S + + ++ S SPV +SS+
Sbjct: 570 SLSEPLNTSLS-MTSAVQNSTYTTSVITSCSLTSSSLNSASPVAMSSSYDQSSVHNRIPY 628
Query: 612 -SPNSKSVPAHGTTLNAQ-----------PAASGAMDPVCSMQSRQVSSSSSS--PSTPS 657
SP S S A GT +N P +G + S+ S ++S ++ PST
Sbjct: 629 QSPVSSSESAPGTIMNGHGGGRSQQTLDTPKTTGPPSALPSVSSLPSTTSCTALLPSTSQ 688
Query: 658 GLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHS 717
+ SSP+S+ L S +S ++ +S+ +S S S + S
Sbjct: 689 HTGDLTSSPLSQLSSSLSSHQSSLSAHAALSSSTSHTHASVESASSHQSSATFSTAATSV 748
Query: 718 SSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGR 777
SSS+SS +S S SM + C+ + P++ +SS S VT SG+
Sbjct: 749 SSSASSGASLSSSMNTANSLCLGGT----PASASSSSSRAAPLVT------------SGK 792
Query: 778 GPP 780
PP
Sbjct: 793 APP 795
Score = 37.7 bits (86), Expect = 0.048
Identities = 61/286 (21%), Positives = 112/286 (39%), Gaps = 27/286 (9%)
Query: 584 VPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLNAQPAASGAMDPVCSMQS 643
+P G+ + A +++ L++ +P V G +A PA A P QS
Sbjct: 835 LPVDYYGIPFAAPTALASRDGSLAN---NPYPGDVTKFGRGDSASPAP--ATTPAQPQQS 889
Query: 644 RQVSSSSS-----SPSTPSGLSSVPSSPMSRKPQKLKSSKSLRPKESSGNSTNCQNASSS 698
+ + ++ +P+ P G S + P + ++ +S N S+
Sbjct: 890 QSQTHHTAQQPFVNPALPPGYSYTGLPYYTGMPSAFQYGPTMFVPPASAKQHGV-NLSTP 948
Query: 699 T-----SGGSGKKRKNSSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPYPSTVTSS 753
T + G G+ ++ + +++ S ++ S N A SGP +V+SS
Sbjct: 949 TPPFQQASGYGQHGYSTGYDDLTQGTAAGDYSKGGYAGSSQAPNKSAGSGPGKGVSVSSS 1008
Query: 754 HSIGLNCVT----NKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIH 809
+ GL +T NK + + +G PP P+ + + + + + PF+H
Sbjct: 1009 -TTGLPDMTGSVYNKTQTFDKQGFHAGTPPPFSLPSV-LGSTGPLASGAAPGYAPPPFLH 1066
Query: 810 QSNELPVNS--HGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKP 853
LP + H H H P D G ++ PSS + +SKP
Sbjct: 1067 I---LPAHQQPHSQLLHHHLPQDAQSGSGQRSQPSSLQPKSQASKP 1109
Score = 36.6 bits (83), Expect = 0.11
Identities = 42/155 (27%), Positives = 71/155 (45%), Gaps = 9/155 (5%)
Query: 567 PSTTSPISTRIPHRTNSVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGTTLN 626
P TT P S +P +S+P++ + L + + T L+S+ +S S S+ +H ++L+
Sbjct: 658 PKTTGPPSA-LPS-VSSLPSTTSCTALLPSTSQHTGD--LTSSPLSQLSSSLSSHQSSLS 713
Query: 627 AQPAASGAMD----PVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSRKPQKLKSSKSLRP 682
A A S + V S S Q SS++ S + S SS S +S L
Sbjct: 714 AHAALSSSTSHTHASVESASSHQ-SSATFSTAATSVSSSASSGASLSSSMNTANSLCLGG 772
Query: 683 KESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHS 717
+S +S++ + A TSG + P L+H+
Sbjct: 773 TPASASSSSSRAAPLVTSGKAPPNLPQGVPPLLHN 807
Score = 32.7 bits (73), Expect = 1.5
Identities = 53/230 (23%), Positives = 84/230 (36%), Gaps = 45/230 (19%)
Query: 651 SSPSTPSGLSSVPSSPMSRK-PQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKN 709
S PS S S PSS S + P L S P +S + T+ S+ T+
Sbjct: 543 SEPSL-SEFGSAPSSENSNQIPISLYSKSLSEPLNTSLSMTSAVQNSTYTT--------- 592
Query: 710 SSPLLVHSSSSSSSSSSSSHSMESFRKNCVAHSGPPY----------PSTVTSSHSIGLN 759
S + S +SSS +S+S +M S H+ PY P T+ + H G
Sbjct: 593 -SVITSCSLTSSSLNSASPVAMSSSYDQSSVHNRIPYQSPVSSSESAPGTIMNGHGGG-- 649
Query: 760 CVTNKANAVNVRHDQSGRGPPTGSPAESIKRMSVMVNSSDSTLSLGPFIHQSNEL----- 814
R Q+ P T P ++ +S + +++ T L + +L
Sbjct: 650 -----------RSQQTLDTPKTTGPPSALPSVSSLPSTTSCTALLPSTSQHTGDLTSSPL 698
Query: 815 -----PVNSHGSFSHSHTPLDKLIGKKRKCSPSSSSINNSSSKPTKVAKV 859
++SH S +H L S+SS +S++ T V
Sbjct: 699 SQLSSSLSSHQSSLSAHAALSSSTSHTHASVESASSHQSSATFSTAATSV 748
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,457,186
Number of Sequences: 37866
Number of extensions: 2839666
Number of successful extensions: 46440
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 641
Number of HSP's successfully gapped in prelim test: 1389
Number of HSP's that attempted gapping in prelim test: 21662
Number of HSP's gapped (non-prelim): 18395
length of query: 892
length of database: 18,247,518
effective HSP length: 111
effective length of query: 781
effective length of database: 14,044,392
effective search space: 10968670152
effective search space used: 10968670152
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.