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Search of human proteins with 4506267
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506267 parathyroid hormone preproprotein [Homo sapiens]
(115 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506267 parathyroid hormone preproprotein [Homo sapiens] 227 2e-60
gi|39995093 parathyroid hormone-like hormone isoform 1 prepropro... 33 0.049
gi|39995091 parathyroid hormone-like hormone isoform 1 prepropro... 33 0.049
gi|39995089 parathyroid hormone-like hormone isoform 2 prepropro... 33 0.049
gi|4506269 parathyroid hormone-like hormone isoform 2 preproprot... 33 0.049
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 31 0.24
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 31 0.24
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 31 0.24
gi|45446749 kinesin family member 5A [Homo sapiens] 29 0.92
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 29 0.92
gi|239757914 PREDICTED: similar to hCG1818060 [Homo sapiens] 28 1.6
gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens] 28 1.6
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 28 1.6
gi|239746943 PREDICTED: hypothetical protein XP_002343887 [Homo ... 28 2.0
gi|239752425 PREDICTED: hypothetical protein XP_002348263 [Homo ... 27 2.7
gi|213385270 RAS guanyl releasing protein 3 (calcium and DAG-reg... 27 2.7
gi|24762239 RAS guanyl releasing protein 3 (calcium and DAG-regu... 27 2.7
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 27 2.7
gi|16506299 leucine rich repeat containing 42 [Homo sapiens] 27 2.7
gi|5453870 platelet-derived growth factor receptor alpha precurs... 27 3.5
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens] 27 3.5
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens] 27 3.5
gi|66730423 hypothetical protein LOC389384 [Homo sapiens] 27 3.5
gi|4505683 platelet-derived growth factor receptor beta precurso... 27 4.5
gi|163644316 hypothetical protein LOC23255 [Homo sapiens] 27 4.5
gi|189011568 adenomatous polyposis coli [Homo sapiens] 26 5.9
gi|189011566 adenomatous polyposis coli [Homo sapiens] 26 5.9
gi|53759122 adenomatous polyposis coli [Homo sapiens] 26 5.9
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 26 5.9
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 26 5.9
>gi|4506267 parathyroid hormone preproprotein [Homo sapiens]
Length = 115
Score = 227 bits (578), Expect = 2e-60
Identities = 115/115 (100%), Positives = 115/115 (100%)
Query: 1 MIPAKDMAKVMIVMLAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQ 60
MIPAKDMAKVMIVMLAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQ
Sbjct: 1 MIPAKDMAKVMIVMLAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQ 60
Query: 61 DVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVNVLTKAKSQ 115
DVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVNVLTKAKSQ
Sbjct: 61 DVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVNVLTKAKSQ 115
>gi|39995093 parathyroid hormone-like hormone isoform 1
preproprotein [Homo sapiens]
Length = 177
Score = 33.1 bits (74), Expect = 0.049
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 12 IVMLAICFLTKSDGKSVK------KRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVH 63
+ + + + S G+SV+ KR+VSE QL+H+ GK + + R +L + ++H
Sbjct: 11 VAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIH 68
>gi|39995091 parathyroid hormone-like hormone isoform 1
preproprotein [Homo sapiens]
Length = 177
Score = 33.1 bits (74), Expect = 0.049
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 12 IVMLAICFLTKSDGKSVK------KRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVH 63
+ + + + S G+SV+ KR+VSE QL+H+ GK + + R +L + ++H
Sbjct: 11 VAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIH 68
>gi|39995089 parathyroid hormone-like hormone isoform 2
preproprotein [Homo sapiens]
Length = 175
Score = 33.1 bits (74), Expect = 0.049
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 12 IVMLAICFLTKSDGKSVK------KRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVH 63
+ + + + S G+SV+ KR+VSE QL+H+ GK + + R +L + ++H
Sbjct: 11 VAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIH 68
>gi|4506269 parathyroid hormone-like hormone isoform 2
preproprotein [Homo sapiens]
Length = 175
Score = 33.1 bits (74), Expect = 0.049
Identities = 17/58 (29%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 12 IVMLAICFLTKSDGKSVK------KRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVH 63
+ + + + S G+SV+ KR+VSE QL+H+ GK + + R +L + ++H
Sbjct: 11 VAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIH 68
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 30.8 bits (68), Expect = 0.24
Identities = 15/46 (32%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Query: 45 HLNSMERVEWLRKKLQDVHN-FVALGAPLAPRDAGSQRPRKKEDNV 89
++NS ER+ +L++KLQ++ +++L + +A D +R +KK+ V
Sbjct: 1110 NMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREV 1155
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 30.8 bits (68), Expect = 0.24
Identities = 15/46 (32%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Query: 45 HLNSMERVEWLRKKLQDVHN-FVALGAPLAPRDAGSQRPRKKEDNV 89
++NS ER+ +L++KLQ++ +++L + +A D +R +KK+ V
Sbjct: 1125 NMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREV 1170
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 30.8 bits (68), Expect = 0.24
Identities = 15/46 (32%), Positives = 31/46 (67%), Gaps = 1/46 (2%)
Query: 45 HLNSMERVEWLRKKLQDVHN-FVALGAPLAPRDAGSQRPRKKEDNV 89
++NS ER+ +L++KLQ++ +++L + +A D +R +KK+ V
Sbjct: 1179 NMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREV 1224
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 28.9 bits (63), Expect = 0.92
Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 12/76 (15%)
Query: 21 TKSDGKSVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQ 80
+K D K +++ E+Q +HNL K +QDV V A + P D+G
Sbjct: 776 SKQDLKGLEETVARELQTLHNLRKLF------------VQDVTTRVKKSAEMEPEDSGGI 823
Query: 81 RPRKKEDNVLVESHEK 96
+K++ + L + E+
Sbjct: 824 HSQKQKISFLENNLEQ 839
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 28.9 bits (63), Expect = 0.92
Identities = 14/33 (42%), Positives = 24/33 (72%), Gaps = 2/33 (6%)
Query: 85 KEDNVLVESHEKSLGE--ADKADVNVLTKAKSQ 115
KE L E+H+++L + A++ VN+LTKAK++
Sbjct: 997 KEKKALQETHQQTLDDLQAEEDKVNILTKAKTK 1029
>gi|239757914 PREDICTED: similar to hCG1818060 [Homo sapiens]
Length = 99
Score = 28.1 bits (61), Expect = 1.6
Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 10/66 (15%)
Query: 27 SVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFV-------ALGAPLAPRDAGS 79
S+ +SV + L LG H N ++ EWL Q + + + PL P G
Sbjct: 28 SLASKSVLSVLLSRQLGNHRNDVDLTEWLWTLKQAIPGWTWPLPTRHTINPPLPP---GE 84
Query: 80 QRPRKK 85
R KK
Sbjct: 85 DRKSKK 90
>gi|22035679 AT rich interactive domain 4B isoform 2 [Homo sapiens]
Length = 1226
Score = 28.1 bits (61), Expect = 1.6
Identities = 16/55 (29%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 44 KHLNSMERVEWLRKKLQDVH-NFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKS 97
+++ S ER+ L++KLQ++ ++++L + +A D +R +KKE S S
Sbjct: 1139 ENMTSAERITILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERESAATSSSSS 1193
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 28.1 bits (61), Expect = 1.6
Identities = 16/55 (29%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Query: 44 KHLNSMERVEWLRKKLQDVH-NFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKS 97
+++ S ER+ L++KLQ++ ++++L + +A D +R +KKE S S
Sbjct: 1225 ENMTSAERITILQEKLQEIRKHYLSLKSEVASIDRRRKRLKKKERESAATSSSSS 1279
>gi|239746943 PREDICTED: hypothetical protein XP_002343887 [Homo
sapiens]
Length = 99
Score = 27.7 bits (60), Expect = 2.0
Identities = 16/62 (25%), Positives = 25/62 (40%), Gaps = 7/62 (11%)
Query: 27 SVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFV-------ALGAPLAPRDAGS 79
S+ +SV + L LG H N + EWL Q + + + PL P + G
Sbjct: 28 SLASKSVLSVLLSRQLGNHRNDADLTEWLWTLKQAIPGWTWPLPTRHTINPPLPPGEDGK 87
Query: 80 QR 81
+
Sbjct: 88 SK 89
>gi|239752425 PREDICTED: hypothetical protein XP_002348263 [Homo
sapiens]
Length = 99
Score = 27.3 bits (59), Expect = 2.7
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 10/66 (15%)
Query: 27 SVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFV-------ALGAPLAPRDAGS 79
S+ +SV + L LG H N + EWL Q + + + PL P G
Sbjct: 28 SLASKSVLSVLLSRQLGNHRNDADLTEWLWTLKQAIPGWTWPLPTRHTINPPLPP---GE 84
Query: 80 QRPRKK 85
R KK
Sbjct: 85 DRKSKK 90
>gi|213385270 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 1 [Homo sapiens]
Length = 690
Score = 27.3 bits (59), Expect = 2.7
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 32 SVSEIQLMHNLGKHLN-SMERVEWLRKKLQDVH---NFVALGAPLAPRDAGSQRPRKKED 87
++SE+ + N HL +M+ + L L H + L L PR++ SQ
Sbjct: 336 TLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTP 395
Query: 88 NVLVESHEKSLGEADKADVNVLTK 111
N V E +LG K D V+ K
Sbjct: 396 NKPVVPLEWALGVMPKPDPTVINK 419
>gi|24762239 RAS guanyl releasing protein 3 (calcium and
DAG-regulated) isoform 1 [Homo sapiens]
Length = 690
Score = 27.3 bits (59), Expect = 2.7
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 4/84 (4%)
Query: 32 SVSEIQLMHNLGKHLN-SMERVEWLRKKLQDVH---NFVALGAPLAPRDAGSQRPRKKED 87
++SE+ + N HL +M+ + L L H + L L PR++ SQ
Sbjct: 336 TLSELVSLQNASHHLEPNMDLINLLTLSLDLYHTEDDIYKLSLVLEPRNSKSQPTSPTTP 395
Query: 88 NVLVESHEKSLGEADKADVNVLTK 111
N V E +LG K D V+ K
Sbjct: 396 NKPVVPLEWALGVMPKPDPTVINK 419
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 27.3 bits (59), Expect = 2.7
Identities = 14/31 (45%), Positives = 22/31 (70%), Gaps = 2/31 (6%)
Query: 85 KEDNVLVESHEKSLG--EADKADVNVLTKAK 113
KE L E+H+++LG +A++ V+ LTKAK
Sbjct: 1043 KEKKALQEAHQQALGDLQAEEDRVSALTKAK 1073
>gi|16506299 leucine rich repeat containing 42 [Homo sapiens]
Length = 428
Score = 27.3 bits (59), Expect = 2.7
Identities = 16/60 (26%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 30 KRSVSEIQLMHNLGK-HLNSMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKEDN 88
KRS +E L L H+NS E++++ ++K D H V ++ +++ + R E++
Sbjct: 340 KRSRAEAPLKCPLADTHMNSSEKLQFYKEKAPDCHGPVLKHEAISSQESKKSKKRPFEES 399
>gi|5453870 platelet-derived growth factor receptor alpha precursor
[Homo sapiens]
Length = 1089
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/36 (33%), Positives = 23/36 (63%)
Query: 12 IVMLAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLN 47
++ +A+ L + S K+ +SE+++M +LG HLN
Sbjct: 621 VMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLN 656
>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
Length = 373
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 48 SMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVN 107
+ +R + +R K++D+ ++ L R+ R+KED V + LG D D +
Sbjct: 110 AFQRPQLMRLKVKDLRQYLIL------RNIPIDTCREKEDLVDLVLCHHGLGSEDDMDTS 163
Query: 108 VLTKAKSQ 115
L ++SQ
Sbjct: 164 SLNSSRSQ 171
>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
Length = 372
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 48 SMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKEDNVLVESHEKSLGEADKADVN 107
+ +R + +R K++D+ ++ L R+ R+KED V + LG D D +
Sbjct: 109 AFQRPQLMRLKVKDLRQYLIL------RNIPIDTCREKEDLVDLVLCHHGLGSEDDMDTS 162
Query: 108 VLTKAKSQ 115
L ++SQ
Sbjct: 163 SLNSSRSQ 170
>gi|66730423 hypothetical protein LOC389384 [Homo sapiens]
Length = 652
Score = 26.9 bits (58), Expect = 3.5
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 43 GKHLNSMERVEWLRKK--LQDVHNFVALGAPLAPRDAGSQRPRKKE 86
G L S +R KK L+ + NF P PR+ S+RPR KE
Sbjct: 82 GDFLPSEQRPSQDTKKGWLKTMLNFFVRTGPEEPRERASRRPRGKE 127
>gi|4505683 platelet-derived growth factor receptor beta precursor
[Homo sapiens]
Length = 1106
Score = 26.6 bits (57), Expect = 4.5
Identities = 12/33 (36%), Positives = 21/33 (63%)
Query: 15 LAICFLTKSDGKSVKKRSVSEIQLMHNLGKHLN 47
+A+ L + S K+ +SE+++M +LG HLN
Sbjct: 631 VAVKMLKSTARSSEKQALMSELKIMSHLGPHLN 663
>gi|163644316 hypothetical protein LOC23255 [Homo sapiens]
Length = 1586
Score = 26.6 bits (57), Expect = 4.5
Identities = 20/72 (27%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 27 SVKKRSVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKE 86
S K + +++L+ L + +R EW R+K + + L +PR GS +K+
Sbjct: 918 SEKNWNREKVELLDRLDR-----DRQEWERQKKEFLWRIEQLQKENSPRRGGSFLCDQKD 972
Query: 87 DNVLVESHEKSL 98
NV H+ SL
Sbjct: 973 GNVRPFPHQGSL 984
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 26.2 bits (56), Expect = 5.9
Identities = 12/39 (30%), Positives = 20/39 (51%)
Query: 49 MERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKED 87
M V L+ + H +A+G+ A R+ + RP K +D
Sbjct: 701 MGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKD 739
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 26.2 bits (56), Expect = 5.9
Identities = 12/39 (30%), Positives = 20/39 (51%)
Query: 49 MERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKED 87
M V L+ + H +A+G+ A R+ + RP K +D
Sbjct: 701 MGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKD 739
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 26.2 bits (56), Expect = 5.9
Identities = 12/39 (30%), Positives = 20/39 (51%)
Query: 49 MERVEWLRKKLQDVHNFVALGAPLAPRDAGSQRPRKKED 87
M V L+ + H +A+G+ A R+ + RP K +D
Sbjct: 701 MGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKD 739
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 26.2 bits (56), Expect = 5.9
Identities = 13/28 (46%), Positives = 17/28 (60%)
Query: 20 LTKSDGKSVKKRSVSEIQLMHNLGKHLN 47
LTKS K +RSV +++L KHLN
Sbjct: 798 LTKSSSKRDHRRSVDSRNTLNDLLKHLN 825
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 26.2 bits (56), Expect = 5.9
Identities = 13/28 (46%), Positives = 17/28 (60%)
Query: 20 LTKSDGKSVKKRSVSEIQLMHNLGKHLN 47
LTKS K +RSV +++L KHLN
Sbjct: 860 LTKSSSKRDHRRSVDSRNTLNDLLKHLN 887
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,867,722
Number of Sequences: 37866
Number of extensions: 150352
Number of successful extensions: 495
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 467
Number of HSP's gapped (non-prelim): 42
length of query: 115
length of database: 18,247,518
effective HSP length: 85
effective length of query: 30
effective length of database: 15,028,908
effective search space: 450867240
effective search space used: 450867240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.