Guide to the Human Genome
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Search of human proteins with 4506123

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo
sapiens]
         (342 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo sap...   680   0.0  
gi|45439327 periplakin [Homo sapiens]                                  38   0.015
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s...    36   0.044
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...    36   0.044
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]      35   0.097
gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Hom...    35   0.097
gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Hom...    35   0.097
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom...    35   0.097
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    35   0.13 
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]     35   0.13 
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]         35   0.13 
gi|148746195 trichohyalin [Homo sapiens]                               34   0.17 
gi|42516576 glutaredoxin 5 [Homo sapiens]                              34   0.17 
gi|31542634 filamin A interacting protein 1 [Homo sapiens]             34   0.22 
gi|93102364 SWAP-70 protein [Homo sapiens]                             33   0.28 
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         33   0.28 
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         33   0.28 
gi|29648315 small G protein signaling modulator 3 [Homo sapiens]       33   0.28 
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa...    33   0.28 
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap...    33   0.28 
gi|153791492 eukaryotic translation initiation factor 3, subunit...    33   0.48 
gi|83700233 eukaryotic translation initiation factor 3, subunit ...    33   0.48 
gi|4503525 eukaryotic translation initiation factor 3, subunit C...    33   0.48 
gi|21361183 paired-like homeodomain transcription factor 2 isofo...    32   0.63 
gi|32698866 spindle pole body component 24 homolog [Homo sapiens]      32   0.63 
gi|24234711 paired-like homeodomain transcription factor 2 isofo...    32   0.82 
gi|24234708 paired-like homeodomain transcription factor 2 isofo...    32   0.82 
gi|126362971 serine/threonine kinase 10 [Homo sapiens]                 32   0.82 
gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]              32   0.82 
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    32   0.82 

>gi|4506123 PRP18 pre-mRNA processing factor 18 homolog [Homo
           sapiens]
          Length = 342

 Score =  680 bits (1755), Expect = 0.0
 Identities = 342/342 (100%), Positives = 342/342 (100%)

Query: 1   MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLT 60
           MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLT
Sbjct: 1   MDILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLT 60

Query: 61  SSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVN 120
           SSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVN
Sbjct: 61  SSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVN 120

Query: 121 KGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGD 180
           KGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGD
Sbjct: 121 KGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGD 180

Query: 181 DHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKR 240
           DHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKR
Sbjct: 181 DHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRKR 240

Query: 241 NLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSK 300
           NLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSK
Sbjct: 241 NLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIGVTMVGIHARTGREKIFSK 300

Query: 301 HVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL 342
           HVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL
Sbjct: 301 HVAHVLNDETQRKYIQGLKRLMTICQKHFPTDPSKCVEYNAL 342


>gi|45439327 periplakin [Homo sapiens]
          Length = 1756

 Score = 37.7 bits (86), Expect = 0.015
 Identities = 57/212 (26%), Positives = 96/212 (45%), Gaps = 28/212 (13%)

Query: 7   EILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVL 66
           E L+K     ++N++    K   +S+LA+ +E    E     +Q   + +K L     VL
Sbjct: 32  EQLQKNADQVEKNIVDTEAKM--QSDLARLQEGRQPEHRDVTLQKVLDSEKLLY----VL 85

Query: 67  ELELA---EEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGL 123
           E + A     K P      E IR+L+ER   +R      +    RL   E+  P+VN   
Sbjct: 86  EADAAIAKHMKHPQGDMIAEDIRQLKERVTNLR----GKHKQIYRLAVKEV-DPQVNWAA 140

Query: 124 RNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGK-GDDH 182
             + K  LDK++ Q           G +    D +V E N    E++A+G  L K GD  
Sbjct: 141 LVEEK--LDKLNNQSF---------GTDLPLVDHQVEEHNIFHNEVKAIGPHLAKDGDKE 189

Query: 183 KDMDIITKFLKFLLGVWAKE--LNAREDYVKR 212
           ++ ++  K+ K L    A++  L++ +DY++R
Sbjct: 190 QNSELRAKYQKLLAASQARQQHLSSLQDYMQR 221


>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
            sapiens]
          Length = 3118

 Score = 36.2 bits (82), Expect = 0.044
 Identities = 58/224 (25%), Positives = 99/224 (44%), Gaps = 30/224 (13%)

Query: 24   NKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQ--KPLTSSNPVLELELAEEKLPMTLSR 81
            N+K  K +E     +EA FER    +Q KE DQ  K L   N   + E+AE++L    + 
Sbjct: 1693 NEKAIKLNETLGTRDEA-FERNLEGLQ-KEIDQMIKELRRKNLETQKEIAEDELVAAEAL 1750

Query: 82   QEVIRRL--RERGEPIRLFGE-----TDY-----DAFQRLRKIEILTPEVNKGLRNDLKA 129
             + +++L    RGE   +  +      DY     DA+  LR+      E N+        
Sbjct: 1751 LKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLF------ 1804

Query: 130  ALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIIT 189
            A+++ +   L +     E G+   +N LK  E N  ++E   L + +    D+ + DI T
Sbjct: 1805 AVNQKNMTALEKKKEAVESGKRQIENTLK--EGNDILDEANRLADEINSIIDYVE-DIQT 1861

Query: 190  KFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPL 233
            K     L   ++ELN + D + + ++ +  +    Q ES+   L
Sbjct: 1862 K-----LPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQL 1900


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
            sapiens]
          Length = 3122

 Score = 36.2 bits (82), Expect = 0.044
 Identities = 58/224 (25%), Positives = 99/224 (44%), Gaps = 30/224 (13%)

Query: 24   NKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQ--KPLTSSNPVLELELAEEKLPMTLSR 81
            N+K  K +E     +EA FER    +Q KE DQ  K L   N   + E+AE++L    + 
Sbjct: 1693 NEKAIKLNETLGTRDEA-FERNLEGLQ-KEIDQMIKELRRKNLETQKEIAEDELVAAEAL 1750

Query: 82   QEVIRRL--RERGEPIRLFGE-----TDY-----DAFQRLRKIEILTPEVNKGLRNDLKA 129
             + +++L    RGE   +  +      DY     DA+  LR+      E N+        
Sbjct: 1751 LKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLF------ 1804

Query: 130  ALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIIT 189
            A+++ +   L +     E G+   +N LK  E N  ++E   L + +    D+ + DI T
Sbjct: 1805 AVNQKNMTALEKKKEAVESGKRQIENTLK--EGNDILDEANRLADEINSIIDYVE-DIQT 1861

Query: 190  KFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPL 233
            K     L   ++ELN + D + + ++ +  +    Q ES+   L
Sbjct: 1862 K-----LPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQL 1900


>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
          Length = 1217

 Score = 35.0 bits (79), Expect = 0.097
 Identities = 60/284 (21%), Positives = 111/284 (39%), Gaps = 41/284 (14%)

Query: 10  RKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLELE 69
           ++R+    R+ ++   K  K     +++ E  F      +Q  E     + S+   L+ E
Sbjct: 724 QQRKFKASRDSILSEMKMLKEK---RQQSEKTFMPKQRSLQSLEASLHAMESTRESLKAE 780

Query: 70  LAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKA 129
           L  + L       +  +R+    + IR   + +        K+E +   V   L  +L+ 
Sbjct: 781 LGTDLLSQLSLEDQ--KRVDALNDEIRQLQQENRQLLNERIKLEGIITRVETYLNENLRK 838

Query: 130 ALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLG------------ 177
            LD+++Q+ LNE+    E G   T    ++   N  +++  A  E L             
Sbjct: 839 RLDQVEQE-LNEL-RETEGGTVLTATTSELEAINKRVKDTMARSEDLDNSIDKTEAGIKE 896

Query: 178 --------KGDDHKDMDII---TKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQT 226
                   K  + + MD I   TK L+ +       L  +E+ +K+    +L S  Q+  
Sbjct: 897 LQKSMERWKNMEKEHMDAINHDTKELEKMTNRQGMLLKKKEECMKKI--RELGSLPQEAF 954

Query: 227 ESY----LRPLFRKLRKRNLPAD-----IKESITDIIKFMLQRE 261
           E Y    L+ LFRKL + N          K+++   + F  Q+E
Sbjct: 955 EKYQTLSLKQLFRKLEQCNTELKKYSHVNKKALDQFVNFSEQKE 998


>gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Homo
           sapiens]
          Length = 381

 Score = 35.0 bits (79), Expect = 0.097
 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 19/151 (12%)

Query: 102 DYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHE 161
           D +  QR+R+  IL  +       + KAA  + DQ+Y   ++   E  E     D+K +E
Sbjct: 92  DKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENE 151

Query: 162 ENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSA 221
                + LEA  E   K ++ K +    K  +       KE   +E+  K     K  S 
Sbjct: 152 RIKATKALEAWKEYQRKAEEQKKIQREEKLCQ-------KEKQIKEERKKI----KYKSL 200

Query: 222 TQKQTESYLRPLFR--------KLRKRNLPA 244
           T+      L P  R        KL++ ++PA
Sbjct: 201 TRNLASRNLAPKGRNSENIFTEKLKEDSIPA 231


>gi|75677567 dyslexia susceptibility 1 candidate 1 isoform b [Homo
           sapiens]
          Length = 376

 Score = 35.0 bits (79), Expect = 0.097
 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 19/151 (12%)

Query: 102 DYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHE 161
           D +  QR+R+  IL  +       + KAA  + DQ+Y   ++   E  E     D+K +E
Sbjct: 92  DKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENE 151

Query: 162 ENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSA 221
                + LEA  E   K ++ K +    K  +       KE   +E+  K     K  S 
Sbjct: 152 RIKATKALEAWKEYQRKAEEQKKIQREEKLCQ-------KEKQIKEERKKI----KYKSL 200

Query: 222 TQKQTESYLRPLFR--------KLRKRNLPA 244
           T+      L P  R        KL++ ++PA
Sbjct: 201 TRNLASRNLAPKGRNSENIFTEKLKEDSIPA 231


>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
           sapiens]
          Length = 420

 Score = 35.0 bits (79), Expect = 0.097
 Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 19/151 (12%)

Query: 102 DYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHE 161
           D +  QR+R+  IL  +       + KAA  + DQ+Y   ++   E  E     D+K +E
Sbjct: 92  DKEMMQRIREKSILQAQERAKEATEAKAAAKREDQKYALSVMMKIEEEERKKIEDMKENE 151

Query: 162 ENTTIEELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSA 221
                + LEA  E   K ++ K +    K  +       KE   +E+  K     K  S 
Sbjct: 152 RIKATKALEAWKEYQRKAEEQKKIQREEKLCQ-------KEKQIKEERKKI----KYKSL 200

Query: 222 TQKQTESYLRPLFR--------KLRKRNLPA 244
           T+      L P  R        KL++ ++PA
Sbjct: 201 TRNLASRNLAPKGRNSENIFTEKLKEDSIPA 231


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 51/227 (22%), Positives = 107/227 (47%), Gaps = 38/227 (16%)

Query: 16  EDRNLLVENKKYFKRSELAKKEEEAYF--ERCGYKIQP-KEEDQKPLTSSNPVLELELAE 72
           E++  ++E  K    SELA   ++  +  E+   ++Q  KE+ QK ++  N     +  +
Sbjct: 395 EEQGCVIEKLK----SELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEK 450

Query: 73  EKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKI-EILTPEVNKGLRNDLKAAL 131
           EKL +       I+ L+E+ E ++   +     ++ LR+I EIL  E+ +     +    
Sbjct: 451 EKLTLMFE----IQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESA-GKISQEF 505

Query: 132 DKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGK--GDDHK------ 183
           + + QQ  +++         + Q  L+     T   E +AL E++ +  G++ K      
Sbjct: 506 ESMKQQQASDV--------HELQQKLR-----TAFTEKDALLETVNRLQGENEKLLSQQE 552

Query: 184 ---DMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTE 227
              +++   K L+   GV+   L+ R+  +K  ++GK+NS T+++ +
Sbjct: 553 LVPELENTIKNLQEKNGVYLLSLSQRDTMLKE-LEGKINSLTEEKDD 598



 Score = 29.6 bits (65), Expect = 4.1
 Identities = 36/175 (20%), Positives = 82/175 (46%), Gaps = 14/175 (8%)

Query: 4   LKSEILRKRQLVEDRNLL-VENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSS 62
           L+  +++ + L ED+ +L  E K  ++ +     E++         +  KE+    +   
Sbjct: 666 LEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKED----VILK 721

Query: 63  NPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKG 122
             + +LE   +KL + +  Q+ + +L E  +  +LF +T    F +    E+      K 
Sbjct: 722 EHITQLE---KKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKD 778

Query: 123 LRNDLKA---ALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTI--EELEAL 172
           + N L+A   +L KI+++  N +   ++    + + ++K  +E + +  EEL++L
Sbjct: 779 VVNVLQAVGESLAKINEEKCN-LAFQRDEKVLELEKEIKCLQEESVVQCEELKSL 832


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 38/173 (21%), Positives = 78/173 (45%), Gaps = 9/173 (5%)

Query: 5   KSEILRKRQLVEDRNLLVENKKYFKRSELAKKE------EEAYFERCGYKIQPKEEDQKP 58
           ++EI+R   L +D +L  +N K   R E+ +KE      E+   +    K+  + E  K 
Sbjct: 398 ENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKS 457

Query: 59  LTSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPE 118
             + +  L+ EL + +L +    QE+ + + E+   I    E D    +  + + ++  +
Sbjct: 458 TATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQ 517

Query: 119 VNKGLRNDLKAALDKIDQQYLNE--IVGGQEPGEEDTQNDLKVHEENTTIEEL 169
           ++K  +N+  + + K+ Q   +E   V   E  + D   +L V +E     E+
Sbjct: 518 LSK-QQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEV 569


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 57/284 (20%), Positives = 122/284 (42%), Gaps = 39/284 (13%)

Query: 2   DILKSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTS 61
           +I++ +I ++ + ++ R+  +ENK     +E  K EEE   E+   ++Q K ++++    
Sbjct: 645 EIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETF-- 702

Query: 62  SNPVLELELAEEKLPMTLSRQEVIRRLR-----ERGEPIRLFGETDY---DAFQRLRKIE 113
                            L  QE ++RL+     E+ E  ++F E D    +  ++  K+E
Sbjct: 703 -----------------LRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLE 745

Query: 114 ILTPEVNKGLRND--LKAALD---KIDQQYLNEIVGGQEPGEEDTQNDLK-VHEENTTIE 167
           +    + +  +    L A L+   +  Q+ +  +  G+    E+ + DL+ + E    ++
Sbjct: 746 LEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVK 805

Query: 168 ELEALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTE 227
           E  A G+  G+  +   +    +F +F      K +N  +D V++  +  L    Q++ E
Sbjct: 806 EARAGGDEDGEELEKAQL----RFFEFKRRQLVKLVNLEKDLVQQ--KDILKKEVQEEQE 859

Query: 228 SYLRPLFRKLRKRNLPADIKESITDIIKFMLQREYVKANDAYLQ 271
                     ++  L     ES+TD+ +     E +K  +  LQ
Sbjct: 860 ILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQ 903


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 45/230 (19%), Positives = 97/230 (42%), Gaps = 14/230 (6%)

Query: 5   KSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYF-----ERCGYKIQPKEEDQKPL 59
           + + LR++Q  E R    E ++  +R E  ++  E        ER   +++ ++E+++  
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER-- 359

Query: 60  TSSNPVLELELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEV 119
                 L  E  EE+    L R++ +RR ++     +L  E      Q+LR+ + L  E 
Sbjct: 360 --REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417

Query: 120 NKGLRNDLKAAL--DKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLG 177
                  L+     ++ +Q++  E    +   E++ + D    EE T   E E   + L 
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477

Query: 178 KGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTE 227
           +  + +  +   ++LK       ++   RE  ++R  + +     ++Q E
Sbjct: 478 RDQEEERRE---RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524



 Score = 32.3 bits (72), Expect = 0.63
 Identities = 36/167 (21%), Positives = 77/167 (46%), Gaps = 12/167 (7%)

Query: 10   RKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLELE 69
            R +QL E+ + L E++      E  + +E+   ++  ++++ + + ++    + P L+ +
Sbjct: 845  RAQQLQEEEDGLQEDQ------ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898

Query: 70   LAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIE--ILTPEVNKGLRNDL 127
            L +E+  +    +E+ R  RE+    R   E  Y   ++L++ E  +L  E  K  R + 
Sbjct: 899  LRKEQQLLQEEEEELQREEREKRR--RQEQERQYREEEQLQQEEEQLLREEREKRRRQER 956

Query: 128  KAAL--DKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEAL 172
            +     DK  QQ   +++G +       + + K  EE    +E E L
Sbjct: 957  ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)

Query: 7   EILRKRQLVEDRNLLVENKKYFKRSELAK--KEEEAYFERCGYKIQPKEEDQKPLTSSNP 64
           E LR+R+L+E R    E K+  +R    +  +EEE    R    +  KEE++  L    P
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK--LQEEEP 265

Query: 65  VLELELAEEKLPMTLSRQEVIRRLRERGE 93
             + EL EE+  +    ++ +RR R+  E
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEE 294



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 42/174 (24%), Positives = 76/174 (43%), Gaps = 17/174 (9%)

Query: 5   KSEILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNP 64
           + E  R+++L  ++   +E +   KR E+ + E+E   E+   + +P+EE ++ L     
Sbjct: 581 REEERRQQRLKREQEERLEQR--LKREEVERLEQEERREQRLKREEPEEERRQQL----- 633

Query: 65  VLELELAEEKLPMTLSRQEVIR---RLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNK 121
            L+ E  EE+    L R++  R   RL+   E  RL      +  +  R+ E L  E  +
Sbjct: 634 -LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE-LAEEEQE 691

Query: 122 GLRNDLKAALDKIDQQYLNEIVGGQ-----EPGEEDTQNDLKVHEENTTIEELE 170
             R  +K+ + K   Q  +E    Q      P +++ Q   +  EE     E E
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745



 Score = 28.9 bits (63), Expect = 7.0
 Identities = 34/141 (24%), Positives = 66/141 (46%), Gaps = 10/141 (7%)

Query: 29  KRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRL 88
           +R +  ++E+E   ER   +++ +EE+++         +L   +E+    L ++E  +RL
Sbjct: 502 RREQQLRREQE---ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558

Query: 89  RERGEPIRLFGETDYDAFQRL-----RKIEILTPEVNKGLRNDLK-AALDKIDQQYLNE- 141
            +     RL  E +    Q L     R+ + L  E  + L   LK   +++++Q+   E 
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618

Query: 142 IVGGQEPGEEDTQNDLKVHEE 162
            +  +EP EE  Q  LK  E+
Sbjct: 619 RLKREEPEEERRQQLLKSEEQ 639


>gi|42516576 glutaredoxin 5 [Homo sapiens]
          Length = 157

 Score = 34.3 bits (77), Expect = 0.17
 Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 15/93 (16%)

Query: 95  IRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQYLN-EIVGGQEPGEEDT 153
           +RL G  DY A+  L       PE+ +G+++   +    I Q YLN E VGG +      
Sbjct: 77  LRLHGVRDYAAYNVLDD-----PELRQGIKD--YSNWPTIPQVYLNGEFVGGCDIL---- 125

Query: 154 QNDLKVHEENTTIEELEALGESLGKGDDHKDMD 186
              L++H+    +EEL+ LG      D+ KD D
Sbjct: 126 ---LQMHQNGDLVEELKKLGIHSALLDEKKDQD 155


>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
          Length = 1213

 Score = 33.9 bits (76), Expect = 0.22
 Identities = 54/230 (23%), Positives = 104/230 (45%), Gaps = 27/230 (11%)

Query: 19  NLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVL---ELELAEEKL 75
           NLL + ++  K+    +K  +A  E+   K   K  D+     S  ++   E ++  E+L
Sbjct: 202 NLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQL 261

Query: 76  PMTLSR-QEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKI 134
            +   + Q++ ++LRE  E ++       +  Q+L K+E+           D +    + 
Sbjct: 262 GLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEV-----------DFEHKASRF 310

Query: 135 DQQY--LNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMDIITKFL 192
            Q++  +N  +  QE    + Q  LK+      IEELE   ++L K ++    ++  K  
Sbjct: 311 SQEHEEMNAKLANQE--SHNRQLRLKLVGLTQRIEELEETNKNLQKAEEEL-QELRDKIA 367

Query: 193 KFLLG---VWAKELNAREDYVKRSVQGKLNSATQKQTESYLRPLFRKLRK 239
           K   G   + A+  N R+  ++  ++GK    T  +TES  R L +KL++
Sbjct: 368 KGECGNSSLMAEVENLRKRVLE--MEGKDEEIT--KTESQCRELRKKLQE 413


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 26/125 (20%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 9   LRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLEL 68
           LRK+QL E   L  + K+    +E  ++E EA  ++         E++K    +   L+ 
Sbjct: 326 LRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQA 385

Query: 69  ELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLK 128
             + E     L RQ++  ++ ++   +  +        QR+R++E +  ++ + L ++ +
Sbjct: 386 RFSTELEREKLIRQQMEEQVAQKSSELEQY-------LQRVRELEDMYLKLQEALEDERQ 438

Query: 129 AALDK 133
           A  D+
Sbjct: 439 ARQDE 443


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 52/250 (20%), Positives = 110/250 (44%), Gaps = 27/250 (10%)

Query: 10  RKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLE-- 67
           +++ + ++RN   E  K  K SE + +EE+    +   +  P ++D +  +     +E  
Sbjct: 714 KEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEES 773

Query: 68  --LELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRN 125
             L L E+++ +   +++ I+  +E+ E      E D      + K+E  T E  K +++
Sbjct: 774 IGLHLVEKEIDIE-KQEKHIKESKEKPEKRSQIKEKD------IEKMERKTFEKEKKIKH 826

Query: 126 DLKAALDKIDQQYLNEIVGG-QEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKD 184
           + K+  DK+D   L+E V   +E  +  + +  K H+E    +   A+ ++  +    + 
Sbjct: 827 EHKSEKDKLD---LSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREK 883

Query: 185 MDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTES--YLRPLFRKLRKRNL 242
           MD              KE   +E ++  S +  L     KQ+++  Y +    K ++++ 
Sbjct: 884 MD----------RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDR 933

Query: 243 PADIKESITD 252
             D KE   D
Sbjct: 934 ELDKKEKSRD 943


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 52/250 (20%), Positives = 110/250 (44%), Gaps = 27/250 (10%)

Query: 10  RKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLE-- 67
           +++ + ++RN   E  K  K SE + +EE+    +   +  P ++D +  +     +E  
Sbjct: 737 KEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEES 796

Query: 68  --LELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRN 125
             L L E+++ +   +++ I+  +E+ E      E D      + K+E  T E  K +++
Sbjct: 797 IGLHLVEKEIDIE-KQEKHIKESKEKPEKRSQIKEKD------IEKMERKTFEKEKKIKH 849

Query: 126 DLKAALDKIDQQYLNEIVGG-QEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKD 184
           + K+  DK+D   L+E V   +E  +  + +  K H+E    +   A+ ++  +    + 
Sbjct: 850 EHKSEKDKLD---LSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREK 906

Query: 185 MDIITKFLKFLLGVWAKELNAREDYVKRSVQGKLNSATQKQTES--YLRPLFRKLRKRNL 242
           MD              KE   +E ++  S +  L     KQ+++  Y +    K ++++ 
Sbjct: 907 MD----------RKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDR 956

Query: 243 PADIKESITD 252
             D KE   D
Sbjct: 957 ELDKKEKSRD 966


>gi|29648315 small G protein signaling modulator 3 [Homo sapiens]
          Length = 749

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 35/144 (24%), Positives = 64/144 (44%), Gaps = 36/144 (25%)

Query: 26  KYFKRSELAKKEEEAYFERCGYKIQPKEEDQ--KPLTSSNPVLE---------------- 67
           KY ++ E A+ + E Y++  G+++  +E D+    L +++P++E                
Sbjct: 27  KYTQKEESAE-QPEFYYDEFGFRVYKEEGDEPGSSLLANSPLMEDAPQRLRWQAHLEFTH 85

Query: 68  ----LELAEEKLPMTLSRQEVIRRLRERGEP--------IRLFGETDYDAFQRLRKIEIL 115
                +L  +K+ ++L R E +R L   G P        +RL G     A Q+ R  E+ 
Sbjct: 86  NHDVGDLTWDKIAVSLPRSEKLRSLVLAGIPHGMRPQLWMRLSG-----ALQKKRNSELS 140

Query: 116 TPEVNKGLRNDLKAALDKIDQQYL 139
             E+ K   ND   A  +I++  L
Sbjct: 141 YREIVKNSSNDETIAAKQIEKDLL 164


>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
           sapiens]
          Length = 1185

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 40/197 (20%), Positives = 89/197 (45%), Gaps = 19/197 (9%)

Query: 7   EILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVL 66
           E + +++ +E+R   +E K+Y      A    +   ++   +I  K+   +     N  L
Sbjct: 310 EAMAQKEDMEERITTLE-KRYLAAQREATSVHDLN-DKLENEIANKDSMHRQTEDKNRQL 367

Query: 67  E--LELAEEKLPMTLSRQEVI----RRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVN 120
           +  LELAE+KL  TL + E +      L +R   +    E   +  +RLR++E    E N
Sbjct: 368 QERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKN 427

Query: 121 KGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVH---------EENTTIEELEA 171
           + L+   +   +K+++++   +    +    ++   L++H         ++N+ + E+E+
Sbjct: 428 QELQRARQR--EKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVES 485

Query: 172 LGESLGKGDDHKDMDII 188
             + L +    KD  ++
Sbjct: 486 AKKQLEETQHDKDQLVL 502


>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
           sapiens]
          Length = 1202

 Score = 33.5 bits (75), Expect = 0.28
 Identities = 40/197 (20%), Positives = 89/197 (45%), Gaps = 19/197 (9%)

Query: 7   EILRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVL 66
           E + +++ +E+R   +E K+Y      A    +   ++   +I  K+   +     N  L
Sbjct: 310 EAMAQKEDMEERITTLE-KRYLAAQREATSVHDLN-DKLENEIANKDSMHRQTEDKNRQL 367

Query: 67  E--LELAEEKLPMTLSRQEVI----RRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVN 120
           +  LELAE+KL  TL + E +      L +R   +    E   +  +RLR++E    E N
Sbjct: 368 QERLELAEQKLQQTLRKAETLPEVEAELAQRVAALSKAEERHGNIEERLRQMEAQLEEKN 427

Query: 121 KGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVH---------EENTTIEELEA 171
           + L+   +   +K+++++   +    +    ++   L++H         ++N+ + E+E+
Sbjct: 428 QELQRARQR--EKMNEEHNKRLSDTVDKLLSESNERLQLHLKERMAALEDKNSLLREVES 485

Query: 172 LGESLGKGDDHKDMDII 188
             + L +    KD  ++
Sbjct: 486 AKKQLEETQHDKDQLVL 502


>gi|153791492 eukaryotic translation initiation factor 3, subunit
           C-like [Homo sapiens]
          Length = 914

 Score = 32.7 bits (73), Expect = 0.48
 Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 18/142 (12%)

Query: 111 KIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELE 170
           K  +L  E  +  +  +++A DK  ++  N I           +N +K+ +    +EE E
Sbjct: 33  KQPLLLSEDEEDTKRVVRSAKDKRFEELTNLI--------RTIRNAMKIRDVTKCLEEFE 84

Query: 171 ALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKL-NSATQKQTESY 229
            LG++ GK     D + + +F       + + L   EDY+    + K       K     
Sbjct: 85  LLGKAYGKAKSIVDKEGVPRF-------YIRILADLEDYLNELWEDKEGKKKMNKNNAKA 137

Query: 230 LRPLFRKLRKRNLPADIKESIT 251
           L  L +K+RK N   D +  IT
Sbjct: 138 LSTLRQKIRKYN--RDFESHIT 157


>gi|83700233 eukaryotic translation initiation factor 3, subunit C
           [Homo sapiens]
          Length = 913

 Score = 32.7 bits (73), Expect = 0.48
 Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 18/142 (12%)

Query: 111 KIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELE 170
           K  +L  E  +  +  +++A DK  ++  N I           +N +K+ +    +EE E
Sbjct: 33  KQPLLLSEDEEDTKRVVRSAKDKRFEELTNLI--------RTIRNAMKIRDVTKCLEEFE 84

Query: 171 ALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKL-NSATQKQTESY 229
            LG++ GK     D + + +F       + + L   EDY+    + K       K     
Sbjct: 85  LLGKAYGKAKSIVDKEGVPRF-------YIRILADLEDYLNELWEDKEGKKKMNKNNAKA 137

Query: 230 LRPLFRKLRKRNLPADIKESIT 251
           L  L +K+RK N   D +  IT
Sbjct: 138 LSTLRQKIRKYN--RDFESHIT 157


>gi|4503525 eukaryotic translation initiation factor 3, subunit C
           [Homo sapiens]
          Length = 913

 Score = 32.7 bits (73), Expect = 0.48
 Identities = 34/142 (23%), Positives = 59/142 (41%), Gaps = 18/142 (12%)

Query: 111 KIEILTPEVNKGLRNDLKAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELE 170
           K  +L  E  +  +  +++A DK  ++  N I           +N +K+ +    +EE E
Sbjct: 33  KQPLLLSEDEEDTKRVVRSAKDKRFEELTNLI--------RTIRNAMKIRDVTKCLEEFE 84

Query: 171 ALGESLGKGDDHKDMDIITKFLKFLLGVWAKELNAREDYVKRSVQGKL-NSATQKQTESY 229
            LG++ GK     D + + +F       + + L   EDY+    + K       K     
Sbjct: 85  LLGKAYGKAKSIVDKEGVPRF-------YIRILADLEDYLNELWEDKEGKKKMNKNNAKA 137

Query: 230 LRPLFRKLRKRNLPADIKESIT 251
           L  L +K+RK N   D +  IT
Sbjct: 138 LSTLRQKIRKYN--RDFESHIT 157


>gi|21361183 paired-like homeodomain transcription factor 2 isoform
           c [Homo sapiens]
          Length = 324

 Score = 32.3 bits (72), Expect = 0.63
 Identities = 24/93 (25%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 128 KAALDKIDQQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGD--DHKDM 185
           +AA     QQ  NE VG ++P ++  Q   + H  +  ++ELEA  +     D    +++
Sbjct: 66  EAAEKDKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEI 125

Query: 186 DIITKFLKFLLGVWAKELNAREDYVKRSVQGKL 218
            + T   +  + VW K   A+    +R+ Q +L
Sbjct: 126 AVWTNLTEARVRVWFKNRRAKWRKRERNQQAEL 158


>gi|32698866 spindle pole body component 24 homolog [Homo sapiens]
          Length = 197

 Score = 32.3 bits (72), Expect = 0.63
 Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 10/106 (9%)

Query: 86  RRLRERGEPI--RLFGETDYDAFQRLRKIEILTPEVNKGLRNDLKAALDKIDQQ--YLNE 141
           RRL  R E +  RL  ET   A ++LR+I  +  EV + L N    A +++ Q    L +
Sbjct: 28  RRLLGRHEQVVERLL-ETQDGAEKQLREILTMEKEVAQSLLN----AKEQVHQGGVELQQ 82

Query: 142 IVGG-QEPGEEDTQNDLKVHEENTTIEELEALGESLGKGDDHKDMD 186
           +  G QE GEEDT+    + +    +EEL+ +   L + +   D D
Sbjct: 83  LEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128


>gi|24234711 paired-like homeodomain transcription factor 2 isoform
           a [Homo sapiens]
          Length = 271

 Score = 32.0 bits (71), Expect = 0.82
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 136 QQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGD--DHKDMDIITKFLK 193
           QQ  NE VG ++P ++  Q   + H  +  ++ELEA  +     D    +++ + T   +
Sbjct: 21  QQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTE 80

Query: 194 FLLGVWAKELNAREDYVKRSVQGKL 218
             + VW K   A+    +R+ Q +L
Sbjct: 81  ARVRVWFKNRRAKWRKRERNQQAEL 105


>gi|24234708 paired-like homeodomain transcription factor 2 isoform
           b [Homo sapiens]
          Length = 317

 Score = 32.0 bits (71), Expect = 0.82
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 2/85 (2%)

Query: 136 QQYLNEIVGGQEPGEEDTQNDLKVHEENTTIEELEALGESLGKGD--DHKDMDIITKFLK 193
           QQ  NE VG ++P ++  Q   + H  +  ++ELEA  +     D    +++ + T   +
Sbjct: 67  QQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTE 126

Query: 194 FLLGVWAKELNAREDYVKRSVQGKL 218
             + VW K   A+    +R+ Q +L
Sbjct: 127 ARVRVWFKNRRAKWRKRERNQQAEL 151


>gi|126362971 serine/threonine kinase 10 [Homo sapiens]
          Length = 968

 Score = 32.0 bits (71), Expect = 0.82
 Identities = 34/146 (23%), Positives = 70/146 (47%), Gaps = 17/146 (11%)

Query: 9   LRKRQLVEDRNLLVENKKYFKRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLEL 68
           LR+++L E R  L++ +++  +++L+ K E    +   +K   +E + K       +  L
Sbjct: 561 LRRQELRELR--LLQKEEHRNQTQLSNKHELQLEQM--HKRFEQEINAKKKFFDTELENL 616

Query: 69  ELAEEKLPMTLSRQEVIRRLRERGEPIRLFGETDYDAFQRLRKIEILTPEVNKGLRNDLK 128
           E  +++    + +   +RR RE    IRL  + DY  FQ   K+          ++ ++K
Sbjct: 617 ERQQKQQVEKMEQDHAVRR-REEARRIRLEQDRDYTRFQEQLKL----------MKKEVK 665

Query: 129 AALDKIDQQYLNEIVGGQEPGEEDTQ 154
             ++K+ +Q   E +  ++  EE TQ
Sbjct: 666 NEVEKLPRQQRKESM--KQKMEEHTQ 689


>gi|33359215 ALS2 C-terminal like isoform 1 [Homo sapiens]
          Length = 953

 Score = 32.0 bits (71), Expect = 0.82
 Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 11/81 (13%)

Query: 239 KRNLPADIKESITDIIKFMLQREYVKANDAYLQMAIGNAPWPIG-------VTMVGIHAR 291
           +R  P D   S+ DI++ +LQ    KA   YL+ A+ N+  P+G       +T    +A 
Sbjct: 643 ERTHPEDSVGSMEDILEELLQHREPKALQLYLRKALSNSLHPLGKLLRTLMLTFQATYAG 702

Query: 292 TGREKIFSKHVAHVLNDETQR 312
            G     +KH+  +  +E ++
Sbjct: 703 VGA----NKHLQELAQEEVKQ 719


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 32.0 bits (71), Expect = 0.82
 Identities = 38/173 (21%), Positives = 77/173 (44%), Gaps = 20/173 (11%)

Query: 29  KRSELAKKEEEAYFERCGYKIQPKEEDQKPLTSSNPVLELELAEEKLPMTLSRQEVIRRL 88
           K+ E A++E+EA       K    E++   L      LE +L +    +  +  ++ +  
Sbjct: 299 KKCEEARQEKEAMV----MKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLS 354

Query: 89  RERGEPIRLFGETDYDAFQRLRKIEILTPEVN------KGLRNDLKAALD--KIDQQYLN 140
           +E+G   +L+   + +  + +R+I+ L  ++N      K  +N LKA +D  K  +  L 
Sbjct: 355 QEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLK 414

Query: 141 EIVGGQEPGEEDT-------QNDLKVHEENTTIEELEALGE-SLGKGDDHKDM 185
           E        +E+        Q+ +K ++E+  I+  E   +  + KG+  K M
Sbjct: 415 ETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQM 467


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,493,852
Number of Sequences: 37866
Number of extensions: 565978
Number of successful extensions: 2256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 2207
Number of HSP's gapped (non-prelim): 115
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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