Guide to the Human Genome
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Search of human proteins with 4506027

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506027 protein phosphatase 4, catalytic subunit [Homo
sapiens]
         (307 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]    636   0.0  
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo...   439   e-123
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor...   439   e-123
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo...   438   e-123
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H...   409   e-114
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ...   390   e-109
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ...   359   2e-99
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo...   295   4e-80
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof...   293   1e-79
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo...   293   1e-79
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo...   288   3e-78
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor...   288   3e-78
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof...   266   2e-71
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso...   224   6e-59
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo...   224   6e-59
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof...   224   7e-59
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof...   224   7e-59
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo...   224   7e-59
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]    221   8e-58
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso...   219   2e-57
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom...   215   5e-56
gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly...   208   4e-54
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly...   205   5e-53
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly...   205   5e-53
gi|23312374 protein phosphatase with EF hand calcium-binding dom...   133   2e-31
gi|23312380 protein phosphatase with EF hand calcium-binding dom...   122   5e-28
gi|23312386 serine/threonine protein phosphatase with EF-hand mo...   107   1e-23
gi|23312378 protein phosphatase with EF hand calcium-binding dom...    99   6e-21
gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]     30   3.5  
gi|38679914 mitochondrial distribution and morphology 20 [Homo s...    29   4.6  

>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
          Length = 307

 Score =  636 bits (1640), Expect = 0.0
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY 60
           MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY
Sbjct: 1   MAEISDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFY 60

Query: 61  DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI 120
           DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
Sbjct: 61  DLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI 120

Query: 121 TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI 180
           TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI
Sbjct: 121 TQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTI 180

Query: 181 DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL 240
           DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL
Sbjct: 181 DRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQL 240

Query: 241 VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK 300
           VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK
Sbjct: 241 VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKK 300

Query: 301 PVADYFL 307
           PVADYFL
Sbjct: 301 PVADYFL 307


>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  439 bits (1128), Expect = e-123
 Identities = 200/303 (66%), Positives = 248/303 (81%), Gaps = 3/303 (0%)

Query: 6   DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65
           +LD+ +EQL  C+ + E++V+ LC KA+EIL +ESNVQ V  PVTVCGD+HGQF+DL EL
Sbjct: 9   ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68

Query: 66  FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125
           FR+GG  P+TNYLFMGD+VDRG+YSVET  LL+ALKVRYP+RIT++RGNHESRQITQVYG
Sbjct: 69  FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128

Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185
           FYDECLRKYG+  VW+Y T++FDYL L+A++DG+IFC+HGGLSPSI TLD IR +DR QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188

Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245
           VPH+GPMCDLLWSDP+D  GWG+SPRGAGY FG D+   FN AN + ++ RAHQLVMEGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248

Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPS-KKPVAD 304
            W  +  V+T++SAPNYCYRCGN AAI+ELD+ L+  F+ F+ AP+  RG P   +   D
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEPHVTRRTPD 306

Query: 305 YFL 307
           YFL
Sbjct: 307 YFL 309


>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  439 bits (1128), Expect = e-123
 Identities = 200/303 (66%), Positives = 248/303 (81%), Gaps = 3/303 (0%)

Query: 6   DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65
           +LD+ +EQL  C+ + E++V+ LC KA+EIL +ESNVQ V  PVTVCGD+HGQF+DL EL
Sbjct: 9   ELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68

Query: 66  FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125
           FR+GG  P+TNYLFMGD+VDRG+YSVET  LL+ALKVRYP+RIT++RGNHESRQITQVYG
Sbjct: 69  FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYG 128

Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185
           FYDECLRKYG+  VW+Y T++FDYL L+A++DG+IFC+HGGLSPSI TLD IR +DR QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188

Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245
           VPH+GPMCDLLWSDP+D  GWG+SPRGAGY FG D+   FN AN + ++ RAHQLVMEGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248

Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPS-KKPVAD 304
            W  +  V+T++SAPNYCYRCGN AAI+ELD+ L+  F+ F+ AP+  RG P   +   D
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEPHVTRRTPD 306

Query: 305 YFL 307
           YFL
Sbjct: 307 YFL 309


>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
           [Homo sapiens]
          Length = 309

 Score =  438 bits (1127), Expect = e-123
 Identities = 202/303 (66%), Positives = 248/303 (81%), Gaps = 3/303 (0%)

Query: 6   DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65
           +LD+ IEQL  C+ + ES+VK+LC KA+EIL +ESNVQ V  PVTVCGD+HGQF+DL EL
Sbjct: 9   ELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMEL 68

Query: 66  FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125
           FR+GG  P+TNYLFMGD+VDRG+YSVET  LL+ALKVRY +RIT++RGNHESRQITQVYG
Sbjct: 69  FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG 128

Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185
           FYDECLRKYG+  VW+Y T++FDYL L+A++DG+IFC+HGGLSPSI TLD IR +DR QE
Sbjct: 129 FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQE 188

Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245
           VPH+GPMCDLLWSDP+D  GWG+SPRGAGY FG D+   FN AN + ++ RAHQLVMEGY
Sbjct: 189 VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGY 248

Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPS-KKPVAD 304
            W  +  V+T++SAPNYCYRCGN AAI+ELD+ L+  F+ F+ AP+  RG P   +   D
Sbjct: 249 NWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPR--RGEPHVTRRTPD 306

Query: 305 YFL 307
           YFL
Sbjct: 307 YFL 309


>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
           sapiens]
          Length = 305

 Score =  409 bits (1050), Expect = e-114
 Identities = 187/302 (61%), Positives = 236/302 (78%), Gaps = 1/302 (0%)

Query: 6   DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65
           DLD+ +E  R C+ + E+++K LC    ++L+EESNVQ V +PVTVCGDIHGQFYDL EL
Sbjct: 5   DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCEL 64

Query: 66  FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125
           FR GG VP+TNY+FMGDFVDRG+YS+ETF  LLALK ++PDRITL+RGNHESRQITQVYG
Sbjct: 65  FRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 124

Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185
           FYDEC  KYG+   WRYCT++FD L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE
Sbjct: 125 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 184

Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245
           +PH G  CDL+WSDPED   W +SPRGAG+LFG+ V  +F   N++ +ICRAHQLV EGY
Sbjct: 185 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 244

Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADY 305
           K+ F+E ++TVWSAPNYCYRCGN+A+I+   +   ++  +F A P   R IP  +    Y
Sbjct: 245 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPY 303

Query: 306 FL 307
           FL
Sbjct: 304 FL 305


>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
           [Homo sapiens]
          Length = 342

 Score =  390 bits (1003), Expect = e-109
 Identities = 179/280 (63%), Positives = 221/280 (78%), Gaps = 1/280 (0%)

Query: 28  LCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRG 87
           LC    ++L+EESNVQ V +PVTVCGDIHGQFYDL ELFR GG VP+TNY+FMGDFVDRG
Sbjct: 64  LCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIFMGDFVDRG 123

Query: 88  FYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIF 147
           +YS+ETF  LLALK ++PDRITL+RGNHESRQITQVYGFYDEC  KYG+   WRYCT++F
Sbjct: 124 YYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVF 183

Query: 148 DYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWG 207
           D L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE+PH G  CDL+WSDPED   W 
Sbjct: 184 DMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWA 243

Query: 208 VSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCG 267
           +SPRGAG+LFG+ V  +F   N++ +ICRAHQLV EGYK+ F+E ++TVWSAPNYCYRCG
Sbjct: 244 ISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCG 303

Query: 268 NVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADYFL 307
           N+A+I+   +   ++  +F A P   R IP  +    YFL
Sbjct: 304 NIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPYFL 342


>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
           [Homo sapiens]
          Length = 283

 Score =  359 bits (921), Expect = 2e-99
 Identities = 170/302 (56%), Positives = 217/302 (71%), Gaps = 23/302 (7%)

Query: 6   DLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKEL 65
           DLD+ +E  R C+ + E+++K LC    ++L+EESNVQ V +PVTVCGDIHGQ       
Sbjct: 5   DLDKYVEIARLCKYLPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQ------- 57

Query: 66  FRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125
                          GDFVDRG+YS+ETF  LLALK ++PDRITL+RGNHESRQITQVYG
Sbjct: 58  ---------------GDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYG 102

Query: 126 FYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE 185
           FYDEC  KYG+   WRYCT++FD L+++A+ID +I CVHGGLSP I+TLDQIRTI+R QE
Sbjct: 103 FYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQE 162

Query: 186 VPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGY 245
           +PH G  CDL+WSDPED   W +SPRGAG+LFG+ V  +F   N++ +ICRAHQLV EGY
Sbjct: 163 IPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGY 222

Query: 246 KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAAPQETRGIPSKKPVADY 305
           K+ F+E ++TVWSAPNYCYRCGN+A+I+   +   ++  +F A P   R IP  +    Y
Sbjct: 223 KFMFDEKLVTVWSAPNYCYRCGNIASIMVFKDVNTREPKLFRAVPDSERVIP-PRTTTPY 281

Query: 306 FL 307
           FL
Sbjct: 282 FL 283


>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
           [Homo sapiens]
          Length = 323

 Score =  295 bits (754), Expect = 4e-80
 Identities = 136/282 (48%), Positives = 199/282 (70%), Gaps = 6/282 (2%)

Query: 20  IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
           ++E+E++ LC K+REI + +  +  +++P+ +CGDIHGQ+YDL  LF  GG  PE+NYLF
Sbjct: 30  LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 80  MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
           +GD+VDRG  S+ET  LLLA K++YP+   L+RGNHE   I ++YGFYDEC R+Y ++ +
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148

Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
           W+  T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSD
Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208

Query: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258
           P+ D  GWG + RG  + FG++VVA+F   +D+D+ICRAHQ+V +GY++     ++T++S
Sbjct: 209 PDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268

Query: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAA----PQETRGI 296
           APNYC    N  A++ +DE L   F I + A    P  TR +
Sbjct: 269 APNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPV 310


>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
           3 [Homo sapiens]
          Length = 341

 Score =  293 bits (750), Expect = 1e-79
 Identities = 133/271 (49%), Positives = 194/271 (71%), Gaps = 2/271 (0%)

Query: 20  IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
           + E+E++ LC K+REI + +  +  +++P+ +CGDIHGQ+YDL  LF  GG  PE+NYLF
Sbjct: 41  LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 100

Query: 80  MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
           +GD+VDRG  S+ET  LLLA K++YP+   L+RGNHE   I ++YGFYDEC R+Y ++ +
Sbjct: 101 LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 159

Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
           W+  T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSD
Sbjct: 160 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 219

Query: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258
           P+ D  GWG + RG  + FG++VVA+F   +D+D+ICRAHQ+V +GY++     ++T++S
Sbjct: 220 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 279

Query: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAA 289
           APNYC    N  A++ +DE L   F I + A
Sbjct: 280 APNYCGEFDNAGAMMSVDETLMCSFQILKPA 310


>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
           1 [Homo sapiens]
          Length = 330

 Score =  293 bits (750), Expect = 1e-79
 Identities = 133/271 (49%), Positives = 194/271 (71%), Gaps = 2/271 (0%)

Query: 20  IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
           + E+E++ LC K+REI + +  +  +++P+ +CGDIHGQ+YDL  LF  GG  PE+NYLF
Sbjct: 30  LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 80  MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
           +GD+VDRG  S+ET  LLLA K++YP+   L+RGNHE   I ++YGFYDEC R+Y ++ +
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY-NIKL 148

Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
           W+  T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSD
Sbjct: 149 WKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSD 208

Query: 200 PE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWS 258
           P+ D  GWG + RG  + FG++VVA+F   +D+D+ICRAHQ+V +GY++     ++T++S
Sbjct: 209 PDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFS 268

Query: 259 APNYCYRCGNVAAILELDEHLQKDFIIFEAA 289
           APNYC    N  A++ +DE L   F I + A
Sbjct: 269 APNYCGEFDNAGAMMSVDETLMCSFQILKPA 299


>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
           1 [Homo sapiens]
          Length = 327

 Score =  288 bits (738), Expect = 3e-78
 Identities = 134/286 (46%), Positives = 199/286 (69%), Gaps = 6/286 (2%)

Query: 22  ESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMG 81
           E+EV+ LC K+REI + +  +  +++P+ +CGDIHGQ+ DL  LF  GG  PE NYLF+G
Sbjct: 31  EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLG 90

Query: 82  DFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWR 141
           D+VDRG  S+ET  LLLA K++YP+   L+RGNHE   I ++YGFYDEC R++ ++ +W+
Sbjct: 91  DYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWK 149

Query: 142 YCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE 201
             T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSDP+
Sbjct: 150 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPD 209

Query: 202 -DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAP 260
            D  GWG + RG  + FG+DVV++F   +D+D+ICRAHQ+V +GY++     ++T++SAP
Sbjct: 210 KDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 269

Query: 261 NYCYRCGNVAAILELDEHLQKDFIIFEAAPQETR----GIPSKKPV 302
           NYC    N   ++ +DE L   F I + + ++ +    G+ S +PV
Sbjct: 270 NYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPV 315


>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
           [Homo sapiens]
          Length = 327

 Score =  288 bits (738), Expect = 3e-78
 Identities = 134/286 (46%), Positives = 199/286 (69%), Gaps = 6/286 (2%)

Query: 22  ESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMG 81
           E+EV+ LC K+REI + +  +  +++P+ +CGDIHGQ+ DL  LF  GG  PE NYLF+G
Sbjct: 31  EAEVRGLCIKSREIFLSQPILLELEAPLKICGDIHGQYTDLLRLFEYGGFPPEANYLFLG 90

Query: 82  DFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWR 141
           D+VDRG  S+ET  LLLA K++YP+   L+RGNHE   I ++YGFYDEC R++ ++ +W+
Sbjct: 91  DYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRF-NIKLWK 149

Query: 142 YCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPE 201
             T+ F+ L ++AI+D KIFC HGGLSP +Q+++QIR I R  +VP  G +CDLLWSDP+
Sbjct: 150 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDTGLLCDLLWSDPD 209

Query: 202 -DTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAP 260
            D  GWG + RG  + FG+DVV++F   +D+D+ICRAHQ+V +GY++     ++T++SAP
Sbjct: 210 KDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 269

Query: 261 NYCYRCGNVAAILELDEHLQKDFIIFEAAPQETR----GIPSKKPV 302
           NYC    N   ++ +DE L   F I + + ++ +    G+ S +PV
Sbjct: 270 NYCGEFDNAGGMMSVDETLMCSFQILKPSEKKAKYQYGGLNSGRPV 315


>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
           2 [Homo sapiens]
          Length = 286

 Score =  266 bits (680), Expect = 2e-71
 Identities = 123/238 (51%), Positives = 171/238 (71%), Gaps = 2/238 (0%)

Query: 53  GDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIR 112
           GDIHGQ+YDL  LF  GG  PE+NYLF+GD+VDRG  S+ET  LLLA K++YP+   L+R
Sbjct: 19  GDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLR 78

Query: 113 GNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQ 172
           GNHE   I ++YGFYDEC R+Y ++ +W+  T+ F+ L ++AI+D KIFC HGGLSP +Q
Sbjct: 79  GNHECASINRIYGFYDECKRRY-NIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ 137

Query: 173 TLDQIRTIDRKQEVPHDGPMCDLLWSDPE-DTTGWGVSPRGAGYLFGSDVVAQFNAANDI 231
           +++QIR I R  +VP  G +CDLLWSDP+ D  GWG + RG  + FG++VVA+F   +D+
Sbjct: 138 SMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDL 197

Query: 232 DMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEAA 289
           D+ICRAHQ+V +GY++     ++T++SAPNYC    N  A++ +DE L   F I + A
Sbjct: 198 DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPA 255


>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 2 [Homo sapiens]
          Length = 511

 Score =  224 bits (572), Expect = 6e-59
 Identities = 117/274 (42%), Positives = 167/274 (60%), Gaps = 15/274 (5%)

Query: 20  IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
           ++ES    +  +   IL +E N+  +D+PVTVCGDIHGQF+DL +LF VGG    T YLF
Sbjct: 56  LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115

Query: 80  MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
           +GD+VDRG++S+E  L L ALK+ YP  + L+RGNHE R +T+ + F  EC  KY S  V
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174

Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
           +  C + FD L L+A+++ +  CVHGGLSP I TLD IR +DR +E P  GPMCD+LWSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234

Query: 200 PEDTTG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251
           P +  G           + RG  Y +    V +F   N++  I RAH+    GY+ +   
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294

Query: 252 ------TVLTVWSAPNYCYRCGNVAAILELDEHL 279
                 +++T++SAPNY     N AA+L+ + ++
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 328


>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
           isoform 1 [Homo sapiens]
          Length = 521

 Score =  224 bits (572), Expect = 6e-59
 Identities = 117/274 (42%), Positives = 167/274 (60%), Gaps = 15/274 (5%)

Query: 20  IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
           ++ES    +  +   IL +E N+  +D+PVTVCGDIHGQF+DL +LF VGG    T YLF
Sbjct: 56  LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115

Query: 80  MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
           +GD+VDRG++S+E  L L ALK+ YP  + L+RGNHE R +T+ + F  EC  KY S  V
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174

Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
           +  C + FD L L+A+++ +  CVHGGLSP I TLD IR +DR +E P  GPMCD+LWSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234

Query: 200 PEDTTG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251
           P +  G           + RG  Y +    V +F   N++  I RAH+    GY+ +   
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294

Query: 252 ------TVLTVWSAPNYCYRCGNVAAILELDEHL 279
                 +++T++SAPNY     N AA+L+ + ++
Sbjct: 295 QTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 328


>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
           c [Homo sapiens]
          Length = 515

 Score =  224 bits (571), Expect = 7e-59
 Identities = 125/298 (41%), Positives = 175/298 (58%), Gaps = 23/298 (7%)

Query: 3   EISDLDR--QIEQLRRCELIKESEVKALCA-----KAREILVEESNVQRVDSPVTVCGDI 55
           E+ DLD   +++ L+   L+KE  V    A     +   IL  E  +  V++P+TVCGDI
Sbjct: 42  EVFDLDGIPRVDVLKN-HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDI 100

Query: 56  HGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH 115
           HGQF+DL +LF VGG    T YLF+GD+VDRG++S+E  L L  LK+ YP  + L+RGNH
Sbjct: 101 HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNH 160

Query: 116 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD 175
           E R +T+ + F  EC  KY S  V+  C E FD L L+A+++ +  CVHGGLSP I TLD
Sbjct: 161 ECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLD 219

Query: 176 QIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSP--------RGAGYLFGSDVVAQFNA 227
            IR +DR +E P  GPMCDLLWSDP +  G   S         RG  Y +    V +F  
Sbjct: 220 DIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQ 279

Query: 228 ANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAPNYCYRCGNVAAILELDEHL 279
            N++  I RAH+    GY+ +         +++T++SAPNY     N AA+L+ + ++
Sbjct: 280 NNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 337


>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
           a [Homo sapiens]
          Length = 525

 Score =  224 bits (571), Expect = 7e-59
 Identities = 125/298 (41%), Positives = 175/298 (58%), Gaps = 23/298 (7%)

Query: 3   EISDLDR--QIEQLRRCELIKESEVKALCA-----KAREILVEESNVQRVDSPVTVCGDI 55
           E+ DLD   +++ L+   L+KE  V    A     +   IL  E  +  V++P+TVCGDI
Sbjct: 42  EVFDLDGIPRVDVLKN-HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDI 100

Query: 56  HGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH 115
           HGQF+DL +LF VGG    T YLF+GD+VDRG++S+E  L L  LK+ YP  + L+RGNH
Sbjct: 101 HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNH 160

Query: 116 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD 175
           E R +T+ + F  EC  KY S  V+  C E FD L L+A+++ +  CVHGGLSP I TLD
Sbjct: 161 ECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLD 219

Query: 176 QIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSP--------RGAGYLFGSDVVAQFNA 227
            IR +DR +E P  GPMCDLLWSDP +  G   S         RG  Y +    V +F  
Sbjct: 220 DIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQ 279

Query: 228 ANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAPNYCYRCGNVAAILELDEHL 279
            N++  I RAH+    GY+ +         +++T++SAPNY     N AA+L+ + ++
Sbjct: 280 NNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 337


>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
           b [Homo sapiens]
          Length = 524

 Score =  224 bits (571), Expect = 7e-59
 Identities = 125/298 (41%), Positives = 175/298 (58%), Gaps = 23/298 (7%)

Query: 3   EISDLDR--QIEQLRRCELIKESEVKALCA-----KAREILVEESNVQRVDSPVTVCGDI 55
           E+ DLD   +++ L+   L+KE  V    A     +   IL  E  +  V++P+TVCGDI
Sbjct: 42  EVFDLDGIPRVDVLKN-HLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDI 100

Query: 56  HGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH 115
           HGQF+DL +LF VGG    T YLF+GD+VDRG++S+E  L L  LK+ YP  + L+RGNH
Sbjct: 101 HGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNH 160

Query: 116 ESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLD 175
           E R +T+ + F  EC  KY S  V+  C E FD L L+A+++ +  CVHGGLSP I TLD
Sbjct: 161 ECRHLTEYFTFKQECKIKY-SERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLD 219

Query: 176 QIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSP--------RGAGYLFGSDVVAQFNA 227
            IR +DR +E P  GPMCDLLWSDP +  G   S         RG  Y +    V +F  
Sbjct: 220 DIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQ 279

Query: 228 ANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAPNYCYRCGNVAAILELDEHL 279
            N++  I RAH+    GY+ +         +++T++SAPNY     N AA+L+ + ++
Sbjct: 280 NNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNV 337


>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
          Length = 499

 Score =  221 bits (562), Expect = 8e-58
 Identities = 123/292 (42%), Positives = 173/292 (59%), Gaps = 12/292 (4%)

Query: 15  RRCELIKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPE 74
           R+C      +VK + +K   ++  E+ ++  +  +TVCGD HGQFYDL  +F + G   E
Sbjct: 206 RKCAYQILVQVKEVLSKLSTLV--ETTLKETEK-ITVCGDTHGQFYDLLNIFELNGLPSE 262

Query: 75  TN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRK 133
           TN Y+F GDFVDRG +SVE  L L   K+ YPD   L+RGNHE+  + Q+YGF  E   K
Sbjct: 263 TNPYIFNGDFVDRGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAK 322

Query: 134 YGSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGL-SPSIQTLDQIRTIDRKQEVPHDGPM 192
           Y +  ++   +E+F++L L+  I+GK+  +HGGL S    TLD IR I+R ++ P  GPM
Sbjct: 323 Y-TAQMYELFSEVFEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPM 381

Query: 193 CDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252
           CDLLWSDP+   G  +S RG    FG DV   F   N++D I R+H++  EGY+      
Sbjct: 382 CDLLWSDPQPQNGRSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGR 441

Query: 253 VLTVWSAPNYCYRCGNVAAILELD-EHLQKDFIIFEAAPQETRGIPSKKPVA 303
            +TV+SAPNYC + GN A+ + L    L+  F  F A P      P+ KP+A
Sbjct: 442 CVTVFSAPNYCDQMGNKASYIHLQGSDLRPQFHQFTAVPH-----PNVKPMA 488


>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 3 [Homo sapiens]
          Length = 469

 Score =  219 bits (558), Expect = 2e-57
 Identities = 113/257 (43%), Positives = 158/257 (61%), Gaps = 15/257 (5%)

Query: 20  IKESEVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLF 79
           ++ES    +  +   IL +E N+  +D+PVTVCGDIHGQF+DL +LF VGG    T YLF
Sbjct: 56  LEESVALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLF 115

Query: 80  MGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTV 139
           +GD+VDRG++S+E  L L ALK+ YP  + L+RGNHE R +T+ + F  EC  KY S  V
Sbjct: 116 LGDYVDRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKY-SERV 174

Query: 140 WRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSD 199
           +  C + FD L L+A+++ +  CVHGGLSP I TLD IR +DR +E P  GPMCD+LWSD
Sbjct: 175 YDACMDAFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSD 234

Query: 200 PEDTTG--------WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE 251
           P +  G           + RG  Y +    V +F   N++  I RAH+    GY+ +   
Sbjct: 235 PLEDFGNEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKS 294

Query: 252 ------TVLTVWSAPNY 262
                 +++T++SAPNY
Sbjct: 295 QTTGFPSLITIFSAPNY 311


>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
           sapiens]
          Length = 512

 Score =  215 bits (547), Expect = 5e-56
 Identities = 111/259 (42%), Positives = 158/259 (61%), Gaps = 15/259 (5%)

Query: 35  ILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDFVDRGFYSVETF 94
           IL +E  +  VD+P+TVCGDIHGQF+DL +LF VGG    T YLF+GD+VDRG++S+E  
Sbjct: 67  ILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGYFSIECV 126

Query: 95  LLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYLSLSA 154
           L L +LK+ +P  + L+RGNHE R +T  + F  EC  KY S  V+  C E FD L L+A
Sbjct: 127 LYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKY-SEQVYDACMETFDCLPLAA 185

Query: 155 IIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTG--------W 206
           +++ +  CVHGG+SP I +LD IR +DR  E P  GP+CDLLWSDP +  G         
Sbjct: 186 LLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEKTLEHYT 245

Query: 207 GVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNE------TVLTVWSAP 260
             + RG  Y +    V +F   N++  I RAH+    GY+ +         +++T++SAP
Sbjct: 246 HNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLITIFSAP 305

Query: 261 NYCYRCGNVAAILELDEHL 279
           NY     N AA+L+ + ++
Sbjct: 306 NYLDVYNNKAAVLKYENNV 324


>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 384

 Score =  208 bits (530), Expect = 4e-54
 Identities = 111/251 (44%), Positives = 150/251 (59%), Gaps = 55/251 (21%)

Query: 24  EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83
           +VK+LC +A+EIL EESN Q V  PVTV GD HGQ                      GD+
Sbjct: 176 KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 213

Query: 84  VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143
           +DRG+YS+E  +LLLA+KV Y + +T++  NHESRQITQVY  Y+ECLRK+G        
Sbjct: 214 IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 265

Query: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203
                    +A  DG++FC+HGGLSPS+ TL  IRT++  Q++PH+GPM DLL+SDP+D 
Sbjct: 266 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 315

Query: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263
                           D    FN A+ + ++ RAHQLVM G+ W  +  V+ ++S PNYC
Sbjct: 316 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 360

Query: 264 YRCGNVAAILE 274
           Y CG +A  L+
Sbjct: 361 YHCGGMALALQ 371


>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  205 bits (521), Expect = 5e-53
 Identities = 109/244 (44%), Positives = 146/244 (59%), Gaps = 55/244 (22%)

Query: 24  EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83
           +VK+LC +A+EIL EESN Q V  PVTV GD HGQ                      GD+
Sbjct: 55  KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 92

Query: 84  VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143
           +DRG+YS+E  +LLLA+KV Y + +T++  NHESRQITQVY  Y+ECLRK+G        
Sbjct: 93  IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 144

Query: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203
                    +A  DG++FC+HGGLSPS+ TL  IRT++  Q++PH+GPM DLL+SDP+D 
Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 194

Query: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263
                           D    FN A+ + ++ RAHQLVM G+ W  +  V+ ++S PNYC
Sbjct: 195 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239

Query: 264 YRCG 267
           Y CG
Sbjct: 240 YHCG 243


>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  205 bits (521), Expect = 5e-53
 Identities = 109/244 (44%), Positives = 146/244 (59%), Gaps = 55/244 (22%)

Query: 24  EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83
           +VK+LC +A+EIL EESN Q V  PVTV GD HGQ                      GD+
Sbjct: 55  KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 92

Query: 84  VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143
           +DRG+YS+E  +LLLA+KV Y + +T++  NHESRQITQVY  Y+ECLRK+G        
Sbjct: 93  IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 144

Query: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203
                    +A  DG++FC+HGGLSPS+ TL  IRT++  Q++PH+GPM DLL+SDP+D 
Sbjct: 145 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 194

Query: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263
                           D    FN A+ + ++ RAHQLVM G+ W  +  V+ ++S PNYC
Sbjct: 195 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 239

Query: 264 YRCG 267
           Y CG
Sbjct: 240 YHCG 243


>gi|23312374 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1b [Homo sapiens]
          Length = 625

 Score =  133 bits (335), Expect = 2e-31
 Identities = 89/295 (30%), Positives = 149/295 (50%), Gaps = 25/295 (8%)

Query: 5   SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60
           +D+D  +E  +  +++    V  +  + +++L +  N   + +     VT+CGD+HG+  
Sbjct: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178

Query: 61  DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119
           DL  +F   G   E N Y+F GDFVDRG  S+E  ++L    + YP+ + L RGNHE   
Sbjct: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238

Query: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177
           +   YGF  E L KY      + +   E + +L +  I+D +I  +HGG+S +   L+ +
Sbjct: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297

Query: 178 RTIDRKQE----VP-------HD-----GPMCDLLWSDPEDTTG-WGVSPRGAGYLFGSD 220
             ++R +     +P       HD       + D+LWSDP    G +  + RG G  FG D
Sbjct: 298 HRVERNKMKSVLIPPTETNRDHDTDSKHNKIIDILWSDPRGKNGCFPNTCRGGGCYFGPD 357

Query: 221 VVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL 275
           V ++      + M+ R+H+   EGY+   +  V+T++SA NY     N  A ++L
Sbjct: 358 VTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNYYEEGSNRGAYIKL 412


>gi|23312380 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1 [Homo sapiens]
          Length = 653

 Score =  122 bits (305), Expect = 5e-28
 Identities = 89/323 (27%), Positives = 149/323 (46%), Gaps = 53/323 (16%)

Query: 5   SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60
           +D+D  +E  +  +++    V  +  + +++L +  N   + +     VT+CGD+HG+  
Sbjct: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178

Query: 61  DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119
           DL  +F   G   E N Y+F GDFVDRG  S+E  ++L    + YP+ + L RGNHE   
Sbjct: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238

Query: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177
           +   YGF  E L KY      + +   E + +L +  I+D +I  +HGG+S +   L+ +
Sbjct: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297

Query: 178 RTIDRKQE----VP-------HD---------------------------------GPMC 193
             ++R +     +P       HD                                   + 
Sbjct: 298 HRVERNKMKSVLIPPTETNRDHDTDSKHNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQII 357

Query: 194 DLLWSDPEDTTG-WGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252
           D+LWSDP    G +  + RG G  FG DV ++      + M+ R+H+   EGY+   +  
Sbjct: 358 DILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGK 417

Query: 253 VLTVWSAPNYCYRCGNVAAILEL 275
           V+T++SA NY     N  A ++L
Sbjct: 418 VVTIFSASNYYEEGSNRGAYIKL 440


>gi|23312386 serine/threonine protein phosphatase with EF-hand
           motifs 2 [Homo sapiens]
          Length = 753

 Score =  107 bits (268), Expect = 1e-23
 Identities = 67/183 (36%), Positives = 99/183 (54%), Gaps = 8/183 (4%)

Query: 11  IEQLRRCELIKESEVKALCAKAREILVEESNVQRVDS----PVTVCGDIHGQFYDLKELF 66
           +E  R  + +    V  L  + ++ LV+  N+ RV +     +TVCGD+HGQ  DL  +F
Sbjct: 132 VEAFRLKQQLHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIF 191

Query: 67  RVGG-DVPETNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG 125
              G   PE +Y+F GDFVDRG  SVE  ++L A  + YP    L RGNHE   +   YG
Sbjct: 192 YKNGLPSPERSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYG 251

Query: 126 FYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRK 183
           F  E + KY      + R   ++F +L L+ +ID K+  +HGG+S  I  L+ +  I+R 
Sbjct: 252 FTKEVMNKYKVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVS-DITDLELLDKIERS 310

Query: 184 QEV 186
           + V
Sbjct: 311 KIV 313



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 1/96 (1%)

Query: 194 DLLWSDPEDTTGWGVSP-RGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNET 252
           D+LWSDP    G   +  RG G  FG DV  Q     ++  + R+H+   EGY++  N  
Sbjct: 443 DILWSDPMAQEGCKANTIRGGGCYFGPDVTQQLLQKYNMQFLIRSHECKPEGYEFCHNRK 502

Query: 253 VLTVWSAPNYCYRCGNVAAILELDEHLQKDFIIFEA 288
           VLT++SA NY     N  A ++L   L    + ++A
Sbjct: 503 VLTIFSASNYYEVGSNRGAYVKLGPALTPHIVQYQA 538


>gi|23312378 protein phosphatase with EF hand calcium-binding domain
           1 isoform 3 [Homo sapiens]
          Length = 591

 Score = 98.6 bits (244), Expect = 6e-21
 Identities = 77/278 (27%), Positives = 129/278 (46%), Gaps = 25/278 (8%)

Query: 5   SDLDRQIEQLRRCELIKESEVKALCAKAREILVEESNVQRVDSP----VTVCGDIHGQFY 60
           +D+D  +E  +  +++    V  +  + +++L +  N   + +     VT+CGD+HG+  
Sbjct: 119 TDIDLLLEAFKEQQILHAHYVLEVLFETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLD 178

Query: 61  DLKELFRVGGDVPETN-YLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ 119
           DL  +F   G   E N Y+F GDFVDRG  S+E  ++L    + YP+ + L RGNHE   
Sbjct: 179 DLFLIFYKNGLPSERNPYVFNGDFVDRGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFM 238

Query: 120 ITQVYGFYDECLRKY--GSVTVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQI 177
           +   YGF  E L KY      + +   E + +L +  I+D +I  +HGG+S +   L+ +
Sbjct: 239 MNLRYGFTKEILHKYKLHGKRILQILEEFYAWLPIGTIVDNEILVIHGGISETTD-LNLL 297

Query: 178 RTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRA 237
             ++R +       M  +L    E         +       + V   FNA   I    + 
Sbjct: 298 HRVERNK-------MKSVLIPPTETNRDHDTDSK------HNKVGVTFNAHGRI----KT 340

Query: 238 HQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL 275
           +    E    H  E V+T++SA NY     N  A ++L
Sbjct: 341 NGSPTEHLTEHEWEQVVTIFSASNYYEEGSNRGAYIKL 378


>gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]
          Length = 618

 Score = 29.6 bits (65), Expect = 3.5
 Identities = 17/57 (29%), Positives = 24/57 (42%)

Query: 165 GGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDTTGWGVSPRGAGYLFGSDV 221
           G   PS+  L       R QE   DGP   + W+ PED    G+    A  ++  +V
Sbjct: 531 GTPEPSVHALPDALNNLRTQEGSGDGPSSSVDWNRPEDVDPQGIYVISAPSIYAREV 587


>gi|38679914 mitochondrial distribution and morphology 20 [Homo
           sapiens]
          Length = 972

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 14/74 (18%), Positives = 34/74 (45%)

Query: 91  VETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYCTEIFDYL 150
           VE + ++L    +Y + + +IRG    +  +++    ++C+  Y  ++ W  C  +   L
Sbjct: 196 VELYYMILERLGKYQEALDVIRGKLGEKLTSEIQSRENKCMAMYKKLSRWPECNALSRRL 255

Query: 151 SLSAIIDGKIFCVH 164
            L    D + +  +
Sbjct: 256 LLKNSDDWQFYLTY 269


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.141    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,928,363
Number of Sequences: 37866
Number of extensions: 517301
Number of successful extensions: 1042
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 950
Number of HSP's gapped (non-prelim): 36
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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