Guide to the Human Genome
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Name: POLG Sequence: fasta or formatted (1239aa) NCBI GI: 4505937
Description:

DNA-directed DNA polymerase gamma

Referenced in:

DNA Polymerases
Mitochondria

Other entries for this name:
alt mRNA [1239aa] DNA-directed DNA polymerase gamma
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.3        103           2
 C cysteine            1.6         20           2
 D aspartate           4.6         57           2
 E glutamate           7.3         91           4
 F phenylalanine       2.6         32           2
 G glycine             7.4         92           2
 H histidine           2.3         29           2
 I isoleucine          3.1         39           2
 K lysine              4.7         58           2
 L leucine            10.4        129           3
 M methionine          2.7         34           1
 N asparagine          2.2         27           1
 P proline             7.2         89           2
 Q glutamine           7.1         88          13
 R arginine            6.6         82           3
 S serine              6.1         75           3
 T threonine           4.3         53           2
 V valine              5.7         71           2
 W tryptophan          3.0         37           1
 Y tyrosine            2.7         33           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA-directed DNA polymerase gamma 
POLG                  1.000   DNA-directed DNA polymerase gamma 
MAML2                 0.008   mastermind-like 2 
FRMPD3                0.008   PREDICTED: FERM and PDZ domain containing 3 
FRMPD3                0.008   PREDICTED: FERM and PDZ domain containing 3 
FRMPD3                0.008   PREDICTED: FERM and PDZ domain containing 3 
CREBBP                0.008   CREB binding protein isoform b 
CREBBP                0.008   CREB binding protein isoform a 
ATN1                  0.008   atrophin-1 
ATN1                  0.008   atrophin-1 
MN1                   0.008   meningioma  1 
ZFHX3                 0.007   AT-binding transcription factor 1 
FOXP2                 0.007   forkhead box P2 isoform I 
FOXP2                 0.007   forkhead box P2 isoform III 
FOXP2                 0.007   forkhead box P2 isoform II 
EP400                 0.007   E1A binding protein p400 
THAP11                0.007   THAP domain containing 11 
DENND4B               0.007   DENN/MADD domain containing 4B 
NCOA6                 0.007   nuclear receptor coactivator 6 
NUMBL                 0.007   numb homolog (Drosophila)-like 
C14orf4               0.006   chromosome 14 open reading frame 4 
TBP                   0.006   TATA box binding protein 
SMARCA2               0.006   SWI/SNF-related matrix-associated actin-dependent re...
SMARCA2               0.006   SWI/SNF-related matrix-associated actin-dependent re...
ATXN2                 0.006   ataxin 2 
MED12                 0.006   mediator complex subunit 12 
MAML3                 0.006   mastermind-like 3 
KCNN3                 0.006   small conductance calcium-activated potassium chann...
NFAT5                 0.006   nuclear factor of activated T-cells 5 isoform a [Hom...
NFAT5                 0.006   nuclear factor of activated T-cells 5 isoform c [Homo...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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