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Search of human proteins with 4505723
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens] 811 0.0
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 54 2e-07
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r... 49 8e-06
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 49 1e-05
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 48 1e-05
gi|19224660 protein kinase C and casein kinase substrate in neur... 48 2e-05
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 47 4e-05
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 47 4e-05
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 47 4e-05
gi|24308229 protein kinase C and casein kinase substrate in neur... 47 4e-05
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r... 46 5e-05
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r... 46 5e-05
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r... 46 5e-05
gi|148747351 protein kinase C and casein kinase substrate in neu... 45 9e-05
gi|215422375 neural precursor cell expressed, developmentally do... 45 1e-04
gi|5453680 neural precursor cell expressed, developmentally down... 45 1e-04
gi|78486553 neural precursor cell expressed, developmentally dow... 45 1e-04
gi|166064038 PAK-interacting exchange factor beta isoform a [Hom... 44 2e-04
gi|4505573 PAK-interacting exchange factor beta isoform a [Homo ... 44 2e-04
gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Hom... 43 4e-04
gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Ho... 43 4e-04
gi|5453758 nebulette sarcomeric isoform [Homo sapiens] 43 4e-04
gi|47087157 nebulette non-muscle isoform [Homo sapiens] 43 4e-04
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 43 4e-04
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 43 4e-04
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 43 4e-04
gi|208022687 GTPase regulator associated with the focal adhesion... 43 6e-04
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 42 8e-04
gi|7662208 GTPase regulator associated with the focal adhesion k... 42 8e-04
gi|5453754 NCK adaptor protein 1 [Homo sapiens] 42 0.001
>gi|4505723 peroxisomal biogenesis factor 13 [Homo sapiens]
Length = 403
Score = 811 bits (2094), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MASQPPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPALTRVPPPILPRPS 60
MASQPPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPALTRVPPPILPRPS
Sbjct: 1 MASQPPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPALTRVPPPILPRPS 60
Query: 61 QQTGSSSVNTFRPAYSSFSSGYGAYGNSFYGGYSPYSYGYNGLGYNRLRVDDLPPSRFVQ 120
QQTGSSSVNTFRPAYSSFSSGYGAYGNSFYGGYSPYSYGYNGLGYNRLRVDDLPPSRFVQ
Sbjct: 61 QQTGSSSVNTFRPAYSSFSSGYGAYGNSFYGGYSPYSYGYNGLGYNRLRVDDLPPSRFVQ 120
Query: 121 QAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFS 180
QAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFS
Sbjct: 121 QAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFS 180
Query: 181 AFALVRTIRYLYRRLQRMLGLRRGSENEDLWAESEGTVACLGAEDRAATSAKSWPIFLFF 240
AFALVRTIRYLYRRLQRMLGLRRGSENEDLWAESEGTVACLGAEDRAATSAKSWPIFLFF
Sbjct: 181 AFALVRTIRYLYRRLQRMLGLRRGSENEDLWAESEGTVACLGAEDRAATSAKSWPIFLFF 240
Query: 241 AVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLN 300
AVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLN
Sbjct: 241 AVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLN 300
Query: 301 LALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTL 360
LALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTL
Sbjct: 301 LALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTL 360
Query: 361 TKGATVADSLDEQEAAFESVFVETNKVPVAPDSIGKDGEKQDL 403
TKGATVADSLDEQEAAFESVFVETNKVPVAPDSIGKDGEKQDL
Sbjct: 361 TKGATVADSLDEQEAAFESVFVETNKVPVAPDSIGKDGEKQDL 403
>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
sapiens]
Length = 561
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/59 (49%), Positives = 39/59 (66%), Gaps = 1/59 (1%)
Query: 276 VARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKIL 334
+ARA YD A S +E+SFR GD+L + +E + GW L SL GQ G++PAN VK+L
Sbjct: 9 LARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCLCSLHGQ-QGIVPANRVKLL 66
>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 353
Score = 48.9 bits (115), Expect = 8e-06
Identities = 26/61 (42%), Positives = 42/61 (68%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+V+A+A YD A S +E+SFR GD++ + L++ + GW L SL G+ G++P N++KI
Sbjct: 5 NVLAKALYDNVAESPDELSFRKGDIMTV-LEQDTQGLDGWWLCSLHGR-QGIMPGNHLKI 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 48.5 bits (114), Expect = 1e-05
Identities = 23/55 (41%), Positives = 25/55 (45%)
Query: 5 PPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPALTRVPPPILPRP 59
PPPPP P + GPG GPGP S P P P + PPP PRP
Sbjct: 411 PPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVPCRSTTPPPPPPRP 465
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/67 (31%), Positives = 31/67 (46%), Gaps = 14/67 (20%)
Query: 5 PPPPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRPGQPAL-TRVPPPILPRPSQQT 63
PPPPP+P ++P PG G ++RP P + + PPPI P ++
Sbjct: 459 PPPPPRPPSRPKLPPGKPGVGD-------------VSRPFSPPIHSSSPPPIAPLARAES 505
Query: 64 GSSSVNT 70
SS +T
Sbjct: 506 TSSISST 512
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 48.1 bits (113), Expect = 1e-05
Identities = 26/61 (42%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+V+A+A YD A S +E+SFR GD++ + L++ + GW L SL G+ G++P N +KI
Sbjct: 5 NVLAKALYDNVAESPDELSFRKGDIMTV-LEQDTQGLDGWWLCSLHGR-QGIVPGNRLKI 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|19224660 protein kinase C and casein kinase substrate in neurons
3 [Homo sapiens]
Length = 424
Score = 47.8 bits (112), Expect = 2e-05
Identities = 26/61 (42%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 275 VVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKIL 334
V RA YD+A +E+SFRAG+ L LK + +GW L GL PANYV+ +
Sbjct: 366 VRVRALYDYAGQEADELSFRAGEEL---LKMSEEDEQGWCQGQLQSGRIGLYPANYVECV 422
Query: 335 G 335
G
Sbjct: 423 G 423
>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
sapiens]
Length = 753
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/99 (25%), Positives = 53/99 (53%), Gaps = 5/99 (5%)
Query: 264 SINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTT 323
S++ ++ +V RA+++F +E+E+SF GD++++ E+ GW +L+G+ T
Sbjct: 126 SLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEE----GGWWEGTLNGR-T 180
Query: 324 GLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLTK 362
G P+NYV+ + + + +S + + F + K
Sbjct: 181 GWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINK 219
>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
sapiens]
Length = 803
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/99 (25%), Positives = 53/99 (53%), Gaps = 5/99 (5%)
Query: 264 SINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTT 323
S++ ++ +V RA+++F +E+E+SF GD++++ E+ GW +L+G+ T
Sbjct: 176 SLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEE----GGWWEGTLNGR-T 230
Query: 324 GLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLTK 362
G P+NYV+ + + + +S + + F + K
Sbjct: 231 GWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINK 269
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 46.6 bits (109), Expect = 4e-05
Identities = 25/99 (25%), Positives = 53/99 (53%), Gaps = 5/99 (5%)
Query: 264 SINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTT 323
S++ ++ +V RA+++F +E+E+SF GD++++ E+ GW +L+G+ T
Sbjct: 155 SLDMTDNSNNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEE----GGWWEGTLNGR-T 209
Query: 324 GLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLTK 362
G P+NYV+ + + + +S + + F + K
Sbjct: 210 GWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINK 248
>gi|24308229 protein kinase C and casein kinase substrate in neurons
1 [Homo sapiens]
Length = 444
Score = 46.6 bits (109), Expect = 4e-05
Identities = 27/66 (40%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
Query: 271 EDDH--VVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPA 328
EDD V RA YD+ ++E+SF+AGD L +E + +GW LD GL PA
Sbjct: 382 EDDSKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDE---QGWCRGRLDSGQLGLYPA 438
Query: 329 NYVKIL 334
NYV+ +
Sbjct: 439 NYVEAI 444
>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 232
Score = 46.2 bits (108), Expect = 5e-05
Identities = 25/61 (40%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+V+A+A Y A S +E+SFR GD++ + L++ + GW L SL G+ G++P N++KI
Sbjct: 5 NVLAKALYVNVAESPDELSFRKGDIMTV-LEQDTQGLDGWWLCSLHGR-QGIVPGNHLKI 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 224
Score = 46.2 bits (108), Expect = 5e-05
Identities = 25/61 (40%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+V+A+A Y A S +E+SFR GD++ + L++ + GW L SL G+ G++P N++KI
Sbjct: 5 NVLAKALYVNVAESPDELSFRKGDIMTV-LEQDTQGLDGWWLCSLHGR-QGIVPGNHLKI 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
resistance 1 [Homo sapiens]
Length = 368
Score = 46.2 bits (108), Expect = 5e-05
Identities = 25/61 (40%), Positives = 41/61 (67%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+V+A+A Y A S +E+SFR GD++ + L++ + GW L SL G+ G++P N++KI
Sbjct: 5 NVLAKALYVNVAESPDELSFRKGDIMTV-LEQDTQGLDGWWLCSLHGR-QGIVPGNHLKI 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 45.4 bits (106), Expect = 9e-05
Identities = 24/60 (40%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 275 VVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKIL 334
V RA YD+ +E+SF+AGD L K + +GW LD GL PANYV+ +
Sbjct: 429 VRVRALYDYEGQEHDELSFKAGDELT---KMEDEDEQGWCKGRLDNGQVGLYPANYVEAI 485
>gi|215422375 neural precursor cell expressed, developmentally
down-regulated 9 isoform 3 [Homo sapiens]
Length = 834
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/61 (39%), Positives = 39/61 (63%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+++ARA YD EE++FR GD+L + +++ + GW L SL G+ G++P N VK+
Sbjct: 5 NLMARALYDNVPECAEELAFRKGDILTV-IEQNTGGLEGWWLCSLHGR-QGIVPGNRVKL 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|5453680 neural precursor cell expressed, developmentally
down-regulated 9 isoform 1 [Homo sapiens]
Length = 834
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/61 (39%), Positives = 39/61 (63%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+++ARA YD EE++FR GD+L + +++ + GW L SL G+ G++P N VK+
Sbjct: 5 NLMARALYDNVPECAEELAFRKGDILTV-IEQNTGGLEGWWLCSLHGR-QGIVPGNRVKL 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|78486553 neural precursor cell expressed, developmentally
down-regulated 9 isoform 2 [Homo sapiens]
Length = 174
Score = 45.1 bits (105), Expect = 1e-04
Identities = 24/61 (39%), Positives = 39/61 (63%), Gaps = 2/61 (3%)
Query: 274 HVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
+++ARA YD EE++FR GD+L + +++ + GW L SL G+ G++P N VK+
Sbjct: 5 NLMARALYDNVPECAEELAFRKGDILTV-IEQNTGGLEGWWLCSLHGR-QGIVPGNRVKL 62
Query: 334 L 334
L
Sbjct: 63 L 63
>gi|166064038 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/91 (26%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 272 DDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYV 331
++ +V RA+++F +E+E+SF GD++++ E+ GW +L+G+ TG P+NYV
Sbjct: 6 NNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEE----GGWWEGTLNGR-TGWFPSNYV 60
Query: 332 KILGKRKGRKTVESSKVSKQQQSFTNPTLTK 362
+ + + + +S + + F + K
Sbjct: 61 REVKASEKPVSPKSGTLKSPPKGFDTTAINK 91
>gi|4505573 PAK-interacting exchange factor beta isoform a [Homo
sapiens]
Length = 646
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/91 (26%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 272 DDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYV 331
++ +V RA+++F +E+E+SF GD++++ E+ GW +L+G+ TG P+NYV
Sbjct: 6 NNQLVVRAKFNFQQTNEDELSFSKGDVIHVTRVEE----GGWWEGTLNGR-TGWFPSNYV 60
Query: 332 KILGKRKGRKTVESSKVSKQQQSFTNPTLTK 362
+ + + + +S + + F + K
Sbjct: 61 REVKASEKPVSPKSGTLKSPPKGFDTTAINK 91
>gi|4504111 growth factor receptor-bound protein 2 isoform 1 [Homo
sapiens]
Length = 217
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/57 (38%), Positives = 37/57 (64%), Gaps = 4/57 (7%)
Query: 277 ARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
A A+YDF A +++E+SF+ GD+L + +E + W A L+G+ G IP NY+++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECD---QNWYKAELNGK-DGFIPKNYIEM 55
Score = 30.8 bits (68), Expect = 2.3
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 278 RAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYV 331
+A +DF + E+ FR GD +++ + P W + GQ TG+ P NYV
Sbjct: 162 QALFDFDPQEDGELGFRRGDFIHV-MDNSDP---NWWKGACHGQ-TGMFPRNYV 210
>gi|45359859 growth factor receptor-bound protein 2 isoform 2 [Homo
sapiens]
Length = 176
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/57 (38%), Positives = 37/57 (64%), Gaps = 4/57 (7%)
Query: 277 ARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKI 333
A A+YDF A +++E+SF+ GD+L + +E + W A L+G+ G IP NY+++
Sbjct: 3 AIAKYDFKATADDELSFKRGDILKVLNEECD---QNWYKAELNGK-DGFIPKNYIEM 55
Score = 30.8 bits (68), Expect = 2.3
Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 5/54 (9%)
Query: 278 RAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYV 331
+A +DF + E+ FR GD +++ + P W + GQ TG+ P NYV
Sbjct: 121 QALFDFDPQEDGELGFRRGDFIHV-MDNSDP---NWWKGACHGQ-TGMFPRNYV 169
>gi|5453758 nebulette sarcomeric isoform [Homo sapiens]
Length = 1014
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 5/58 (8%)
Query: 278 RAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQ-TTGLIPANYVKIL 334
RA YD++A E+E+SFR GD + QP GW+ ++ TG++PANY++ +
Sbjct: 960 RAMYDYSAQDEDEVSFRDGDY----IVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 1013
>gi|47087157 nebulette non-muscle isoform [Homo sapiens]
Length = 270
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 5/58 (8%)
Query: 278 RAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQ-TTGLIPANYVKIL 334
RA YD++A E+E+SFR GD + QP GW+ ++ TG++PANY++ +
Sbjct: 216 RAMYDYSAQDEDEVSFRDGDY----IVNVQPIDDGWMYGTVQRTGRTGMLPANYIEFV 269
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 43.1 bits (100), Expect = 4e-04
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 15/84 (17%)
Query: 252 KLLSTHSDEVTDSINWASGEDDHVVAR--AEYDFAAVSEEEISFRAGDMLNLALKEQQPK 309
KLL S+ T + H V + A YD+AA +E+E+SF G ++N+ K+
Sbjct: 1086 KLLGPSSERATPAF--------HPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDP-- 1135
Query: 310 VRGWLLASLDGQTTGLIPANYVKI 333
W ++G TGL P+NYVK+
Sbjct: 1136 --DWWQGEING-VTGLFPSNYVKM 1156
Score = 42.7 bits (99), Expect = 6e-04
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 278 RAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKR 337
RA Y F A + +E+SF +GD++ + E+ GWL S G G P NYV+ +
Sbjct: 736 RALYPFEARNHDEMSFNSGDIIQ--VDEKTVGEPGWLYGSFQG-NFGWFPCNYVEKMPSS 792
Query: 338 KGRKTVESSK------VSKQQQSFTNPTLTKGATVADSLDEQEAAFESVFVETN 385
+ K V K VS S ++ L+ A D Q +F ++ V T+
Sbjct: 793 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQP-ASVTDYQNVSFSNLTVNTS 845
Score = 30.0 bits (66), Expect = 3.9
Identities = 18/67 (26%), Positives = 31/67 (46%)
Query: 276 VARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILG 335
+A+ + A E++S G ++ + K +G L A + G PA++VK+LG
Sbjct: 1030 IAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLG 1089
Query: 336 KRKGRKT 342
R T
Sbjct: 1090 PSSERAT 1096
Score = 28.9 bits (63), Expect = 8.6
Identities = 15/54 (27%), Positives = 30/54 (55%), Gaps = 6/54 (11%)
Query: 279 AEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVK 332
A Y +++V +++F G+ + + K+ + W S+ G +G+ P+NYVK
Sbjct: 961 ALYPYSSVEPGDLTFTEGEEILVTQKDGE-----WWTGSI-GDRSGIFPSNYVK 1008
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 43.1 bits (100), Expect = 4e-04
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 15/84 (17%)
Query: 252 KLLSTHSDEVTDSINWASGEDDHVVAR--AEYDFAAVSEEEISFRAGDMLNLALKEQQPK 309
KLL S+ T + H V + A YD+AA +E+E+SF G ++N+ K+
Sbjct: 1113 KLLGPSSERATPAF--------HPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDP-- 1162
Query: 310 VRGWLLASLDGQTTGLIPANYVKI 333
W ++G TGL P+NYVK+
Sbjct: 1163 --DWWQGEING-VTGLFPSNYVKM 1183
Score = 42.7 bits (99), Expect = 6e-04
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 278 RAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKR 337
RA Y F A + +E+SF +GD++ + E+ GWL S G G P NYV+ +
Sbjct: 763 RALYPFEARNHDEMSFNSGDIIQ--VDEKTVGEPGWLYGSFQG-NFGWFPCNYVEKMPSS 819
Query: 338 KGRKTVESSK------VSKQQQSFTNPTLTKGATVADSLDEQEAAFESVFVETN 385
+ K V K VS S ++ L+ A D Q +F ++ V T+
Sbjct: 820 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQP-ASVTDYQNVSFSNLTVNTS 872
Score = 30.0 bits (66), Expect = 3.9
Identities = 18/67 (26%), Positives = 31/67 (46%)
Query: 276 VARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILG 335
+A+ + A E++S G ++ + K +G L A + G PA++VK+LG
Sbjct: 1057 IAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLG 1116
Query: 336 KRKGRKT 342
R T
Sbjct: 1117 PSSERAT 1123
Score = 28.9 bits (63), Expect = 8.6
Identities = 15/54 (27%), Positives = 30/54 (55%), Gaps = 6/54 (11%)
Query: 279 AEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVK 332
A Y +++V +++F G+ + + K+ + W S+ G +G+ P+NYVK
Sbjct: 988 ALYPYSSVEPGDLTFTEGEEILVTQKDGE-----WWTGSI-GDRSGIFPSNYVK 1035
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 43.1 bits (100), Expect = 4e-04
Identities = 29/84 (34%), Positives = 44/84 (52%), Gaps = 15/84 (17%)
Query: 252 KLLSTHSDEVTDSINWASGEDDHVVAR--AEYDFAAVSEEEISFRAGDMLNLALKEQQPK 309
KLL S+ T + H V + A YD+AA +E+E+SF G ++N+ K+
Sbjct: 1113 KLLGPSSERATPAF--------HPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDP-- 1162
Query: 310 VRGWLLASLDGQTTGLIPANYVKI 333
W ++G TGL P+NYVK+
Sbjct: 1163 --DWWQGEING-VTGLFPSNYVKM 1183
Score = 42.7 bits (99), Expect = 6e-04
Identities = 34/114 (29%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 278 RAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILGKR 337
RA Y F A + +E+SF +GD++ + E+ GWL S G G P NYV+ +
Sbjct: 763 RALYPFEARNHDEMSFNSGDIIQ--VDEKTVGEPGWLYGSFQG-NFGWFPCNYVEKMPSS 819
Query: 338 KGRKTVESSK------VSKQQQSFTNPTLTKGATVADSLDEQEAAFESVFVETN 385
+ K V K VS S ++ L+ A D Q +F ++ V T+
Sbjct: 820 ENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQP-ASVTDYQNVSFSNLTVNTS 872
Score = 30.0 bits (66), Expect = 3.9
Identities = 18/67 (26%), Positives = 31/67 (46%)
Query: 276 VARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKILG 335
+A+ + A E++S G ++ + K +G L A + G PA++VK+LG
Sbjct: 1057 IAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLG 1116
Query: 336 KRKGRKT 342
R T
Sbjct: 1117 PSSERAT 1123
Score = 28.9 bits (63), Expect = 8.6
Identities = 15/54 (27%), Positives = 30/54 (55%), Gaps = 6/54 (11%)
Query: 279 AEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVK 332
A Y +++V +++F G+ + + K+ + W S+ G +G+ P+NYVK
Sbjct: 988 ALYPYSSVEPGDLTFTEGEEILVTQKDGE-----WWTGSI-GDRSGIFPSNYVK 1035
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 42.7 bits (99), Expect = 6e-04
Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 18/102 (17%)
Query: 233 SWPIFLFFAVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEIS 292
SWP+F P ST SD S + A+A Y A + E+S
Sbjct: 676 SWPMF-------SAPSSPMPTSSTSSDSSPVSTPFRK-------AKALYACKAEHDSELS 721
Query: 293 FRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKIL 334
F AG + + Q+P GWL +L+G+T GLIP NYV+ L
Sbjct: 722 FTAGTVFDNVHPSQEP---GWLEGTLNGKT-GLIPENYVEFL 759
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 42.4 bits (98), Expect = 8e-04
Identities = 27/59 (45%), Positives = 28/59 (47%), Gaps = 9/59 (15%)
Query: 5 PPPPPKPWETRRIPGAGPGPGPGPTFQS--ADLGPTLMTRPGQ--PALTRVPPPILPRP 59
PP PP P +PG GP PGP P Q GP PG P LT PPP LP P
Sbjct: 293 PPGPPPP-----VPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGP 346
Score = 32.7 bits (73), Expect = 0.60
Identities = 29/82 (35%), Positives = 33/82 (40%), Gaps = 6/82 (7%)
Query: 5 PPPPPKPWETRRIPGAGPG--PG-PGPTFQSADLGPTLMTRPGQPALTRVPPPILPRPSQ 61
PPPP +T P GP PG PGP L P L P + R PPP+L P Q
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG--DRPPPPVL-FPGQ 282
Query: 62 QTGSSSVNTFRPAYSSFSSGYG 83
G + P GYG
Sbjct: 283 PFGQPPLGPLPPGPPPPVPGYG 304
Score = 29.3 bits (64), Expect = 6.6
Identities = 22/68 (32%), Positives = 26/68 (38%), Gaps = 15/68 (22%)
Query: 5 PPPPPKPWETRRIPGAGP-----------GPGPGPTFQSADLGPTLM---TRPGQPAL-T 49
PPPPP P+ R GP GP PG + + P T G P +
Sbjct: 316 PPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDS 375
Query: 50 RVPPPILP 57
R PPP P
Sbjct: 376 RGPPPTDP 383
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 42.4 bits (98), Expect = 8e-04
Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 4/58 (6%)
Query: 277 ARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVKIL 334
A+A Y A + E+SF AG + + Q+P GWL +L+G+T GLIP NYV+ L
Sbjct: 761 AKALYACKAEHDSELSFTAGTVFDNVHPSQEP---GWLEGTLNGKT-GLIPENYVEFL 814
>gi|5453754 NCK adaptor protein 1 [Homo sapiens]
Length = 377
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 8/97 (8%)
Query: 266 NWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALK-EQQPKVRGWLLASLDGQTTG 324
N +G+ HVV +A Y F++ ++EE++F GD++++ K E P+ W ++G G
Sbjct: 185 NLNTGQVLHVV-QALYPFSSSNDEELNFEKGDVMDVIEKPENDPE--WWKCRKINGM-VG 240
Query: 325 LIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLT 361
L+P NYV ++ + + S Q + P+LT
Sbjct: 241 LVPKNYVTVM---QNNPLTSGLEPSPPQCDYIRPSLT 274
Score = 30.4 bits (67), Expect = 3.0
Identities = 18/75 (24%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 273 DHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLLASLDGQTTGLIPANYVK 332
+ VV A++D+ A E+E+ + + L L + W TG +P+NYV+
Sbjct: 3 EEVVVVAKFDYVAQQEQELDIKKNERLWLL-----DDSKSWWRVRNSMNKTGFVPSNYVE 57
Query: 333 ILGKRKGRKTVESSK 347
+ V++ K
Sbjct: 58 RKNSARKASIVKNLK 72
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,486,356
Number of Sequences: 37866
Number of extensions: 989135
Number of successful extensions: 9159
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 448
Number of HSP's that attempted gapping in prelim test: 6957
Number of HSP's gapped (non-prelim): 2084
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.