Guide to the Human Genome
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Name: GRB2 Sequence: fasta or formatted (176aa) NCBI GI: 45359859
Description:

growth factor receptor-bound protein 2 isoform 2

Referenced in:

Epidermal Growth Factor
Fibroblast Growth Factors
Protein Tyrosine Phosphatases
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [217aa] growth factor receptor-bound protein 2 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.5          8           1
 C cysteine            1.1          2           1
 D aspartate           9.1         16           2
 E glutamate           5.7         10           2
 F phenylalanine       7.4         13           1
 G glycine             6.8         12           1
 H histidine           2.8          5           1
 I isoleucine          4.0          7           1
 K lysine              6.8         12           1
 L leucine             6.2         11           1
 M methionine          2.3          4           1
 N asparagine          7.4         13           1
 P proline             5.1          9           1
 Q glutamine           5.7         10           2
 R arginine            5.1          9           2
 S serine              3.4          6           1
 T threonine           2.8          5           1
 V valine              7.4         13           2
 W tryptophan          2.3          4           2
 Y tyrosine            4.0          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   growth factor receptor-bound protein 2 isoform 2 [Ho... 
GRB2                  0.943   growth factor receptor-bound protein 2 isoform 1 [Hom...
GRAP                  0.523   GRB2-related adaptor protein 
GRAP2                 0.270   GRB2-related adaptor protein 2 
LOC400581             0.190   hypothetical protein LOC400581 
SH3KBP1               0.173   SH3-domain kinase binding protein 1 isoform a 
SORBS1                0.145   sorbin and SH3 domain containing 1 isoform 5 
SORBS1                0.142   sorbin and SH3 domain containing 1 isoform 7 
SORBS1                0.142   sorbin and SH3 domain containing 1 isoform 6 
SORBS1                0.142   sorbin and SH3 domain containing 1 isoform 2 
SORBS1                0.142   sorbin and SH3 domain containing 1 isoform 1 
NCK1                  0.142   NCK adaptor protein 1 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 8 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 7 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 6 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 5 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 4 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 3 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 2 
SORBS2                0.134   sorbin and SH3 domain containing 2 isoform 1 
C1orf113              0.128   SH3 domain-containing protein C1orf113 isoform 1 [H...
STAM                  0.128   signal transducing adaptor molecule 1 
STAM2                 0.119   signal transducing adaptor molecule 2 
ITSN1                 0.116   intersectin 1 isoform ITSN-s 
ITSN1                 0.116   intersectin 1 isoform ITSN-l 
SH3GL3                0.114   SH3-domain GRB2-like 3 
SH3GL2                0.114   SH3-domain GRB2-like 2 
SH3D19                0.114   SH3 domain containing 19 isoform c 
SH3D19                0.114   SH3 domain containing 19 isoform b 
SH3D19                0.114   SH3 domain containing 19 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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