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Search of human proteins with 4505225
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505225 menage a trois 1 (CAK assembly factor) [Homo
sapiens]
(309 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505225 menage a trois 1 (CAK assembly factor) [Homo sapiens] 625 e-179
gi|117938316 tripartite motif-containing 22 [Homo sapiens] 45 8e-05
gi|4505257 moesin [Homo sapiens] 45 1e-04
gi|110347443 TATA element modulatory factor 1 [Homo sapiens] 45 1e-04
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-... 44 2e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 43 3e-04
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 43 3e-04
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 42 0.001
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 42 0.001
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 42 0.001
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 42 0.001
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 42 0.001
gi|22749269 ring finger protein 129 [Homo sapiens] 41 0.001
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 41 0.001
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens] 41 0.001
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi... 41 0.001
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 41 0.001
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 41 0.002
gi|93102364 SWAP-70 protein [Homo sapiens] 40 0.002
gi|148746195 trichohyalin [Homo sapiens] 40 0.002
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.003
gi|221139761 zinc finger protein 853 [Homo sapiens] 39 0.004
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 39 0.004
gi|92859701 myosin VI [Homo sapiens] 39 0.004
gi|88759339 aster-associated protein [Homo sapiens] 39 0.004
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 39 0.006
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 39 0.006
gi|38044112 restin isoform b [Homo sapiens] 39 0.006
gi|4506751 restin isoform a [Homo sapiens] 39 0.006
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 39 0.008
>gi|4505225 menage a trois 1 (CAK assembly factor) [Homo sapiens]
Length = 309
Score = 625 bits (1613), Expect = e-179
Identities = 309/309 (100%), Positives = 309/309 (100%)
Query: 1 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV 60
MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV
Sbjct: 1 MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRV 60
Query: 61 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK 120
QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK
Sbjct: 61 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK 120
Query: 121 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK 180
KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK
Sbjct: 121 KMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK 180
Query: 181 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK 240
QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK
Sbjct: 181 QAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHK 240
Query: 241 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA 300
LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA
Sbjct: 241 LEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDA 300
Query: 301 FSGLFWQPS 309
FSGLFWQPS
Sbjct: 301 FSGLFWQPS 309
>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
Length = 498
Score = 45.1 bits (105), Expect = 8e-05
Identities = 45/177 (25%), Positives = 81/177 (45%), Gaps = 14/177 (7%)
Query: 26 CGHTLCESCV------DLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVL 79
CGH+ C++C+ ++ RG +CP C T + N R V++ E++
Sbjct: 30 CGHSFCQACITAKIKESVIISRGESSCPVCQTRFQPGNLRPNRHLANIVERVKEVKMSPQ 89
Query: 80 KIYNKREEDFPSLREYNDFLEEVEEI---VFNLTNNVDLDNTKKKMEIYQKENKDVIQKN 136
+ KR+ ++ F +E ++ V L+ T + E+ KE ++ +Q
Sbjct: 90 E-GQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGHQTFRINEVV-KECQEKLQVA 147
Query: 137 KLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNK-QAFLDELESSDL 192
+L +E +E E+ + RQE + +IQ E Q+ILK N+ + LD E +L
Sbjct: 148 LQRLIKEDQEAEKLEDDIRQERTAWKNYIQIER--QKILKGFNEMRVILDNEEQREL 202
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/100 (31%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Query: 115 LDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQE-NEQRRLFIQKEEQLQQ 173
L+N KKK E+ +KE K+ I++ K +L +++EE + +QE EQ R ++ E++ ++
Sbjct: 323 LENEKKKREMAEKE-KEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKR 381
Query: 174 ILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLE 213
K A + E+ + ALL A + TQ ++ LE
Sbjct: 382 AQSEAEKLA-KERQEAEEAKEALLQASRDQKKTQEQLALE 420
>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
Length = 1093
Score = 44.7 bits (104), Expect = 1e-04
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 18/201 (8%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLR--EYNDFLEEVEEIVFNLTNNVDL--------DNTK 119
KE + KK +K N +EE L E D L+E +E + L + N
Sbjct: 519 KERDAAKKEIK--NIKEELATRLNSSETADLLKEKDEQIRGLMEEGEKLSKQQLHNSNII 576
Query: 120 KKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKN 179
KK+ KEN++++ K K+ +EEL+ +V + E + + ++L +++R+
Sbjct: 577 KKLRAKDKENENMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQE 636
Query: 180 K-----QAFLDELESSDLPV-ALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHI 233
K Q +DELE + + A L + +K+ + + K + S +K + +
Sbjct: 637 KDLGRLQVDMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEEL 696
Query: 234 SLAPIHKLEEALYEYQPLQIE 254
S A EEA + + L I+
Sbjct: 697 SAALEKAQEEARQQQETLAIQ 717
>gi|169202375 PREDICTED: tripartite motif-containing protein
64B-like [Homo sapiens]
Length = 449
Score = 43.5 bits (101), Expect = 2e-04
Identities = 51/239 (21%), Positives = 88/239 (36%), Gaps = 45/239 (18%)
Query: 26 CGHTLCESCVDLLFVRGAG--NCPECGTPLRKSNFRVQL--------------------- 62
CGH+ C C+ L G CP C K NF L
Sbjct: 30 CGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKPNFNTNLVLKKLSSLARQTRPQNINSSD 89
Query: 63 ----FEDPTVDKEVEIRKKVL----------------KIYNKREEDFPSLREYNDFLEEV 102
+ T + E K++L I EE L + D+L E+
Sbjct: 90 NICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEI 149
Query: 103 EEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRR 162
+ N N K + ++ IQ K+ + ++EE +ER+ E +
Sbjct: 150 NQETRNNLNQETSTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQ 209
Query: 163 LFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEM-QLEKPKPVKP 220
+ ++ Q L+R K + + E+ +P +LL ++ S + ++ Q++KP+PV P
Sbjct: 210 QLQDSQVRMTQHLERM-KDMYRELWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNP 267
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 43.1 bits (100), Expect = 3e-04
Identities = 43/153 (28%), Positives = 67/153 (43%), Gaps = 18/153 (11%)
Query: 64 EDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKME 123
E ++DKE+ +K V E SLRE EE DL +++ E
Sbjct: 960 EKASLDKELMAQKLV----QAEREAQASLREQRAAHEE------------DLQRLQREKE 1003
Query: 124 IYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAF 183
+E + + + +L REQEEL LE E++E + +Q+E +L KQ
Sbjct: 1004 AAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQA 1063
Query: 184 LD--ELESSDLPVALLLAQHKDRSTQLEMQLEK 214
L E E + L L+ +H + LEM+ +K
Sbjct: 1064 LSLKESEKTALSEKLMGTRHSLATISLEMERQK 1096
Score = 33.1 bits (74), Expect = 0.32
Identities = 34/161 (21%), Positives = 73/161 (45%), Gaps = 3/161 (1%)
Query: 127 KENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDE 186
++ +D +++ L+ R+ E +E EV+RQE + R + + + ++ L+R N++
Sbjct: 1167 EDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAV 1226
Query: 187 LESSDLPVALLLAQHKDRSTQLEMQLEKPKPV--KPVTFSTGIKMGQHISLAPIHKLEEA 244
++ ++L LA ++D+ +L + E V + TG++ + L +L+E
Sbjct: 1227 KKAESERISLKLA-NEDKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQEL 1285
Query: 245 LYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAG 285
+ + L E E+ GRL S ++ G
Sbjct: 1286 RRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLG 1326
Score = 32.0 bits (71), Expect = 0.71
Identities = 27/103 (26%), Positives = 53/103 (51%), Gaps = 3/103 (2%)
Query: 116 DNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQIL 175
D + E Q+E + + N+L L+RE+ L +L+V +Q+ E+ R +K + Q+ L
Sbjct: 578 DGAMQAHEDAQREVQRLRSANEL-LSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEEL 636
Query: 176 KRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPV 218
+R+ + L+E + + + + +RS + QLE + V
Sbjct: 637 RRQRDR--LEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSV 677
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 43.1 bits (100), Expect = 3e-04
Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 6/116 (5%)
Query: 101 EVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQ 160
E +I+ L +++ E +KE +D +++ +LK E+E L E +QE E+
Sbjct: 399 EAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER 458
Query: 161 RRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPK 216
+R Q+EE+ +Q + K K E LLL + +++ Q + +EK K
Sbjct: 459 KR---QEEEKKKQEGEEKRKAG---EEAKRKAEEELLLKEKQEQEKQEKAMIEKQK 508
Score = 36.2 bits (82), Expect = 0.038
Identities = 37/149 (24%), Positives = 73/149 (48%), Gaps = 12/149 (8%)
Query: 64 EDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKME 123
E+ + E E RK+ + KR+E+ +E + + EE + L K+K E
Sbjct: 441 EEERLRLEEEARKQEEE--RKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLL---KEKQE 495
Query: 124 IYQKENKDVIQKNKLKLTREQEELEEALEVERQ----ENEQRRLFIQKEEQLQQILKRKN 179
+K+ K +I+K K + E+ E + +ER+ + EQ RL ++++++ +I+KR
Sbjct: 496 -QEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERL--ERKKRIDEIMKRTR 552
Query: 180 KQAFLDELESSDLPVALLLAQHKDRSTQL 208
K +++ D V + A ++ T+L
Sbjct: 553 KSDVPPQVKKEDPKVGVQPAVCVEKKTKL 581
Score = 32.3 bits (72), Expect = 0.55
Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 15/106 (14%)
Query: 130 KDVIQKNK---LKLTREQEELEEALEVERQENEQRRLFI---------QKEEQLQQILKR 177
+ +++K K L+ ++ EE LE +RQ +Q+R + ++EE+L+ +++R
Sbjct: 74 QQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRR 133
Query: 178 ---KNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKP 220
+ +Q L + S P+A+ H + PKP +P
Sbjct: 134 SLERTQQLELKKKYSWGAPLAIGPGGHDACDKLSTSTMSLPKPTEP 179
Score = 31.2 bits (69), Expect = 1.2
Identities = 37/195 (18%), Positives = 84/195 (43%), Gaps = 18/195 (9%)
Query: 100 EEVEEIVFNLTNNVDLDNTKKKM--------EIYQKENKDVIQKNKLKLTREQEELEEAL 151
EE E + + ++ + K+K E +K+ ++ ++ + K +E EE +A
Sbjct: 418 EEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAG 477
Query: 152 EVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQ 211
E +++ E+ L +K+EQ +++ K + E+++ + Q + Q+ +Q
Sbjct: 478 EEAKRKAEEELLLKEKQEQ-----EKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQ 532
Query: 212 LEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPL-----QIETYGPHVPELEML 266
+E+ + + +K + + P K E+ QP + + P+ E+ L
Sbjct: 533 IEQERLERKKRIDEIMKRTRKSDVPPQVKKEDPKVGVQPAVCVEKKTKLVVPNKMEINGL 592
Query: 267 GRLGYLNHVRAASPQ 281
+N V A+P+
Sbjct: 593 NTCQEVNGVDHAAPE 607
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/181 (26%), Positives = 90/181 (49%), Gaps = 24/181 (13%)
Query: 54 RKSNFRVQLFEDPTVDKEV--EIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTN 111
R + + QL + V E+ E+ + L++ + L+E F EV++ T+
Sbjct: 3146 RATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKD----KTD 3201
Query: 112 NVDLDNTKKKMEIYQKENKDV---IQKNKLKL----TREQEELEE---ALEVERQENEQR 161
V L N E QK+++++ ++K K KL R++EELE+ +LE ++Q N Q
Sbjct: 3202 EVHLLNDTLASE--QKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQL 3259
Query: 162 RLFIQKEEQL----QQIL--KRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKP 215
L +++++QL QQ + +R A L E + +L + +LL K R ++ L++
Sbjct: 3260 NLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRE 3319
Query: 216 K 216
+
Sbjct: 3320 R 3320
Score = 33.9 bits (76), Expect = 0.19
Identities = 44/212 (20%), Positives = 97/212 (45%), Gaps = 25/212 (11%)
Query: 67 TVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQ 126
T +++E + +L+ Y K++EDF FL+E + V+ + + ++N+ K+ EI +
Sbjct: 272 THQQQLEEQDHLLEDYQKKKEDFTM---QISFLQEKIK-VYEMEQDKKVENSNKE-EIQE 326
Query: 127 KENKDVIQKNKLKLTREQE---ELEEAL-EVERQENEQRRLFIQKEEQLQQI------LK 176
KE +I++ K+ E++ EL++ L ++ E + +QK ++++ + K
Sbjct: 327 KET--IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSK 384
Query: 177 RKNKQAFLDELESSDLPVALLLAQHKDRSTQLE----MQLEKPKPVKPVTFSTGIKMGQH 232
+K +Q+ + + L HKD + + M+ E + ++ + GQ
Sbjct: 385 QKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQ 444
Query: 233 ISLAPIHKLEEALYEYQPLQIETYGPHVPELE 264
I + +E + ++ E H E+E
Sbjct: 445 I----VQMKQELIRQHMAQMEEMKTRHKGEME 472
Score = 33.5 bits (75), Expect = 0.25
Identities = 37/166 (22%), Positives = 81/166 (48%), Gaps = 15/166 (9%)
Query: 61 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK 120
+L ED ++ + I K + ++ L+ N+ +++E + F N + N +
Sbjct: 639 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ--NEMSQKIETMQFEKDNLITKQN-QL 695
Query: 121 KMEIYQKEN--KDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQ---QIL 175
+EI + ++ + ++ ++T + EL++ +E+ RQE +++ Q+ ++LQ ++L
Sbjct: 696 ILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELL 755
Query: 176 KRKNKQAFLDELESSDLPVALLLAQH---KDRSTQLEMQLEKPKPV 218
+++ K+ D E A L A++ KD LE L+ PV
Sbjct: 756 EKQMKEKENDLQEK----FAQLEAENSILKDEKKTLEDMLKIHTPV 797
Score = 33.5 bits (75), Expect = 0.25
Identities = 29/141 (20%), Positives = 72/141 (51%), Gaps = 16/141 (11%)
Query: 71 EVEIRKKV---LKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQK 127
E+++ ++V +++ ++ + LR+ N LE+ E + + +D ++ +++Q+
Sbjct: 2027 EIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER-DVFQQ 2085
Query: 128 ENKDVIQKNKL---------KLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRK 178
E + + Q+ K+ TRE E+L L +++ ++ + +EQLQ+ ++ +
Sbjct: 2086 EIQKLEQQLKVVPRFQPISEHQTREVEQLANHL---KEKTDKCSELLLSKEQLQRDIQER 2142
Query: 179 NKQAFLDELESSDLPVALLLA 199
N++ E +L ALL++
Sbjct: 2143 NEEIEKLEFRVRELEQALLVS 2163
Score = 33.5 bits (75), Expect = 0.25
Identities = 22/80 (27%), Positives = 45/80 (56%), Gaps = 8/80 (10%)
Query: 122 MEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQ-----RRLFIQKEEQLQQI-- 174
+E+ + +D I + + ++T +E+LE+ E +NE+ +L IQK+E ++
Sbjct: 2187 LEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQE 2246
Query: 175 LKRKNKQAFLDELESSDLPV 194
L+++NK F D++E L +
Sbjct: 2247 LEQENK-LFKDDMEKLGLAI 2265
Score = 32.7 bits (73), Expect = 0.42
Identities = 19/55 (34%), Positives = 37/55 (67%), Gaps = 3/55 (5%)
Query: 129 NKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKE--EQLQQILKRKNKQ 181
N++ ++ + +L R+ +E ++A E+ RQ + R++ Q+E EQLQ+ +KR N+Q
Sbjct: 1583 NEEQLEDMRQELVRQYQEHQQATELLRQAH-MRQMERQREDQEQLQEEIKRLNRQ 1636
Score = 32.7 bits (73), Expect = 0.42
Identities = 23/97 (23%), Positives = 52/97 (53%), Gaps = 8/97 (8%)
Query: 124 IYQKENKDVIQKNKLKLTREQEELEEALE--VERQENEQRRLFIQKEEQLQ---QILKRK 178
I +KE ++ +KN L+ ++ EL++ LE ++Q ++++ Q E L+ ++
Sbjct: 2623 ILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSN 2682
Query: 179 NKQAFLDELE---SSDLPVALLLAQHKDRSTQLEMQL 212
+ F +ELE + + LA +K+++ +L+ +L
Sbjct: 2683 EESGFFNELEALRAESVATKAELASYKEKAEKLQEEL 2719
Score = 30.0 bits (66), Expect = 2.7
Identities = 32/143 (22%), Positives = 66/143 (46%), Gaps = 21/143 (14%)
Query: 92 LREYNDFLEEVEEIVFNLTNNVD---LDN--TKKKMEIYQKENKDVIQ----------KN 136
L+E LEE + L N + LD+ T+++ME ++ ++ +Q K
Sbjct: 3345 LKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK 3404
Query: 137 KLKLTREQEELEEALEVERQE------NEQRRLFIQKEEQLQQILKRKNKQAFLDELESS 190
+L + E+L+ LE +RQ+ QR I +E Q Q++ + + +++ ++
Sbjct: 3405 MHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNL 3464
Query: 191 DLPVALLLAQHKDRSTQLEMQLE 213
+ P L + R+ L+ ++E
Sbjct: 3465 NEPTTWSLTSDRTRNWVLQQKIE 3487
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 41.6 bits (96), Expect = 0.001
Identities = 48/181 (26%), Positives = 90/181 (49%), Gaps = 24/181 (13%)
Query: 54 RKSNFRVQLFEDPTVDKEV--EIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTN 111
R + + QL + V E+ E+ + L++ + L+E F EV++ T+
Sbjct: 3138 RATELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKD----KTD 3193
Query: 112 NVDLDNTKKKMEIYQKENKDV---IQKNKLKL----TREQEELEE---ALEVERQENEQR 161
V L N E QK+++++ ++K K KL R++EELE+ +LE ++Q N Q
Sbjct: 3194 EVHLLNDTLASE--QKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQL 3251
Query: 162 RLFIQKEEQL----QQIL--KRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKP 215
L +++++QL QQ + +R A L E + +L + +LL K R ++ L++
Sbjct: 3252 NLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRE 3311
Query: 216 K 216
+
Sbjct: 3312 R 3312
Score = 35.4 bits (80), Expect = 0.065
Identities = 31/135 (22%), Positives = 68/135 (50%), Gaps = 18/135 (13%)
Query: 77 KVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK----------KMEIYQ 126
K ++ +E+ ++E N+ +E++E V L + +++ K +E+
Sbjct: 2124 KCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQL 2183
Query: 127 KENKDVIQKNKLKLTREQEELEEALEVERQENEQ-----RRLFIQKEEQLQQI--LKRKN 179
+ +D I + + ++T +E+LE+ E +NE+ +L IQK+E ++ L+++N
Sbjct: 2184 QAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQEN 2243
Query: 180 KQAFLDELESSDLPV 194
K F D++E L +
Sbjct: 2244 K-LFKDDMEKLGLAI 2257
Score = 35.0 bits (79), Expect = 0.084
Identities = 33/165 (20%), Positives = 81/165 (49%), Gaps = 25/165 (15%)
Query: 71 EVEIRKKV---LKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQK 127
E+++ ++V +++ ++ + LR+ N LE+ E + + +D ++ +++Q+
Sbjct: 2027 EIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER-DVFQQ 2085
Query: 128 ENKDVIQKNKL---------KLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRK 178
E + + Q+ K+ TRE E+L L +++ ++ + +EQLQ+ ++ +
Sbjct: 2086 EIQKLEQQLKVVPRFQPISEHQTREVEQLANHL---KEKTDKCSELLLSKEQLQRDIQER 2142
Query: 179 NKQAFLDELESSDLPVALLLAQHK---------DRSTQLEMQLEK 214
N++ E +L ALL+ K + S ++++Q E+
Sbjct: 2143 NEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAER 2187
Score = 33.9 bits (76), Expect = 0.19
Identities = 44/212 (20%), Positives = 97/212 (45%), Gaps = 25/212 (11%)
Query: 67 TVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQ 126
T +++E + +L+ Y K++EDF FL+E + V+ + + ++N+ K+ EI +
Sbjct: 272 THQQQLEEQDHLLEDYQKKKEDFTM---QISFLQEKIK-VYEMEQDKKVENSNKE-EIQE 326
Query: 127 KENKDVIQKNKLKLTREQE---ELEEAL-EVERQENEQRRLFIQKEEQLQQI------LK 176
KE +I++ K+ E++ EL++ L ++ E + +QK ++++ + K
Sbjct: 327 KET--IIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSK 384
Query: 177 RKNKQAFLDELESSDLPVALLLAQHKDRSTQLE----MQLEKPKPVKPVTFSTGIKMGQH 232
+K +Q+ + + L HKD + + M+ E + ++ + GQ
Sbjct: 385 QKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQ 444
Query: 233 ISLAPIHKLEEALYEYQPLQIETYGPHVPELE 264
I + +E + ++ E H E+E
Sbjct: 445 I----VQMKQELIRQHMAQMEEMKTRHKGEME 472
Score = 33.5 bits (75), Expect = 0.25
Identities = 37/166 (22%), Positives = 81/166 (48%), Gaps = 15/166 (9%)
Query: 61 QLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKK 120
+L ED ++ + I K + ++ L+ N+ +++E + F N + N +
Sbjct: 639 KLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQ--NEMSQKIETMQFEKDNLITKQN-QL 695
Query: 121 KMEIYQKEN--KDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQ---QIL 175
+EI + ++ + ++ ++T + EL++ +E+ RQE +++ Q+ ++LQ ++L
Sbjct: 696 ILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELL 755
Query: 176 KRKNKQAFLDELESSDLPVALLLAQH---KDRSTQLEMQLEKPKPV 218
+++ K+ D E A L A++ KD LE L+ PV
Sbjct: 756 EKQMKEKENDLQEK----FAQLEAENSILKDEKKTLEDMLKIHTPV 797
Score = 32.7 bits (73), Expect = 0.42
Identities = 19/55 (34%), Positives = 37/55 (67%), Gaps = 3/55 (5%)
Query: 129 NKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKE--EQLQQILKRKNKQ 181
N++ ++ + +L R+ +E ++A E+ RQ + R++ Q+E EQLQ+ +KR N+Q
Sbjct: 1583 NEEQLEDMRQELVRQYQEHQQATELLRQAH-MRQMERQREDQEQLQEEIKRLNRQ 1636
Score = 32.7 bits (73), Expect = 0.42
Identities = 23/97 (23%), Positives = 52/97 (53%), Gaps = 8/97 (8%)
Query: 124 IYQKENKDVIQKNKLKLTREQEELEEALE--VERQENEQRRLFIQKEEQLQ---QILKRK 178
I +KE ++ +KN L+ ++ EL++ LE ++Q ++++ Q E L+ ++
Sbjct: 2615 ILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSN 2674
Query: 179 NKQAFLDELE---SSDLPVALLLAQHKDRSTQLEMQL 212
+ F +ELE + + LA +K+++ +L+ +L
Sbjct: 2675 EESGFFNELEALRAESVATKAELASYKEKAEKLQEEL 2711
Score = 30.0 bits (66), Expect = 2.7
Identities = 32/143 (22%), Positives = 66/143 (46%), Gaps = 21/143 (14%)
Query: 92 LREYNDFLEEVEEIVFNLTNNVD---LDN--TKKKMEIYQKENKDVIQ----------KN 136
L+E LEE + L N + LD+ T+++ME ++ ++ +Q K
Sbjct: 3337 LKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKK 3396
Query: 137 KLKLTREQEELEEALEVERQE------NEQRRLFIQKEEQLQQILKRKNKQAFLDELESS 190
+L + E+L+ LE +RQ+ QR I +E Q Q++ + + +++ ++
Sbjct: 3397 MHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQNL 3456
Query: 191 DLPVALLLAQHKDRSTQLEMQLE 213
+ P L + R+ L+ ++E
Sbjct: 3457 NEPTTWSLTSDRTRNWVLQQKIE 3479
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 41.6 bits (96), Expect = 0.001
Identities = 55/233 (23%), Positives = 101/233 (43%), Gaps = 42/233 (18%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKK-MEIYQKE 128
K+++ L Y K +E+ P + F E+ + + N++L+ ++ ME Q+E
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKKLPVTF-EDKRKANYE-RGNMELEKRRQALMEQQQRE 392
Query: 129 NKDVIQKNKLKLTREQEELEEA---------------LEVERQENEQRRLFIQKEEQLQQ 173
+ QK K + R+Q EL+E E+ERQ E+RR I++ E +Q
Sbjct: 393 AERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQ 452
Query: 174 ILKRK--------NKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPV------- 218
L+R+ +Q L++ + L ++ K+ +LE K + +
Sbjct: 453 ELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDV 512
Query: 219 --KPVTFSTGIKMGQ---HISLAPIHKLEEALYEYQPLQIETYGPHVPELEML 266
K T T +++ + + I +L++ L EYQ I VPE ++L
Sbjct: 513 RLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYL----VPEKQLL 561
Score = 30.4 bits (67), Expect = 2.1
Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 11/112 (9%)
Query: 76 KKVLKIYNKREEDFPSLREYN-DFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQ 134
K++ + YN ++ L + D L+E+E L L++ + K+ K+ +
Sbjct: 621 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKA---KQGKENLW 677
Query: 135 KNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDE 186
K L+ +E+EE ++ L+ E+ + + IQ+EE+ + +RK+K E
Sbjct: 678 KENLR--KEEEEKQKRLQEEKTQEK-----IQEEERKAEEKQRKDKDTLKAE 722
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 41.6 bits (96), Expect = 0.001
Identities = 55/233 (23%), Positives = 101/233 (43%), Gaps = 42/233 (18%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKK-MEIYQKE 128
K+++ L Y K +E+ P + F E+ + + N++L+ ++ ME Q+E
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKKLPVTF-EDKRKANYE-RGNMELEKRRQALMEQQQRE 392
Query: 129 NKDVIQKNKLKLTREQEELEEA---------------LEVERQENEQRRLFIQKEEQLQQ 173
+ QK K + R+Q EL+E E+ERQ E+RR I++ E +Q
Sbjct: 393 AERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQ 452
Query: 174 ILKRK--------NKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPV------- 218
L+R+ +Q L++ + L ++ K+ +LE K + +
Sbjct: 453 ELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDV 512
Query: 219 --KPVTFSTGIKMGQ---HISLAPIHKLEEALYEYQPLQIETYGPHVPELEML 266
K T T +++ + + I +L++ L EYQ I VPE ++L
Sbjct: 513 RLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYL----VPEKQLL 561
Score = 30.4 bits (67), Expect = 2.1
Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 11/112 (9%)
Query: 76 KKVLKIYNKREEDFPSLREYN-DFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQ 134
K++ + YN ++ L + D L+E+E L L++ + K+ K+ +
Sbjct: 648 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKA---KQGKENLW 704
Query: 135 KNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDE 186
K L+ +E+EE ++ L+ E+ + + IQ+EE+ + +RK+K E
Sbjct: 705 KENLR--KEEEEKQKRLQEEKTQEK-----IQEEERKAEEKQRKDKDTLKAE 749
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 41.6 bits (96), Expect = 0.001
Identities = 55/233 (23%), Positives = 101/233 (43%), Gaps = 42/233 (18%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKK-MEIYQKE 128
K+++ L Y K +E+ P + F E+ + + N++L+ ++ ME Q+E
Sbjct: 335 KQIDSINGTLPSYQKMQEEEPQKKLPVTF-EDKRKANYE-RGNMELEKRRQALMEQQQRE 392
Query: 129 NKDVIQKNKLKLTREQEELEEA---------------LEVERQENEQRRLFIQKEEQLQQ 173
+ QK K + R+Q EL+E E+ERQ E+RR I++ E +Q
Sbjct: 393 AERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQ 452
Query: 174 ILKRK--------NKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPV------- 218
L+R+ +Q L++ + L ++ K+ +LE K + +
Sbjct: 453 ELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDV 512
Query: 219 --KPVTFSTGIKMGQ---HISLAPIHKLEEALYEYQPLQIETYGPHVPELEML 266
K T T +++ + + I +L++ L EYQ I VPE ++L
Sbjct: 513 RLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQEYQNKLIYL----VPEKQLL 561
Score = 30.4 bits (67), Expect = 2.1
Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 11/112 (9%)
Query: 76 KKVLKIYNKREEDFPSLREYN-DFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQ 134
K++ + YN ++ L + D L+E+E L L++ + K+ K+ +
Sbjct: 648 KELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKKLEDEAARKA---KQGKENLW 704
Query: 135 KNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDE 186
K L+ +E+EE ++ L+ E+ + + IQ+EE+ + +RK+K E
Sbjct: 705 KENLR--KEEEEKQKRLQEEKTQEK-----IQEEERKAEEKQRKDKDTLKAE 749
>gi|22749269 ring finger protein 129 [Homo sapiens]
Length = 471
Score = 41.2 bits (95), Expect = 0.001
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 46/247 (18%)
Query: 2 DDQGCPRCKTTKYRNPSLKLMVNV-CGHTLCESCVDLLF--VRGAGNCPECGTPLRKSNF 58
++ CP C +Y LK V + CGH C SC+ + + + CP C +F
Sbjct: 12 EESSCPIC--LEY----LKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYKSF 65
Query: 59 R--VQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFL-----EEVE----EIVF 107
R QL + K+++IR+ KR+++ ++N FL +++E + F
Sbjct: 66 RRNPQLRNLTEIAKQLQIRRS----KRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCSF 121
Query: 108 NLTNNVDLDNTKKKMEIYQKE-----------NKDVIQKNKLKLTREQEELEEALEVERQ 156
+ + KK Y +E N + ++K + + EL++ +E +R+
Sbjct: 122 STKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKRE 181
Query: 157 ----ENEQRRLFIQKEEQ--LQQIL-KRKNKQAFLDE--LESSDLPVAL--LLAQHKDRS 205
E EQ RLF+Q E++ L+QI + N A L+E +E SD L LL + + +S
Sbjct: 182 EINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKS 241
Query: 206 TQLEMQL 212
Q ++L
Sbjct: 242 VQSNLEL 248
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/148 (21%), Positives = 76/148 (51%), Gaps = 13/148 (8%)
Query: 85 REEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQ 144
++E S + + +EE+E+ V L + ++K ++ +ENK ++K+ LK E+
Sbjct: 492 KQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEK 551
Query: 145 E--ELEEALEVERQENEQR-----RLFIQKEEQLQQI-----LKRKNKQAFLDELESS-D 191
+ +L+ L+ +++ +++ +KEEQL ++ L+ + A L+E + +
Sbjct: 552 KAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVE 611
Query: 192 LPVALLLAQHKDRSTQLEMQLEKPKPVK 219
L + A+ K++ ++E L + K ++
Sbjct: 612 LNSEKVYAEMKEQMEKVEADLTRSKSLR 639
Score = 36.6 bits (83), Expect = 0.029
Identities = 46/203 (22%), Positives = 88/203 (43%), Gaps = 36/203 (17%)
Query: 84 KREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNK-----L 138
KR+ + S + Y + E++E++ +LT + L + K ++Q E D+ Q+ + L
Sbjct: 607 KRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLE--DIRQRYEQQIVEL 664
Query: 139 KLTREQEEL---------------EEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAF 183
KL EQE+ + E+E E + R ++ E Q+Q+ K+++ Q
Sbjct: 665 KLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQE-FKKRDAQVI 723
Query: 184 LD-ELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLE 242
D E + L L+ + + +E+ L + + + T I ++KL+
Sbjct: 724 ADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEI---------VVNKLK 774
Query: 243 EALYEYQPLQIETYGPHVPELEM 265
E + ++IE H E EM
Sbjct: 775 A---ESEKMKIELKKTHAAETEM 794
Score = 30.0 bits (66), Expect = 2.7
Identities = 45/205 (21%), Positives = 80/205 (39%), Gaps = 57/205 (27%)
Query: 83 NKREEDFPS-LREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLT 141
NK E ++ + + N ++E+E V LT + N +++ KL
Sbjct: 393 NKMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQ-----------------KLI 435
Query: 142 REQEELEEALEV---ERQENEQRRLFIQKE--------EQLQQILKRK------------ 178
+E+ ELE ++ E QE + RR + KE EQ ++L+ K
Sbjct: 436 QEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEH 495
Query: 179 -----NKQAFLDELESSDLPVALLLA--------QHKDRSTQLEMQLEKPKPV---KPVT 222
+ ++ELE + + L Q +D+ + +M+ K + K
Sbjct: 496 ALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHD 555
Query: 223 FSTGIKMGQHISLAPIHKLEEALYE 247
+ + G+ + IHK EEAL E
Sbjct: 556 LQSELDKGKEDTQKKIHKFEEALKE 580
>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
Length = 757
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/201 (18%), Positives = 87/201 (43%), Gaps = 11/201 (5%)
Query: 48 ECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVF 107
E PLRK +Q+ ++ ++ + ++ ++ EED + Y++ + +
Sbjct: 189 ELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEED---RKNYSEVQIRCQRLAL 245
Query: 108 NLTNNVDL-DNTKKKMEIYQK--ENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLF 164
L + L + E Y K +D +++ ++L R+ E LE + ++ +E +
Sbjct: 246 ELADTKQLIQQGDYRQENYDKVKSERDALEQEVIELRRKHEILEASHMIQTKERSELSKE 305
Query: 165 IQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFS 224
+ EQ +L++ + L ++ +++ A +DR +L+ QLE+ K + +
Sbjct: 306 VVTLEQTVTLLQKDKEY-----LNRQNMELSVRCAHEEDRLERLQAQLEESKKAREEMYE 360
Query: 225 TGIKMGQHISLAPIHKLEEAL 245
+ H +KL + L
Sbjct: 361 KYVASRDHYKTEYENKLHDEL 381
>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
sapiens]
Length = 481
Score = 41.2 bits (95), Expect = 0.001
Identities = 52/228 (22%), Positives = 103/228 (45%), Gaps = 34/228 (14%)
Query: 2 DDQGCPRCKTTKYRNPSLKLMVNV-CGHTLCESCVDLLF------VRGAGNCPECGTPLR 54
D+ CP C+ T L+ V + CGH C +C+ + + CP C P R
Sbjct: 12 DEVNCPICQGT------LREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFR 65
Query: 55 KSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFL------EEVEEIVFN 108
+FR ++ V + +E R +++ EED +E+ + + +E++ V
Sbjct: 66 PGSFRPN-WQLANVVENIE-RLQLVSTLGLGEEDV--CQEHGEKIYFFCEDDEMQLCVVC 121
Query: 109 LTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRR-LFIQK 167
+T + +E ++ I K L +E+EE++ E++ +EN++ + L Q
Sbjct: 122 REAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQ---EIQSRENKRMQVLLTQV 178
Query: 168 EEQLQQILKR-KNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEK 214
+ QQ++ + + FL+E +S +LLAQ + + + Q ++
Sbjct: 179 STKRQQVISEFAHLRKFLEEQQS------ILLAQLESQDGDILRQRDE 220
>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo
sapiens]
Length = 395
Score = 41.2 bits (95), Expect = 0.001
Identities = 52/228 (22%), Positives = 103/228 (45%), Gaps = 34/228 (14%)
Query: 2 DDQGCPRCKTTKYRNPSLKLMVNV-CGHTLCESCVDLLF------VRGAGNCPECGTPLR 54
D+ CP C+ T L+ V + CGH C +C+ + + CP C P R
Sbjct: 12 DEVNCPICQGT------LREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFR 65
Query: 55 KSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFL------EEVEEIVFN 108
+FR ++ V + +E R +++ EED +E+ + + +E++ V
Sbjct: 66 PGSFRPN-WQLANVVENIE-RLQLVSTLGLGEEDV--CQEHGEKIYFFCEDDEMQLCVVC 121
Query: 109 LTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRR-LFIQK 167
+T + +E ++ I K L +E+EE++ E++ +EN++ + L Q
Sbjct: 122 REAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQ---EIQSRENKRMQVLLTQV 178
Query: 168 EEQLQQILKR-KNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEK 214
+ QQ++ + + FL+E +S +LLAQ + + + Q ++
Sbjct: 179 STKRQQVISEFAHLRKFLEEQQS------ILLAQLESQDGDILRQRDE 220
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/167 (23%), Positives = 80/167 (47%), Gaps = 33/167 (19%)
Query: 70 KEVE-IRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVD-------------- 114
KEV+ + ++LK+ N EE + ++E + NLTN V
Sbjct: 1484 KEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKK 1543
Query: 115 -LDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEA-LEVERQENEQRRLFIQKEEQLQ 172
++ K ++++ +E + +++N+ K+ Q EL EA E+ER+ +E K+E+++
Sbjct: 1544 LIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELERKLSE-------KDEEIE 1596
Query: 173 QILKRKNKQAFLDELES-------SDLPVALLLAQHKDRSTQLEMQL 212
R+ +Q +D L+S S + V L + ++ ++E+QL
Sbjct: 1597 NF--RRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQL 1641
Score = 35.0 bits (79), Expect = 0.084
Identities = 47/179 (26%), Positives = 80/179 (44%), Gaps = 36/179 (20%)
Query: 68 VDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEV-----------EEIVFNLTNNVDLD 116
V++E EI ++ K E++ L++ D LE + E V NLT V+
Sbjct: 938 VEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFL 997
Query: 117 N---------TKKKMEIYQKENKDV---------IQKNKLKLTREQEELEEALEVERQEN 158
N K E +Q+ D+ + K LKL ++ +ELE ALE ER
Sbjct: 998 NEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQER--- 1054
Query: 159 EQRRLFIQKE-EQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPK 216
+ R+ ++E +L+ LK + ++ LESS +A L + + +Q+ ++E K
Sbjct: 1055 -KARMNCERELHKLEGNLKLNRES--MENLESSQRHLAEELRKKELELSQMNSKVENEK 1110
Score = 31.2 bits (69), Expect = 1.2
Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 33/151 (21%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYND---------FLEEVEEIVFNLTNNVDLDNTKK 120
++V + ++ + ED SL+E + LE E I T N L + KK
Sbjct: 1681 EQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKK 1740
Query: 121 KMEI----YQKENKDVIQ----------KNKLKLTREQEELEEA------LEVERQENEQ 160
K+E QKE ++V+Q K ++ EEL++ LE R+ EQ
Sbjct: 1741 KLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQ 1800
Query: 161 RRLFIQKE--EQLQQILKRKNKQAFLDELES 189
+QK E Q L KQ + +LES
Sbjct: 1801 TITDLQKRLAEAEQMALMGSRKQ--IQKLES 1829
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 40.4 bits (93), Expect = 0.002
Identities = 35/165 (21%), Positives = 76/165 (46%), Gaps = 13/165 (7%)
Query: 55 KSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVD 114
++ F +L + + +++E ++V + ++ E+ +RE D +++E + +
Sbjct: 384 QARFSTELEREKLIRQQME--EQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQ 441
Query: 115 LDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQI 174
+ T +K++ E + + K EQ++ + E E+QE E Q++
Sbjct: 442 DEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELEN-----------QRV 490
Query: 175 LKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVK 219
LK + Q +++LE +L L Q+++ +LEM K K K
Sbjct: 491 LKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWK 535
Score = 29.6 bits (65), Expect = 3.5
Identities = 26/104 (25%), Positives = 55/104 (52%), Gaps = 11/104 (10%)
Query: 127 KENKDVIQKNKL----KLTREQEELEEALEVERQENEQRRLFIQK------EEQLQQILK 176
++ + ++K +L +L R+ +EL+ A E ++QE E R +++ EE+ +++
Sbjct: 320 RQRRKELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQT 379
Query: 177 RKNKQA-FLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVK 219
+ QA F ELE L + Q +S++LE L++ + ++
Sbjct: 380 QVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELE 423
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.4 bits (93), Expect = 0.002
Identities = 43/193 (22%), Positives = 91/193 (47%), Gaps = 17/193 (8%)
Query: 71 EVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENK 130
E E R++ LK + D+ RE E E L + + + ++ +++ ++E +
Sbjct: 439 EQERREQRLKREQEERRDWLK-REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 131 DVIQKNKLKLTREQEELEEALEVERQENEQR---------RLFIQKEEQLQQILKRKNKQ 181
+ ++ + +L REQEE E ++RQE E+R +L ++EE+ +Q+LKR+ ++
Sbjct: 498 EQQERREQQLRREQEERREQ-RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 182 AFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKL 241
E L + ++R QL ++ E+ + + + ++ Q + + +L
Sbjct: 557 RLEQERREQRLK-----REQEERRDQL-LKREEERRQQRLKREQEERLEQRLKREEVERL 610
Query: 242 EEALYEYQPLQIE 254
E+ Q L+ E
Sbjct: 611 EQEERREQRLKRE 623
Score = 39.7 bits (91), Expect = 0.003
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 17/135 (12%)
Query: 69 DKEVEIRKKVLKIYNKREEDFPSLREYN-------------DFLEEVEEIVFNLTNNVDL 115
D+E E R++ LK+ + + RE EE E + L + L
Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538
Query: 116 --DNTKKKMEIYQKENKDVIQKNKL--KLTREQEELEEALEVERQENEQRRLFIQKEEQL 171
+ +++ ++ ++E + +++ + +L REQEE + L +E Q+RL ++EE+L
Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598
Query: 172 QQILKRKNKQAFLDE 186
+Q LKR+ + E
Sbjct: 599 EQRLKREEVERLEQE 613
Score = 38.1 bits (87), Expect = 0.010
Identities = 33/128 (25%), Positives = 61/128 (47%), Gaps = 25/128 (19%)
Query: 84 KREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTRE 143
+R+E RE + +E E+++ ++++E +E ++V Q+ + +L RE
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREEREK----RRRQELERQYREEEEVQQEEE-QLLRE 1156
Query: 144 QEELEEALEVERQENEQRRLFIQKEEQL-------------------QQILKRKNKQAFL 184
+ E E+ERQ E+ L Q+EEQL +++ ++K KQ +
Sbjct: 1157 EPEKRRRQELERQYREEEEL-QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 185 DELESSDL 192
DE + SDL
Sbjct: 1216 DEDQRSDL 1223
Score = 35.4 bits (80), Expect = 0.065
Identities = 34/138 (24%), Positives = 65/138 (47%), Gaps = 21/138 (15%)
Query: 84 KREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKE--NKDVIQKNKLKLT 141
+R+E RE + +E E+++ + K++ + ++++ KD +Q+ + +L
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLRE-------EREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 142 REQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQH 201
RE+ E E ERQ E+ L Q+EE +Q+L + + ELE +
Sbjct: 1035 REEREKRRLQERERQYREEEEL--QQEE--EQLLGEERETRRRQELERQ--------YRK 1082
Query: 202 KDRSTQLEMQLEKPKPVK 219
++ Q E QL + +P K
Sbjct: 1083 EEELQQEEEQLLREEPEK 1100
Score = 35.0 bits (79), Expect = 0.084
Identities = 28/118 (23%), Positives = 61/118 (51%), Gaps = 16/118 (13%)
Query: 65 DPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEI 124
D + +E E R++ LK + + RE + LE+ E +++ +
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEE---------------RREQRL 620
Query: 125 YQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQ-LQQILKRKNKQ 181
++E ++ ++ LK ++E ++ L E+QE ++RL ++EE+ L+Q LKR++++
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE 678
Score = 33.9 bits (76), Expect = 0.19
Identities = 38/187 (20%), Positives = 89/187 (47%), Gaps = 20/187 (10%)
Query: 69 DKEVEIRKKVL-KIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQK 127
+KE R+ VL K K +E+ P + + EE E++ ++ +++ + ++
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEP--QRQRELQEEEEQL-----RKLERQELRRERQEEEQ 295
Query: 128 ENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDEL 187
+ + + ++ +L+ +E+E E+ + ER+E ++RR Q+EE+ +Q L+R+ ++ +L
Sbjct: 296 QQQRLRREQQLRRKQEEERREQ--QEERREQQERR--EQQEERREQQLRREQEERREQQL 351
Query: 188 ESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYE 247
+ + R QL + E+ + + + ++ Q + + E+ L
Sbjct: 352 RREQ--------EEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRR 403
Query: 248 YQPLQIE 254
Q L+ E
Sbjct: 404 EQQLRRE 410
Score = 33.9 bits (76), Expect = 0.19
Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 92 LREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEAL 151
LR+ L+E EE + + + +++ + Q ++ +Q+ + +L RE+ E
Sbjct: 899 LRKEQQLLQEEEEEL----QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 152 EVERQENEQRRLFIQKEEQL-----QQILKRKNKQAFLDELESSDLPVALLLAQHKDRST 206
E ERQ + ++L QKEEQL ++ +++ ++ + +E E LL + + R
Sbjct: 955 ERERQYRKDKKL-QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 207 Q 207
Q
Sbjct: 1014 Q 1014
Score = 33.5 bits (75), Expect = 0.25
Identities = 35/163 (21%), Positives = 77/163 (47%), Gaps = 15/163 (9%)
Query: 68 VDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTN-NVDLDNTKKKMEIYQ 126
+++E ++R++ + + + D RE L+E EE + ++++ +
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRD-RKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 127 KENKDVIQKNKLKLT------REQEELEEALEVERQENEQRRLFIQKEEQL------QQI 174
+E K + ++ +L+ RE+E+L + E E+ ++R I +EEQL QQ+
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764
Query: 175 LKRKNKQAFLDELE-SSDLPVALLLAQHKDRSTQLEMQLEKPK 216
+++ + F +E + + L +Q DR + E QL + +
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
Score = 32.7 bits (73), Expect = 0.42
Identities = 41/157 (26%), Positives = 70/157 (44%), Gaps = 28/157 (17%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNN-----VDLDNTKKKMEI 124
++ E R++ LK + E LR E EE L ++ + +++++
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 125 YQKENKDVI-----QKNKLKLTREQEE-LEEAL---EVERQENEQRRLFIQKEEQLQQIL 175
Q+E +D + ++ + +L REQEE LE+ L EVER E E+RR +Q L
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR---------EQRL 620
Query: 176 KR-----KNKQAFLDELESSDLPVALLLAQHKDRSTQ 207
KR + +Q L E + L + ++R Q
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Score = 32.7 bits (73), Expect = 0.42
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 10/99 (10%)
Query: 84 KREEDFPSLREYNDFLEEVEEIVFNLTNNVDL--------DNTKKKMEIYQKEN-KDVIQ 134
+R E L+E D L+E +E + D + +++ +Y K ++ ++
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR 900
Query: 135 KNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQ 173
K + L E+EEL+ +R+ EQ R + ++EEQLQQ
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQY-REEEQLQQ 938
Score = 32.7 bits (73), Expect = 0.42
Identities = 30/105 (28%), Positives = 54/105 (51%), Gaps = 17/105 (16%)
Query: 118 TKKKMEI---YQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQI 174
T+++ E+ Y+KE + +Q+ + +L RE+ E E ERQ E+ L Q+EE +Q+
Sbjct: 1070 TRRRQELERQYRKEEE--LQQEEEQLLREEPEKRRRQERERQCREEEEL--QQEE--EQL 1123
Query: 175 LKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVK 219
L+ + ++ ELE + ++ Q E QL + +P K
Sbjct: 1124 LREEREKRRRQELERQ--------YREEEEVQQEEEQLLREEPEK 1160
Score = 32.7 bits (73), Expect = 0.42
Identities = 29/157 (18%), Positives = 69/157 (43%), Gaps = 28/157 (17%)
Query: 69 DKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKE 128
++E ++R+ + + + E+ F EE +++ +++ + +E
Sbjct: 1403 EREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV-----------RRQERERKFLEE 1451
Query: 129 NKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQL-----------QQILKR 177
+ + Q+ K E++ L+E E + E+ R F+++E+QL Q++ +
Sbjct: 1452 EQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Query: 178 KNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEK 214
+ ++ FL+E + L Q + + Q E QL +
Sbjct: 1512 EPERKFLEEEQQ------LHRQQRQRKFLQEEQQLRR 1542
Score = 32.3 bits (72), Expect = 0.55
Identities = 15/63 (23%), Positives = 37/63 (58%)
Query: 119 KKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRK 178
K ++ ++ + ++Q+ + +L RE+ E E ERQ E+ +L ++E+ L++ +++
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 179 NKQ 181
+Q
Sbjct: 952 RRQ 954
Score = 31.6 bits (70), Expect = 0.93
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 4/83 (4%)
Query: 134 QKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLP 193
Q+ + + E+EE E+ +R+E E+ F+++EEQLQ +R+ Q +E +
Sbjct: 804 QQREQRFLPEEEEKEQRRR-QRREREKELQFLEEEEQLQ---RRERAQQLQEEEDGLQED 859
Query: 194 VALLLAQHKDRSTQLEMQLEKPK 216
+Q + R + QLE+ +
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEER 882
Score = 30.8 bits (68), Expect = 1.6
Identities = 19/74 (25%), Positives = 40/74 (54%), Gaps = 12/74 (16%)
Query: 119 KKKMEIYQKENKDVIQKNKLKLTREQEEL------------EEALEVERQENEQRRLFIQ 166
+++ ++Q+E + +K + L +E+E+L EE ++ + E ++ R Q
Sbjct: 232 ERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQ 291
Query: 167 KEEQLQQILKRKNK 180
+EEQ QQ L+R+ +
Sbjct: 292 EEEQQQQRLRREQQ 305
Score = 30.8 bits (68), Expect = 1.6
Identities = 37/167 (22%), Positives = 79/167 (47%), Gaps = 21/167 (12%)
Query: 53 LRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNN 112
L + R Q E ++ E ++R++ + ++E D RE L+E EE +
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD-RKFREDEQLLQEREEQQLHRQER 1641
Query: 113 VDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQK----- 167
D +++ ++ ++E + ++ ++ + RE+E+L QE E+++L Q+
Sbjct: 1642 -DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQL-------LQEGEEQQLRRQERDRKF 1693
Query: 168 EEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEK 214
E+ QQ+ +++ ++ FL E + L Q +R + E QL +
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQ-------LRRQELERKFREEEQLRQ 1733
Score = 30.4 bits (67), Expect = 2.1
Identities = 23/96 (23%), Positives = 48/96 (50%), Gaps = 8/96 (8%)
Query: 127 KENKDVIQKNKLKLTREQEELEEALEVERQEN------EQRRLFIQKEEQLQQILKRKNK 180
+ + + ++ +L+ +E+E E+ E ER+E E+RR ++++EE+ ++ + + K
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Query: 181 QAFLDELESSDLPVALLLAQHKDRSTQ--LEMQLEK 214
Q + E L L + + R Q E QL +
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Score = 30.4 bits (67), Expect = 2.1
Identities = 27/129 (20%), Positives = 64/129 (49%), Gaps = 6/129 (4%)
Query: 85 REEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQ 144
RE++ S FLEE +++ L +++ ++ ++E ++++ + RE+
Sbjct: 1504 REQELRSQEPERKFLEEEQQLHRQQRQRKFL---QEEQQLRRQERGQQRRQDRDRKFREE 1560
Query: 145 EELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFL-DELESSDLPVALLLAQHKD 203
E+L + E ++ ++R + EE Q++ +++ ++ F+ DE + L Q +D
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEE--QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 204 RSTQLEMQL 212
R + + QL
Sbjct: 1619 RKFREDEQL 1627
Score = 29.6 bits (65), Expect = 3.5
Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 15/90 (16%)
Query: 125 YQKENKDVIQKNKLKLT---REQEELEEALEVERQENEQRRL--FIQKEEQLQQILKRKN 179
+Q E K + +L REQ E + E ERQ+ EQR L +KE++ +Q +R+
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAE-ERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 180 KQAFLDELESSDLPVALLLAQHKDRSTQLE 209
+ FL+E E Q ++R+ QL+
Sbjct: 830 ELQFLEEEEQ---------LQRRERAQQLQ 850
Score = 29.3 bits (64), Expect = 4.6
Identities = 24/118 (20%), Positives = 53/118 (44%), Gaps = 1/118 (0%)
Query: 64 EDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKME 123
E+ + + + +++ + +R E E +E E D K+ E
Sbjct: 524 EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREE 583
Query: 124 IYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQ 181
+++ Q+ +L+ ++EE+E + ER+E +R +EE+ QQ+LK + ++
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR-EEPEEERRQQLLKSEEQE 640
Score = 29.3 bits (64), Expect = 4.6
Identities = 36/178 (20%), Positives = 81/178 (45%), Gaps = 16/178 (8%)
Query: 60 VQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTK 119
+Q E+ + +E E R++ + + EE+ + + +E + + +N
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 120 KKMEIYQK--ENKDV--IQKNKLKLTREQEELEEAL--------EVERQENEQRRLFIQK 167
+ ++Y K EN+ ++ ++L+ + Q++L+ L E ER+ +QR +
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 168 EEQL----QQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPV 221
EEQL Q+ KR+++++ ++ + Q DR + E QL + + +P+
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Score = 28.5 bits (62), Expect = 7.9
Identities = 40/166 (24%), Positives = 74/166 (44%), Gaps = 35/166 (21%)
Query: 47 PECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIV 106
P LRK QL ++ + + E R+K +R+E RE +E E++
Sbjct: 893 PALQEQLRKEQ---QLLQEEEEELQREEREK-----RRRQEQERQYREEEQLQQEEEQL- 943
Query: 107 FNLTNNVDLDNTKKKMEIYQKENKDVIQKNKL--------------KLTREQEEL-EEAL 151
L + +++ Y+K+ K ++ +L K RE+EEL +E
Sbjct: 944 --LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Query: 152 EVERQENEQRR-----LFIQKEEQLQ----QILKRKNKQAFLDELE 188
++ R+E E+RR +K+++LQ Q+L+ + ++ L E E
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Score = 28.5 bits (62), Expect = 7.9
Identities = 21/103 (20%), Positives = 52/103 (50%), Gaps = 3/103 (2%)
Query: 84 KREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTRE 143
+R++ RE +E EE + D ++ ++ ++E + +++ +L R+
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQER-DRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 144 QEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDE 186
+ + + E +R+ E +L ++EEQ Q+ +++ + FL+E
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREEQ--QLHRQERDRKFLEE 1648
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 39.7 bits (91), Expect = 0.003
Identities = 30/159 (18%), Positives = 77/159 (48%), Gaps = 10/159 (6%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKEN 129
+E E+ + + + KR+E + F +V+E+ + ++++ ++E + +
Sbjct: 2185 EEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLS 2244
Query: 130 KDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELE- 188
+ ++ + + RE+EE+ E E ++E E ++KEE+ ++ K++ K+ + E E
Sbjct: 2245 SEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304
Query: 189 ---------SSDLPVALLLAQHKDRSTQLEMQLEKPKPV 218
S + +L + ++ S LE ++++ K +
Sbjct: 2305 VFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEI 2343
Score = 36.6 bits (83), Expect = 0.029
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 44/166 (26%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKEN 129
K ++ +K +K+ KRE ++ +EE+ TK KM +YQK+N
Sbjct: 1801 KREQLIEKKMKLAQKRER----------WINSMEEL------------TKNKMILYQKKN 1838
Query: 130 ----KDVIQKNKLKLTREQEEL-----------EEALEVERQENEQRRLFIQKEEQLQQ- 173
K + + K KL + +E L ++ ++V+ + ++ Q EE+L Q
Sbjct: 1839 LAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE 1898
Query: 174 ---ILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPK 216
++K+K K L E E + V LA+ +++ Q +M+L K
Sbjct: 1899 KETVIKKKEK---LAETEKKLVQVEDSLAKKQEKLAQEKMKLALEK 1941
Score = 34.3 bits (77), Expect = 0.14
Identities = 36/145 (24%), Positives = 69/145 (47%), Gaps = 35/145 (24%)
Query: 77 KVLKIYNKREEDFPSLREYNDFLE-----EVEEIVFNLTNNVDLDNTKKKMEIYQKENKD 131
+V I ++ E+ P + D+ E E+EE+ +++ + + K+ E+ Q+E K
Sbjct: 1688 EVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDME-----ELSWKEEELNQEEGKL 1742
Query: 132 VIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSD 191
V +K KL E EEAL +R++ + + +EE+L +++ K K
Sbjct: 1743 VEEKKKLA------EEEEALAWQREKLSEEETKLAQEEEL--LIQEKEK----------- 1783
Query: 192 LPVALLLAQHKDRSTQLEMQLEKPK 216
LAQHK++ + E +L + +
Sbjct: 1784 ------LAQHKEKMPEEEERLGRKR 1802
Score = 33.5 bits (75), Expect = 0.25
Identities = 48/215 (22%), Positives = 92/215 (42%), Gaps = 37/215 (17%)
Query: 69 DKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKE 128
++E E ++ ++ + EE +E+ EE + ++K E+++++
Sbjct: 2250 EREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK 2309
Query: 129 NKDVIQKNKLKLTREQEE-----LEEALEVERQ---------ENEQRRLFIQKEEQLQQI 174
+ + ++ L+ E+EE LEE ++ E++ EQRR ++ E++ I
Sbjct: 2310 EEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSI 2369
Query: 175 LK----RKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMG 230
L+ K + L L+S P+ L+ ST LEM+ + P PV S K
Sbjct: 2370 LRGVPHGKGRAIRLGVLKS---PLKKLM------STALEMKEKTPVPVPEKQISWEDKKA 2420
Query: 231 QHIS-----LAPIHKLEEALYEYQPLQIETYGPHV 260
+ L + K E + +Y+P+ PHV
Sbjct: 2421 TVVEIPRKFLGTMDKEREVMGKYEPIP-----PHV 2450
Score = 31.2 bits (69), Expect = 1.2
Identities = 21/110 (19%), Positives = 54/110 (49%), Gaps = 9/110 (8%)
Query: 84 KREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTRE 143
K+ D L E L++ ++++F NV + EI +KE K QK+ + +
Sbjct: 1352 KKARDMLGLEETQVILKKGKKVIFLEPGNVTMGK-----EISKKEEKKTFQKSPKQGRKA 1406
Query: 144 QEELEEALEVERQENEQRRLFIQKEEQL----QQILKRKNKQAFLDELES 189
++ + +++R+ ++ R ++ E++ ++++K++ K ++ S
Sbjct: 1407 VQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPS 1456
Score = 28.9 bits (63), Expect = 6.0
Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 18/142 (12%)
Query: 73 EIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNV--DLDNTKKKMEIYQKENK 130
E K++L+ K + L + L+E +++ + V ++ ++K K + Y+ E +
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543
Query: 131 DVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESS 190
+T E+E E E E+Q E++R IQ+E + +I +++ + E
Sbjct: 1544 ---------VTLEEEVSREGEEKEQQVTEEQR-HIQEEHKWARIHRKRAR------AEKK 1587
Query: 191 DLPVALLLAQHKDRSTQLEMQL 212
LAQ +++ Q E QL
Sbjct: 1588 RAQEERKLAQEEEKLAQEERQL 1609
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 39.3 bits (90), Expect = 0.004
Identities = 30/82 (36%), Positives = 52/82 (63%), Gaps = 6/82 (7%)
Query: 139 KLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLL 198
+L ++++ELE E+ERQ+ EQR+L ++ +E+LQQ+ ++ +Q +LE + V L L
Sbjct: 334 ELEQQRQELERQQELERQQ-EQRQLQLKLQEELQQLEQQLEQQQ--QQLEQQE--VQLEL 388
Query: 199 AQHKDRSTQLEMQLEKPKPVKP 220
+ + Q E+QLE PV+P
Sbjct: 389 TPVELGAQQQEVQLEL-TPVQP 409
Score = 36.2 bits (82), Expect = 0.038
Identities = 29/105 (27%), Positives = 56/105 (53%), Gaps = 19/105 (18%)
Query: 126 QKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQ-----ILKRKNK 180
Q++ + +Q+ +L L ++QE+L++ +++QE Q++ F Q++EQLQQ +L+++ +
Sbjct: 191 QEQLQQQVQEQQL-LQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQ 249
Query: 181 -------------QAFLDELESSDLPVALLLAQHKDRSTQLEMQL 212
Q L E + + L LLL Q + Q + QL
Sbjct: 250 LQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQL 294
Score = 35.0 bits (79), Expect = 0.084
Identities = 36/168 (21%), Positives = 83/168 (49%), Gaps = 12/168 (7%)
Query: 109 LTNNVDLDNTKKKMEIYQKENKDVIQKNKLKL----TREQEELEEALEVERQENEQRRLF 164
L + L + +++++ Q + + +Q+ + +L +EQ+ L++ ++++Q EQ+ L
Sbjct: 146 LKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQ 205
Query: 165 IQKEE-QLQQILKRK---NKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKP 220
Q+E+ Q QQ+L+++ +Q F + E LLL Q + + Q +Q ++ + +
Sbjct: 206 QQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQ 265
Query: 221 VTFSTGIKMGQHISLAPIHKL----EEALYEYQPLQIETYGPHVPELE 264
+ ++ Q + L +L ++ L + Q Q++ P LE
Sbjct: 266 LLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLE 313
Score = 33.5 bits (75), Expect = 0.25
Identities = 20/78 (25%), Positives = 45/78 (57%), Gaps = 1/78 (1%)
Query: 90 PSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKN-KLKLTREQEELE 148
P L + E+E + +L + +L+ ++++E Q+ + Q+ +LKL E ++LE
Sbjct: 310 PPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLE 369
Query: 149 EALEVERQENEQRRLFIQ 166
+ LE ++Q+ EQ+ + ++
Sbjct: 370 QQLEQQQQQLEQQEVQLE 387
Score = 30.4 bits (67), Expect = 2.1
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 14/114 (12%)
Query: 100 EEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENE 159
EE EE+ L VDL + ++ +++ +++ ++ +L+ +EQ +L+ L+ E Q+ E
Sbjct: 315 EEEEEVELELMP-VDLGSEQE----LEQQRQELERQQELERQQEQRQLQLKLQEELQQLE 369
Query: 160 QRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLE 213
Q Q E+Q QQ+ +Q EL +L Q + Q E+QLE
Sbjct: 370 Q-----QLEQQQQQL----EQQEVQLELTPVELGAQQQEVQLELTPVQPELQLE 414
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/176 (18%), Positives = 80/176 (45%), Gaps = 15/176 (8%)
Query: 53 LRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKRE---EDFPSLREYNDFLEEVEEIVFNL 109
+RK +V E+ D+E +IR++ K++ + E E +RE + + E EE++
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQ 549
Query: 110 TNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALE------------VERQE 157
+ K + + + ++ I++ + K+ ++E++ E E E +
Sbjct: 550 EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 609
Query: 158 NEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLE 213
++ +++ Q+E+ +Q K + ++ + E + L Q +++ + + LE
Sbjct: 610 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 34.3 bits (77), Expect = 0.14
Identities = 31/171 (18%), Positives = 86/171 (50%), Gaps = 9/171 (5%)
Query: 58 FRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDN 117
+R + ++ +K ++++K+ + +++ E +++E LE + ++ + D+
Sbjct: 210 YRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH 269
Query: 118 TKKKMEIYQKENKDVIQKNKL--KLTREQEEL-----EEALEVERQENEQRRLFIQKEEQ 170
K+++ + + +++N+L +L ++QEE E+ E E + EQ ++EE+
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK 329
Query: 171 L-QQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQL-EMQLEKPKPVK 219
+ +Q K + ++ + E E ++ + +++ +L EM EK + ++
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIR 380
Score = 29.3 bits (64), Expect = 4.6
Identities = 27/133 (20%), Positives = 67/133 (50%), Gaps = 7/133 (5%)
Query: 61 QLFEDPTVDKEVEIRKKVLKI--YNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNT 118
++ E + ++ E R++ KI KR+E + + + E EE + +
Sbjct: 385 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK--MWRQ 442
Query: 119 KKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQE---NEQRRLFIQKEEQLQQIL 175
++K+ +K ++ ++ + ++ R++E++ E E+ RQ+ +EQ ++ Q+E+ +Q
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEE 502
Query: 176 KRKNKQAFLDELE 188
K +++ + E E
Sbjct: 503 KMHDQEEKIREQE 515
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 39.3 bits (90), Expect = 0.004
Identities = 40/171 (23%), Positives = 83/171 (48%), Gaps = 20/171 (11%)
Query: 53 LRKSNFRVQLFED--PTVDK-----EVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEI 105
L K N V + +D P ++K E+ I + KI + +EY+ ++ EE+
Sbjct: 850 LDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEEL 909
Query: 106 VFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFI 165
+ L KKK Q+E + +++ + ++ +E++ EE + R+E E+RR+ +
Sbjct: 910 LSALQ--------KKKQ---QEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKL 958
Query: 166 QKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPK 216
+ E + +Q + + K+ D+ + V LA+ K+ +Q + LE+ +
Sbjct: 959 EMEAKRKQEEEERKKRE--DDEKRIQAEVEAQLARQKEEESQQQAVLEQER 1007
Score = 28.5 bits (62), Expect = 7.9
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 4/112 (3%)
Query: 70 KEVEIRKKVLKIYNKREEDFPSLREYNDFLEEV----EEIVFNLTNNVDLDNTKKKMEIY 125
K E L+ ++EE+ LR + +E+ EE + K +ME
Sbjct: 904 KSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAK 963
Query: 126 QKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKR 177
+K+ ++ +K + R Q E+E L +++E Q++ +++E + +++ R
Sbjct: 964 RKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALR 1015
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 39.3 bits (90), Expect = 0.004
Identities = 34/125 (27%), Positives = 63/125 (50%), Gaps = 8/125 (6%)
Query: 69 DKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKE 128
+K E + + LK N++E ++ ++ + E+ NLT V+ N KK+ QKE
Sbjct: 517 EKWKEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTA-VEKWNEKKEAFFKQKE 575
Query: 129 NKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELE 188
+ + +K K +L R +++ ++ + NE + KE+Q + K+K + +F LE
Sbjct: 576 KEKINEKRKEELKRAEKKDKDKQAI----NEYEKWLENKEKQERIERKQKKRHSF---LE 628
Query: 189 SSDLP 193
S LP
Sbjct: 629 SEALP 633
Score = 30.8 bits (68), Expect = 1.6
Identities = 46/192 (23%), Positives = 72/192 (37%), Gaps = 33/192 (17%)
Query: 52 PLRKSNFRVQLFEDPTVDKEV---------EIRKKVLKIYN------KREEDFPSLREYN 96
P R N R ++++ K V I + L+I N KREE S +
Sbjct: 418 PDRADNIRAAVYQEWLEKKNVYLHEMHRIKRIESENLRIQNEQKKAAKREEALASFEAWK 477
Query: 97 DFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQ 156
++E E ++ N KK E + +Q + ++ E L+E R+
Sbjct: 478 A-MKEKEAKKIAAKKRLEEKNKKKTEEENAARKGEALQAFEKWKEKKMEYLKEK---NRK 533
Query: 157 ENEQRRLFIQKEEQLQQILKRKN----------KQAFLDELESSDL----PVALLLAQHK 202
E E R QKEE+ K+ N K+AF + E + L A+ K
Sbjct: 534 EREYERAKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRAEKK 593
Query: 203 DRSTQLEMQLEK 214
D+ Q + EK
Sbjct: 594 DKDKQAINEYEK 605
Score = 30.0 bits (66), Expect = 2.7
Identities = 29/118 (24%), Positives = 56/118 (47%), Gaps = 16/118 (13%)
Query: 53 LRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNN 112
L++ N + + +E KE E + K++++ ++ ++N E +E F
Sbjct: 527 LKEKNRKEREYERAKKQKEEET------VAEKKKDNLTAVEKWN----EKKEAFFKQKEK 576
Query: 113 VDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQ--RRLFIQKE 168
+ N K+K E+ + E KD K+K + ++ LE + ER E +Q R F++ E
Sbjct: 577 EKI-NEKRKEELKRAEKKD---KDKQAINEYEKWLENKEKQERIERKQKKRHSFLESE 630
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 38.9 bits (89), Expect = 0.006
Identities = 41/171 (23%), Positives = 81/171 (47%), Gaps = 18/171 (10%)
Query: 54 RKSNFRVQLFEDPTVDKEVEIRKKVL---KIYNKREEDFPSLREYNDFLEEVE-EIVFNL 109
+K QL + ++KE ++++ V ++ K EE + E + ++ +E E L
Sbjct: 147 KKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLL 206
Query: 110 TNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTRE----QEELEEALEVERQENEQRRLFI 165
+ L+N ++ Q ++ K+ L RE QE++ V +++ R I
Sbjct: 207 ERKLSLEN-----KLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVI 261
Query: 166 QKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPK 216
Q+ E L+ LK ++K+ +E+ V +L AQ+K+ TQ+ + E P+
Sbjct: 262 QEMEGLKNNLKEQDKR-----IENLREKVNILEAQNKELKTQVALSSETPR 307
Score = 31.2 bits (69), Expect = 1.2
Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 17/95 (17%)
Query: 119 KKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQIL-KR 177
++ E YQ ++++V +K QE+ ++ L+V + E EQ+ Q E L Q+ K
Sbjct: 132 QRLFENYQTQSEEVRKK--------QEDSKQLLQVNKLEKEQK--LKQHVENLNQVAEKL 181
Query: 178 KNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQL 212
+ K + + ELE+ L+ K++ T LE +L
Sbjct: 182 EEKHSQITELEN------LVQRMEKEKRTLLERKL 210
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 38.9 bits (89), Expect = 0.006
Identities = 41/171 (23%), Positives = 81/171 (47%), Gaps = 18/171 (10%)
Query: 54 RKSNFRVQLFEDPTVDKEVEIRKKVL---KIYNKREEDFPSLREYNDFLEEVE-EIVFNL 109
+K QL + ++KE ++++ V ++ K EE + E + ++ +E E L
Sbjct: 147 KKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLL 206
Query: 110 TNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTRE----QEELEEALEVERQENEQRRLFI 165
+ L+N ++ Q ++ K+ L RE QE++ V +++ R I
Sbjct: 207 ERKLSLEN-----KLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVI 261
Query: 166 QKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPK 216
Q+ E L+ LK ++K+ +E+ V +L AQ+K+ TQ+ + E P+
Sbjct: 262 QEMEGLKNNLKEQDKR-----IENLREKVNILEAQNKELKTQVALSSETPR 307
Score = 31.2 bits (69), Expect = 1.2
Identities = 27/95 (28%), Positives = 49/95 (51%), Gaps = 17/95 (17%)
Query: 119 KKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQIL-KR 177
++ E YQ ++++V +K QE+ ++ L+V + E EQ+ Q E L Q+ K
Sbjct: 132 QRLFENYQTQSEEVRKK--------QEDSKQLLQVNKLEKEQK--LKQHVENLNQVAEKL 181
Query: 178 KNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQL 212
+ K + + ELE+ L+ K++ T LE +L
Sbjct: 182 EEKHSQITELEN------LVQRMEKEKRTLLERKL 210
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/141 (25%), Positives = 72/141 (51%), Gaps = 8/141 (5%)
Query: 79 LKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNV-DLDNTKKKMEIYQKENKDVIQKNK 137
L+ K+ + + + D ++ +E++ T + L++TK+ Q E D +++N
Sbjct: 1026 LEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNE-LDTLKENN 1084
Query: 138 LKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALL 197
LK E + +E L VE Q+ E+ F ++ E L+Q +K++Q L L+ ++ +A
Sbjct: 1085 LKNVEELNKSKELLTVENQKMEE---FRKEIETLKQAAAQKSQQ--LSALQEENVKLAEE 1139
Query: 198 LAQHKDRSTQLEMQLEKPKPV 218
L + +D T +LE+ + V
Sbjct: 1140 LGRSRDEVTS-HQKLEEERSV 1159
Score = 29.3 bits (64), Expect = 4.6
Identities = 39/179 (21%), Positives = 77/179 (43%), Gaps = 33/179 (18%)
Query: 68 VDKEVEIRKKVLKIYNKRE-------EDFPSLREYNDFLEEVEE----IVFNLTNNVDLD 116
VD + + +++ + K E + SL+E+ EE + ++ T + +
Sbjct: 496 VDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKE 555
Query: 117 NT--KKKMEIYQKENKDVIQ--KNKLK--LTREQEELEEALEVE---------------R 155
N K K+E KEN DVI K+KL+ + Q+ +EE L+V +
Sbjct: 556 NESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEE-LKVSFSKGLGTETAEFAELK 614
Query: 156 QENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEK 214
+ E+ RL Q E + Q + + A E+E+ + ++ + ++ + +L+K
Sbjct: 615 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDK 673
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 38.9 bits (89), Expect = 0.006
Identities = 36/141 (25%), Positives = 72/141 (51%), Gaps = 8/141 (5%)
Query: 79 LKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNV-DLDNTKKKMEIYQKENKDVIQKNK 137
L+ K+ + + + D ++ +E++ T + L++TK+ Q E D +++N
Sbjct: 1061 LEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNE-LDTLKENN 1119
Query: 138 LKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALL 197
LK E + +E L VE Q+ E+ F ++ E L+Q +K++Q L L+ ++ +A
Sbjct: 1120 LKNVEELNKSKELLTVENQKMEE---FRKEIETLKQAAAQKSQQ--LSALQEENVKLAEE 1174
Query: 198 LAQHKDRSTQLEMQLEKPKPV 218
L + +D T +LE+ + V
Sbjct: 1175 LGRSRDEVTS-HQKLEEERSV 1194
Score = 29.3 bits (64), Expect = 4.6
Identities = 39/179 (21%), Positives = 77/179 (43%), Gaps = 33/179 (18%)
Query: 68 VDKEVEIRKKVLKIYNKRE-------EDFPSLREYNDFLEEVEE----IVFNLTNNVDLD 116
VD + + +++ + K E + SL+E+ EE + ++ T + +
Sbjct: 531 VDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKE 590
Query: 117 NT--KKKMEIYQKENKDVIQ--KNKLK--LTREQEELEEALEVE---------------R 155
N K K+E KEN DVI K+KL+ + Q+ +EE L+V +
Sbjct: 591 NESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEE-LKVSFSKGLGTETAEFAELK 649
Query: 156 QENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEK 214
+ E+ RL Q E + Q + + A E+E+ + ++ + ++ + +L+K
Sbjct: 650 TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDK 708
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 38.5 bits (88), Expect = 0.008
Identities = 45/193 (23%), Positives = 83/193 (43%), Gaps = 39/193 (20%)
Query: 59 RVQLFEDPTVDKEVEIRKKVLKIYNKREE-----DFPSLREYNDFLEE--VEEIVFNLTN 111
+V+ ++ +K E KK+ ++ N++E D + ++ L +EE F LT
Sbjct: 859 QVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQ 918
Query: 112 N------------VDLDNT-----------KKKMEIYQKENKDVIQKNK-----LKLTRE 143
D D+T K +EI ++EN+++ +K K KL +E
Sbjct: 919 ESKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKE 978
Query: 144 QEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKD 203
+E E+ N +R L Q +L +I+ RK+ + + + D L + ++
Sbjct: 979 EEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQD----LRKKEKEN 1034
Query: 204 RSTQLEMQLEKPK 216
R QLE+ E+ K
Sbjct: 1035 RKLQLELNQEREK 1047
Score = 30.0 bits (66), Expect = 2.7
Identities = 26/111 (23%), Positives = 55/111 (49%), Gaps = 11/111 (9%)
Query: 74 IRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVI 133
++++V + + E+ +E D L E+ NN+++D K + Q+ ++V
Sbjct: 634 LQEEVKHLKHNLEKVEGERKEAQDMLNHSEKE----KNNLEIDLNYKLKSLQQRLEQEVN 689
Query: 134 QKN--KLKLTREQEELEEA-----LEVERQENEQRRLFIQKEEQLQQILKR 177
+ K +LT + + +EEA E+E++ E+R + E ++ QI K+
Sbjct: 690 EHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ 740
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,295,118
Number of Sequences: 37866
Number of extensions: 603972
Number of successful extensions: 6627
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 680
Number of HSP's that attempted gapping in prelim test: 4067
Number of HSP's gapped (non-prelim): 2376
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.