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Search of human proteins with 13027636
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
(382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens] 757 0.0
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens] 382 e-106
gi|134244587 endothelial differentiation, sphingolipid G-protein... 331 8e-91
gi|13540517 endothelial differentiation, sphingolipid G-protein-... 322 5e-88
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 244 9e-65
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens] 241 1e-63
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens] 241 1e-63
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens] 209 3e-54
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens] 206 4e-53
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens] 130 2e-30
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens] 130 2e-30
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens] 130 2e-30
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens] 130 2e-30
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens] 130 2e-30
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens] 130 2e-30
gi|4885325 G protein-coupled receptor 3 [Homo sapiens] 126 3e-29
gi|4885295 G protein-coupled receptor 12 [Homo sapiens] 124 1e-28
gi|119508433 melanocortin 4 receptor [Homo sapiens] 121 1e-27
gi|5174535 melanocortin 5 receptor [Homo sapiens] 117 1e-26
gi|4885341 G protein-coupled receptor 6 [Homo sapiens] 114 1e-25
gi|170671732 melanocortin 3 receptor [Homo sapiens] 111 9e-25
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 109 4e-24
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 108 1e-23
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 108 1e-23
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 108 1e-23
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 108 1e-23
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 108 1e-23
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 105 7e-23
gi|5921992 adenosine A2a receptor [Homo sapiens] 105 9e-23
gi|4505127 melanocortin 2 receptor [Homo sapiens] 104 2e-22
>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
Length = 382
Score = 757 bits (1955), Expect = 0.0
Identities = 382/382 (100%), Positives = 382/382 (100%)
Query: 1 MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII 60
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
Sbjct: 1 MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII 60
Query: 61 LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR 120
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
Sbjct: 61 LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR 120
Query: 121 EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM 180
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
Sbjct: 121 EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM 180
Query: 181 GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN 240
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
Sbjct: 181 GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN 240
Query: 241 ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA 300
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
Sbjct: 241 ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA 300
Query: 301 VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH 360
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
Sbjct: 301 VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH 360
Query: 361 PQKDEGDNPETIMSSGNVNSSS 382
PQKDEGDNPETIMSSGNVNSSS
Sbjct: 361 PQKDEGDNPETIMSSGNVNSSS 382
>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
Length = 378
Score = 382 bits (981), Expect = e-106
Identities = 197/353 (55%), Positives = 254/353 (71%), Gaps = 16/353 (4%)
Query: 28 HYNYTGKL--NISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIG 85
HY Y GKL + E S LT+V+F++IC FI+LEN+ VL+ IWK KFH MY+FIG
Sbjct: 21 HYQYVGKLAGRLKEASEGST-LTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIG 79
Query: 86 NLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYIT 145
NLAL DLLAG+AY N+L+SG T+ L+P WFLREGSMFVAL AS SLLAIAIER++T
Sbjct: 80 NLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLT 139
Query: 146 MLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILF 205
M+KM+ ++ + R+FLLI CW+I+ LG LPI+GWNC+ L CST+LPLY K YI F
Sbjct: 140 MIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAF 199
Query: 206 CTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVF 265
C ++FT +L++IVILY RIY LV++ SR++ N SE+S+ALL+TV+IV+SVF
Sbjct: 200 CISIFTAILVTIVILYARIYFLVKSSSRKVANHNN-------SERSMALLRTVVIVVSVF 252
Query: 266 IACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRI 325
IACW+PLFIL L+DV C+V+ C ILF+A++F+VLAVLNS NP+IYTL +KEMRRAF R+
Sbjct: 253 IACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRL 312
Query: 326 MSCCKCPSGDSAGKFKRPIIAGMEFSRSK---SDNSSHPQKDEGDNPETIMSS 375
+ C C G PI ++ SRSK S+NSSH K + D P T SS
Sbjct: 313 V--CNC-LVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSS 362
>gi|134244587 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 5 [Homo sapiens]
Length = 353
Score = 331 bits (848), Expect = 8e-91
Identities = 161/315 (51%), Positives = 220/315 (69%), Gaps = 12/315 (3%)
Query: 14 SSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKT 73
S S+Y+N + + HYNYT K + + S ++ S +++CC I++EN+ VL+ + +
Sbjct: 3 SLYSEYLNPNKVQEHYNYT-KETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARN 61
Query: 74 KKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVF 133
KFH MY F+GNLA SDLLAGVA+ AN LLSG+ T +LTP QWF REGS F+ LSASVF
Sbjct: 62 SKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVF 121
Query: 134 SLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCST 193
SLLAIAIER++ + K+KL+ + R+ LLI A W+ISL+LGGLPI+GWNC+ L +CST
Sbjct: 122 SLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACST 181
Query: 194 VLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLA 253
VLPLY KHY+L T+F+++LL+IV LY RIY +VR+ S A ++ ++LA
Sbjct: 182 VLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRS-----------SHADMAAPQTLA 230
Query: 254 LLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTL 313
LLKTV IVL VFI CW P F +LLLD C V +C IL++A YF ++ LNS NP+IYT
Sbjct: 231 LLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTW 290
Query: 314 TNKEMRRAFIRIMSC 328
++++RR +R + C
Sbjct: 291 RSRDLRREVLRPLQC 305
>gi|13540517 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 8 [Homo sapiens]
Length = 398
Score = 322 bits (824), Expect = 5e-88
Identities = 176/372 (47%), Positives = 242/372 (65%), Gaps = 19/372 (5%)
Query: 23 DIIVRHYNYTGKLNISADKENS-IKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMY 81
++IV HYNYTGKL + + + ++ +VV + +C FI+LEN+ VLL + + +FH PM+
Sbjct: 13 EVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHPRFHAPMF 72
Query: 82 YFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIE 141
+G+L LSDLLAG AY AN+LLSG T KL+PA WF REG +FVAL+ASV SLLAIA+E
Sbjct: 73 LLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLAIALE 132
Query: 142 RYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKH 201
R +TM + S+ R + +A W +SL+LG LP +GWNC+ L +CSTVLPLY K
Sbjct: 133 RSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKA 192
Query: 202 YILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRK----NISKASRSSEKSLALLKT 257
Y+LFC F +L +I LY RIY VR +RRL R S +R +SLALL+T
Sbjct: 193 YVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLALLRT 252
Query: 258 VIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKE 317
+ +VL F+ACW PLF+LLLLDV C +TC +L +A+ FL LA+ NS NPIIYTLTN++
Sbjct: 253 LSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTLTNRD 312
Query: 318 MRRAFIRIM-----SCCKCPSG--------DSAGKFKRPIIAGMEFSRSKSDNSSHPQKD 364
+R A +R++ SC + PSG +++G +R + G++ S S S+ SS PQ+D
Sbjct: 313 LRHALLRLVCCGRHSCGRDPSGSQQSASAAEASGGLRRCLPPGLDGSFSGSERSS-PQRD 371
Query: 365 EGDNPETIMSSG 376
D + S G
Sbjct: 372 GLDTSGSTGSPG 383
>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
Length = 384
Score = 244 bits (623), Expect = 9e-65
Identities = 133/334 (39%), Positives = 199/334 (59%), Gaps = 11/334 (3%)
Query: 1 MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKL-NISADKENSIKLTSVVFILICCFI 59
M T P+ ++ + +IV HYN++G+L ++ + + + C +
Sbjct: 1 MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV 60
Query: 60 ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL 119
+LEN+ VL I + R +YY + N+ LSDLL G AY AN+LLSGA T++L PAQWFL
Sbjct: 61 VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL 120
Query: 120 REGSMFVALSASVFSLLAIAIERYITMLKMKLHNG-SNNFRLFLLISACWVISLILGGLP 178
REG +F AL+AS FSLL A ER+ TM++ +G + R++ I CW+++ +LG LP
Sbjct: 121 REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP 180
Query: 179 IMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFR 238
++GWNC+ A CS++LPLY K YILFC +F +L +I+ LY I+ LV+ ++
Sbjct: 181 LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQK---- 236
Query: 239 KNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV-GCKVKTCDILFRAEYFL 297
+ + K+ LLKTV+++L F+ CW PLF LLL DV G + + L ++ L
Sbjct: 237 ---APRPAARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWIL 293
Query: 298 VLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKC 331
LAVLNS NPIIY+ ++E+ RA + + CC C
Sbjct: 294 ALAVLNSAVNPIIYSFRSREVCRAVLSFL-CCGC 326
>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 241 bits (614), Expect = 1e-63
Identities = 132/357 (36%), Positives = 215/357 (60%), Gaps = 18/357 (5%)
Query: 4 TSVPLVKAHRSSVSD----YVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFI 59
TS+P++ + + + + N + I YN +GK +++ + KL + I +C FI
Sbjct: 6 TSIPVISQPQFTAMNEPQCFYN-ESIAFFYNRSGK-HLATEWNTVSKLVMGLGITVCIFI 63
Query: 60 ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL 119
+L N+ V++ I+ ++FH P+YY + NLA +D AG+AY + +G T +LT + W L
Sbjct: 64 MLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLL 123
Query: 120 REGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPI 179
R+G + +L+ASV +LLAIAIER+IT+ +M+LH +N R+ ++I W +++++G +P
Sbjct: 124 RQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPS 183
Query: 180 MGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRK 239
+GWNCI + +CS + PLY Y++F + + +V+LY I+ VR R+ R++ +
Sbjct: 184 VGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS--R 241
Query: 240 NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVL 299
+ S R+ + ++LLKTV+IVL FI CW P +LLLLDV C CD+L ++FL+L
Sbjct: 242 HSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCC--PQCDVLAYEKFFLLL 299
Query: 300 AVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKC--PSGD------SAGKFKRPIIAGM 348
A NS NPIIY+ +KEM F +I+ C + P+G SA I+AG+
Sbjct: 300 AEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGV 356
>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 241 bits (614), Expect = 1e-63
Identities = 132/357 (36%), Positives = 215/357 (60%), Gaps = 18/357 (5%)
Query: 4 TSVPLVKAHRSSVSD----YVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFI 59
TS+P++ + + + + N + I YN +GK +++ + KL + I +C FI
Sbjct: 6 TSIPVISQPQFTAMNEPQCFYN-ESIAFFYNRSGK-HLATEWNTVSKLVMGLGITVCIFI 63
Query: 60 ILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFL 119
+L N+ V++ I+ ++FH P+YY + NLA +D AG+AY + +G T +LT + W L
Sbjct: 64 MLANLLVMVAIYVNRRFHFPIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLL 123
Query: 120 REGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPI 179
R+G + +L+ASV +LLAIAIER+IT+ +M+LH +N R+ ++I W +++++G +P
Sbjct: 124 RQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPS 183
Query: 180 MGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRK 239
+GWNCI + +CS + PLY Y++F + + +V+LY I+ VR R+ R++ +
Sbjct: 184 VGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMS--R 241
Query: 240 NISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVL 299
+ S R+ + ++LLKTV+IVL FI CW P +LLLLDV C CD+L ++FL+L
Sbjct: 242 HSSGPRRNRDTMMSLLKTVVIVLGAFIICWTPGLVLLLLDVCC--PQCDVLAYEKFFLLL 299
Query: 300 AVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKC--PSGD------SAGKFKRPIIAGM 348
A NS NPIIY+ +KEM F +I+ C + P+G SA I+AG+
Sbjct: 300 AEFNSAMNPIIYSYRDKEMSATFRQILCCQRSENPTGPTEGSDRSASSLNHTILAGV 356
>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
Length = 351
Score = 209 bits (533), Expect = 3e-54
Identities = 115/304 (37%), Positives = 186/304 (61%), Gaps = 7/304 (2%)
Query: 29 YNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLA 88
YN +GK +S+ + + + + ++L N+ V+ I ++FH+P+YY +GNLA
Sbjct: 17 YNNSGK-ELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLA 75
Query: 89 LSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLK 148
+DL AGVAY + +G T +L+ WFLR+G + +L+ASV +LLAIA+ER+ +++
Sbjct: 76 AADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMA 135
Query: 149 MKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTT 208
++LH+ R+ +LI WV +L LG LP W+C+ AL CS + PL + Y+
Sbjct: 136 VQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWAL 195
Query: 209 VFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIAC 268
L+ L +V +Y RI+ VR R +R+ +++S R E +L+L+KTV+I+L F+ C
Sbjct: 196 SSLLVFLLMVAVYTRIFFYVRRRVQRMA--EHVSCHPRYRETTLSLVKTVVIILGAFVVC 253
Query: 269 WAPLFILLLLD-VGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMS 327
W P ++LLLD +GC ++C++L +YFL+LA NS N +Y+ + EMRR F R++
Sbjct: 254 WTPGQVVLLLDGLGC--ESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLL- 310
Query: 328 CCKC 331
CC C
Sbjct: 311 CCAC 314
>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
Length = 353
Score = 206 bits (523), Expect = 4e-53
Identities = 103/293 (35%), Positives = 176/293 (60%), Gaps = 5/293 (1%)
Query: 38 SADKENSIKLTSVVFI--LICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAG 95
+ D KL V+ + C FI N V+ + K +KFH P YY + NLA +D AG
Sbjct: 21 TVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAG 80
Query: 96 VAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGS 155
+AY + +G + LT +WFLR+G + +L+AS+ +LL IA+ER++++++M++H+
Sbjct: 81 IAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL 140
Query: 156 NNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLL 215
R+ LLI W I++ +G +P +GWNC+ +S+CS++ P+Y + Y++F T + L
Sbjct: 141 TKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFL 200
Query: 216 SIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFIL 275
+V++Y RIY V+ ++ L+ + S + R + + L+KTV+ VL F+ CW P ++
Sbjct: 201 IMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRT--PMKLMKTVMTVLGAFVVCWTPGLVV 258
Query: 276 LLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSC 328
LLLD G + C + +FL+LA+LNS NPIIY+ +++M +++ C
Sbjct: 259 LLLD-GLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICC 310
>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 130 bits (327), Expect = 2e-30
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 49 SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107
+V+ + + F +LEN+ VL I ++ RP Y+FIG+LA++DLL V + + +
Sbjct: 120 AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 179
Query: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167
K + + + G + + +ASV SL AI+RYI++ + + R +++ C
Sbjct: 180 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 238
Query: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225
W I++++ LP++GWNC S CS + P + Y++F V ++LLL IV Y I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271
+ + R+ R K+I + K + L KT++++L V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
L +++ DV K+ K +F + +L +LNS NPIIY L +K++R AF + C+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 416
>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 130 bits (327), Expect = 2e-30
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 49 SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107
+V+ + + F +LEN+ VL I ++ RP Y+FIG+LA++DLL V + + +
Sbjct: 120 AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 179
Query: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167
K + + + G + + +ASV SL AI+RYI++ + + R +++ C
Sbjct: 180 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 238
Query: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225
W I++++ LP++GWNC S CS + P + Y++F V ++LLL IV Y I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271
+ + R+ R K+I + K + L KT++++L V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
L +++ DV K+ K +F + +L +LNS NPIIY L +K++R AF + C+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 416
>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 130 bits (327), Expect = 2e-30
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 49 SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107
+V+ + + F +LEN+ VL I ++ RP Y+FIG+LA++DLL V + + +
Sbjct: 120 AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 179
Query: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167
K + + + G + + +ASV SL AI+RYI++ + + R +++ C
Sbjct: 180 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 238
Query: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225
W I++++ LP++GWNC S CS + P + Y++F V ++LLL IV Y I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271
+ + R+ R K+I + K + L KT++++L V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
L +++ DV K+ K +F + +L +LNS NPIIY L +K++R AF + C+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 416
>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 130 bits (327), Expect = 2e-30
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 49 SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107
+V+ + + F +LEN+ VL I ++ RP Y+FIG+LA++DLL V + + +
Sbjct: 120 AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 179
Query: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167
K + + + G + + +ASV SL AI+RYI++ + + R +++ C
Sbjct: 180 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 238
Query: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225
W I++++ LP++GWNC S CS + P + Y++F V ++LLL IV Y I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271
+ + R+ R K+I + K + L KT++++L V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
L +++ DV K+ K +F + +L +LNS NPIIY L +K++R AF + C+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 416
>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 130 bits (327), Expect = 2e-30
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 49 SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107
+V+ + + F +LEN+ VL I ++ RP Y+FIG+LA++DLL V + + +
Sbjct: 120 AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 179
Query: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167
K + + + G + + +ASV SL AI+RYI++ + + R +++ C
Sbjct: 180 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 238
Query: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225
W I++++ LP++GWNC S CS + P + Y++F V ++LLL IV Y I
Sbjct: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
Query: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271
+ + R+ R K+I + K + L KT++++L V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
L +++ DV K+ K +F + +L +LNS NPIIY L +K++R AF + C+
Sbjct: 359 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 416
>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
Length = 439
Score = 130 bits (327), Expect = 2e-30
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 49 SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107
+V+ + + F +LEN+ VL I ++ RP Y+FIG+LA++DLL V + + +
Sbjct: 87 AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 146
Query: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167
K + + + G + + +ASV SL AI+RYI++ + + R +++ C
Sbjct: 147 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 205
Query: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225
W I++++ LP++GWNC S CS + P + Y++F V ++LLL IV Y I
Sbjct: 206 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 265
Query: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271
+ + R+ R K+I + K + L KT++++L V I CW P
Sbjct: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325
Query: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
L +++ DV K+ K +F + +L +LNS NPIIY L +K++R AF + C+
Sbjct: 326 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 383
>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
Length = 330
Score = 126 bits (317), Expect = 3e-29
Identities = 84/290 (28%), Positives = 150/290 (51%), Gaps = 17/290 (5%)
Query: 44 SIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLL 103
S K VV + + EN V+ I T F PM+ +G+LA++DLLAG+ L+
Sbjct: 39 SPKAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLG----LV 94
Query: 104 LSGATTYKLTPAQWFL-REGSMFVALSASVFSLLAIAIERYITMLK-MKLHNGSNNFRLF 161
L A + + A+ L G + +A +AS+ SLLAI ++RY+++ + ++ + R +
Sbjct: 95 LHFAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTY 154
Query: 162 LLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILY 221
++++ W +L LG LP++ WNC+ L++C V PL H ++ F + + ++ LY
Sbjct: 155 VMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGI-MLQLY 213
Query: 222 CRIYSLVRTRSRRLTFRKNISKASR--SSEKSLALLKTVIIVLSVFIACWAPLFILLLLD 279
+I +V ++++ ++++ AS ++ K +A T+ +VL F ACW P + LL
Sbjct: 214 AQICRIVCRHAQQIALQRHLLPASHYVATRKGIA---TLAVVLGAFAACWLPFTVYCLLG 270
Query: 280 VGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCC 329
L L+ A NS NPIIY N+++++ + CC
Sbjct: 271 DAHSPPLYTYL-----TLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCC 315
>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
Length = 334
Score = 124 bits (312), Expect = 1e-28
Identities = 88/300 (29%), Positives = 147/300 (49%), Gaps = 26/300 (8%)
Query: 53 ILICC---FIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATT 109
I++C I EN V+L I+ PM+ IG+LAL+DLLAG+ N + +
Sbjct: 49 IVLCTSGTLISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFAYLLQ 108
Query: 110 YKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITML-KMKLHNGSNNFRLFLLISACW 168
+ T + G + + SASV SLLAI ++RY+++ + H+ ++++ W
Sbjct: 109 SEATK---LVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLW 165
Query: 169 VISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLV 228
S+ LG LP+MGWNC+ S+CS V PL K+ + F + ++ LY +I +V
Sbjct: 166 GTSICLGLLPVMGWNCLRDESTCSVVRPL-TKNNAAILSVSFLFMFALMLQLYIQICKIV 224
Query: 229 RTRSRRLTFRKNISKASR--SSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKT 286
+ ++ + + S ++ K ++ T+ I+L F ACW P + L+
Sbjct: 225 MRHAHQIALQHHFLATSHYVTTRKGVS---TLAIILGTFAACWMPFTLYSLI-------- 273
Query: 287 CDILFRAEY---FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRP 343
D + + Y L+ A NS NP+IY N+E+++A I CC C A + + P
Sbjct: 274 ADYTYPSIYTYATLLPATYNSIINPVIYAFRNQEIQKALCLI--CCGCIPSSLAQRARSP 331
>gi|119508433 melanocortin 4 receptor [Homo sapiens]
Length = 332
Score = 121 bits (303), Expect = 1e-27
Identities = 84/287 (29%), Positives = 145/287 (50%), Gaps = 26/287 (9%)
Query: 51 VFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTY 110
VF+ + +LENI V++ I K K H PMY+FI +LA++D+L V+ + ++
Sbjct: 50 VFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNS 109
Query: 111 KLTPAQWF------LREGSMFVALSASVFSLLAIAIERYITML-KMKLHNGSNNFRLFLL 163
T AQ F + + + +L AS+ SLL+IA++RY T+ ++ HN R+ ++
Sbjct: 110 TDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGII 169
Query: 164 ISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCR 223
IS W + G L I+ S S V+ I T FT+L L + LY
Sbjct: 170 ISCIWAACTVSGILFII-------YSDSSAVI-------ICLITMFFTMLAL-MASLYVH 214
Query: 224 IYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCK 283
++ + R +R+ + + A+ T+ I++ VF+ CWAP F+ L+ + C
Sbjct: 215 MFLMARLHIKRIAVLPGTGAIRQGANMKGAI--TLTILIGVFVVCWAPFFLHLIFYISCP 272
Query: 284 VKTCDILFRAEY--FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSC 328
+ F + + +L+L + NS +P+IY L ++E+R+ F I+ C
Sbjct: 273 QNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICC 319
>gi|5174535 melanocortin 5 receptor [Homo sapiens]
Length = 325
Score = 117 bits (294), Expect = 1e-26
Identities = 84/290 (28%), Positives = 143/290 (49%), Gaps = 31/290 (10%)
Query: 51 VFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTY 110
VF+ + +LENI V+ I K K H PMY+F+ +LA++D+L ++ +
Sbjct: 42 VFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNN 101
Query: 111 K-LTPAQWFLR------EGSMFVALSASVFSLLAIAIERYITML-KMKLHNGSNNFRLFL 162
K L A F+R + + +++ AS+ SLLAIA++RY+T+ ++ H+ R
Sbjct: 102 KHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGA 161
Query: 163 LISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKH-YILFC-TTVFTLLLLSIVIL 220
+I+ W + C V LY + Y++ C ++F +L +V L
Sbjct: 162 IIAGIWAF-----------------CTGCGIVFILYSESTYVILCLISMFFAMLFLLVSL 204
Query: 221 YCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV 280
Y ++ L RT +R+ S A + + A+ TV ++L VF CWAP F+ L L +
Sbjct: 205 YIHMFLLARTHVKRIAALPGASSARQRTSMQGAV--TVTMLLGVFTVCWAPFFLHLTLML 262
Query: 281 GCKVKTCDILFRAEY--FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSC 328
C F + + +L+L + NS +P+IY ++EMR+ F I+ C
Sbjct: 263 SCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICC 312
>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
Length = 362
Score = 114 bits (286), Expect = 1e-25
Identities = 86/283 (30%), Positives = 141/283 (49%), Gaps = 18/283 (6%)
Query: 53 ILICC---FIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATT 109
+L+C I EN V+ I T PM+ +G+LA +DLLAG L+L
Sbjct: 77 VLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAG----CGLILHFVFQ 132
Query: 110 YKLTPAQW--FLREGSMFVALSASVFSLLAIAIERYITMLK-MKLHNGSNNFRLFLLISA 166
Y L P++ L G + + +ASV SLLAI ++RY+++ + ++ + LL++A
Sbjct: 133 Y-LVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAA 191
Query: 167 CWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYS 226
W +SL LG LP++GWNC++ ++CS V PL H L + F ++ ++ LY RI
Sbjct: 192 TWTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALL-SAAFFMVFGIMLHLYVRICQ 250
Query: 227 LVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKT 286
+V + ++ +++ + + T+ +VL F A W P I + VG
Sbjct: 251 VVWRHAHQIALQQHCLAPPHLAATRKG-VGTLAVVLGTFGASWLPFAIYCV--VGSHEDP 307
Query: 287 CDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCC 329
+ L+ A NS NPIIY N+E++RA ++ C
Sbjct: 308 AVYTYAT---LLPATYNSMINPIIYAFRNQEIQRALWLLLCGC 347
>gi|170671732 melanocortin 3 receptor [Homo sapiens]
Length = 323
Score = 111 bits (278), Expect = 9e-25
Identities = 79/291 (27%), Positives = 139/291 (47%), Gaps = 29/291 (9%)
Query: 51 VFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYT-ANLLLSGATT 109
VF+ + +LENI V+L + + H PMY+F+ +LA++D+L V+ ++++ +
Sbjct: 44 VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHS 103
Query: 110 YKLTPAQWFLR------EGSMFVALSASVFSLLAIAIERYITML-KMKLHNGSNNFRLFL 162
LT F++ + + ++L AS+ +LLAIA++RY+T+ ++ H+ +
Sbjct: 104 DYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALT 163
Query: 163 LISACWVISLILGGLPIMGWNCISALSSCSTVLPLY--HKHYILFCTTVFTLLLLSIVIL 220
LI A WV C V +Y K I+ T+F ++L + L
Sbjct: 164 LIVAIWV-----------------CCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTL 206
Query: 221 YCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDV 280
Y ++ R +R+ + + T+ I+L VFI CWAP F+ L+L +
Sbjct: 207 YVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLII 266
Query: 281 GCKVKTCDILFRAEY--FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCC 329
C I + A + +LVL + NS +P+IY + E+R F I+ C
Sbjct: 267 TCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGC 317
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 109 bits (273), Expect = 4e-24
Identities = 99/371 (26%), Positives = 164/371 (44%), Gaps = 59/371 (15%)
Query: 36 NISADK-----ENSIKLTSVVFILICCFIILENIFVLLTI-WKTKKFHRPMYYFIGNLAL 89
N+S+++ E + LT + +++ IL N+ V++ + W + YFI +LA
Sbjct: 7 NVSSEEGFGSVEKVVLLTFLSTVILMA--ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAF 64
Query: 90 SDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALS-------ASVFSLLAIAIER 142
+DLL V L+ +L W E V S AS+F L I+++R
Sbjct: 65 ADLLVSV------LVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDR 118
Query: 143 YITMLKMKL--HNGSNNFRLFLLISACWVISLILGGLPIM-GWNCISAL----------- 188
Y + L N R+ L++ CWVI + LPIM GWN I +
Sbjct: 119 YYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN 178
Query: 189 SSCSTVLPLYHKHYILFCTTV-FTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRS 247
S+ + + + +K Y + C+ V F + L +V+ Y RIY + + ++ + +S S
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 248 SEKSL------------ALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY 295
+S KT+ I++ F CWAP F+ ++D ++ A
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA-- 296
Query: 296 FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAG--MEFSRS 353
FL L +NSG NP +Y NK RRAF+ I+ C +++RP I G + S +
Sbjct: 297 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC-------DDERYRRPSILGQTVPCSTT 349
Query: 354 KSDNSSHPQKD 364
+ S+H +D
Sbjct: 350 TINGSTHVLRD 360
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 108 bits (269), Expect = 1e-23
Identities = 95/352 (26%), Positives = 155/352 (44%), Gaps = 57/352 (16%)
Query: 36 NISADK-----ENSIKLTSVVFILICCFIILENIFVLLTI-WKTKKFHRPMYYFIGNLAL 89
N+S+++ E + LT + +++ IL N+ V++ + W + YFI +LA
Sbjct: 7 NVSSEEGFGSVEKVVLLTFLSTVILMA--ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAF 64
Query: 90 SDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALS-------ASVFSLLAIAIER 142
+DLL V L+ +L W E V S AS+F L I+++R
Sbjct: 65 ADLLVSV------LVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDR 118
Query: 143 YITMLKMKL--HNGSNNFRLFLLISACWVISLILGGLPIM-GWNCISAL----------- 188
Y + L N R+ L++ CWVI + LPIM GWN I +
Sbjct: 119 YYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN 178
Query: 189 SSCSTVLPLYHKHYILFCTTV-FTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRS 247
S+ + + + +K Y + C+ V F + L +V+ Y RIY + + ++ + +S S
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 248 SEKSL------------ALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY 295
+S KT+ I++ F CWAP F+ ++D ++ A
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA-- 296
Query: 296 FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAG 347
FL L +NSG NP +Y NK RRAF+ I+ C +++RP I G
Sbjct: 297 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC-------DDERYRRPSILG 341
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 108 bits (269), Expect = 1e-23
Identities = 95/352 (26%), Positives = 155/352 (44%), Gaps = 57/352 (16%)
Query: 36 NISADK-----ENSIKLTSVVFILICCFIILENIFVLLTI-WKTKKFHRPMYYFIGNLAL 89
N+S+++ E + LT + +++ IL N+ V++ + W + YFI +LA
Sbjct: 7 NVSSEEGFGSVEKVVLLTFLSTVILMA--ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAF 64
Query: 90 SDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALS-------ASVFSLLAIAIER 142
+DLL V L+ +L W E V S AS+F L I+++R
Sbjct: 65 ADLLVSV------LVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDR 118
Query: 143 YITMLKMKL--HNGSNNFRLFLLISACWVISLILGGLPIM-GWNCISAL----------- 188
Y + L N R+ L++ CWVI + LPIM GWN I +
Sbjct: 119 YYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN 178
Query: 189 SSCSTVLPLYHKHYILFCTTV-FTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRS 247
S+ + + + +K Y + C+ V F + L +V+ Y RIY + + ++ + +S S
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 248 SEKSL------------ALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY 295
+S KT+ I++ F CWAP F+ ++D ++ A
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA-- 296
Query: 296 FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAG 347
FL L +NSG NP +Y NK RRAF+ I+ C +++RP I G
Sbjct: 297 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC-------DDERYRRPSILG 341
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 108 bits (269), Expect = 1e-23
Identities = 95/352 (26%), Positives = 155/352 (44%), Gaps = 57/352 (16%)
Query: 36 NISADK-----ENSIKLTSVVFILICCFIILENIFVLLTI-WKTKKFHRPMYYFIGNLAL 89
N+S+++ E + LT + +++ IL N+ V++ + W + YFI +LA
Sbjct: 7 NVSSEEGFGSVEKVVLLTFLSTVILMA--ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAF 64
Query: 90 SDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALS-------ASVFSLLAIAIER 142
+DLL V L+ +L W E V S AS+F L I+++R
Sbjct: 65 ADLLVSV------LVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDR 118
Query: 143 YITMLKMKL--HNGSNNFRLFLLISACWVISLILGGLPIM-GWNCISAL----------- 188
Y + L N R+ L++ CWVI + LPIM GWN I +
Sbjct: 119 YYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN 178
Query: 189 SSCSTVLPLYHKHYILFCTTV-FTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRS 247
S+ + + + +K Y + C+ V F + L +V+ Y RIY + + ++ + +S S
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 248 SEKSL------------ALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY 295
+S KT+ I++ F CWAP F+ ++D ++ A
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA-- 296
Query: 296 FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAG 347
FL L +NSG NP +Y NK RRAF+ I+ C +++RP I G
Sbjct: 297 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC-------DDERYRRPSILG 341
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 108 bits (269), Expect = 1e-23
Identities = 95/352 (26%), Positives = 155/352 (44%), Gaps = 57/352 (16%)
Query: 36 NISADK-----ENSIKLTSVVFILICCFIILENIFVLLTI-WKTKKFHRPMYYFIGNLAL 89
N+S+++ E + LT + +++ IL N+ V++ + W + YFI +LA
Sbjct: 7 NVSSEEGFGSVEKVVLLTFLSTVILMA--ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAF 64
Query: 90 SDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALS-------ASVFSLLAIAIER 142
+DLL V L+ +L W E V S AS+F L I+++R
Sbjct: 65 ADLLVSV------LVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDR 118
Query: 143 YITMLKMKL--HNGSNNFRLFLLISACWVISLILGGLPIM-GWNCISAL----------- 188
Y + L N R+ L++ CWVI + LPIM GWN I +
Sbjct: 119 YYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN 178
Query: 189 SSCSTVLPLYHKHYILFCTTV-FTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRS 247
S+ + + + +K Y + C+ V F + L +V+ Y RIY + + ++ + +S S
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 248 SEKSL------------ALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY 295
+S KT+ I++ F CWAP F+ ++D ++ A
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA-- 296
Query: 296 FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAG 347
FL L +NSG NP +Y NK RRAF+ I+ C +++RP I G
Sbjct: 297 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC-------DDERYRRPSILG 341
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 108 bits (269), Expect = 1e-23
Identities = 95/352 (26%), Positives = 155/352 (44%), Gaps = 57/352 (16%)
Query: 36 NISADK-----ENSIKLTSVVFILICCFIILENIFVLLTI-WKTKKFHRPMYYFIGNLAL 89
N+S+++ E + LT + +++ IL N+ V++ + W + YFI +LA
Sbjct: 7 NVSSEEGFGSVEKVVLLTFLSTVILMA--ILGNLLVMVAVCWDRQLRKIKTNYFIVSLAF 64
Query: 90 SDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALS-------ASVFSLLAIAIER 142
+DLL V L+ +L W E V S AS+F L I+++R
Sbjct: 65 ADLLVSV------LVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDR 118
Query: 143 YITMLKMKL--HNGSNNFRLFLLISACWVISLILGGLPIM-GWNCISAL----------- 188
Y + L N R+ L++ CWVI + LPIM GWN I +
Sbjct: 119 YYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQN 178
Query: 189 SSCSTVLPLYHKHYILFCTTV-FTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRS 247
S+ + + + +K Y + C+ V F + L +V+ Y RIY + + ++ + +S S
Sbjct: 179 SNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSES 238
Query: 248 SEKSL------------ALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEY 295
+S KT+ I++ F CWAP F+ ++D ++ A
Sbjct: 239 RPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA-- 296
Query: 296 FLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAG 347
FL L +NSG NP +Y NK RRAF+ I+ C +++RP I G
Sbjct: 297 FLWLGYINSGLNPFLYAFLNKSFRRAFLIILCC-------DDERYRRPSILG 341
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 105 bits (262), Expect = 7e-23
Identities = 113/414 (27%), Positives = 188/414 (45%), Gaps = 83/414 (20%)
Query: 26 VRHYNYTGKLNISAD---------KENSIKLTSVVFILICCFIILENIFVLLTIWKTKKF 76
+++ N+TG S++ + S+ L FIL F I+ NI V+L++ +
Sbjct: 20 LKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFIL---FAIVGNILVILSVACNRHL 76
Query: 77 HRPMYYFIGNLALSDLLAG---VAYTANLLLSGATTYKLTPAQWFLREGSMF-------- 125
P YFI NLA++DLL + ++A L + G W L G +F
Sbjct: 77 RTPTNYFIVNLAMADLLLSFTVLPFSAALEVLG---------YWVL--GRIFCDIWAAVD 125
Query: 126 -VALSASVFSLLAIAIERYITM-LKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWN 183
+ +AS+ SL AI+I+RYI + ++ + L + + WV+S ++ P++GW
Sbjct: 126 VLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWK 185
Query: 184 CISALSSCSTVLPLYHKHYILFCTT-VFTLLLLSIVILYCRIYSLVR------------- 229
A + Y LF + F + L I+++YCR+Y + +
Sbjct: 186 -EPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKE 244
Query: 230 -TRSRRLTFR---KNISKASRSSEK--------SLAL-----------LKTVIIVLSVFI 266
+ S+ LT R KN + + SS K S+A+ KT+ IV+ +FI
Sbjct: 245 MSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFI 304
Query: 267 ACWAPLFILLLL-DVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRI 325
CW P FI L L + +K D +F+ ++L NS NPIIY ++KE +RAF+RI
Sbjct: 305 LCWLPFFIALPLGSLFSTLKPPDAVFKVVFWL--GYFNSCLNPIIYPCSSKEFKRAFVRI 362
Query: 326 MSCCKCPSGDSAGKFKRPIIAGMEF-----SRSKSDNSSHPQKDEGDNPETIMS 374
+ C+C + +R + G + +R S S +KD D+ + +S
Sbjct: 363 LG-CQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLS 415
>gi|5921992 adenosine A2a receptor [Homo sapiens]
Length = 412
Score = 105 bits (261), Expect = 9e-23
Identities = 84/302 (27%), Positives = 138/302 (45%), Gaps = 36/302 (11%)
Query: 51 VFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTY 110
V + I IL N+ V +W YF+ +LA +D+ GV A +
Sbjct: 12 VELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVL---------AIPF 62
Query: 111 KLTPAQWFLR--EGSMFVAL------SASVFSLLAIAIERYITMLKMKLHNGS-NNFRLF 161
+T + F G +F+A +S+FSLLAIAI+RYI + +NG R
Sbjct: 63 AITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAK 122
Query: 162 LLISACWVISLILGGLPIMGWN--------------CISALSSC--STVLPLYHKHYILF 205
+I+ CWV+S +G P++GWN C +C V+P+ + Y F
Sbjct: 123 GIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNF 182
Query: 206 CTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSS-EKSLALLKTVIIVLSV 264
V LLL + + Y RI+ R + +++ + + +RS+ +K + K++ I++ +
Sbjct: 183 FACVLVPLLLMLGV-YLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGL 241
Query: 265 FIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIR 324
F CW PL I+ C + L+ +VL+ NS NP IY +E R+ F +
Sbjct: 242 FALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRK 301
Query: 325 IM 326
I+
Sbjct: 302 II 303
>gi|4505127 melanocortin 2 receptor [Homo sapiens]
Length = 297
Score = 104 bits (259), Expect = 2e-22
Identities = 86/298 (28%), Positives = 144/298 (48%), Gaps = 38/298 (12%)
Query: 45 IKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGV-AYTANLL 103
+ L +F I +LEN+ VLL ++K K PMY+FI +LA+SD+L + N+L
Sbjct: 24 VVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENIL 83
Query: 104 LSGATTYKLTPAQWFLREG-----SMFV-ALSASVFSLLAIAIERYITML-KMKLHNGSN 156
+ L P F S+FV +L S+FSL IA +RYIT+ ++ H+
Sbjct: 84 IILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVT 143
Query: 157 NFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLS 216
R ++++ W G + V+ +H ++ T++F L+L+
Sbjct: 144 MRRTVVVLTVIWTFCTGTG---------------ITMVIFSHHVPTVITFTSLFPLMLVF 188
Query: 217 IVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILL 276
I+ LY ++ L R+ +R+ IS R++ K T+ I+L VFI CWAP + +
Sbjct: 189 ILCLYVHMFLLARSHTRK------ISTLPRANMKGAI---TLTILLGVFIFCWAPFVLHV 239
Query: 277 LLDVGCKVK---TCDI-LFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
LL C C + LF+ L++ N+ +P IY + E+R AF +++ C +
Sbjct: 240 LLMTFCPSNPYCACYMSLFQVNGMLIMC--NAVIDPFIYAFRSPELRDAFKKMIFCSR 295
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.138 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,379,193
Number of Sequences: 37866
Number of extensions: 471159
Number of successful extensions: 3219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 470
Number of HSP's successfully gapped in prelim test: 244
Number of HSP's that attempted gapping in prelim test: 1787
Number of HSP's gapped (non-prelim): 931
length of query: 382
length of database: 18,247,518
effective HSP length: 104
effective length of query: 278
effective length of database: 14,309,454
effective search space: 3978028212
effective search space used: 3978028212
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.