Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 13027602
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13027602 DDRGK domain containing 1 [Homo sapiens]
(314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13027602 DDRGK domain containing 1 [Homo sapiens] 605 e-173
gi|148746195 trichohyalin [Homo sapiens] 67 2e-11
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 66 3e-11
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 66 3e-11
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 66 5e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 64 1e-10
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 64 2e-10
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 63 3e-10
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 63 4e-10
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 63 4e-10
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 63 4e-10
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 63 4e-10
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 63 4e-10
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 62 5e-10
gi|92859701 myosin VI [Homo sapiens] 62 7e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 9e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 62 9e-10
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 62 9e-10
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 61 1e-09
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 60 2e-09
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 60 2e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 60 3e-09
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 59 6e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 59 7e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 59 7e-09
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 58 1e-08
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 58 1e-08
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 57 2e-08
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 57 2e-08
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 57 2e-08
>gi|13027602 DDRGK domain containing 1 [Homo sapiens]
Length = 314
Score = 605 bits (1560), Expect = e-173
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MVAPVWYLVAAALLVGFILFLTRSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRA 60
MVAPVWYLVAAALLVGFILFLTRSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRA
Sbjct: 1 MVAPVWYLVAAALLVGFILFLTRSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRA 60
Query: 61 GGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAK 120
GGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAK
Sbjct: 61 GGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAK 120
Query: 121 KLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREE 180
KLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREE
Sbjct: 121 KLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREE 180
Query: 181 QAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGL 240
QAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGL
Sbjct: 181 QAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGL 240
Query: 241 RTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNS 300
RTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNS
Sbjct: 241 RTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNS 300
Query: 301 LIAWGRESPAQAPA 314
LIAWGRESPAQAPA
Sbjct: 301 LIAWGRESPAQAPA 314
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 67.4 bits (163), Expect = 2e-11
Identities = 52/198 (26%), Positives = 101/198 (51%), Gaps = 14/198 (7%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENE---EEAVILAQEEEGVEKPAETHLSGKIGAKKL 122
RR+ + Q +R Q + E +E E E V+ +EE+ E+ + + ++L
Sbjct: 219 RRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 123 RKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERK-----A 177
RKLE ++ R+ ++E E ++++RL +++ K+EEER +EE++E++ER+
Sbjct: 279 RKLERQELRRERQE----EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 178 REEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQ 237
RE+Q +RE EE + + EEE + + EQ + + + ++ ++ + L +
Sbjct: 335 REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLR--REQQLRREQQLRRE 392
Query: 238 VGLRTQDTINRIQDLLAE 255
LR + + R Q L E
Sbjct: 393 QQLRREQQLRREQQLRRE 410
Score = 63.9 bits (154), Expect = 2e-10
Identities = 61/214 (28%), Positives = 97/214 (45%), Gaps = 33/214 (15%)
Query: 25 RGRAASAGQEPLHNE---ELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQ 81
RGR + + PL + +L R + PEE R R+RR+ LQ +
Sbjct: 779 RGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838
Query: 82 RVAWAEADENEEEAVILAQEEEGVEKPAETHLSG--KIGAKKLRKLEEKQARKA------ 133
++ + E A L +EE+G+++ E S + K +LEE++ R+
Sbjct: 839 QL------QRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
Query: 134 --------------QREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE 179
Q E EE +REER++ Q + +EEE+L+ EEEQ EER+ R
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRR 952
Query: 180 EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
Q +RE +Y K K+ EE+ +GE + + Q
Sbjct: 953 RQ-ERE-RQYRKDKKLQQKEEQLLGEEPEKRRRQ 984
Score = 60.5 bits (145), Expect = 2e-09
Identities = 39/144 (27%), Positives = 74/144 (51%), Gaps = 25/144 (17%)
Query: 67 RRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG----VEKPAETHLSGKIGAKKL 122
+R+ RL+ +RR QR+ + ++ E +L +EEE +++ E L ++ +++
Sbjct: 551 KREEEKRLEQERREQRL---KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEV 607
Query: 123 RKLEEKQARKAQREAEEAEREERKRL------------------ESQREAEWKKEEERLR 164
+LE+++ R+ + + EE E E R++L + +RE K+EEE R
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 165 LEEEQKEEEERKAREEQAQREHEE 188
LE+ K E E + RE++ E +E
Sbjct: 668 LEQRLKREHEEERREQELAEEEQE 691
Score = 58.2 bits (139), Expect = 1e-08
Identities = 41/158 (25%), Positives = 82/158 (51%), Gaps = 6/158 (3%)
Query: 33 QEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWA-EADEN 91
Q+ + EE R + + EE P+R+R+L + R+ +R E E
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 92 EEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQ 151
E++ L +E++ K E + ++ R+ +E++ ++ +R ++ RE+ +R E Q
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQ---EERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 152 --REAEWKKEEERLRLEEEQKEEEERKAREEQAQREHE 187
RE E ++ E++LR E+E++ E++ RE+Q +RE +
Sbjct: 351 LRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/152 (26%), Positives = 77/152 (50%), Gaps = 13/152 (8%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE R + RR R Q + R ++ E +E E+ + QEEE E+
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEE 370
Query: 116 KIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQ--------REAEWKKEEERLRLEE 167
+ ++LR+ ++ + + R ++ RE++ R E Q RE + ++E++ R +E
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 168 EQKEEE--ERKAREEQAQREHEE---YLKLKE 194
E++ E+ E++ RE++ +RE EE +LK +E
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREE 462
Score = 56.2 bits (134), Expect = 4e-08
Identities = 43/159 (27%), Positives = 85/159 (53%), Gaps = 11/159 (6%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKK---L 122
+R++ RLQ + R+++ E +E E+ + +E+ ++ E L + ++ L
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLL 579
Query: 123 RKLEEKQARKAQREAEEA-----EREERKRLESQ--REAEWKKEE-ERLRLEEEQKEEEE 174
++ EE++ ++ +RE EE +REE +RLE + RE K+EE E R ++ K EE+
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 175 RKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
+ R++Q +RE +E + + EEE + + + E +
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE 678
Score = 55.8 bits (133), Expect = 5e-08
Identities = 47/152 (30%), Positives = 77/152 (50%), Gaps = 6/152 (3%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE + RR++ L + +RR + + E + E++ Q E+ E L
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 116 KIGAKKL--RKLEEKQARKAQREAEEA--EREERKRLESQ-REAEWKKEEERLRLEEEQK 170
+ ++L R E+Q R+ Q E E +REE KRLE + RE K+E+E R + ++
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Query: 171 EEEERKAREEQAQREH-EEYLKLKEAFVVEEE 201
EEE R+ R ++ Q E E+ LK +E +E+E
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQE 613
Score = 55.8 bits (133), Expect = 5e-08
Identities = 49/168 (29%), Positives = 85/168 (50%), Gaps = 17/168 (10%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE R + RR + L R Q +RR QR+ E +E ++ + Q+ ++ L
Sbjct: 493 EEERREQQERREQQL-RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 116 KIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKE-----EERLRLEE-EQ 169
+ K+L +E++ ++ +RE EE + KR E +R+ K+E E+RL+ EE E+
Sbjct: 552 REEEKRLE--QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609
Query: 170 KEEEERK----AREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E+EER+ REE + ++ LK +E +EE + + EQ +
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEE----QEERRQQQLRREQQE 653
Score = 55.8 bits (133), Expect = 5e-08
Identities = 53/203 (26%), Positives = 100/203 (49%), Gaps = 15/203 (7%)
Query: 23 RSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGS-RLQAQRRAQ 81
+ R R ++ L +EL R + E E+ + + R R+ L +L+ +R Q
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 82 RVAWAEADENEEEAVILAQEEEGVE-KPAETHLSGKIGAKKLRKLEEKQARKAQR----- 135
++ E D E L QE E + + E+ + + ++ EE+Q R QR
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822
Query: 136 -EAEEAEREER-KRLESQREAEWKKEE-----ERLRLEEEQK-EEEERKAREEQAQREHE 187
E E+ + EE+ +RL +R+ +++ EE E+ R EE++ +EEE+K R+E+ ++ E
Sbjct: 1823 WEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 188 EYLKLKEAFVVEEEGVGETMTEE 210
E+++ ++ VGE ++E
Sbjct: 1883 EHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 55.5 bits (132), Expect = 6e-08
Identities = 48/159 (30%), Positives = 78/159 (49%), Gaps = 14/159 (8%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADEN--EEEAVILAQEEEGVEKPAETHL 113
++ R R R+RRD + QR W E +E EEE + + E E P E L
Sbjct: 157 KQERLEQRDRQRRD------EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 114 SGKIGAKKLRK-LEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEE 172
+ + RK EEKQ ++ +R+ + EE K +RE +KEEE+L+ EE Q++
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWR-KRETVLRKEEEKLQEEEPQRQR 269
Query: 173 EERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQ 211
E ++ E+ + E +E + ++ EEE + + EQ
Sbjct: 270 ELQEEEEQLRKLERQELRRERQ----EEEQQQQRLRREQ 304
Score = 55.1 bits (131), Expect = 8e-08
Identities = 47/199 (23%), Positives = 94/199 (47%), Gaps = 23/199 (11%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E +E R R R+ R+ LQ Q+R QR + + D+ + E+E + + +
Sbjct: 1186 EEQEKRRQERERQYRE-EEELQRQKRKQR--YRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242
Query: 114 SGKIGAKKLRKLEEKQARKAQR---------EAEEAEREERKRLESQREAEWKKEEERLR 164
G+ ++ R+LE+ Q R Q E +E +RE+ +R QR+ + +EE+ R
Sbjct: 1243 KGREN-EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Query: 165 LEEEQKEEEERKA----------REEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
E+++ + +RK+ REE+ +R+ + +E +++E +E+ +
Sbjct: 1302 EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRK 1361
Query: 215 FLTEFINYIKQSKVVLLED 233
F E + + +Q + L E+
Sbjct: 1362 FREEELRHQEQGRKFLEEE 1380
Score = 55.1 bits (131), Expect = 8e-08
Identities = 45/166 (27%), Positives = 82/166 (49%), Gaps = 19/166 (11%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRK 124
+R R Q +R Q+ A +++EE +L +E E + ET + + L++
Sbjct: 1288 QRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347
Query: 125 LEEKQARKAQREAEEAER------------EERKRLESQ-REAEWKKEEERLRLEEEQ-- 169
EE+ R+ +R+ + E EE +RL Q RE ++ KEE++LR +E +
Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Query: 170 -KEEEERKAREEQAQ---REHEEYLKLKEAFVVEEEGVGETMTEEQ 211
+++ +RK REE+ Q +E + + +E V +E + + EEQ
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Score = 54.7 bits (130), Expect = 1e-07
Identities = 46/173 (26%), Positives = 88/173 (50%), Gaps = 13/173 (7%)
Query: 33 QEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAW----AEA 88
+E L E A + + G E +E R RR + +L+ +R+ +R A
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ 896
Query: 89 DENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRL 148
++ +E +L +EEE +++ + ++ R EE+Q ++ + + ERE+R+R
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR--EEEQLQQEEEQLLREEREKRRRQ 954
Query: 149 ESQR----EAEWKKEEERLRLEEEQK---EEEERKAREEQAQREHEEYLKLKE 194
E +R + + +++EE+L EE +K +E E+K REE+ ++ EE L +E
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/155 (25%), Positives = 76/155 (49%), Gaps = 6/155 (3%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETH 112
L+ EE R + R Q Q+ +++ E ++ + ++ + E
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 113 LSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKE---EERLRLEEEQ 169
L G+ K+ R+ EK+ R+ + +E E+ R+ E +R EW+++ ++ L+ EEEQ
Sbjct: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
Query: 170 ---KEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
+E E+R+ +E + Q EE L+ +E ++ EE
Sbjct: 1033 LLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/149 (26%), Positives = 78/149 (52%), Gaps = 12/149 (8%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKL 125
+R + R + +RR Q++ + +E E + L +EE ++ + R+
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQ-------QLRREQ 511
Query: 126 EEKQARKAQREAEEAEREERKRLESQ-REAEWKKEEERLRLEEEQKEEEERKAREEQAQR 184
EE++ ++ +R+ EE ++R R E Q R + ++ E+ L+ EEE++ E+ER RE++ +R
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER--REQRLKR 569
Query: 185 EHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E EE + + EEE + + EQ +
Sbjct: 570 EQEE--RRDQLLKREEERRQQRLKREQEE 596
Score = 52.8 bits (125), Expect = 4e-07
Identities = 60/225 (26%), Positives = 100/225 (44%), Gaps = 31/225 (13%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPA---- 109
E +E R RR + L R Q +RR Q++ + +E E+ + QEEE E+
Sbjct: 323 EQQERREQQEERREQQL-RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 110 ----------------ETHLSGKIGAKKLRKLE-EKQARKAQ---REAEEAEREERKRLE 149
E L + ++ ++L E+Q R+ Q RE EE R E+K +
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE-RHEQKHEQ 440
Query: 150 SQREAEWKKEEERLR---LEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGET 206
+RE K+E+E R EE+ E E++ R++Q +R+ EE + +E ++ EE
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEE--ERRERWLKLEEEERRE 498
Query: 207 MTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQD 251
E + Q E +Q E+ Q LR++ + R Q+
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Score = 52.8 bits (125), Expect = 4e-07
Identities = 41/173 (23%), Positives = 88/173 (50%), Gaps = 12/173 (6%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E ++ R R R+ R+ +L+ Q R ++ E +E +EEE + + E
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739
Query: 114 SGKIGAKKLRKLEEKQARKAQREAEEAEREER-KRLESQREAEWKKEEERLRLEEE---- 168
+ ++ RK+ E++ + +RE ++ R+ER ++ + + ++EE++LR +E
Sbjct: 1740 LRR--QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF 1797
Query: 169 QKEEEERKAREEQAQREHE---EYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
++EE+ R+ REEQ R + +Y +E +EE+ + + +E+ + + E
Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQ--EQRLRQERDRQYRAE 1848
Score = 52.4 bits (124), Expect = 5e-07
Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 19/165 (11%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETH 112
L+ EEP RR++ L S Q +RR Q++ E E E+ + +EEE +E+ +
Sbjct: 620 LKREEPE---EERRQQLLKSEEQEERRQQQLR-REQQERREQRLKREEEEERLEQRLKRE 675
Query: 113 LSGKIGAKKLRKLEEKQARKA----------QREAEEAEREER-----KRLESQREAEWK 157
+ ++L + E++QAR+ Q E+E R+ + ++ E QR + +
Sbjct: 676 HEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ 735
Query: 158 KEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEG 202
+E+ R R E Q +EEER R++Q + + ++ +A E G
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERG 780
Score = 52.4 bits (124), Expect = 5e-07
Identities = 45/159 (28%), Positives = 78/159 (49%), Gaps = 20/159 (12%)
Query: 74 LQAQRRAQRVAWAEADENEEEAVILAQEEE---GVEKPAETHLSGKIGAKKLRKLEEKQA 130
L+ +R +R+ E EEE L QEEE G E+ + +K +L++++
Sbjct: 1034 LREEREKRRLQERERQYREEEE--LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE 1091
Query: 131 RKAQREAEEAEREERKRLESQREAEWKKEEERL-----------RLEEEQKEEEERKARE 179
+ + E E+ R+ER+R + + E E ++EEE+L LE + +EEEE + E
Sbjct: 1092 QLLREEPEKRRRQERER-QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 180 EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
EQ RE E + +E +E + E +++ + L E
Sbjct: 1151 EQLLREEPEKRRRQE---LERQYREEEELQQEEEQLLRE 1186
Score = 52.0 bits (123), Expect = 7e-07
Identities = 51/191 (26%), Positives = 81/191 (42%), Gaps = 36/191 (18%)
Query: 56 EEPRAGGRPRRRR---DLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETH 112
EE + PR R+ + G R + +R+ Q AE +E E+ L Q +
Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 113 LSGKIGAKKLRKLEEKQ--------------------------ARKAQREAEEAEREERK 146
+ ++ R+ EE+Q RK + E ++ RE +
Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Query: 147 RL-ESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGE 205
R+ + + E EW+K E LR EEE+ +EEE + R+ + Q E E+ KL+ +E E
Sbjct: 236 RVFQEEEEKEWRKRETVLRKEEEKLQEEEPQ-RQRELQEEEEQLRKLE-----RQELRRE 289
Query: 206 TMTEEQSQSFL 216
EEQ Q L
Sbjct: 290 RQEEEQQQQRL 300
Score = 52.0 bits (123), Expect = 7e-07
Identities = 44/199 (22%), Positives = 93/199 (46%), Gaps = 18/199 (9%)
Query: 33 QEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENE 92
Q+ ++L ++ + L E+ + RR R Q RR Q++ + +E
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 93 EEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAER---------E 143
E+ + E+ +++ E ++ + E+++ ++ + +E ER E
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEE 494
Query: 144 ERKRLESQREAEWKKE-----EERLRLEEEQKEEEERKAREEQAQREHEE----YLKLKE 194
ER+ + +RE + ++E E+RL+ +EE++ ++R E+Q +RE EE LK +E
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 195 AFVVEEEGVGETMTEEQSQ 213
+E+E + + EQ +
Sbjct: 555 EKRLEQERREQRLKREQEE 573
Score = 51.6 bits (122), Expect = 9e-07
Identities = 46/192 (23%), Positives = 88/192 (45%), Gaps = 8/192 (4%)
Query: 25 RGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVA 84
R R +E L E R Q + + R + RR+++ R Q + R ++
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326
Query: 85 WAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ-REAEEAERE 143
E E E + ++EE E+ + ++LR+ +E++ R+ Q R ++ RE
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 144 ERKRLESQ--REAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
++ R E Q RE + ++E++ L EQ+ E++ R EQ R +E + ++ E+E
Sbjct: 387 QQLRREQQLRREQQLRREQQ---LRREQQLRREQQLRREQQLRREQEEERHEQKH--EQE 441
Query: 202 GVGETMTEEQSQ 213
+ + EQ +
Sbjct: 442 RREQRLKREQEE 453
Score = 51.6 bits (122), Expect = 9e-07
Identities = 54/192 (28%), Positives = 91/192 (47%), Gaps = 23/192 (11%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG---VEKPA 109
L+ EE + G R R R Q R R E + +EE +L +E E E+
Sbjct: 1056 LQQEEEQLLGEERETR----RRQELERQYR---KEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 110 ETHLSGKIGAKKLRKL-EEKQARKAQ------REAEEAEREERKRLESQREAEWKKEEER 162
+ ++ ++ + L EE++ R+ Q RE EE ++EE + L + E ++E ER
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
Query: 163 -LRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFL----- 216
R EEE ++EEE+ REEQ +R E + +E ++ + + +E +S L
Sbjct: 1169 QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWE 1228
Query: 217 TEFINYIKQSKV 228
E N ++ +KV
Sbjct: 1229 PEKENAVRDNKV 1240
Score = 50.1 bits (118), Expect = 3e-06
Identities = 40/163 (24%), Positives = 79/163 (48%), Gaps = 6/163 (3%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETH 112
L+ EE R R +R ++ RL+ + + + V E +E E+ L +EE E+ +
Sbjct: 579 LKREEERRQQRLKREQE--ERLEQRLKREEVERLEQEERREQR--LKREEPEEERRQQLL 634
Query: 113 LSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEE 172
S + ++ ++L +Q + ++ + E EER +RE E ++ E+ L EE+++
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694
Query: 173 EERKAR--EEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E K+R + Q Q E E + + + + G+ +EQ +
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/169 (25%), Positives = 75/169 (44%), Gaps = 14/169 (8%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
+ EE G P +RR Q R ++ E + EEE ++ + E+ + E
Sbjct: 968 QKEEQLLGEEPEKRR-------RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 114 SGKIGAKK----LRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQ 169
K ++ L + E ++ R +RE + E EE ++ E Q E ++ R LE +
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 170 KEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
++EEE + EEQ RE E + +E E + E +++ + L E
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQER---ERQCREEEELQQEEEQLLRE 1126
Score = 48.5 bits (114), Expect = 8e-06
Identities = 50/194 (25%), Positives = 90/194 (46%), Gaps = 30/194 (15%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENE--EEAVILAQEEEGVEKPAET 111
E + R R R+ R+ +L+ +R Q+++ E D EE + QE+E E
Sbjct: 1544 ERGQQRRQDRDRKFRE-EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 112 HLSGKIGAKKLRKLEEKQARK-----AQREAEEAEREERKR-----------------LE 149
L + G ++LR+ +++ R+ +RE ++ R+ER R L
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLR 1662
Query: 150 SQREAEWKKEEERLRLEEEQ---KEEEERKAREEQAQ--REHEEYLKLKEAFVVEEEGVG 204
R+ ++++EE+ L+ EEQ ++E +RK REE+ Q R+ E L+E + + +
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722
Query: 205 ETMTEEQSQSFLTE 218
EE+ TE
Sbjct: 1723 RKFREEEQLRQETE 1736
Score = 48.5 bits (114), Expect = 8e-06
Identities = 49/173 (28%), Positives = 83/173 (47%), Gaps = 23/173 (13%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E EE + + R R+ L Q RR +R D + + +EE+ +++ E L
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQL-RRQEREQQLRHDRDRK----FREEEQLLQEGEEQQL 1684
Query: 114 SGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWK-KEEERLRLEEEQK-- 170
+ +K R+ EE+Q R+ +RE + + E++ R ++E E K +EEE+LR E EQ+
Sbjct: 1685 RRQERDRKFRE-EEQQLRRQERERKFLQEEQQLR---RQELERKFREEEQLRQETEQEQL 1740
Query: 171 -----------EEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQS 212
EE+ R REEQ R E K +E + +E + + ++S
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES 1793
Score = 47.8 bits (112), Expect = 1e-05
Identities = 47/155 (30%), Positives = 80/155 (51%), Gaps = 14/155 (9%)
Query: 63 RPRRRRDLGSRLQAQRRAQRVAWAEADEN--EEEAVILAQEEEGVEKPAETHLSGKIGAK 120
R R+ R+ LQ +R Q++ E D EEE + QE E + + + +
Sbjct: 1617 RDRKFREDEQLLQ-EREEQQLHRQERDRKFLEEEPQLRRQEREQ-QLRHDRDRKFREEEQ 1674
Query: 121 KLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEE-EQKEEEERKARE 179
L++ EE+Q R+ +R+ + E E++ R +RE ++ +EE++LR +E E+K EE + R+
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLR-RQERERKFLQEEQQLRRQELERKFREEEQLRQ 1733
Query: 180 EQAQ---REHEEYLKLKEAFVVEEEGVGETMTEEQ 211
E Q R E Y K ++EEE + E+Q
Sbjct: 1734 ETEQEQLRRQERYRK-----ILEEEQLRPEREEQQ 1763
Score = 47.4 bits (111), Expect = 2e-05
Identities = 37/161 (22%), Positives = 79/161 (49%), Gaps = 21/161 (13%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENE-EEAVILAQEEEGVEKPAETHLS 114
EEP R R R + Q+ +++ E ++ +E +EEE V++ E L
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 115 GKIGAKKLRKLEE--KQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQK-- 170
+ ++ ++LE ++ + Q+E E+ REE+++ +RE ++++EEE R + +Q+
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 171 -------------EEEERKAREEQAQ---REHEEYLKLKEA 195
E+E R+ + RE+E++ +L+++
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDS 1256
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/152 (26%), Positives = 73/152 (48%), Gaps = 30/152 (19%)
Query: 70 LGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQ 129
LG + + R +R W + D + E L +EE+ K + + EEKQ
Sbjct: 1271 LGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR-----------KSQEEKQ 1319
Query: 130 ARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQ---KEEEERKAREEQAQREH 186
+ +RE E+R+R E+ R+ +++EE+ L+ EEQ ++E +RK REE+ + +
Sbjct: 1320 LLREERE------EKRRRQETDRK--FREEEQLLQEREEQPLRRQERDRKFREEELRHQE 1371
Query: 187 EEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
+ F+ EE+ +E+ + FL E
Sbjct: 1372 Q-----GRKFLEEEQ---RLRRQERERKFLKE 1395
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/182 (23%), Positives = 86/182 (47%), Gaps = 23/182 (12%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE + R +R+R Q RR +R D + + +EE+ ++ E LS
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK----FREEEQLRQEREEQQLSR 1574
Query: 116 KIGAKKLRKLEEK-----QARKAQREAEEAEREE-RKRLESQREAEWKKEEERLRLEEEQ 169
+ +K R E+K Q RK + ++ R+E +++L +R+ +++++E+ L+ EEQ
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 170 K------------EEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETM-TEEQSQSFL 216
+ EE + + +E + Q H+ K +E + +EG + + +E+ + F
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 217 TE 218
E
Sbjct: 1695 EE 1696
Score = 46.2 bits (108), Expect = 4e-05
Identities = 51/181 (28%), Positives = 88/181 (48%), Gaps = 35/181 (19%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLR- 123
RRRR+ + Q + RA R + +E + Q EE E+ + LS + ++ R
Sbjct: 739 RRRRESELQWQEEERAHRQQ--QEEEQRRDFTWQWQAEEKSERGRQ-RLSARPPLREQRE 795
Query: 124 ---KLEEKQARKAQREAEEAEREERKRLESQREAEWK--KEEERLR-------LEEE--- 168
+ EE+Q R+ + EE E+E+R+R +RE E + +EEE+L+ L+EE
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
Query: 169 -QKEEEERKARE-------------EQAQREHEEYLK--LKEAFVVEEEGVGETMTEEQS 212
Q+++E R+++E E+ +R H Y K L+E E++ + E E Q
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 213 Q 213
+
Sbjct: 916 E 916
Score = 45.8 bits (107), Expect = 5e-05
Identities = 42/170 (24%), Positives = 73/170 (42%), Gaps = 21/170 (12%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQ------RVAW---AEADENEEEAVILAQEEE 103
LE R RR ++L Q Q R + + W +EAD + + +++E
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Query: 104 GVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEA----------EREERKRLESQRE 153
G + E + +L+ EE++A + Q+E E+ E+ ER R
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Query: 154 AEWKKEEERLRLEEEQKEEEER--KAREEQAQREHEEYLKLKEAFVVEEE 201
+++ ER EE+++ E+R EE+ QR + + KE +EEE
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
Score = 45.4 bits (106), Expect = 6e-05
Identities = 57/198 (28%), Positives = 88/198 (44%), Gaps = 30/198 (15%)
Query: 33 QEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSR-------LQAQRRAQRVAW 85
+E L EE A R + E + R +RRR R L +R Q +
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 86 AEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAE---- 141
E D E + QE+ E L + +K K EE+Q R +RE + +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK-EEQQLRCQEREQQLRQDRDR 1414
Query: 142 --REERKRLESQ-REAEWKKEEERLR--------LEEEQ--KEEEERKAREEQ--AQREH 186
REE ++L Q R+ ++++EE+++R LEEEQ ++E RK REE+ Q
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 187 EEYLKLKE---AFVVEEE 201
E+ L +E F+ EE+
Sbjct: 1475 EQQLHRQERDRKFLEEEQ 1492
Score = 44.7 bits (104), Expect = 1e-04
Identities = 46/183 (25%), Positives = 92/183 (50%), Gaps = 21/183 (11%)
Query: 56 EEPRAGGRPRRRRDLGS--RLQAQRRAQRVAW-AEADENEEEAVILAQEEEGVEKPAETH 112
EE R + R R+ L +L+ Q R Q++ + EEE + QE + + E
Sbjct: 1379 EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 113 LSGKIGAKKLRKLEEKQARKAQ----REAEEA--EREERKRLESQREAEWKKEEERLRLE 166
+ + +K + EE+Q R+ + RE E+ EREE++ +R+ ++ +EE++LR +
Sbjct: 1439 VRRQERERKFLE-EEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 167 EEQKEEEERKAREEQAQR---EHEEYL---KLKEAFVVEEEGV-----GETMTEEQSQSF 215
E ++ E++ R ++ +R E E+ L + + F+ EE+ + G+ +++ + F
Sbjct: 1498 ERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF 1557
Query: 216 LTE 218
E
Sbjct: 1558 REE 1560
Score = 43.9 bits (102), Expect = 2e-04
Identities = 41/172 (23%), Positives = 80/172 (46%), Gaps = 15/172 (8%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E ++ R R R+ R+ R Q R + + + L QEE+ + +
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL-QEEQQLRRQERGQQ 1548
Query: 114 SGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQR------EAEWKKEEERLRLEE 167
+ +K R+ E+ + + +++ ER+ + RLE Q+ E ++ ++E++LR +E
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Query: 168 EQ---KEEEERKAREEQ--AQREHEEYLKLKE---AFVVEEEGVGETMTEEQ 211
Q ++E +RK RE++ Q E+ L +E F+ EE + E+Q
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660
Score = 43.5 bits (101), Expect = 2e-04
Identities = 59/249 (23%), Positives = 100/249 (40%), Gaps = 56/249 (22%)
Query: 54 EPEEPR------AGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEK 107
EPEE R + + RR+ R Q +RR QR+ E +E E+ + EEE E+
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 108 P--------AETHLSGKI--------------------------GAKKLRKLEEKQARKA 133
A + +I G ++ ++ EEK+ R+
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Query: 134 Q----REAEEA-----EREERKRLESQREAEWKKEEERLRLEEEQ--KEEEERKAREEQA 182
+E E A E E+R+ Q +AE K E R RL +E+ ER+ R E+
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 183 QREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRT 242
Q+ + +L +E +E+ + E+ FL E ++ + L++ + GL+
Sbjct: 804 QQREQRFLPEEEE---KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE--EEDGLQE 858
Query: 243 QDTINRIQD 251
R Q+
Sbjct: 859 DQERRRSQE 867
Score = 43.1 bits (100), Expect = 3e-04
Identities = 48/174 (27%), Positives = 82/174 (47%), Gaps = 19/174 (10%)
Query: 56 EEP-RAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLS 114
E+P R R R+ R+ R Q Q R E E L +E++ + E L
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 115 GKIGAKKLRKLEEKQARKAQ----REAEEAER---------EERKRLESQREAEWKKEEE 161
+ +K R+ E++ +R+ + RE E+ R EE ++L +R ++++EE+
Sbjct: 1410 -QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Query: 162 RLRLEEEQ---KEEEERKAREEQAQ-REHEEYLKLKEAFVVEEEGVGETMTEEQ 211
L+ EEQ ++E +RK EE+ Q R E K +E + +E + + EEQ
Sbjct: 1469 LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522
Score = 42.4 bits (98), Expect = 5e-04
Identities = 33/149 (22%), Positives = 73/149 (48%), Gaps = 20/149 (13%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEAD----------ENEEEAVILAQEEE 103
E ++ R R R+ R+ +L+ +R Q++ E+D + EE + Q+ +
Sbjct: 1760 EEQQLRRQERDRKFRE-EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Query: 104 GVEKPAETHLSGKIGAKKLRKLEEKQAR---------KAQREAEEAEREERKRLESQREA 154
G + E L + ++LR+ ++Q R K++RE +E +EE ++ +RE
Sbjct: 1819 GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERER 1878
Query: 155 EWKKEEERLRLEEEQKEEEERKAREEQAQ 183
+ ++E R + +EEQ+ + + + ++ +
Sbjct: 1879 KLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Score = 40.4 bits (93), Expect = 0.002
Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Query: 104 GVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERL 163
G+++ GK + R+ EE Q R R+ + E ++R + ++E +E L
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQE-----QEREL 148
Query: 164 RLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
EEQ E++ER + ++ QR EE + ++ + EE E EEQ QS
Sbjct: 149 AEGEEQSEKQERLEQRDR-QRRDEELWRQRQEWQEREERRAE---EEQLQS 195
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 66.2 bits (160), Expect = 3e-11
Identities = 50/174 (28%), Positives = 90/174 (51%), Gaps = 20/174 (11%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQ-----EEEGVEK 107
L E+ + ++ ++ +R + + A+R+ W + +E E L Q E+E + K
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 677
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQR---EAEEAEREERKRLESQR---EAEWKKEEE 161
AE AK+L + E++ R+ +R E E ER E++R E +R E E ++E+E
Sbjct: 678 AAE--------AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 729
Query: 162 RLRLEEE-QKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
RL+ E E Q+ E+ + ++EQ QRE EE K +E + E + E ++ ++
Sbjct: 730 RLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 783
Score = 55.5 bits (132), Expect = 6e-08
Identities = 48/174 (27%), Positives = 85/174 (48%), Gaps = 27/174 (15%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL-- 122
+R L LQA+ R +++ + + E++ AQ +E EK E L+ + KK
Sbjct: 573 KREERLRKVLQARERVEQMKEEKKKQIEQK---FAQIDEKTEKAKEERLAEEKAKKKAAA 629
Query: 123 RKLEEKQARKAQREA---------EEAEREERKRLESQREAEWKK------------EEE 161
+K+EE +AR+ Q E EE ER ++ L+ ++E E ++ + E
Sbjct: 630 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 689
Query: 162 RLRLEEEQKEEEERKA-REEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
+ R E+E++E+E R+ R EQ +RE E L +E +E E +E+ ++
Sbjct: 690 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 743
Score = 42.7 bits (99), Expect = 4e-04
Identities = 34/112 (30%), Positives = 62/112 (55%), Gaps = 7/112 (6%)
Query: 106 EKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKR--LESQREAEWKKEEERL 163
E+ +L K A++LR+ + ++ ++ + E + +REER R L+++ E KEE++
Sbjct: 538 ERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKK 597
Query: 164 RLEEE--QKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
++E++ Q +E+ KA+EE R EE K K A EE EE+++
Sbjct: 598 QIEQKFAQIDEKTEKAKEE---RLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646
Score = 36.6 bits (83), Expect = 0.030
Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 18/97 (18%)
Query: 126 EEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEER-------KAR 178
+E+Q + R EEAE+ R+++E E++R RLEE + + EER + R
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVE---------EDKRRRLEEVKLKREERLRKVLQARER 587
Query: 179 EEQAQREHEEYLKLKEAFVVE--EEGVGETMTEEQSQ 213
EQ + E ++ ++ K A + E E+ E + EE+++
Sbjct: 588 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 624
Score = 35.0 bits (79), Expect = 0.086
Identities = 51/224 (22%), Positives = 94/224 (41%), Gaps = 25/224 (11%)
Query: 35 PLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDL-GSRL--QAQRRAQRVAWAEADEN 91
P ++ E+A + +P PE P AG + + G R Q+ RR + A ++ +
Sbjct: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
Query: 92 EEEAVILAQEEEGVEKPAETHLSGKIGAKK--------LRKLEEKQARKAQREAEEAERE 143
EE+ + E+E ++ P S A K L ++ Q A + +
Sbjct: 462 EEQHL----EDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMK 517
Query: 144 ERKRLESQREAEWK---KEEERLRLEEEQKEEE-----ERKAREEQAQREHEEYLKLKEA 195
+ + + K E+ER RLE +++EE +K E++ +R E LK +E
Sbjct: 518 SFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREER 577
Query: 196 F--VVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQ 237
V++ E M EE+ + +F ++++ E LA +
Sbjct: 578 LRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE 621
Score = 32.7 bits (73), Expect = 0.43
Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 10/117 (8%)
Query: 42 AGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILA-- 99
A A R+A+ E E + RR ++ R + +RR Q AE + E+ + A
Sbjct: 679 AEAKRLAEQREQERREQERREQERREQE---RREQERREQERQLAEQERRREQERLQAER 735
Query: 100 --QEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREA 154
QE E + + L ++ KK + E+Q R A+R+ +E + ++ K +A
Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQEEQEKKAKEAAGASKA 789
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 66.2 bits (160), Expect = 3e-11
Identities = 50/174 (28%), Positives = 90/174 (51%), Gaps = 20/174 (11%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQ-----EEEGVEK 107
L E+ + ++ ++ +R + + A+R+ W + +E E L Q E+E + K
Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRK 673
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQR---EAEEAEREERKRLESQR---EAEWKKEEE 161
AE AK+L + E++ R+ +R E E ER E++R E +R E E ++E+E
Sbjct: 674 AAE--------AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 725
Query: 162 RLRLEEE-QKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
RL+ E E Q+ E+ + ++EQ QRE EE K +E + E + E ++ ++
Sbjct: 726 RLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEA 779
Score = 55.5 bits (132), Expect = 6e-08
Identities = 48/174 (27%), Positives = 85/174 (48%), Gaps = 27/174 (15%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL-- 122
+R L LQA+ R +++ + + E++ AQ +E EK E L+ + KK
Sbjct: 569 KREERLRKVLQARERVEQMKEEKKKQIEQK---FAQIDEKTEKAKEERLAEEKAKKKAAA 625
Query: 123 RKLEEKQARKAQREA---------EEAEREERKRLESQREAEWKK------------EEE 161
+K+EE +AR+ Q E EE ER ++ L+ ++E E ++ + E
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685
Query: 162 RLRLEEEQKEEEERKA-REEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
+ R E+E++E+E R+ R EQ +RE E L +E +E E +E+ ++
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKA 739
Score = 43.1 bits (100), Expect = 3e-04
Identities = 35/120 (29%), Positives = 65/120 (54%), Gaps = 7/120 (5%)
Query: 98 LAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKR--LESQREAE 155
L + + E+ +L K A++LR+ + ++ ++ + E + +REER R L+++ E
Sbjct: 526 LRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVE 585
Query: 156 WKKEEERLRLEEE--QKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
KEE++ ++E++ Q +E+ KA+EE R EE K K A EE EE+++
Sbjct: 586 QMKEEKKKQIEQKFAQIDEKTEKAKEE---RLAEEKAKKKAAAKKMEEVEARRKQEEEAR 642
Score = 38.9 bits (89), Expect = 0.006
Identities = 50/219 (22%), Positives = 91/219 (41%), Gaps = 40/219 (18%)
Query: 35 PLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDL-GSRLQAQRRAQRVAWAEADENEE 93
P ++ E+A + +P PE P AG + + G R Q ++ ++ +A +
Sbjct: 402 PHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELD 461
Query: 94 EAVILAQEE---------------EGVEKPAETHL----------SGKIGAKKLRKLEEK 128
E L EE V +P T L + + + K K
Sbjct: 462 EEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIK 521
Query: 129 QARKAQREAEEAEREERKRLESQREAEWKK-----EEERLRLEEEQKEEEER-------K 176
+ + + +E ER+ + L + EAE + E++R RLEE + + EER +
Sbjct: 522 RNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQAR 581
Query: 177 AREEQAQREHEEYLKLKEAFVVE--EEGVGETMTEEQSQ 213
R EQ + E ++ ++ K A + E E+ E + EE+++
Sbjct: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
Score = 32.7 bits (73), Expect = 0.43
Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 10/117 (8%)
Query: 42 AGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILA-- 99
A A R+A+ E E + RR ++ R + +RR Q AE + E+ + A
Sbjct: 675 AEAKRLAEQREQERREQERREQERREQE---RREQERREQERQLAEQERRREQERLQAER 731
Query: 100 --QEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREA 154
QE E + + L ++ KK + E+Q R A+R+ +E + ++ K +A
Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQEEQEKKAKEAAGASKA 785
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 65.9 bits (159), Expect = 5e-11
Identities = 71/240 (29%), Positives = 117/240 (48%), Gaps = 40/240 (16%)
Query: 50 PG-PLEPEEPRAGGR--PRRR--RDLGSRLQAQRRAQRVAWAEADENEEEAVI--LAQEE 102
PG P++ P G+ P+R+ ++ ++ + AQ+ A + +E E+ V+ A E+
Sbjct: 313 PGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEK 372
Query: 103 EGVEKPAETHLSGKIG-----------AKKLRKLEEKQAR--KAQREAEEAEREERKRLE 149
+ S +G A K+ + +QAR K Q E E E+EE+ RLE
Sbjct: 373 HAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLE 432
Query: 150 SQREAEWKKEEERLRLEEE-QKEEEERKARE---------------EQAQREHEEYLKLK 193
+ E + K EEERLRLEEE +K+EEERK +E E+A+R+ EE L LK
Sbjct: 433 RE-ELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLK 491
Query: 194 EAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLL 253
E E+E + M E+Q ++ T+ +Q ++ E + Q+ + RI +++
Sbjct: 492 EK--QEQEKQEKAMIEKQKEAAETKAREVAEQMRLE-REQIMLQIEQERLERKKRIDEIM 548
Score = 46.2 bits (108), Expect = 4e-05
Identities = 40/141 (28%), Positives = 71/141 (50%), Gaps = 23/141 (16%)
Query: 45 GRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG 104
G++A+PG + +P R + + L++ R QR+A +E E+ + A+E++
Sbjct: 25 GKIAEPGAVRTSQPNY-----RPQGMEGFLKSDER-QRLAKERREEREK--CLAAREQQI 76
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLR 164
+EK K+ R EKQ + R+ EE +R+R + +R A +K +++LR
Sbjct: 77 LEKQ-----------KRARLQYEKQMEERWRKLEE----QRQREDQKRAAVEEKRKQKLR 121
Query: 165 LEEEQKEEEERKAREEQAQRE 185
EEE+ E R++ E Q E
Sbjct: 122 EEEERLEAMMRRSLERTQQLE 142
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/68 (36%), Positives = 40/68 (58%), Gaps = 4/68 (5%)
Query: 126 EEKQARKAQREAEEAEREERKRL--ESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ 183
EE++ A RE + E+++R RL E Q E W+K EE+ + E++++ E K +Q
Sbjct: 63 EEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEK--RKQKL 120
Query: 184 REHEEYLK 191
RE EE L+
Sbjct: 121 REEEERLE 128
Score = 40.4 bits (93), Expect = 0.002
Identities = 23/61 (37%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
Query: 134 QREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLK 193
QR A+E REER++ + RE + ++++R RL+ E++ EE + EEQ QRE ++ ++
Sbjct: 55 QRLAKE-RREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVE 113
Query: 194 E 194
E
Sbjct: 114 E 114
Score = 32.3 bits (72), Expect = 0.56
Identities = 41/169 (24%), Positives = 74/169 (43%), Gaps = 10/169 (5%)
Query: 33 QEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENE 92
QE + EE R E E R R++ + R + +++ Q E +
Sbjct: 420 QERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQE--GEEKRKAG 477
Query: 93 EEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQR 152
EEA A+EE +++ E K +K ++ E +A RE E R ER+++ Q
Sbjct: 478 EEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKA----REVAEQMRLEREQIMLQI 533
Query: 153 EAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
E E + E + R++E K RK+ ++ + + ++ A VE++
Sbjct: 534 EQE--RLERKKRIDEIMK--RTRKSDVPPQVKKEDPKVGVQPAVCVEKK 578
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 64.3 bits (155), Expect = 1e-10
Identities = 49/165 (29%), Positives = 81/165 (49%), Gaps = 5/165 (3%)
Query: 33 QEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQR-RAQRVAWAEADEN 91
QE + E+ G + + EE + RR++ R Q ++ R Q E +E
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461
Query: 92 EEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEK--QARKAQREAEEAEREERKRLE 149
+E E+EG K E + +K+R+ EEK + K RE EE RE+ + ++
Sbjct: 462 MQEQEEKMGEQEG--KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519
Query: 150 SQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
Q E W++EE+ EE+ +E+EE+ R+E+ RE E L+ +E
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564
Score = 61.2 bits (147), Expect = 1e-09
Identities = 41/156 (26%), Positives = 83/156 (53%), Gaps = 20/156 (12%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAET-HLSGKIGAK--------KLRKL 125
+ RR + + W + ++ + ++ ++EE + + E H KI + K+R+
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 375
Query: 126 EEKQARKAQ--------REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKA 177
E++Q ++A+ RE EE RE+ + ++ Q E ++EE+ EEE +E+EE+
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Query: 178 REEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
R+E+ RE E+ ++ +E + E+E E M E++ +
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQE---EMMQEQEEK 468
Score = 61.2 bits (147), Expect = 1e-09
Identities = 52/181 (28%), Positives = 94/181 (51%), Gaps = 24/181 (13%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQ--RRAQRVAWAEADENEEEAVILAQEE---EGVEKP 108
E EE R R ++ +A+ R+ +++ E E+E ++ QEE E EK
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 109 AETHLSGKIGAKKLRKLEEK--QARKAQREAEEAEREERKRLESQ-------------RE 153
E + +K+R+ EEK + K RE EE RE+ + ++ Q +E
Sbjct: 421 WEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 154 AEWKKEEERLRLEEEQKEEEERKAREEQAQ-REHEEYLKLKEAFVVEEEGVGETMTEEQS 212
A+ +++EE++R +EE+ E+E+K RE++ + RE EE ++ +E + E+E E M E++
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE---EKMCEQEE 537
Query: 213 Q 213
+
Sbjct: 538 K 538
Score = 56.6 bits (135), Expect = 3e-08
Identities = 41/146 (28%), Positives = 74/146 (50%), Gaps = 17/146 (11%)
Query: 68 RDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEE 127
R+L ++ Q + + + ++ +EE I Q EK E +K+R+ EE
Sbjct: 347 RELEEKMHEQEKIRE----QEEKRQEEEKIREQ-----EKRQEQEAKMWRQEEKIREQEE 397
Query: 128 KQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHE 187
K RE EE +E+ +++ Q E W++EEE EE+ + +EE+ +E+ RE E
Sbjct: 398 K-----IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQE 452
Query: 188 EYLKLKEAFVVEEEGVGETMTEEQSQ 213
E ++ +E + E+E E M E++ +
Sbjct: 453 EKIREQEEMMQEQE---EKMGEQEGK 475
Score = 55.5 bits (132), Expect = 6e-08
Identities = 41/159 (25%), Positives = 78/159 (49%), Gaps = 10/159 (6%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQ-----RRAQRVAWAEADENEEEAVILAQEE---EG 104
++ +E + G + + + +Q Q R+ +++ E E+E I QEE E
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQARKAQ--REAEEAEREERKRLESQREAEWKKEEER 162
EK E K+++ EEK R+ + RE E+ RE+ +++ Q E ++EE+
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 525
Query: 163 LRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
EE+ E+EE+ +E+ R EE ++ +E + ++E
Sbjct: 526 WEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564
Score = 53.5 bits (127), Expect = 2e-07
Identities = 38/139 (27%), Positives = 72/139 (51%), Gaps = 5/139 (3%)
Query: 77 QRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQRE 136
Q R +++ E E+E + QEE EK + ++ +K K+ E + + ++E
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357
Query: 137 AEEAEREERKRLESQREAEWKKEEE--RLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
+ E+R+ E RE E ++E+E R EE+ +E+EE+ +E+ +E EE + +E
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE 417
Query: 195 AFVVEEEGVGETMTEEQSQ 213
+ E+E E M E++ +
Sbjct: 418 EKMWEQE---EEMQEQEEK 433
Score = 52.8 bits (125), Expect = 4e-07
Identities = 42/153 (27%), Positives = 78/153 (50%), Gaps = 8/153 (5%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADE--NEEEAVILAQEEEGVEKPAETHLSGKIGAKKL 122
+R+ + L Q++ Q AEAD E ++V + + E L+ + K
Sbjct: 236 KRKLERAKLLLPQQQLQ----AEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291
Query: 123 RKLEEKQARKAQ-REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQ 181
R+ E+ Q R+ + +E EE RE+ +++ Q E W+KEE ++R +EE E+E K RE +
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEE-KMRRQEEMMWEKEEKIRELE 350
Query: 182 AQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
+ +E ++ +E EEE + E ++ ++
Sbjct: 351 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 383
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/194 (25%), Positives = 91/194 (46%), Gaps = 43/194 (22%)
Query: 52 PLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQE--EEGVEKPA 109
P + + A + + + ++LQAQ + W ++ +EE + +E +E EK
Sbjct: 247 PQQQLQAEADHLGKELQSVSAKLQAQVEENEL-WNRLNQQQEEKMWRQEEKIQEREEKIQ 305
Query: 110 ETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEE--------- 160
E +K+R+ EEK R+ EE E+ +++ Q E W+KEE
Sbjct: 306 EQE-------EKIREQEEKMRRQ-----EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 161 ---ERLRLEEEQKEEEER----KAREEQAQ---------REHEEYLKLKEAFVVEEEGVG 204
E++R +EE+++EEE+ + R+EQ RE EE ++ +E + E+E
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQE--- 410
Query: 205 ETMTEEQSQSFLTE 218
E M E++ + + E
Sbjct: 411 EKMGEQEEKMWEQE 424
Score = 36.6 bits (83), Expect = 0.030
Identities = 42/177 (23%), Positives = 86/177 (48%), Gaps = 16/177 (9%)
Query: 89 DENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL-RKLEEKQARKAQREAEEAEREERKR 147
DE +E QE+ + + ++ + ++ K+L RKLE + Q++ + K
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 261
Query: 148 LES-----QREAEWKKEEERLRLEEEQK---EEEERKAREEQAQREHEEYLKLKEAFVVE 199
L+S Q + E + RL ++E+K +EE+ + REE+ Q + E+ + +E +
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 200 EEGVGETMTEEQSQSFLTEFINYIKQSKVVLLED-LASQVGLRTQDTINRIQDLLAE 255
E E M E++ + E + + K+ K+ LE+ + Q +R Q+ + ++ + E
Sbjct: 322 E----EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 63.9 bits (154), Expect = 2e-10
Identities = 38/143 (26%), Positives = 77/143 (53%), Gaps = 4/143 (2%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
+ R +R+ E EEE ++ QEE+ E+ + + ++ K++E++ + +
Sbjct: 554 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
+E + E+EE +++ Q E W++EE+ EE+ E+EE+ +E+ RE EE ++ +E
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Query: 195 AFVVEEE----GVGETMTEEQSQ 213
+ E+E G E M E++ +
Sbjct: 674 EKMREQEEKMQGQEEKMREQEEK 696
Score = 60.8 bits (146), Expect = 1e-09
Identities = 50/191 (26%), Positives = 97/191 (50%), Gaps = 15/191 (7%)
Query: 62 GRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKK 121
G+ R + + R + + R Q E ++ E L ++EE +++ E + +K
Sbjct: 269 GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE---EK 325
Query: 122 LRKLEEKQARKAQR--EAEEAEREERKRLESQREAEWKKEE------ERLRLEEEQKEEE 173
+R+ EEK R+ +R E E+ RE+ +++ Q E W+++E ER+R E+E+ E+
Sbjct: 326 MREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR-EQEKMWEQ 384
Query: 174 ERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLED 233
E K +EE+ RE E+ ++ +E + E+E E M +++ + E + +Q E
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQE---EKMQKQEENMWEQEEKEWQQQRLPEQKEK 441
Query: 234 LASQVGLRTQD 244
L Q ++ Q+
Sbjct: 442 LWEQEKMQEQE 452
Score = 55.8 bits (133), Expect = 5e-08
Identities = 40/157 (25%), Positives = 77/157 (49%), Gaps = 7/157 (4%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKI--GAKKLRKLEEKQARKAQR 135
R+ +R+ E E+E + QE+ E+ E K KKLR+ EE+ +
Sbjct: 259 RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM-----Q 313
Query: 136 EAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEA 195
E EE E+ +++ Q E W++EE E++ +E+E++ +E+ E +E L+ KE
Sbjct: 314 EQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEE 373
Query: 196 FVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLE 232
+ E+E + E + Q + + E +++ + + E
Sbjct: 374 RMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410
Score = 55.5 bits (132), Expect = 6e-08
Identities = 34/99 (34%), Positives = 61/99 (61%), Gaps = 9/99 (9%)
Query: 120 KKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE 179
KK+RK EEK R+ EE RE+ ++ Q E + +++E+RLR +E++ E+E++ RE
Sbjct: 248 KKIRKQEEKMWRQ-----EERLREQEGKMREQEE-KMRRQEKRLREQEKELREQEKELRE 301
Query: 180 EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
++ RE EE ++ +E + E+E E M E++ + + E
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQE---EKMREQEEKMWRQE 337
Score = 55.5 bits (132), Expect = 6e-08
Identities = 39/160 (24%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
+E R + R R+ R++ Q++ W + ++ EE QE++ ++ +
Sbjct: 505 QEERMWEQDERLREKEERMREQKKM----WQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 116 KIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEER 175
++ ++ + EE++ RE EE +E+ +++ Q E W++EE+ EE+ E+EE+
Sbjct: 561 RMREREKKMREEEEMM---REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 176 --KAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
+ EE +E EE + +E + E+E E M E++ +
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQE---EKMWEQEEK 654
Score = 53.5 bits (127), Expect = 2e-07
Identities = 34/141 (24%), Positives = 70/141 (49%), Gaps = 14/141 (9%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R + R + W + ++ ++ + +EE + + E +LR+ EE+ +
Sbjct: 477 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDE----------RLREKEERMREQ 526
Query: 133 AQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKL 192
+ +E + E K+ + Q + W +EE++R EE +E E++ EE+ RE EE ++
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTW-DQEEKMREEERMREREKKMREEEEMMREQEEKMQE 585
Query: 193 KEAFVVEEEGVGETMTEEQSQ 213
+E + E+E E M E++ +
Sbjct: 586 QEEKMREQE---EKMWEQEEK 603
Score = 52.8 bits (125), Expect = 4e-07
Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 12/128 (9%)
Query: 93 EEAVILAQEEEGVEKPAETHLSGKIGAKKLRK----LEEKQARKAQREA---EEAEREER 145
+E + LA+ E+ +E L+ K +KL + L + Q Q E EE RE+
Sbjct: 193 QEKLRLAESEK-----SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 247
Query: 146 KRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGE 205
K++ Q E W++EE E + +E+EE+ R+E+ RE E+ L+ +E + E++ + E
Sbjct: 248 KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLRE 307
Query: 206 TMTEEQSQ 213
+ Q Q
Sbjct: 308 QEEQMQEQ 315
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/158 (24%), Positives = 81/158 (51%), Gaps = 12/158 (7%)
Query: 64 PRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEE--GVEKPAETHLSGKIGAKK 121
P ++ L + + Q + +++ W + ++ ++ + QE++ EK E +K
Sbjct: 436 PEQKEKLWEQEKMQEQEEKI-WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 494
Query: 122 LRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEE------ER 175
+R E+K + +R E+ ER K + + + ++EE++R E++ +E+E E
Sbjct: 495 MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE 554
Query: 176 KAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
K REE+ RE E+ ++ +E + E+E E M E++ +
Sbjct: 555 KMREEERMREREKKMREEEEMMREQE---EKMQEQEEK 589
Score = 48.1 bits (113), Expect = 1e-05
Identities = 36/130 (27%), Positives = 70/130 (53%), Gaps = 7/130 (5%)
Query: 92 EEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQ 151
++E + Q+E EK K+ ++ + EEK+ ++ +++ + E + R+ E
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE-ERM 562
Query: 152 REAEWK-KEEERLRLEEEQK--EEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMT 208
RE E K +EEE + E+E+K E+EE+ +E+ E EE ++ +E + E+E E M
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE---EKMW 619
Query: 209 EEQSQSFLTE 218
E++ + + E
Sbjct: 620 EQEEEDKMQE 629
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/156 (27%), Positives = 80/156 (51%), Gaps = 12/156 (7%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQAR- 131
RL Q + R + + EE + Q+E EK K+ ++ + EE++ R
Sbjct: 339 RLWEQEKQMREQEQKMRDQEER--MWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Query: 132 --KAQREAEEAEREERKRLESQREAEWKKEE---ERLRL-EEEQKEEEERKAREEQAQ-R 184
K RE EE RE+ ++++ Q E W++EE ++ RL E+++K E+ K +E++ +
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 185 EHEEYLKLKEAFVVEEEGV--GETMTEEQSQSFLTE 218
E EE ++ +E +E+ + E M E++ Q + E
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 492
Score = 46.6 bits (109), Expect = 3e-05
Identities = 32/117 (27%), Positives = 62/117 (52%), Gaps = 9/117 (7%)
Query: 81 QRVAWAEADENEEEAVILAQEEEGV----EKPAETHLSGKIGAKKLRKLEEKQARKAQ-- 134
+ + W + ++ +E+ + ++EE + EK E + +K+R+ EEK + +
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQR---EHEE 188
RE EE R + +++ Q E W +EE+ EE +++EE + ++E+ Q EHEE
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 46.2 bits (108), Expect = 4e-05
Identities = 34/128 (26%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREA 137
R+ +R+ E E+E + QEE E+ + L K +++R+ E+ ++ + +
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQ--DERLREK--EERMREQEKMWEQEEKMQE 390
Query: 138 EEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFV 197
EE RE K++ + E +++EE+++ +EE E+E K ++Q E +E L +E
Sbjct: 391 EERIREREKKMREEEET-MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 198 VEEEGVGE 205
+EE + E
Sbjct: 450 EQEEKIWE 457
Score = 45.8 bits (107), Expect = 5e-05
Identities = 37/152 (24%), Positives = 72/152 (47%), Gaps = 19/152 (12%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQ-----------RRAQRVAWAEADE-NEEEAVILAQEEE 103
EE R R ++ R+ ++ Q R + W + ++ E+E + QEE+
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 104 GVEKPAETHLSGKIGA-----KKLRKLEEK--QARKAQREAEEAEREERKRLESQREAEW 156
E+ E + + +K+++ EEK + + RE EE RE+ ++++ Q E
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMR 677
Query: 157 KKEEERLRLEEEQKEEEERKAREEQAQREHEE 188
++EE+ EE+ +E+EE+ +E+ EE
Sbjct: 678 EQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE 709
Score = 44.7 bits (104), Expect = 1e-04
Identities = 30/129 (23%), Positives = 68/129 (52%), Gaps = 5/129 (3%)
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREA--EEAEREE 144
E D+ +E+ ++ ++EE +++ E + +K+R+ EEK + ++ EE RE+
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQE---EKMREQEEKMREQEEKMQGQEEKMREQ 679
Query: 145 RKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVG 204
++++ Q E ++EE+ EE+ +EE+ +E+ EE + +E ++E +
Sbjct: 680 EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Query: 205 ETMTEEQSQ 213
E + E + +
Sbjct: 740 ERLPEHEER 748
Score = 43.5 bits (101), Expect = 2e-04
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 44/199 (22%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q + +E R + R R+ R++ Q + W + ++ +EE I +E+ K
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKM----WEQEEKMQEEERIREREK----KM 401
Query: 109 AETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERK-------RLESQREAEWKKEE- 160
E + + +K++K EE + ++E ++ E+K +++ Q E W++EE
Sbjct: 402 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 461
Query: 161 -----------------ERLRLEEEQKEEEERKAR--------EEQAQREHEEYLKLKEA 195
E++R +E+Q E+E K R +E+ E +E L+ KE
Sbjct: 462 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE 521
Query: 196 FVVEEEGV---GETMTEEQ 211
+ E++ + E M EE+
Sbjct: 522 RMREQKKMWQQEEKMREEK 540
Score = 42.4 bits (98), Expect = 5e-04
Identities = 40/176 (22%), Positives = 81/176 (46%), Gaps = 19/176 (10%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQ----RRAQRVAWAEADENEEEAVILAQEEEGVEKPAET 111
EE R R ++ R+ ++ Q ++ + W + ++ ++ + Q+E+ E+
Sbjct: 390 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQ 449
Query: 112 HLSGKIGAK--KLRKLEEKQARKAQ-------REAEEAEREERKRLESQREAEWKKEEER 162
KI + K+R EE ++ + RE E+ E+ +++ Q + W +EE
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERM 509
Query: 163 LRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
+E +E+EER RE++ + EE K++E +E+ E T +Q + E
Sbjct: 510 WEQDERLREKEER-MREQKKMWQQEE--KMREEKKTQEQ---EKKTWDQEEKMREE 559
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 63.2 bits (152), Expect = 3e-10
Identities = 39/157 (24%), Positives = 80/157 (50%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
E + R R +++ + + R ++ E + E E +++E E+ +
Sbjct: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGK 131
Query: 116 KIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEER 175
+ K+ RK EE++ R+ ++E E ERE ++R + +R+ +KEEER E +++++ ER
Sbjct: 132 ERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
Query: 176 KAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQS 212
+E + +RE +E + K+ +EE E + Q+
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228
Score = 59.7 bits (143), Expect = 3e-09
Identities = 41/141 (29%), Positives = 72/141 (51%), Gaps = 8/141 (5%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E ++ R R + RR+ R + +R ++ E + E++ +E E ++ E
Sbjct: 50 EGKKERESERKKERRE---REKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN 106
Query: 114 SGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEE 173
+K +K E+K+ + +E +E ER+E ++ E ++E E KKEE E+++E +
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE-----REKERERK 161
Query: 174 ERKAREEQAQREHEEYLKLKE 194
ERK RE + E EE K KE
Sbjct: 162 ERKKRERKQVGEKEEERKEKE 182
Score = 57.8 bits (138), Expect = 1e-08
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 9/140 (6%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKL 125
R R++ +R + ++ + E E E+ + E E+ E K G +K +
Sbjct: 41 REREIETRKEGKKERESERKKERREREKR-----KREREKERKRERGKKEKKGERKKEER 95
Query: 126 EEKQARKAQREAEEAEREERKRLESQREAEWKKE-EERLRLEE---EQKEEEERKAREEQ 181
E K+ R+ + E E+E+RK+ E + KE +ER R EE E+++E ERK E +
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 182 AQREHEEYLKLKEAFVVEEE 201
+RE +E K + V E+E
Sbjct: 156 KERERKERKKRERKQVGEKE 175
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/172 (25%), Positives = 82/172 (47%), Gaps = 16/172 (9%)
Query: 23 RSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQR 82
R RG+ G+ E R + E +E R + + +++ G + + +R
Sbjct: 79 RERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR---KKKEKKERGRTSKEGKERER 135
Query: 83 VAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAER 142
+ +E +E +++E EK E K+ +K E KQ + + E +E ER
Sbjct: 136 KEERKREERKERE----RKKEEREKERER--------KERKKRERKQVGEKEEERKEKER 183
Query: 143 EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
+ERK+ E R+ E KKE ER E +KE ++++ R+++ Q++ + + KE
Sbjct: 184 KERKKRERNRK-ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/92 (32%), Positives = 50/92 (54%), Gaps = 4/92 (4%)
Query: 126 EEKQARKAQREAEEAEREERKR-LESQREAEWKKEE---ERLRLEEEQKEEEERKAREEQ 181
E K+ R+++R+ E ERE+RKR E +R+ E K+E ER + E E+K+ K +E
Sbjct: 50 EGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEG 109
Query: 182 AQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
++E + + KE +EG EE+ +
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKR 141
Score = 45.4 bits (106), Expect = 6e-05
Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 6/149 (4%)
Query: 71 GSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQA 130
G + + + R + + + + E E+ + E ++ E K K K E++
Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
Query: 131 RKAQREAEEAEREERKRLESQ-REAEWKKEEERLRLEEEQKEEEERKAREEQAQR----- 184
+ +R+ E+E ++ E + R+ + KKE R E +++E +E + REE+ +R
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 185 EHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E E+ + KE E + VGE E + +
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEK 181
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 62.8 bits (151), Expect = 4e-10
Identities = 46/169 (27%), Positives = 83/169 (49%), Gaps = 8/169 (4%)
Query: 52 PLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQE--EEGVEKPA 109
P + + A + + + ++LQAQ + W ++ +EE + +E +E EK
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENEL-WNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 110 ETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQ 169
E + +K+R+ EEK R+ EE E+ +++ Q E W+KEE+ R EE
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQ-----EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 372
Query: 170 KEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
E+EE+ R+E+ E EE ++ E + E+E + E + Q + + E
Sbjct: 373 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 421
Score = 58.2 bits (139), Expect = 1e-08
Identities = 37/154 (24%), Positives = 80/154 (51%), Gaps = 16/154 (10%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAET-HLSGKIGAKKLR 123
R+ + + + RR + + W + ++ + ++ ++EE + + E H KI ++ +
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 124 KLEEKQARKAQREAE---------EAEREERKRLESQREAEWKKEE-----ERLRLEEEQ 169
+ EE++ R+ ++ E E RE+ +++ Q + W++EE E++R EEE+
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR-EEEK 471
Query: 170 KEEEERKAREEQAQREHEEYLKLKEAFVVEEEGV 203
++E+E R+E+ E EE + KE +EE +
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505
Score = 57.8 bits (138), Expect = 1e-08
Identities = 38/160 (23%), Positives = 85/160 (53%), Gaps = 16/160 (10%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRK 124
R++ + + + R+ + W + ++ E+ + ++EE + + E KI ++
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE-----KIREQEEMW 547
Query: 125 LEEKQARKAQREAEEAEREERK--------RLESQREAEWKKEEERLRLEEEQKEEEERK 176
EE++ + ++ EE +R+E++ ++ Q E W++EE+ EE+++E+EE+
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Query: 177 AREEQAQREHEEYLKLKEAFVVEEE---GVGETMTEEQSQ 213
++E+ RE EE ++ +E + E+E E MT+EQ +
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
Score = 57.4 bits (137), Expect = 2e-08
Identities = 39/155 (25%), Positives = 82/155 (52%), Gaps = 21/155 (13%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRK 124
R+ + + + RR + + W + ++ + ++ ++EE + + E + +K+R+
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKIRE 395
Query: 125 LEEK-------QARKAQREAEEAEREERKRLESQ-----REAEWKKEEERLRLEE----- 167
LEEK + ++ +R+ EE RE+ KR E + +E + +++EE++R +E
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR 455
Query: 168 -EQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
E+K E+ K REE+ ++E EE + +E +EE
Sbjct: 456 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Score = 57.0 bits (136), Expect = 2e-08
Identities = 44/157 (28%), Positives = 82/157 (52%), Gaps = 15/157 (9%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R + + R Q W E ++ E+ I +E+ ++ +K+R+ EEK R+
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE-----EKIREQEEKVWRQ 589
Query: 133 AQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ-REHEEYLK 191
EE RE+ ++ + Q E WK +EE++R +EE+ +E+E K RE++ + RE EE +
Sbjct: 590 -----EEKIREQEEKRQEQEEKMWK-QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 192 LKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKV 228
+E + E+E E M E++ + E + ++ K+
Sbjct: 644 EQEEKMGEQE---EKMCEQEEKMQEQEETMWRQEEKI 677
Score = 57.0 bits (136), Expect = 2e-08
Identities = 37/141 (26%), Positives = 75/141 (53%), Gaps = 8/141 (5%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEE---EGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
R+ +++ E E+E + QEE E EK E + +K+R+ EE + +
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647
Query: 135 REAEEAER--EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKL 192
+ E+ E+ E+ ++++ Q E W++EE+ E++ +E+EE+ +E+ +E EE +
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
Query: 193 KEAFVVEEEGVGETMTEEQSQ 213
+E + E+E E M E++ +
Sbjct: 708 QEEKMCEQE---EKMQEQEEK 725
Score = 56.6 bits (135), Expect = 3e-08
Identities = 40/146 (27%), Positives = 73/146 (50%), Gaps = 7/146 (4%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEE---EGVEKPAE 110
+ +E + + + R+ ++Q Q +++ E E+E + QEE E EK E
Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQE--EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Query: 111 THLSGKIGAKKLRKLEEK--QARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEE 168
+ + + + EEK + K RE EE RE+ + ++ Q E W++EE+ EE+
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 718
Query: 169 QKEEEERKAREEQAQREHEEYLKLKE 194
+E+EE+ R+E+ E E L+ +E
Sbjct: 719 MQEQEEKMRRQEEKMWEQEVRLRQQE 744
Score = 55.5 bits (132), Expect = 6e-08
Identities = 42/158 (26%), Positives = 84/158 (53%), Gaps = 12/158 (7%)
Query: 65 RRRRDLGSRLQAQRRAQRVA-WAEADE-NEEEAVILAQEEEGVEKPAETHLSGKIGAKKL 122
+R+ + R Q +R+ Q W + ++ E+E I QE++ + + H KI ++
Sbjct: 412 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 471
Query: 123 RKLEEKQARKAQREAEEAE--------REERKRLESQREAEWKKEEERLRLEEEQ-KEEE 173
R+ +E+ R+ ++ E+ E E+ +++ Q E W+ +EE++R +EE+ +E+E
Sbjct: 472 RQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR-QEEKIREQEEKIREQE 530
Query: 174 ERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQ 211
E+ R+E+ RE EE + +E +E+ E +EQ
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQ 568
Score = 55.1 bits (131), Expect = 8e-08
Identities = 42/140 (30%), Positives = 73/140 (52%), Gaps = 9/140 (6%)
Query: 85 WAEADE-NEEEAVILAQEE---EGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ--REAE 138
W + ++ E+E + QEE E EK E +K+R+ EEK + + RE E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQE 632
Query: 139 EAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVV 198
E RE+ + + Q E ++EE+ EE+ +E+EE R+E+ RE E+ ++ +E +
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIR 692
Query: 199 EEEGVGETMTEEQSQSFLTE 218
E+E E M E++ + + E
Sbjct: 693 EQE---EMMQEQEEKMWEQE 709
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/163 (24%), Positives = 79/163 (48%), Gaps = 10/163 (6%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQ-----RRAQRVAWAEADENEEEAVILAQEEE 103
Q + +E + + + R+ + Q Q ++ +++ E E+E I QEE+
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 104 GVEKPAETH-LSGKIGAKKLRKLEEKQARKAQREA----EEAEREERKRLESQREAEWKK 158
E+ T K+G ++ + E+++ + Q E EE RE+ K++ Q E ++
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
Query: 159 EEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
EE EE+ E+EE+ +E+ +E EE ++ +E + E+E
Sbjct: 695 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/142 (30%), Positives = 77/142 (54%), Gaps = 24/142 (16%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R + +R+ Q W + ++ E+ I Q+E+ E+ +K+RK EEK R+
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE-----------EKIRKQEEKVWRQ 515
Query: 133 AQ--REAEEAEREERKRL----ESQREAE--WKKEE---ERLRLEEEQK--EEEERKARE 179
+ RE EE RE+ +++ E RE E W++EE E+ ++ EE+K E+E++ R+
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 180 EQAQREHEEYLKLKEAFVVEEE 201
E+ RE EE + +E + E+E
Sbjct: 576 EEKIREQEEKVWRQEEKIREQE 597
Score = 51.2 bits (121), Expect = 1e-06
Identities = 46/173 (26%), Positives = 86/173 (49%), Gaps = 27/173 (15%)
Query: 69 DLGSRLQAQ------RRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKI---GA 119
+L +RL Q R+ +++ E E+E I QEE+ E+ + ++
Sbjct: 289 ELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
Query: 120 KKLRKLEEKQARKAQ--REAEEAEREERKRLESQREAEWKKEE------------ERLRL 165
+K+R+ EE K + R EE E+ +++ Q E W+KEE E++R
Sbjct: 349 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
Query: 166 EEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
+EE+++EEE K RE++ ++E E + +E + E+E E + E++ + + E
Sbjct: 409 QEEKRQEEE-KIREQEKRQEQEAKMWRQEEKIREQE---EKIREQEKKMWRQE 457
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/148 (25%), Positives = 78/148 (52%), Gaps = 15/148 (10%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
+ RR + + W + ++ + ++ ++EE + + E + +K+R+ EE K +
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKMRRQEEMMWEKEE 391
Query: 135 --REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEE------ERKAREEQAQ-RE 185
RE EE E+ K E + E ++EEE++R +E+++E+E E K RE++ + RE
Sbjct: 392 KIRELEEKMHEQEKIREQE---EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
Query: 186 HEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E+ + +E + E+E + E ++ +
Sbjct: 449 QEKKMWRQEEKIHEQEKIREEEKRQEQE 476
Score = 50.4 bits (119), Expect = 2e-06
Identities = 36/137 (26%), Positives = 74/137 (54%), Gaps = 9/137 (6%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R + + Q W E E+E + QEE+ E+ + +K+R+ EEK+ +
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ----EEKIREQEEKRQEQ 603
Query: 133 AQR--EAEEAEREERKRLESQREAEWKKEEERLRLEEE--QKEEEERKAREEQAQREHEE 188
++ + EE RE+ ++++ Q E + +++EE++R +EE Q++EE+ +EE+ + E+
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEE-KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 662
Query: 189 YLKLKEAFVVEEEGVGE 205
+ +E +EE + E
Sbjct: 663 MQEQEETMWRQEEKIRE 679
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/147 (24%), Positives = 77/147 (52%), Gaps = 17/147 (11%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R Q ++R + E ++ +E+ + ++EE + + E K+R+ E+K R+
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE----------KIREQEKKMWRQ 456
Query: 133 AQREAEEAE-REERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLK 191
++ E+ + REE KR Q + E ++EE++ +EE ++E+ +E+ R+ EE +
Sbjct: 457 EEKIHEQEKIREEEKR---QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVW 513
Query: 192 LKEAFVVEEEGVGETMTEEQSQSFLTE 218
+E + E+E E + E++ + + E
Sbjct: 514 RQEEKIREQE---EKIREQEEKMWRQE 537
Score = 46.2 bits (108), Expect = 4e-05
Identities = 36/144 (25%), Positives = 72/144 (50%), Gaps = 9/144 (6%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q + +E + + + R+ +++ Q + + E EE+ + ++EE +++
Sbjct: 610 QEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK---MCEQEEKMQEQ 666
Query: 109 AET--HLSGKIGA--KKLRKLEEK--QARKAQREAEEAEREERKRLESQREAEWKKEEER 162
ET KI KK+R+ EEK + + +E EE E+ +++ Q E ++EE+
Sbjct: 667 EETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 726
Query: 163 LRLEEEQKEEEERKAREEQAQREH 186
R EE+ E+E R ++E+ +EH
Sbjct: 727 RRQEEKMWEQEVRLRQQEEKMQEH 750
Score = 33.1 bits (74), Expect = 0.33
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 6/147 (4%)
Query: 89 DENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL-RKLEEKQARKAQREAEEAEREERKR 147
DE +E QE+ + + ++ + ++ K+L RKLE + Q++ + K
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
Query: 148 LESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETM 207
L+S + EE +++EE+ R+E+ +E EE ++ +E + E+E E +
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKI 330
Query: 208 TEEQSQSFLTEFINYIKQSKVVLLEDL 234
E++ + E + + K+ K+ E++
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEM 357
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 62.8 bits (151), Expect = 4e-10
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 35/193 (18%)
Query: 48 AQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQ-----RVAWAEADENEEEAVILAQEE 102
A+ LE E A R +R + R + RR Q R E EEE + ++E
Sbjct: 726 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 785
Query: 103 EGVEKPAETHLSGKIGAKKLRKLEEKQARK-AQREAEEAEREERKR------LESQRE-- 153
E + + E +I ++ R+ EE+Q ++ A R EE REE +R L Q E
Sbjct: 786 EALRRQREQ----EIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
Query: 154 AEWKKEEE---------RLRLEEE----QKEEEERKAREEQAQREHEEYLKLKEAFVVEE 200
A+W +EEE RLR+EEE + EEEERK +E + QR+ E + ++ ++
Sbjct: 842 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ----QQ 897
Query: 201 EGVGETMTEEQSQ 213
E + ++Q Q
Sbjct: 898 EALRRLQQQQQQQ 910
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/188 (28%), Positives = 95/188 (50%), Gaps = 28/188 (14%)
Query: 50 PGPL-----EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG 104
PGP + E+ +A + RR+ + ++A+R + E ++E ++ Q+EE
Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERRE--AEMRAKREEEERKRQEELRRQQEEILRRQQEEE 770
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQ-ARKAQREAEEAEREER--KRLESQR--EAEWKKE 159
++ E L+ + + LR+ E++ A + QRE EE +++E +RLE +R E E +K+
Sbjct: 771 RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 830
Query: 160 EERLRLEEE------------QKEEEERKAR--EEQAQREHEEYLKLKEAFVVEEEGVGE 205
EE LR +EE Q+ EE + R EE A+ HEE + ++ V+ + E
Sbjct: 831 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ--KE 888
Query: 206 TMTEEQSQ 213
M + Q Q
Sbjct: 889 LMRQRQQQ 896
Score = 54.7 bits (130), Expect = 1e-07
Identities = 53/243 (21%), Positives = 117/243 (48%), Gaps = 26/243 (10%)
Query: 71 GSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQA 130
G L+ ++ ++ A+ ++ EA + A+ EE K E + +++ + ++++
Sbjct: 714 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ---EEILRRQQEEE 770
Query: 131 RKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE-EQAQREHEEY 189
RK + E E A R++ + L QRE E +R EEE+++++E R E+ +RE EE
Sbjct: 771 RKRREEEELARRKQEEALRRQREQEIALRRQR---EEEERQQQEEALRRLEERRREEEER 827
Query: 190 LKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRI 249
K +E +EE + EE+ E ++++++ + E+ A LR ++ +
Sbjct: 828 RKQEELLRKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAAR---LRHEEEERKR 878
Query: 250 QDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESP 309
++L + + + + ++ A+ +Q+ + +A++ S+S WG++S
Sbjct: 879 KEL--------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS--TWGQQSN 928
Query: 310 AQA 312
A
Sbjct: 929 TTA 931
Score = 52.4 bits (124), Expect = 5e-07
Identities = 35/121 (28%), Positives = 69/121 (57%), Gaps = 7/121 (5%)
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQREAEEAE-REERKRLESQREAEWKKEEERLRLE 166
P +T G ++L++LE+ +A K ++E EAE R +R+ E +R+ E ++++E + L
Sbjct: 707 PLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LR 764
Query: 167 EEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQS 226
+Q+EE +R+ EE A+R+ EE L+ + E+E EE+ + E + +++
Sbjct: 765 RQQEEERKRREEEELARRKQEEALRRQR----EQEIALRRQREEEERQQQEEALRRLEER 820
Query: 227 K 227
+
Sbjct: 821 R 821
Score = 45.4 bits (106), Expect = 6e-05
Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
E+ A R R + + +A RR + E + ++E ++ QEEE + E
Sbjct: 793 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE--- 849
Query: 116 KIGAKKLRKLEEKQARKAQREAE-EAEREERKRLESQREAEWKKEEERLRLEEEQKEEEE 174
+ R+LEE + R + A E EERKR +E E ++++E +R ++Q+E
Sbjct: 850 ----EAQRRLEENRLRMEEEAARLRHEEEERKR----KELEVQRQKELMRQRQQQQEALR 901
Query: 175 RKAREEQAQR 184
R +++Q Q+
Sbjct: 902 RLQQQQQQQQ 911
Score = 43.1 bits (100), Expect = 3e-04
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 32/164 (19%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E EE + RR + R + +RR Q + + EE A +EEE + E L
Sbjct: 803 EEEERQQQEEALRRLEERRREEEERRKQEELLRK--QEEEAAKWAREEEEAQRRLEENRL 860
Query: 114 SGKIGAKKLRKLEEKQARK---AQREAE-----EAEREERKRLESQREAE---------- 155
+ A +LR EE++ RK QR+ E + ++E +RL+ Q++ +
Sbjct: 861 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920
Query: 156 --WKKE--------EERLRLEEEQK--EEEERKAREEQAQREHE 187
W ++ + L L E QK EE ER+ REEQ +++ E
Sbjct: 921 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 964
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 12/174 (6%)
Query: 27 RAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWA 86
R Q L L A+ E E R +R+++L + Q Q+ A R
Sbjct: 846 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 905
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGK--IGAKKLRKLEEKQARKAQREAEEAEREE 144
+ + + + L ++ T + + +++KLEE++ R+ + E +RE
Sbjct: 906 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 965
Query: 145 RKRLESQREAE------W----KKEEERLRLEEEQKEEEERKAREEQAQREHEE 188
K L+ Q++ + W K L E Q+EE + +++Q Q++H++
Sbjct: 966 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1019
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 62.8 bits (151), Expect = 4e-10
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 35/193 (18%)
Query: 48 AQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQ-----RVAWAEADENEEEAVILAQEE 102
A+ LE E A R +R + R + RR Q R E EEE + ++E
Sbjct: 753 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 812
Query: 103 EGVEKPAETHLSGKIGAKKLRKLEEKQARK-AQREAEEAEREERKR------LESQRE-- 153
E + + E +I ++ R+ EE+Q ++ A R EE REE +R L Q E
Sbjct: 813 EALRRQREQ----EIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
Query: 154 AEWKKEEE---------RLRLEEE----QKEEEERKAREEQAQREHEEYLKLKEAFVVEE 200
A+W +EEE RLR+EEE + EEEERK +E + QR+ E + ++ ++
Sbjct: 869 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ----QQ 924
Query: 201 EGVGETMTEEQSQ 213
E + ++Q Q
Sbjct: 925 EALRRLQQQQQQQ 937
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/188 (28%), Positives = 95/188 (50%), Gaps = 28/188 (14%)
Query: 50 PGPL-----EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG 104
PGP + E+ +A + RR+ + ++A+R + E ++E ++ Q+EE
Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERRE--AEMRAKREEEERKRQEELRRQQEEILRRQQEEE 797
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQ-ARKAQREAEEAEREER--KRLESQR--EAEWKKE 159
++ E L+ + + LR+ E++ A + QRE EE +++E +RLE +R E E +K+
Sbjct: 798 RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 857
Query: 160 EERLRLEEE------------QKEEEERKAR--EEQAQREHEEYLKLKEAFVVEEEGVGE 205
EE LR +EE Q+ EE + R EE A+ HEE + ++ V+ + E
Sbjct: 858 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ--KE 915
Query: 206 TMTEEQSQ 213
M + Q Q
Sbjct: 916 LMRQRQQQ 923
Score = 54.7 bits (130), Expect = 1e-07
Identities = 53/243 (21%), Positives = 117/243 (48%), Gaps = 26/243 (10%)
Query: 71 GSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQA 130
G L+ ++ ++ A+ ++ EA + A+ EE K E + +++ + ++++
Sbjct: 741 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ---EEILRRQQEEE 797
Query: 131 RKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE-EQAQREHEEY 189
RK + E E A R++ + L QRE E +R EEE+++++E R E+ +RE EE
Sbjct: 798 RKRREEEELARRKQEEALRRQREQEIALRRQR---EEEERQQQEEALRRLEERRREEEER 854
Query: 190 LKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRI 249
K +E +EE + EE+ E ++++++ + E+ A LR ++ +
Sbjct: 855 RKQEELLRKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAAR---LRHEEEERKR 905
Query: 250 QDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESP 309
++L + + + + ++ A+ +Q+ + +A++ S+S WG++S
Sbjct: 906 KEL--------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS--TWGQQSN 955
Query: 310 AQA 312
A
Sbjct: 956 TTA 958
Score = 52.4 bits (124), Expect = 5e-07
Identities = 35/121 (28%), Positives = 69/121 (57%), Gaps = 7/121 (5%)
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQREAEEAE-REERKRLESQREAEWKKEEERLRLE 166
P +T G ++L++LE+ +A K ++E EAE R +R+ E +R+ E ++++E + L
Sbjct: 734 PLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LR 791
Query: 167 EEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQS 226
+Q+EE +R+ EE A+R+ EE L+ + E+E EE+ + E + +++
Sbjct: 792 RQQEEERKRREEEELARRKQEEALRRQR----EQEIALRRQREEEERQQQEEALRRLEER 847
Query: 227 K 227
+
Sbjct: 848 R 848
Score = 45.4 bits (106), Expect = 6e-05
Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
E+ A R R + + +A RR + E + ++E ++ QEEE + E
Sbjct: 820 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE--- 876
Query: 116 KIGAKKLRKLEEKQARKAQREAE-EAEREERKRLESQREAEWKKEEERLRLEEEQKEEEE 174
+ R+LEE + R + A E EERKR +E E ++++E +R ++Q+E
Sbjct: 877 ----EAQRRLEENRLRMEEEAARLRHEEEERKR----KELEVQRQKELMRQRQQQQEALR 928
Query: 175 RKAREEQAQR 184
R +++Q Q+
Sbjct: 929 RLQQQQQQQQ 938
Score = 43.1 bits (100), Expect = 3e-04
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 32/164 (19%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E EE + RR + R + +RR Q + + EE A +EEE + E L
Sbjct: 830 EEEERQQQEEALRRLEERRREEEERRKQEELLRK--QEEEAAKWAREEEEAQRRLEENRL 887
Query: 114 SGKIGAKKLRKLEEKQARK---AQREAE-----EAEREERKRLESQREAE---------- 155
+ A +LR EE++ RK QR+ E + ++E +RL+ Q++ +
Sbjct: 888 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947
Query: 156 --WKKE--------EERLRLEEEQK--EEEERKAREEQAQREHE 187
W ++ + L L E QK EE ER+ REEQ +++ E
Sbjct: 948 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 991
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 12/174 (6%)
Query: 27 RAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWA 86
R Q L L A+ E E R +R+++L + Q Q+ A R
Sbjct: 873 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 932
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGK--IGAKKLRKLEEKQARKAQREAEEAEREE 144
+ + + + L ++ T + + +++KLEE++ R+ + E +RE
Sbjct: 933 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 992
Query: 145 RKRLESQREAE------W----KKEEERLRLEEEQKEEEERKAREEQAQREHEE 188
K L+ Q++ + W K L E Q+EE + +++Q Q++H++
Sbjct: 993 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1046
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 62.8 bits (151), Expect = 4e-10
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 35/193 (18%)
Query: 48 AQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQ-----RVAWAEADENEEEAVILAQEE 102
A+ LE E A R +R + R + RR Q R E EEE + ++E
Sbjct: 732 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 791
Query: 103 EGVEKPAETHLSGKIGAKKLRKLEEKQARK-AQREAEEAEREERKR------LESQRE-- 153
E + + E +I ++ R+ EE+Q ++ A R EE REE +R L Q E
Sbjct: 792 EALRRQREQ----EIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
Query: 154 AEWKKEEE---------RLRLEEE----QKEEEERKAREEQAQREHEEYLKLKEAFVVEE 200
A+W +EEE RLR+EEE + EEEERK +E + QR+ E + ++ ++
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ----QQ 903
Query: 201 EGVGETMTEEQSQ 213
E + ++Q Q
Sbjct: 904 EALRRLQQQQQQQ 916
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/188 (28%), Positives = 95/188 (50%), Gaps = 28/188 (14%)
Query: 50 PGPL-----EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG 104
PGP + E+ +A + RR+ + ++A+R + E ++E ++ Q+EE
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERRE--AEMRAKREEEERKRQEELRRQQEEILRRQQEEE 776
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQ-ARKAQREAEEAEREER--KRLESQR--EAEWKKE 159
++ E L+ + + LR+ E++ A + QRE EE +++E +RLE +R E E +K+
Sbjct: 777 RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 836
Query: 160 EERLRLEEE------------QKEEEERKAR--EEQAQREHEEYLKLKEAFVVEEEGVGE 205
EE LR +EE Q+ EE + R EE A+ HEE + ++ V+ + E
Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ--KE 894
Query: 206 TMTEEQSQ 213
M + Q Q
Sbjct: 895 LMRQRQQQ 902
Score = 54.7 bits (130), Expect = 1e-07
Identities = 53/243 (21%), Positives = 117/243 (48%), Gaps = 26/243 (10%)
Query: 71 GSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQA 130
G L+ ++ ++ A+ ++ EA + A+ EE K E + +++ + ++++
Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ---EEILRRQQEEE 776
Query: 131 RKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE-EQAQREHEEY 189
RK + E E A R++ + L QRE E +R EEE+++++E R E+ +RE EE
Sbjct: 777 RKRREEEELARRKQEEALRRQREQEIALRRQR---EEEERQQQEEALRRLEERRREEEER 833
Query: 190 LKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRI 249
K +E +EE + EE+ E ++++++ + E+ A LR ++ +
Sbjct: 834 RKQEELLRKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAAR---LRHEEEERKR 884
Query: 250 QDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESP 309
++L + + + + ++ A+ +Q+ + +A++ S+S WG++S
Sbjct: 885 KEL--------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS--TWGQQSN 934
Query: 310 AQA 312
A
Sbjct: 935 TTA 937
Score = 52.4 bits (124), Expect = 5e-07
Identities = 35/121 (28%), Positives = 69/121 (57%), Gaps = 7/121 (5%)
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQREAEEAE-REERKRLESQREAEWKKEEERLRLE 166
P +T G ++L++LE+ +A K ++E EAE R +R+ E +R+ E ++++E + L
Sbjct: 713 PLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LR 770
Query: 167 EEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQS 226
+Q+EE +R+ EE A+R+ EE L+ + E+E EE+ + E + +++
Sbjct: 771 RQQEEERKRREEEELARRKQEEALRRQR----EQEIALRRQREEEERQQQEEALRRLEER 826
Query: 227 K 227
+
Sbjct: 827 R 827
Score = 45.4 bits (106), Expect = 6e-05
Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
E+ A R R + + +A RR + E + ++E ++ QEEE + E
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE--- 855
Query: 116 KIGAKKLRKLEEKQARKAQREAE-EAEREERKRLESQREAEWKKEEERLRLEEEQKEEEE 174
+ R+LEE + R + A E EERKR +E E ++++E +R ++Q+E
Sbjct: 856 ----EAQRRLEENRLRMEEEAARLRHEEEERKR----KELEVQRQKELMRQRQQQQEALR 907
Query: 175 RKAREEQAQR 184
R +++Q Q+
Sbjct: 908 RLQQQQQQQQ 917
Score = 43.1 bits (100), Expect = 3e-04
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 32/164 (19%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E EE + RR + R + +RR Q + + EE A +EEE + E L
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRK--QEEEAAKWAREEEEAQRRLEENRL 866
Query: 114 SGKIGAKKLRKLEEKQARK---AQREAE-----EAEREERKRLESQREAE---------- 155
+ A +LR EE++ RK QR+ E + ++E +RL+ Q++ +
Sbjct: 867 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 156 --WKKE--------EERLRLEEEQK--EEEERKAREEQAQREHE 187
W ++ + L L E QK EE ER+ REEQ +++ E
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 970
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 12/174 (6%)
Query: 27 RAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWA 86
R Q L L A+ E E R +R+++L + Q Q+ A R
Sbjct: 852 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGK--IGAKKLRKLEEKQARKAQREAEEAEREE 144
+ + + + L ++ T + + +++KLEE++ R+ + E +RE
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Query: 145 RKRLESQREAE------W----KKEEERLRLEEEQKEEEERKAREEQAQREHEE 188
K L+ Q++ + W K L E Q+EE + +++Q Q++H++
Sbjct: 972 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 62.8 bits (151), Expect = 4e-10
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 35/193 (18%)
Query: 48 AQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQ-----RVAWAEADENEEEAVILAQEE 102
A+ LE E A R +R + R + RR Q R E EEE + ++E
Sbjct: 732 AKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE 791
Query: 103 EGVEKPAETHLSGKIGAKKLRKLEEKQARK-AQREAEEAEREERKR------LESQRE-- 153
E + + E +I ++ R+ EE+Q ++ A R EE REE +R L Q E
Sbjct: 792 EALRRQREQ----EIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
Query: 154 AEWKKEEE---------RLRLEEE----QKEEEERKAREEQAQREHEEYLKLKEAFVVEE 200
A+W +EEE RLR+EEE + EEEERK +E + QR+ E + ++ ++
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQ----QQ 903
Query: 201 EGVGETMTEEQSQ 213
E + ++Q Q
Sbjct: 904 EALRRLQQQQQQQ 916
Score = 58.9 bits (141), Expect = 6e-09
Identities = 54/188 (28%), Positives = 95/188 (50%), Gaps = 28/188 (14%)
Query: 50 PGPL-----EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG 104
PGP + E+ +A + RR+ + ++A+R + E ++E ++ Q+EE
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERRE--AEMRAKREEEERKRQEELRRQQEEILRRQQEEE 776
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQ-ARKAQREAEEAEREER--KRLESQR--EAEWKKE 159
++ E L+ + + LR+ E++ A + QRE EE +++E +RLE +R E E +K+
Sbjct: 777 RKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 836
Query: 160 EERLRLEEE------------QKEEEERKAR--EEQAQREHEEYLKLKEAFVVEEEGVGE 205
EE LR +EE Q+ EE + R EE A+ HEE + ++ V+ + E
Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ--KE 894
Query: 206 TMTEEQSQ 213
M + Q Q
Sbjct: 895 LMRQRQQQ 902
Score = 54.7 bits (130), Expect = 1e-07
Identities = 53/243 (21%), Positives = 117/243 (48%), Gaps = 26/243 (10%)
Query: 71 GSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQA 130
G L+ ++ ++ A+ ++ EA + A+ EE K E + +++ + ++++
Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ---EEILRRQQEEE 776
Query: 131 RKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE-EQAQREHEEY 189
RK + E E A R++ + L QRE E +R EEE+++++E R E+ +RE EE
Sbjct: 777 RKRREEEELARRKQEEALRRQREQEIALRRQR---EEEERQQQEEALRRLEERRREEEER 833
Query: 190 LKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRI 249
K +E +EE + EE+ E ++++++ + E+ A LR ++ +
Sbjct: 834 RKQEELLRKQEEEAAKWAREEE------EAQRRLEENRLRMEEEAAR---LRHEEEERKR 884
Query: 250 QDLLAEGTITGVIDDRGKFIYITPEELAAVANFIRQRGRVSIAELAQASNSLIAWGRESP 309
++L + + + + ++ A+ +Q+ + +A++ S+S WG++S
Sbjct: 885 KEL--------EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSS--TWGQQSN 934
Query: 310 AQA 312
A
Sbjct: 935 TTA 937
Score = 52.4 bits (124), Expect = 5e-07
Identities = 35/121 (28%), Positives = 69/121 (57%), Gaps = 7/121 (5%)
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQREAEEAE-REERKRLESQREAEWKKEEERLRLE 166
P +T G ++L++LE+ +A K ++E EAE R +R+ E +R+ E ++++E + L
Sbjct: 713 PLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LR 770
Query: 167 EEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQS 226
+Q+EE +R+ EE A+R+ EE L+ + E+E EE+ + E + +++
Sbjct: 771 RQQEEERKRREEEELARRKQEEALRRQR----EQEIALRRQREEEERQQQEEALRRLEER 826
Query: 227 K 227
+
Sbjct: 827 R 827
Score = 45.4 bits (106), Expect = 6e-05
Identities = 35/130 (26%), Positives = 63/130 (48%), Gaps = 12/130 (9%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
E+ A R R + + +A RR + E + ++E ++ QEEE + E
Sbjct: 799 EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE--- 855
Query: 116 KIGAKKLRKLEEKQARKAQREAE-EAEREERKRLESQREAEWKKEEERLRLEEEQKEEEE 174
+ R+LEE + R + A E EERKR +E E ++++E +R ++Q+E
Sbjct: 856 ----EAQRRLEENRLRMEEEAARLRHEEEERKR----KELEVQRQKELMRQRQQQQEALR 907
Query: 175 RKAREEQAQR 184
R +++Q Q+
Sbjct: 908 RLQQQQQQQQ 917
Score = 43.1 bits (100), Expect = 3e-04
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 32/164 (19%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E EE + RR + R + +RR Q + + EE A +EEE + E L
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRK--QEEEAAKWAREEEEAQRRLEENRL 866
Query: 114 SGKIGAKKLRKLEEKQARK---AQREAE-----EAEREERKRLESQREAE---------- 155
+ A +LR EE++ RK QR+ E + ++E +RL+ Q++ +
Sbjct: 867 RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 156 --WKKE--------EERLRLEEEQK--EEEERKAREEQAQREHE 187
W ++ + L L E QK EE ER+ REEQ +++ E
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRE 970
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/174 (21%), Positives = 73/174 (41%), Gaps = 12/174 (6%)
Query: 27 RAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWA 86
R Q L L A+ E E R +R+++L + Q Q+ A R
Sbjct: 852 REEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQ 911
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGK--IGAKKLRKLEEKQARKAQREAEEAEREE 144
+ + + + L ++ T + + +++KLEE++ R+ + E +RE
Sbjct: 912 QQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL 971
Query: 145 RKRLESQREAE------W----KKEEERLRLEEEQKEEEERKAREEQAQREHEE 188
K L+ Q++ + W K L E Q+EE + +++Q Q++H++
Sbjct: 972 MKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQ 1025
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 62.4 bits (150), Expect = 5e-10
Identities = 43/161 (26%), Positives = 85/161 (52%), Gaps = 22/161 (13%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q Q++ +++ E E+E + QEE+ +++ +T + G ++ + E+++ + Q
Sbjct: 249 QVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ 308
Query: 135 ----REAEEAEREERKRLESQREAEWK-------------KEEERLRLEEEQ--KEEEER 175
RE EE RE+ +++ Q E W+ K+EE++ +EEQ K+EE+
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQV 368
Query: 176 KAREEQAQREHEEYLKLKEAFVVEEEGVG---ETMTEEQSQ 213
+ +EEQ +++ E+ K +E +EE +G E M E++ Q
Sbjct: 369 RKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ 409
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 15/174 (8%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q G + +E + G + + + ++ Q R + E EE+ + ++EE V+K
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ---VQKQEEQVQKQ 253
Query: 109 AETHLSGKIGAKK----LRKLEE---KQARKAQREAEEAEREERKRLESQREAEWKKEEE 161
E + ++ +R+ EE KQ + ++E + E+EE+ R ++E + +++EE
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR---EQEEQMREQEE 310
Query: 162 RLRLEEEQKEEEERK--AREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
++R +EEQ E+E + +EEQ + E+ + KE +EE +GE + Q Q
Sbjct: 311 QMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ 364
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/168 (23%), Positives = 83/168 (49%), Gaps = 21/168 (12%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q G + +E + G + + + ++Q Q + + EE+ + ++EE V+K
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ---MGEQEEQVQKQ 246
Query: 109 AETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEE 168
E +++K EE+ R+ EE RE+ +++ Q E K++E+ + E+
Sbjct: 247 EE----------QVQKQEEQM-----RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQT 291
Query: 169 QKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVG---ETMTEEQSQ 213
++EE+ + +EEQ + + E+ + +E +EE +G E M E++ Q
Sbjct: 292 GEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ 339
Score = 52.8 bits (125), Expect = 4e-07
Identities = 37/152 (24%), Positives = 79/152 (51%), Gaps = 7/152 (4%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
+E + G + + R+ +++ Q R + E EE+ + ++EE + + E
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ---MGKQEEQMWEQKEQMWEQ 343
Query: 116 KIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQK-EEEE 174
K K + +Q + Q++ E+ ++E + ++E + +K+EE++R +EEQ E++E
Sbjct: 344 KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQM--RKQEEQMRKQEEQMRKQEEQMGEQKE 401
Query: 175 RKAREEQAQREHEEYL-KLKEAFVVEEEGVGE 205
+ +++ RE EE + + KE +EE +GE
Sbjct: 402 QMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Score = 52.0 bits (123), Expect = 7e-07
Identities = 38/144 (26%), Positives = 77/144 (53%), Gaps = 15/144 (10%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q + + +V E E+E + +E+EG + E + + G ++ E++ + +
Sbjct: 144 QVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEG-----QVREQEGQMGE 196
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQ--KEEEERKAREEQAQREHEEYLKL 192
+E + E+EE+ ++E + +K+EE++ +EEQ K+EE+ +EEQ Q++ E+ K
Sbjct: 197 QEGQMGEQEEQM---GEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ 253
Query: 193 KEAFVVEEEGV---GETMTEEQSQ 213
+E +EE + E M E++ Q
Sbjct: 254 EEQMRKQEEQMREQEEQMREQEEQ 277
Score = 50.8 bits (120), Expect = 2e-06
Identities = 37/146 (25%), Positives = 77/146 (52%), Gaps = 12/146 (8%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q + + +V E E+E + +E+EG + E + + G ++ E++ + +
Sbjct: 151 QVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEG-----QMGEQEGQMGE 203
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQ--KEEEERKAREEQAQREHEEYLKL 192
+E + E+EE+ + + ++ E +EE++R +EEQ ++EE+ + +EEQ Q++ E+ K
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGE---QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ 260
Query: 193 KEAFVVEEEGVGETMTEEQSQSFLTE 218
+E +EE + E + Q TE
Sbjct: 261 EEQMREQEEQMREQEEQMLKQKEQTE 286
Score = 49.7 bits (117), Expect = 3e-06
Identities = 33/139 (23%), Positives = 79/139 (56%), Gaps = 6/139 (4%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAET-HLSGKIGAKKLRKLEEKQARKA 133
Q + + +V E E+E + QE + E+ + G++G ++ ++ E++ +
Sbjct: 158 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQE-EQMGEQEEQMQ 216
Query: 134 QREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLK 193
++E + E+EE+ R + ++ E +EE+ + EE+ +++EE+ ++E+ RE EE ++ +
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGE--QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ 274
Query: 194 EAFVVEEEGVGETMTEEQS 212
E +++++ +T EEQ+
Sbjct: 275 EEQMLKQK--EQTEQEEQT 291
Score = 49.3 bits (116), Expect = 4e-06
Identities = 39/172 (22%), Positives = 88/172 (51%), Gaps = 15/172 (8%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q G + +E + + + R+ +++ Q + E EE+ + ++EE ++K
Sbjct: 162 QEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ---MGEQEEQMQKQ 218
Query: 109 AETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEE 168
E + +K + +Q + Q++ E+ +++E + ++E + +++EE++R +EE
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM--RKQEEQMREQEEQMREQEE 276
Query: 169 QK-EEEERKAREEQA------QREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
Q +++E+ +EEQ RE EE ++ +E + E+E E M E++ Q
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE---EQMREQEEQ 325
Score = 47.8 bits (112), Expect = 1e-05
Identities = 41/165 (24%), Positives = 78/165 (47%), Gaps = 5/165 (3%)
Query: 50 PGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPA 109
P P E + G+ R + + Q R Q E + E +E+EG +
Sbjct: 47 PLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 106
Query: 110 ETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQ 169
E + + G + ++ + ++ RE E RE+ ++ Q E + +++E ++R +E Q
Sbjct: 107 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQ 165
Query: 170 KEEEERKAREEQAQ-REHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E+E + RE++ Q RE E ++ +E + E+EG M E++ Q
Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEG---QMGEQEEQ 207
Score = 47.8 bits (112), Expect = 1e-05
Identities = 33/139 (23%), Positives = 70/139 (50%), Gaps = 5/139 (3%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q + + +V E E+E + +E+EG + E + + G + ++ + ++
Sbjct: 130 QVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 187
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
RE E E+ ++ Q E ++EE+ + EE+ E+EE+ ++E+ E EE ++ +E
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 195 AFVVEEEGVGETMTEEQSQ 213
V ++E E M +++ Q
Sbjct: 248 EQVQKQE---EQMRKQEEQ 263
Score = 44.3 bits (103), Expect = 1e-04
Identities = 31/114 (27%), Positives = 62/114 (54%), Gaps = 7/114 (6%)
Query: 90 ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLE 149
E +EE ++ E+ ++ + L K+ K+ +E Q R+ + + E E + R
Sbjct: 15 ELQEELQLVETEKSEIQLHIK-ELKRKLETDKIPLPQEGQVREQEGQVREQEGQVR---- 69
Query: 150 SQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ-REHEEYLKLKEAFVVEEEG 202
++E + +++E ++R +E Q E+E + RE++ Q RE E ++ +E V E+EG
Sbjct: 70 -EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
Score = 44.3 bits (103), Expect = 1e-04
Identities = 35/148 (23%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q + + +V E E+E + +E+EG + E + + G + ++ + ++
Sbjct: 102 QVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 159
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQ---------KEEEERKAREEQAQRE 185
RE E RE+ ++ Q E + +++E ++R +E Q ++EE+ +EEQ Q++
Sbjct: 160 REQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
Query: 186 HEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E+ + +E +EE +GE + Q Q
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Score = 43.9 bits (102), Expect = 2e-04
Identities = 29/127 (22%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q + + +V E E+E + +E+EG + E + + G + ++ + ++
Sbjct: 123 QVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
RE E RE+ ++ Q ++EE+ EE+ +++EE+ +E+ R+ EE + +E
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE 240
Query: 195 AFVVEEE 201
V ++E
Sbjct: 241 EQVQKQE 247
Score = 42.4 bits (98), Expect = 5e-04
Identities = 24/125 (19%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKL 125
+ +G + + + W + ++ ++ + ++EE ++K E ++RK
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE----------QVRKQ 371
Query: 126 EEKQARKAQ--REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ 183
EE+ ++ + R+ EE R++ +++ Q+E +++E+ EE+ E++E+ ++E+
Sbjct: 372 EEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHM 431
Query: 184 REHEE 188
E +E
Sbjct: 432 GEQKE 436
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/103 (27%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Query: 101 EEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEE 160
E + + P E + + G + ++ + ++ RE E RE+ ++ Q E + +++E
Sbjct: 42 ETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQE 100
Query: 161 ERLRLEEEQKEEEERKAREEQAQ-REHEEYLKLKEAFVVEEEG 202
++R +E Q E+E + RE++ Q RE E ++ +E V E+EG
Sbjct: 101 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 143
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/139 (23%), Positives = 67/139 (48%), Gaps = 8/139 (5%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q + + +V E E+E + +E+EG + E + + G + ++ + ++
Sbjct: 88 QVREQEGQVREQEGQVREQEGQV--REQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 145
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
RE E RE+ ++ Q E + +++E ++R +E Q E+E + RE++ Q +E
Sbjct: 146 REQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE-----G 199
Query: 195 AFVVEEEGVGETMTEEQSQ 213
+EE +GE + Q Q
Sbjct: 200 QMGEQEEQMGEQEEQMQKQ 218
Score = 36.2 bits (82), Expect = 0.039
Identities = 27/81 (33%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
Query: 124 KLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEE-QKEEEERKAREEQA 182
+L+EK A + Q E + E E+ + +E + K E +++ L +E Q E+E + RE++
Sbjct: 8 ELKEKNA-ELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG 66
Query: 183 Q-REHEEYLKLKEAFVVEEEG 202
Q RE E ++ +E V E+EG
Sbjct: 67 QVREQEGQVREQEGQVREQEG 87
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 62.0 bits (149), Expect = 7e-10
Identities = 48/151 (31%), Positives = 83/151 (54%), Gaps = 11/151 (7%)
Query: 98 LAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWK 157
+ +E + + K +E LS A + +K +E++A + +R EE E+E ++R E ++ +
Sbjct: 895 IQKEYDALVKSSEELLS----ALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKE 950
Query: 158 KEEERLRLEEEQK---EEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
+EE R++LE E K EEEERK RE+ +R E ++ + A EEE + + E++ +
Sbjct: 951 EEERRMKLEMEAKRKQEEEERKKREDDEKRIQAE-VEAQLARQKEEESQQQAVLEQERRD 1009
Query: 215 FLTEFINYIKQSKVVLLEDLA-SQVGLRTQD 244
E I QS+ L+ D A + + LR D
Sbjct: 1010 --RELALRIAQSEAELISDEAQADLALRRND 1038
Score = 48.5 bits (114), Expect = 8e-06
Identities = 53/181 (29%), Positives = 87/181 (48%), Gaps = 21/181 (11%)
Query: 90 ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK----AQREAEEAEREER 145
+ EEEA L + +E +EK + + K+ RK EE++ K A+R+ EE ER++R
Sbjct: 918 QQEEEAERLRRIQEEMEKERKRREEDE---KRRRKEEEERRMKLEMEAKRKQEEEERKKR 974
Query: 146 KRLESQREAEWKKEEERLRLEEEQKE---EEERKARE---EQAQREHEEYLKLKEAFVV- 198
+ E + +AE + + R + EE Q++ E+ER+ RE AQ E E +A +
Sbjct: 975 EDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLAL 1034
Query: 199 -EEEGVGETMTEEQSQSFLTEFIN------YIKQSKVVLLEDLASQVGLRTQDTINRIQD 251
+G MT EQ ++EF++ K + DL+ +DTIN D
Sbjct: 1035 RRNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCD 1094
Query: 252 L 252
+
Sbjct: 1095 I 1095
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 9e-10
Identities = 45/158 (28%), Positives = 87/158 (55%), Gaps = 12/158 (7%)
Query: 65 RRRRDLGSRLQAQRRAQRVA-WAEADE-NEEEAVILAQEEEGVEKPAETHLSGKIGAKKL 122
+R+ + R Q +R+ Q W + ++ E+E I QE++ + + H KI ++
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
Query: 123 RKLEEKQARKAQ--REAEEAERE-----ERKRLESQREAEWKKEEERLRLEEEQKEEEER 175
R+ +E+ R+ + RE EE R+ E++++ Q E W++EE+ EE+ +E+EE+
Sbjct: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK 517
Query: 176 KAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
R+E+ RE EE ++ +E + E+E E M E++ +
Sbjct: 518 MWRQEEKIREQEEKIREQEEKIREQE---EMMQEQEEK 552
Score = 60.8 bits (146), Expect = 1e-09
Identities = 38/131 (29%), Positives = 74/131 (56%), Gaps = 7/131 (5%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R + + R Q W + ++ E+ I QEE+ + + H +K+R+ EEK R+
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ----EEKIREQEEKMWRQ 521
Query: 133 AQ--REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYL 190
+ RE EE RE+ +++ Q E +++EE++ +EE+ +E+E+ R+E+ RE EE +
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEM-MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580
Query: 191 KLKEAFVVEEE 201
+ ++ + E+E
Sbjct: 581 REQKEKIREQE 591
Score = 58.9 bits (141), Expect = 6e-09
Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 18/167 (10%)
Query: 52 PLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAET 111
P + + A + + + ++LQAQ + W ++ +EE + ++EE +++ E
Sbjct: 259 PQQQLQAEADHLGKELQSVSAKLQAQVEENEL-WNRLNQQQEEK--MWRQEEKIQEWEE- 314
Query: 112 HLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKE 171
K+++ EEK RE EE RE+ +++ Q E W+KEE+ R EE E
Sbjct: 315 ---------KIQEQEEKI-----REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 172 EEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
+EE+ R E+ E EE ++ E + E+E + E + Q + + E
Sbjct: 361 KEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 407
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/143 (27%), Positives = 75/143 (52%), Gaps = 12/143 (8%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRK 124
R+ + + + RR + + W E +E E E+E + + E +K+R+
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMW-EKEEKIRELEEKMHEQEKIREQEEKRQE----EEKIRE 407
Query: 125 LEEKQARKAQR-EAEEAEREERKRLESQREAEWKKEE-----ERLRLEEEQKEEEERKAR 178
E++Q ++A+ EE RE+ +++ Q + W++EE E++R EEE+++E+E R
Sbjct: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR-EEEKRQEQEEMWR 466
Query: 179 EEQAQREHEEYLKLKEAFVVEEE 201
+E+ RE EE + KE +E+
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEK 489
Score = 55.8 bits (133), Expect = 5e-08
Identities = 40/145 (27%), Positives = 75/145 (51%), Gaps = 21/145 (14%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
+ RR + + W + ++ + ++ ++EE + + E + +K+R+LEEK + +
Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE---EKIRELEEKMHEQEK 391
Query: 135 -REAEEAEREERKRLESQREAE-----WKKE------EERLRLEE------EQKEEEERK 176
RE EE +EE K E ++ E W++E EE++R +E E+K E+ K
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 451
Query: 177 AREEQAQREHEEYLKLKEAFVVEEE 201
REE+ ++E EE + +E +EE
Sbjct: 452 IREEEKRQEQEEMWRQEEKIREQEE 476
Score = 55.5 bits (132), Expect = 6e-08
Identities = 41/164 (25%), Positives = 86/164 (52%), Gaps = 21/164 (12%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQ-----RRAQRVAWAEADENEEEAVILAQEEEGVEK 107
+ +E + + + D +++ Q R+ +++ E E+E I QEE +++
Sbjct: 490 IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM-MQE 548
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQ---REAEEAEREERKRLESQREAEWKKEE---- 160
E K+G ++ + E+++ R+ + RE EE RE+++++ Q E W++EE
Sbjct: 549 QEE-----KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE 603
Query: 161 -ERLRLEEEQK--EEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
E + E+E+K E+EE+ +E+ +E EE ++ +E + E+E
Sbjct: 604 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647
Score = 54.7 bits (130), Expect = 1e-07
Identities = 38/157 (24%), Positives = 77/157 (49%), Gaps = 6/157 (3%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q + +E + + + R+ +++ Q +++ E E+E + QEE+ E+
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQE--EKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 109 AETHLSGKIGAKKLRKLEEKQARKAQREA----EEAEREERKRLESQREAEWKKEEERLR 164
KI ++ + E+K+ + Q E EE RE+ + ++ Q E W++EE+
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
Query: 165 LEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
EE+ +E+EE+ R+E+ E E L+ +E + E +
Sbjct: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 52.0 bits (123), Expect = 7e-07
Identities = 36/153 (23%), Positives = 85/153 (55%), Gaps = 7/153 (4%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEE---GVEKPAETHLSGKIGAKK 121
R++ + + + +++ ++V E +++E I QEE+ EK E + +K
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 122 LRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQ-KEEEERKAREE 180
+R+ EE + ++ E+ E+ + + ++E + +++EE++R ++E+ +E+EE+ +E
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 181 QAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
+ RE EE ++ +E + E+E E M E++ +
Sbjct: 599 EKIREQEEMMQEQEEKMWEQE---EKMCEQEEK 628
Score = 49.7 bits (117), Expect = 3e-06
Identities = 41/149 (27%), Positives = 77/149 (51%), Gaps = 15/149 (10%)
Query: 77 QRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKI---GAKKLRKLEEKQARKA 133
Q + +++ E E+E + QEE EK + ++ +K+R+LEE K
Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376
Query: 134 Q--REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEE------ERKAREEQAQ-R 184
+ RE EE E+ K E + E ++EEE++R +E+++E+E E K RE++ + R
Sbjct: 377 EKIRELEEKMHEQEKIREQE---EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 433
Query: 185 EHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E E+ + +E + E+E + E ++ +
Sbjct: 434 EQEKKMWRQEEKIHEQEKIREEEKRQEQE 462
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/120 (27%), Positives = 62/120 (51%), Gaps = 12/120 (10%)
Query: 81 QRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEK--QARKAQREAE 138
Q E +E +E + ++EE + + E K +K+R+ EEK + + RE E
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK---EKIREQEEKIWEQEEKIREQE 605
Query: 139 EAEREERKRLESQREA-----EWKKEEERLRLEEEQK--EEEERKAREEQAQREHEEYLK 191
E +E+ +++ Q E E +E+E +E+K E+E R ++E+ +EH+E+L+
Sbjct: 606 EMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 34.3 bits (77), Expect = 0.15
Identities = 35/168 (20%), Positives = 82/168 (48%), Gaps = 10/168 (5%)
Query: 89 DENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL-RKLEEKQARKAQREAEEAEREERKR 147
DE +E QE+ + + ++ + ++ K+L RKLE + Q++ + K
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 273
Query: 148 LESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETM 207
L+S + EE +++EE+ R+E+ +E EE ++ +E + E+E E +
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKI 330
Query: 208 TEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAE 255
E++ + E + + K+ K+ E++ + ++ + R+++++ E
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWE----KEEKMRRLEEMMWE 374
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/174 (28%), Positives = 89/174 (51%), Gaps = 26/174 (14%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q G + +E + + +R R+ L+ Q + R + + E+E + QEE+ E+
Sbjct: 305 QEGKMREQEEKMWRQEKRLREQEKELREQEKELR---EQKELREQEEQMQEQEEKMWEQE 361
Query: 109 AETHLSGKIGAKKLRKLEEKQARKAQR--EAEEAEREERKRLESQREAEWKKEEERLRLE 166
+K+R+ EEK R+ +R E E+ RE+ +++ Q E W +++ERLR +
Sbjct: 362 -----------EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW-EQDERLREK 409
Query: 167 EEQKEEEER------KAREEQAQREHEEYLKLKEAFVVEEEGVGE---TMTEEQ 211
EE+ E+E+ K REE+ +E E+ + +E + EEE + E M EE+
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEE 463
Score = 55.5 bits (132), Expect = 6e-08
Identities = 35/159 (22%), Positives = 82/159 (51%), Gaps = 5/159 (3%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGV----EKPAETHLSGKIGAK 120
R+ +L + + R+ + W + + E+ + ++EE + ++ E + K
Sbjct: 276 RQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEK 335
Query: 121 KLRKLEEKQARKAQ-REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE 179
+LR+ +E + ++ Q +E EE E+ +++ Q E W++EE E++ +E+E++ +
Sbjct: 336 ELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQ 395
Query: 180 EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
E+ E +E L+ KE + E+E + E + + + + + E
Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Score = 52.8 bits (125), Expect = 4e-07
Identities = 35/140 (25%), Positives = 72/140 (51%), Gaps = 4/140 (2%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKI--GAKKLRKLEEKQARKAQR 135
R+ +R+ E E+E + QE+ E+ E K K+LR+ EE+ + ++
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
Query: 136 --EAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLK 193
E EE RE+ +++ Q E W++E++ E++ +++EER +++ RE EE ++ +
Sbjct: 357 MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQ 416
Query: 194 EAFVVEEEGVGETMTEEQSQ 213
E + E + E ++ +
Sbjct: 417 EKMWEQVEKMREEKKMQEQE 436
Score = 52.0 bits (123), Expect = 7e-07
Identities = 38/128 (29%), Positives = 66/128 (51%), Gaps = 12/128 (9%)
Query: 93 EEAVILAQEEEGVEKPAETHLSGKIGAKKLRK----LEEKQARKAQREA---EEAEREER 145
+E + LA+ E+ +E L+ K +KL + L + Q Q E EE RE+
Sbjct: 231 QEKLPLAESEK-----SEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQE 285
Query: 146 KRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGE 205
K++ Q E W++EE E + +E+EE+ R+E+ RE E+ L+ +E + E++ + E
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345
Query: 206 TMTEEQSQ 213
+ Q Q
Sbjct: 346 QEEQMQEQ 353
Score = 52.0 bits (123), Expect = 7e-07
Identities = 46/185 (24%), Positives = 82/185 (44%), Gaps = 37/185 (20%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKP 108
Q + +E R + R R+ R++ Q + W + ++ EE + QE
Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKM----WEQVEKMREEKKMQEQE------- 436
Query: 109 AETHLSGKIGAKKLRKLEEK--------QARKAQREAEEAEREERKRLESQREAEWKKEE 160
KK R EEK + K RE EE RE+ ++++ Q E W++EE
Sbjct: 437 -----------KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 161 -----ERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGV--GETMTEEQSQ 213
+RL ++E+ E+E+ +E+ E EE ++ +E +E+ + E M E++ Q
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 545
Query: 214 SFLTE 218
+ E
Sbjct: 546 MWEQE 550
Score = 51.2 bits (121), Expect = 1e-06
Identities = 33/150 (22%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETH------LSGKIGAKKLRKLE 126
R + R + W + ++ ++ + +EE +EK + K+ ++ +
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 127 EKQARKAQ---REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ 183
EK+ R+ + RE EE +E+ ++++ Q E W++EE+ EE+ E+EE+ +E+
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 184 REHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E + + KE E+ + +EQ +
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEE 684
Score = 51.2 bits (121), Expect = 1e-06
Identities = 41/173 (23%), Positives = 85/173 (49%), Gaps = 15/173 (8%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE R R ++ R+ ++ Q +++ E E+E + QEE+ E+ +
Sbjct: 587 EEERMREREKKMREEEEMMREQE--EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 116 KIGAKKLRKLEEKQARKAQREA--EEAEREERKRLESQREAEWKKEEERLRLEEEQKE-- 171
+ ++ K+ E+Q Q+E E + +E+++++ Q E W++E+ + +E++K+
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704
Query: 172 ------EEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
EEE E+ RE EE ++ +E + E+E E M E++ + + E
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQE---EKMQEQEEEMWEQE 754
Score = 50.4 bits (119), Expect = 2e-06
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 2/150 (1%)
Query: 81 QRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEA 140
++ W + E+E + QEE+ ++ + + KK ++ E+K + ++ EE
Sbjct: 530 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE 589
Query: 141 EREERKRLESQREAEWKKEEERLRLEEEQKEEEERKA--REEQAQREHEEYLKLKEAFVV 198
ER++ + E +++EE+++ +EE+ +E+E K +EE+ Q + E+ + +E
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE 649
Query: 199 EEEGVGETMTEEQSQSFLTEFINYIKQSKV 228
+EE + E + + L E +Q K+
Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Score = 50.1 bits (118), Expect = 3e-06
Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 18/151 (11%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADE-NEEEAVILAQEEEGVEKPAETHLSGKIGAKKLR 123
R +++L + + + + W + ++ E+E + QEE E+ + +K+R
Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQ----EQKMR 393
Query: 124 KLEEKQARKAQR--EAEEAEREERK---RLESQREAEWKKEEERLRLEEEQKEEEERKAR 178
EE+ + +R E EE RE+ K ++E RE + +E+E+ ++E+K +EE + R
Sbjct: 394 DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIR 453
Query: 179 E--------EQAQREHEEYLKLKEAFVVEEE 201
E E+ RE EE ++ +E + E+E
Sbjct: 454 EREKKMREEEETMREQEEKMQKQEENMWEQE 484
Score = 48.9 bits (115), Expect = 6e-06
Identities = 36/141 (25%), Positives = 70/141 (49%), Gaps = 7/141 (4%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKL 125
+ + + + Q R + W E DE E +E+E + + E K+ +K +
Sbjct: 381 QEKQMREQEQKMRDQEERMW-EQDERLREKEERMREQEKMWEQVE-----KMREEKKMQE 434
Query: 126 EEKQARKAQREAEEAER-EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQR 184
+EK+ R + + +E ER ER++ + E +++EE+++ +EE E+E K ++Q
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 185 EHEEYLKLKEAFVVEEEGVGE 205
E +E L +E +EE + E
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWE 515
Score = 48.1 bits (113), Expect = 1e-05
Identities = 39/138 (28%), Positives = 72/138 (52%), Gaps = 12/138 (8%)
Query: 85 WAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQR-EAEEAERE 143
W + E+E I QEE+ + + + G+ KK+ + E+ + ++ Q E EE R+
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRD---QEEMWGQ--EKKMWRQEKMREQEDQMWEQEEKMRD 555
Query: 144 ERKRLESQREAEWKKEEERLRL---EEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEE 200
+ +++ Q E KK +E+ + +EE+ EEER E+ RE EE ++ +E + E+
Sbjct: 556 QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 615
Query: 201 EGVGETMTEEQSQSFLTE 218
E E M E++ + + E
Sbjct: 616 E---EKMQEQEEKMWEQE 630
Score = 46.2 bits (108), Expect = 4e-05
Identities = 29/113 (25%), Positives = 60/113 (53%), Gaps = 4/113 (3%)
Query: 120 KKLRKLEEK--QARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKA 177
+K+++ EEK + K +++ +E E++ + + + E ++ E+++R EEE E+E K
Sbjct: 677 EKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKM 736
Query: 178 RE--EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKV 228
+E E+ Q + EE + +E +EE + E + + L E +Q K+
Sbjct: 737 QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKI 789
Score = 45.1 bits (105), Expect = 8e-05
Identities = 27/106 (25%), Positives = 55/106 (51%)
Query: 100 QEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKE 159
QE+E +++ E + KK ++ E+K + + EE+ RE K++ + E ++E
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 160 EERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGE 205
E+ EE+ +E+EE +E+ E EE + ++ ++E + E
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Score = 44.7 bits (104), Expect = 1e-04
Identities = 30/124 (24%), Positives = 57/124 (45%)
Query: 90 ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLE 149
E +E + ++EE + + + + KK E+ + ++ RE E+ REE + +
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 150 SQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTE 209
Q E ++EE+ EEE E+EE+ +E+ E + + KE E+ +
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 210 EQSQ 213
EQ +
Sbjct: 791 EQEE 794
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/178 (20%), Positives = 85/178 (47%), Gaps = 15/178 (8%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETH 112
+ EE + + ++ ++Q Q W + ++ +E+ + ++EE + + E
Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKM---WEQEEKMQEQEEKMWEQEEKMWEQEEKM 654
Query: 113 LSGKIGAKKLRKLEEKQARKAQREAEEAERE--ERKRLESQREAEWKK--EEERLRLEEE 168
+ ++ KL E + + Q + +E E + E++++E + + + KK ++E++R EE
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 169 QKEEEER--------KAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
+E E++ + +EE+ Q + E+ + +E +EE + E + Q L E
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772
Score = 43.5 bits (101), Expect = 2e-04
Identities = 38/148 (25%), Positives = 75/148 (50%), Gaps = 15/148 (10%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE + + ++ RD ++Q + +R+ E EEE + QEE+ ++K E
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEE---ERIREREKKMREEEETMREQEEK-MQKQEENMWEQ 483
Query: 116 KIGAKKLRKLEEKQAR----KAQREAEEAEREERKRLESQREAEWKKE-----EERLRLE 166
+ + ++L E++ + + +E EE E+ +++ Q E W +E +E++R +
Sbjct: 484 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM-WGQEKKMWRQEKMREQ 542
Query: 167 EEQKEEEERKAR-EEQAQREHEEYLKLK 193
E+Q E+E K R +EQ + EE ++ K
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKK 570
Score = 43.5 bits (101), Expect = 2e-04
Identities = 36/162 (22%), Positives = 81/162 (50%), Gaps = 7/162 (4%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE R ++ R+ ++ Q + + E EEE + QEE+ E+ +
Sbjct: 711 EEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE--MWEQEEKMWEQEEKMWEQQ 768
Query: 116 KIGAKKLRKLEEKQARKAQR--EAEEAEREERKRLESQREAEWKKEEERLRLEEEQK--E 171
++ +K + E ++ ++ ++ E EE R++ +++ Q E + + +EE++R +EE+ +
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE-KMRGQEEKMRGQEEKMWGQ 827
Query: 172 EEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
EE+ +EE+ + E+ +E + +G E M E++ +
Sbjct: 828 EEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEK 869
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/127 (28%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLE-----EKQARKAQ---REAE 138
E + +EE + E+E +EK + +K+R+ E EK+ R+ + RE E
Sbjct: 677 EKMQEQEEKI---WEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQE 733
Query: 139 EAEREERKRLESQREAEWKKEEERLRLEE---------EQKE--EEERKAREEQAQREHE 187
E +E+ ++++ Q E W++EE+ EE EQKE E K +E++ E E
Sbjct: 734 EKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 188 EYLKLKE 194
E ++ +E
Sbjct: 794 EKMRDQE 800
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/114 (28%), Positives = 63/114 (55%), Gaps = 10/114 (8%)
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAERE--E 144
E ++ +E+ I QEE+ + E + G+ +K+R EEK + ++ + E+ +
Sbjct: 779 EHEKMQEQEKIWEQEEK--MRDQEEKMRGQ--EEKMRGQEEKMRGQEEKMWGQEEKMWGQ 834
Query: 145 RKRLESQREAEWKKEE---ERLRLEEEQKEEEERKAR-EEQAQREHEEYLKLKE 194
+++ Q E W +EE E+++ +EE+ E+E K R +E+ RE EE ++ +E
Sbjct: 835 EEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQE 888
Score = 40.4 bits (93), Expect = 0.002
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 8/89 (8%)
Query: 120 KKLRKLEEKQARKAQ--REAEEAEREERKRLESQREAEWKKEEERLRLEE-----EQKEE 172
+K+R EEK + + R EE R + +++ Q E W +EE+ EE E+K E
Sbjct: 794 EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853
Query: 173 EERKAREEQAQREHEEYLKLKEAFVVEEE 201
E+ + +EE+ RE EE ++ +E + E+E
Sbjct: 854 EKMQGQEEK-MREQEEKMRGQEEKMREQE 881
Score = 39.3 bits (90), Expect = 0.005
Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 4/117 (3%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEE---EGVEKPAETHLSGKIGAKKLRKLEEKQAR 131
+ R + + E EEE ++ QEE E EK E +K+ + EEK
Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766
Query: 132 KAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEE 188
+ + ++ + E ++++ Q E W++EE+ EE+ + +EE+ +E+ R EE
Sbjct: 767 QQRLPEQKEKLWEHEKMQEQ-EKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 61.6 bits (148), Expect = 9e-10
Identities = 39/154 (25%), Positives = 81/154 (52%), Gaps = 16/154 (10%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAET-HLSGKIGAKKLR 123
R+ + + + RR + + W + ++ + ++ ++EE + + E H KI ++ +
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Query: 124 KLEEKQARKAQREAE---------EAEREERKRLESQREAEWKKEE-----ERLRLEEEQ 169
+ EE++ R+ ++ E E RE+ +++ Q E W++EE E++R EEE+
Sbjct: 460 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR-EEEK 518
Query: 170 KEEEERKAREEQAQREHEEYLKLKEAFVVEEEGV 203
++E+E R+E+ RE EE + KE +EE +
Sbjct: 519 RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKI 552
Score = 60.8 bits (146), Expect = 1e-09
Identities = 45/167 (26%), Positives = 83/167 (49%), Gaps = 18/167 (10%)
Query: 52 PLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAET 111
P + + A + + + ++LQAQ + W ++ +EE + ++EE +++ E
Sbjct: 320 PQQQLQAEADHLGKELQSVSAKLQAQVEENEL-WNRLNQQQEEK--MWRQEEKIQEWEE- 375
Query: 112 HLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKE 171
K+++ EEK RE EE RE+ +++ Q E W+KEE+ R EE E
Sbjct: 376 ---------KIQEQEEKI-----REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 421
Query: 172 EEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
+EE+ R+E+ E EE ++ E + E+E + E + Q + + E
Sbjct: 422 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 468
Score = 60.8 bits (146), Expect = 1e-09
Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 5/130 (3%)
Query: 77 QRRAQRVAWAEADENEEEAVILAQEE---EGVEKPAETHLSGKIGAKKLRKLEEK--QAR 131
+ + +++ E E+E + QEE E EK E + +K+R+ EEK +
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Query: 132 KAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLK 191
K RE EE RE+ + ++ Q E W++EE+ EE+ +E+EE+ R+E+ E E L+
Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 707
Query: 192 LKEAFVVEEE 201
+E + E +
Sbjct: 708 QQEEKMQEHQ 717
Score = 59.3 bits (142), Expect = 4e-09
Identities = 44/156 (28%), Positives = 81/156 (51%), Gaps = 17/156 (10%)
Query: 73 RLQAQRRAQRVAWAEADE-NEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQAR 131
R + + R Q W + ++ +E+E I QEE+ + + H +K+R+ EEK R
Sbjct: 527 RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ----EEKIREQEEKVWR 582
Query: 132 KAQ---------REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQA 182
+ + RE EE RE+ + + Q E ++EE+ EE+ +E+EE+ R+E+
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 183 QREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
RE E+ ++ +E + E+E E M E++ + + E
Sbjct: 643 IREQEKKIREQEEKIREQE---EMMQEQEEKMWEQE 675
Score = 58.2 bits (139), Expect = 1e-08
Identities = 42/155 (27%), Positives = 84/155 (54%), Gaps = 6/155 (3%)
Query: 65 RRRRDLGSRLQAQRRAQRVA-WAEADE-NEEEAVILAQEEEGVEKPAETHLSGKIGAKKL 122
+R+ + R Q +R+ Q W + ++ E+E I QEE+ + + H KI ++
Sbjct: 459 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEK 518
Query: 123 RKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAR--EE 180
R+ +E+ R+ ++ E+ E +K ++E + +K+EE++ +EE+ ++E K R EE
Sbjct: 519 RQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEE 578
Query: 181 QAQREHEEYLKLKEAFVVEEEGV--GETMTEEQSQ 213
+ R+ E+ + +E +EE + E MT+EQ +
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Score = 56.6 bits (135), Expect = 3e-08
Identities = 39/145 (26%), Positives = 74/145 (51%), Gaps = 21/145 (14%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
+ RR + + W + ++ + ++ ++EE + + E + +K+R+LEEK + +
Sbjct: 396 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKIRELEEKMHEQEK 452
Query: 135 -REAEEAEREERKRLESQREAE-----WKKEEERLRLEEEQKEEEER------------K 176
RE EE +EE K E ++ E W++EE+ EE+ +E+EE+ K
Sbjct: 453 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Query: 177 AREEQAQREHEEYLKLKEAFVVEEE 201
REE+ ++E EE + +E +EE
Sbjct: 513 IREEEKRQEQEEMWRQEEKIREQEE 537
Score = 56.6 bits (135), Expect = 3e-08
Identities = 38/141 (26%), Positives = 73/141 (51%), Gaps = 19/141 (13%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R + +R+ Q W + ++ E+ I Q+E+ E+ +K+RK EEK R+
Sbjct: 514 REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ-----------EEKIRKQEEKMWRQ 562
Query: 133 AQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKL 192
EE ++ +++ Q E W++EE+ EE+ +E+EE+ +E+ +E EE +
Sbjct: 563 -----EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 193 KEAFVVEEEGVGETMTEEQSQ 213
+E + E+E E M E++ +
Sbjct: 618 QEEKMCEQE---EKMQEQEEK 635
Score = 56.2 bits (134), Expect = 4e-08
Identities = 39/153 (25%), Positives = 84/153 (54%), Gaps = 12/153 (7%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRK 124
R++ + + + R+ + W + ++ ++ + ++EE V + E + +K+R+
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQE---EKIRE 596
Query: 125 LEEK---QARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQ 181
EEK Q Q + E+ +E K E +E + +++EE++R +EE+ E+E+K RE++
Sbjct: 597 QEEKIREQEEMTQEQEEKMGEQEEKMCE--QEEKMQEQEEKMRRQEEKIREQEKKIREQE 654
Query: 182 AQ-REHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
+ RE EE ++ +E + E+E E M E++ +
Sbjct: 655 EKIREQEEMMQEQEEKMWEQE---EKMCEQEEK 684
Score = 52.4 bits (124), Expect = 5e-07
Identities = 38/146 (26%), Positives = 75/146 (51%), Gaps = 12/146 (8%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRK 124
R+ + + + R + W + ++ E+ + ++EE + + E + +K+ +
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQE---EKMGE 617
Query: 125 LEEK---QARKAQREAEEAEREERKRLESQ---REAEWK-KEEERLRLEEEQK--EEEER 175
EEK Q K Q + E+ R+E K E + RE E K +E+E + E+E+K E+EE+
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Query: 176 KAREEQAQREHEEYLKLKEAFVVEEE 201
+E+ +E EE ++ +E + E+E
Sbjct: 678 MCEQEEKMQEQEEKMRRQEEKMWEQE 703
Score = 50.8 bits (120), Expect = 2e-06
Identities = 41/153 (26%), Positives = 75/153 (49%), Gaps = 10/153 (6%)
Query: 49 QPGPLEPEEPRAGGRPRRRRDLGSRLQAQR---RAQRVAWAEADEN--EEEAVILAQEE- 102
Q + +E + + + R+ +++ Q R Q E +E E+E + QEE
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 103 --EGVEKPAETHLSGKIGAKKLRKLEEK--QARKAQREAEEAEREERKRLESQREAEWKK 158
E EK + KK+R+ EEK + + +E EE E+ +++ Q E ++
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688
Query: 159 EEERLRLEEEQKEEEERKAREEQAQREHEEYLK 191
EE+ R EE+ E+E R ++E+ +EH+E+L+
Sbjct: 689 EEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 48.9 bits (115), Expect = 6e-06
Identities = 35/135 (25%), Positives = 74/135 (54%), Gaps = 15/135 (11%)
Query: 73 RLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARK 132
R Q ++R + E ++ +E+ + ++EE + + E K+R+ EEK R+
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE----------KIREQEEKMWRQ 503
Query: 133 AQREAEEAE-REERKRLESQREAEWKKEEERLRLEEE-QKEEEERKAREEQAQREHEEYL 190
++ E+ + REE KR Q + E ++EE++R +EE +++E+ +EE+ +++ E+
Sbjct: 504 EEKIHEQEKIREEEKR---QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 191 KLKEAFVVEEEGVGE 205
+ +E +EE + E
Sbjct: 561 RQEEKMHDQEEKIRE 575
Score = 33.1 bits (74), Expect = 0.33
Identities = 33/147 (22%), Positives = 71/147 (48%), Gaps = 6/147 (4%)
Query: 89 DENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL-RKLEEKQARKAQREAEEAEREERKR 147
DE +E QE+ + + ++ + ++ K+L RKLE + Q++ + K
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEI--QLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 334
Query: 148 LESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETM 207
L+S + EE +++EE+ R+E+ +E EE ++ +E + E+E E +
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQE---EKI 391
Query: 208 TEEQSQSFLTEFINYIKQSKVVLLEDL 234
E++ + E + + K+ K+ E++
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEM 418
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 60.8 bits (146), Expect = 1e-09
Identities = 34/105 (32%), Positives = 58/105 (55%)
Query: 90 ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLE 149
E EE +EEE K E + +K +K +E + RK + E E+ + +RK+ +
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKK 70
Query: 150 SQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
+ E E ++EEE EEE+KEE R+ ++++ +R+ EE K K+
Sbjct: 71 EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 56.2 bits (134), Expect = 4e-08
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 2/102 (1%)
Query: 100 QEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKE 159
+ EE E E GK K+ K +EK+ +K +E E+ + +E + + +R+ + KKE
Sbjct: 12 ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKE 71
Query: 160 EERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
EE EEE++EEEE K EE+ + + K + EEE
Sbjct: 72 EEER--EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111
Score = 53.5 bits (127), Expect = 2e-07
Identities = 25/95 (26%), Positives = 58/95 (61%)
Query: 100 QEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKE 159
++++ E+ ET + + K+ ++ E+++ ++ ++E ++ +E KR E + E + +K
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 160 EERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
+ + + EEE++EEEE + EE+ + E EE + K+
Sbjct: 65 KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99
Score = 49.7 bits (117), Expect = 3e-06
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 5/109 (4%)
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEE--KQARKAQREAEEAEREE 144
E +E EE+ ++ + K E K K+ K EE K+ RK +++ EE EREE
Sbjct: 18 ETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 145 RKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLK 193
+ E + + E +KEE R R ++K++ RK EE+ +++ K K
Sbjct: 78 EEEEEEEEKEEEEKEEGRRR---KKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 49.3 bits (116), Expect = 4e-06
Identities = 30/94 (31%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 120 KKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE 179
KK +K +E + + E EE E +E KR E ++E +KE+++ + KE E+RK +E
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKK-----KTKETEKRKEKE 56
Query: 180 EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E+ ++ + K KE EEE E +E+ +
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEE 90
Score = 47.8 bits (112), Expect = 1e-05
Identities = 30/126 (23%), Positives = 65/126 (51%), Gaps = 26/126 (20%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E EE + G R +R++ + +++ + E ++ +E+ +EEE
Sbjct: 20 EEEEEKEGKRKEKRKEKRKEKEKKKKTK-----ETEKRKEK-----EEEE---------- 59
Query: 114 SGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEE 173
KK ++ +K+ + +RE EE E EE K E + E +K++++ R +EE++E++
Sbjct: 60 ------KKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKK 113
Query: 174 ERKARE 179
+++ R+
Sbjct: 114 KKRRRK 119
Score = 45.8 bits (107), Expect = 5e-05
Identities = 30/91 (32%), Positives = 50/91 (54%), Gaps = 12/91 (13%)
Query: 123 RKLEEKQARKAQREAEEAEREE-------RKRLESQREAEWKK-----EEERLRLEEEQK 170
+K ++K+ + E EE E EE KR E ++E E KK E+ + + EEE+K
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 171 EEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
+ +RK ++E+ +RE EE + +E E+E
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKE 92
Score = 35.8 bits (81), Expect = 0.051
Identities = 27/121 (22%), Positives = 56/121 (46%), Gaps = 14/121 (11%)
Query: 33 QEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENE 92
+E EE G + + + +E + + +R + +R+ +R E +E E
Sbjct: 17 EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEERE 76
Query: 93 EEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQR 152
EE +EEE EK E G+ K+ +K +R+ EE E+++++R ++++
Sbjct: 77 EE-----EEEEEEEKEEEEKEEGR---------RRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Query: 153 E 153
+
Sbjct: 123 K 123
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 60.5 bits (145), Expect = 2e-09
Identities = 47/165 (28%), Positives = 82/165 (49%), Gaps = 16/165 (9%)
Query: 52 PLEPEEPRAGGRPRRRRDLGSRLQAQRRAQ-RVAWAEADENEEEAVILAQEEEGVEKPAE 110
PL PE P + + +D + L+ + + R AE + N+ +++ ++EE + + E
Sbjct: 147 PLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEE 206
Query: 111 THLSGKIGAKKLRKLEEKQARKAQR--EAEEAEREERKRLESQREAEWKKEEERLRLEEE 168
+LR+ EE+ + +R E EE RE+ +RL Q E ++EE EE
Sbjct: 207 ----------RLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEER 256
Query: 169 QKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E+EER +E+ RE EE L +E + E+E E + E++ +
Sbjct: 257 LCEQEERLCEQEERLREQEERLHEQEERLCEQE---ERLREQEER 298
Score = 56.6 bits (135), Expect = 3e-08
Identities = 69/261 (26%), Positives = 109/261 (41%), Gaps = 26/261 (9%)
Query: 21 LTRSRGRAASAGQEPLHNEELAGAGRVAQ----PGPLEPEEPRAGGRPRRRRDLGSRLQA 76
L RS + + EPL E AG +V Q L E G + + + L
Sbjct: 133 LGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192
Query: 77 QRRAQRVAWAEADEN--EEEAVILAQEE---EGVEKPAETHLSGKIGAKKLRKLEEKQAR 131
R Q E +E E+E + QEE E E+ E + ++L + EE+
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 132 KAQREAEEAER--EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEY 189
+R E+ ER E+ +RL Q E ++EE EE +E+EER +E+ RE EE
Sbjct: 253 HEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEER 312
Query: 190 L--------KLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVV-------LLEDL 234
L + +E +E+ G+ E+ + L + +Q +++ +E+L
Sbjct: 313 LCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEEL 372
Query: 235 ASQVGLRTQDTINRIQDLLAE 255
Q LR QD Q+ L E
Sbjct: 373 LEQERLRQQDERLWQQETLQE 393
Score = 37.0 bits (84), Expect = 0.023
Identities = 40/142 (28%), Positives = 68/142 (47%), Gaps = 10/142 (7%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
+E R + R R+ RL Q +R+ E E+E + QEE E+ E L
Sbjct: 260 QEERLCEQEERLREQEERLHEQE--ERLCEQEERLREQEERLCEQEERLREQ--EERLCE 315
Query: 116 KIGAKKLRKLEEKQARKAQREAEEAEREE-RKRLESQREAEWKK---EEERLRLEEEQKE 171
+ ++LR+ EE+ + + +E EE K LE +R E ++ E ERL E E+
Sbjct: 316 Q--EERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELL 373
Query: 172 EEERKAREEQAQREHEEYLKLK 193
E+ER ++++ + E +L+
Sbjct: 374 EQERLRQQDERLWQQETLQELE 395
Score = 35.8 bits (81), Expect = 0.051
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 11/180 (6%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETH 112
L +E R + R + RL+ Q +R+ E E+E + QEE E+
Sbjct: 271 LREQEERLHEQEERLCEQEERLREQE--ERLCEQEERLREQEERLCEQEERLREQEERLC 328
Query: 113 LSGKI-GAKKLRKLEEKQARKAQREAEEAEREERKRL-----ESQREAEWKKEEERLRLE 166
K+ G ++L + EK + +R+ E+ ER+RL E + ++++ERL +
Sbjct: 329 EQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQ 388
Query: 167 EEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQS 226
E +E E + E + E L E G E E +S L + + +K+S
Sbjct: 389 ETLQELERLRELERMLELGWE---ALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKS 445
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 60.5 bits (145), Expect = 2e-09
Identities = 44/152 (28%), Positives = 81/152 (53%), Gaps = 12/152 (7%)
Query: 52 PLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAET 111
P+ P +P AG R +RL A++R Q E +E E + E ++ E
Sbjct: 583 PVTPSKPMAGTTDREE---ATRLLAEKRRQAREQREREEQERRL-----QAERDKRMREE 634
Query: 112 HLSGKIGAKKLRKLEEKQARKAQ-REAEEAEREERKRLESQRE---AEWKKEEERLRLEE 167
L+ + A+ R+ E ++ + + RE +AE+EE++RL+ Q+E A ++E ER RLE
Sbjct: 635 QLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLER 694
Query: 168 EQKEEEERKAREEQAQREHEEYLKLKEAFVVE 199
E+ +++ + R+E+ +R E + +++ V E
Sbjct: 695 EKHFQQQEQERQERRKRLEEIMKRTRKSEVSE 726
Score = 45.8 bits (107), Expect = 5e-05
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 119 AKKLRKLEEKQARKAQREAEEAEREERKRLES-QREAEWKKEEERLRLEEEQKEEEERKA 177
A+K R+ E++ R+ Q +AER++R R E REAE + E E E ++EE+E +
Sbjct: 604 AEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREA---EARRREEQEARE 660
Query: 178 REEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSF 215
+ + Q E E K KE E E+ + F
Sbjct: 661 KAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHF 698
Score = 44.3 bits (103), Expect = 1e-04
Identities = 45/191 (23%), Positives = 73/191 (38%), Gaps = 22/191 (11%)
Query: 43 GAGRVAQPGPLEPEEPRAG--GRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQ 100
G G P P P A GR RR+ + A + NE+E+ A
Sbjct: 485 GPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPAS 544
Query: 101 EE------------EGVEKPAETHLSGKI------GAKKLRKLEEKQARKAQREAEEAER 142
+ + PAET + A + + + EA
Sbjct: 545 PAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLA 604
Query: 143 EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEG 202
E+R++ QRE E ++E RL+ E +++ EE+ ARE +A+ E E + +E E+
Sbjct: 605 EKRRQAREQRERE--EQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKA 662
Query: 203 VGETMTEEQSQ 213
E +E+ Q
Sbjct: 663 QAEQEEQERLQ 673
Score = 44.3 bits (103), Expect = 1e-04
Identities = 38/135 (28%), Positives = 66/135 (48%), Gaps = 17/135 (12%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHL 113
E E R +R R+ +A+ RA+R A EA EE+ A+E+ E+ + L
Sbjct: 618 EQERRLQAERDKRMREEQLAREAEARAEREA--EARRREEQE---AREKAQAEQEEQERL 672
Query: 114 SGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEE 173
++ EE +A R EEAER+ +R + ++ E +++E R RLEE K
Sbjct: 673 Q--------KQKEEAEA----RSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTR 720
Query: 174 ERKAREEQAQREHEE 188
+ + E + +++ +E
Sbjct: 721 KSEVSETKQKQDSKE 735
Score = 42.4 bits (98), Expect = 5e-04
Identities = 35/101 (34%), Positives = 55/101 (54%), Gaps = 15/101 (14%)
Query: 119 AKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKE------EERLRLEEEQKEE 172
A +L + +QAR+ QRE EE ER RL+++R+ ++E E R E E +
Sbjct: 599 ATRLLAEKRRQARE-QREREEQER----RLQAERDKRMREEQLAREAEARAEREAEARRR 653
Query: 173 EERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
EE++AR E+AQ E EE +L++ +EE + E + Q
Sbjct: 654 EEQEAR-EKAQAEQEEQERLQKQ---KEEAEARSREEAERQ 690
Score = 41.2 bits (95), Expect = 0.001
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 30/187 (16%)
Query: 28 AASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAE 87
+ G P +E + + GP P RP RR +Q V ++
Sbjct: 72 SGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRR-------SSQPSPTAVPASD 124
Query: 88 ADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKR 147
+ ++E V+K E H K + EE+ A ++A E+EE+ +
Sbjct: 125 SPPTKQE----------VKKAGERHKLAK------ERREERAKYLAAKKAVWLEKEEKAK 168
Query: 148 LESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAF-VVEEEGVGET 206
+++ + E R RLEE++ + E+R+A E+ QR+ E K KE + + V +T
Sbjct: 169 ALREKQLQ----ERRRRLEEQRLKAEQRRAALEERQRQKLE--KNKERYEAAIQRSVKKT 222
Query: 207 MTEEQSQ 213
E + Q
Sbjct: 223 WAEIRQQ 229
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/146 (26%), Positives = 66/146 (45%), Gaps = 15/146 (10%)
Query: 52 PLEPEEP--RAGGRPRRRRDLGSRLQAQRRAQRV-AWAEADENEEEAVILAQEEEGVEKP 108
PLEPE P + G RP ++ +A+ R A D A+ +P
Sbjct: 65 PLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRD---------ARPPRRSSQP 115
Query: 109 AETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEE 168
+ T + K E K+A + + A+E REER + + ++A W ++EE+ + E
Sbjct: 116 SPTAVPASDSPPT--KQEVKKAGERHKLAKE-RREERAKYLAAKKAVWLEKEEKAKALRE 172
Query: 169 QKEEEERKAREEQAQREHEEYLKLKE 194
++ +E R+ EEQ + + L+E
Sbjct: 173 KQLQERRRRLEEQRLKAEQRRAALEE 198
Score = 40.0 bits (92), Expect = 0.003
Identities = 25/90 (27%), Positives = 50/90 (55%), Gaps = 2/90 (2%)
Query: 126 EEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQRE 185
+ ++A + E RE+R+R E +R + + ++R+R E+ +E E R RE +A+R
Sbjct: 595 DREEATRLLAEKRRQAREQREREEQERRLQ-AERDKRMREEQLAREAEARAEREAEARRR 653
Query: 186 HEEYLKLK-EAFVVEEEGVGETMTEEQSQS 214
E+ + K +A E+E + + E +++S
Sbjct: 654 EEQEAREKAQAEQEEQERLQKQKEEAEARS 683
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 59.7 bits (143), Expect = 3e-09
Identities = 37/113 (32%), Positives = 66/113 (58%), Gaps = 5/113 (4%)
Query: 106 EKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRL 165
E +E H S ++ + L +LE++++ ++ E E E EER+ E + E E +KEEE
Sbjct: 2219 EVESEEHFSEEMESL-LDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEE 2277
Query: 166 EEEQKEEEERKAREEQAQREH----EEYLKLKEAFVVEEEGVGETMTEEQSQS 214
++ +KEEEE+K ++++ ++E EE + KE + EEE + EE+ +S
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEES 2330
Score = 55.5 bits (132), Expect = 6e-08
Identities = 40/133 (30%), Positives = 75/133 (56%), Gaps = 6/133 (4%)
Query: 69 DLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEK 128
++ S L + + ++ E +E EEE +EEE V + E + G +K + EE+
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEE---EREEEEVREEEEERKEEEEGEEKQVEKEEE 2285
Query: 129 QARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEE 188
+ +K ++E ++ E +E++ + ++E E EEE L +E+ EEEE + EE+ RE +E
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKE-EIMSEEETESLSDEE-EEEESCSLEEEVDRE-KE 2342
Query: 189 YLKLKEAFVVEEE 201
LK ++ F ++E+
Sbjct: 2343 ILKKEKQFKLQEQ 2355
Score = 50.8 bits (120), Expect = 2e-06
Identities = 40/153 (26%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADE--NEEEAVILAQEEEG--VEKPAETHLSGKIGAK 120
R++R L ++++ + E + + VIL EEEG E+ L + +
Sbjct: 2141 RKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKR 2200
Query: 121 KLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREE 180
K K +K K + +E E EE E + + +++E L EEE++ EEE + EE
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260
Query: 181 QAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
+ + E EE + EEEG + + +E+ +
Sbjct: 2261 EVREEEEERKE-------EEEGEEKQVEKEEEE 2286
Score = 47.8 bits (112), Expect = 1e-05
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERK 146
E +E EEE V +EE E+ E K +K +K +EK+ + Q + E E +E
Sbjct: 2253 EEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEI 2312
Query: 147 RLESQREA--EWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLK 193
E + E+ + ++EEE LEEE E+E +E+Q + + + L+
Sbjct: 2313 MSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLR 2361
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/156 (24%), Positives = 74/156 (47%), Gaps = 24/156 (15%)
Query: 56 EEPRAGGRPRRR-RDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLS 114
+E + G +P+ + ++++ + DE E++ + ++EEE E+ E
Sbjct: 2201 KEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEER--- 2257
Query: 115 GKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEE-- 172
EE++ R+ + E +E E E K++E + E + KK++E+ + E ++KEE
Sbjct: 2258 -----------EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306
Query: 173 --EERKAREEQA-----QREHEEYLKLKEAFVVEEE 201
+E EE+ + E EE L+E E+E
Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Score = 42.0 bits (97), Expect = 7e-04
Identities = 40/143 (27%), Positives = 70/143 (48%), Gaps = 6/143 (4%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQE-EEGVEKPAETHLSGKIGAKKLR 123
++R+ L + + R + + + E ILAQ+ EE ++ K A++L
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELE 1719
Query: 124 KLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ 183
+LE + +E EE +EE K +E +++ +EEE L + E+ EEE K +E+
Sbjct: 1720 ELEWDMEELSWKE-EELNQEEGKLVEEKKKL--AEEEEALAWQREKLSEEETKLAQEEEL 1776
Query: 184 --REHEEYLKLKEAFVVEEEGVG 204
+E E+ + KE EEE +G
Sbjct: 1777 LIQEKEKLAQHKEKMPEEEERLG 1799
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/148 (26%), Positives = 71/148 (47%), Gaps = 14/148 (9%)
Query: 74 LQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKA 133
LQ ++ + W + EN + Q+ + E+ + G +K +++ E+Q R
Sbjct: 1510 LQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQ-RHI 1568
Query: 134 QREAEEAE------REERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ--RE 185
Q E + A R E+KR +Q E + +EEE+L EE Q +EERK + + ++
Sbjct: 1569 QEEHKWARIHRKRARAEKKR--AQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQD 1626
Query: 186 HEEYLKLKEAFVVEEEGV---GETMTEE 210
E + + F +EE + GE +++E
Sbjct: 1627 DREMAQAEGKFAQKEETLAQRGEKLSQE 1654
Score = 37.4 bits (85), Expect = 0.017
Identities = 36/124 (29%), Positives = 55/124 (44%), Gaps = 20/124 (16%)
Query: 69 DLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEK 128
D ++ + R AW E E L QEEE + + E KL EE
Sbjct: 1465 DEWKQVHGETRKSWKAWKEEWEKR-----LLQEEEKLHQAGE----------KLSPEEEM 1509
Query: 129 QARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEE---QKEEEERKAREEQ--AQ 183
+ + EE ++ L S+ + + K+EE + LEEE + EE+E++ EEQ Q
Sbjct: 1510 LQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQ 1569
Query: 184 REHE 187
EH+
Sbjct: 1570 EEHK 1573
Score = 37.4 bits (85), Expect = 0.017
Identities = 26/101 (25%), Positives = 55/101 (54%), Gaps = 10/101 (9%)
Query: 81 QRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEA 140
+ ++W E + N+EE ++ ++++ E+ A + KL E++ + AQ E E
Sbjct: 1726 EELSWKEEELNQEEGKLVEEKKKLAEEEEAL-------AWQREKLSEEETKLAQEE--EL 1776
Query: 141 EREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQ 181
+E+++L +E + +EEERL + EQ E++ K +++
Sbjct: 1777 LIQEKEKLAQHKE-KMPEEEERLGRKREQLIEKKMKLAQKR 1816
Score = 37.0 bits (84), Expect = 0.023
Identities = 35/163 (21%), Positives = 75/163 (46%), Gaps = 25/163 (15%)
Query: 75 QAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
Q + +++A A +++ + E + +K G+ +++ KL +K+ +K
Sbjct: 1608 QLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKR-KKLA 1666
Query: 135 REAEEAEREERKRLES-------------------QRE--AEWKKEEERLRLEEEQKEEE 173
++ E+ REE K + QRE +W+++E LEE + + E
Sbjct: 1667 KKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDME 1726
Query: 174 ERKAREEQAQREHEEYLKLKEAFVVEEEGVG---ETMTEEQSQ 213
E +EE+ +E + ++ K+ EEE + E ++EE+++
Sbjct: 1727 ELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETK 1769
Score = 36.6 bits (83), Expect = 0.030
Identities = 39/127 (30%), Positives = 63/127 (49%), Gaps = 22/127 (17%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREA 137
+R Q + W E + LAQE E +E E LS K ++L + E K + ++ A
Sbjct: 1702 QREQNLDWQEKE--------LAQELEELEWDME-ELSWK--EEELNQEEGKLVEEKKKLA 1750
Query: 138 EEAEREERKRLESQREAEWKKEEERLRLEEEQK---EEEERKAREEQAQREHEEYLKLKE 194
EE E L QRE K EE +L +E++ +E+E+ A+ ++ E EE L K
Sbjct: 1751 EEEEA-----LAWQRE---KLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 195 AFVVEEE 201
++E++
Sbjct: 1803 EQLIEKK 1809
Score = 36.2 bits (82), Expect = 0.039
Identities = 36/120 (30%), Positives = 61/120 (50%), Gaps = 17/120 (14%)
Query: 97 ILAQEEEGVEKPAETHLSGKIGA----KKLRKLEEKQARKAQREAEE--------AEREE 144
ILAQ EE + + ET + K KKL ++E+ A+K ++ A+E A +
Sbjct: 1887 ILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQG 1946
Query: 145 RKRLESQREAEWKKEEERLRLEEEQKEEEERK---AREEQAQREHEEYLKLKEAFVVEEE 201
+KRL E + KEE+ L LE ++ EE+ + +E ++ E E + ++ VE+E
Sbjct: 1947 KKRLRG--ELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQE 2004
Score = 33.5 bits (75), Expect = 0.25
Identities = 46/192 (23%), Positives = 79/192 (41%), Gaps = 21/192 (10%)
Query: 64 PRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLR 123
P++ R + + + +R E + EE +A EE V K GK+ + R
Sbjct: 1400 PKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQ-----EGKLVMIE-R 1453
Query: 124 KLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ 183
+ +KA E ++ E RK ++ +E EW+K RL EEE+ + K E+
Sbjct: 1454 TPSWQDWKKAWDEWKQVHGETRKSWKAWKE-EWEK---RLLQEEEKLHQAGEKLSPEEEM 1509
Query: 184 REHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQ 243
+ ++ LK +E V E + E+Q K + V LE+ S+ G +
Sbjct: 1510 LQEDKKLKWEEWKQVWENMLSSKSKEQQ-----------YKDEEEVTLEEEVSREGEEKE 1558
Query: 244 DTINRIQDLLAE 255
+ Q + E
Sbjct: 1559 QQVTEEQRHIQE 1570
Score = 31.6 bits (70), Expect = 0.96
Identities = 33/135 (24%), Positives = 64/135 (47%), Gaps = 9/135 (6%)
Query: 53 LEPEEPRAGGRPRRRRDLGSR-LQAQRRAQRV----AWAEADENEEEAVILAQEEEGVEK 107
LE E R G ++ R +Q + + R+ A AE +EE + +EE+ ++
Sbjct: 1546 LEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQE 1605
Query: 108 PAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEE 167
+ + A+ K+ + AQ E + A++EE +QR + +E E+L +
Sbjct: 1606 ERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETL---AQRGEKLSQEAEKLAQKR 1662
Query: 168 EQKEEE-ERKAREEQ 181
++ ++ E+ AREE+
Sbjct: 1663 KKLAKKWEKVAREEE 1677
Score = 30.8 bits (68), Expect = 1.6
Identities = 37/158 (23%), Positives = 70/158 (44%), Gaps = 11/158 (6%)
Query: 56 EEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
EE +A + R L ++ ++V + E V + +E E+ S
Sbjct: 1346 EEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGN-----VTMGKEISKKEEKKTFQKSP 1400
Query: 116 KIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWK--KEEERLRLEEEQKEEE 173
K G K ++K E++ K +RE + ER+ + +E E K K+E +L + E +
Sbjct: 1401 KQGRKAVQK--ERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQ 1458
Query: 174 ERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQ 211
+ K ++ ++ H E K +A+ +EE + EE+
Sbjct: 1459 DWKKAWDEWKQVHGETRKSWKAW--KEEWEKRLLQEEE 1494
Score = 28.9 bits (63), Expect = 6.2
Identities = 34/148 (22%), Positives = 65/148 (43%), Gaps = 17/148 (11%)
Query: 121 KLRKLEEKQARKAQREAEEAER-----EERKRLESQREAEWKKEEERLRLEEEQKEEEER 175
K R+L +Q++ +E + +E+ ++ K+L ++ K + EE+ EEE +
Sbjct: 2107 KERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK 2166
Query: 176 KAR---------EEQAQREHEEYLK-LKEAFVVEEEGVGETMTEEQ--SQSFLTEFINYI 223
AR EE+ E EE + LK + +E +E+ SQ E +
Sbjct: 2167 LARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF 2226
Query: 224 KQSKVVLLEDLASQVGLRTQDTINRIQD 251
+ LL++L Q L +++ R ++
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEE 2254
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 58.9 bits (141), Expect = 6e-09
Identities = 58/236 (24%), Positives = 102/236 (43%), Gaps = 19/236 (8%)
Query: 45 GRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEG 104
G+++ P + EE G + +R A EA+E E I A++++
Sbjct: 231 GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERER---IKAEQDK- 286
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWK---KEEE 161
KI ++ R E++A +RE EAE ER R E +R AE + KEEE
Sbjct: 287 -----------KIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE 335
Query: 162 RLRLEEEQK-EEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFI 220
+ EE Q+ +EEE++A EE+ + + EE +E E + EEQ ++ E
Sbjct: 336 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Query: 221 NYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEEL 276
+ Q + E + ++ + + +D L + +++G + E+L
Sbjct: 396 KHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Score = 55.1 bits (131), Expect = 8e-08
Identities = 57/233 (24%), Positives = 111/233 (47%), Gaps = 25/233 (10%)
Query: 31 AGQEPLHNEELA-GAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEAD 89
+ +EP EE G+ ++ +E E+ R +RL+A+ R + A +
Sbjct: 234 SSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAER------ARLEAEERERIKAEQDKK 287
Query: 90 ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAER--EERKR 147
+E A I A+E+ ++ + +++R+ E++ A + QR EE +R EER+R
Sbjct: 288 IADERARIEAEEKAAAQERERREAEER---ERMREEEKRAAEERQRIKEEEKRAAEERQR 344
Query: 148 L--ESQREAEWK---KEEERLRLEEEQK----EEEERKAREEQAQREHEEYLKLKEAFVV 198
+ E +R AE + KEEE+ EE Q+ EEE+ K E++ ++ EE K+ +
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEE----KKHAMQ 400
Query: 199 EEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQD 251
E + GE + ++ ++ E + + +L+ + G + Q ++Q+
Sbjct: 401 ETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQE 453
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/131 (29%), Positives = 66/131 (50%), Gaps = 19/131 (14%)
Query: 90 ENEEEAVILAQEEEGVE----KPAETHLSGKIGAKKLRKLEEK-----QARKAQREAEEA 140
E++EE V+++ + + K E G K+EE+ +A +A+ EAEE
Sbjct: 218 ESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEER 277
Query: 141 ER----------EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYL 190
ER +ER R+E++ +A ++ E R E E+ EEE++A EE+ + + EE
Sbjct: 278 ERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKR 337
Query: 191 KLKEAFVVEEE 201
+E ++EE
Sbjct: 338 AAEERQRIKEE 348
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/85 (36%), Positives = 53/85 (62%), Gaps = 7/85 (8%)
Query: 123 RKLEEKQARKAQREAEEAEREERKRLESQREAEW---KKEEERLRLEEEQ----KEEEER 175
++LEE + R+ + E+EE E+ ++K+ E+ E E K+EE R LEEE+ +EE +R
Sbjct: 534 KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR 593
Query: 176 KAREEQAQREHEEYLKLKEAFVVEE 200
K REE+ +R +E ++ + A E+
Sbjct: 594 KLREEEEKRRLKEEIERRRAEAAEK 618
Score = 42.4 bits (98), Expect = 5e-04
Identities = 52/212 (24%), Positives = 83/212 (39%), Gaps = 37/212 (17%)
Query: 44 AGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEE 103
A R+A + EE A R RRRR RL+ Q++ + D+ E A +EE
Sbjct: 22 AERIAYQRNDDDEEEAA--RERRRRARQERLR-QKQEEESLGQVTDQVEVNAQNSVPDEE 78
Query: 104 GVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREE---------------RKRL 148
T + G A L +L ++ R+ +R E ER++ R+
Sbjct: 79 AKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQ 138
Query: 149 ESQREAEWKKEEERLRLEEEQKEEEERKA----------------REEQAQREHEEYLKL 192
E E ++EE+ +E+ E EE + ++E ++E EE K
Sbjct: 139 NDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP 198
Query: 193 KEAFVVE---EEGVGETMTEEQSQSFLTEFIN 221
K + E E V E TE Q ++ + N
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMSLKN 230
Score = 42.4 bits (98), Expect = 5e-04
Identities = 34/119 (28%), Positives = 61/119 (51%), Gaps = 7/119 (5%)
Query: 88 ADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKA-QREAEEAEREERK 146
A + +EA Q E G G+ +++ KL++KQ A + E + +REER+
Sbjct: 517 ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERR 576
Query: 147 RLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGE 205
++ + E K+EE +L E EEE+R+ +EE +R E K ++ + E+G+ +
Sbjct: 577 KVLEEEEQRRKQEEADRKLRE---EEEKRRLKEEIERRRAEAAEKRQK---MPEDGLSD 629
Score = 42.0 bits (97), Expect = 7e-04
Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 47/154 (30%)
Query: 81 QRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREA--- 137
Q+ W +A+EN++E +EEE EKP G IG ++ + E++ ++Q E
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEE--EKPKR----GSIGENQVEVMVEEKTTESQEETVVM 226
Query: 138 ----------------------------EEAEREERKRLESQREAEWKKEEERLRLEEEQ 169
E+ E E+++R E++R +E ER++ E+++
Sbjct: 227 SLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDK 286
Query: 170 KEE---------EERKAREEQAQREHEEYLKLKE 194
K EE+ A +E+ +RE EE +++E
Sbjct: 287 KI-ADERARIEAEEKAAAQERERREAEERERMRE 319
Score = 39.7 bits (91), Expect = 0.004
Identities = 47/191 (24%), Positives = 89/191 (46%), Gaps = 18/191 (9%)
Query: 27 RAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWA 86
RAA Q E+ A R ++ EE RA +R ++ + +R A+ A
Sbjct: 323 RAAEERQRIKEEEKRAAEERQR----IKEEEKRAAEERQRIKE-----EEKRAAEERQRA 373
Query: 87 EADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL-RKLEEK--QARKAQRE----AEE 139
A+E E+ V + + +E+ KI +K+ +K+E K +KAQ + A
Sbjct: 374 RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVL 433
Query: 140 AEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVE 199
++ E K + Q + E +E++ +EE K+E+ +K +++ + E + ++ K+ F
Sbjct: 434 KKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK--DKEPKEEVKSFMDRKKGFTEV 491
Query: 200 EEGVGETMTEE 210
+ GE MT +
Sbjct: 492 KSQNGEFMTHK 502
Score = 38.9 bits (89), Expect = 0.006
Identities = 30/141 (21%), Positives = 64/141 (45%), Gaps = 14/141 (9%)
Query: 86 AEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREER 145
A +E ++ + A E + P T S + +++++ + + ++E + R+ER
Sbjct: 101 ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN-DTAENETTEKEEKSESRQER 159
Query: 146 KRLE-------SQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVV 198
+E S ++ +W+ EE + ++E++EEEE K + E + ++
Sbjct: 160 YEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTES 219
Query: 199 EEEGV------GETMTEEQSQ 213
+EE V G+ +EE Q
Sbjct: 220 QEETVVMSLKNGQISSEEPKQ 240
Score = 36.6 bits (83), Expect = 0.030
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 12/126 (9%)
Query: 66 RRRDLGSRLQAQRR--AQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLR 123
RRR+L + + + R A+R+A+ D++EEEA E + + L K + L
Sbjct: 6 RRRELRRQKREEMRLEAERIAYQRNDDDEEEAA-----RERRRRARQERLRQKQEEESLG 60
Query: 124 KLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQ 183
++ ++ AQ + EE K + + E ++E LE + EE R+ R ++A
Sbjct: 61 QVTDQVEVNAQNSVPD---EEAKTTTTNTQVE--GDDEAAFLERLARREERRQKRLQEAL 115
Query: 184 REHEEY 189
+E+
Sbjct: 116 ERQKEF 121
Score = 36.2 bits (82), Expect = 0.039
Identities = 21/63 (33%), Positives = 34/63 (53%), Gaps = 6/63 (9%)
Query: 143 EERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEG 202
E R+ L Q+ E + E ER+ + +EEE A E+ +R +E L+ K+ EEE
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEE--AARERRRRARQERLRQKQ----EEES 58
Query: 203 VGE 205
+G+
Sbjct: 59 LGQ 61
Score = 36.2 bits (82), Expect = 0.039
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 15/120 (12%)
Query: 59 RAGGRPR---RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSG 115
R GGR + + +++A +R + + + EE L Q+++ E E
Sbjct: 512 RPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQ--EAALELEELK 569
Query: 116 KIGAKKLRKLEEKQARKAQREAEEA--EREERKRLESQREAEWKKEEERLRLEEEQKEEE 173
K ++ + LEE++ R+ Q EA+ E EE++RL K+E ER R E +K ++
Sbjct: 570 KKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL--------KEEIERRRAEAAEKRQK 621
Score = 34.7 bits (78), Expect = 0.11
Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 20/95 (21%)
Query: 114 SGKIGAKKLRKLEEKQARKAQR------EAEEAEREER-KRLESQR------------EA 154
+G+ KL+ E +R R EAE A + E KRLE R +
Sbjct: 495 NGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL 554
Query: 155 EWKKEEERLRLEE-EQKEEEERKAREEQAQREHEE 188
+ K++E L LEE ++K EE RK EE+ QR +E
Sbjct: 555 KQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 589
Score = 29.3 bits (64), Expect = 4.7
Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 8/90 (8%)
Query: 120 KKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKE-------- 171
+++R E+ A + + EE ER+R Q K+EEE L +Q E
Sbjct: 16 EEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVP 75
Query: 172 EEERKAREEQAQREHEEYLKLKEAFVVEEE 201
+EE K Q E ++ E EE
Sbjct: 76 DEEAKTTTTNTQVEGDDEAAFLERLARREE 105
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 58.5 bits (140), Expect = 7e-09
Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 25/160 (15%)
Query: 67 RRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEE---GVEKPAETHLSGKIGAKKLR 123
R++ R Q ++R +++ E E++ I QEEE EK E + +KLR
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 124 KLEEK----------QARKAQREAEEAEREERK------------RLESQREAEWKKEEE 161
++EEK Q K QR+ E+ + +E K ++ Q E W++EE+
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Query: 162 RLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
EE+ +E+EE+ R+E+ RE E L +E + E+E
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/144 (27%), Positives = 76/144 (52%), Gaps = 7/144 (4%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEE---EGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
R+ +++ E E+E + QEE E EK E +K+R+ EEK+ K
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
R+ E+ RE+ +++ Q E W++EE+ LEE +++EE+ E+ +E EE ++ +E
Sbjct: 410 RQ-EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 195 AFVVEEEGVGETMTEEQSQSFLTE 218
+ +E E + E++ +++ E
Sbjct: 469 EKIQRQE---EKIQEQEEKTWRQE 489
Score = 55.8 bits (133), Expect = 5e-08
Identities = 46/169 (27%), Positives = 85/169 (50%), Gaps = 19/169 (11%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQE--EEGVEKPAE 110
L+ E R G + + + ++LQAQ + W ++ +EE + +E +E EK E
Sbjct: 260 LQVEADRLG---KELQSVSAKLQAQVEENEL-WNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
Query: 111 THLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQK 170
L K+R+ EEK R+ EE E+ +++ Q + W++EE+ EE+ +
Sbjct: 316 QEL-------KIREQEEKMWRQ-----EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
Query: 171 EEEERKAREEQAQREHEEYL-KLKEAFVVEEEGVGETMTEEQSQSFLTE 218
E+EE+ R+E+ RE +E + + +E +EE + E + Q + + E
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Score = 51.6 bits (122), Expect = 9e-07
Identities = 43/174 (24%), Positives = 86/174 (49%), Gaps = 15/174 (8%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREA 137
R+ +++ E E+E I QEE+ + + H +K+R+ E+K R+
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ----EEKIREQEDKMWRQ----- 351
Query: 138 EEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFV 197
EE RE+ +++ Q E W++EE+ +E+ +E+EE R+E+ RE EE K +E
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE--KRQEKMW 409
Query: 198 VEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQD 251
+E + M E+ + E + ++ K+ LE++ + ++ ++Q+
Sbjct: 410 RQE----KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Score = 48.5 bits (114), Expect = 8e-06
Identities = 40/154 (25%), Positives = 78/154 (50%), Gaps = 18/154 (11%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGV----EKPAETHLSGKIGAKKLRKLEEK---QA 130
R + W + ++ E+ + ++E+ + EK E + +K+ + EEK Q
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD 380
Query: 131 RKAQREAEEAEREE---RKRLESQREAEWKKE------EERLRLEEEQ--KEEEERKARE 179
K Q + EE R+E R++ E ++E W++E +E++R +EE+ ++EE+ + E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 180 EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E Q + E+ +++E EEE + E + Q Q
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Score = 29.3 bits (64), Expect = 4.7
Identities = 24/82 (29%), Positives = 47/82 (57%), Gaps = 6/82 (7%)
Query: 123 RKLEEKQARKAQREAE-EAER--EERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE 179
RKLE Q Q++ + EA+R +E + + ++ +A+ ++ E L ++Q EE+ R+
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ---EEKMWRQ 302
Query: 180 EQAQREHEEYLKLKEAFVVEEE 201
E+ +E EE + +E + E+E
Sbjct: 303 EEKIQEQEEKMCEQELKIREQE 324
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 58.5 bits (140), Expect = 7e-09
Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 25/160 (15%)
Query: 67 RRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEE---GVEKPAETHLSGKIGAKKLR 123
R++ R Q ++R +++ E E++ I QEEE EK E + +KLR
Sbjct: 392 RQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLR 451
Query: 124 KLEEK----------QARKAQREAEEAEREERK------------RLESQREAEWKKEEE 161
++EEK Q K QR+ E+ + +E K ++ Q E W++EE+
Sbjct: 452 EVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEK 511
Query: 162 RLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
EE+ +E+EE+ R+E+ RE E L +E + E+E
Sbjct: 512 MWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 57.4 bits (137), Expect = 2e-08
Identities = 40/144 (27%), Positives = 76/144 (52%), Gaps = 7/144 (4%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEE---EGVEKPAETHLSGKIGAKKLRKLEEKQARKAQ 134
R+ +++ E E+E + QEE E EK E +K+R+ EEK+ K
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 135 REAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKE 194
R+ E+ RE+ +++ Q E W++EE+ LEE +++EE+ E+ +E EE ++ +E
Sbjct: 410 RQ-EKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 195 AFVVEEEGVGETMTEEQSQSFLTE 218
+ +E E + E++ +++ E
Sbjct: 469 EKIQRQE---EKIQEQEEKTWRQE 489
Score = 55.8 bits (133), Expect = 5e-08
Identities = 46/169 (27%), Positives = 85/169 (50%), Gaps = 19/169 (11%)
Query: 53 LEPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQE--EEGVEKPAE 110
L+ E R G + + + ++LQAQ + W ++ +EE + +E +E EK E
Sbjct: 260 LQVEADRLG---KELQSVSAKLQAQVEENEL-WNLLNQQQEEKMWRQEEKIQEQEEKMCE 315
Query: 111 THLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQK 170
L K+R+ EEK R+ EE E+ +++ Q + W++EE+ EE+ +
Sbjct: 316 QEL-------KIREQEEKMWRQ-----EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363
Query: 171 EEEERKAREEQAQREHEEYL-KLKEAFVVEEEGVGETMTEEQSQSFLTE 218
E+EE+ R+E+ RE +E + + +E +EE + E + Q + + E
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Score = 51.6 bits (122), Expect = 9e-07
Identities = 43/174 (24%), Positives = 86/174 (49%), Gaps = 15/174 (8%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREA 137
R+ +++ E E+E I QEE+ + + H +K+R+ E+K R+
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQ----EEKIREQEDKMWRQ----- 351
Query: 138 EEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFV 197
EE RE+ +++ Q E W++EE+ +E+ +E+EE R+E+ RE EE K +E
Sbjct: 352 EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE--KRQEKMW 409
Query: 198 VEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLASQVGLRTQDTINRIQD 251
+E + M E+ + E + ++ K+ LE++ + ++ ++Q+
Sbjct: 410 RQE----KKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQE 459
Score = 48.5 bits (114), Expect = 8e-06
Identities = 40/154 (25%), Positives = 78/154 (50%), Gaps = 18/154 (11%)
Query: 78 RRAQRVAWAEADENEEEAVILAQEEEGV----EKPAETHLSGKIGAKKLRKLEEK---QA 130
R + W + ++ E+ + ++E+ + EK E + +K+ + EEK Q
Sbjct: 321 REQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQD 380
Query: 131 RKAQREAEEAEREE---RKRLESQREAEWKKE------EERLRLEEEQ--KEEEERKARE 179
K Q + EE R+E R++ E ++E W++E +E++R +EE+ ++EE+ + E
Sbjct: 381 EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELE 440
Query: 180 EQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQ 213
E Q + E+ +++E EEE + E + Q Q
Sbjct: 441 EMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Score = 29.3 bits (64), Expect = 4.7
Identities = 24/82 (29%), Positives = 47/82 (57%), Gaps = 6/82 (7%)
Query: 123 RKLEEKQARKAQREAE-EAER--EERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE 179
RKLE Q Q++ + EA+R +E + + ++ +A+ ++ E L ++Q EE+ R+
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQ---EEKMWRQ 302
Query: 180 EQAQREHEEYLKLKEAFVVEEE 201
E+ +E EE + +E + E+E
Sbjct: 303 EEKIQEQEEKMCEQELKIREQE 324
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 6/128 (4%)
Query: 65 RRRRDLGSRLQAQRRAQRVAWAEAD---ENEEEAVILAQEEEGVEKPAETHLSGKIGAKK 121
+R+RD + R +R W + D E E + Q + EK E +IG K
Sbjct: 91 QRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDK 150
Query: 122 LRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQ 181
R++E ++ R +RE E ER + E Q++ E +++ +R E ++++E+ + R+ Q
Sbjct: 151 DREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDR---ERQREKEDRERDRDRQ 207
Query: 182 AQREHEEY 189
+RE + Y
Sbjct: 208 KEREKDRY 215
Score = 41.6 bits (96), Expect = 0.001
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKL 125
R+RD +R+ QR + D E +E E E E + + +K R+
Sbjct: 128 RQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGE--TERYRDRERERQKQRET 185
Query: 126 EEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQ 181
+ R+ QRE E+ ER+ ++ E +++ ++E R R +E +E + K R+ Q
Sbjct: 186 RRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQ 241
Score = 37.4 bits (85), Expect = 0.017
Identities = 25/129 (19%), Positives = 61/129 (47%), Gaps = 10/129 (7%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEAD-ENEEEAVILAQEEEGVEKPAETHLSGKIGA----- 119
R R+ + Q +R QR E D E + + I ++ +E + ++G
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
Query: 120 ----KKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEER 175
++ ++ E ++ R +R+ E+ +RE + + +RE + +E E R +++++ E +
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
Query: 176 KAREEQAQR 184
+ ++ Q+
Sbjct: 234 REKDRDRQK 242
Score = 37.0 bits (84), Expect = 0.023
Identities = 25/116 (21%), Positives = 54/116 (46%), Gaps = 15/116 (12%)
Query: 122 LRKLEEKQARKAQRE-AEEAEREERKRLESQREAEWKKEEERLRLE-------------- 166
+R+ E ++ R+ QR+ A+E RE+ + +E R+ + K++ ER R
Sbjct: 57 IRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDR 116
Query: 167 EEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINY 222
E + E +E + R+ +RE + + + ++++ ET + + + E Y
Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERY 172
Score = 35.0 bits (79), Expect = 0.086
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 79 RAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAE 138
R RVA A E E + + E ++ E H +K R + K+ R+ QR +
Sbjct: 48 RGSRVAPAIIRERERQR----ERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRD 103
Query: 139 EAEREERKRLESQREAEWKKEEERLRLEEEQKEEE-ERKAREE 180
+ ER + RE E +++EER R + ++E++ ER+ + E
Sbjct: 104 RDRKRERWG-DRDRETETERQEERERQRDRKREKDRERQRQRE 145
Score = 35.0 bits (79), Expect = 0.086
Identities = 17/72 (23%), Positives = 39/72 (54%), Gaps = 4/72 (5%)
Query: 117 IGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERK 176
I ++ ++ E+Q ++ A+E RE+ + +E R+ + K++ ER R + ++ E
Sbjct: 57 IRERERQRERERQRKR----AKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWG 112
Query: 177 AREEQAQREHEE 188
R+ + + E +E
Sbjct: 113 DRDRETETERQE 124
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 57.8 bits (138), Expect = 1e-08
Identities = 51/193 (26%), Positives = 77/193 (39%), Gaps = 7/193 (3%)
Query: 23 RSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQR 82
R + R +E +E R ++ G E R+R QR+ +R
Sbjct: 181 REKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTER 240
Query: 83 VAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQA-RKAQREAEEAE 141
E + E ++ E +K E + +K E+Q RK QR E
Sbjct: 241 ER-----EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDR 295
Query: 142 REERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEE 201
ERKR E QRE E ++E R R E ++E E + RE + RE E K K ++ E
Sbjct: 296 ETERKR-ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 202 GVGETMTEEQSQS 214
+T E + Q+
Sbjct: 355 RNRQTGREGRRQA 367
Score = 54.7 bits (130), Expect = 1e-07
Identities = 39/135 (28%), Positives = 67/135 (49%), Gaps = 2/135 (1%)
Query: 54 EPEEPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEAD-ENEEEAVILAQEEEGVEKPAETH 112
E + R R R R+ R + +R +R E D E E E Q E E+ +T
Sbjct: 302 ERQRERERERERNRKRERER-ERERERERQRETERDREKERERKRKRQTEMDRERNRQTG 360
Query: 113 LSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEE 172
G+ A++ R+ E ++ R++ RE EE ER+ + + +RE + +K+ + R E+Q+E
Sbjct: 361 REGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRER 420
Query: 173 EERKAREEQAQREHE 187
E+ + E +R E
Sbjct: 421 EKDRESERGRERGRE 435
Score = 52.4 bits (124), Expect = 5e-07
Identities = 50/193 (25%), Positives = 77/193 (39%), Gaps = 5/193 (2%)
Query: 23 RSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSR---LQAQRR 79
R R R E H+E R + E E R R R R+ R QA+R
Sbjct: 191 RERQREKENKTEDRHSERGRERERERET-ETETERKRQTDRERDRQRKTEREREKQAERE 249
Query: 80 AQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEE 139
E D+ E ++ + +K E K + R E ++ R+ QRE E
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 140 AEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVE 199
ERE ++ E +RE E ++E +R + +KE E ++ R+ + RE + E
Sbjct: 310 -ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE 368
Query: 200 EEGVGETMTEEQS 212
E E + QS
Sbjct: 369 RERERERERDRQS 381
Score = 52.0 bits (123), Expect = 7e-07
Identities = 42/150 (28%), Positives = 73/150 (48%), Gaps = 11/150 (7%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKL 125
R+RD Q R +R + + + + + E+ ET G+ G R+
Sbjct: 89 RKRDRHRERQRDREKERERQTDRERDRQRE---KERNRQKERERETEREGERGRD--RQT 143
Query: 126 EEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQRE 185
+ ++ R+ QR+AE+ ERE + E QR+ E +++ER E +K +ER+ RE Q ++E
Sbjct: 144 DGQRERERQRDAEK-ERERQTDRERQRQTERNRQKER----EREKNRQERRERERQREKE 198
Query: 186 HE-EYLKLKEAFVVEEEGVGETMTEEQSQS 214
++ E + E E ET TE + Q+
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQT 228
Score = 51.2 bits (121), Expect = 1e-06
Identities = 53/205 (25%), Positives = 82/205 (40%), Gaps = 29/205 (14%)
Query: 23 RSRGRAASAGQEPLHNEELAGAGRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQR 82
R R R +E E A E E R R R RR Q R+ QR
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 83 VAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAER 142
E D E + E E+ E + K ++ R+ E ++ R+ +R+ E+
Sbjct: 290 RT--ERDRETER-----KRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
Query: 143 EERKRL-------------ESQREAEWKKEEERLRLEEEQKEEEER-KAREEQAQREHEE 188
+RKR E +R+AE ++E ER R + +E EER + R+ Q+E E
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERER 402
Query: 189 YLKLKEAFVVEEEGVGETMTEEQSQ 213
E++ G+ TE+Q +
Sbjct: 403 Q--------TEKDRDGQRETEKQRE 419
Score = 48.9 bits (115), Expect = 6e-06
Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 9/154 (5%)
Query: 66 RRRDLGSRLQAQRRAQRVAWAEAD-ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRK 124
R RD + R+ +R E + E + Q E ++ AE + ++ R+
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170
Query: 125 LEEKQARKAQREAEEAEREERKRLESQREAEWKKEE---ERLRLEEEQKEEEERKAREEQ 181
E + ++ +RE ER ER+R QRE E K E+ ER R E ++E E R+ Q
Sbjct: 171 TERNRQKEREREKNRQERRERER---QREKENKTEDRHSERGRERERERETETETERKRQ 227
Query: 182 AQREHEEYLKL--KEAFVVEEEGVGETMTEEQSQ 213
RE + K + E E E TE +
Sbjct: 228 TDRERDRQRKTEREREKQAERERASERETERDKE 261
Score = 47.8 bits (112), Expect = 1e-05
Identities = 45/195 (23%), Positives = 75/195 (38%), Gaps = 7/195 (3%)
Query: 23 RSRGRAASAGQEPLHNEELAGA-GRVAQPGPLEPEEPRAGGRPRRRRDLGSRLQAQRRAQ 81
R R + + +E E G GR Q E + R R Q Q
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 82 RVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAE 141
R E ++N +E ++ E K + H ++ R+ E + RK Q + E
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE--- 231
Query: 142 REERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE---EQAQREHEEYLKLKEAFVV 198
R+ +++ E +RE + ++E R E KE E + R+ ++ Q+E E K
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 199 EEEGVGETMTEEQSQ 213
E + E E Q +
Sbjct: 292 ERDRETERKRERQRE 306
Score = 47.4 bits (111), Expect = 2e-05
Identities = 44/153 (28%), Positives = 77/153 (50%), Gaps = 14/153 (9%)
Query: 67 RRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLE 126
RR GS+ +RR A +AD ++ E + E EK + + K+ R+ E
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDR---KRERRRE 84
Query: 127 EKQARKAQREAE-EAEREERKRLESQREAEWKKEEERLRLEEEQKEEEER--KAREEQ-- 181
+ + RK R E + +RE+ + ++ RE + ++E+ER R +E ++E E + R+ Q
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 182 AQREHEEYLKLKEAFVVEEEGVGETMTEEQSQS 214
QRE E + ++A E+E +T E Q Q+
Sbjct: 145 GQRERE---RQRDA---EKERERQTDRERQRQT 171
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 57.4 bits (137), Expect = 2e-08
Identities = 51/188 (27%), Positives = 99/188 (52%), Gaps = 11/188 (5%)
Query: 63 RPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKL 122
+ R+ ++L +AQR+A+R+ E + + L Q EG + AE + +L
Sbjct: 357 KERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMEL 416
Query: 123 RKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQ--KEEEERKAREE 180
+ EE+ AR+ QR E E ++R + Q E + +++EE +R+ + + +EEEE+ +
Sbjct: 417 K--EEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLM 474
Query: 181 QAQREHEEYLK--LKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDL-ASQ 237
Q + E E Y++ +E +++E ++ + +Q+Q L E ++Q++ ED+ A+Q
Sbjct: 475 QLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEE----VRQNRQRADEDVEAAQ 530
Query: 238 VGLRTQDT 245
LR T
Sbjct: 531 RKLRQAST 538
Score = 47.8 bits (112), Expect = 1e-05
Identities = 51/194 (26%), Positives = 91/194 (46%), Gaps = 21/194 (10%)
Query: 59 RAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQ-EEEGVEKPAETHLSGKI 117
+A G+ +DL + + QR + A EEE + L Q +EE K E L +
Sbjct: 314 QAEGKTSLHKDLKQKRREQREQRERRRAA---KEEELLRLQQLQEEKERKLQELELLQEA 370
Query: 118 GAKKLRKLEEKQARKAQREAE-----EAEREERKRLESQREAEWK-KEEERLRLEEEQKE 171
+ R L+E++ R+ + E E + E ++ + +AE + KEEE R + KE
Sbjct: 371 QRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKE 430
Query: 172 EEERKAREEQA------QREHEEYLKLKEAFVV--EEEGVGETMTEEQSQSFLTEFINYI 223
EE + R ++A R EE +++ + ++ EEE + + M ++ Q +I
Sbjct: 431 LEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQE---RYIERA 487
Query: 224 KQSKVVLLEDLASQ 237
+Q K L +++A Q
Sbjct: 488 QQEKEELQQEMAQQ 501
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/75 (36%), Positives = 47/75 (62%), Gaps = 8/75 (10%)
Query: 124 KLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKARE---- 179
+L+ + ++ ++ RE+R++ E +R A KEEE LRL++ Q EE+ERK +E
Sbjct: 312 RLQAEGKTSLHKDLKQKRREQREQRERRRAA---KEEELLRLQQLQ-EEKERKLQELELL 367
Query: 180 EQAQREHEEYLKLKE 194
++AQR+ E L+ +E
Sbjct: 368 QEAQRQAERLLQEEE 382
Score = 40.4 bits (93), Expect = 0.002
Identities = 48/203 (23%), Positives = 90/203 (44%), Gaps = 16/203 (7%)
Query: 105 VEKPAETHLSGKIGAKKLRKLEEKQARKAQREAE------EAEREERKRLESQREAEWKK 158
++ +T L + K+ + E+++ R+A +E E E +ERK E + E ++
Sbjct: 313 LQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQR 372
Query: 159 EEERLRLEEEQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTE 218
+ ERL Q+EEE R+++ + Q+ E +L+EA E +E+ + +
Sbjct: 373 QAERLL----QEEEERRRSQHRELQQALEG--QLREAEQARASMQAEMELKEEEAARQRQ 426
Query: 219 FINYIKQSKVVLLEDLASQVGLRTQDTINRIQDLLAEGTITGVIDDRGKFIYITPEELAA 278
I +++ + L E L +V R + RI A+ + +++ K + EE
Sbjct: 427 RIKELEEMQQRLQEALQLEVKARRDEESVRI----AQTRLLEEEEEKLKQLMQLKEEQER 482
Query: 279 VANFIRQRGRVSIAELAQASNSL 301
+Q E+AQ S SL
Sbjct: 483 YIERAQQEKEELQQEMAQQSRSL 505
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 57.4 bits (137), Expect = 2e-08
Identities = 39/136 (28%), Positives = 76/136 (55%), Gaps = 4/136 (2%)
Query: 120 KKLRKLEEKQARKAQREAEEAER---EERKRLESQR-EAEWKKEEERLRLEEEQKEEEER 175
+KL++LE+++ + +RE E ER EERK+ E + E E K+EE+ + E++Q++ E R
Sbjct: 276 QKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELR 335
Query: 176 KAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSKVVLLEDLA 235
+ +++ + + EE +L+E +EE + QS + E ++ K K+ E
Sbjct: 336 RNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKE 395
Query: 236 SQVGLRTQDTINRIQD 251
++ L+ Q+ R+Q+
Sbjct: 396 EKLRLQQQEERRRLQE 411
Score = 45.1 bits (105), Expect = 8e-05
Identities = 43/206 (20%), Positives = 86/206 (41%), Gaps = 33/206 (16%)
Query: 77 QRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQRE 136
+R+ +R E ++ EE +E E ++ E ++ RK EEK ++ Q++
Sbjct: 270 KRQLERQKLQELEQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQ 329
Query: 137 AEEAEREERKRLESQREAEWKKEEERLRLEE----------------------------- 167
+ R +K+LE + E K+ +E+++LEE
Sbjct: 330 RDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKAVKLR 389
Query: 168 EQKEEEERKAREEQAQREHEEYLKLKEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQSK 227
EQ+++EE+ ++Q +R + +L+ +E +G E + L E + I SK
Sbjct: 390 EQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERE----LRERLLSILLSK 445
Query: 228 VVLLEDLASQVGLRTQDTINRIQDLL 253
++G+ D + + D+L
Sbjct: 446 KPDDSHTHDELGVAHADLLQPVLDIL 471
Score = 39.3 bits (90), Expect = 0.005
Identities = 36/148 (24%), Positives = 65/148 (43%), Gaps = 26/148 (17%)
Query: 57 EPRAGGRPRRRRDLGSRLQAQRRAQRVAWAEADENEEEAVILAQEEEGVEKPAETHLSGK 116
E R R++++L + ++R +++ E + + E ++ E ++ + L K
Sbjct: 296 EERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQEK 355
Query: 117 IGAKKLRKLEEKQARKAQREA-------------------EEAEREERKRLESQREAEWK 157
I KLEE++ AQR E+ ++EE+ RL+ Q E +
Sbjct: 356 I------KLEERKLLLAQRNLQSIRLIAELLSRAKAVKLREQEQKEEKLRLQQQEERR-R 408
Query: 158 KEEERLRLEEEQKEEEERKAREEQAQRE 185
+E LR EE+KE R+E+ RE
Sbjct: 409 LQEAELRRVEEEKERALGLQRKERELRE 436
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 57.4 bits (137), Expect = 2e-08
Identities = 29/70 (41%), Positives = 45/70 (64%), Gaps = 2/70 (2%)
Query: 117 IGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKE--EEE 174
+ + K+ K E+++ RK + E E EER+RL+ + E ++EEERLR EEE++ EEE
Sbjct: 176 VASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEE 235
Query: 175 RKAREEQAQR 184
R E+Q Q+
Sbjct: 236 RLRLEQQKQQ 245
Score = 48.5 bits (114), Expect = 8e-06
Identities = 25/66 (37%), Positives = 40/66 (60%)
Query: 111 THLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQK 170
+H K +K RK EE++ R+ + E E ++EE KR + E ++EEER R+EEE+
Sbjct: 178 SHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERLRREEEERRRIEEERL 237
Query: 171 EEEERK 176
E++K
Sbjct: 238 RLEQQK 243
Score = 46.2 bits (108), Expect = 4e-05
Identities = 29/93 (31%), Positives = 52/93 (55%), Gaps = 5/93 (5%)
Query: 133 AQREAEEAEREERKRLESQREAEWKKEEERLRLEEEQKEEEERKAREEQAQREHEEYLKL 192
A + E+ E+E++++ E +R ++E ERL+ EEE++ EE EE+ +RE EE ++
Sbjct: 177 ASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREE----EERLRREEEERRRI 232
Query: 193 KEAFVVEEEGVGETMTEEQSQSFLTEFINYIKQ 225
+E + E+ + M SQ+ +F Y Q
Sbjct: 233 EEERLRLEQQKQQIMAALNSQT-AVQFQQYAAQ 264
Score = 36.2 bits (82), Expect = 0.039
Identities = 27/82 (32%), Positives = 43/82 (52%), Gaps = 18/82 (21%)
Query: 90 ENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERKRLE 149
E EE+ +EEE + E ++L+K EEK+ R+ + E E EER+R+
Sbjct: 182 EKEEQEKKRKEEEERRRREEEER-------ERLQKEEEKR-RREEEERLRREEEERRRI- 232
Query: 150 SQREAEWKKEEERLRLEEEQKE 171
EEERLRLE+++++
Sbjct: 233 ---------EEERLRLEQQKQQ 245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,953,442
Number of Sequences: 37866
Number of extensions: 652010
Number of successful extensions: 35366
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1044
Number of HSP's successfully gapped in prelim test: 1024
Number of HSP's that attempted gapping in prelim test: 7378
Number of HSP's gapped (non-prelim): 11320
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.