Search of human proteins with 4505047

Search of human proteins with 4505047

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505047 lumican precursor [Homo sapiens]
         (338 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505047 lumican precursor [Homo sapiens]                           683   0.0  
gi|71040111 fibromodulin precursor [Homo sapiens]                     310   2e-84
gi|41349454 proline arginine-rich end leucine-rich repeat protei...   238   7e-63
gi|4506041 proline arginine-rich end leucine-rich repeat protein...   238   7e-63
gi|4826876 osteomodulin [Homo sapiens]                                236   2e-62
gi|5901992 keratocan [Homo sapiens]                                   236   2e-62
gi|41350214 asporin [Homo sapiens]                                    147   1e-35
gi|19743846 decorin isoform a preproprotein [Homo sapiens]            137   1e-32
gi|4503271 decorin isoform a preproprotein [Homo sapiens]             137   1e-32
gi|4502403 biglycan preproprotein [Homo sapiens]                      128   6e-30
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]                  124   2e-28
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]                  124   2e-28
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]    123   2e-28
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]                  107   1e-23
gi|45505137 podocan [Homo sapiens]                                    105   6e-23
gi|153251229 chondroadherin precursor [Homo sapiens]                  105   6e-23
gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa...    99   4e-21
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho...    99   4e-21
gi|156139147 leucine rich repeat transmembrane neuronal 4 isofor...    98   1e-20
gi|197927168 leucine rich repeat transmembrane neuronal 4 isofor...    98   1e-20
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom...    98   1e-20
gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo s...    96   5e-20
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...    96   6e-20
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...    96   6e-20
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ...    94   2e-19
gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo sapi...    92   9e-19
gi|198041768 synleurin [Homo sapiens]                                  90   3e-18
gi|7661704 osteoglycin preproprotein [Homo sapiens]                    87   3e-17
gi|14916498 osteoglycin preproprotein [Homo sapiens]                   87   3e-17
gi|4504379 leucine-rich repeat-containing G protein-coupled rece...    86   5e-17

>gi|4505047 lumican precursor [Homo sapiens]
          Length = 338

 Score =  683 bits (1762), Expect = 0.0
 Identities = 338/338 (100%), Positives = 338/338 (100%)

Query: 1   MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
           MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS
Sbjct: 1   MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60

Query: 61  VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKK 120
           VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKK
Sbjct: 61  VPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKK 120

Query: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180
           LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF
Sbjct: 121 LHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAF 180

Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
           KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE
Sbjct: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240

Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGP 300
           LADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGP
Sbjct: 241 LADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGP 300

Query: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338
           LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN
Sbjct: 301 LSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN 338


>gi|71040111 fibromodulin precursor [Homo sapiens]
          Length = 376

 Score =  310 bits (793), Expect = 2e-84
 Identities = 148/318 (46%), Positives = 221/318 (69%), Gaps = 8/318 (2%)

Query: 26  PLSIYGQSSP----NCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHI 81
           P   YG  SP    +C  EC+CP ++P+AMYCD   LK +P VP  +KY+Y +NNQI  I
Sbjct: 61  PAYTYGSPSPPDPRDCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSI 120

Query: 82  DEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLED 141
            E  F+N T L W+ L  N + + K+  +VFSKL+ L++L+++HNNLT   GPLP+SL +
Sbjct: 121 QEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRE 180

Query: 142 LQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARL 199
           L L HN+I+++   + EGL NLT ++LQHN ++E  V ++ +GL+SL  LDLS+N + ++
Sbjct: 181 LHLDHNQISRVPNNALEGLENLTALYLQHNEIQE--VGSSMRGLRSLILLDLSYNHLRKV 238

Query: 200 PSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVEL 259
           P GLP +L  LY+++N +  +PD YF+    L Y+RLSHN L ++G+  N+FN SSL+EL
Sbjct: 239 PDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLEL 298

Query: 260 DLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISET 319
           DLSYN+L+ IP VN NLEN YL+ N++ +F I SFC ++  +++SK++ LRLDGN I  +
Sbjct: 299 DLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSFCTVVDVVNFSKLQVLRLDGNEIKRS 358

Query: 320 SLPPDMYECLRVANEVTL 337
           ++P D   CLR+A+ + +
Sbjct: 359 AMPADAPLCLRLASLIEI 376


>gi|41349454 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  238 bits (606), Expect = 7e-63
 Identities = 127/315 (40%), Positives = 193/315 (61%), Gaps = 15/315 (4%)

Query: 35  PNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQW 94
           P+C  EC CP  +PSA+YCD   L+ VP++PP I YLYL+NN I  +  ++F+N T L+W
Sbjct: 71  PDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRW 130

Query: 95  LILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL-- 152
           + LD+N +   KI  RV  KL  L  L++  N L E    LP++LE L+L+ N I+++  
Sbjct: 131 INLDNNRIR--KIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPP 188

Query: 153 GSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLY 211
           G F  L NL  + LQHNRL +       F GLK+L  L+L+ N + ++P  +P ++  LY
Sbjct: 189 GVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLY 248

Query: 212 LDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPT 271
           LD+NKI  IP+ YFK F  L ++RL++N+L D G+P NSFN+S+L+ L LS+N++ ++P 
Sbjct: 249 LDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPA 308

Query: 272 VNENLENYYLEVNQLEKF--------DIKSFCKILGPL-SYSKIKHLRLDGNRISETSLP 322
           +N  LE+ YL  N +EK         D+ +F      L +   +++LRLDGN + +  +P
Sbjct: 309 INNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYL-KPPIP 367

Query: 323 PDMYECLRVANEVTL 337
            D+  C R+   V +
Sbjct: 368 LDLMMCFRLLQSVVI 382


>gi|4506041 proline arginine-rich end leucine-rich repeat protein
           precursor [Homo sapiens]
          Length = 382

 Score =  238 bits (606), Expect = 7e-63
 Identities = 127/315 (40%), Positives = 193/315 (61%), Gaps = 15/315 (4%)

Query: 35  PNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQW 94
           P+C  EC CP  +PSA+YCD   L+ VP++PP I YLYL+NN I  +  ++F+N T L+W
Sbjct: 71  PDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRW 130

Query: 95  LILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL-- 152
           + LD+N +   KI  RV  KL  L  L++  N L E    LP++LE L+L+ N I+++  
Sbjct: 131 INLDNNRIR--KIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPP 188

Query: 153 GSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLY 211
           G F  L NL  + LQHNRL +       F GLK+L  L+L+ N + ++P  +P ++  LY
Sbjct: 189 GVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLY 248

Query: 212 LDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPT 271
           LD+NKI  IP+ YFK F  L ++RL++N+L D G+P NSFN+S+L+ L LS+N++ ++P 
Sbjct: 249 LDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPA 308

Query: 272 VNENLENYYLEVNQLEKF--------DIKSFCKILGPL-SYSKIKHLRLDGNRISETSLP 322
           +N  LE+ YL  N +EK         D+ +F      L +   +++LRLDGN + +  +P
Sbjct: 309 INNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYL-KPPIP 367

Query: 323 PDMYECLRVANEVTL 337
            D+  C R+   V +
Sbjct: 368 LDLMMCFRLLQSVVI 382


>gi|4826876 osteomodulin [Homo sapiens]
          Length = 421

 Score =  236 bits (603), Expect = 2e-62
 Identities = 127/303 (41%), Positives = 191/303 (63%), Gaps = 8/303 (2%)

Query: 19  QYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQI 78
           Q  DY  P   + Q +  C  EC CP ++PS+MYCD  KLK++P +P  I+ LYL+ N+I
Sbjct: 47  QNVDYGVP---FHQYTLGCVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEI 103

Query: 79  DHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKS 138
           + +   +F N T L+ + L HN +++ KI   VF+KL  L +LH+ HNNL E   PLPKS
Sbjct: 104 EAVTANSFINATHLKEINLSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKS 163

Query: 139 LEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQ 195
           LE L L +N+I+KL   + +GLVNLT + L +N L +  +    F  ++ L  L+L  N+
Sbjct: 164 LERLLLGYNEISKLQTNAMDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNR 223

Query: 196 IARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSS 255
           +  +P GLP SL+ L L+NN IS+IP++YF +   L  LR+SHN+L D  IP N FN+ +
Sbjct: 224 LESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPN 281

Query: 256 LVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNR 315
           +VEL + +NKLK    +  NLE+ YL+ N++EK ++   C  + PL Y  + ++R+D N+
Sbjct: 282 IVELSVGHNKLKQAFYIPRNLEHLYLQNNEIEKMNLTVMCPSIDPLHYHHLTYIRVDQNK 341

Query: 316 ISE 318
           + E
Sbjct: 342 LKE 344



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 44/187 (23%), Positives = 85/187 (45%), Gaps = 41/187 (21%)

Query: 57  KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
           +L+S+P  +P  + YL L NN I  I EK F+ +  L  L + HN L++  I   +F+ L
Sbjct: 223 RLESMPPGLPSSLMYLSLENNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFN-L 279

Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDA 175
             + +L + HN L ++   +P++LE L                      +LQ+N +++  
Sbjct: 280 PNIVELSVGHNKLKQAFY-IPRNLEHL----------------------YLQNNEIEKMN 316

Query: 176 VSAAFKGLKSLEYLDLSFNQIARLPSGLPVS---------LLTLYLDNNKISN-----IP 221
           ++     +  L Y  L++ ++ +     P+S         + T+Y    + +N     + 
Sbjct: 317 LTVMCPSIDPLHYHHLTYIRVDQNKLKEPISSYIFFCFPHIHTIYYGEQRSTNGQTIQLK 376

Query: 222 DEYFKRF 228
            + F+RF
Sbjct: 377 TQVFRRF 383


>gi|5901992 keratocan [Homo sapiens]
          Length = 352

 Score =  236 bits (602), Expect = 2e-62
 Identities = 123/312 (39%), Positives = 194/312 (62%), Gaps = 12/312 (3%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLI 96
           C  EC CP S+P+A+YC+   LK +P +P  I YLYL+NN I+ I EK FEN T L+W+ 
Sbjct: 42  CPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWIN 101

Query: 97  LDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GS 154
           L+ N + N  I+    S+LK+L  L +  N L E   PLP+SLE LQL  NK++++  G+
Sbjct: 102 LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGT 161

Query: 155 FEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLD 213
           F  L NLT + LQ+N+L ++A     FKGLK+L  L+++ N +  +P  LP + + L+LD
Sbjct: 162 FSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLD 221

Query: 214 NNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVN 273
           NN I  IP+ YF     + +LRL+HN+L+D G+P   F+VSS+++L LS+N+L  +P ++
Sbjct: 222 NNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRIS 281

Query: 274 ENLENYYLEVNQLEKFDIKSFCKILGPL-----SYS---KIKHLRLDGNRISETSLPPDM 325
            +L++ +L+ N+++  ++   C     L     S+S    +++LRLDGN I +  +P  +
Sbjct: 282 AHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEI-KPPIPMAL 340

Query: 326 YECLRVANEVTL 337
             C R+   V +
Sbjct: 341 MTCFRLLQAVII 352


>gi|41350214 asporin [Homo sapiens]
          Length = 380

 Score =  147 bits (371), Expect = 1e-35
 Identities = 99/312 (31%), Positives = 169/312 (54%), Gaps = 18/312 (5%)

Query: 25  FPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDE 83
           FP  ++    P C   C C   Y   ++C +L L SVP  +P   + L L+NN+I  I E
Sbjct: 67  FPFDLF----PMCPFGCQC---YSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKE 119

Query: 84  KAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQ 143
             F+ +T L  LIL++N L  +KI  + F   K+L++L+++HN L+E    LPKSL +L+
Sbjct: 120 NDFKGLTSLYGLILNNNKL--TKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELR 177

Query: 144 LTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLP 200
           +  NK+ K+   +F+G+  L  + +  N L  + +   AF+G+ ++ ++ ++  ++  +P
Sbjct: 178 IHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVP 236

Query: 201 SGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELD 260
            GLP +LL L+LD NKIS +  E FKR+  LQ L L +N++ D    G+  N+  + E+ 
Sbjct: 237 KGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIE-NGSLANIPRVREIH 295

Query: 261 LSYNKLKNIPT---VNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRIS 317
           L  NKLK IP+     + L+  +L  N + +  +  FC  +  +  S    + L  N + 
Sbjct: 296 LENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVK 355

Query: 318 ETSLPPDMYECL 329
              + P  + C+
Sbjct: 356 YWEMQPATFRCV 367


>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  137 bits (345), Expect = 1e-32
 Identities = 101/323 (31%), Positives = 159/323 (49%), Gaps = 17/323 (5%)

Query: 22  DYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDH 80
           D DF  S+     P C   C C   +   + C +L L  VP  +PP    L L+NN+I  
Sbjct: 43  DRDFEPSL----GPVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITE 95

Query: 81  IDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLE 140
           I +  F+N+ +L  LIL +N +  SK+    F+ L +L++L+++ N L E    +PK+L+
Sbjct: 96  IKDGDFKNLKNLHALILVNNKI--SKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQ 153

Query: 141 DLQLTHNKITKLG--SFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIA 197
           +L+   N+ITK+   +F GL  +  I L  N LK   + + AF+G+K L Y+ ++   I 
Sbjct: 154 ELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNIT 213

Query: 198 RLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLV 257
            +P GLP SL  L+LD NKIS +     K  N L  L LS N ++ +   G+  N   L 
Sbjct: 214 SIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS-AVDNGSLANTPHLR 272

Query: 258 ELDLSYNKLKNIP---TVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGN 314
           EL L  NKL  +P     ++ ++  YL  N +       FC        +    + L  N
Sbjct: 273 ELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSN 332

Query: 315 RISETSLPPDMYECLRVANEVTL 337
            +    + P  + C+ V + + L
Sbjct: 333 PVQYWEIQPSTFRCVYVRSAIQL 355


>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
          Length = 359

 Score =  137 bits (345), Expect = 1e-32
 Identities = 101/323 (31%), Positives = 159/323 (49%), Gaps = 17/323 (5%)

Query: 22  DYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDH 80
           D DF  S+     P C   C C   +   + C +L L  VP  +PP    L L+NN+I  
Sbjct: 43  DRDFEPSL----GPVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITE 95

Query: 81  IDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLE 140
           I +  F+N+ +L  LIL +N +  SK+    F+ L +L++L+++ N L E    +PK+L+
Sbjct: 96  IKDGDFKNLKNLHALILVNNKI--SKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQ 153

Query: 141 DLQLTHNKITKLG--SFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQIA 197
           +L+   N+ITK+   +F GL  +  I L  N LK   + + AF+G+K L Y+ ++   I 
Sbjct: 154 ELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNIT 213

Query: 198 RLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLV 257
            +P GLP SL  L+LD NKIS +     K  N L  L LS N ++ +   G+  N   L 
Sbjct: 214 SIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSIS-AVDNGSLANTPHLR 272

Query: 258 ELDLSYNKLKNIP---TVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGN 314
           EL L  NKL  +P     ++ ++  YL  N +       FC        +    + L  N
Sbjct: 273 ELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSN 332

Query: 315 RISETSLPPDMYECLRVANEVTL 337
            +    + P  + C+ V + + L
Sbjct: 333 PVQYWEIQPSTFRCVYVRSAIQL 355


>gi|4502403 biglycan preproprotein [Homo sapiens]
          Length = 368

 Score =  128 bits (322), Expect = 6e-30
 Identities = 101/311 (32%), Positives = 157/311 (50%), Gaps = 14/311 (4%)

Query: 26  PLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEK 84
           P S+    S  C   C+C   +   + C +L LKSVP  + P    L L+NN I  + + 
Sbjct: 52  PDSVTPTYSAMCPFGCHC---HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKD 108

Query: 85  AFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQL 144
            F+ +  L  L+L +N +  SKI  + FS L++L+KL+I+ N+L E    LP SL +L++
Sbjct: 109 DFKGLQHLYALVLVNNKI--SKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRI 166

Query: 145 THNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPS 201
             N+I K+  G F GL N+  I +  N L+       AF GLK L YL +S  ++  +P 
Sbjct: 167 HDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPK 225

Query: 202 GLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDL 261
            LP +L  L+LD+NKI  I  E   R++ L  L L HN++        SF + +L EL L
Sbjct: 226 DLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHL 284

Query: 262 SYNKLKNIPTVNEN---LENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISE 318
             NKL  +P+   +   L+  YL  N + K  +  FC +   +  +    + L  N +  
Sbjct: 285 DNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPY 344

Query: 319 TSLPPDMYECL 329
             + P  + C+
Sbjct: 345 WEVQPATFRCV 355


>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
          Length = 510

 Score =  124 bits (310), Expect = 2e-28
 Identities = 90/300 (30%), Positives = 150/300 (50%), Gaps = 14/300 (4%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVP-MVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
           C   C+CP      + CD L L+  P  +    ++L L+NNQ+  +       ++ L+ L
Sbjct: 44  CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101

Query: 96  ILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG-- 153
            L +NL+ +  +    F  L QL+ L + HN L+ +   LP+SL    L  N++ ++   
Sbjct: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPL 161

Query: 154 SFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
           +F     L  ++L +N+L    +   AF+G +++  L LS NQ++ LP  LP SL  L+L
Sbjct: 162 TFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHL 221

Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN-VSSLVELDLSYNKLKNIPT 271
            NN IS +P     R   L+ L L HN+L DSG+   +F+ + SL  LDLS+N+L  +P 
Sbjct: 222 QNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 281

Query: 272 -VNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLR 330
            +   L   +L  N++ + +        G      +++L L  N++  + LP      LR
Sbjct: 282 GLPRTLAILHLGRNRIRQVEAARLHGARG------LRYLLLQHNQLGSSGLPAGALRPLR 335



 Score =  108 bits (270), Expect = 7e-24
 Identities = 81/274 (29%), Positives = 132/274 (48%), Gaps = 11/274 (4%)

Query: 62  PMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKL 121
           P +PP ++ L+L+NN I  +   A    T L+ L L HN L +S +    FSKL  L+ L
Sbjct: 210 PSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 269

Query: 122 HINHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSA- 178
            ++HN LT     LP++L  L L  N+I ++      G   L ++ LQHN+L    + A 
Sbjct: 270 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 329

Query: 179 AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSH 238
           A + L+ L  L L  N + R+P  LP  L  L L +N ++ +          L  L L++
Sbjct: 330 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 389

Query: 239 NELADSGIPGNSF-NVSSLVELDLSYNKLKNIPT-VNENLENYYLEVNQLEKFDIKSFCK 296
           N LA + +   +F  + +L  LDL+ N+L  +P  +   L    L+ NQL   + +    
Sbjct: 390 NRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAG 449

Query: 297 ILGPLSYSKIKHLRLDGNRISETSLPPDMYECLR 330
           +       +++ L L  NR+    + P  +  L+
Sbjct: 450 L------DQLRELSLAHNRLRVGDIGPGTWHELQ 477



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 57  KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
           +L  +PM +P G++ L L+ NQ+  ++ +    +  L+ L L HN L    I    +   
Sbjct: 417 QLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTW--- 473

Query: 116 KQLKKLHINHNNLTESVGPLPKS 138
            +L+ L + H  ++ +V   P S
Sbjct: 474 HELQALQVRHRLVSHTVPRAPPS 496


>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
          Length = 512

 Score =  124 bits (310), Expect = 2e-28
 Identities = 90/300 (30%), Positives = 150/300 (50%), Gaps = 14/300 (4%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVP-MVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
           C   C+CP      + CD L L+  P  +    ++L L+NNQ+  +       ++ L+ L
Sbjct: 46  CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 103

Query: 96  ILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG-- 153
            L +NL+ +  +    F  L QL+ L + HN L+ +   LP+SL    L  N++ ++   
Sbjct: 104 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPL 163

Query: 154 SFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
           +F     L  ++L +N+L    +   AF+G +++  L LS NQ++ LP  LP SL  L+L
Sbjct: 164 TFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHL 223

Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN-VSSLVELDLSYNKLKNIPT 271
            NN IS +P     R   L+ L L HN+L DSG+   +F+ + SL  LDLS+N+L  +P 
Sbjct: 224 QNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 283

Query: 272 -VNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLR 330
            +   L   +L  N++ + +        G      +++L L  N++  + LP      LR
Sbjct: 284 GLPRTLAILHLGRNRIRQVEAARLHGARG------LRYLLLQHNQLGSSGLPAGALRPLR 337



 Score =  108 bits (270), Expect = 7e-24
 Identities = 81/274 (29%), Positives = 132/274 (48%), Gaps = 11/274 (4%)

Query: 62  PMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKL 121
           P +PP ++ L+L+NN I  +   A    T L+ L L HN L +S +    FSKL  L+ L
Sbjct: 212 PSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 271

Query: 122 HINHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSA- 178
            ++HN LT     LP++L  L L  N+I ++      G   L ++ LQHN+L    + A 
Sbjct: 272 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 331

Query: 179 AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSH 238
           A + L+ L  L L  N + R+P  LP  L  L L +N ++ +          L  L L++
Sbjct: 332 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 391

Query: 239 NELADSGIPGNSF-NVSSLVELDLSYNKLKNIPT-VNENLENYYLEVNQLEKFDIKSFCK 296
           N LA + +   +F  + +L  LDL+ N+L  +P  +   L    L+ NQL   + +    
Sbjct: 392 NRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAG 451

Query: 297 ILGPLSYSKIKHLRLDGNRISETSLPPDMYECLR 330
           +       +++ L L  NR+    + P  +  L+
Sbjct: 452 L------DQLRELSLAHNRLRVGDIGPGTWHELQ 479



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 57  KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
           +L  +PM +P G++ L L+ NQ+  ++ +    +  L+ L L HN L    I    +   
Sbjct: 419 QLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTW--- 475

Query: 116 KQLKKLHINHNNLTESVGPLPKS 138
            +L+ L + H  ++ +V   P S
Sbjct: 476 HELQALQVRHRLVSHTVPRAPPS 498


>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
          Length = 699

 Score =  123 bits (309), Expect = 2e-28
 Identities = 84/251 (33%), Positives = 136/251 (54%), Gaps = 5/251 (1%)

Query: 43  CPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLL 102
           C  SY +    + +  +  P+  P I  L L  N I  I ++AF  + +L+ L L  N +
Sbjct: 320 CSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNNI 379

Query: 103 ENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG--SFEGLVN 160
            +S I  + F  LK+L +L+++ NNL +    LP +LE+L++  N +  +   S   L  
Sbjct: 380 TSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQ 439

Query: 161 LTFIHLQHNRLKEDAVS-AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISN 219
           L  + L+ N L E  V+  AFK LKSL YL L  N+   +P GLP S+  LYL+NN+I  
Sbjct: 440 LVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEE 499

Query: 220 IPDEYFKRFNALQYLRLSHNELADSGI-PGNSFNVSSLVELDLSYNKLKNIPT-VNENLE 277
           I +  F     +  + L +N++ ++ I P    N  +L  +DLSYNKL ++P+ + ++L 
Sbjct: 500 ITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLL 559

Query: 278 NYYLEVNQLEK 288
           +  L  NQ+E+
Sbjct: 560 HLVLLGNQIER 570



 Score =  116 bits (290), Expect = 3e-26
 Identities = 88/283 (31%), Positives = 146/283 (51%), Gaps = 10/283 (3%)

Query: 64  VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHI 123
           +P  ++ L +  N +  IDE++  ++  L  L L+ N L  + +    F  LK L  L +
Sbjct: 412 LPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRL 471

Query: 124 NHNNLTESVGPLPKSLEDLQLTHNKITKLGS--FEGLVNLTFIHLQHNRLKEDAVSA-AF 180
             N        LP S+E+L L +N+I ++    F     +  I L++N+++E+ ++  A+
Sbjct: 472 GKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAW 531

Query: 181 KGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFN-ALQYLRLSHN 239
              ++LE +DLS+N++  +PS LP SLL L L  N+I  IP   F      L+YL LS N
Sbjct: 532 INQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFN 591

Query: 240 ELADSGIPGNSFNVS--SLVELDLSYNKLKNIPT-VNENLENYYLEVNQLEKFDI--KSF 294
           +LAD G+   SF  +  SL EL L +N LK+IP  + E    ++L +N  +  +I  +  
Sbjct: 592 KLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEI 651

Query: 295 CKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTL 337
           C        S ++HL L+ N I    +P   + C+R  + + L
Sbjct: 652 CNAEED-DDSNLEHLHLENNYIKIREIPSYTFSCIRSYSSIVL 693



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 61/209 (29%), Positives = 105/209 (50%), Gaps = 13/209 (6%)

Query: 57  KLKSVPMVPPG-IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
           K + +P   PG I+ LYL NNQI+ I E  F +   +  ++L +N +E ++I    +   
Sbjct: 475 KFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQ 534

Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSF---EGLVNLTFIHLQHNRLK 172
           + L+ + +++N L      LPKSL  L L  N+I ++  +        L +++L  N+L 
Sbjct: 535 ENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFGHMEPGLEYLYLSFNKLA 594

Query: 173 EDAVS--AAFKGLKSLEYLDLSFNQIARLPSGLP--VSLLTLYLDNNKISNI-PDEYFKR 227
           +D +   + +    SL  L L  N +  +P G+    +L  L L+NNKI NI P+E    
Sbjct: 595 DDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLRLNNNKIRNILPEEICNA 654

Query: 228 ----FNALQYLRLSHNELADSGIPGNSFN 252
                + L++L L +N +    IP  +F+
Sbjct: 655 EEDDDSNLEHLHLENNYIKIREIPSYTFS 683



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 29/156 (18%)

Query: 198 RLPSGLPVS---------------------LLTLYLDNNKISNIPDEYFKRFNALQYLRL 236
           RLPSG  +S                     + +L L  N I++IPDE F     L+ L L
Sbjct: 315 RLPSGCSLSYRTISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDL 374

Query: 237 SHNELADSGIPGNSFN-VSSLVELDLSYNKLKNIPT-VNENLENYYLEVNQLEKFDIKSF 294
           S N +  SGI   +F  +  L+ L++  N L  IP+ +   LE   +  N L+  D +S 
Sbjct: 375 SKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESL 434

Query: 295 CKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLR 330
             +      +++  L L+GN +SE ++ P  ++ L+
Sbjct: 435 SDL------NQLVTLELEGNNLSEANVNPLAFKPLK 464


>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
          Length = 421

 Score =  107 bits (268), Expect = 1e-23
 Identities = 74/239 (30%), Positives = 114/239 (47%), Gaps = 25/239 (10%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVP-MVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
           C   C+CP      + CD L L+  P  +    ++L L+NNQ+  +       ++ L+ L
Sbjct: 44  CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101

Query: 96  ILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--G 153
            L +NL+ +  +    F  L QL+ L + HN                   +N I+K+  G
Sbjct: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRG 143

Query: 154 SFEGLVNLTFIHLQHNRLKEDAVSAA-FKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYL 212
           +      L  ++LQHN+L +  + A  F  L SLEYLDLS NQ+  +P+GLP +L  L+L
Sbjct: 144 ALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHL 203

Query: 213 DNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN-VSSLVELDLSYNKLKNIP 270
             N+I  +          L+YL L HN+L  SG+P  +   +  L  L L  N L  +P
Sbjct: 204 GRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVP 262



 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 68/205 (33%), Positives = 104/205 (50%), Gaps = 5/205 (2%)

Query: 57  KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
           +L +VP  +P  +  L+L  N+I  ++         L++L+L HN L +S +       L
Sbjct: 186 QLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPL 245

Query: 116 KQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVN--LTFIHLQHNRLKE 173
           + L  LH+  N L      LP+ L  L L HN +  LG+ + +    LT ++L +NRL  
Sbjct: 246 RGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLAS 305

Query: 174 DAVS-AAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQ 232
             V   AF+ L++L  LDL+ NQ+ RLP GLP  L TL L  N++  +  E     + L+
Sbjct: 306 ARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLR 365

Query: 233 YLRLSHNELADSGI-PGNSFNVSSL 256
            L L+HN L    I PG    + +L
Sbjct: 366 ELSLAHNRLRVGDIGPGTWHELQAL 390



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 4/83 (4%)

Query: 57  KLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKL 115
           +L  +PM +P G++ L L+ NQ+  ++ +    +  L+ L L HN L    I    +   
Sbjct: 328 QLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTW--- 384

Query: 116 KQLKKLHINHNNLTESVGPLPKS 138
            +L+ L + H  ++ +V   P S
Sbjct: 385 HELQALQVRHRLVSHTVPRAPPS 407


>gi|45505137 podocan [Homo sapiens]
          Length = 661

 Score =  105 bits (262), Expect = 6e-23
 Identities = 98/385 (25%), Positives = 171/385 (44%), Gaps = 85/385 (22%)

Query: 31  GQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHI-------- 81
           G ++ +C  +C C  S    + C  + L+  P  +P    +L L+NNQ++ I        
Sbjct: 110 GPAAVSCPRDCAC--SQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRL 167

Query: 82  ------------------DEKAFENVTDLQWLILDHNLLENS------------------ 105
                              EKAFE++T+L +L L +N L  +                  
Sbjct: 168 HRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYL 227

Query: 106 -KIKGRVFSKLKQLKKLHINHNNLTESVGP--------------------------LPKS 138
            KI G  F +   L+ +++++N L ++  P                          LP +
Sbjct: 228 TKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPA 287

Query: 139 LEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLDLSFNQ 195
           L  L L +NK+ K+  G+F  L +L  ++LQ+N L ++ + +  F  L SLEYLDLS N 
Sbjct: 288 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNN 347

Query: 196 IARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSF-NVS 254
           ++R+P+GLP SL+ L+L+ N I ++         +L+YL L  N+L + GI   +F  + 
Sbjct: 348 LSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLK 407

Query: 255 SLVELDLSYNKLKNIPT-VNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDG 313
            L  + L  N L+ +P+ +   +    +  NQ+     + F       +   ++ L L  
Sbjct: 408 RLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFA------TTYFLEELNLSY 461

Query: 314 NRISETSLPPDMYECLRVANEVTLN 338
           NRI+   +  D +  LR+   + L+
Sbjct: 462 NRITSPQVHRDAFRKLRLLRSLDLS 486



 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 67/212 (31%), Positives = 112/212 (52%), Gaps = 5/212 (2%)

Query: 58  LKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLK 116
           L+ VP  +P  ++ L + +NQI  I  + F     L+ L L +N + + ++    F KL+
Sbjct: 419 LERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLR 478

Query: 117 QLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKED 174
            L+ L ++ N L      LP+++  L++  N++  L  G+  G+  L  ++L  NRL+  
Sbjct: 479 LLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSR 538

Query: 175 AVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQY 233
           A+   A+  L  L+ LD++ NQ+  +P GLP SL  LYL NNKIS +P   F     L+ 
Sbjct: 539 ALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKG 598

Query: 234 LRLSHNELADSGIPGNSF-NVSSLVELDLSYN 264
           + L  N+LA   +  ++F  +  L  LD+  N
Sbjct: 599 IFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630


>gi|153251229 chondroadherin precursor [Homo sapiens]
          Length = 359

 Score =  105 bits (262), Expect = 6e-23
 Identities = 86/307 (28%), Positives = 143/307 (46%), Gaps = 40/307 (13%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLI 96
           C   C+C       + CD++ L+ +P V    K L L+ N    +   +F  + +L  L 
Sbjct: 23  CPQNCHCHSDLQHVI-CDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLH 81

Query: 97  LDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLED---LQLTHNKITKL- 152
           L H  +   ++    F  LKQL  L+++HN++          L +   L L HNK+T+L 
Sbjct: 82  LQHCQIR--EVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELP 139

Query: 153 -GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGL---PVSLL 208
            G    LVNL  + L +N+++E   + AF+G K L +L LS N ++ L  G      +L 
Sbjct: 140 RGLLSPLVNLFILQLNNNKIRE-LRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLA 198

Query: 209 TLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKN 268
             ++D N++S+ P     +   ++ L+LSHN L    IP N+F                 
Sbjct: 199 KFHVDRNQLSSYPSAALSKLRVVEELKLSHNPL--KSIPDNAFQ---------------- 240

Query: 269 IPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISE--TSLPPDMY 326
             +    LE  +L+   LEKF   +F      L  + +KH+ L+ NR+++  ++ P D  
Sbjct: 241 --SFGRYLETLWLDNTNLEKFSDGAF------LGVTTLKHVHLENNRLNQLPSNFPFDSL 292

Query: 327 ECLRVAN 333
           E L + N
Sbjct: 293 ETLALTN 299



 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 67/207 (32%), Positives = 103/207 (49%), Gaps = 15/207 (7%)

Query: 70  YLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLT 129
           YLYL +N I  +   AF+++T+L +L LDHN +  +++   + S L  L  L +N+N + 
Sbjct: 103 YLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKV--TELPRGLLSPLVNLFILQLNNNKIR 160

Query: 130 E-SVGPL--PKSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLK 184
           E   G     K L  L L+ N ++ L  G+ + + NL   H+  N+L     SAA   L+
Sbjct: 161 ELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAKFHVDRNQL-SSYPSAALSKLR 219

Query: 185 SLEYLDLSFNQIARLPSGLPVS----LLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNE 240
            +E L LS N +  +P     S    L TL+LDN  +    D  F     L+++ L +N 
Sbjct: 220 VVEELKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEKFSDGAFLGVTTLKHVHLENNR 279

Query: 241 LADSGIPGNSFNVSSLVELDLSYNKLK 267
           L  + +P N F   SL  L L+ N  K
Sbjct: 280 L--NQLPSN-FPFDSLETLALTNNPWK 303


>gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo
           sapiens]
          Length = 516

 Score = 99.4 bits (246), Expect = 4e-21
 Identities = 87/270 (32%), Positives = 140/270 (51%), Gaps = 22/270 (8%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVP-MVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
           C P+C C +      YCD     SVP     G   L LR+N I  ++   F + + L WL
Sbjct: 34  CPPKCRCEKLL---FYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWL 90

Query: 96  ILDHNLLENSKIKGRVFSKLKQLKKLHINHNN---LTESVGPLPKSLEDLQLTHNKITKL 152
            LDHN +  S +K   F  L +LK+L ++ N    L  +      +L++L L+ N+++ L
Sbjct: 91  HLDHNQI--STVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSL 148

Query: 153 GS--FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLP----SGLPVS 206
               F GL  L  +HL+ N L+   V   F   +SLE+LDLS N++  L     +GL + 
Sbjct: 149 HPELFYGLRKLQTLHLRSNSLRTIPV-RLFWDCRSLEFLDLSTNRLRSLARNGFAGL-IK 206

Query: 207 LLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKL 266
           L  L+L++N+++ I   +F R ++L  L L  N++++    G  +   +L +LDL+ N++
Sbjct: 207 LRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTC-GMEWTWGTLEKLDLTGNEI 265

Query: 267 KNIP-TVNE---NLENYYLEVNQLEKFDIK 292
           K I  TV E   NL+   ++ N+L   D K
Sbjct: 266 KAIDLTVFETMPNLKILLMDNNKLNSLDSK 295


>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
           sapiens]
          Length = 674

 Score = 99.4 bits (246), Expect = 4e-21
 Identities = 88/305 (28%), Positives = 145/305 (47%), Gaps = 47/305 (15%)

Query: 34  SPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDL 92
           S  C   C C   +   +YC++  L S+P  +P     LYL+NNQI++            
Sbjct: 51  STTCPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQNNQINNA----------- 96

Query: 93  QWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL 152
                   + ++ K K  V       + +++  N+L E    LP+SL +L L  N +  +
Sbjct: 97  -------GIPQDLKTKVNV-------QVIYLYENDLDEFPINLPRSLRELHLQDNNVRTI 142

Query: 153 G--SFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLT 209
              S   +  L  +HL  N +   ++   AF   K L+ L LS N ++ +PSGLP +L  
Sbjct: 143 ARDSLARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEE 202

Query: 210 LYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN-VSSLVELDLSYNKLK- 267
           L LD+N+IS IP   FK  N+L+ L L  N LA+  I  ++F+ + +L EL L  N L  
Sbjct: 203 LRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAA 262

Query: 268 ---NIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPD 324
              N+P+   +L+  YL+ N +      +  K+       +++ L L  N +  T+LP  
Sbjct: 263 PPLNLPSA--HLQKLYLQDNAISHIPYNTLAKM------RELERLDLSNNNL--TTLPRG 312

Query: 325 MYECL 329
           +++ L
Sbjct: 313 LFDDL 317


>gi|156139147 leucine rich repeat transmembrane neuronal 4 isoform b
           [Homo sapiens]
          Length = 518

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 80/264 (30%), Positives = 131/264 (49%), Gaps = 22/264 (8%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
           C   C C       +YC+      +P  +  G + L LR N I  +    F  +  L WL
Sbjct: 34  CPKNCRCDGKI---VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWL 90

Query: 96  ILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLT----ESVGPLPKSLEDLQLTHNKITK 151
            LDHN +  S +    F  +++LK+L ++ N +T    ++  P+P +L +L L++NK+  
Sbjct: 91  YLDHNYI--SSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVP-NLRNLDLSYNKLQT 147

Query: 152 LGS--FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLL- 208
           L S  F+GL  L  +HL+ N LK   +   F+  ++L++LDL +N++  L       LL 
Sbjct: 148 LQSEQFKGLRKLIILHLRSNSLKTVPI-RVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLK 206

Query: 209 --TLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKL 266
              L+L++N+ S I   +F R   L+ + L  N +  S   G ++  SSL  LDLS N +
Sbjct: 207 LKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR-SISQGLTWTWSSLHNLDLSGNDI 265

Query: 267 KNIPTVN----ENLENYYLEVNQL 286
           + I         NL+   L+ N+L
Sbjct: 266 QGIEPGTFKCLPNLQKLNLDSNKL 289



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 35/204 (17%)

Query: 68  IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
           +K L L +N+I ++  K F  V +L+ L L +N L+   ++   F  L++L  LH+  N+
Sbjct: 111 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQT--LQSEQFKGLRKLIILHLRSNS 168

Query: 128 LTE---SVGPLPKSLEDLQLTHNKITKLG--SFEGLVNLTFIHLQHNR------------ 170
           L      V    ++L+ L L +N++  L   +F GL+ L  +HL+HN+            
Sbjct: 169 LKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRL 228

Query: 171 -------LKEDAVSAAFKGL----KSLEYLDLSFNQIARLPSG----LPVSLLTLYLDNN 215
                  L+ + + +  +GL     SL  LDLS N I  +  G    LP +L  L LD+N
Sbjct: 229 FNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLP-NLQKLNLDSN 287

Query: 216 KISNIPDEYFKRFNALQYLRLSHN 239
           K++NI  E    + +L  + LS N
Sbjct: 288 KLTNISQETVNAWISLISITLSGN 311



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 16/134 (11%)

Query: 189 LDLSFNQIARLPS----GLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADS 244
           L L FN I +L S    GL   L+ LYLD+N IS++ ++ F+    L+ L LS N++  +
Sbjct: 66  LSLRFNSIQKLKSNQFAGLN-QLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKI--T 122

Query: 245 GIPGNSFN-VSSLVELDLSYNKLKNIPTVN----ENLENYYLEVNQLEKFDIKSF--CKI 297
            +   +F+ V +L  LDLSYNKL+ + +        L   +L  N L+   I+ F  C+ 
Sbjct: 123 YLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 182

Query: 298 LG--PLSYSKIKHL 309
           L    L Y++++ L
Sbjct: 183 LDFLDLGYNRLRSL 196


>gi|197927168 leucine rich repeat transmembrane neuronal 4 isoform a
           [Homo sapiens]
          Length = 590

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 80/264 (30%), Positives = 131/264 (49%), Gaps = 22/264 (8%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWL 95
           C   C C       +YC+      +P  +  G + L LR N I  +    F  +  L WL
Sbjct: 34  CPKNCRCDGKI---VYCESHAFADIPENISGGSQGLSLRFNSIQKLKSNQFAGLNQLIWL 90

Query: 96  ILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLT----ESVGPLPKSLEDLQLTHNKITK 151
            LDHN +  S +    F  +++LK+L ++ N +T    ++  P+P +L +L L++NK+  
Sbjct: 91  YLDHNYI--SSVDEDAFQGIRRLKELILSSNKITYLHNKTFHPVP-NLRNLDLSYNKLQT 147

Query: 152 LGS--FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLL- 208
           L S  F+GL  L  +HL+ N LK   +   F+  ++L++LDL +N++  L       LL 
Sbjct: 148 LQSEQFKGLRKLIILHLRSNSLKTVPI-RVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLK 206

Query: 209 --TLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKL 266
              L+L++N+ S I   +F R   L+ + L  N +  S   G ++  SSL  LDLS N +
Sbjct: 207 LKELHLEHNQFSKINFAHFPRLFNLRSIYLQWNRIR-SISQGLTWTWSSLHNLDLSGNDI 265

Query: 267 KNIPTVN----ENLENYYLEVNQL 286
           + I         NL+   L+ N+L
Sbjct: 266 QGIEPGTFKCLPNLQKLNLDSNKL 289



 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 35/204 (17%)

Query: 68  IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
           +K L L +N+I ++  K F  V +L+ L L +N L+   ++   F  L++L  LH+  N+
Sbjct: 111 LKELILSSNKITYLHNKTFHPVPNLRNLDLSYNKLQT--LQSEQFKGLRKLIILHLRSNS 168

Query: 128 LTE---SVGPLPKSLEDLQLTHNKITKLG--SFEGLVNLTFIHLQHNR------------ 170
           L      V    ++L+ L L +N++  L   +F GL+ L  +HL+HN+            
Sbjct: 169 LKTVPIRVFQDCRNLDFLDLGYNRLRSLSRNAFAGLLKLKELHLEHNQFSKINFAHFPRL 228

Query: 171 -------LKEDAVSAAFKGL----KSLEYLDLSFNQIARLPSG----LPVSLLTLYLDNN 215
                  L+ + + +  +GL     SL  LDLS N I  +  G    LP +L  L LD+N
Sbjct: 229 FNLRSIYLQWNRIRSISQGLTWTWSSLHNLDLSGNDIQGIEPGTFKCLP-NLQKLNLDSN 287

Query: 216 KISNIPDEYFKRFNALQYLRLSHN 239
           K++NI  E    + +L  + LS N
Sbjct: 288 KLTNISQETVNAWISLISITLSGN 311



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 45/134 (33%), Positives = 72/134 (53%), Gaps = 16/134 (11%)

Query: 189 LDLSFNQIARLPS----GLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADS 244
           L L FN I +L S    GL   L+ LYLD+N IS++ ++ F+    L+ L LS N++  +
Sbjct: 66  LSLRFNSIQKLKSNQFAGLN-QLIWLYLDHNYISSVDEDAFQGIRRLKELILSSNKI--T 122

Query: 245 GIPGNSFN-VSSLVELDLSYNKLKNIPTVN----ENLENYYLEVNQLEKFDIKSF--CKI 297
            +   +F+ V +L  LDLSYNKL+ + +        L   +L  N L+   I+ F  C+ 
Sbjct: 123 YLHNKTFHPVPNLRNLDLSYNKLQTLQSEQFKGLRKLIILHLRSNSLKTVPIRVFQDCRN 182

Query: 298 LG--PLSYSKIKHL 309
           L    L Y++++ L
Sbjct: 183 LDFLDLGYNRLRSL 196


>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
           sapiens]
          Length = 660

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 87/300 (29%), Positives = 141/300 (47%), Gaps = 45/300 (15%)

Query: 27  LSIYGQSSP--NCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDE 83
           L +Y Q S    C   C C  ++   +YC+E  L SVP+ +P G+  LYL NNQI++   
Sbjct: 24  LGLYSQVSKLLACPSVCRCDRNF---VYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGF 80

Query: 84  KA-FENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNL-TESVGPLPK--SL 139
            A   NV  +  + L  N L+   +     +  K ++ LH+  NN+ T S   L +   L
Sbjct: 81  PAELHNVQSVHTVYLYGNQLDEFPM-----NLPKNVRVLHLQENNIQTISRAALAQLLKL 135

Query: 140 EDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARL 199
           E+L L  N I+ +G  +G                     AF+   SL+ L LS N ++ +
Sbjct: 136 EELHLDDNSISTVGVEDG---------------------AFREAISLKLLFLSKNHLSSV 174

Query: 200 PSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSF-NVSSLVE 258
           P GLPV L  L +D N+I+ I D  F+   +L+ L +  N L + GI   +F +++ L E
Sbjct: 175 PVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKE 234

Query: 259 LDLSYNKLKNIP--TVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRI 316
             +  N L + P      +L   YL+ NQ+    + +F  +       K++ L +  N++
Sbjct: 235 FSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNL------RKLERLDISNNQL 288



 Score = 65.1 bits (157), Expect = 9e-11
 Identities = 52/154 (33%), Positives = 80/154 (51%), Gaps = 23/154 (14%)

Query: 51  MYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKG 109
           ++  +  L SVP+ +P  ++ L +  N+I  I + AF+N+T L+ LI+D NLL N  I  
Sbjct: 164 LFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAE 223

Query: 110 RVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHN 169
             FS L +LK+  I  N+L+    P P    DL  TH              L  ++LQ N
Sbjct: 224 GTFSHLTKLKEFSIVRNSLSH---PPP----DLPGTH--------------LIRLYLQDN 262

Query: 170 RLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGL 203
           ++    ++A F  L+ LE LD+S NQ+  L  G+
Sbjct: 263 QINHIPLTA-FSNLRKLERLDISNNQLRMLTQGV 295


>gi|86990456 leucine rich repeat transmembrane neuronal 1 [Homo
           sapiens]
          Length = 522

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 80/265 (30%), Positives = 140/265 (52%), Gaps = 26/265 (9%)

Query: 37  CAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLI 96
           C   C C       +YC+ L L   P    G+  L LR N +  +    F  +  L WL 
Sbjct: 39  CPQLCRCEGRL---LYCEALNLTEAPHNLSGLLGLSLRYNSLSELRAGQFTGLMQLTWLY 95

Query: 97  LDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTE----SVGPLPKSLEDLQLTHNKITKL 152
           LDHN +    ++G  F KL+++K+L ++ N +T+    +  P+P +L  + L++NK+  L
Sbjct: 96  LDHNHI--CSVQGDAFQKLRRVKELTLSSNQITQLPNTTFRPMP-NLRSVDLSYNKLQAL 152

Query: 153 GS--FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLP----SGLPVS 206
               F GL  LT +H++ N ++   V   F+  +SL++LD+ +NQ+  L     +GL   
Sbjct: 153 APDLFHGLRKLTTLHMRANAIQFVPV-RIFQDCRSLKFLDIGYNQLKSLARNSFAGL-FK 210

Query: 207 LLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN-VSSLVELDLSYNK 265
           L  L+L++N +  +   +F R  +L  L L  N++A   I  +S + V +L ++DLS N+
Sbjct: 211 LTELHLEHNDLVKVNFAHFPRLISLHSLCLRRNKVA---IVVSSLDWVWNLEKMDLSGNE 267

Query: 266 LKNI-PTVNE---NLENYYLEVNQL 286
           ++ + P V E   +L++  L+ N+L
Sbjct: 268 IEYMEPHVFETVPHLQSLQLDSNRL 292


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 95/340 (27%), Positives = 164/340 (48%), Gaps = 57/340 (16%)

Query: 1   MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
           M  +A+++FL  IG   G +     PLS+  +S P+    C C   +   +YC++  L S
Sbjct: 1   MISAAWSIFL--IGTKIGLFLQVA-PLSVMAKSCPSV---CRCDAGF---IYCNDRFLTS 51

Query: 61  VPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLK 119
           +P  +P     LYL+NNQI+                        N+ I   + + LK ++
Sbjct: 52  IPTGIPEDATTLYLQNNQIN------------------------NAGIPSDLKNLLK-VE 86

Query: 120 KLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSA- 178
           ++++ HN+L E    LPK +++L L  N I  + +++ L  + ++   H  L +++VSA 
Sbjct: 87  RIYLYHNSLDEFPTNLPKYVKELHLQENNIRTI-TYDSLSKIPYLEELH--LDDNSVSAV 143

Query: 179 -----AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQY 233
                AF+    L  L LS N ++ +P GLP ++  L LD+N+IS I     +   +L+ 
Sbjct: 144 SIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKR 203

Query: 234 LRLSHNELADSGIPGN-SFNVSSLVELDLSYNKLKNIPT--VNENLENYYLEVNQLEKFD 290
           L L  N L + G+     FN+ +L EL L  N L   P      NL   YL+ N + +  
Sbjct: 204 LVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINR-- 261

Query: 291 IKSFCKILGPLSYSKIKHL-RLDGNRISETSLPPDMYECL 329
                  + P ++S ++ L RLD +  + ++LP  +++ L
Sbjct: 262 -------VPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 8/178 (4%)

Query: 162 TFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIP 221
           T ++LQ+N++    + +  K L  +E + L  N +   P+ LP  +  L+L  N I  I 
Sbjct: 61  TTLYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTIT 120

Query: 222 DEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVE-LDLSYNKLKNIP-TVNENLENY 279
            +   +   L+ L L  N ++   I   +F  S+ +  L LS N L  IP  +   +E  
Sbjct: 121 YDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEEL 180

Query: 280 YLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTL 337
            L+ N++      S          + +K L LDGN ++   L   ++  L    E++L
Sbjct: 181 RLDDNRISTISSPSL------QGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSL 232


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 95.5 bits (236), Expect = 6e-20
 Identities = 95/340 (27%), Positives = 164/340 (48%), Gaps = 57/340 (16%)

Query: 1   MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKS 60
           M  +A+++FL  IG   G +     PLS+  +S P+    C C   +   +YC++  L S
Sbjct: 1   MISAAWSIFL--IGTKIGLFLQVA-PLSVMAKSCPSV---CRCDAGF---IYCNDRFLTS 51

Query: 61  VPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLK 119
           +P  +P     LYL+NNQI+                        N+ I   + + LK ++
Sbjct: 52  IPTGIPEDATTLYLQNNQIN------------------------NAGIPSDLKNLLK-VE 86

Query: 120 KLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSA- 178
           ++++ HN+L E    LPK +++L L  N I  + +++ L  + ++   H  L +++VSA 
Sbjct: 87  RIYLYHNSLDEFPTNLPKYVKELHLQENNIRTI-TYDSLSKIPYLEELH--LDDNSVSAV 143

Query: 179 -----AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQY 233
                AF+    L  L LS N ++ +P GLP ++  L LD+N+IS I     +   +L+ 
Sbjct: 144 SIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKR 203

Query: 234 LRLSHNELADSGIPGN-SFNVSSLVELDLSYNKLKNIPT--VNENLENYYLEVNQLEKFD 290
           L L  N L + G+     FN+ +L EL L  N L   P      NL   YL+ N + +  
Sbjct: 204 LVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINR-- 261

Query: 291 IKSFCKILGPLSYSKIKHL-RLDGNRISETSLPPDMYECL 329
                  + P ++S ++ L RLD +  + ++LP  +++ L
Sbjct: 262 -------VPPNAFSYLRQLYRLDMSNNNLSNLPQGIFDDL 294



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 8/178 (4%)

Query: 162 TFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIP 221
           T ++LQ+N++    + +  K L  +E + L  N +   P+ LP  +  L+L  N I  I 
Sbjct: 61  TTLYLQNNQINNAGIPSDLKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTIT 120

Query: 222 DEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVE-LDLSYNKLKNIP-TVNENLENY 279
            +   +   L+ L L  N ++   I   +F  S+ +  L LS N L  IP  +   +E  
Sbjct: 121 YDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEEL 180

Query: 280 YLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTL 337
            L+ N++      S          + +K L LDGN ++   L   ++  L    E++L
Sbjct: 181 RLDDNRISTISSPSL------QGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSL 232


>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
           sapiens]
          Length = 581

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 82/274 (29%), Positives = 125/274 (45%), Gaps = 41/274 (14%)

Query: 27  LSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKA 85
           L++   +   C   C C       +YC+  KL+ +P  +  G   L LR N +  +    
Sbjct: 24  LTMLSSAERGCPKGCRCEGKM---VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQ 80

Query: 86  FENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN----LTESVGPLPKSLED 141
           F+ +  L WL LDHN + N  I    F+ +++LK+L ++ N     L  +  P+  +L +
Sbjct: 81  FKGLNQLTWLYLDHNHISN--IDENAFNGIRRLKELILSSNRISYFLNNTFRPVT-NLRN 137

Query: 142 LQLTHNKITKLGS--FEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARL 199
           L L++N++  LGS  F GL  L  +HL+ N L+   V   F+  ++LE LDL +N+I  L
Sbjct: 138 LDLSYNQLHSLGSEQFRGLRKLLSLHLRSNSLRTIPVRI-FQDCRNLELLDLGYNRIRSL 196

Query: 200 PSGL---------------------------PVSLLTLYLDNNKISNIPDEYFKRFNALQ 232
              +                            VSL  LYL  NKIS I       +++LQ
Sbjct: 197 ARNVFAGMIRLKELHLEHNQFSKLNLALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQ 256

Query: 233 YLRLSHNELADSGIPGNSFNVSSLVELDLSYNKL 266
            L LS NE+     P     V +L  L+L  NKL
Sbjct: 257 RLDLSGNEIEAFSGPSVFQCVPNLQRLNLDSNKL 290



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 52/160 (32%), Positives = 79/160 (49%), Gaps = 22/160 (13%)

Query: 164 IHLQHNRLKE--DAVSAAFKGLKSLEYLDLS---FNQIARLPSGLPVSLLTLYLDNNKIS 218
           ++ +  +L+E   ++SA   GL SL Y  L    +NQ   L       L  LYLD+N IS
Sbjct: 45  VYCESQKLQEIPSSISAGCLGL-SLRYNSLQKLKYNQFKGLNQ-----LTWLYLDHNHIS 98

Query: 219 NIPDEYFKRFNALQYLRLSHNELADSGIPGNSFN-VSSLVELDLSYNKLKNIPTVN---- 273
           NI +  F     L+ L LS N +  S    N+F  V++L  LDLSYN+L ++ +      
Sbjct: 99  NIDENAFNGIRRLKELILSSNRI--SYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGL 156

Query: 274 ENLENYYLEVNQLEKFDIKSF--CKILG--PLSYSKIKHL 309
             L + +L  N L    ++ F  C+ L    L Y++I+ L
Sbjct: 157 RKLLSLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSL 196


>gi|68800360 dermatan sulfate proteoglycan 3 precursor [Homo
           sapiens]
          Length = 322

 Score = 91.7 bits (226), Expect = 9e-19
 Identities = 71/244 (29%), Positives = 115/244 (47%), Gaps = 32/244 (13%)

Query: 12  LIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYL 71
           LI G+S Q  ++     + G  +    P C       + +YCD+ +L ++P +P    Y 
Sbjct: 92  LIDGSSPQEPEFT---GVLGPHTNEDFPTCLLCTCISTTVYCDDHELDAIPPLPKNTAYF 148

Query: 72  YLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTES 131
           Y R N+I  I++  F +++DL+ + L  NL+  S+I    F KL QL++L +  N +   
Sbjct: 149 YSRFNRIKKINKNDFASLSDLKRIDLTSNLI--SEIDEDAFRKLPQLRELVLRDNKI--- 203

Query: 132 VGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAV-SAAFKGLKSLEYLD 190
                + L +L  T               LTFI + +NRL    +   AFK +  L +L 
Sbjct: 204 -----RQLPELPTT---------------LTFIDISNNRLGRKGIKQEAFKDMYDLHHLY 243

Query: 191 LSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNS 250
           L+ N +  +P  LP +L  L+L NN I  + ++ F     L Y+R     L D  + GN 
Sbjct: 244 LTDNNLDHIPLPLPENLRALHLQNNNILEMHEDTFCNVKNLTYIR---KALEDIRLDGNP 300

Query: 251 FNVS 254
            N+S
Sbjct: 301 INLS 304


>gi|198041768 synleurin [Homo sapiens]
          Length = 622

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 86/289 (29%), Positives = 145/289 (50%), Gaps = 27/289 (9%)

Query: 53  CDELKLKSVPM-VPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDH-NLLENSKIKGR 110
           C  L L S+P   P    +LYL  N I +I+E     +  L  L LD+ N+L    +  +
Sbjct: 46  CRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILY---VYPK 102

Query: 111 VFSKLKQLKKLHINHNNLTESVGPLPK---SLEDLQLTHNKITKL--GSFEGLVNLTFIH 165
            F +L+ L  L +N+N +      + K   +L +L L +N+++ +  G F  LV++ +++
Sbjct: 103 AFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLN 162

Query: 166 LQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLP-SGLP--VSLLTLYLDNNKISNIPD 222
           LQ NRL     S  F G+ +L  LDLS N I R+  SG     +L  LYL +N ++ +P 
Sbjct: 163 LQRNRLTVLG-SGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPS 221

Query: 223 EYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVN----ENLEN 278
             F+   +L+ L LSHN + ++  P     +++L  L L  ++++N+         NL++
Sbjct: 222 NAFEVLKSLRRLSLSHNPI-EAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLKH 280

Query: 279 YYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYE 327
             L  N LE  +  +F  +        + +L+LD NRI   S+  D +E
Sbjct: 281 LILSHNDLENLNSDTFSLL------KNLIYLKLDRNRI--ISIDNDTFE 321



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 34/106 (32%), Positives = 55/106 (51%), Gaps = 6/106 (5%)

Query: 68  IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNN 127
           ++YL L+N++I ++    F  + +L+ LIL HN LEN  +    FS LK L  L ++ N 
Sbjct: 254 LEYLLLKNSRIRNVTRDGFSGINNLKHLILSHNDLEN--LNSDTFSLLKNLIYLKLDRNR 311

Query: 128 L----TESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHN 169
           +     ++   +  SL+ L L+ N +T L         + IHLQ N
Sbjct: 312 IISIDNDTFENMGASLKILNLSFNNLTALHPRVLKPLSSLIHLQAN 357


>gi|7661704 osteoglycin preproprotein [Homo sapiens]
          Length = 298

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 62/210 (29%), Positives = 100/210 (47%), Gaps = 26/210 (12%)

Query: 39  PECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILD 98
           P C        ++YC+E+ + +VP +P    YLY R N+I  +  K F ++ +L+ L   
Sbjct: 92  PTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFT 151

Query: 99  HNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGL 158
            NL+E+  I+   FSKL  L++L +  N L +     PK                     
Sbjct: 152 GNLIED--IEDGTFSKLSLLEELSLAENQLLKLPVLPPK--------------------- 188

Query: 159 VNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKI 217
             LT  + ++N++K   + A AFK L +L +L L  N +  +P  LP SL  ++L  N I
Sbjct: 189 --LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNI 246

Query: 218 SNIPDEYFKRFNALQYLRLSHNELADSGIP 247
           ++I D+ F + N   Y+R    E+   G P
Sbjct: 247 ASITDDTFCKANDTSYIRDRIEEIRLEGNP 276


>gi|14916498 osteoglycin preproprotein [Homo sapiens]
          Length = 298

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 62/210 (29%), Positives = 100/210 (47%), Gaps = 26/210 (12%)

Query: 39  PECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILD 98
           P C        ++YC+E+ + +VP +P    YLY R N+I  +  K F ++ +L+ L   
Sbjct: 92  PTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADIPNLRRLDFT 151

Query: 99  HNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGL 158
            NL+E+  I+   FSKL  L++L +  N L +     PK                     
Sbjct: 152 GNLIED--IEDGTFSKLSLLEELSLAENQLLKLPVLPPK--------------------- 188

Query: 159 VNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKI 217
             LT  + ++N++K   + A AFK L +L +L L  N +  +P  LP SL  ++L  N I
Sbjct: 189 --LTLFNAKYNKIKSRGIKANAFKKLNNLTFLYLDHNALESVPLNLPESLRVIHLQFNNI 246

Query: 218 SNIPDEYFKRFNALQYLRLSHNELADSGIP 247
           ++I D+ F + N   Y+R    E+   G P
Sbjct: 247 ASITDDTFCKANDTSYIRDRIEEIRLEGNP 276


>gi|4504379 leucine-rich repeat-containing G protein-coupled
           receptor 5 [Homo sapiens]
          Length = 907

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 92/338 (27%), Positives = 150/338 (44%), Gaps = 73/338 (21%)

Query: 44  PESYPSAMYCDELKL--KSVPMVPPG-------IKYLYLRNNQIDHIDEKAFENVTDLQW 94
           P   PS  + +EL+L   ++  +P G       +K L L+NNQ+ H+  +A +N+  LQ 
Sbjct: 83  PNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQS 142

Query: 95  LILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQ---LTHNKITK 151
           L LD N +  S +    FS L  L+ L ++ N LTE      +SL  LQ   L  NKI  
Sbjct: 143 LRLDANHI--SYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHH 200

Query: 152 LG--SFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPV---- 205
           +   +F  L +L  +HL +NR+        F GL SLE LDL++N +   P+ +      
Sbjct: 201 IPDYAFGNLSSLVVLHLHNNRI-HSLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNL 259

Query: 206 ----------------------SLLTLYLDNNKISNIPDEYFKRFNALQYLRLSH----N 239
                                 SL+T++  +N I  +    F+    L+ L L+      
Sbjct: 260 KELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQIT 319

Query: 240 ELAD-----------------SGIPGNSFN-VSSLVELDLSYNKLKNIP--TVNENLENY 279
           E  D                 S +P    N + +L  LDLSYN L+++P  +V + L+  
Sbjct: 320 EFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKI 379

Query: 280 YLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRIS 317
            L  N++ +  + +F ++L       ++ L L  N+I+
Sbjct: 380 DLRHNEIYEIKVDTFQQLL------SLRSLNLAWNKIA 411



 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 64/183 (34%), Positives = 107/183 (58%), Gaps = 18/183 (9%)

Query: 121 LHINHNNLTESV-GPLP--KSLEDLQLTHNKITKL--GSFEGLVNLTFIHLQHNRLKEDA 175
           L ++ NN+++ +  PLP  + LE+L+L  N +T +  G+F GL +L  + LQ+N+L+   
Sbjct: 71  LDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRH-V 129

Query: 176 VSAAFKGLKSLEYLDLSFNQIARLP----SGLPVSLLTLYLDNNKISNIPDEYFKRFNAL 231
            + A + L+SL+ L L  N I+ +P    SGL  SL  L+LD+N ++ IP + F+  +AL
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCFSGLH-SLRHLWLDDNALTEIPVQAFRSLSAL 188

Query: 232 QYLRLSHNELADSGIPGNSF-NVSSLVELDLSYNKLKNIPTV----NENLENYYLEVNQL 286
           Q + L+ N++    IP  +F N+SSLV L L  N++ ++         +LE   L  N L
Sbjct: 189 QAMTLALNKI--HHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNL 246

Query: 287 EKF 289
           ++F
Sbjct: 247 DEF 249



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 79/298 (26%), Positives = 133/298 (44%), Gaps = 28/298 (9%)

Query: 49  SAMYCDELKLKSVPMVPP-------GIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNL 101
           SA+    L L  +  +P         +  L+L NN+I  + +K F+ +  L+ L L++N 
Sbjct: 186 SALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNN 245

Query: 102 LENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLG--SFEGLV 159
           L+      R  S LK+L     N  ++ E       SL  +    N I  +G  +F+ L 
Sbjct: 246 LDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFVGRSAFQHLP 305

Query: 160 NLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLP----SGLPVSLLTLYLDNN 215
            L  + L  N   +        G  +LE L L+  QI+ LP    + LP +L  L L  N
Sbjct: 306 ELRTLTL--NGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLP-NLQVLDLSYN 362

Query: 216 KISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSF-NVSSLVELDLSYNKLKNIPTVNE 274
            + ++P   F     LQ + L HNE+ +  I  ++F  + SL  L+L++NK+  I     
Sbjct: 363 LLEDLPS--FSVCQKLQKIDLRHNEIYE--IKVDTFQQLLSLRSLNLAWNKIAIIH---- 414

Query: 275 NLENYYLEVNQLEKFDIKSFCKILGPLS-YSKIKHLRLDGNRISETSLPPDMYECLRV 331
              N +  +  L K D+ S      P++    + HL+L GN   ++ +  + +  L+V
Sbjct: 415 --PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGNHALQSLISSENFPELKV 470



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 43/154 (27%), Positives = 69/154 (44%), Gaps = 15/154 (9%)

Query: 189 LDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPG 248
           +D S   ++ LPS L V    L L  N IS +          L+ LRL+ N L  + IP 
Sbjct: 50  VDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLEELRLAGNAL--TYIPK 107

Query: 249 NSF-NVSSLVELDLSYNKLKNIPTVN----ENLENYYLEVNQLEKFDIKSFCKILGPLSY 303
            +F  + SL  L L  N+L+++PT       +L++  L+ N +       F  +      
Sbjct: 108 GAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGL------ 161

Query: 304 SKIKHLRLDGNRISETSLPPDMYECLRVANEVTL 337
             ++HL LD N ++E  +P   +  L     +TL
Sbjct: 162 HSLRHLWLDDNALTE--IPVQAFRSLSALQAMTL 193



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 14/134 (10%)

Query: 188 YLDLSFNQIAR-LPSGLPV--SLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADS 244
           YLDLS N I++ LP+ LP    L  L L  N ++ IP   F    +L+ L L +N+L   
Sbjct: 70  YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRH- 128

Query: 245 GIPGNSF-NVSSLVELDLSYNKLKNIP----TVNENLENYYLEVNQLEKFDIKSFCKILG 299
            +P  +  N+ SL  L L  N +  +P    +   +L + +L+ N L +  +++F  +  
Sbjct: 129 -VPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSA 187

Query: 300 ----PLSYSKIKHL 309
                L+ +KI H+
Sbjct: 188 LQAMTLALNKIHHI 201


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.137    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,650,000
Number of Sequences: 37866
Number of extensions: 553260
Number of successful extensions: 3943
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 172
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 1687
Number of HSP's gapped (non-prelim): 913
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.