Search of human proteins with 4504077

Search of human proteins with 4504077

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504077 glycoprotein IX (platelet) precursor [Homo sapiens]
         (177 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504077 glycoprotein IX (platelet) precursor [Homo sapiens]        375   e-105
gi|4504073 glycoprotein Ib, beta polypeptide precursor [Homo sap...    94   6e-20
gi|84781739 leucine-rich repeats and transmembrane domains 2 [Ho...    63   2e-10
gi|188528675 slit homolog 1 [Homo sapiens]                             57   8e-09
gi|11321571 slit homolog 3 [Homo sapiens]                              55   2e-08
gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]    54   5e-08
gi|194306623 immunoglobulin superfamily containing leucine-rich ...    54   9e-08
gi|194306621 immunoglobulin superfamily containing leucine-rich ...    54   9e-08
gi|39930401 immunoglobulin superfamily containing leucine-rich r...    54   9e-08
gi|194306618 immunoglobulin superfamily containing leucine-rich ...    54   9e-08
gi|4759146 slit homolog 2 [Homo sapiens]                               52   2e-07
gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]           52   2e-07
gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]           52   2e-07
gi|40217825 slit and trk like 6 [Homo sapiens]                         52   3e-07
gi|54607118 leucine-rich repeats and immunoglobulin-like domains...    52   4e-07
gi|122937309 leucine rich repeat containing 4B [Homo sapiens]          52   4e-07
gi|239752702 PREDICTED: leucine rich repeat containing 38, parti...    51   5e-07
gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo ...    51   5e-07
gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo ...    51   5e-07
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]       51   6e-07
gi|61966761 leucine rich repeat containing 26 [Homo sapiens]           50   1e-06
gi|194272183 G protein-coupled receptor 124 [Homo sapiens]             50   1e-06
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho...    50   1e-06
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom...    49   2e-06
gi|21281681 leucine-rich repeat LGI family, member 3 [Homo sapiens]    49   3e-06
gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]                 49   3e-06
gi|52353306 leucine rich repeat containing 55 [Homo sapiens]           49   3e-06
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s...    48   4e-06
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa...    48   4e-06
gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens]    48   4e-06

>gi|4504077 glycoprotein IX (platelet) precursor [Homo sapiens]
          Length = 177

 Score =  375 bits (964), Expect = e-105
 Identities = 177/177 (100%), Positives = 177/177 (100%)

Query: 1   MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN 60
           MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN
Sbjct: 1   MPAWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPALPARTRHLLLAN 60

Query: 61  NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA 120
           NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA
Sbjct: 61  NSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCASPSLAA 120

Query: 121 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD 177
           HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD
Sbjct: 121 HGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLLCATTEALD 177


>gi|4504073 glycoprotein Ib, beta polypeptide precursor [Homo
           sapiens]
          Length = 206

 Score = 94.0 bits (232), Expect = 6e-20
 Identities = 63/167 (37%), Positives = 80/167 (47%), Gaps = 16/167 (9%)

Query: 7   LFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLT--ALP-ALPARTRHLLLANNSL 63
           L LL   +     CP+PC+C      G  VDC   GLT  +LP A P  T  L+L  N+L
Sbjct: 13  LLLLAPPSRPAAGCPAPCSCA-----GTLVDCGRRGLTWASLPTAFPVDTTELVLTGNNL 67

Query: 64  QSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEA-LLQVRCASPSLAAHG 122
            ++PPG  D LP L+T  +  NPW CDC L  LR WL  R   A    +RC +P      
Sbjct: 68  TALPPGLLDALPALRTAHLGANPWRCDCRLVPLRAWLAGRPERAPYRDLRCVAPPALR-- 125

Query: 123 PLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLAGLL 169
             GRL  Y       +L+A+     + W      +A LGL LL  LL
Sbjct: 126 --GRLLPYLAED---ELRAACAPGPLCWGALAAQLALLGLGLLHALL 167


>gi|84781739 leucine-rich repeats and transmembrane domains 2 [Homo
           sapiens]
          Length = 370

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 35/84 (41%), Positives = 47/84 (55%), Gaps = 4/84 (4%)

Query: 3   AWGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLANN 61
           +W   ++     EA   CP  C C   ++  L VDC G GLT +P  +PA TR LLL NN
Sbjct: 22  SWITCWIALYAVEALPTCPFSCKC---DSRSLEVDCSGLGLTTVPPDVPAATRTLLLLNN 78

Query: 62  SLQSVPPGAFDHLPQLQTLDVTQN 85
            L ++P  AF +L  LQ LD++ N
Sbjct: 79  KLSALPSWAFANLSSLQRLDLSNN 102



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 21/48 (43%), Positives = 28/48 (58%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLE 101
           R L L +N LQ++    F+ L  LQ L V  NPW CDC+L   + W+E
Sbjct: 167 RSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLREFKHWME 214


>gi|188528675 slit homolog 1 [Homo sapiens]
          Length = 1534

 Score = 57.0 bits (136), Expect = 8e-09
 Identities = 30/67 (44%), Positives = 43/67 (64%), Gaps = 6/67 (8%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLANNSLQSVPPGAFDHLPQLQ 78
           CP+ CTC    + G+ VDCRG GLTA+PA LP     + L  N ++S+PPGAF    +L+
Sbjct: 282 CPAMCTC----SNGI-VDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPYRKLR 336

Query: 79  TLDVTQN 85
            +D++ N
Sbjct: 337 RIDLSNN 343



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 23/62 (37%), Positives = 37/62 (59%), Gaps = 1/62 (1%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCAS 115
           L L NN++ ++P  +F+H+P+L+T  +  N   CDC L +L  WL  R P   L  +C+ 
Sbjct: 186 LTLNNNNITTIPVSSFNHMPKLRTFRLHSNHLFCDCHLAWLSQWLRQR-PTIGLFTQCSG 244

Query: 116 PS 117
           P+
Sbjct: 245 PA 246



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 1/71 (1%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRC 113
           R L L +N + +V PGAFD L  L TL++  NP++C+C L +L  WL  R        RC
Sbjct: 640 RLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKR-KIVTGNPRC 698

Query: 114 ASPSLAAHGPL 124
            +P      PL
Sbjct: 699 QNPDFLRQIPL 709



 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 1/72 (1%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCAS 115
           L L +N +QS+  G F  L  +QTL + QNP+ CDC+L +L  +L    P      RCAS
Sbjct: 410 LSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLADFLR-TNPIETSGARCAS 468

Query: 116 PSLAAHGPLGRL 127
           P   A+  +G++
Sbjct: 469 PRRLANKRIGQI 480



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 33/96 (34%), Positives = 43/96 (44%), Gaps = 17/96 (17%)

Query: 2  PAWGAL---------FLLWATAE--ATKDCPSPCTCRALETMGLWVDCRGHGLTALPA-L 49
          P WG+           LLWA A       CP+ CTC      G  VDC G GL A+P  +
Sbjct: 5  PGWGSSAGPVRPELWLLLWAAAWRLGASACPALCTCT-----GTTVDCHGTGLQAIPKNI 59

Query: 50 PARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
          P  T  L L  N++  +    F  L QL+ L + +N
Sbjct: 60 PRNTERLELNGNNITRIHKNDFAGLKQLRVLQLMEN 95



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 1/63 (1%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRC 113
           R L L  N + ++  G F  +  L  L +  NP +CDC L +L  W++    E  +  RC
Sbjct: 835 RLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSSWVKTGYKEPGI-ARC 893

Query: 114 ASP 116
           A P
Sbjct: 894 AGP 896


>gi|11321571 slit homolog 3 [Homo sapiens]
          Length = 1523

 Score = 55.5 bits (132), Expect = 2e-08
 Identities = 28/67 (41%), Positives = 40/67 (59%), Gaps = 6/67 (8%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLANNSLQSVPPGAFDHLPQLQ 78
           CPSPCTC         VDCRG GL  +PA LP     + L  NS++++P GAF    +L+
Sbjct: 280 CPSPCTCS-----NNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLK 334

Query: 79  TLDVTQN 85
            +D+++N
Sbjct: 335 RIDISKN 341



 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 27/63 (42%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRC 113
           R L L  N + SVP G+F+ L  L  L +  NP HCDCSL +L  W++    E  +  RC
Sbjct: 826 RVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGI-ARC 884

Query: 114 ASP 116
           +SP
Sbjct: 885 SSP 887



 Score = 50.4 bits (119), Expect = 8e-07
 Identities = 27/72 (37%), Positives = 41/72 (56%), Gaps = 1/72 (1%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCAS 115
           L L +N LQ++  G F  L  +QTL + QNP+ CDC L +L  +L+D  P      RC+S
Sbjct: 408 LSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQD-NPIETSGARCSS 466

Query: 116 PSLAAHGPLGRL 127
           P   A+  + ++
Sbjct: 467 PRRLANKRISQI 478



 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 20/50 (40%), Positives = 31/50 (62%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDR 103
           R L L +N + ++ PGAF  L  L T+++  NP++C+C L +L  WL  R
Sbjct: 632 RLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKR 681



 Score = 43.9 bits (102), Expect = 7e-05
 Identities = 18/48 (37%), Positives = 30/48 (62%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDR 103
           L L NN++  +   +F+H+P+++TL +  N  +CDC L +L  WL  R
Sbjct: 186 LTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQR 233



 Score = 35.0 bits (79), Expect = 0.034
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 30/91 (32%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTALP-ALPART------------------------R 54
           CP+ CTC A       VDC G GL A+P  +P                           R
Sbjct: 34  CPTKCTCSAAS-----VDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLR 88

Query: 55  HLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
            L L +N +  +  GAF  L QL+ L + +N
Sbjct: 89  VLHLEDNQVSVIERGAFQDLKQLERLRLNKN 119



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 25/92 (27%), Positives = 33/92 (35%), Gaps = 31/92 (33%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTALPA-LPA-------------------------RT 53
           CP  C C      G  VDC    L  +P+ LP                            
Sbjct: 505 CPEKCRCE-----GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNL 559

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           R + L+NN ++ V  GAFD    +Q L +T N
Sbjct: 560 RKINLSNNKIKEVREGAFDGAASVQELMLTGN 591


>gi|122937470 carboxypeptidase N, polypeptide 2, 83kD [Homo sapiens]
          Length = 545

 Score = 54.3 bits (129), Expect = 5e-08
 Identities = 46/133 (34%), Positives = 63/133 (47%), Gaps = 16/133 (12%)

Query: 41  HGLTAL-PAL---PARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYL 96
           + LTAL PAL    ++   L L+ N L ++P G FD    L  L +  NPW CDC L YL
Sbjct: 347 NNLTALHPALFQNLSKLELLSLSKNQLTTLPEGIFDTNYNLFNLALHGNPWQCDCHLAYL 406

Query: 97  RLWLEDRTPEAL-LQVRCASPSLAAHGPLGRLTGYQL------GSCGWQLQASW---VRP 146
             WL+  T   L +Q  CA P+      +  L   QL         G+Q+  +W    + 
Sbjct: 407 FNWLQQYTDRLLNIQTYCAGPAYLKGQVVPALNEKQLVCPVTRDHLGFQV--TWPDESKA 464

Query: 147 GVLWDVALVAVAA 159
           G  WD+A+   AA
Sbjct: 465 GGSWDLAVQERAA 477



 Score = 28.5 bits (62), Expect = 3.2
 Identities = 26/105 (24%), Positives = 39/105 (37%), Gaps = 33/105 (31%)

Query: 4   WGALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLANNS 62
           W +L LL   A   + CP  C C   E     V C    L  +P  +P  T++++    S
Sbjct: 9   WTSLLLL---ARPAQPCPMGCDCFVQE-----VFCSDEELATVPLDIPPYTKNIIFVETS 60

Query: 63  LQSVP------------------------PGAFDHLPQLQTLDVT 83
             ++                         P AF  LP+L+ L+VT
Sbjct: 61  FTTLETRAFGSNPNLTKVVFLNTQLCQFRPDAFGGLPRLEDLEVT 105



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 23/67 (34%), Positives = 32/67 (47%), Gaps = 13/67 (19%)

Query: 41  HGLTALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTL-----DVTQNPWHCDCSLTY 95
           H LT+L  L        L+NN+L  +P G F  L  LQ L     ++++ P      L  
Sbjct: 190 HPLTSLQTLK-------LSNNALSGLPQGVFGKLGSLQELFLDSNNISELPPQVFSQLFC 242

Query: 96  L-RLWLE 101
           L RLWL+
Sbjct: 243 LERLWLQ 249



 Score = 26.9 bits (58), Expect = 9.3
 Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 7/68 (10%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCAS 115
           L L +N L++V  G F HL  L++L ++ N      ++T+L   +  R  E L+++   S
Sbjct: 294 LSLTHNQLETVAEGTFAHLSNLRSLMLSYN------AITHLPAGI-FRDLEELVKLYLGS 346

Query: 116 PSLAAHGP 123
            +L A  P
Sbjct: 347 NNLTALHP 354


>gi|194306623 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 53.5 bits (127), Expect = 9e-08
 Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 45  ALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLED-- 102
           AL ALP   R L + NN L+++ PG FD L  L  L +  NP+HC C L +L+ W     
Sbjct: 142 ALGALPD-LRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTR 200

Query: 103 -RTPEALLQVRCASPSLAAHGPLGRL 127
              PE    + CASP      P+ RL
Sbjct: 201 VSLPEP-DSIACASPPALQGVPVYRL 225



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 31/123 (25%)

Query: 6   ALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALP-ALPA------------- 51
           AL+L+WA       CP PC C   +    + DC    L  +P  LPA             
Sbjct: 6   ALWLVWALLGVAGSCPEPCAC-VDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT 64

Query: 52  -----------RTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN-----PWHCDCSLTY 95
                      +   L LA+N +++V PGA   L QL+ LD++ N     PW    +L+ 
Sbjct: 65  VLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSA 124

Query: 96  LRL 98
           L+L
Sbjct: 125 LQL 127


>gi|194306621 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 53.5 bits (127), Expect = 9e-08
 Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 45  ALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLED-- 102
           AL ALP   R L + NN L+++ PG FD L  L  L +  NP+HC C L +L+ W     
Sbjct: 142 ALGALPD-LRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTR 200

Query: 103 -RTPEALLQVRCASPSLAAHGPLGRL 127
              PE    + CASP      P+ RL
Sbjct: 201 VSLPEP-DSIACASPPALQGVPVYRL 225



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 31/123 (25%)

Query: 6   ALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALP-ALPA------------- 51
           AL+L+WA       CP PC C   +    + DC    L  +P  LPA             
Sbjct: 6   ALWLVWALLGVAGSCPEPCAC-VDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT 64

Query: 52  -----------RTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN-----PWHCDCSLTY 95
                      +   L LA+N +++V PGA   L QL+ LD++ N     PW    +L+ 
Sbjct: 65  VLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSA 124

Query: 96  LRL 98
           L+L
Sbjct: 125 LQL 127


>gi|39930401 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 53.5 bits (127), Expect = 9e-08
 Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 45  ALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLED-- 102
           AL ALP   R L + NN L+++ PG FD L  L  L +  NP+HC C L +L+ W     
Sbjct: 142 ALGALPD-LRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTR 200

Query: 103 -RTPEALLQVRCASPSLAAHGPLGRL 127
              PE    + CASP      P+ RL
Sbjct: 201 VSLPEP-DSIACASPPALQGVPVYRL 225



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 31/123 (25%)

Query: 6   ALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALP-ALPA------------- 51
           AL+L+WA       CP PC C   +    + DC    L  +P  LPA             
Sbjct: 6   ALWLVWALLGVAGSCPEPCAC-VDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT 64

Query: 52  -----------RTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN-----PWHCDCSLTY 95
                      +   L LA+N +++V PGA   L QL+ LD++ N     PW    +L+ 
Sbjct: 65  VLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSA 124

Query: 96  LRL 98
           L+L
Sbjct: 125 LQL 127


>gi|194306618 immunoglobulin superfamily containing leucine-rich
           repeat 2 [Homo sapiens]
          Length = 745

 Score = 53.5 bits (127), Expect = 9e-08
 Identities = 34/86 (39%), Positives = 44/86 (51%), Gaps = 5/86 (5%)

Query: 45  ALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLED-- 102
           AL ALP   R L + NN L+++ PG FD L  L  L +  NP+HC C L +L+ W     
Sbjct: 142 ALGALPD-LRSLRINNNRLRTLAPGTFDALSALSHLQLYHNPFHCGCGLVWLQAWAASTR 200

Query: 103 -RTPEALLQVRCASPSLAAHGPLGRL 127
              PE    + CASP      P+ RL
Sbjct: 201 VSLPEP-DSIACASPPALQGVPVYRL 225



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 31/123 (25%)

Query: 6   ALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALP-ALPA------------- 51
           AL+L+WA       CP PC C   +    + DC    L  +P  LPA             
Sbjct: 6   ALWLVWALLGVAGSCPEPCAC-VDKYAHQFADCAYKELREVPEGLPANVTTLSLSANKIT 64

Query: 52  -----------RTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN-----PWHCDCSLTY 95
                      +   L LA+N +++V PGA   L QL+ LD++ N     PW    +L+ 
Sbjct: 65  VLRRGAFADVTQVTSLWLAHNEVRTVEPGALAVLSQLKNLDLSHNFISSFPWSDLRNLSA 124

Query: 96  LRL 98
           L+L
Sbjct: 125 LQL 127


>gi|4759146 slit homolog 2 [Homo sapiens]
          Length = 1529

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 6/67 (8%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLANNSLQSVPPGAFDHLPQLQ 78
           CP+ CTC         VDCRG GLT +P  LP     + L  N+++ +PPGAF    +L+
Sbjct: 273 CPAACTCS-----NNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYKKLR 327

Query: 79  TLDVTQN 85
            +D++ N
Sbjct: 328 RIDLSNN 334



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 1/62 (1%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCAS 115
           L L NN++  +   +F+H+P+L+T  +  N  +CDC L +L  WL  R P   L  +C  
Sbjct: 180 LTLNNNNITRLSVASFNHMPKLRTFRLHSNNLYCDCHLAWLSDWLRQR-PRVGLYTQCMG 238

Query: 116 PS 117
           PS
Sbjct: 239 PS 240



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 26/72 (36%), Positives = 39/72 (54%), Gaps = 1/72 (1%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCAS 115
           L L +N LQ++  G F  L  +QT+ + QNP+ CDC L +L  +L    P      RC S
Sbjct: 401 LSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADYLH-TNPIETSGARCTS 459

Query: 116 PSLAAHGPLGRL 127
           P   A+  +G++
Sbjct: 460 PRRLANKRIGQI 471



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 22/50 (44%), Positives = 32/50 (64%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDR 103
           R L L +N + +V PGAFD L  L TL++  NP++C+C L +L  WL  +
Sbjct: 633 RLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKK 682



 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 28/78 (35%), Positives = 39/78 (50%), Gaps = 8/78 (10%)

Query: 46  LPALPART-------RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRL 98
           L  +P RT       R L L  N +  VP GAF+ L  L  L +  NP +CDC++ +L  
Sbjct: 813 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 872

Query: 99  WLEDRTPEALLQVRCASP 116
           W++    E  +  RCA P
Sbjct: 873 WVKSEYKEPGI-ARCAGP 889


>gi|205360962 polycystin 1 isoform 2 precursor [Homo sapiens]
          Length = 4302

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 40/140 (28%), Positives = 55/140 (39%), Gaps = 33/140 (23%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTAL-PAL--PA------------------------R 52
           C  PC C         V+C G GL  L PAL  PA                         
Sbjct: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSA 92

Query: 53  TRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVR 112
              L ++NN + ++  G F +L  L  ++++ NP+ CDC L +L  W E++      QVR
Sbjct: 93  LAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQ------QVR 146

Query: 113 CASPSLAAHGPLGRLTGYQL 132
              P  A     G L G  L
Sbjct: 147 VVQPEAATCAGPGSLAGQPL 166


>gi|205360954 polycystin 1 isoform 1 precursor [Homo sapiens]
          Length = 4303

 Score = 52.4 bits (124), Expect = 2e-07
 Identities = 40/140 (28%), Positives = 55/140 (39%), Gaps = 33/140 (23%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTAL-PAL--PA------------------------R 52
           C  PC C         V+C G GL  L PAL  PA                         
Sbjct: 33  CEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSA 92

Query: 53  TRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVR 112
              L ++NN + ++  G F +L  L  ++++ NP+ CDC L +L  W E++      QVR
Sbjct: 93  LAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQ------QVR 146

Query: 113 CASPSLAAHGPLGRLTGYQL 132
              P  A     G L G  L
Sbjct: 147 VVQPEAATCAGPGSLAGQPL 166


>gi|40217825 slit and trk like 6 [Homo sapiens]
          Length = 841

 Score = 52.0 bits (123), Expect = 3e-07
 Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 2/75 (2%)

Query: 55  HLLLANNSLQSVP-PGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALL-QVR 112
           HL L  N LQ++P  G  +H+ ++  L +  N W C+C L  L+ WLE+  P++++  V 
Sbjct: 187 HLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNKWACNCDLLQLKTWLENMPPQSIIGDVV 246

Query: 113 CASPSLAAHGPLGRL 127
           C SP       L RL
Sbjct: 247 CNSPPFFKGSILSRL 261



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 18/50 (36%), Positives = 26/50 (52%), Gaps = 3/50 (6%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTALPAL---PARTRHLLLANNSLQSV 66
           CP PC C+ L   GL + C+   + +L  L   P   R L+LA N + S+
Sbjct: 329 CPIPCNCKVLSPSGLLIHCQERNIESLSDLRPPPQNPRKLILAGNIIHSL 378



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 25/86 (29%)

Query: 56  LLLANNSLQSVPP---------------GAFDHLPQ---------LQTLDVTQNPWHCDC 91
           L L NN LQ +PP                 F HLP          L  +D+  NPW C C
Sbjct: 464 LYLNNNLLQVLPPHIFSGVPLTKVNLKTNQFTHLPVSNILDDLDLLTQIDLEDNPWDCSC 523

Query: 92  SLTYLRLWLEDRTPEALL-QVRCASP 116
            L  L+ W++  +   +   + C SP
Sbjct: 524 DLVGLQQWIQKLSKNTVTDDILCTSP 549


>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
           [Homo sapiens]
          Length = 1093

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 34/90 (37%), Positives = 42/90 (46%), Gaps = 16/90 (17%)

Query: 7   LFLLW----------ATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRH 55
           L LLW          A A     C + CTC      G  +DC G GL ALP  LP+ TR 
Sbjct: 18  LLLLWLLLLRLEPVTAAAGPRAPCAAACTCA-----GDSLDCGGRGLAALPGDLPSWTRS 72

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L L+ N L  + P  F+ LP LQ + +  N
Sbjct: 73  LNLSYNKLSEIDPAGFEDLPNLQEVYLNNN 102



 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 22/62 (35%), Positives = 34/62 (54%)

Query: 55  HLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCA 114
           HL L  N+++SV   AF  +  L+ L ++ + + CDC L +L  WL  R  +A +   CA
Sbjct: 410 HLNLGGNAIRSVQFDAFVKMKNLKELHISSDSFLCDCQLKWLPPWLIGRMLQAFVTATCA 469

Query: 115 SP 116
            P
Sbjct: 470 HP 471


>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
          Length = 713

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 25/74 (33%), Positives = 39/74 (52%), Gaps = 3/74 (4%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCAS 115
           L L++N+L S+P   F  L +L+ + +  NPWHC+C + +L  WL++  P       C +
Sbjct: 282 LNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPS---NTTCCA 338

Query: 116 PSLAAHGPLGRLTG 129
              A  G  GR  G
Sbjct: 339 RCHAPAGLKGRYIG 352



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 22/67 (32%), Positives = 32/67 (47%), Gaps = 4/67 (5%)

Query: 20  CPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLANNSLQSVPPGAFDHLPQLQ 78
           CP  C+C         V C    L  +PA +P  TR+L L  N +Q +    F HL  L+
Sbjct: 57  CPVACSC---SNQASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLE 113

Query: 79  TLDVTQN 85
            L +++N
Sbjct: 114 ILQLSKN 120



 Score = 32.0 bits (71), Expect = 0.29
 Identities = 13/32 (40%), Positives = 22/32 (68%)

Query: 51  ARTRHLLLANNSLQSVPPGAFDHLPQLQTLDV 82
           ++ R L L NN ++S+P  AF+ +P L+ LD+
Sbjct: 158 SKLRELWLRNNPIESIPSYAFNRVPSLRRLDL 189


>gi|239752702 PREDICTED: leucine rich repeat containing 38, partial
           [Homo sapiens]
          Length = 254

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 11/114 (9%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLED---RTPEALLQVR 112
           L L +N+L+S+   A   LP L++L +  NPW CDC   +L  W+++   + P+ L +++
Sbjct: 117 LELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQ 176

Query: 113 CASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLA 166
           C+ P  +    L  L+      C + L         L D+ ++  + + +++ A
Sbjct: 177 CSLPMESRRISLRELSEASFSECRFSLS--------LTDLCIIIFSGVAVSIAA 222



 Score = 27.3 bits (59), Expect = 7.1
 Identities = 22/74 (29%), Positives = 30/74 (40%), Gaps = 25/74 (33%)

Query: 37 DCRGHGLTALP-ALPARTRHLLLA------------------------NNSLQSVPPGAF 71
          DCR  GL ++P   P   R LL+A                        NNSL+S+  G F
Sbjct: 1  DCRDRGLPSVPDPFPLDVRKLLVAGNRIQRIPEDFFIFYGDLVYLDFRNNSLRSLEEGTF 60

Query: 72 DHLPQLQTLDVTQN 85
              +L  LD++ N
Sbjct: 61 SGSAKLVFLDLSYN 74


>gi|239747236 PREDICTED: leucine rich repeat containing 38 [Homo
           sapiens]
          Length = 408

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 11/114 (9%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLED---RTPEALLQVR 112
           L L +N+L+S+   A   LP L++L +  NPW CDC   +L  W+++   + P+ L +++
Sbjct: 271 LELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQ 330

Query: 113 CASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLA 166
           C+ P  +    L  L+      C + L         L D+ ++  + + +++ A
Sbjct: 331 CSLPMESRRISLRELSEASFSECRFSLS--------LTDLCIIIFSGVAVSIAA 376


>gi|239741057 PREDICTED: leucine rich repeat containing 38 [Homo
           sapiens]
          Length = 408

 Score = 51.2 bits (121), Expect = 5e-07
 Identities = 29/114 (25%), Positives = 57/114 (50%), Gaps = 11/114 (9%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLED---RTPEALLQVR 112
           L L +N+L+S+   A   LP L++L +  NPW CDC   +L  W+++   + P+ L +++
Sbjct: 271 LELNDNNLRSLSVAALAALPALRSLRLDGNPWLCDCDFAHLFSWIQENASKLPKGLDEIQ 330

Query: 113 CASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALVAVAALGLALLA 166
           C+ P  +    L  L+      C + L         L D+ ++  + + +++ A
Sbjct: 331 CSLPMESRRISLRELSEASFSECRFSLS--------LTDLCIIIFSGVAVSIAA 376


>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
          Length = 2623

 Score = 50.8 bits (120), Expect = 6e-07
 Identities = 25/71 (35%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRC 113
           + L L++N L S+P     ++P L +L +  NPW CDC L +L  W++++ P+ +   + 
Sbjct: 188 KFLYLSDNFLTSLPQEMVSYMPDLDSLYLHGNPWTCDCHLKWLSDWIQEK-PDVIKCKKD 246

Query: 114 ASPSLAAHGPL 124
            SPS A   PL
Sbjct: 247 RSPSSAQQCPL 257


>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
          Length = 334

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 33/89 (37%), Positives = 42/89 (47%), Gaps = 14/89 (15%)

Query: 10  LWATAEATK---------DCPSPCTCRALETMGLWVDCRGHGLTALP-ALPARTRHLLLA 59
           +WA   AT          DCP  CTC      G    C    L A+P  L  R R LLL 
Sbjct: 24  VWAQVSATASPSGSLGAPDCPEVCTC----VPGGLASCSALSLPAVPPGLSLRLRALLLD 79

Query: 60  NNSLQSVPPGAFDHLPQLQTLDVTQNPWH 88
           +N ++++PPGAF     LQ LD+ +N  H
Sbjct: 80  HNRVRALPPGAFAGAGALQRLDLRENGLH 108



 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 37/113 (32%), Positives = 46/113 (40%), Gaps = 11/113 (9%)

Query: 45  ALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRT 104
           AL ALP   R L L +N L ++ PG    LP L  L +  NPW C C+L  L  WL    
Sbjct: 162 ALGALPL-LRSLSLQDNELAALAPGLLGRLPALDALHLRGNPWGCGCALRPLCAWLRRHP 220

Query: 105 PEA--LLQVRCASPSLAAHGPLGRLTGYQLGSCGWQLQASWVRPGVLWDVALV 155
             A     V C  P      PL   +      C         +P  L D+A+V
Sbjct: 221 LPASEAETVLCVWPGRLTLSPLTAFSDAAFSHC--------AQPLALRDLAVV 265


>gi|194272183 G protein-coupled receptor 124 [Homo sapiens]
          Length = 1338

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 28/81 (34%), Positives = 39/81 (48%)

Query: 52  RTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQV 111
           R   L ++ N   S+ PG FD LP L+ +D+      CDC L +L  W ++R+ +     
Sbjct: 157 RLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHT 216

Query: 112 RCASPSLAAHGPLGRLTGYQL 132
            CA PS      LG L   QL
Sbjct: 217 LCAYPSALHAQALGSLQEAQL 237



 Score = 30.8 bits (68), Expect = 0.64
 Identities = 30/95 (31%), Positives = 36/95 (37%), Gaps = 16/95 (16%)

Query: 7   LFLLWATAEATKDCP---SPCTCRALETMGLW----------VDCRGHGLTALPA---LP 50
           L LL   A     CP     C C      GL           V C G  L   P    LP
Sbjct: 24  LLLLAPEARGAPGCPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPPEPGLLP 83

Query: 51  ARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
             T  LLL+NN +  +  G+F  L  L+ LD+  N
Sbjct: 84  NGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNN 118



 Score = 30.8 bits (68), Expect = 0.64
 Identities = 16/38 (42%), Positives = 23/38 (60%)

Query: 58  LANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTY 95
           L NN + +V PGAF  L +L+ LD++ N   C  S T+
Sbjct: 115 LRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETF 152


>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
           sapiens]
          Length = 674

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 5/62 (8%)

Query: 58  LANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVR---CA 114
           L+NN+L ++P G FD L  L  L +  NPW C C+L +LR W++ R   A++ VR   C 
Sbjct: 301 LSNNNLTTLPRGLFDDLGNLAQLLLRNNPWFCGCNLMWLRDWVKARA--AVVNVRGLMCQ 358

Query: 115 SP 116
            P
Sbjct: 359 GP 360


>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
           sapiens]
          Length = 660

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 1/59 (1%)

Query: 43  LTALPALPARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLE 101
           LTA   L  +   L ++NN L+ +  G FD+L  L+ L    NPW CDCS+ ++  WL+
Sbjct: 269 LTAFSNL-RKLERLDISNNQLRMLTQGVFDNLSNLKQLTARNNPWFCDCSIKWVTEWLK 326


>gi|21281681 leucine-rich repeat LGI family, member 3 [Homo sapiens]
          Length = 548

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 26/62 (41%), Positives = 35/62 (56%), Gaps = 1/62 (1%)

Query: 55  HLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCA 114
           HL LANN+LQ++P   F  L  L  LD+  N  +CDC + +L  WL   T   +  + CA
Sbjct: 140 HLSLANNNLQTLPRDIFRPLDILNDLDLRGNSLNCDCKVKWLVEWLA-HTNTTVAPIYCA 198

Query: 115 SP 116
           SP
Sbjct: 199 SP 200



 Score = 35.8 bits (81), Expect = 0.020
 Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 11/89 (12%)

Query: 1  MPAWGALFLLWATAEA---TKDCPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHL 56
          + A G   +L  +A+    T  CP  C+C         VD +     A+P  LP+    L
Sbjct: 17 LSALGFCLMLQVSAKRPPKTPPCPPSCSCT--RDTAFCVDSK-----AVPRNLPSEVISL 69

Query: 57 LLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L N +   +  GAF HLP LQ L +  N
Sbjct: 70 TLVNAAFSEIQDGAFSHLPLLQFLLLNSN 98


>gi|30425563 reticulon 4 receptor-like 2 [Homo sapiens]
          Length = 420

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 27/66 (40%), Positives = 34/66 (51%), Gaps = 1/66 (1%)

Query: 51  ARTRHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQ 110
           +R   L L NNSL S+P  A   LP L+ L +  NPW CDC    L  W + R   +   
Sbjct: 227 SRLTILYLFNNSLASLPGEALADLPSLEFLRLNANPWACDCRARPLWAWFQ-RARVSSSD 285

Query: 111 VRCASP 116
           V CA+P
Sbjct: 286 VTCATP 291



 Score = 40.4 bits (93), Expect = 8e-04
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 26/102 (25%)

Query: 7   LFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALP-ALPARTRHLLLANN---- 61
           L +L A   A   CP  CTC +       V C+ +  +++P +LP  T+ L L NN    
Sbjct: 18  LLMLLALPLAAPSCPMLCTCYSSPPT---VSCQANNFSSVPLSLPPSTQRLFLQNNLIRT 74

Query: 62  ------------------SLQSVPPGAFDHLPQLQTLDVTQN 85
                             +L ++ PG F HL  L+ LD+  N
Sbjct: 75  LRPGTFGSNLLTLWLFSNNLSTIYPGTFRHLQALEELDLGDN 116


>gi|52353306 leucine rich repeat containing 55 [Homo sapiens]
          Length = 341

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 6/73 (8%)

Query: 14  AEATKDCPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLANNSLQSVPPGAFD 72
           ++A   CP  CTCR        VDC    L ++P  LP  TR+L LA+N + +VPPG   
Sbjct: 75  SDAGTSCPVLCTCR-----NQVVDCSSQRLFSVPPDLPMDTRNLSLAHNRITAVPPGYLT 129

Query: 73  HLPQLQTLDVTQN 85
              +LQ LD+  N
Sbjct: 130 CYMELQVLDLHNN 142



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 5/86 (5%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDR----TPEALL 109
           R L L+   L  +   A + LP L TL +  NPW C C++  L  WL +R    T ++ L
Sbjct: 208 RDLDLSYGGLAFLSLEALEGLPGLVTLQIGGNPWVCGCTMEPLLKWLRNRIQRCTADSQL 267

Query: 110 QVRCASPSLAAHGPLGRLTGYQLGSC 135
              C  P      PL  LT     +C
Sbjct: 268 -AECRGPPEVEGAPLFSLTEESFKAC 292


>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
           sapiens]
          Length = 587

 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 21/43 (48%), Positives = 27/43 (62%)

Query: 58  LANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWL 100
           L NN L+++P G FDHL +L  L +  NPW CD  +  LR WL
Sbjct: 402 LQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWL 444



 Score = 34.7 bits (78), Expect = 0.044
 Identities = 27/100 (27%), Positives = 36/100 (36%), Gaps = 29/100 (29%)

Query: 11  WATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLAN--------- 60
           W    A   CPS CTC    +    V+C G  + A+P  LP     L + N         
Sbjct: 22  WGAGLAYHGCPSECTC----SRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNES 77

Query: 61  ---------------NSLQSVPPGAFDHLPQLQTLDVTQN 85
                          N L  + PGAF +L  L+ L +  N
Sbjct: 78  PFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANN 117



 Score = 30.8 bits (68), Expect = 0.64
 Identities = 15/32 (46%), Positives = 21/32 (65%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           R+L LANN LQ +P G F  L  L++L ++ N
Sbjct: 110 RYLSLANNKLQVLPIGLFQGLDSLESLLLSSN 141



 Score = 30.4 bits (67), Expect = 0.84
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           + L L  N L+ +P GAFDHL  L  L++ +N
Sbjct: 158 KELQLHGNHLEYIPDGAFDHLVGLTKLNLGKN 189



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           + L L+NN +  +PP  F  LPQL  L +  N
Sbjct: 254 QRLYLSNNHISQLPPSIFMQLPQLNRLTLFGN 285



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           R L L +N + S+P   F +L QLQ L +++N
Sbjct: 302 RELWLYDNHISSLPDNVFSNLRQLQVLILSRN 333



 Score = 27.3 bits (59), Expect = 7.1
 Identities = 14/30 (46%), Positives = 16/30 (53%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L L  N L  +P G FD L  LQ L + QN
Sbjct: 208 LRLYENRLTDIPMGTFDGLVNLQELALQQN 237



 Score = 26.9 bits (58), Expect = 9.3
 Identities = 13/30 (43%), Positives = 16/30 (53%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L L  NSL  + P  F HL  LQ L + +N
Sbjct: 184 LNLGKNSLTHISPRVFQHLGNLQVLRLYEN 213



 Score = 26.9 bits (58), Expect = 9.3
 Identities = 11/30 (36%), Positives = 19/30 (63%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L+L+ N +  + PGAF+ L +L+ L +  N
Sbjct: 328 LILSRNQISFISPGAFNGLTELRELSLHTN 357


>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
           sapiens]
          Length = 581

 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 21/43 (48%), Positives = 27/43 (62%)

Query: 58  LANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWL 100
           L NN L+++P G FDHL +L  L +  NPW CD  +  LR WL
Sbjct: 396 LQNNQLENLPLGIFDHLGKLCELRLYDNPWRCDSDILPLRNWL 438



 Score = 34.7 bits (78), Expect = 0.044
 Identities = 27/100 (27%), Positives = 36/100 (36%), Gaps = 29/100 (29%)

Query: 11  WATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPA-LPARTRHLLLAN--------- 60
           W    A   CPS CTC    +    V+C G  + A+P  LP     L + N         
Sbjct: 16  WGAGLAYHGCPSECTC----SRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNES 71

Query: 61  ---------------NSLQSVPPGAFDHLPQLQTLDVTQN 85
                          N L  + PGAF +L  L+ L +  N
Sbjct: 72  PFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANN 111



 Score = 30.8 bits (68), Expect = 0.64
 Identities = 15/32 (46%), Positives = 21/32 (65%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           R+L LANN LQ +P G F  L  L++L ++ N
Sbjct: 104 RYLSLANNKLQVLPIGLFQGLDSLESLLLSSN 135



 Score = 30.4 bits (67), Expect = 0.84
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           + L L  N L+ +P GAFDHL  L  L++ +N
Sbjct: 152 KELQLHGNHLEYIPDGAFDHLVGLTKLNLGKN 183



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           + L L+NN +  +PP  F  LPQL  L +  N
Sbjct: 248 QRLYLSNNHISQLPPSIFMQLPQLNRLTLFGN 279



 Score = 28.1 bits (61), Expect = 4.2
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 54  RHLLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           R L L +N + S+P   F +L QLQ L +++N
Sbjct: 296 RELWLYDNHISSLPDNVFSNLRQLQVLILSRN 327



 Score = 27.3 bits (59), Expect = 7.1
 Identities = 14/30 (46%), Positives = 16/30 (53%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L L  N L  +P G FD L  LQ L + QN
Sbjct: 202 LRLYENRLTDIPMGTFDGLVNLQELALQQN 231



 Score = 26.9 bits (58), Expect = 9.3
 Identities = 13/30 (43%), Positives = 16/30 (53%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L L  NSL  + P  F HL  LQ L + +N
Sbjct: 178 LNLGKNSLTHISPRVFQHLGNLQVLRLYEN 207



 Score = 26.9 bits (58), Expect = 9.3
 Identities = 11/30 (36%), Positives = 19/30 (63%)

Query: 56  LLLANNSLQSVPPGAFDHLPQLQTLDVTQN 85
           L+L+ N +  + PGAF+ L +L+ L +  N
Sbjct: 322 LILSRNQISFISPGAFNGLTELRELSLHTN 351


>gi|21313638 leucine-rich repeat LGI family, member 2 [Homo sapiens]
          Length = 545

 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 1/76 (1%)

Query: 55  HLLLANNSLQSVPPGAFDHLPQLQTLDVTQNPWHCDCSLTYLRLWLEDRTPEALLQVRCA 114
           HL LANN ++++P   F  L  L  LD+  N + CDC   +L LWL+  T   +  V C 
Sbjct: 137 HLSLANNHIKALPRDVFSDLDSLIELDLRGNKFECDCKAKWLYLWLK-MTNSTVSDVLCI 195

Query: 115 SPSLAAHGPLGRLTGY 130
            P       L  +T +
Sbjct: 196 GPPEYQEKKLNDVTSF 211



 Score = 28.9 bits (63), Expect = 2.4
 Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 6/82 (7%)

Query: 5  GALFLLWATAEATKDCPSPCTCRALETMGLWVDCRGHGLTALPAL-PARTRHLLLANNSL 63
          GA  L+  +A+  +    P TC   +   + V     G + +P + P     L L N + 
Sbjct: 19 GAACLIPRSAQVRRLARCPATCSCTKESIICV-----GSSWVPRIVPGDISSLSLVNGTF 73

Query: 64 QSVPPGAFDHLPQLQTLDVTQN 85
            +    F HLP LQ L +  N
Sbjct: 74 SEIKDRMFSHLPSLQLLLLNSN 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.468 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,739,667
Number of Sequences: 37866
Number of extensions: 339930
Number of successful extensions: 1683
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1027
Number of HSP's gapped (non-prelim): 626
length of query: 177
length of database: 18,247,518
effective HSP length: 95
effective length of query: 82
effective length of database: 14,650,248
effective search space: 1201320336
effective search space used: 1201320336
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.