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Search of human proteins with 4503509
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503509 eukaryotic translation initiation factor 3, subunit
10 theta, 150/170kDa [Homo sapiens]
(1382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 2801 0.0
gi|148746195 trichohyalin [Homo sapiens] 183 9e-46
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 144 4e-34
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 140 6e-33
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 135 3e-31
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 125 3e-28
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 119 2e-26
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 115 2e-25
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 115 3e-25
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 112 2e-24
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 112 3e-24
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 111 4e-24
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 100 2e-20
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 100 2e-20
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 100 2e-20
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 99 2e-20
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 99 2e-20
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 97 1e-19
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 97 1e-19
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 95 5e-19
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 95 5e-19
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 94 7e-19
gi|219803769 trichoplein [Homo sapiens] 92 3e-18
gi|14150056 trichoplein [Homo sapiens] 92 3e-18
gi|146134388 YLP motif containing 1 [Homo sapiens] 91 6e-18
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 90 2e-17
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 90 2e-17
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 90 2e-17
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 90 2e-17
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 90 2e-17
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 2801 bits (7262), Expect = 0.0
Identities = 1382/1382 (100%), Positives = 1382/1382 (100%)
Query: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVD 60
MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVD
Sbjct: 1 MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQKIHEPIMLKYLELCVD 60
Query: 61 LRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDLDN 120
LRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDLDN
Sbjct: 61 LRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTEAAKEESQQMVLDIEDLDN 120
Query: 121 IQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQ 180
IQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQ
Sbjct: 121 IQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQCLDLLRNNSRVERLYHDIAQQ 180
Query: 181 AFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSA 240
AFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSA
Sbjct: 181 AFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAINLNNPESQSMHLETRLVQLDSA 240
Query: 241 ISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLY 300
ISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLY
Sbjct: 241 ISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYYNKVSTVFWKSGNALFHASTLHRLY 300
Query: 301 HLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLG 360
HLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLG
Sbjct: 301 HLSREMRKNLTQDEMQRMSTRVLLATLSIPITPERTDIARLLDMDGIIVEKQRRLATLLG 360
Query: 361 LQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEK 420
LQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEK
Sbjct: 361 LQAPPTRIGLINDMVRFNVLQYVVPEVKDLYNWLEVEFNPLKLCERVTKVLNWVREQPEK 420
Query: 421 EPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDL 480
EPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDL
Sbjct: 421 EPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDL 480
Query: 481 QVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPA 540
QVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPA
Sbjct: 481 QVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPA 540
Query: 541 HILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE 600
HILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE
Sbjct: 541 HILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE 600
Query: 601 LQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
LQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED
Sbjct: 601 LQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
Query: 661 LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK
Sbjct: 661 LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
Query: 721 DMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFE 780
DMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFE
Sbjct: 721 DMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFE 780
Query: 781 ERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEE 840
ERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEE
Sbjct: 781 ERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEE 840
Query: 841 LREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWR 900
LREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWR
Sbjct: 841 LREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWR 900
Query: 901 KGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRR 960
KGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRR
Sbjct: 901 KGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRR 960
Query: 961 GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRR 1020
GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRR
Sbjct: 961 GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRR 1020
Query: 1021 GLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPR 1080
GLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPR
Sbjct: 1021 GLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPR 1080
Query: 1081 RGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPW 1140
RGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPW
Sbjct: 1081 RGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPW 1140
Query: 1141 RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEE 1200
RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEE
Sbjct: 1141 RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEE 1200
Query: 1201 REWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWR 1260
REWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWR
Sbjct: 1201 REWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWR 1260
Query: 1261 DSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR 1320
DSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR
Sbjct: 1261 DSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR 1320
Query: 1321 VEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTV 1380
VEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTV
Sbjct: 1321 VEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTV 1380
Query: 1381 RR 1382
RR
Sbjct: 1381 RR 1382
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 183 bits (465), Expect = 9e-46
Identities = 204/875 (23%), Positives = 392/875 (44%), Gaps = 84/875 (9%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLN---IQREKEELEQREAE 600
+E+E++ + T K K + R++ ++E +E+L L ++RE++E EQ++
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQR 299
Query: 601 LQKV----RKAEEERLRQEAKEREKERILQEHE-----QIKKKTVRERLEQIKKTELGAK 651
L++ RK EEER Q+ + RE++ ++ E Q++++ R +Q+++ + +
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 652 AFKDIDIEDLEELDPDFIMAKQ----VEQLEKE---KKELQERLKNQEKKIDYFERAKRL 704
+ + E EE + +Q +QL +E ++E Q R + Q ++ R ++L
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 705 EEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRL 764
++ EE+R + +++ E+R+ Q ER L+ + R ++R +L
Sbjct: 420 RREQQLRREQEEER-HEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR--KQQL 476
Query: 765 KAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEE---QRRAEEQ 821
K ++ E+ + EE E+ R E++ R+ +EERR + +EEEE QR EQ
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ 536
Query: 822 MLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERR-----REEER 876
L+ +E R + KREEE R QER ++ + E+++R+ +L E ERR RE+E
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 877 RLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEER 936
RL + L R++ +++ R E E RR K + E R + + E R
Sbjct: 597 RL-EQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 937 PRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWR---NTD 993
+RL +E+ E + R+ R ++ R EE +R P W+ ++
Sbjct: 656 EQRLKREEEEERL----EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711
Query: 994 DDRPPRRIADEDR---GNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRR 1050
D ++ R G R + + RR E W+ +E+R R+ ++++ RR
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRR--RESELQWQ--EEERAHRQQQEEEQ--RR 765
Query: 1051 GGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDD--RGPRRGMDDDRGPRRGMDDDRG 1108
D W+ + R+ L R P R + R R + R + ++
Sbjct: 766 ----DFTWQWQAEEKSERGRQRL-SARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820
Query: 1109 PRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGP 1168
R+ + ++ +++++ RR +R ++D L +D R + R
Sbjct: 821 RRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQ---EDQERRRSQEQRRDQK 873
Query: 1169 WRPLVKPGGWREK-----EKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDP 1223
WR ++ R + + A +E ++ EE E RE+ R Q++E ++
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE 933
Query: 1224 ERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDL 1283
E+ + E + RE+R +R R E R + + + + ++RR ++ +
Sbjct: 934 EQLQQEEEQLLREEREKRRRQE---RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 1284 RERRDLRDDRDRRGPPLRSEREE--VSSWRRADDRKDDRVEERDPPRRVPPPALSRDRER 1341
RE +L+ + ++ LR ERE+ W R +KD+ +E + R R++ R
Sbjct: 991 REEEELQQEEEQL---LREEREKRRRQEWERQYRKKDELQQEEEQLLRE-----EREKRR 1042
Query: 1342 DRDREREGEKEKASWRAE-----KDRESLRRTKNE 1371
++RER+ +E+ + E ++RE+ RR + E
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077
Score = 176 bits (446), Expect = 1e-43
Identities = 215/880 (24%), Positives = 403/880 (45%), Gaps = 110/880 (12%)
Query: 541 HILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE 600
H +E ++ QL L+ RK R + ++R+ER + + + E++E +RE
Sbjct: 199 HETEEFPDEEQLRRRELLELRRK------GREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 601 LQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERL--EQIKKTELGAKAFKDIDI 658
L+K EEE+L++E +R++E LQE E+ +K R+ L E+ ++ + + ++ +
Sbjct: 253 LRK----EEEKLQEEEPQRQRE--LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 659 EDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQR 718
+E ++ + ++E++E QER + QE++ + R ++ E +E+
Sbjct: 307 RRKQE--------EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 719 IKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQ 778
++ L +QEEER QL RE+ L + ++ R +L+ +Q E++L++
Sbjct: 359 RREQQLRREQEEER-REQQLRREQQLRREQQLRRE--------QQLRREQQLRREQQLRR 409
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQ-----MLKEREERERAE 833
E++L E+ R E++ R+ +EE R E+E EQR EQ LK EE ER E
Sbjct: 410 -EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 834 RAKREEELR-----EYQERVKKLEEVERK----------KRQRELEIEERERRREEERRL 878
+ +R+++L+ E +ER KLEE ER+ +R++E E+R +R+EEE RL
Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERL 528
Query: 879 GDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSH---RRDEE 935
S + R R+ E + + + E R +E R ++E R R +E
Sbjct: 529 QQRLRSEQQLR---REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 936 RPRRLGDDEDR--EPSLRPDD-DRVPRRGMDDDRGPRRGPEEDR-----FSRRGADDDRP 987
R +RL +++ E L+ ++ +R+ + + R R PEE+R S + +
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 988 SWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRG 1047
R +R +R+ E+ ++ +R +E+R A+E++ R R
Sbjct: 646 QLRREQQERREQRLKREE----EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 1048 PRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRR------GMDDDRGPRR 1101
P+ + + R + PR+ G RR + + RR +++R R+
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRK----QEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757
Query: 1102 GMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRG 1161
++++ RR D W+ A++ R R P R + +L RA++ R+
Sbjct: 758 QQEEEQ--RR---DFTWQWQ-AEEKSERGRQRLSARPPLREQRERQL--RAEE----RQQ 805
Query: 1162 DDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREEN-D 1220
+ R P EKE+ R + +E + EE E + +ER + Q+ E+
Sbjct: 806 REQRFLPEE--------EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 1221 KDPERERDRERDVDREDRFR----RPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRE 1276
+D ER R +E+ D++ R++ R R PA + ++ + + + +R E
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917
Query: 1277 RDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADD----RKDDRVEERDPPRRVPP 1332
R+ RR + R R++ + + REE RR + RKD ++++++
Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 1333 PALSRDRERDRD-REREGEKEKASWRAEKDRESLRRTKNE 1371
P R +ER++ RE E +++ ++RE RR + E
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Score = 175 bits (443), Expect = 3e-43
Identities = 213/899 (23%), Positives = 412/899 (45%), Gaps = 125/899 (13%)
Query: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQ 602
LQE+E Q++ + ++E +++L + E + R E R++EEL+Q E +L
Sbjct: 1043 LQERERQYREE-----EELQQEEEQLLGEER---ETRRRQELERQYRKEEELQQEEEQL- 1093
Query: 603 KVRKAEEERLRQEAKE--REKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
+R+ E+R RQE + RE+E + QE EQ+ +RE E+ ++ EL + ++ +++
Sbjct: 1094 -LREEPEKRRRQERERQCREEEELQQEEEQL----LREEREKRRRQELERQYREEEEVQQ 1148
Query: 661 LEEL----DPDFIMAKQVEQLEKEKKELQ---ERLKNQEKKIDYFERAKRLEEIPLIKSA 713
EE +P+ +++E+ +E++ELQ E+L +E++ ER ++ E ++
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 714 YEEQRIKD----MDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQ 769
+QR +D DL Q E E+ ++ + +N R LED L + + Q
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQ 1268
Query: 770 SV---------------YEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEE 814
+ ++++ + F E ER + E ++R RK + RE+ EE+
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK 1328
Query: 815 QRRAE--------EQMLKEREE----RERAERAKREEELREYQERVKKLEEVERKKRQ-- 860
+RR E EQ+L+EREE R+ +R REEELR ++ K LEE +R +RQ
Sbjct: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQER 1388
Query: 861 --------RELEIEERERRREEER----RLGDSSLSRKDSRWGDRDSEGTWRKGPEADSE 908
++L +ERE++ ++R R + LSR++ RD RK E + +
Sbjct: 1389 ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE-----RD-----RKFREEEQQ 1438
Query: 909 WRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGP 968
RR E+++ E + HR+ E + L + E+++ + D
Sbjct: 1439 VRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD-------------- 1484
Query: 969 RRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGS 1028
R+ EE++ RR D + + P R+ +E++ R + R+ L E++
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ----QRQRKFLQEEQQL 1540
Query: 1029 WRTADEDRGPRRGMDDDRGPRRGGA-DDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDR 1087
R ++RG +R D DR R ER + + +R + L++ + R+ +
Sbjct: 1541 RR---QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE--- 1594
Query: 1088 GPRRGMDDDRGPRR--GMDDDRGPR-RGLDDDRGPWRNADDDRIPRRGAE----DDRGPW 1140
R+ M+D++ RR G R R R +D + ++ ++ R+ + ++
Sbjct: 1595 --RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 1141 RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEE 1200
R + ++ R D +F + G + L + R+ + ++ RE + +E
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 1201 REWDREKERDR----DNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEES 1256
+ R +E +R + Q R+E +++ R ++R R + E++ R R+E RR E
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR--QERD 1770
Query: 1257 SSWRDSSR-RDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADD 1315
+R+ + R +R+ R + DR+ RE LR +R+ + LR ++ + +R ++
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRK-FREEEQLRQEREEQ--QLRPQQRD-GKYRWEEE 1826
Query: 1316 RKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDE 1374
+ ++EE++ R R E+ +E+ +E+ W+ E+ + R + +E
Sbjct: 1827 QL--QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883
Score = 168 bits (426), Expect = 3e-41
Identities = 208/901 (23%), Positives = 428/901 (47%), Gaps = 121/901 (13%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
QE+ EQ LK ++E + L +R+ E R++RL+ +R ++ L++ E E +
Sbjct: 560 QERREQR-------LKREQEERRDQLLKREE-ERRQQRLKREQEERLEQRLKREEVERLE 611
Query: 604 VRKAEEERLRQEAKERE-KERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
+ E+RL++E E E ++++L+ EQ +++ + R EQ ++ E K ++ + E LE
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLK--REEEEERLE 669
Query: 663 E-LDPDFIMAKQVEQL-EKEKKELQERLKNQEKKIDY-------------FERAKRLEEI 707
+ L + ++ ++L E+E+++ +ER+K++ K + + R ++ E
Sbjct: 670 QRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQ 729
Query: 708 PLIKSAYEEQRIKDMDLWEQQEEERITTMQLERE---------KALEHKNRMSRMLEDRD 758
+ E++R ++ +L + QEEER Q E E +A E R + L R
Sbjct: 730 RRRQEQEEKRRRRESEL-QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 759 LFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRA 818
+R + RQ EE+ ++ + L EE E+R+RQR+E + + E+EE+ QRR
Sbjct: 789 --PLREQRERQLRAEERQQREQRFLPEEEEK--EQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 819 EEQMLKERE-------ERERAERAKREEELREYQERVKK-----------LEEVERKKRQ 860
Q L+E E ER R++ +R+++ R E +K L+E RK++Q
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 861 ------RELEIEERERRR--EEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRG 912
EL+ EERE+RR E+ER+ + +++ R+ E R+ E + ++R+
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE-EREKRRRQERERQYRK- 962
Query: 913 PPEKEWRRGEGR--DEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRR 970
+K+ ++ E + E+ RR +ER ++ ++E+ L+ +++++ R ++R RR
Sbjct: 963 --DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE----LQQEEEQLLR----EEREKRR 1012
Query: 971 GPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWR 1030
E +R R+ + + + ++R RR+ + +R + + + L E+R + R
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR 1072
Query: 1031 TADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPR 1090
+ +R R+ ++ + +E R + +R R + + + + ++R R
Sbjct: 1073 RQELERQYRK-EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKR 1131
Query: 1091 RGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSR 1150
R + +R R + + + L ++ R + +R R E + + + +++ R
Sbjct: 1132 RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKR 1191
Query: 1151 RADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREE--------SWGPPRESRPSEERE 1202
R + +R R ++ + + K++ R+E W P +E+ + +
Sbjct: 1192 RQERERQYREEEELQ-----------RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240
Query: 1203 W--DREKERDRDNQDREENDKDPERE------RDRERDVDREDRFRRPRDEGGWRRGPAE 1254
+ RE E+ R +D + D+ +++ +ERD ++E R + RD R P E
Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD----RHFPEE 1296
Query: 1255 ES---SSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWR 1311
E +++ RRD + +++++ R++R + R R++ D + R L EREE R
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE-TDRKFREEEQLLQEREEQPLRR 1355
Query: 1312 RADDRK--DDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTK 1369
+ DRK ++ + ++ R+ R R ++RER+ KE+ R ++ + LR+ +
Sbjct: 1356 QERDRKFREEELRHQEQGRKF---LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 1370 N 1370
+
Sbjct: 1413 D 1413
Score = 168 bits (425), Expect = 4e-41
Identities = 229/1005 (22%), Positives = 423/1005 (42%), Gaps = 168/1005 (16%)
Query: 514 MPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARR- 572
+P E+ + Q K L+ ++ LQ +E QL +E +R +R
Sbjct: 811 LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR 870
Query: 573 ------QTIEERKERLESL--------NIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
Q EERK R +L +++E++ L++ E ELQ+ + + R QE +
Sbjct: 871 DQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQY 930
Query: 619 REKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEEL----DPDFIMAKQV 674
RE+E++ QE EQ+ +RE E+ ++ E + KD ++ EE +P+ ++
Sbjct: 931 REEEQLQQEEEQL----LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 675 EQLEKEKKELQE------RLKNQEKKIDYFERAKRL------EEIPLIKSAYEEQRIKDM 722
E+ +E++ELQ+ R + ++++ +ER R EE L++ E++R+++
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 723 DLWE------QQEEERITTMQLE--REKALEHKNRMSRMLEDRDLFVMR--------LKA 766
+ QQEEE++ + E R + LE + R L+ + ++R +
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 767 ARQSVYEEKLKQFEERLAEERHN--RLEERKRQRKEERRITYYRE--------------- 809
RQ EE+L+Q EE+L E R +E +RQ +EE + E
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
Query: 810 ----KEEEEQRRAEEQMLKEREERERAERAK--REEELREYQERVKKLE----------- 852
+EEEE ++ EEQ+L+E +E+ R ER + REEE + Q+R ++
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQ 1226
Query: 853 -EVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWG---------DRDSEGTWRKG 902
E E++ R+ ++ + R E+ R+L DS L + S+ +RD E R+
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW 1286
Query: 903 PEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDR-------------EPS 949
+ D R P E++ R E ++ R R+ +E + L ++ + E
Sbjct: 1287 QQRD---RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343
Query: 950 LRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADE----- 1004
L + + P R + DR R EE R +G R +R + + +E
Sbjct: 1344 LLQEREEQPLRRQERDRKFRE--EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401
Query: 1005 -DRGNWRHADDDRPPR------------RGLDEDRGSWRTADEDRGPRRGMDDDRGPRRG 1051
+R D DR R R E+ R + +R R R
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHR 1461
Query: 1052 GADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRR 1111
+E + ++ + R+ D R+ +++++ RR D + + + R+
Sbjct: 1462 KFREEEQLLQEREEQQLHRQERD-----RKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 1112 GLDDDRGPWRNADDDRIPRRGAE---DDRGPWRNMDDDRLSRRADDDRFPRRGDD----S 1164
L++++ R + + + +RG R D DR R + R R
Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Query: 1165 RPGPWRPLVKPGGWREKEKA---------REESWGPPRESRPSEEREWDR------EKER 1209
R +R + +E+E+ R+E R+ R + RE ++ E++
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQL 1636
Query: 1210 DRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRD 1269
R +DR+ +++P+ R R DR R+ R+E + E+ RR +RD
Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ------QLRRQERD 1690
Query: 1270 RDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRR 1329
R R E+ RR RER+ L++++ R L + E R+ +++ R +ER +
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER-YRKI 1749
Query: 1330 VPPPALSRDRERDRDREREGE---KEKASWRAEKDRESLRRTKNE 1371
+ L +RE + R +E + +E+ R E++ + LR +++
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESD 1794
Score = 167 bits (424), Expect = 5e-41
Identities = 208/881 (23%), Positives = 400/881 (45%), Gaps = 112/881 (12%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
Q+ + QL L+ ++E + Q E R++RL+ Q E+ + +RE E ++
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQ--ERREQRLK--REQEERRDWLKREEETER 466
Query: 604 -VRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
++ +++L+++ +E +ER L+ E+ +++ +ER EQ + E + + + ++ E
Sbjct: 467 HEQERRKQQLKRDQEEERRERWLKLEEE-ERREQQERREQQLRREQEERREQRLKRQEEE 525
Query: 663 ELDPDFIMAKQVEQLEKEKKELQERL--KNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
E + ++Q QL +E++E +E+L + +EK+++ R +RL+ EQ +
Sbjct: 526 ERLQQRLRSEQ--QLRREQEERREQLLKREEEKRLEQERREQRLK---------REQEER 574
Query: 721 DMDLWEQQEEERITTMQLEREKALEHKNRMSRM--LEDRDLFVMRLKAARQSVYEEKLKQ 778
L +++EE R ++ E+E+ LE + + + LE + RLK R+ EE+ +Q
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK--REEPEEERRQQ 632
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKRE 838
+ +EE+ R +++ R+ ++ERR R K EEE+ R E+++ +E EE ER E+ E
Sbjct: 633 LLK--SEEQEERRQQQLRREQQERR--EQRLKREEEEERLEQRLKREHEE-ERREQELAE 687
Query: 839 EELREYQERVK-------------------KLEEVERKK--RQRELEIEERERRREEERR 877
EE + +ER+K K+ RK+ ++R E EE+ RRRE E +
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Query: 878 LGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRR-----GPPEKEWRRGEGRDEDRSHR- 931
+ + + + ++ + TW+ E SE R PP +E R + R E+R R
Sbjct: 748 WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQRE 807
Query: 932 -----RDEERPRRLGDDEDREPSLR--PDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADD 984
+EE+ +R +RE L+ +++++ RR +R + EED D
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR----ERAQQLQEEEDGLQE---DQ 860
Query: 985 DRPSWRNTDDDRPPRRIADEDRGNWRHA--------DDDRPPRRGLDEDRGSWRTADEDR 1036
+R + D+ R +E+R RH + R ++ L E+ + E+R
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR--EER 918
Query: 1037 GPRRGMDDDRGPRRGG---------ADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDR 1087
RR + +R R +ER R + +R R+ + + + ++
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEP 978
Query: 1088 GPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDR 1147
RR + ++ R + + + L ++R R + +R R+ E + + + ++R
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 1148 LSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKARE-ESWGPPRESRPSEEREWDRE 1206
RR + R ++ L+ G RE + +E E E EE + RE
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLL--GEERETRRRQELERQYRKEEELQQEEEQLLRE 1096
Query: 1207 KERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRD 1266
+ R Q+RE ++ E + E + RE+R +R R E + EE + R+
Sbjct: 1097 EPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 1267 DRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDP 1326
+ ++RR ++ R RE +L+ + ++ LR E+E+ RR + + R EE
Sbjct: 1157 E---PEKRRRQELERQYREEEELQQEEEQL---LREEQEK----RRQERERQYREEEE-- 1204
Query: 1327 PRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRR 1367
L R + + R R+ E ++ W+ E ++E+ R
Sbjct: 1205 --------LQRQKRKQRYRD-EDQRSDLKWQWEPEKENAVR 1236
Score = 167 bits (423), Expect = 6e-41
Identities = 212/891 (23%), Positives = 395/891 (44%), Gaps = 105/891 (11%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
+E+ + L + + ++E + RR+ E R++RL+ Q E+E L+QR Q+
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR---QEEEERLQQRLRSEQQ 537
Query: 604 VRKAEEERLRQEAKEREKERILQEH-EQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
+R+ +EER Q K E++R+ QE EQ K+ ER +Q+ K E E
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE--------------E 583
Query: 663 ELDPDFIMAKQVEQLEKE-KKELQERLKNQEKKIDYFERAKRLEEI--PLIKSAYEEQRI 719
E + +Q E+LE+ K+E ERL+ +E++ +R + EE L+KS +E+R
Sbjct: 584 ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERR 643
Query: 720 KDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVM---------RLKA---- 766
+ EQQE + E E+ LE + + E R+ + R+K+
Sbjct: 644 QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPK 703
Query: 767 ----------ARQS-VYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQ 815
ARQS VY KQ +R +E+ + R+ + + + +R+++EEEQ
Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763
Query: 816 RR-------AEEQMLKEREE-------RERAERAKREEELREYQER-VKKLEEVERKKRQ 860
RR AEE+ + R+ RE+ ER R EE ++ ++R + + EE E+++RQ
Sbjct: 764 RRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQ 823
Query: 861 RE--------LEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGT----WRKGPEADSE 908
R LE EE+ +RRE ++L + ++ + R E WR E + +
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERK 883
Query: 909 WRRG-----PPEKEWRRGEGR--DEDRSHRRDEERPRRLGDDEDR----EPSLRPDDDRV 957
RR P +E R E + E+ + EER +R +++R E L+ +++++
Sbjct: 884 RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
Query: 958 PRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRP 1017
R ++R RR E +R R+ + + ++ RR + ++ + +
Sbjct: 944 LR----EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
Query: 1018 PRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDR 1077
+ L E+R R + +R R+ D+ + +ER R + +R R + +
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRK-KDELQQEEEQLLREEREKRRLQERERQYREEEELQQ 1058
Query: 1078 GPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDR 1137
+ + ++R RR + +R R+ + + + L ++ R + +R R E +
Sbjct: 1059 EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 1138 GPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRP 1197
+ + ++R RR + R ++ L++ + + + E + E +
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Query: 1198 SEE---REWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAE 1254
EE RE ++ ++R+ Q REE + ++ + R RD D+ R + W+ P +
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ-------RSDLKWQWEPEK 1231
Query: 1255 ESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRAD 1314
E++ + R+ + R+ D + LR+R+ +D + G + ER+ RR
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQ--LRDRQSQQDLQHLLGE--QQERDREQERRRWQ 1287
Query: 1315 DRKDDRVEERDPPRRVPPPALSRDRERDRDRE--REGEKEKASWRAEKDRE 1363
R EE R A RDR+ +++ RE E+E+ R E DR+
Sbjct: 1288 QRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE-EREEKRRRQETDRK 1337
Score = 164 bits (415), Expect = 5e-40
Identities = 225/947 (23%), Positives = 424/947 (44%), Gaps = 150/947 (15%)
Query: 540 AHILQEKEEQHQLAVTAYLKNSRKEHQRI-LARRQTIEERKERLESLNIQREKEELEQRE 598
AH Q++EEQ + + + E R L+ R + E++ER Q EE +QRE
Sbjct: 754 AHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER------QLRAEERQQRE 807
Query: 599 AELQKVRKAEEERLRQEAKEREKE-RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDID 657
+ +E+R RQ +EREKE + L+E EQ+++ RER +Q+++ E G + +D +
Sbjct: 808 QRFLPEEEEKEQRRRQR-REREKELQFLEEEEQLQR---RERAQQLQEEEDGLQ--EDQE 861
Query: 658 IEDLEELDPDFIMAKQVEQLEKEKKE-------LQERLKNQEKKIDYFERAKRLEEIPLI 710
+E D Q+E+ K ++ LQE+L+ +++ + E + EE
Sbjct: 862 RRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKR 921
Query: 711 KSAYEEQRIKDMDLWEQQEEERITT-MQLEREKALEHKNRMSRMLEDRDLFVM------R 763
+ +E++ ++ + +Q+EE+ + + R + E + R + L+ ++ ++ R
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR 981
Query: 764 LKAARQSVY--EEKLKQFEERLA-EERHNRL-----------------------EERKRQ 797
+ R+ Y EE+L+Q EE+L EER R EER+++
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR 1041
Query: 798 RKEERRITYYREKEEEEQRRAEEQML-KEREERERAE---RAKREEELREYQERVKKLEE 853
R +ER Y +EEEE ++ EEQ+L +ERE R R E + ++EEEL++ +E++ + E
Sbjct: 1042 RLQERERQY---REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP 1098
Query: 854 VERKKRQRELEIEERE----------RRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGP 903
+R++++RE + E E R E+RR + ++ ++ E R+ P
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEP 1158
Query: 904 EADSEWRRGPPEKEWRRGEG---------RDEDRSHRRDEERPRRLGD------------ 942
E + RR E+++R E R+E R++ ER R +
Sbjct: 1159 E---KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 943 DEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDD------R 996
DED+ L+ + + D++ +G E ++F R +D + R + D
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF--RQLEDSQLRDRQSQQDLQHLLGE 1273
Query: 997 PPRRIADEDRGNWRHADDDRPPRRGL--DEDRGSWRTADEDRGPRRGMDDDRGPRRGGAD 1054
R +++R W+ D P L +E + + R + + ++ + ++R +R +
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 1055 DERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLD 1114
+R +R + R +++ RR D + + R+ +++++ RR +
Sbjct: 1334 TDR-KFREEEQLLQER----EEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-QE 1387
Query: 1115 DDRGPWRNADDDRIPRRGAE--DDRGPWRNMDDDRLSRRADDDRFPRRGDD-SRPGPWRP 1171
+R + R R + DR ++ +LSR+ D +F R R
Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447
Query: 1172 LVKPGGWREKEKAR----EESWGPPRESRPSEEREWDRE----------KERDRDNQDRE 1217
++ +E+ R EE RE + +E DR+ +ERDR +++E
Sbjct: 1448 FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
Query: 1218 ENDKDPERE-RDRERDVDREDRFRR-PRDEGGWRRGPAEESSSWRDSSRRDDRDRDDR-- 1273
++PER+ + E+ + R+ R R+ ++E RR R RR DRDR R
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR-------QERGQQRRQDRDRKFREE 1560
Query: 1274 ---RRERDDRRDLRERRD----LRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDP 1326
R+ER++++ R+ RD L + + RR R E+ RR + ++ R +ERD
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR-QERDR 1619
Query: 1327 PRRVPPPALSRDRERD---RDREREGEKEKASWRAEKDRESLRRTKN 1370
R L E+ ++R+R+ +E+ R ++ + LR ++
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD 1666
Score = 162 bits (409), Expect = 3e-39
Identities = 193/849 (22%), Positives = 365/849 (42%), Gaps = 137/849 (16%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK--VRKAEEERLRQEA 616
+ R+E +R LA + E++ERLE + QR EEL ++ E Q+ R+AEEE+L Q
Sbjct: 138 RQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL-QSC 196
Query: 617 KEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQ 676
K E E E EQ+++ EL LE + K E+
Sbjct: 197 KGHETEEFPDE-------------EQLRRREL------------LE------LRRKGREE 225
Query: 677 LEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTM 736
+++++E Q+R+ +E++ ++ +R L ++EEE++
Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVL----------------------RKEEEKLQEE 263
Query: 737 QLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEER-- 794
+ +R++ L+ + R LE ++L R + +Q + +Q + EER + EER
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 795 ---KRQRKEERRITYYREKEEE----------EQRRAEEQMLKEREERERAERAKREEEL 841
+R+++EERR R ++EE E+ R E+Q+ +E+EE R ++ +RE++L
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQL 383
Query: 842 REYQE--RVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTW 899
R Q+ R ++L ++ +R+++L E++ RR ++ RR +++ R + +
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 900 RKGPEADSEWRRG--PPEKEWRRGEGRDEDRSHRRDEERPRR-----LGDDEDREPSLRP 952
+ + + E RR E+E R E + +RD+E RR L ++E RE R
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERR 503
Query: 953 DDDRVPRRGMDDDRGPR--RGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWR 1010
+ RR ++ R R R EE+R +R + + R ++R + + E+
Sbjct: 504 EQQL--RREQEERREQRLKRQEEEERLQQRLRSEQQ--LRREQEERREQLLKREEEKRLE 559
Query: 1011 HADDDRPPRRGLDEDRGSWRTADEDRGP---RRGMDDDRGPRRGGADDERSSWRNADDDR 1067
++ +R +E R +E+R +R ++ R + ER + R
Sbjct: 560 QERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 1068 GPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDR 1127
R +++R + +++ RR + RR + R R R +++R
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERR----QQQLRREQQERREQRLK--------REEEEER 667
Query: 1128 IPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREE 1187
+ + RL R +++R + + + RE+ K+R
Sbjct: 668 L----------------EQRLKREHEEERREQELAEE---------EQEQARERIKSRIP 702
Query: 1188 SWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGG 1247
W ES + + R ++ Q R + ++ R R+ E E+R R + E
Sbjct: 703 KWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEE 762
Query: 1248 WRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEV 1307
RR + + S R R R R ++R+ + R + R R++R P E+E+
Sbjct: 763 QRRDFTWQWQAEEKSER--GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820
Query: 1308 SSWRRADDRKDDRVEERDPPRR--------VPPPALSRDRERDRDREREGEKEKASWRAE 1359
RR +++ +EE + +R L D+ER R +E+ + +K W+ E
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD-QKWRWQLE 879
Query: 1360 KDRESLRRT 1368
++R+ R T
Sbjct: 880 EERKRRRHT 888
Score = 127 bits (318), Expect = 1e-28
Identities = 145/619 (23%), Positives = 272/619 (43%), Gaps = 58/619 (9%)
Query: 791 LEERKRQRKEERRITYYREKEEEEQRRAE---EQMLKEREERERAERAKREEELREYQER 847
L+E KR R + + ++EE+QRR E Q+ +E +R R +R ++E EL E +E+
Sbjct: 95 LDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 848 VKKLEEVERKKRQR--------ELEIEERERRREEERRLGDSSLSRKDSRWGD------R 893
+K E +E++ RQR E +ERE RR EE +L S + + D R
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQL-QSCKGHETEEFPDEEQLRRR 213
Query: 894 DSEGTWRKGPEADSEWRR--------GPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDED 945
+ RKG E + RR EKEWR+ E + EE P+R + ++
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 946 REPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADED 1005
E LR + + RR ++ ++ ++ RR +++R + ++ RR E+
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 1006 RGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADD 1065
R ++ RR +E R +++ R ++ RR ++ R +
Sbjct: 334 R-------REQQLRREQEERREQQLRREQEEERR-----EQQLRREQEEERREQQLRREQ 381
Query: 1066 DRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADD 1125
+ L ++ RR R + + + + ++ RR +++R ++ +
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Query: 1126 DRIPR-RGAEDDRGPW--RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKE 1182
R R + +++R W R + +R + + R ++ R W L + RE++
Sbjct: 442 RREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER-REQQ 500
Query: 1183 KAREESWGPPRESRPSEEREWDREKERDRDNQD-REENDKDPERERDRERDVDREDRFRR 1241
+ RE+ RE E+ R++E +R Q R E E+E RE+ + RE+ R
Sbjct: 501 ERREQQL--RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 1242 PRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERR---DLRDDRDRRGP 1298
++ R +E + R ++R + +RE+++R + R +R + + +RR
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR-- 616
Query: 1299 PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDR--EREGEKEKASW 1356
R +REE RR K + EER + L R+++ R++ +RE E+E+
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQ------LRREQQERREQRLKREEEEERLEQ 670
Query: 1357 RAEKDRESLRRTKNETDED 1375
R +++ E RR + +E+
Sbjct: 671 RLKREHEEERREQELAEEE 689
Score = 114 bits (286), Expect = 5e-25
Identities = 101/346 (29%), Positives = 183/346 (52%), Gaps = 37/346 (10%)
Query: 558 LKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEA- 616
L+ R+E Q L+R++ +RK RLE ++R+++E + E E Q R+ +++LRQE
Sbjct: 1563 LRQEREEQQ--LSRQE--RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 617 -KEREKERILQE------HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFI 669
K RE E++LQE H Q + + E Q+++ E + D D + EE
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE------ 1672
Query: 670 MAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQE 729
EQL +E +E Q R + +++K E+ R +E K EEQ+++ +L +
Sbjct: 1673 -----EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER-KFLQEEQQLRRQELERKFR 1726
Query: 730 EERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN 789
EE + E+E+ L + R ++LE+ L R + + ++ + EE+L +ER
Sbjct: 1727 EEEQLRQETEQEQ-LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 790 ---RLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846
R +E R+ +EE ++ R++ EE+Q R +++ K R E E+ + ++E+ LR+ ++
Sbjct: 1786 QQLRSQESDRKFREEEQL---RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Query: 847 RVKKLEE---VERKKRQRELEI---EERERRREEERRLGDSSLSRK 886
R + EE + K R+ E E+ EE++RR+E ER+L + + R+
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888
Score = 88.6 bits (218), Expect = 4e-17
Identities = 112/483 (23%), Positives = 209/483 (43%), Gaps = 49/483 (10%)
Query: 912 GPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRG 971
G E++ R +G++ RR EE RR + DR+ P R +R + +R G
Sbjct: 94 GLDEEKRARCDGKESLLQDRRQEEDQRRF-EPRDRQLEEEPGQRRRQKR-QEQERELAEG 151
Query: 972 PEEDRFSRRGADDDRPS-----WRNTDD--DRPPRRIADEDRGNWRHADDDRPPRRGLDE 1024
E+ R DR WR + +R RR +E + + + + P DE
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP----DE 207
Query: 1025 DRGSWRTADEDRGPRRGMDDDRGPRRGGAD-----DERSSWRNADDD-RGPRRGLDDDRG 1078
++ R E R R+G ++ + RR D +E WR + R L ++
Sbjct: 208 EQLRRRELLELR--RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 1079 PR-RGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDR 1137
R R + ++ R ++ R ++++ +R L ++ R +++R ++ ++
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQR-LRREQQLRRKQEEERREQQEERREQ 324
Query: 1138 GPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRP 1197
R ++R ++ ++ RR R RE+E+ R E +
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLR-------------REQEEERREQQLRREQEEE 371
Query: 1198 SEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRP---RDEGGWRRGPAE 1254
E++ RE++ R+ Q R E E++ RE+ + RE + RR R E RR E
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 1255 ESSSWRDSSRRDDRDRDDR-RRERDDRRD--LRERRDLRDDRDRRGPPLRSEREEVSSWR 1311
E R + + R+ R +RE+++RRD RE R +++RR L+ ++EE R
Sbjct: 432 E----RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 1312 RADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNE 1371
+++R E+++ RR ++ R++ +R+ E+E+ R +++ LRR + E
Sbjct: 488 WLKLEEEERREQQE--RREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ-LRREQEE 544
Query: 1372 TDE 1374
E
Sbjct: 545 RRE 547
Score = 62.0 bits (149), Expect = 4e-09
Identities = 61/295 (20%), Positives = 129/295 (43%), Gaps = 46/295 (15%)
Query: 1108 GPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPW----RNMDDD----RLSRRADDDRFPR 1159
G GLD+++ + + + R E+D+ + R ++++ R +R + +R
Sbjct: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
Query: 1160 RGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREEN 1219
G++ R R++++ EE W R+ + +ERE R +E + E
Sbjct: 150 EGEEQSEKQERL-----EQRDRQRRDEELW---RQRQEWQEREERRAEEEQLQSCKGHET 201
Query: 1220 DKDPERERDRERDV----------------DREDRFRRPRDEGGWRRGPAEESSSWRDSS 1263
++ P+ E+ R R++ +R+DR + +E WR+ E+ ++
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK---RETVLRKEEE 258
Query: 1264 RRDDRDRDDRRRERDDRRDLR--ERRDLRDDRD---------RRGPPLRSEREEVSSWRR 1312
+ + + +R +++ LR ER++LR +R RR LR ++EE ++
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 1313 ADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRR 1367
+ R+ E+ RR ++ R++ RE E+E+ + +++E RR
Sbjct: 319 EERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERR 373
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 144 bits (364), Expect = 4e-34
Identities = 137/500 (27%), Positives = 223/500 (44%), Gaps = 66/500 (13%)
Query: 863 LEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGE 922
L+ R +E R + KD+ DR E +K E E R+ E + +R
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDR--ERNRQKERERRREKRQTERETDRKRER 81
Query: 923 GRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGA 982
R++DR +RD R R+ D ++E + D +R +R + +R R E +R RG
Sbjct: 82 RREKDRHRKRDRHRERQR--DREKERERQTDRERDRQREKERNRQKERERETEREGERGR 139
Query: 983 DDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGM 1042
D R TD R R D ++ R D +R +R + +R R +++R RR
Sbjct: 140 D------RQTDGQRERERQRDAEKERERQTDRER--QRQTERNRQKEREREKNRQERRER 191
Query: 1043 DDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRG 1102
+ R N +DR RG + +R + +R +R
Sbjct: 192 ERQREKE------------NKTEDRHSERGRERERERETETETER------------KRQ 227
Query: 1103 MDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGD 1162
D +R +R + +R + A+ +R R E D+ R D DR DR R+ +
Sbjct: 228 TDRERDRQRKTERERE--KQAERERASERETERDKERERERDRDR-------DRDRRQKE 278
Query: 1163 DSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKD 1222
R + + RE E+ RE RE + +RE +RE+ER+R+ Q E D++
Sbjct: 279 RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDRE 338
Query: 1223 PERERDRER--DVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDR 1280
ERER R+R ++DRE R R+ EG RR E R+ R+ R+R++R R+RD
Sbjct: 339 KERERKRKRQTEMDRE-RNRQTGREG--RRQAERERERERERDRQSAREREERERDRD-- 393
Query: 1281 RDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
RD ++ R+ + ++DR G +RE R DR+ +R ER R+++
Sbjct: 394 RDRQKERERQTEKDRDG-----QRETEKQREREKDRESERGRER---------GREREKQ 439
Query: 1341 RDRDREREGEKEKASWRAEK 1360
+ R+R+RE + ++ + R K
Sbjct: 440 KGRERDRERQTDRQAGRQRK 459
Score = 138 bits (348), Expect = 3e-32
Identities = 130/481 (27%), Positives = 228/481 (47%), Gaps = 44/481 (9%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
+N +KE +R +RQT E + E +REK+ +R+ ++ R E+ER RQ +E
Sbjct: 56 RNRQKERERRREKRQTERETDRKRER---RREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 619 REKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVE-QL 677
R+++R E E+ ++K E+ ++TE + +D + E + K+ E Q
Sbjct: 113 RDRQR---EKERNRQK------ERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163
Query: 678 EKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQ 737
++E++ ER + +E++ + + +R E K E R + ++E ER T +
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG--RERERERETETE 221
Query: 738 LEREKALEHKNRMSRMLE-DRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKR 796
ER++ + + R E +R+ R +A+ + +K ++ E +R R +ER+R
Sbjct: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
Query: 797 Q--RKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEV 854
Q RK +RR RE E + +R+ E ERER KRE E +ER ++ E
Sbjct: 282 QTDRKRQRRTERDRETERKRERQRER-------ERERERNRKRERE----RERERERERQ 330
Query: 855 ERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPP 914
+R RE +ERER+R+ + + D +R+ R G R +E + E D + R
Sbjct: 331 RETERDRE---KERERKRKRQTEM-DRERNRQTGREGRRQAERERERERERDRQSARERE 386
Query: 915 EKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEE 974
E+E R R ++R + +++R + ++ RE + +R RG +R ++G E
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGR--EREKQKGRER 444
Query: 975 DRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADE 1034
DR + R R+T PP R A R +D +R P RG+ W+++ E
Sbjct: 445 DRERQTDRQAGRQRKRSTLYVNPPPRTA---RSGVVQSDPNR-PTRGI-----RWKSSPE 495
Query: 1035 D 1035
D
Sbjct: 496 D 496
Score = 138 bits (347), Expect = 4e-32
Identities = 142/539 (26%), Positives = 247/539 (45%), Gaps = 49/539 (9%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
+E+E + + T + ++E +R R + + +ER QR++E+ +R+ + ++
Sbjct: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHRER------QRDREKERERQTDRER 113
Query: 604 VRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEE 663
R+ E+ER RQ+ +ERE ER E E+ + + + E+ ++ + + + D E +
Sbjct: 114 DRQREKERNRQKERERETER---EGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ 170
Query: 664 LDPDFIMAKQVEQLEKEKKELQERLKNQEKKID--YFERAKRLEEIPLIKSAYEEQRIKD 721
+ + ++ E+ +E++E +ER + +E K + + ER + E ++ E +R D
Sbjct: 171 TERNRQKEREREKNRQERRE-RERQREKENKTEDRHSERGRERERERETETETERKRQTD 229
Query: 722 MDLWEQQEEERITTMQLEREKALEHKNRMSRMLE---DRDLFVMRLKAARQSVYEEKLKQ 778
+ Q++ ER Q ERE+A E + + E DRD R + R+ + K ++
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE-ERERAERAKR 837
ER E R ER+R+R+ ER RE+E E +R E Q ER+ E+ER + KR
Sbjct: 290 RTERDRETERKR--ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 838 EEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEG 897
+ E+ +R + + +RQ E ERER RE +R+ R+ R DRD +
Sbjct: 348 QTEM----DRERNRQTGREGRRQAE---RERERERERDRQSAREREERERDR--DRDRQK 398
Query: 898 TWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRV 957
+ E D + +R EK+ R + R+ +R R ER ++ G + DRE R D +
Sbjct: 399 ERERQTEKDRDGQR-ETEKQREREKDRESERGRERGREREKQKGRERDRE---RQTDRQA 454
Query: 958 PRRGMDDDRGPRRGPEEDRFSRRGADDDRPS----WRNTDDDRPPRRIADEDRGNWRHAD 1013
R+ P R +D +RP+ W+++ +D P+ A R W
Sbjct: 455 GRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPED--PK--AASTRFPW---- 506
Query: 1014 DDRPPR--RGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPR 1070
RP + RG R W + G +RG + GG E + GPR
Sbjct: 507 -GRPAKASRGRVAGRRRW---EPRLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPR 561
Score = 137 bits (346), Expect = 5e-32
Identities = 131/454 (28%), Positives = 201/454 (44%), Gaps = 51/454 (11%)
Query: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLE 852
ER RQ++ ERR REK + E+ E K RE+ KR+ ++R K+ E
Sbjct: 55 ERNRQKERERR----REKRQTER----ETDRKRERRREKDRHRKRDRHRERQRDREKERE 106
Query: 853 EVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRG 912
++R R+ E +ER R++E ER R+ R DR ++G + + D+E R
Sbjct: 107 RQTDRERDRQRE-KERNRQKERER-----ETEREGERGRDRQTDGQRERERQRDAEKER- 159
Query: 913 PPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPD---DDRVPRRGMDDDRGPR 969
E++ R R +R+ +++ ER + + +RE + +DR RG + +R
Sbjct: 160 --ERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER--E 215
Query: 970 RGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSW 1029
R E + +R D +R R T+ +R + A+ +R + R + D+ R D DR
Sbjct: 216 RETETETERKRQTDRERDRQRKTERER--EKQAERERASERETERDKERERERDRDRDRD 273
Query: 1030 RTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGP 1089
R E R D + RR D E R +R R + R R + +R
Sbjct: 274 RRQKE----RERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERER 329
Query: 1090 RRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLS 1149
+R + DR R +R +R + DR RN R RR AE +R R + DR S
Sbjct: 330 QRETERDREKER----ERKRKRQTEMDRE--RNRQTGREGRRQAERERE--RERERDRQS 381
Query: 1150 RRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKER 1209
R ++R R D + +E+E+ E+ RE+ ERE DRE ER
Sbjct: 382 AREREERERDRDRDRQ-------------KERERQTEKDRDGQRETEKQREREKDRESER 428
Query: 1210 DRDNQDREENDKDPERERDRERDVDREDRFRRPR 1243
R+ E +K RERDRER DR+ +R R
Sbjct: 429 GRER--GREREKQKGRERDRERQTDRQAGRQRKR 460
Score = 132 bits (333), Expect = 2e-30
Identities = 126/438 (28%), Positives = 194/438 (44%), Gaps = 59/438 (13%)
Query: 951 RPDDDRVPRR---------GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRI 1001
RP PRR DDR R E +R RR + R + R TD R RR
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERER--RR---EKRQTERETDRKRERRRE 84
Query: 1002 ADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWR 1061
D R RH + R R + +R + R D R R +R R + ER R
Sbjct: 85 KDRHRKRDRHRERQRD--REKERERQTDRERDRQREKERNRQKER-ERETEREGERGRDR 141
Query: 1062 NADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWR 1121
D R R D ++ R D +R +R + +R R + +R RR + R
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRER--QRQTERNRQKEREREKNRQERRERERQREK-E 198
Query: 1122 NADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREK 1181
N +DR RG E +R + +R R+ D +R +R + RE+
Sbjct: 199 NKTEDRHSERGRERERERETETETER-KRQTDRERDRQRKTE---------------RER 242
Query: 1182 EKAREESWGPPRESRPSEEREWDREKERDRDNQDRE-ENDKDPERERDRERDVDREDRFR 1240
EK E RE+ +ERE +R+++RDRD + +E E D +R+R ERD + E +
Sbjct: 243 EKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE 302
Query: 1241 RPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR---RERDDRRDLRERRDLRDDRDRRG 1297
R R+ R E + R+ R +R+R+ +R R+R+ R+ + +R DR+R
Sbjct: 303 RQRE-----RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRER-- 355
Query: 1298 PPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
R+ RR +R+ +R ERD R+ R+R+RDRDR++E E++
Sbjct: 356 -----NRQTGREGRRQAERERERERERD--RQSAREREERERDRDRDRQKERERQ----- 403
Query: 1358 AEKDRESLRRTKNETDED 1375
EKDR+ R T+ + + +
Sbjct: 404 TEKDRDGQRETEKQRERE 421
Score = 125 bits (314), Expect = 3e-28
Identities = 129/483 (26%), Positives = 201/483 (41%), Gaps = 73/483 (15%)
Query: 811 EEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERER 870
+E +RR Q K+ + +R ++E E R + + ++ E +RK R+R E ++R R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTER--ETDRK-RERRRE-KDRHR 89
Query: 871 RRE---EERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDED 927
+R+ E +R + R+ R DR E + E + E E+E RG R D
Sbjct: 90 KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE-----TEREGERGRDRQTD 144
Query: 928 ----RSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPE---------E 974
R +RD E+ R DRE + + +R R + +R RR E E
Sbjct: 145 GQRERERQRDAEKERE--RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTE 202
Query: 975 DRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADE 1034
DR S RG + +R R T+ + +R D +R R + +R + + +R S R +
Sbjct: 203 DRHSERGRERERE--RETETETERKRQTDRERDRQRKTERER--EKQAERERASERETER 258
Query: 1035 DRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMD 1094
D+ R D DR D R R DR +R + DR R + R R +
Sbjct: 259 DKERERERDRDRD------RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312
Query: 1095 DDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADD 1154
+R R + +R R + +R R + +R +R E DR RN R RR +
Sbjct: 313 RNRKRERERERERERERQRETERD--REKERERKRKRQTEMDRE--RNRQTGREGRRQAE 368
Query: 1155 DRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQ 1214
RE+E+ RE RE R ER+ DR+++++R+ Q
Sbjct: 369 ------------------------RERERERERDRQSARE-REERERDRDRDRQKERERQ 403
Query: 1215 DREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274
++ D E E+ RER+ DRE E G RG E R+ R DR R
Sbjct: 404 TEKDRDGQRETEKQREREKDRE-------SERGRERGREREKQKGRERDRERQTDRQAGR 456
Query: 1275 RER 1277
+ +
Sbjct: 457 QRK 459
Score = 118 bits (295), Expect = 4e-26
Identities = 120/490 (24%), Positives = 197/490 (40%), Gaps = 44/490 (8%)
Query: 739 EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLE---ERK 795
ER + E + R + +R+ R + + + ++ + E + E+ + ER
Sbjct: 55 ERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 796 RQRKEERRITYYREKE-EEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEV 854
RQR++ER RE+E E E R ++ + ERER A++E E + +ER ++ E
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 855 ERKKRQREL---EIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEW-- 909
+K+R+RE E ERER+RE+E + D R R +R++E + + D E
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 910 -----RRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDD 964
R + E R R+ +R R+ ER R D DR D R R
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDR----DRDR-------DRRQKERERQT 283
Query: 965 DRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDE 1024
DR +R E DR + R + R R + +R R + +R R + +R + +
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERER 343
Query: 1025 DRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGP--RRG 1082
R D +R + G + R R + ++A + R D DR R
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
Query: 1083 MDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRR--GAEDDRGPW 1140
+ DR +R + R + + +RG RG + ++ R D +R R G + R
Sbjct: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
Query: 1141 RNMDDDRLSRRA---DDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRES-- 1195
R +R D P RG + P P K + WG P ++
Sbjct: 464 YVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDP---------KAASTRFPWGRPAKASR 514
Query: 1196 -RPSEEREWD 1204
R + R W+
Sbjct: 515 GRVAGRRRWE 524
Score = 99.4 bits (246), Expect = 2e-20
Identities = 95/343 (27%), Positives = 149/343 (43%), Gaps = 46/343 (13%)
Query: 1066 DRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRG-LDDDRGPWRNAD 1124
D RR + RRG+ G D +R ++ + R R+ + DR R +
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 1125 DDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKA 1184
DR +R +R R + +R + R D + + + + RE+E
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKE------------RERETE 132
Query: 1185 REESWGPPRESRPSEEREWDR--EKERDRDNQDREENDKDPERERDRERDVDREDRFRRP 1242
RE G R++ ERE R EKER+R + + R+++RER+ +R++R R
Sbjct: 133 REGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERE 192
Query: 1243 R------------DEGGWRRGPAEESSSWRDSSRRDDRDRDDRRR--------------- 1275
R E G R E+ + + R+ DR+RD +R+
Sbjct: 193 RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252
Query: 1276 ERDDRRDL-RER-RDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPP 1333
ER+ RD RER RD DRDRR + + R DR+ +R ER R
Sbjct: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERE-RER 311
Query: 1334 ALSRDRERDRDREREGEKEKASWR-AEKDRESLRRTKNETDED 1375
+R RER+R+RERE E+++ + R EK+RE R+ + E D +
Sbjct: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Score = 97.4 bits (241), Expect = 8e-20
Identities = 84/296 (28%), Positives = 143/296 (48%), Gaps = 28/296 (9%)
Query: 1096 DRGPRRGMDDDRGPRRGLDDDRGPWRNAD-DDRIPRRGAEDDRGPWRNMDDDRLSRRADD 1154
D RR + RRGL ++AD DDR R E +R + R + R D
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAH---KDADGDDRERNRQKERER-----RREKRQTERETD 76
Query: 1155 DRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQ 1214
+ RR + R K RE+++ RE+ RE + ER+ REKER+R +
Sbjct: 77 RKRERRREKDRHR------KRDRHRERQRDREKE----RERQTDRERDRQREKERNRQKE 126
Query: 1215 DREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274
E +++ ER RDR+ D RE +R ++ R+ E + +R+ +R+R+ R
Sbjct: 127 RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQ-TERNRQKEREREKNR 185
Query: 1275 RERDDRRDLRERRDLRDDR-DRRGPPLRSERE---EVSSWRRADDRKD-DRVEERDPPRR 1329
+ER +R RE+ + +DR RG ERE E R+ D +D R ER+ ++
Sbjct: 186 QERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245
Query: 1330 VPPPALSR---DRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWTTVRR 1382
S +R+++R+RER+ ++++ + E++R++ R+ + T+ D T +R
Sbjct: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
Score = 70.1 bits (170), Expect = 1e-11
Identities = 97/423 (22%), Positives = 175/423 (41%), Gaps = 100/423 (23%)
Query: 541 HILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE 600
H + +E + + + R+ + +R+T ER++ Q E+E +RE E
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREK-------QAERERASERETE 257
Query: 601 LQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
K R+ E +R R + R+KER Q + +++T R+R + K+
Sbjct: 258 RDKERERERDRDR-DRDRRQKERERQTDRKRQRRTERDRETERKR--------------- 301
Query: 661 LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
E++++ +ER +N+++ E +R +
Sbjct: 302 -----------------ERQRERERERERNRKR---------------------ERERER 323
Query: 721 DMDLWEQQEEERITTMQLEREKALEHK-NRMSRMLEDRDLFVMRLKAARQSVYEEKLKQF 779
+ + Q+E ER +REK E K R + M +R+ RQ+ E + +
Sbjct: 324 ERERERQRETER------DREKERERKRKRQTEMDRERN---------RQTGREGRRQAE 368
Query: 780 EERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREE 839
ER E +R R+R+ +E R R++++E +R+ E+ +RE ++ ER K E
Sbjct: 369 RERERERERDRQSAREREERERDR---DRDRQKERERQTEKDRDGQRETEKQREREKDRE 425
Query: 840 ELREYQERVKKLEEVERKKRQRELEIEE---RERRR-----EEERRLGDSSLSRKDSRWG 891
R +ER ++ E+ + ++R RE + + R+R+R R S + + D
Sbjct: 426 SERG-RERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDP--- 481
Query: 892 DRDSEG-TWRKGPE----ADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDR 946
+R + G W+ PE A + + G P K R GR R +R E R
Sbjct: 482 NRPTRGIRWKSSPEDPKAASTRFPWGRPAKASR---GRVAGRRRWEPRLGEKRGQGGEGR 538
Query: 947 EPS 949
PS
Sbjct: 539 RPS 541
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 140 bits (354), Expect = 6e-33
Identities = 187/827 (22%), Positives = 322/827 (38%), Gaps = 125/827 (15%)
Query: 571 RRQTIEERKERLESLNIQREKEELEQREAELQKVRK--AEEERLRQEAKEREKERILQEH 628
+RQ I+ +LE N+++ +E + ++E + VR + LR+ +K +++ +
Sbjct: 169 KRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSS 228
Query: 629 EQIKKKTVRER-----LEQIKKTELGAKAFKDIDIEDLEELDP-DFIMAKQVEQLEKEKK 682
KK L+Q + ++ K P D + K+ ++ K K
Sbjct: 229 SASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKD 288
Query: 683 ELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREK 742
++E+ ++ + + FER + + P S + + +++Q R
Sbjct: 289 RIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQ--RHS 346
Query: 743 ALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEER 802
+ R R L L+ + L + + + RH + +E+
Sbjct: 347 PSPRRKRTPSPSYQRTL-TPPLRRSASPYPSHSLSSPQRKQSPPRH------RSPMREKG 399
Query: 803 RITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRE 862
R + R + ++R + + + +RE+ R +RE E + R + + R R R
Sbjct: 400 RHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRR 459
Query: 863 LEIEERERRR-------EEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPE 915
+ R+RR + R + D S K+SR RDS T D E R +
Sbjct: 460 DARDTRDRRELRDSRDMRDSREMRDYSRDTKESR-DPRDSRSTRDAHDYRDREGRDTHRK 518
Query: 916 KEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEED 975
++ E R R+H R+E + ++ E +DR+ G R P +
Sbjct: 519 EDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRM---GRSRGRVPELPEKGS 575
Query: 976 RFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADED 1035
R SR D S N D +W E R S+ + D
Sbjct: 576 RGSRGSQIDSHSSNSNYHD-------------SW--------------ETRSSY--PERD 606
Query: 1036 RGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDD 1095
R P R D+R R + + R R+ D+R + D+ P + D
Sbjct: 607 RYPER---DNRDQARDSSFERRHGERDRRDNR------ERDQRPSSPIRHQGRNDELERD 657
Query: 1096 DRGPRRGMD--DDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRAD 1153
+R R +D DDR R + DR R+ + +R R + +R R ++ +R R
Sbjct: 658 ERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERER 717
Query: 1154 DDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDN 1213
+ REKE+ RE + ERE DREKER+R+
Sbjct: 718 E------------------------REKERDRERDRDRDHDRERERERERDREKERERE- 752
Query: 1214 QDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDR 1273
REE +++ ERER+RER+ +RE R RD+ E W D D+ RDDR
Sbjct: 753 --REERERERERERERERERERERERARERDK------ERERQRDWEDK----DKGRDDR 800
Query: 1274 RRERDDRRDLRERRDLRDDR-------------DRRGPPLRSEREEVSSWRRADDRKDDR 1320
R +R++ R+ R RD D+R R+ P R E S + D K+++
Sbjct: 801 REKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEK 860
Query: 1321 ------VEERDPPRRVPPPALSRDRE-RDRDREREGEKEKASWRAEK 1360
V R + P L+ DR+ R ++ +R+ E++++S R E+
Sbjct: 861 HRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEE 907
Score = 136 bits (342), Expect = 2e-31
Identities = 198/848 (23%), Positives = 321/848 (37%), Gaps = 88/848 (10%)
Query: 566 QRILARRQTIE----ERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREK 621
+R+ +RQ ++ +R S +++E RE E K+ K +E E E
Sbjct: 87 ERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWET 146
Query: 622 ERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEK 681
R ++ I V E ++K+ ++ + K ++ E++E+ + I + ++ + K
Sbjct: 147 NRDDSDNGDINYDYVHELSLEMKRQKIQRELMK-LEQENMEKREEIIIKKEVSPEVVRSK 205
Query: 682 KELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLERE 741
L+ K + + + P SA ++ R +++R + ++
Sbjct: 206 LSPSPSLRKSSK-------SPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKK 258
Query: 742 KALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEE 801
K + + ED A Y+EK K +R+EE+ R K+
Sbjct: 259 KGPRTPSPPPPIPED---------IALGKKYKEKYKV---------KDRIEEKTRDGKDR 300
Query: 802 RRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQR 861
R + E + ++R + + + ++ + +++ R+KR
Sbjct: 301 GR-----DFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTP 355
Query: 862 ELEIEER--ERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
+ R SLS + R+ D E + R
Sbjct: 356 SPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHE---RTSQSHDR 412
Query: 920 RGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPD--DDRVPRRGMDD-DRGPRRGPEEDR 976
R E R++ R +RD E+ R + +++ S D DDR PR G D D R E R
Sbjct: 413 RHERREDTRG-KRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELR 471
Query: 977 FSR--RGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADE 1034
SR R + + R R+T + R PR D + R A D R R G D R +E
Sbjct: 472 DSRDMRDSREMRDYSRDTKESRDPR-----DSRSTRDAHDYRD-REGRDTHRKEDTYPEE 525
Query: 1035 DRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMD 1094
R R + R ++ R+ R+ + R R G R P RG R
Sbjct: 526 SRSYGRNHLREESSRTEIRNESRNESRS--EIRNDRMGRSRGRVPELPEKGSRGSRGSQI 583
Query: 1095 DDRGPRRGMDDDRGPRRGLDD-DRGPWRN----ADDDRIPRRGAEDDRGPWRNMD----- 1144
D D R + DR P R+ A D RR E DR R D
Sbjct: 584 DSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSS 643
Query: 1145 -------DDRLSR-RADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESR 1196
+D L R ++R R DD R R R++E+ R+ RE
Sbjct: 644 PIRHQGRNDELERDERREERRVDRVDDRRDERARE-------RDRERERDRERERERERE 696
Query: 1197 PSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEES 1256
ERE +RE ER+R + E +K+ +RERDR+RD DRE R RD R EE
Sbjct: 697 RDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREER 756
Query: 1257 SSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDR 1316
R+ R +R+R+ R +R RER+ +D+D+ R +REE+ R D
Sbjct: 757 ERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDG 816
Query: 1317 KDDRVEER-----DPPRRVPPPALSRDRERDRDREREG----EKEKASWRAEKDRESLRR 1367
D+R ++ P P R+ D D G EK + + + +ES
Sbjct: 817 HDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSL 876
Query: 1368 TKNETDED 1375
+ + ED
Sbjct: 877 SPSHLTED 884
Score = 127 bits (318), Expect = 1e-28
Identities = 175/757 (23%), Positives = 299/757 (39%), Gaps = 97/757 (12%)
Query: 678 EKEKKELQERLKNQEKKIDYFERAKRLEEI--PLIKSAYEEQRIKDMDL------WEQQE 729
E+ +L+ER+KN+ + +D + + EE P+ K + + + D+ + E
Sbjct: 79 ERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESE 138
Query: 730 EERIT---------------------TMQLEREKALEHKNRMSRM-LEDRDLFVMRLKAA 767
EE + +++++R+K ++ + +E R+ +++ + +
Sbjct: 139 EENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVS 198
Query: 768 RQSVYEEKLKQFEERLAEERHNRLEERKRQR--KEERRITYYREKEEEEQRRAEEQMLKE 825
+ V + R + + R K K++R+ + ++QR ++ K+
Sbjct: 199 PEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKK 258
Query: 826 REERERAERAKREEEL---REYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSS 882
+ R + E++ ++Y+E+ K + +E K R + ++R R+ ER+
Sbjct: 259 KGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTR------DGKDRGRDFERQREKRD 312
Query: 883 LSRKDSRWGDRDSEGTWR---KGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRR 939
R S G S + R ++ S +R P +R R+
Sbjct: 313 KPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRT---------- 362
Query: 940 LGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPR 999
P LR P + + + P R D + D R R
Sbjct: 363 ------LTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHER 416
Query: 1000 RIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADD-ERS 1058
R ED R + D R ++D+ S R +DR PR G D RR D +R
Sbjct: 417 R---EDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRD-----RRDARDTRDRR 468
Query: 1059 SWRNADDDRGPRRGLDDDRGPRRGMD--DDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDD 1116
R++ D R R D R + D D R R D R G D R ++
Sbjct: 469 ELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDA--HDYRDREGRDTHRKEDTYPEES 526
Query: 1117 RGPWRN-----ADDDRIPRRGAEDDRGPWRNMDDDRLSR-RADDDRFPRRGDDSRPGPWR 1170
R RN + I + R RN DR+ R R P +G G
Sbjct: 527 RSYGRNHLREESSRTEIRNESRNESRSEIRN---DRMGRSRGRVPELPEKGSRGSRGSQI 583
Query: 1171 PLVKPGG-----WREKEKAREESWGPPRESRP-SEEREWDREK-ERDR-DNQDREENDKD 1222
W + E P R++R + + ++R ERDR DN++R++
Sbjct: 584 DSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSS 643
Query: 1223 PERERDRERDVDREDRFRRPR-DEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRR 1281
P R + R +++R++R R D RR +E + RD R DR+R+ R RER+ R
Sbjct: 644 PIRHQGRNDELERDERREERRVDRVDDRR---DERARERDRERERDRERE-RERERERDR 699
Query: 1282 DLRERRDLRDDRDR-RGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
+ + R+L +R R R ER+ R DR+ +R ERD + R+RE
Sbjct: 700 EREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERE 759
Query: 1341 RDRDREREGEKEKASWRA-EKDRESLRRTKNETDEDG 1376
R+R+RERE E+E+ RA E+D+E R+ E + G
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKG 796
Score = 105 bits (261), Expect = 4e-22
Identities = 144/615 (23%), Positives = 255/615 (41%), Gaps = 99/615 (16%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
+ + + H R RR+ +++R + +RE E+ + + + R+ + R R++A++
Sbjct: 404 ERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARD 463
Query: 619 REKERILQEHEQIK---------KKTVRERLEQIKKTELGAKAFKDIDIEDL---EELDP 666
R L++ ++ + T R + ++ A ++D + D E+ P
Sbjct: 464 TRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYP 523
Query: 667 DFIMAKQVEQLEKE--KKELQERLKNQ---EKKIDYFERAK-RLEEIP------------ 708
+ + L +E + E++ +N+ E + D R++ R+ E+P
Sbjct: 524 EESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQI 583
Query: 709 -------------LIKSAY-EEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRML 754
+S+Y E R + D +Q + ER++ R +R
Sbjct: 584 DSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDR------RDNRER 637
Query: 755 EDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEE 814
+ R +R + + E+ ++ EER + +R +ER R+R ER RE+E E
Sbjct: 638 DQRPSSPIRHQGRNDEL--ERDERREERRVDRVDDRRDERARERDRERERDRERERERER 695
Query: 815 QRRAEEQMLKERE-ERERAERAKREEELREYQERVKKLEEVERKKRQRELEIE-ERERRR 872
+R E + KERE ERERA +RE E +ER + + ++R+RE + E ERER R
Sbjct: 696 ERDRERE--KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERER 753
Query: 873 EEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRR 932
EE R R+ R +R+ E + E D E R +++W ED+ R
Sbjct: 754 EERER------ERERERERERERERERERARERDKERER---QRDW-------EDKDKGR 797
Query: 933 DEERPRRLGDDEDREPSLRPDDDRVPRRGMDD-DRGPRRGPEEDRFSRRGADDDRPSWRN 991
D+ R +R EDR P D+ + +R ++ PR+ P+ RR D ++ +
Sbjct: 798 DDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKR----RREHSPDSDAYNS 853
Query: 992 TDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDR-GSWRTADEDRGP------RRGMDD 1044
DD R+ + R + L EDR G W+ +EDR P RR +
Sbjct: 854 GDDKNEKHRLLSQ---VVRPQESRSLSPSHLTEDRQGRWK--EEDRKPERKESSRRYEEQ 908
Query: 1045 DRGPRRGGADDER-------SSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDR 1097
+ + D +R SS A D G + D + R D ++ +
Sbjct: 909 ELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRA---HDENKKKAKIQKK 965
Query: 1098 GPRRGMDDDRGPRRG 1112
++ +DD G RG
Sbjct: 966 PIKKKKEDDVGIERG 980
Score = 94.7 bits (234), Expect = 5e-19
Identities = 175/823 (21%), Positives = 326/823 (39%), Gaps = 141/823 (17%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
++ +E +R L R + E +ER + + +R+++ RE E ++ R E+ER R E +E
Sbjct: 697 RDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERER-EREE 755
Query: 619 REKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDID--IEDLEELDPDFIMAKQVEQ 676
RE+ER + + +++ RER + K + ++D D +D E + +
Sbjct: 756 RERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRD 815
Query: 677 LEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTM 736
E+K ++R +N+ +R E P D D + +++
Sbjct: 816 GHDERKS-KKRYRNEGSPSPRQSPKRRREHSP------------DSDAYNSGDDKN---- 858
Query: 737 QLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEK---------LKQFEERLAEER 787
E+ + L +++ R E R L L RQ ++E+ +++EE+ +E+
Sbjct: 859 --EKHRLL---SQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEK 913
Query: 788 HNRLEERKRQRK--EERR------ITYYREKEEEEQRRAEEQMLKEREERERAERAKREE 839
+ +++++ Q + E R I +++ ++ E RA ++ K+ + +++ + K+E+
Sbjct: 914 VSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKED 973
Query: 840 ELREYQERVKKLEE----VERKKRQRELEIEERERRREEERRLGDSSLSRKD-SRWGDRD 894
++ + ++ E KK Q++ IE++ ++ + + + D +++ + G R
Sbjct: 974 DVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRT 1033
Query: 895 SEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRR--LGDDEDREPSLRP 952
T ++ + G E ++ + D S DE+ P R + + E + P
Sbjct: 1034 PPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWS---DEDVPDRTEVTEAEHTATATTP 1090
Query: 953 DDDRVPRRGMDDDRGP---------------RRGPEEDRFSRRG---------ADDDRPS 988
P + P FS + +
Sbjct: 1091 GSTPSPLSSLLPPPPPVATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNT 1150
Query: 989 WRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGP 1048
+ N D R R E +D R+ +D+ R S ++ R G
Sbjct: 1151 FANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSN-----RSNRSHTSGR 1205
Query: 1049 RRGGADDERSSWRNADDDRGPRRGLDD---DRGPRRGMDDDRGPRRGMDDD--RG-PRRG 1102
R ++D S+ R+ DD G +R L DR + + + G R+ D RG P R
Sbjct: 1206 LRSPSND--SAHRSGDDQSGRKRVLHSGSRDREKTKSL-EITGERKSRIDQLKRGEPSRS 1262
Query: 1103 MDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGD 1162
DR R R +D R G+ D R DRL R DR+
Sbjct: 1263 TSSDRQDSRSHSSRRSS-PESDRQVHSRSGSFDSR--------DRLQER---DRY----- 1305
Query: 1163 DSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERD-RDNQDREE-ND 1220
E ++ RE RE R + +REWDR+ ++D N+DR+ +
Sbjct: 1306 -----------------EHDRERE------RERRDTRQREWDRDADKDWPRNRDRDRLRE 1342
Query: 1221 KDPERERDRERDVDRE------DRFRRPRDEGGWRRGPAEESSSWR--DSSRRDDRDRDD 1272
++ ERERD+ RD+DRE D R RD R + + S + ++ + +RD
Sbjct: 1343 RERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDL 1402
Query: 1273 RRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADD 1315
RD +ER D +D +G ++ E S DD
Sbjct: 1403 ESTSRDSLALDKERMD-KDLGSVQGFEETNKSERTESLEAGDD 1444
Score = 57.8 bits (138), Expect = 7e-08
Identities = 69/241 (28%), Positives = 92/241 (38%), Gaps = 42/241 (17%)
Query: 1150 RRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKER 1209
R +D R GDD R V G R++EK + R+SR + + + +
Sbjct: 1207 RSPSNDSAHRSGDDQSG---RKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRST 1263
Query: 1210 DRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRD 1269
D QD R R DR R S RD + DR
Sbjct: 1264 SSDRQD--------SRSHSSRRSSPESDRQVHSRSG----------SFDSRDRLQERDRY 1305
Query: 1270 RDDRRRERDDRRDLRERRDLRD-DRDRRGPPLRSEREEVSSWRRADDRKD-DRVEERDPP 1327
DR RER +RRD R+R RD D+D R E R D R+D DR E
Sbjct: 1306 EHDRERER-ERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERE---- 1360
Query: 1328 RRVPPPALSRDRERDRDREREGEKEKASWRAE-------------KDRESLRRTKNETDE 1374
R+ ++ RDR+RDRDR E + ++ R E R+SL K D+
Sbjct: 1361 -RLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDK 1419
Query: 1375 D 1375
D
Sbjct: 1420 D 1420
Score = 51.2 bits (121), Expect = 7e-06
Identities = 60/232 (25%), Positives = 103/232 (44%), Gaps = 32/232 (13%)
Query: 717 QRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKL 776
+R +D ++ E R T+ +R+ + H +R S DR + +R ++ +
Sbjct: 1246 ERKSRIDQLKRGEPSRSTSS--DRQDSRSHSSRRSSPESDRQVH------SRSGSFDSR- 1296
Query: 777 KQFEERLAE-ERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERA 835
+RL E +R+ ER+R+R++ R+ + R+ +++ R + L+ER ERER ER
Sbjct: 1297 ----DRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRER-ERER-ERD 1350
Query: 836 KREEELREYQERVKKLEEVER-KKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRD 894
KR + RE + + E +R + R R E + E + E +L +RD
Sbjct: 1351 KRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEH---------ERD 1401
Query: 895 SEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDR 946
E T R D E +K+ +G +E R E GDDE +
Sbjct: 1402 LESTSRDSLALDKE----RMDKDLGSVQGFEETNKSERTES--LEAGDDESK 1447
Score = 49.7 bits (117), Expect = 2e-05
Identities = 69/331 (20%), Positives = 119/331 (35%), Gaps = 37/331 (11%)
Query: 726 EQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE 785
E+ E +T + K ++ K R S + +R R + + +++
Sbjct: 1166 EKVETPHVTIEDAQHRKPMDQK-RSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGR 1224
Query: 786 ERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQ 845
+R R R++ + IT R+ ++ +R E + ++ + R +
Sbjct: 1225 KRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDR 1284
Query: 846 ERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEA 905
+ + + + R +E + E +R RE ERR + W DRD++
Sbjct: 1285 QVHSRSGSFDSRDRLQERDRYEHDRERERERR------DTRQREW-DRDAD--------- 1328
Query: 906 DSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPR-RGMDD 964
K+W R RD R R+ ER +R D +RE R D V R R D
Sbjct: 1329 ----------KDWPRNRDRDRLRERERERERDKRRDLDRERE---RLISDSVERDRDRDR 1375
Query: 965 DRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDE 1024
DR + + R A + R+ + D++R D D +G +E
Sbjct: 1376 DR-TFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKER-----MDKDLGSVQGFEE 1429
Query: 1025 DRGSWRTADEDRGPRRGMDDDRGPRRGGADD 1055
S RT + G DD GA +
Sbjct: 1430 TNKSERTESLEAGDDESKLDDAHSLGSGAGE 1460
Score = 44.3 bits (103), Expect = 8e-04
Identities = 42/153 (27%), Positives = 62/153 (40%), Gaps = 22/153 (14%)
Query: 1238 RFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRG 1297
R R P ++ R G + S R+ R RE+ ++ R R D+ +RG
Sbjct: 1205 RLRSPSNDSAHRSGDDQ-------SGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRG 1257
Query: 1298 PPLR---SEREEVSSW--RRADDRKDDRVEERDPPRRVPPPALSRDR-ERDRDREREGEK 1351
P R S+R++ S RR+ D +V R RDR E DR+RERE
Sbjct: 1258 EPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRD 1317
Query: 1352 EK---------ASWRAEKDRESLRRTKNETDED 1375
+ W +DR+ LR + E + D
Sbjct: 1318 TRQREWDRDADKDWPRNRDRDRLRERERERERD 1350
Score = 41.2 bits (95), Expect = 0.007
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 19/153 (12%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
+ R EH R R E R R + +K+ R+ + + R+ E ER ++ +
Sbjct: 1301 ERDRYEHDRERER----ERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLD 1356
Query: 619 REKERILQEHEQIKKKTVRER------LEQIKKTELGAKAFKDIDIE---------DLEE 663
RE+ER++ + + + R+R +E +K+ E + + D+E D E
Sbjct: 1357 RERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKER 1416
Query: 664 LDPDFIMAKQVEQLEKEKKELQERLKNQEKKID 696
+D D + E+ K ++ + E K+D
Sbjct: 1417 MDKDLGSVQGFEETNKSERTESLEAGDDESKLD 1449
Score = 37.0 bits (84), Expect = 0.13
Identities = 56/239 (23%), Positives = 98/239 (41%), Gaps = 32/239 (13%)
Query: 559 KNSRKEHQRI--LARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEA 616
++ R+ H R R ++ER +RE+ + QRE + + R R
Sbjct: 1281 ESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRL 1340
Query: 617 KEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQ 676
+ERE+ER + + ++ RERL I D E D D + E
Sbjct: 1341 RERERERERDKRRDLDRE--RERL-----------------ISDSVERDRDRDRDRTFES 1381
Query: 677 LEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTM 736
+ E +K E K++ E + LE A +++R+ D DL Q E T
Sbjct: 1382 SQIES------VKRCEAKLE-GEHERDLESTSRDSLALDKERM-DKDLGSVQGFEE--TN 1431
Query: 737 QLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERK 795
+ ER ++LE + S+ L+D + + +++L + AE+R ++ +E K
Sbjct: 1432 KSERTESLEAGDDESK-LDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQDEEK 1489
Score = 31.2 bits (69), Expect = 7.2
Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 10/90 (11%)
Query: 1183 KAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRP 1242
++ E G RE ++ ++ D E ++ + K+ R R RE++ + + R P
Sbjct: 76 RSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTP 135
Query: 1243 RDEGGWRRGPAEESSSWRDSSRRDDRDRDD 1272
E EE+ W + RDD D D
Sbjct: 136 ESE--------EENVEW--ETNRDDSDNGD 155
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 135 bits (340), Expect = 3e-31
Identities = 114/520 (21%), Positives = 253/520 (48%), Gaps = 40/520 (7%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
QEKE + Q + + +++ +++ + + + E++E++ + ++E + RE E QK
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE-QK 391
Query: 604 VRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEE 663
+R EE Q+ + REKE ++E E++ ++ E++ + KK + K +D + E ++E
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQV--EKMREEKKMQEQEKKTRDQE-EKMQE 448
Query: 664 LDPDFIMAKQVEQLEKEKKELQERLKNQEKKI-DYFERAKRLEEIPLIKSA-YEEQRIKD 721
+ K++ + E+ +E +E+++ QE+ + + E+ + + +P K +E++++++
Sbjct: 449 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 508
Query: 722 MD--LWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQF 779
+ +WEQ+E+ R +EK + + +M R ED+ M + + E+K+
Sbjct: 509 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM-REQEDQ----MWEQEEKMRDQEQKMWDQ 563
Query: 780 EERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREE 839
EER+ E+ + +E+K +EE+ R +E E++ R EE+M++E+EE+ + + K +E
Sbjct: 564 EERM--EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 840 ELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTW 899
+ + E+ +K++E E K ++E ++ E+E + E++RL + +K+ W +
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE----QKEKLWEHEKMQEQE 677
Query: 900 RKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDD--RV 957
+ + + W + EK+ + E + D+ R+EE R +RE +R +++ R
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR------EREKKMREEEEMMRE 731
Query: 958 PRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRP 1017
M + + EE+ + + + W + +R+ ++ W H
Sbjct: 732 QEEKMQEQEEKMQEQEEEMW-----EQEEKMWEQEEKMWEQQRLPEQKEKLWEH------ 780
Query: 1018 PRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDER 1057
+ E W ++ R M RG + R
Sbjct: 781 --EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR 818
Score = 120 bits (301), Expect = 9e-27
Identities = 144/779 (18%), Positives = 338/779 (43%), Gaps = 102/779 (13%)
Query: 564 EHQRILARRQTIEERKER-LESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKE 622
E QR L+ T ++ +R +E L +R+ LE L + EE ++ A+ +EK
Sbjct: 180 ELQRALSAVSTRHKKADRYIEELTKERDALSLE-----LYRNTITNEELKKKNAELQEKL 234
Query: 623 RILQEHE---QIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAK-QVEQLE 678
+ + + Q+ K ++ +LE+ K F++ + Q L+
Sbjct: 235 PLAESEKSEIQLNVKELKRKLERAK-----------------------FLLPQVQTNTLQ 271
Query: 679 KEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL 738
+E +E L+ QEKKI E K + ++ + R ++ +W Q++ R +L
Sbjct: 272 EEMWRQEEELREQEKKIRKQEE-KMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 739 -EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQ 797
E+EK L + + E M+ + + EEK+++ EE++ + E+ K+
Sbjct: 331 REQEKELREQKELREQEEQ-----MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 385
Query: 798 RKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERK 857
R++E+++ +++EE+ +++ L+E+EER R E+ K E++ + +E KK++E E+K
Sbjct: 386 REQEQKM-----RDQEERMWEQDERLREKEERMR-EQEKMWEQVEKMREE-KKMQEQEKK 438
Query: 858 KRQRELEIEERERRREEERRL-GDSSLSRKDSRWGDRDSEGTWRKGPEADSEW--RRGPP 914
R +E +++E ER RE E+++ + R+ + E W + + EW +R P
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE---QEEKEWQQQRLPE 495
Query: 915 EKE--WRRGEGRDEDRSHRRDEERPRRLGDDED---------REPSLRPDDDRV-PRRGM 962
+KE W + + ++++ EE+ R D E+ R+ +R +D++ +
Sbjct: 496 QKEKLWEQEKMQEQEEKIWEQEEKIR---DQEEMWGQEKKMWRQEKMREQEDQMWEQEEK 552
Query: 963 DDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGL 1022
D+ + +E+R ++ + ++ +W + R R+ + ++ + R +
Sbjct: 553 MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKM 612
Query: 1023 DEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRG 1082
E + +E + ++ + + E W ++ ++ L + +
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMW--EQEEKMWEQ-EEKMWEQQRLPEQKEKLWE 669
Query: 1083 MDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRN 1142
+ + + + + + + ++ ++ + ++ W D+ R E R +
Sbjct: 670 HEKMQEQEKMQEQE---EKIWEQEKMEKKTQEQEKKTW-----DQEKMREEESMREREKK 721
Query: 1143 MDDDRLSRRADDDRFPRRGD---DSRPGPWRPLVKPGGWREKEKAREESWGPPR------ 1193
M ++ R +++ + + + W K W ++EK E+ P +
Sbjct: 722 MREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM--WEQEEKMWEQQRLPEQKEKLWE 779
Query: 1194 -ESRPSEEREWDR-EKERDRDNQDREENDK---DPERERDRERDVDREDRFRRPRDEGGW 1248
E +E+ W++ EK RD++ + R + +K E+ R +E + ++ ++E W
Sbjct: 780 HEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMW 839
Query: 1249 RRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEV 1307
+E W + +++ + + R+ +R + + +++ + +R + E++
Sbjct: 840 ----GQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK---MRGQEEKI 891
Score = 119 bits (299), Expect = 2e-26
Identities = 118/488 (24%), Positives = 243/488 (49%), Gaps = 43/488 (8%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIE 576
+++R Q M K E + +EK + + + K R++ Q++ + + +
Sbjct: 341 KELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMW 400
Query: 577 ERKERLESLNIQREKEE-LEQREAELQKVRKAEEERL--RQEAKEREKERILQEHEQIKK 633
E+ ERL REKEE + ++E ++V K EE+ QE K R++E +QE E+I++
Sbjct: 401 EQDERL------REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454
Query: 634 --KTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQL-EKEK-KELQERLK 689
K +RE E +++ E + ++ E E+ + +Q E+L E+EK +E +E++
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514
Query: 690 NQEKKI-----------DYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEE-ERITTMQ 737
QE+KI + + K E+ + E+ R ++ +W+Q+E E+ T Q
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574
Query: 738 LEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQ 797
++ E K R + +R+ MR + EEK+++ EE++ E+ E+ ++
Sbjct: 575 EKKTWDQEEKMREEERMREREK-KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 798 RKEERRITYYREKE-EEEQRRAEEQMLKEREER-ERAERAKREEELREYQERVKKLEEVE 855
+++E ++ EK E+E++ E+Q L E++E+ E+ + +E+++E +E++ + E++E
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 856 RKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPE 915
+K +++E + ++E+ REEE R++ R+ E ++ E E E
Sbjct: 694 KKTQEQEKKTWDQEKMREEESMREREKKMREEEEM-MREQEEKMQEQEEKMQEQEEEMWE 752
Query: 916 KEWRRGEGRDEDRSHRRDEERPRRLGDDE---------DREPSLRPDDDRVPRRGMDDDR 966
+E + E ++ +R E+ +L + E ++E +R ++++ RG ++
Sbjct: 753 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKM--RGQEE-- 808
Query: 967 GPRRGPEE 974
RG EE
Sbjct: 809 -KMRGQEE 815
Score = 119 bits (297), Expect = 3e-26
Identities = 135/723 (18%), Positives = 303/723 (41%), Gaps = 93/723 (12%)
Query: 675 EQLEKEKKELQERL-----KNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQE 729
E+L+K+ ELQE+L + E +++ E ++LE + + +++ ++W Q+E
Sbjct: 221 EELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE-EMWRQEE 279
Query: 730 EERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN 789
E R E+EK + + E+R +R + + EEK+ + E+RL E+
Sbjct: 280 ELR------EQEKKIRKQEEKMWRQEER----LREQEGKMREQEEKMWRQEKRLREQE-- 327
Query: 790 RLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVK 849
+E + Q KE R RE+EE+ Q + E+ +E + RE+ E+ R+EE QE K
Sbjct: 328 --KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE--K 383
Query: 850 KLEEVERKKRQRELEI-EERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSE 908
++ E E+K R +E + E+ ER RE+E R+ R+ E W + + E
Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERM--------------REQEKMWEQVEKMREE 429
Query: 909 WRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDD--EDREPSLRPDDDRVPRRGMDDDR 966
+ EK+ R E + ++ R+ E+ R ++ ++E ++ ++ + + + +
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Query: 967 GPRRGPEEDRF--SRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDE 1024
R ++++ + + + W + R + +++ WR + ++
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-------EKMREQ 542
Query: 1025 DRGSWRTADEDRGPRRGM-DDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGM 1083
+ W ++ R + M D + + + E+ +W + R R + ++ R
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602
Query: 1084 DDDRGPRRGMDDDRGPRRGMDD---------DRGPRRGLDDDRGPWRNADDDRIPRRGAE 1134
+ R M + + ++ + + + W + +R E
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662
Query: 1135 DDRGPWRN---MDDDRLSRRAD----DDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREE 1187
W + + +++ + + ++ ++ + W ++EK REE
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW----------DQEKMREE 712
Query: 1188 SWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRF----RRP- 1242
RE + EE E RE+E Q+ + +++ E E+ ++E++ R P
Sbjct: 713 ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772
Query: 1243 RDEGGWRRGPAEESSS-WRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLR 1301
+ E W +E W + RD++++ R ++++ +E + + G +
Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKM--RDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 1302 SEREEVSSWRRADDR--KDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAE 1359
+E W + + +++++EE+ + ++ R+++ + G++EK + E
Sbjct: 831 MWGQEEKMWGQEEKMWGQEEKMEEKMQGQ--------EEKMREQEEKMRGQEEKMREQEE 882
Query: 1360 KDR 1362
K R
Sbjct: 883 KMR 885
Score = 103 bits (256), Expect = 1e-21
Identities = 87/387 (22%), Positives = 194/387 (50%), Gaps = 36/387 (9%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREK 621
R+E R + +E K R + + ++E +E++ E +K +EE++R+E + RE+
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594
Query: 622 ERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEK 681
E+ ++E E++ ++ + EQ +K + + + + E ++E + M +Q E++ +++
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE-EKMQEQEEK--MWEQEEKMWEQE 651
Query: 682 KELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLERE 741
+++ E+ + E+K +E K E+ E+ + ++ +WEQ++ E+ T E+E
Sbjct: 652 EKMWEQQRLPEQKEKLWEHEKMQEQ--------EKMQEQEEKIWEQEKMEKKTQ---EQE 700
Query: 742 KALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEE 801
K + +M R+ MR + + EE +++ EE++ E+ E+ + ++E
Sbjct: 701 KKTWDQEKM------REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Query: 802 RRITYYREKEEEEQRRAEE-QMLKEREERERAERA-KREEELREYQERVKKLEEVERKKR 859
++ EK E+QR E+ + L E E+ + E+ ++EE++R+ +E+++ EE
Sbjct: 755 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE------ 808
Query: 860 QRELEIEERERRREEERRLG--DSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKE 917
++ +E + R +EE+ G + +++ WG E W G E E + E++
Sbjct: 809 --KMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWG--QEEKMW--GQEEKMEEKMQGQEEK 862
Query: 918 WRRGEGRDEDRSHRRDEERPRRLGDDE 944
R E + + + E+ + G +E
Sbjct: 863 MREQEEKMRGQEEKMREQEEKMRGQEE 889
Score = 99.4 bits (246), Expect = 2e-20
Identities = 83/339 (24%), Positives = 170/339 (50%), Gaps = 24/339 (7%)
Query: 545 EKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKV 604
EK+ Q Q T + +E +R+ R + + E +E + RE+EE Q + E K+
Sbjct: 568 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM------REQEEKMQEQEE--KM 619
Query: 605 RKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEEL 664
++ EE+ QE K +E+E + E E+ + + EQ + E K ++ +++ E++
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 665 DPDFIMAKQVEQLEKEKKELQERLKNQEKKID---YFERAKRLEEIPLIKSAYEEQRIKD 721
+ E++EK+ +E +++ +QEK + ER K++ E + EE+ +
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQ 739
Query: 722 MDLWEQQEEERITTMQLEREKALEHKNRM---SRMLEDRDLFVMRLKAARQSVYEEKLKQ 778
+ ++QEEE M + EK E + +M R+ E ++ K Q EK+ +
Sbjct: 740 EEKMQEQEEE----MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ----EKIWE 791
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREK--EEEEQRRAEEQMLKEREERERAERAK 836
EE++ ++ + ++ R +E ++ EK +EE+ +E+ + +EE+ + K
Sbjct: 792 QEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEK 851
Query: 837 REEELREYQERVKKLEEVERKKRQRELEIEERERRREEE 875
EE+++ +E++++ EE R + ++ E EE+ R +EE+
Sbjct: 852 MEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 97.1 bits (240), Expect = 1e-19
Identities = 83/369 (22%), Positives = 183/369 (49%), Gaps = 30/369 (8%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
QEK+ Q + ++ +++ + Q + +++ER+E ++EK+ +Q E ++
Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE 588
Query: 604 VRKAEEERLRQEAKE--REKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDL 661
R E E+ +E +E RE+E +QE E+ ++ + EQ +K + + + + +
Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648
Query: 662 EELDPDFIMAKQVEQLEK----EKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQ 717
E+ + + + EQ EK EK + QE+++ QE+KI E+ ++ K+ +E+
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEK-------KTQEQEK 701
Query: 718 RIKDMDLWEQQEE--ERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEK 775
+ D + ++E ER M+ E E E + +M E + + ++E++
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE 761
Query: 776 LKQFEE-RLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834
K +E+ RL E++ E K Q +E+ + +++EE+ R +E+ ++ +EE+ R +
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 835 AK----------REEELREYQERV----KKLEEVERKKRQRELEIEERERRREEERRLGD 880
K +EE++ +E++ +K+EE + + ++ E EE+ R +EE+ R +
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881
Query: 881 SSLSRKDSR 889
+ ++ +
Sbjct: 882 EKMRGQEEK 890
Score = 86.7 bits (213), Expect = 1e-16
Identities = 142/801 (17%), Positives = 319/801 (39%), Gaps = 114/801 (14%)
Query: 592 EELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEL--- 648
E+ +Q A+L++ +KA + QEA RE E Q+H T+R + +KTEL
Sbjct: 70 EDTQQNRAQLKEEKKASHQH--QEALRREIEA--QDH------TIR--ILTCQKTELETA 117
Query: 649 ------GAKAFKDIDIEDLEELDPDFIMAKQVEQL--------EKEKKELQERLKNQEKK 694
A+ F+D ++ + A + L E K+L RL +
Sbjct: 118 LYYSQDAARKFEDGNLGTPSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHF 177
Query: 695 IDYFERAKRLEEIPLIKS-AYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRM 753
+RA K+ Y E+ K+ D + T + ++K E + ++
Sbjct: 178 AGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLPLA 237
Query: 754 LEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEE 813
++ + +K ++ KL++ + L + + N L+E +++EE R E+E
Sbjct: 238 ESEKSEIQLNVKELKR-----KLERAKFLLPQVQTNTLQEEMWRQEEELR-------EQE 285
Query: 814 EQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRRE 873
++ R +E+ + +EER R + K E+ + + K+L E E++ R++E E+ E++ RE
Sbjct: 286 KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345
Query: 874 EERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRD 933
+E ++ + E W + E R EK WR+ E E R+
Sbjct: 346 QEEQMQEQE-------------EKMWEQ-----EEKMREQEEKMWRQEERLWEQEKQMRE 387
Query: 934 EERPRRLGDDEDREPSLRPDDDRVPRRG--MDDDRGPRRGPEEDRFSRRGADDDRPSWRN 991
+E+ R D+E + D+R+ + M + E+ R ++ + ++ +
Sbjct: 388 QEQKMR-----DQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 992 TDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGP--- 1048
+ + RI + ++ + R + + + +E ++ + + +
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 1049 RRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRG 1108
+ + E W + R D+ G + + M + ++
Sbjct: 503 QEKMQEQEEKIWEQEEKIR--------DQEEMWGQEKKMWRQEKMREQEDQMWEQEE--- 551
Query: 1109 PRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGP 1168
+ D ++ W ++R+ ++ E ++ W D+ + +++R R R
Sbjct: 552 --KMRDQEQKMWDQ--EERMEKKTQEQEKKTW-----DQEEKMREEERMREREKKMRE-- 600
Query: 1169 WRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERD 1228
+ RE+E+ +E + + EE+ W++E++ Q++EE + E +
Sbjct: 601 -----EEEMMREQEEKMQEQ---EEKMQEQEEKMWEQEEKM----QEQEEKMWEQEEKMW 648
Query: 1229 RERDVDREDRFRRPRDEGGWRRGPAEESSSWRD------SSRRDDRDRDDRRRERDDRRD 1282
+ + E + + E W +E ++ + ++ ++ ++ D+
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708
Query: 1283 LRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERD 1342
+RE +R+ R +R E E + ++++++E++ + E+
Sbjct: 709 MREEESMRE----REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Query: 1343 RDREREGEKEKASWRAEKDRE 1363
+++R E+++ W EK +E
Sbjct: 765 WEQQRLPEQKEKLWEHEKMQE 785
Score = 81.3 bits (199), Expect = 6e-15
Identities = 73/308 (23%), Positives = 164/308 (53%), Gaps = 40/308 (12%)
Query: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERL---ESLNIQREKEELEQREA 599
+QE+EE+ Q ++ +++ + + ++E++E++ E ++E++ EQ+
Sbjct: 612 MQEQEEKMQ-----------EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660
Query: 600 ELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIE 659
QK + E E+++++ K +E+E + E E+++KKT EQ KKT K ++ +
Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ----EQEKKTWDQEKMREEESMR 716
Query: 660 DLEELDPDFIMAKQVEQLEKEKKELQERL-KNQEKKIDYFERAKRLEEIPLIKSAYEEQR 718
+ E+ M ++ E + ++++++QE+ K QE++ + +E+ +++ E + +E+QR
Sbjct: 717 EREKK-----MREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE--EKMWEQQR 769
Query: 719 IKDMD--LWEQ---QEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYE 773
+ + LWE QE+E+I E+E+ + + R E++ MR + + E
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIW----EQEEKMRDQEEKMRGQEEK----MRGQEEKMRGQE 821
Query: 774 EKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREE-RERA 832
EK+ EE++ + + ++ +E ++ + +EE+ R EE+M + E+ RE+
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881
Query: 833 ERAKREEE 840
E+ + +EE
Sbjct: 882 EKMRGQEE 889
Score = 61.6 bits (148), Expect = 5e-09
Identities = 47/266 (17%), Positives = 109/266 (40%), Gaps = 29/266 (10%)
Query: 1141 RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEE 1200
+ M + R ++R + + R R + W + EK REE +E + ++
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQ 442
Query: 1201 REWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWR 1260
E +E+ER R+ + + +++ RE++ + E+ + + E +R P ++ W
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 1261 DSSRRDDRD-----------------------RDDRRRERDDR-----RDLRERRDLRDD 1292
++ + R ++ RE++D+ +R++ D
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 562
Query: 1293 RDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRERE-GEK 1351
++ R E+E+ + + R+++R+ ER+ R + E+ +++E + E+
Sbjct: 563 QEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 622
Query: 1352 EKASWRAEKDRESLRRTKNETDEDGW 1377
E+ W E+ + E +E W
Sbjct: 623 EEKMWEQEEKMQEQEEKMWEQEEKMW 648
Score = 61.2 bits (147), Expect = 6e-09
Identities = 47/226 (20%), Positives = 109/226 (48%), Gaps = 30/226 (13%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKE-RDRDNQDREENDK--------------- 1221
WR++E+ RE+ ++ R EE+ W +E+ R+++ + RE+ +K
Sbjct: 275 WRQEEELREQE----KKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKEL 330
Query: 1222 -DPERERDRERDVDREDRFRRPRDEGGWRRGP---AEESSSWRDSSRRDDRDRDDRRRER 1277
+ E+E ++++ ++ + ++E W + +E WR R ++++ R +E+
Sbjct: 331 REQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQ 390
Query: 1278 DDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSR 1337
RD ER +D+R R E+E++ W + + ++++ + + +
Sbjct: 391 -KMRDQEERMWEQDERLREKEERMREQEKM--WEQVEKMREEKKMQEQEKKTRDQEEKMQ 447
Query: 1338 DRERDRDREREGEKEKASWRAEKDRESLRRTKN--ETDEDGWTTVR 1381
+ ER R+RE++ +E+ + R E++ + ++ +N E +E W R
Sbjct: 448 EEERIREREKKMREEEETMR-EQEEKMQKQEENMWEQEEKEWQQQR 492
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 125 bits (314), Expect = 3e-28
Identities = 111/439 (25%), Positives = 227/439 (51%), Gaps = 55/439 (12%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERL---ESLNIQREKEELEQREAE 600
QEK+ + Q + R + +R+ + + + E++ER+ E + Q EK + E+R E
Sbjct: 343 QEKQMREQE------QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Query: 601 LQKVRKAEEERLRQEAKEREK------ERILQEHEQIKKKTVRERL-EQIKKTELGAKAF 653
+K + EEE +R++ ++ +K E+ +E +Q + +E+L EQ K E K +
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 654 KDID-IEDLEEL---DPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPL 709
+ + I D EE+ + +++ + E + E +E++++QE+K+ +++ +R+ E
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM--WDQEERMWEQDE 514
Query: 710 IKSAYEEQRIKDMDLWEQQEEERITTMQLEREKAL---EHKNRMSRMLEDRDLFV----- 761
EE+ + +W+Q+E+ R E+EK E K R + +R+ +
Sbjct: 515 RLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
Query: 762 -MRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEE 820
MR + + EEK+++ EE++ E+ E+ ++ ++E ++ E+EEE++ + +E
Sbjct: 575 MMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW---EQEEEDKMQEQE 631
Query: 821 QMLKEREERERAERAK---REEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877
+M+ E+EE+ + + K +EE++RE +E++++ EE + + ++ E EE+ + +EE+ R
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMR 691
Query: 878 LGDSSL-SRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRD-EDRSHRRDEE 935
+ + +++ WG E W G EK W + E R+ E+R + E+
Sbjct: 692 EQEEKMRGQEEKMWG--QEEKMW------------GQEEKMWGQEEMREKEERIRDQKEK 737
Query: 936 RPRRLGDDEDR--EPSLRP 952
RL + E+R EP L P
Sbjct: 738 MQERLPEHEERCSEPCLPP 756
Score = 121 bits (303), Expect = 5e-27
Identities = 95/407 (23%), Positives = 218/407 (53%), Gaps = 39/407 (9%)
Query: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQ 602
L+ K E+ + + N+ +E +E+K R + + R++E L ++E
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEG--- 269
Query: 603 KVRKAEEERLRQEAKEREKERILQEHEQI--KKKTVRERLEQIKKTELGAKAFKDIDIED 660
K+R+ EE+ RQE + RE+E+ L+E E+ ++K +RE+ EQ+++ E + + + +
Sbjct: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQE---EKMWEQEEKM 326
Query: 661 LEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
E+ + + +++ + EK+ +E ++++++QE+++ +E+ +RL E +E+R++
Sbjct: 327 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM--WEQDERLRE--------KEERMR 376
Query: 721 DMD-LWEQ----QEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEK 775
+ + +WEQ QEEERI EREK + + R E++ ++ ++++E++
Sbjct: 377 EQEKMWEQEEKMQEEERIR----EREKKMREEEETMREQEEK------MQKQEENMWEQE 426
Query: 776 LKQFEERLAEERHNRLEERKRQRKEERRITYYREK--EEEEQRRAEEQMLKEREERERAE 833
K+++++ E+ +L E+++ +++E +I EK ++EE E++M ++ + RE+ +
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 834 RAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDR 893
+ +EE QE+ K+ + E + +++ + E+E R E++++ ++ +
Sbjct: 487 QMWEQEEKMRDQEQ--KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQE 544
Query: 894 DSEGTWRKGPEADSEWRRGPPEKEWRRGEG--RDEDRSHRRDEERPR 938
+ TW + + E R EK+ R E R+++ + EE+ R
Sbjct: 545 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Score = 115 bits (288), Expect = 3e-25
Identities = 104/473 (21%), Positives = 234/473 (49%), Gaps = 47/473 (9%)
Query: 562 RKEHQRILARRQTI-EERKERLESLNIQREKEELEQREAEL----QKVRKAEEERLRQEA 616
R++ +R+ + + + E+ KE E ++ ++E+++++E ++ +K+R+ EE+ RQE
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 617 KEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQ 676
+ E+E+ ++E EQ K + ER+ + + L K + + E + E + +++ +
Sbjct: 339 RLWEQEKQMREQEQ-KMRDQEERMWE-QDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Query: 677 LEKEKKELQERLKNQEKKI--------DYFERAKRLEEIPLIKSA-YEEQRIKDMD--LW 725
EK+ +E +E ++ QE+K+ + E+ + + +P K +E++++++ + +W
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 726 EQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVY--EEKLKQFEERL 783
EQ+E+ R +EK + + +M + +++ Q ++ EE++ + +ERL
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516
Query: 784 AEERHNRLEERKRQRKEER----RITYYREK---EEEEQRRAEEQMLKEREERERAERAK 836
E+ E++K ++EE+ + T +EK ++EE+ R EE+M RER ++ +
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM------REREKKMR 570
Query: 837 REEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSE 896
EEE+ QE +K++E E K R++E ++ E+E + +E+ + + ++ + +++ E
Sbjct: 571 EEEEMMREQE--EKMQEQEEKMREQEEKMWEQEEKMQEQ----EEKMWEQEEKMWEQEEE 624
Query: 897 GTWRKGPE---ADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPD 953
++ E E + EK W + E E R++E + +++ RE +
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 954 DDRVPRRGMDDDRGPRRGPEEDRFSRRGA--DDDRPSWRNTDDDRPPRRIADE 1004
R ++ RG EE + + + W + RI D+
Sbjct: 685 GQEEKMREQEE---KMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734
Score = 114 bits (286), Expect = 5e-25
Identities = 143/683 (20%), Positives = 293/683 (42%), Gaps = 94/683 (13%)
Query: 564 EHQRILARRQTIEERKER-LESLNIQREKEELEQ-----REAELQKVRKAEEERLRQEAK 617
E QR L+ T ++ +R +E L +R+ LE EL+K +E+LR
Sbjct: 142 ELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLR--LA 199
Query: 618 EREKERILQEHEQIKKKTVRER--LEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVE 675
E EK I +++K+K R + L Q++ L + ++ E+L E + K++
Sbjct: 200 ESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE--EELREQE------KKIR 251
Query: 676 QLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQE-EERIT 734
+ E++ +ERL+ QE K+ E R +E L + +E R ++ +L EQ++ E+
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRL-REQEKELREQEKELREQKKLREQEE 310
Query: 735 TMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEER 794
MQ + EK E + +M EEK+ + EERL E+ E+
Sbjct: 311 QMQEQEEKMWEQEEKMREQ-------------------EEKMWRQEERLWEQEKQMREQE 351
Query: 795 KRQRKEERRITYYRE--KEEEEQRRAEEQMLKEREERERAERAK-REEELREYQERVKKL 851
++ R +E R+ E +E+EE+ R +E+M ++ E+ + ER + RE+++RE +E +++
Sbjct: 352 QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQ 411
Query: 852 EEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPE-ADSEWR 910
EE K +++E + E+E + +++RL + + E W + + D E
Sbjct: 412 EE---KMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM 468
Query: 911 RGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRR 970
G +K WR+ + R+++ EE+ R D+E + ++R+ + D R
Sbjct: 469 WGQEKKMWRQEKMREQEDQMWEQEEKMR------DQEQKMWDQEERM----WEQDERLRE 518
Query: 971 GPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWR 1030
E R + + W+ + R ++ ++++ W + R R + ++
Sbjct: 519 KEERMR-------EQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 571
Query: 1031 TADEDRGPRRGMDDDRGPRRGGADDERSSWRNAD--DDRGPRRGLDDDRGPRRGMDDDRG 1088
+ R M + R + E W + ++ + +++ + +D
Sbjct: 572 EEEMMREQEEKMQEQEEKMR---EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ 628
Query: 1089 PRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRL 1148
+ M ++ + +++ + + R ++ R E +G M +
Sbjct: 629 EQEEMMWEQEEKMQEQEEK-----MWEQEEKMREQEEKM--REQEEKMQGQEEKMREQEE 681
Query: 1149 SRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREES-WGPPRESRPSEEREWDREK 1207
+ +++ + + R G EK +EE WG EE+ W +E+
Sbjct: 682 KMQGQEEKMREQEEKMR-----------GQEEKMWGQEEKMWG-------QEEKMWGQEE 723
Query: 1208 ERDRDNQDREENDKDPERERDRE 1230
R+++ + R++ +K ER + E
Sbjct: 724 MREKEERIRDQKEKMQERLPEHE 746
Score = 114 bits (285), Expect = 6e-25
Identities = 155/769 (20%), Positives = 323/769 (42%), Gaps = 131/769 (17%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKER-- 619
+ HQ A R+ IE + + L Q K ELE Q + E+ E+K+
Sbjct: 74 KASHQHQEALRREIEAQDHTIRILTCQ--KTELETALYYSQDAARKFEDGNLGESKDLAG 131
Query: 620 ----------EKERILQEHEQIKKKTVRERLEQIKKTE-LGAKAFKD-IDIEDLEELDPD 667
E +R L KK R E K+ + L + +++ I E+L++ + +
Sbjct: 132 RLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAE 191
Query: 668 FIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQ 727
+ +++ E EK E+Q +K ++K+ ERAK L +P +++ ++ ++W Q
Sbjct: 192 --LQEKLRLAESEKSEIQLNVKELKRKL---ERAKFL--LPQVQTNTLQE-----EMWRQ 239
Query: 728 QEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE-- 785
+EE R E+EK + + E+R +R + + EEK+++ E+RL E
Sbjct: 240 EEELR------EQEKKIRKQEEKMWRQEER----LREQEGKMREQEEKMRRQEKRLREQE 289
Query: 786 ----ERHNRLEERKRQRKEERRITYYREK---EEEEQRRAEEQMLKEREERERAERAKRE 838
E+ L E+K+ R++E ++ EK +EE+ R EE+M ++ E E+ RE
Sbjct: 290 KELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 839 EE--LREYQERVKKLEEVERKKRQRELEIE---ERERRREEERRLGDSSLSRKDSRWGDR 893
+E +R+ +ER+ + +E R+K +R E E E+E + +EE R+ + ++ R
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMR 409
Query: 894 DSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDE---DREPSL 950
+ E +K + ++ W + EKEW++ +R E+ +L + E ++E +
Sbjct: 410 EQEEKMQK--QEENMWEQ--EEKEWQQ----------QRLPEQKEKLWEQEKMQEQEEKI 455
Query: 951 RPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPP-RRIADEDRGNW 1009
++++ R ++ G + R D W + R +++ D++ W
Sbjct: 456 WEQEEKI--RDQEEMWGQEKKMWRQEKMREQEDQ---MWEQEEKMRDQEQKMWDQEERMW 510
Query: 1010 RHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGP 1069
+ R + E + W+ ++ R ++ + E+ +W + R
Sbjct: 511 EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ-----------EKKTWDQEEKMREE 559
Query: 1070 RRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIP 1129
R + ++ R + R M + R ++ W +
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM------------WEQEE----- 602
Query: 1130 RRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREES- 1188
+ E + W ++++ + ++D+ + + W ++EK +E+
Sbjct: 603 -KMQEQEEKMWEQ--EEKMWEQEEEDKMQEQEEMM-------------WEQEEKMQEQEE 646
Query: 1189 --WGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEG 1246
W + R EE+ RE+E Q+ + +++ + + E+ ++E++ R ++E
Sbjct: 647 KMWEQEEKMREQEEKM--REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM-RGQEEK 703
Query: 1247 GWRRGPAEESSSWRDSSRR--DDRDRDDRRRERDDRRDLRERRDLRDDR 1293
W +E W + + R+ R RD + ++ER ++R
Sbjct: 704 MW----GQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
Score = 87.8 bits (216), Expect = 6e-17
Identities = 90/368 (24%), Positives = 180/368 (48%), Gaps = 69/368 (18%)
Query: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERL-ESLNIQREKEELEQREAEL 601
++E+EE+ Q + KE Q+ Q + E+KE+L E +Q ++E++ ++E ++
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQ-----QRLPEQKEKLWEQEKMQEQEEKIWEQEEKI 462
Query: 602 ----------------QKVRKAEEERLRQEAKEREKE--------RILQEHEQIKKKTVR 637
+K+R+ E++ QE K R++E R+ ++ E++++K R
Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 638 ERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDY 697
R EQ K + K ++ ++ E+ D ++EK +ER++ +EKK+
Sbjct: 523 MR-EQKKMWQQEEKMREEKKTQEQEKKTWD----------QEEKMREEERMREREKKMRE 571
Query: 698 FERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRM------S 751
E R +E + + E+ R ++ +WEQ+E+ MQ + EK E + +M
Sbjct: 572 EEEMMREQEEKM-QEQEEKMREQEEKMWEQEEK-----MQEQEEKMWEQEEKMWEQEEED 625
Query: 752 RMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREK- 810
+M E ++ M + + EEK+ + EE++ E+ E+ ++ + +E ++ EK
Sbjct: 626 KMQEQEEM--MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Query: 811 ---EEEEQR-----RAEEQMLKEREERERAERAKR--EEELREYQERVKKLEEVERKKRQ 860
EE+ + R +E+ + +EE+ + K +EE+RE +ER++ +E K ++
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE---KMQE 740
Query: 861 RELEIEER 868
R E EER
Sbjct: 741 RLPEHEER 748
Score = 75.1 bits (183), Expect = 4e-13
Identities = 120/680 (17%), Positives = 273/680 (40%), Gaps = 83/680 (12%)
Query: 711 KSAYEEQRIKDMDLWEQQEEERITTMQ-LEREKALEHKNRMSRMLEDRDLFVMRLKAARQ 769
K++++ Q ++ Q RI T Q E E AL + +R ED +L + A R
Sbjct: 74 KASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGESKDLAGRL 133
Query: 770 SVYEEKLKQFEERLA-----EERHNRLEERKRQRKEERRITYYRE---KEEEEQRRAEEQ 821
+ + L+ ++ +R E + ++ + YR EE +++ AE Q
Sbjct: 134 HHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQ 193
Query: 822 MLKEREERERAERAKREEELREYQERVK-KLEEVERKKRQRELEIEERERRREEER-RLG 879
E E++E +EL+ ER K L +V+ Q E+ +E E R +E++ R
Sbjct: 194 EKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ 253
Query: 880 DSSLSRKDSRWGDRDSEGTWRKGPEA--DSEWRRGPPEKEWRRGEGRDEDRSHRRDEERP 937
+ + R++ R R+ EG R+ E E R EKE R E ++ R++E
Sbjct: 254 EEKMWRQEERL--REQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 938 RRLGDDE--DREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDD 995
+ +++ ++E +R ++++ R+ ++R + + ++ D + W +
Sbjct: 312 MQEQEEKMWEQEEKMREQEEKMWRQ---EERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 996 RPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADD 1055
R E W + + R + ++ + +E+ R + + +
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREK---KMREEEETMREQEEKMQKQEENMWEQ 425
Query: 1056 ERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDD 1115
E W+ ++ L + + + + + + R ++ G + +
Sbjct: 426 EEKEWQ--------QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM-- 475
Query: 1116 DRGPWRNADDDRIPRRGAEDDRGPWRN---MDDDRLSRRADDDRFPRRGDDSRPGPWRPL 1172
WR + E + W M D ++R + + R R
Sbjct: 476 ----WRQ-------EKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR 524
Query: 1173 VKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERD 1232
+ W+++EK REE ++++ E++ WD+E +K E ER RER+
Sbjct: 525 EQKKMWQQEEKMREE-----KKTQEQEKKTWDQE-------------EKMREEERMRERE 566
Query: 1233 --VDREDRFRRPRDEGGWRRGP---AEESSSWRDSSRRDDR-----DRDDRRRERDDRRD 1282
+ E+ R ++E + +E W + ++ +++++ E+++
Sbjct: 567 KKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK 626
Query: 1283 LRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERD 1342
++E+ ++ +++ + + +E W + + ++ + R+ ++ ++ R+
Sbjct: 627 MQEQEEMMWEQEE-----KMQEQEEKMWEQEEKMREQEEKMREQEEKMQG---QEEKMRE 678
Query: 1343 RDREREGEKEKASWRAEKDR 1362
++ + +G++EK + EK R
Sbjct: 679 QEEKMQGQEEKMREQEEKMR 698
Score = 64.7 bits (156), Expect = 6e-10
Identities = 43/207 (20%), Positives = 104/207 (50%), Gaps = 17/207 (8%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKERDRDNQ--DREENDKDPERERDRERDVDR 1235
W ++EK ++ P ++ E+ W++EK ++++ + ++EE +D E +E+ + R
Sbjct: 423 WEQEEKEWQQQRLPEQK-----EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 1236 EDRFRRPRDEGGWRRGPA---EESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDD 1292
+++ R D+ W + +E W R ++D+R RE+++R +RE++ +
Sbjct: 478 QEKMREQEDQM-WEQEEKMRDQEQKMWDQEERM--WEQDERLREKEER--MREQKKMWQQ 532
Query: 1293 RDRRGPPLRSEREEVSSWRRADD-RKDDRVEERDPPRRVPPPALSRDRERDRDRERE-GE 1350
++ +++ +E +W + + R+++R+ ER+ R + E+ +++E + E
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 1351 KEKASWRAEKDRESLRRTKNETDEDGW 1377
+E+ W E+ + E +E W
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Score = 60.8 bits (146), Expect = 8e-09
Identities = 54/261 (20%), Positives = 116/261 (44%), Gaps = 31/261 (11%)
Query: 1141 RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEE 1200
+ M + R ++R + + R R + W ++EK +EE RE + EE
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREE 404
Query: 1201 REWDREKERDRDNQDR---EENDKDPERER---------DRERDVDREDRF----RRPRD 1244
E RE+E Q+ E+ +K+ +++R ++E+ ++E++ + RD
Sbjct: 405 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 464
Query: 1245 -EGGWRRGPAEESSSWRDSSRRDDRDR--DDRRRERDDRRDLRERRDLRDDRDRRGPPLR 1301
E W +E WR R+ D+ + + RD + + ++ + ++D R LR
Sbjct: 465 QEEMW----GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER---LR 517
Query: 1302 SE----REEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
+ RE+ W++ + ++++ + + R+ ER R+RE++ +E+ R
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 1358 AEKDRESLRRTK-NETDEDGW 1377
++++ + K E +E W
Sbjct: 578 EQEEKMQEQEEKMREQEEKMW 598
Score = 55.5 bits (132), Expect = 4e-07
Identities = 42/208 (20%), Positives = 101/208 (48%), Gaps = 14/208 (6%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKE-RDRDNQDREENDKDPERE-RDRERDVDR 1235
WR++E+ RE+ ++ R EE+ W +E+ R+++ + RE+ +K +E R RE++ +
Sbjct: 237 WRQEEELREQE----KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
Query: 1236 EDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDR 1295
++ + R++ R E +++++ RE++++ +E R ++
Sbjct: 293 REQEKELREQKKLR-----EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 347
Query: 1296 RGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKAS 1355
R + +E W + + ++ R+ + ++ ER R+RE++ +E+ +
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 1356 WRAEKDRESLRRTKN--ETDEDGWTTVR 1381
R E++ + ++ +N E +E W R
Sbjct: 408 MR-EQEEKMQKQEENMWEQEEKEWQQQR 434
Score = 55.1 bits (131), Expect = 5e-07
Identities = 44/220 (20%), Positives = 96/220 (43%), Gaps = 30/220 (13%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWD-----REKERDRDNQDR----EENDKDPERERD 1228
W ++++ RE+ ++ R EER W+ REKE Q++ EE ++ ER R+
Sbjct: 341 WEQEKQMREQE----QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIRE 396
Query: 1229 RERDVDREDRFRRPRDEGGWRRGP---AEESSSWRDSSRRDDRDR--DDRRRERDDRRDL 1283
RE+ + E+ R ++E ++ +E W+ + +++ + + + + +
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 1284 RERRDLRDDRDRRGPPLRSEREEV------SSWRRADDRKDDRVEERDPPRRVPPPALSR 1337
+ +RD + G + R+E W + + +D + D R +
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER-----MWE 511
Query: 1338 DRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGW 1377
ER R++E ++K W+ E+ ++T+ E ++ W
Sbjct: 512 QDERLREKEERMREQKKMWQQEEKMREEKKTQ-EQEKKTW 550
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 119 bits (299), Expect = 2e-26
Identities = 101/422 (23%), Positives = 221/422 (52%), Gaps = 56/422 (13%)
Query: 520 RNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERK 579
+ QL A + L K L+ + LQ + E+++L + + ++++ +++ + + I+E +
Sbjct: 260 QQQLQAEADHLGKELQSVSAK--LQAQVEENEL----WNRLNQQQEEKMWRQEEKIQEWE 313
Query: 580 ERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQI--KKKTVR 637
E+ IQ ++E++ ++E +K+R+ EE+ RQE EKE ++ E++ +K+
Sbjct: 314 EK-----IQEQEEKIREQE---EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 638 ERLEQI------KKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEK---------- 681
RLE++ K EL K + I + EE + ++ E+ ++++
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 682 KELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLERE 741
+E +E+++ QEKK+ + + +++ E I+ EE+R + ++W Q+E+ R ++ R+
Sbjct: 426 REQEEKIREQEKKM--WRQEEKIHEQEKIRE--EEKRQEQEEMWRQEEKIR-EQEEIWRQ 480
Query: 742 KALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEE 801
K H+ R E+ K RQ EEK+ EE++ E+ + ++ R++E
Sbjct: 481 KEKMHEQEKIRKQEE--------KVWRQ---EEKMHDQEEKIREQEEKMWRQEEKIREQE 529
Query: 802 RRITYYREKEEEEQRRAEEQMLKEREER--ERAERAKREEELREYQERVKKLEEVERKKR 859
+I +E+EE+ R +E+M++E+EE+ E+ E+ + +E++R +E++++ EE R+++
Sbjct: 530 EKI-----REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSR-WGDRDSEGTWRKGPEADSEWRRGPPEKEW 918
++ E EE+ +EE+ R + + ++ + W + + + E R EK W
Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 644
Query: 919 RR 920
+
Sbjct: 645 EQ 646
Score = 111 bits (277), Expect = 5e-24
Identities = 99/419 (23%), Positives = 214/419 (51%), Gaps = 46/419 (10%)
Query: 577 ERKERLESLNIQREK-----EEL-EQREA---ELQKVRKAEEERLRQEAKEREKERILQE 627
E ++ L ++ Q++K EEL ++R+A EL + +EE + AK +EK ++++
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 628 HEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQER 687
+ + V+E ++++ +L L P + + + L KE + + +
Sbjct: 236 EKSEIQLNVKELKRKLERAKL---------------LLPQQQLQAEADHLGKELQSVSAK 280
Query: 688 LKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHK 747
L+ Q ++ + + R + +E + + +E++I++ WE++ +E+ ++ + EK E +
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWR---QEEKIQE---WEEKIQEQEEKIREQEEKIREQE 334
Query: 748 NRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYY 807
+M R E +M K + EE + + EE++ E+ ++ R+ E ++
Sbjct: 335 EKMRRQEE-----MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
Query: 808 REKEEEEQRRAEEQMLKEREERERAERA--KREEELREYQERVKKLEEVERKKRQRELEI 865
+ E+E++R EE+ ++E+E+R+ E ++EE++RE +E K+ E E+K ++E +I
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE---KIREQEKKMWRQEEKI 446
Query: 866 EERERRREEERRLGDSSLSRKDSRWGDRDSEGTWR-KGPEADSEWRRGPPEKEWRRGEG- 923
E+E+ REEE+R + R++ + R+ E WR K + E R EK WR+ E
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEK--IREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 924 RDEDRSHRRDEERPRRLGDD-EDREPSLRPDDDRV-PRRGMDDDRGPRRGPEEDRFSRR 980
D++ R EE+ R + ++E +R ++++ + M ++ + G +E++ +
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Score = 111 bits (277), Expect = 5e-24
Identities = 99/419 (23%), Positives = 210/419 (50%), Gaps = 42/419 (10%)
Query: 480 LQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKP 539
LQ DH + L S A E+ + L E++ Q + K E +
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 540 AHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTI---EERKERLESLNIQREKE--EL 594
+EK + + + + ++ +++ + + + EE+ RLE + ++E++ EL
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Query: 595 EQREAELQKVR-----KAEEERLRQEAKEREKE-RILQEHEQIKKKTVRERLEQIKKTEL 648
E++ E +K+R + EEE++R++ K +E+E ++ ++ E+I+++ + R ++ K
Sbjct: 383 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
Query: 649 GAKAFKDIDIEDLEELDPDFIMAKQVEQL--------EKEKKELQERLKNQEKKIDYFER 700
K + I + E+ M +Q E++ +KEK QE+++ QE+K+
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKV----- 497
Query: 701 AKRLEEIPLIKSAYEEQRIKDMD--LWEQQEEERITTMQLEREKALEHKNRMSRMLEDRD 758
R EE K +E++I++ + +W Q+E+ R E+E+ + + R E+
Sbjct: 498 -WRQEE----KMHDQEEKIREQEEKMWRQEEKIR------EQEEKIREQEEKIREQEE-- 544
Query: 759 LFVMRLKAARQSVYEEKLKQFEE-RLAEERHNRLEERKRQRKEERRITYYREKEEEEQRR 817
+M+ + + EEK+++ E+ R EE+ EE+ R++KE+ R + E+EE+ R
Sbjct: 545 --MMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 602
Query: 818 AEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEER 876
+E+M++E+EE+ + K E+ + QE+ +K+ E K ++E+ + ++E + +E +
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 99.4 bits (246), Expect = 2e-20
Identities = 91/399 (22%), Positives = 203/399 (50%), Gaps = 27/399 (6%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL-QKVRKAEEERLRQEAKERE 620
++++ ++ + Q +E K ++ LN++ K +LE+ + L Q+ +AE + L +E +
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQ-LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 278
Query: 621 KERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKE 680
+ Q+++ + RL Q ++ ++ + K I++ EE + +++ + E++
Sbjct: 279 AKL----QAQVEENELWNRLNQQQEEKMWRQEEK---IQEWEEKIQE--QEEKIREQEEK 329
Query: 681 KKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL-E 739
+E +E+++ QE+ + E R +E + + + +R+++M +WE++E+ R ++ E
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM-MWEKEEKIRELEEKMHE 388
Query: 740 REKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRK 799
+EK E + + + R+ + + A+ EEK+++ EE++ E +E+K R+
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE------QEKKMWRQ 442
Query: 800 EERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKR 859
EE +I + EEE+R+ +E+M ++ E+ E R++E QE+++K E E+ R
Sbjct: 443 EE-KIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE--EKVWR 499
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
Q E ++ E+ RE+E ++ ++ R+ E R+ E E EK
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE----QEEKMGE 555
Query: 920 RGEGRDEDRSHRRDEERPRRLGDD-EDREPSLRPDDDRV 957
+ E E RR EE+ R + +++ +R ++++
Sbjct: 556 QEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
Score = 84.0 bits (206), Expect = 9e-16
Identities = 78/346 (22%), Positives = 177/346 (51%), Gaps = 37/346 (10%)
Query: 517 EQIRNQLTAM----SSVLAKALEVIKPAHILQEKEEQ-HQLAVTAYLKNSR-KEHQRILA 570
E+IR Q M + K ++ + ++ EKEE+ +L + K + +E + +
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMH 387
Query: 571 RRQTIEERKERLESLNIQREKEELEQREAEL----QKVRKAEEERLRQEAKEREKERILQ 626
++ I E++E+ + RE+E+ +++EA++ +K+R+ EE+ QE K +E +
Sbjct: 388 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH 447
Query: 627 EHEQIKKKTVRERLEQIKKTELGAKAFKDI--DIEDLEELDPDFIMAKQVEQLEKEKKEL 684
E E+I+++ R+ E++ + E + ++I E + E + ++V + E++ +
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 685 QERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKAL 744
+E+++ QE+K+ E R +E K +E++I++ + Q++EE++ E+E+ +
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEE---KIREQEEKIREQEEMMQEQEEKMG----EQEEKM 560
Query: 745 EHKNRMSRMLEDRDLFVMRLKAARQSV--YEEKLKQFEERLAEERHNRLEERKRQRKEER 802
+ + +M R E +++ ++ + EEK+ + EE++ E+ E+ ++ ++E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 803 RITYYREK---EEEEQRRAEEQM-------------LKEREERERA 832
++ EK +EE+ RR EE+M ++E +E A
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 56.2 bits (134), Expect = 2e-07
Identities = 48/226 (21%), Positives = 97/226 (42%), Gaps = 26/226 (11%)
Query: 1169 WRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERD 1228
WR K W EK + +EE + E+ E RE+E Q+ +K+ + R
Sbjct: 303 WRQEEKIQEWEEKIQEQEE--------KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 1229 RERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRD 1288
E ++E++ RR +E W + + + R+++++R+E + R+ +R++
Sbjct: 355 EEMMWEKEEKMRR-LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413
Query: 1289 LRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEE----RDPPRRVPPPALSRDRERDRD 1344
R+ +R + E++ + R+++++ E R+ +R + R E+ R+
Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473
Query: 1345 RE---REGEK----------EKASWRAEKDRESLRRTKNETDEDGW 1377
+E R+ EK E+ WR E+ E +E W
Sbjct: 474 QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW 519
Score = 54.3 bits (129), Expect = 8e-07
Identities = 42/202 (20%), Positives = 89/202 (44%), Gaps = 13/202 (6%)
Query: 1178 WREKEKAREES---WGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDR-ERDV 1233
W ++EK R + W + R EE W++E++ + E +K E+E R E +
Sbjct: 345 WEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 1234 DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
RE R+ ++ WR+ EE ++ R+ + R+ E+ ++ + R ++
Sbjct: 405 IREQEKRQEQEAKMWRQ---EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQ 461
Query: 1294 DRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEK 1353
+ RE+ W R+ +++ E++ R+ ++ + E+ E+E+
Sbjct: 462 EEMWRQEEKIREQEEIW-----RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
Query: 1354 ASWR-AEKDRESLRRTKNETDE 1374
WR EK RE + + + ++
Sbjct: 517 KMWRQEEKIREQEEKIREQEEK 538
Score = 54.3 bits (129), Expect = 8e-07
Identities = 43/224 (19%), Positives = 98/224 (43%), Gaps = 35/224 (15%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERE--RDRERDVDR 1235
WR++EK RE+ + R E++ W +E++ + REE + + E R E+ ++
Sbjct: 419 WRQEEKIREQE----EKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 474
Query: 1236 EDRFR-----------RPRDEGGWRRGP----------AEESSSWRDSSRRDDRDRDDRR 1274
E+ +R R ++E WR+ +E W R++++ R+
Sbjct: 475 EEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMW----RQEEKIREQEE 530
Query: 1275 RERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDR---KDDRVEERDPPRRVP 1331
+ R+ +RE+ ++ +++ + + +E RR +++ +++++ E+ R
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 1332 PPALSRDRERDRDRER-EGEKEKASWRAEKDRESLRRTKNETDE 1374
+ E+ R++E E+E+ W E+ E +E
Sbjct: 591 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Score = 53.5 bits (127), Expect = 1e-06
Identities = 44/211 (20%), Positives = 103/211 (48%), Gaps = 27/211 (12%)
Query: 1178 WREKEKAR---EESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVD 1234
W ++EK R E W + R EE+ ++EK R+++ + R+E +K E+E+ +E++
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEK-RQEEEKIREQEKRQEQEAK 417
Query: 1235 --REDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDR---DDRRRERDD----RRDLRE 1285
R++ R ++E + +E WR + ++++ +++R+E+++ +RE
Sbjct: 418 MWRQEEKIREQEE----KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473
Query: 1286 RRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDR 1345
+ ++ +++ + ++E WR+ + D + R+ + + R E+ R++
Sbjct: 474 QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEK-----MWRQEEKIREQ 528
Query: 1346 EREGEKEKASWRAEKDRESLRRTKNETDEDG 1376
E EK + EK RE + + ++ G
Sbjct: 529 E-----EKIREQEEKIREQEEMMQEQEEKMG 554
Score = 43.9 bits (102), Expect = 0.001
Identities = 35/191 (18%), Positives = 89/191 (46%), Gaps = 22/191 (11%)
Query: 1178 WREKEKA---------REESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERD 1228
WR+KEK E+ W + EE+ ++E++ R + E + E+ R+
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQE---EKIRE 534
Query: 1229 RERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRR-DDRDRDDRRRERDDRRDLRERR 1287
+E + ++ + ++E + G EE ++ RR +++ R+ + R+ + +RE+
Sbjct: 535 QEEKIREQEEMMQEQEE---KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE 591
Query: 1288 DL---RDDRDRRGPPLRSEREEVSSWRRADD--RKDDRVEERDPPRRVPPPALSRDRERD 1342
+ ++++ R + E+EE W + + ++++++E++ R + R
Sbjct: 592 EKIWEQEEKIREQEEMMQEQEE-KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRL 650
Query: 1343 RDREREGEKEK 1353
R +E + ++ +
Sbjct: 651 RQQEEKMQEHQ 661
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 115 bits (289), Expect = 2e-25
Identities = 126/519 (24%), Positives = 246/519 (47%), Gaps = 75/519 (14%)
Query: 480 LQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKP 539
LQ DH + L S A E+ + L E++ Q + K
Sbjct: 263 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK------- 315
Query: 540 AHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLN-IQREKEELEQRE 598
+QE+EE+ + + R++ +++ + + + E++E++ + EKEE +R+
Sbjct: 316 ---IQEQEEK----IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368
Query: 599 AEL-----QKVRKAEEERLRQEAKEREKERILQEHEQIK----KKTVRERL-EQIKKTEL 648
E+ +K+R+ EE +E K RE E + E E+I+ K+ E++ EQ K+ E
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 428
Query: 649 GAKAFKDID-IEDLEEL--DPDFIMAKQVEQL-------EKEKKELQERLKNQEKKIDYF 698
AK ++ + I + EE + + M +Q E++ E+EK++ QE + QE+KI
Sbjct: 429 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQ 488
Query: 699 ERAKRLEEIPLIKSAYEEQRIKDMD--LWEQQEEERITTMQLEREKALEHKNRMSRMLED 756
E R +E K +E++I+ + +W Q+E+ R + EK E + +M R E
Sbjct: 489 EEIWRQKE----KMHEQEEKIRKQEEKVWRQEEKIRE-----QEEKIREQEEKMWRQEE- 538
Query: 757 RDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEER------RITYYREK 810
+++ + EE+ +E++ EE + +E K R+EE+ ++ EK
Sbjct: 539 ------KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Query: 811 --EEEEQRRAEEQMLKEREERERAERAK---REEELREYQERVKKLEEV-----ERKKRQ 860
E+EE+R+ +E+ + ++EE+ R + K +EE++RE +E++++ EE+ E+ Q
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 861 RELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRR 920
E E+ E+ +E+E + ++ R+ E R+ E E EK W +
Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQE----QEEKMWEQ 708
Query: 921 GEGRDEDRSHRRDEERPRRLGDDE--DREPSLRPDDDRV 957
E E +++E R +++ ++E LR ++++
Sbjct: 709 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
Score = 110 bits (274), Expect = 1e-23
Identities = 105/516 (20%), Positives = 238/516 (46%), Gaps = 71/516 (13%)
Query: 557 YLKNSRKEHQRILAR--RQTI--EERKERLESLN-----IQREKEELEQREAELQKVRKA 607
Y++ KE + R TI EE KE+ L ++ EK E++ EL++ +
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 608 EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPD 667
+ L Q+ + E + + +E + + K Q+++ EL + + ++ +
Sbjct: 254 AKLLLPQQQLQAEADHLGKELQSVSAKLQA----QVEENELWNRL-------NQQQEEKM 302
Query: 668 FIMAKQVEQLEKEKKELQERLKNQEKKI-DYFERAKRLEEIPLIKSAYEEQRIKDMDLWE 726
+ +++++ E++ +E +E+++ QE+KI + E+ +R EE+ K E+ R ++ +WE
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE--EKMRRQEEMMWE 360
Query: 727 QQEE-ERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE 785
++E+ R M E+E+ + + M E++ + ++ + E++ K+ EE
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
Query: 786 ERHNRLEERKRQRKEERRITYYREK---------------------EEEEQRRAEEQMLK 824
E+ R E+ + ++E +I EK EEE+R+ +E+M +
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 825 EREE-RERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSL 883
+ E+ E+ E +++E++ E +E+++K EE ++ ++ E EE+ R +EE+ + +
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Query: 884 SRKDSRWGD----RDSEGTW---RKGPEADSEWR-----RGPPEKEWRRGEGRDEDRSHR 931
++ W + + E W ++ + D WR R EK WR+ E E R
Sbjct: 541 REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKR 600
Query: 932 RDEE-----RPRRLGDDEDR----EPSLRPDDDRV-PRRGMDDDRGPRRGPEEDRF---S 978
+++E + ++ + E++ E +R ++++ + M ++ + G +E++
Sbjct: 601 QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
Query: 979 RRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADD 1014
+ + + WR + R + E R ++
Sbjct: 661 EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEE 696
Score = 108 bits (269), Expect = 5e-23
Identities = 81/319 (25%), Positives = 176/319 (55%), Gaps = 41/319 (12%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
+ R+E + + + + I E++E I R+KE++ ++E +K+RK EE+ RQE K
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEE------IWRQKEKMHEQE---EKIRKQEEKVWRQEEKI 519
Query: 619 REKERILQEHEQI---KKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVE 675
RE+E ++E E+ +++ +RE+ E ++ E + K + E +E + M +Q E
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDK--MWRQEE 577
Query: 676 QLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITT 735
++ +E +E++ QE+KI E ++ +E + K +E++I++ + Q++EE+I
Sbjct: 578 KI----REQEEKVWRQEEKIREQEEKRQEQEEKMWK---QEEKIREQEEKIQEQEEKIR- 629
Query: 736 MQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERK 795
E+E+ + + M++ E++ EEK+ + EE++ E+ + +
Sbjct: 630 ---EQEEKIREQEEMTQEQEEK-----------MGEQEEKMCEQEEKMQEQEETMWRQEE 675
Query: 796 RQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVE 855
+ R++E++I +E+EE+ R +E+M++E+EE+ + K E+ + QE+ +K+ E
Sbjct: 676 KIREQEKKI-----REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Query: 856 RKKRQRELEIEERERRREE 874
K ++E+ + ++E + +E
Sbjct: 731 EKMWEQEVRLRQQEEKMQE 749
Score = 79.3 bits (194), Expect = 2e-14
Identities = 117/689 (16%), Positives = 281/689 (40%), Gaps = 109/689 (15%)
Query: 674 VEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKS-AYEEQRIKDMDLWEQQEEER 732
V+QLE E ++L RL + K E+A K+ Y E+ K+ D +
Sbjct: 153 VKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRN 212
Query: 733 ITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLE 792
T + +EK + + ++ + ++ + +K ++ + KL +++L E + +
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGK 272
Query: 793 E------RKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846
E + + + EE + +++EE+ +E+ ++E EE+ + ++EE++RE +E
Sbjct: 273 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ----EQEEKIREQEE 328
Query: 847 RVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEAD 906
++++ EE R++ + E EE+ RR+EE + + R++ E W K
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE--------EMMWEK----- 375
Query: 907 SEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDR 966
E R E W + EE+ R L + + +R +++
Sbjct: 376 EEKMRRQEEMMWEK-------------EEKIRELEEKMHEQEKIREQEEK---------- 412
Query: 967 GPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPR-RIADEDRGNWRHADDDRPPRRGLDED 1025
R+ E+ R + + + WR + R +I ++++ WR + + +E+
Sbjct: 413 --RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 1026 RGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDD 1085
+R ++ + ++ WR + + + R ++
Sbjct: 471 -------------KRQEQEEMWRQEEKIHEQEEIWRQKEK-------MHEQEEKIRKQEE 510
Query: 1086 D--RGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNM 1143
R + + + R + + + WR + + E+++
Sbjct: 511 KVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEK------ 564
Query: 1144 DDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREW 1203
R+ +D+ R+ + R + WR++EK RE+ E R +E +
Sbjct: 565 ------RQEQEDKMWRQEEKIREQEEKV------WRQEEKIREQE-----EKRQEQEEKM 607
Query: 1204 DREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSS 1263
+++E+ R+ +++ + + E+ R++E + ++ + ++E + G EE ++
Sbjct: 608 WKQEEKIREQEEKIQEQE--EKIREQEEKIREQEEMTQEQEE---KMGEQEEKMCEQEEK 662
Query: 1264 RRDDRDRDDRRRE--RDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADD--RKDD 1319
++ + R+ E R+ + +RE ++++ R + E+EE W + + +++
Sbjct: 663 MQEQEETMWRQEEKIREQEKKIRE----QEEKIREQEEMMQEQEE-KMWEQEEKMCEQEE 717
Query: 1320 RVEERDPPRRVPPPALSRDRERDRDRERE 1348
+++E++ R + R R +E +
Sbjct: 718 KMQEQEEKMRRQEEKMWEQEVRLRQQEEK 746
Score = 58.9 bits (141), Expect = 3e-08
Identities = 40/203 (19%), Positives = 93/203 (45%), Gaps = 10/203 (4%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREW-DREKERDRDNQDREENDK---DPERERDRERDV 1233
WR+KEK E+ + R EE+ W EK R+++ + RE+ +K E+ R++E
Sbjct: 492 WRQKEKMHEQE----EKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMW 547
Query: 1234 DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
E++ + +E WR + +++ R+E R +R++ +
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607
Query: 1294 DRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRERE-GEKE 1352
++ +R + E++ +++++ E++ + + E+ ++E + E+E
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 1353 KASWR-AEKDRESLRRTKNETDE 1374
+ WR EK RE ++ + + ++
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEK 690
Score = 58.5 bits (140), Expect = 4e-08
Identities = 44/211 (20%), Positives = 96/211 (45%), Gaps = 17/211 (8%)
Query: 1178 WREKEKAREES---WGPPRESRPSEEREWDREK-----ERDRDNQD--REENDKDPERER 1227
W ++EK R + W + R EE W++E+ E Q+ RE+ +K E E+
Sbjct: 359 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 418
Query: 1228 DRERDVDREDRFRRPRDEGGWRRGP----AEESSSWRDSSRRDDRDR---DDRRRERDDR 1280
RE++ +E + R E R +E WR + ++++ +++R+E+++
Sbjct: 419 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
Query: 1281 RDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
E+ +++ R+ + + E++ R+++++ E++ R + R E
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEE 538
Query: 1341 RDRDREREGEKEKASWRAEKDRESLRRTKNE 1371
+ R++E +E+ EK E +R + E
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Score = 56.6 bits (135), Expect = 2e-07
Identities = 106/656 (16%), Positives = 253/656 (38%), Gaps = 61/656 (9%)
Query: 739 EREKALEHKNRMSRMLED-----RDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEE 793
E++ + +H+ + R LE R L + + Y + + E A + +RL +
Sbjct: 110 EQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 169
Query: 794 RKRQRKEERRITYYREKEEEEQRRAEEQMLKERE--ERERAERAKREEELREYQERVK-K 850
+ E + ++++ R E++ KER+ E +EEL+E +++ K
Sbjct: 170 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 229
Query: 851 LEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWR 910
L+ VE +K + +L ++E +R+ E + L + ++ ++ + K E
Sbjct: 230 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEE-- 287
Query: 911 RGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRR 970
+ W R + E++ R++E+ +++E +R ++++ + R
Sbjct: 288 ----NELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 971 GPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADD----DRPPRRGLDEDR 1026
E++ RR + W + R + E R ++ R L+E
Sbjct: 344 MWEKEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400
Query: 1027 GSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDD 1086
E R+ + R + + E WR + R + + ++
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKR-QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Query: 1087 RGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADD-DRIPRRGAEDDRGPWRNMDD 1145
+ + ++ R+ ++ + + WR + + + + WR +
Sbjct: 460 IHEQEKIREEE-KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 1146 DRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKARE--ESWGPPRESRPSEEREW 1203
R + + R ++ WR++EK RE E W E +E+ W
Sbjct: 519 IR-----EQEEKIREQEEKM------------WRQEEKIREQEEMWRE-EEKMHEQEKIW 560
Query: 1204 DREKERDR-DNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDS 1262
+ EK +++ D R+E E+ R++E V R++ R ++E + +E W+
Sbjct: 561 EEEKRQEQEDKMWRQE-----EKIREQEEKVWRQEEKIREQEE----KRQEQEEKMWKQE 611
Query: 1263 SR---RDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDD 1319
+ ++++ ++ + R+ +RE+ ++ +++ + + + E++ +++
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK---MGEQEEKMCEQEEKMQEQEE 668
Query: 1320 RVEERDPPRRVPPPALSRDRERDRDRERE-GEKEKASWRAEKDRESLRRTKNETDE 1374
+ ++ R + E+ R++E E+E+ W E+ E +E
Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Score = 56.2 bits (134), Expect = 2e-07
Identities = 43/207 (20%), Positives = 93/207 (44%), Gaps = 16/207 (7%)
Query: 1180 EKEKAREESWGPPRESRPSEEREWDREKERDRDNQDR-EENDKDPERERDR--ERDVDRE 1236
++EK +EE +E R +E + R++E+ R+ +++ E +K R+ ++ E++ RE
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 1237 DRFRRPRDEGGWRRGPA--EESSSWRDSSRRDDRDRDDRRRE----RDDRRDLRERRDLR 1290
+ R+ ++E WR+ E+ WR + +++ R++E R + + + +R
Sbjct: 469 EEKRQEQEEM-WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 1291 DDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGE 1350
+ ++ RE+ WR + + + R+ + R E+ R E
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR------E 581
Query: 1351 KEKASWRAEKDRESLRRTKNETDEDGW 1377
+E+ WR E+ + E +E W
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMW 608
Score = 55.5 bits (132), Expect = 4e-07
Identities = 49/235 (20%), Positives = 100/235 (42%), Gaps = 29/235 (12%)
Query: 1169 WRPLVKPGGWREKEKAREESWGPPRES--------RPSEEREWDREKERDRDNQDREEND 1220
WR K W EK + +EE E R EE W++E++ R Q+ +
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR--QEEMMWE 360
Query: 1221 KDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDR 1280
K+ + R E ++E++ RR ++E W + + + R+++++R+E +
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRR-QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419
Query: 1281 RDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEE----RDPPRRVPPPALS 1336
R+ +R++ R+ +R + E++ + R+++++ E R+ +R +
Sbjct: 420 REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 479
Query: 1337 RDRERDRDRE---REGEK-----------EKASWRAEKDRESLRRTKNETDEDGW 1377
R E+ ++E R+ EK E+ WR E+ E +E W
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Score = 42.0 bits (97), Expect = 0.004
Identities = 25/91 (27%), Positives = 54/91 (59%), Gaps = 8/91 (8%)
Query: 543 LQEKEE---QHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREK--EELEQR 597
+QE+EE + + + K R++ ++I + + ++E++E++ Q EK E+ E+
Sbjct: 663 MQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE---QEEKMCEQEEKM 719
Query: 598 EAELQKVRKAEEERLRQEAKEREKERILQEH 628
+ + +K+R+ EE+ QE + R++E +QEH
Sbjct: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 115 bits (288), Expect = 3e-25
Identities = 95/415 (22%), Positives = 217/415 (52%), Gaps = 47/415 (11%)
Query: 520 RNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERK 579
+ QL A + L K L+ + LQ + E+++L + + ++++ +++ + + I+E +
Sbjct: 321 QQQLQAEADHLGKELQSVSAK--LQAQVEENEL----WNRLNQQQEEKMWRQEEKIQEWE 374
Query: 580 ERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQI---KKKTV 636
E+ IQ ++E++ ++E +K+R+ EE+ RQE EKE ++ E++ K++ +
Sbjct: 375 EK-----IQEQEEKIREQE---EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 637 RERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKID 696
R + E + + E E + EL+ +++ + E EK++ +E+++ QEK+ +
Sbjct: 427 RRQEEMMWEKE-----------EKIRELEEKMHEQEKIREQE-EKRQEEEKIREQEKRQE 474
Query: 697 YFERAKRLEEIPLIKSAYEEQRIKDMD--LWEQQEEERITTMQLEREKALEHKN---RMS 751
+ R EE K +E++I++ + +W Q+E+ E EK E + +
Sbjct: 475 QEAKMWRQEE----KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 752 RMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREK- 810
++ E +++ + K Q EEK+++ EE++ + ++ ++ R++E ++ EK
Sbjct: 531 KIREQEEIWRQKEKIHEQ---EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 811 -EEEEQRRAEEQMLKEREERERAERAK---REEELREYQERVKKLEEVERKKRQRELEIE 866
E+EE+ R +E+ ++E+EE + + K +EE++ E +E++++ EE R++ ++ E E
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Query: 867 ERERRREEERRLGDSSLSRKDSR-WGDRDSEGTWRKGPEADSEWRRGPPEKEWRR 920
++ R +EE+ R + + ++ + W + + + E R EK W +
Sbjct: 648 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Score = 112 bits (279), Expect = 3e-24
Identities = 97/396 (24%), Positives = 207/396 (52%), Gaps = 41/396 (10%)
Query: 516 SEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQ----HQLAVTAYLKNSRKEHQRILAR 571
++ + +L ++S+ L +E + + L +++E+ + + + + +++ ++I +
Sbjct: 328 ADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ 387
Query: 572 RQTIEERKERLESLN-IQREKEELEQREAEL-----QKVRKAEEERLRQEAKEREKERIL 625
+ I E++E++ + EKEE +R+ E+ +K+R+ EE +E K RE E +
Sbjct: 388 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 447
Query: 626 QEHEQIK----KKTVRERL-EQIKKTELGAKAFKDID-IEDLEEL--DPDFIMAKQVEQL 677
E E+I+ K+ E++ EQ K+ E AK ++ + I + EE + + M +Q E++
Sbjct: 448 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Query: 678 -------EKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQE- 729
E+EK++ QE + QE+KI E R +E I E+ R ++ +W Q+E
Sbjct: 508 HEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE--KIHEQEEKIRKQEEKMWRQEEK 565
Query: 730 ----EERITTMQLE---REKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEER 782
EE+I + + +E+ + + R E++ +R + EEK+ + EE+
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEK----IREQEEMTQEQEEKMGEQEEK 621
Query: 783 LAEERHNRLEERKRQRKEERRITYYREK--EEEEQRRAEEQMLKEREERERAERAKREEE 840
+ E+ E+ ++ R++E +I +K E+EE+ R +E+M++E+EE+ + K E+
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681
Query: 841 LREYQERVKKLEEVERKKRQRELEIEERERRREEER 876
+ QE+ +K+ E K ++E+ + ++E + +E +
Sbjct: 682 EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Score = 107 bits (266), Expect = 1e-22
Identities = 107/420 (25%), Positives = 209/420 (49%), Gaps = 64/420 (15%)
Query: 563 KEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKE 622
KE Q + A+ Q E E LN Q+E++ Q E K+++ EE+ QE K RE+E
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE----KIQEWEEKIQEQEEKIREQE 388
Query: 623 RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQL-EKEK 681
++E E+ +R + E + + E + +++ E E+ M +Q E + EKE+
Sbjct: 389 EKIREQEE----KMRRQEEMMWEKEEKMRRQEEMMWEKEEK------MRRQEEMMWEKEE 438
Query: 682 K--ELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLE 739
K EL+E++ QEK + E+ + E+I E+++ ++ +W Q+E+ R +
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKI----REQEKRQEQEAKMWRQEEKIRE-----Q 489
Query: 740 REKALEHKNRMSRMLEDRDLFVMRLKAARQSVYE-EKLKQFEERLAEERHNRLEERKRQR 798
EK E + +M R E ++E EK+++ E+R +E R EE+ R++
Sbjct: 490 EEKIREQEEKMWRQEE--------------KIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535
Query: 799 KEERRITYYREKEEEEQRRAEEQMLKEREE--------RERAERAKREEE--------LR 842
+E R ++EE+ R+ EE+M ++ E+ RE+ E+ R+EE +R
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595
Query: 843 EYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKG 902
E +E++++ EE+ +++ ++ E EE+ +EE+ + + + R++ + R+ E R+
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK--IREQEKKIREQ 653
Query: 903 PE---ADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDE--DREPSLRPDDDRV 957
E E + EK W + E E +++E R +++ ++E LR ++++
Sbjct: 654 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Score = 102 bits (255), Expect = 2e-21
Identities = 90/411 (21%), Positives = 210/411 (51%), Gaps = 30/411 (7%)
Query: 480 LQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKP 539
LQ DH + L S A E+ + L E++ Q + K E +
Sbjct: 324 LQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 383
Query: 540 AHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERL---ESLNIQREKE--EL 594
+EK + + + + ++ +++ + + + E++E++ E + ++E++ EL
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 443
Query: 595 EQREAELQKVR-----KAEEERLRQEAKEREKE-RILQEHEQIKKKTVRERLEQIKKTEL 648
E++ E +K+R + EEE++R++ K +E+E ++ ++ E+I+++ + R ++ K
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 649 GAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK--ELQERLKNQEKKI-DYFERAKRLE 705
K + I + E+ M +Q E++ ++++ +E++ QE+KI E+ R E
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQE 563
Query: 706 EIPLIKSAYEEQRIKDMD--LWEQQEEERITTMQL-EREKALEHKNRMSRMLEDRDLFVM 762
E K +E++I++ + +W Q+E+ R ++ E+E+ + + M++ E++ M
Sbjct: 564 E----KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK----M 615
Query: 763 RLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQM 822
+ + EEK+++ EE++ + E+ K+ R++E +I +E+EE + +E+
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI-----REQEEMMQEQEEK 670
Query: 823 LKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRRE 873
+ E+EE+ + K +E+ + + + +K+ E E + RQ+E +++E + E
Sbjct: 671 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 96.7 bits (239), Expect = 1e-19
Identities = 82/396 (20%), Positives = 194/396 (48%), Gaps = 21/396 (5%)
Query: 575 IEERKERLESLNIQREK-----EELEQREAELQ-KVRKAEEERLRQEAKEREKERILQEH 628
IEE + ++L+++ + EEL+++ A+LQ K++ E E+ + +E +R L+
Sbjct: 256 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER- 314
Query: 629 EQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERL 688
K + ++ Q + LG K + + + +++ + + + +Q E++ +E++
Sbjct: 315 ---AKLLLPQQQLQAEADHLG-KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI 370
Query: 689 KNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEE-ERITTMQLEREKALEHK 747
+ E+KI E R +E I+ E+ R ++ +WE++E+ R M E+E+ + +
Sbjct: 371 QEWEEKIQEQEEKIREQE-EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 429
Query: 748 NRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYY 807
M E++ + ++ + E++ K+ EE E+ R E+ + ++E +I
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Query: 808 REK--EEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEI 865
EK E+EE+ +E+ + E+E+ E+ + +EE+ +E++++ EE+ R+K + +
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK--IHE 547
Query: 866 EERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPE-ADSEWRRGPPEKEWRRGEGR 924
+E + R++EE+ E WR+ + + E + E++ R E
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607
Query: 925 DEDRSHRRDEERPRRLGDDE---DREPSLRPDDDRV 957
+++ + E+ + +E ++E +R ++++
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Score = 93.6 bits (231), Expect = 1e-18
Identities = 98/435 (22%), Positives = 215/435 (49%), Gaps = 60/435 (13%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREK 621
+ HQ A R+ +E + + L Q+ + ++ ++ V++ E E ++ +
Sbjct: 173 KASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQ-HAVKQLEGEARDLISRLHDS 231
Query: 622 ERILQEHEQI------KKKTVRERLEQIKKTE--LGAKAFKDIDIEDLEELDPDFIMAKQ 673
+ E EQ +KK +E++ K L + +++ I D E + + + ++
Sbjct: 232 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT-ITDEELKEKNAKLQEK 290
Query: 674 VEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERI 733
++ +E EK E+Q +K ++K+ ERAK L +P ++Q + D ++ +
Sbjct: 291 LQLVESEKSEIQLNVKELKRKL---ERAKLL--LP------QQQLQAEADHLGKELQSVS 339
Query: 734 TTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN-RLE 792
+Q + E+ E NR+++ E++ M + + +EEK+++ EE++ E+ R +
Sbjct: 340 AKLQAQVEEN-ELWNRLNQQQEEK----MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394
Query: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERA---KREEELREYQERVK 849
E K +R+EE E+EE+ R +E+M+ E+EE+ R + ++EE++RE +E++
Sbjct: 395 EEKMRRQEEMM------WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 850 KLEEV--ERKKRQRELEIEERERRREEERRL----------------GDSSLSRKDSRWG 891
+ E++ + +KRQ E +I E+E+R+E+E ++ + + R++ +
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 892 DRDSEGTWRKGPEADSEWRRGPPEKE----WRRGE--GRDEDRSHRRDEERPRRLGDDED 945
+++ K E + WR+ +E WR+ E E++ +++E+ R+ D
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568
Query: 946 REPSLRPDDDRVPRR 960
+E +R +++V R+
Sbjct: 569 QEEKIREQEEKVWRQ 583
Score = 87.4 bits (215), Expect = 8e-17
Identities = 74/337 (21%), Positives = 175/337 (51%), Gaps = 24/337 (7%)
Query: 517 EQIRNQLTAM----SSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRK--EHQRILA 570
E+IR Q M + K ++ + ++ EKEE+ + + K E + +
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 571 RRQTIEERKERLESLNIQREKEELEQREAEL----QKVRKAEEERLRQEAKEREKERILQ 626
++ I E++E+ + RE+E+ +++EA++ +K+R+ EE+ QE K +E +
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 627 EHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKEL-- 684
E E+I+++ R+ E++ + E + ++I + + + + + KQ E++ ++++++
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568
Query: 685 -QERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERI----TTMQLE 739
+E+++ QE+K+ E R +E K +E++I++ + Q++EE++ M +
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEE---KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Query: 740 REKALEHKNRMSRMLEDRDLFVMRLKAARQSV--YEEKLKQFEERLAEERHNRLEERKRQ 797
EK E + +M R E +++ + + EE +++ EE++ E+ E+ ++
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685
Query: 798 RKEERRITYYREK--EEEEQRRAEEQMLKEREERERA 832
+++E ++ EK E+E + R +E+ ++E +E A
Sbjct: 686 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 58.2 bits (139), Expect = 6e-08
Identities = 45/203 (22%), Positives = 92/203 (45%), Gaps = 14/203 (6%)
Query: 1178 WREKEKAREES---WGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDR-ERDV 1233
W ++EK R + W + R EE W++E++ + E +K E+E R E +
Sbjct: 406 WEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 465
Query: 1234 DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
RE R+ ++ WR+ EE ++ R+ ++ R+ E+ ++ + R ++
Sbjct: 466 IREQEKRQEQEAKMWRQ---EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ 522
Query: 1294 DRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRERE-GEKE 1352
+ RE+ W R+ +++ E++ R + R E+ D+E + E+E
Sbjct: 523 EEMWRQEEKIREQEEIW-----RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577
Query: 1353 KASWR-AEKDRESLRRTKNETDE 1374
+ WR EK RE + + + ++
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEK 600
Score = 52.0 bits (123), Expect = 4e-06
Identities = 47/222 (21%), Positives = 98/222 (44%), Gaps = 26/222 (11%)
Query: 1178 WREKEKARE-ESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDRE 1236
WR++EK +E E +E + E+ E RE+E Q+ +K+ + R E ++E
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 423
Query: 1237 DRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRD-- 1294
++ RR ++E W + + + R+++++R+E + +RE+ ++
Sbjct: 424 EKMRR-QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE---KIREQEKRQEQEAKM 479
Query: 1295 -RRGPPLRSEREEVSSWRRADDRKDDRVEE----RDPPRRVPPPALSRDRERDRDRE--- 1346
R+ +R + E++ R+++++ E R+ +R + R E+ R++E
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 1347 REGEK-----------EKASWRAEKDRESLRRTKNETDEDGW 1377
R+ EK E+ WR E+ E +E W
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Score = 50.4 bits (119), Expect = 1e-05
Identities = 40/200 (20%), Positives = 98/200 (49%), Gaps = 15/200 (7%)
Query: 1180 EKEKAREESWGPPRESRPSEEREWDREKERDRDNQD--REENDKD-PERERDRERDVDRE 1236
++EK +EE +E R +E + R++E+ R+ ++ RE+ +K + E+ E++ RE
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIRE 515
Query: 1237 DRFRRPRDEGGWRRGPA--EESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRD 1294
+ R+ ++E WR+ E+ WR + +++ R++E + R+ + D +
Sbjct: 516 EEKRQEQEEM-WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEE---KMWRQEEKMHDQEE 571
Query: 1295 RRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKA 1354
+ +R + E+V WR+ + ++ + R+ ++ + ++ E+E + +
Sbjct: 572 K----IREQEEKV--WRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Query: 1355 SWRAEKDRESLRRTKNETDE 1374
+ ++ E +RR + + E
Sbjct: 626 EEKMQEQEEKMRRQEEKIRE 645
Score = 45.4 bits (106), Expect = 4e-04
Identities = 42/197 (21%), Positives = 93/197 (47%), Gaps = 26/197 (13%)
Query: 1178 WREKEKAR--EESW-------GPPRESRPSEEREW-DREKERDRDNQDREENDK---DPE 1224
WR++EK R EE W + R EE+ W EK D++ + RE+ +K E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 1225 RERDRERDV-DREDRFRRPRD---EGGWRRGPAEESSSWRDSSRRDDRDRDDRRRE--RD 1278
+ R++E + ++E++ R + E + G EE ++ ++ ++ R+ E R+
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645
Query: 1279 DRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADD--RKDDRVEERDPPRRVPPPALS 1336
+ +RE ++++ R + E+EE W + + ++++++E++ R +
Sbjct: 646 QEKKIRE----QEEKIREQEEMMQEQEE-KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 700
Query: 1337 RDRERDRDREREGEKEK 1353
R R +E + ++ +
Sbjct: 701 EQEVRLRQQEEKMQEHQ 717
Score = 40.4 bits (93), Expect = 0.012
Identities = 29/153 (18%), Positives = 69/153 (45%), Gaps = 16/153 (10%)
Query: 1237 DRFRRPRDEGGWRRGPAEESSSWRDS-SRRDDRDRDDRRRERDDRRDLRERRDL---RDD 1292
+R + ++E WR+ E+ W + ++++ R+ + R+ +R + ++ +++
Sbjct: 353 NRLNQQQEEKMWRQ--EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410
Query: 1293 RDRRGPPLRSEREEVSSWRRADD---RKDDRVEERDPPRRVPPPALSRDRERD-----RD 1344
+ RR + E+EE RR ++ K++++ E + ++ +R R+
Sbjct: 411 KMRRQEEMMWEKEE--KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 468
Query: 1345 REREGEKEKASWRAEKDRESLRRTKNETDEDGW 1377
+E+ E+E WR E+ E +E W
Sbjct: 469 QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 112 bits (280), Expect = 2e-24
Identities = 85/329 (25%), Positives = 174/329 (52%), Gaps = 36/329 (10%)
Query: 563 KEHQRILARRQTIEERKERLESLNIQ------REKEELEQREAELQ----KVRKAEEERL 612
KE Q + A+ Q E E LN Q R++E++++RE ++Q K+R+ EE+
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMR 319
Query: 613 RQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAK 672
RQE EKE ++ E++ + E+ E+I+ EL K + I + EE + +
Sbjct: 320 RQEEMMWEKEEKMRRQEEM----MWEKEEKIR--ELEEKMHEQEKIREQEEKRQEEEKIR 373
Query: 673 QVEQLEKEKKEL---QERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQE 729
+ E+ ++++ ++ +E+++ QE+KI E+ +++ E+ ++ +WEQ+E
Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIR--------EQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 730 E--ERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEER 787
E E+ M+ + EK E + ++ E +R + EEK+ + E ++ E+
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEK-----IREQEEMMQEQEEKMGEQEGKMCEQE 480
Query: 788 HNRLEERKRQRKEERRITYYREK--EEEEQRRAEEQMLKEREERERAERAKREEELREYQ 845
E+ ++ R++E +I +K E+EE+ R +E+M++E+EE+ + K E+ + Q
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 846 ERVKKLEEVERKKRQRELEIEERERRREE 874
E+ +K+ E K R++E+ + ++E + +E
Sbjct: 541 EQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 105 bits (262), Expect = 3e-22
Identities = 90/394 (22%), Positives = 206/394 (52%), Gaps = 34/394 (8%)
Query: 575 IEERKERLESLNIQREK-----EELEQREAELQ-KVRKAEEERLRQEAKEREKERILQEH 628
IEE + ++L+++ + EEL+++ A+LQ K++ E E+ + +E +R L+
Sbjct: 183 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERA 242
Query: 629 EQI-KKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQER 687
+ + ++ ++ + + K A +E+ E + + +Q E++ ++++++QER
Sbjct: 243 KLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR--LNQQQEEKMWRQEEKIQER 300
Query: 688 ---LKNQEKKI-DYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL-EREK 742
++ QE+KI + E+ +R EE+ K E+ R ++ +WE++E+ R ++ E+EK
Sbjct: 301 EEKIQEQEEKIREQEEKMRRQEEMMWEKE--EKMRRQEEMMWEKEEKIRELEEKMHEQEK 358
Query: 743 ALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEER 802
E + + + R+ + + A+ EEK+++ EE++ E+ E+ ++ ++E
Sbjct: 359 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 418
Query: 803 RITYYREK--EEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQ 860
++ E+ E+EE+ R +E+ ++E+E++ R + K E+ QE+ +K+ E E K +
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 861 RELEIEERE---RRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKE 917
+E +++E+E RR+EE+ R + + ++ + +++ E + EK
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE-------------EMMQEQEEKM 525
Query: 918 WRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLR 951
W + E E +++E R +++ RE +R
Sbjct: 526 WEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVR 559
Score = 101 bits (252), Expect = 4e-21
Identities = 87/372 (23%), Positives = 184/372 (49%), Gaps = 49/372 (13%)
Query: 593 ELEQREAELQKVRKAEEERLRQEAKERE-------KERILQEHEQIKKKTVRERLEQIK- 644
ELEQ + + +K + + + KER+ + I E + K ++E+L+ ++
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 223
Query: 645 ---KTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERA 701
+ +L K K +E + L P + + + L KE + + +L+ Q ++ + + R
Sbjct: 224 EKSEIQLNVKELKR-KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRL 282
Query: 702 KRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFV 761
+ +E + + +E++I++ + Q++EE+I E+E+ + + M E++
Sbjct: 283 NQQQEEKMWR---QEEKIQEREEKIQEQEEKIR----EQEEKMRRQEEMMWEKEEK---- 331
Query: 762 MRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYRE------------ 809
MR + EEK+++ EE++ E+ R +E KRQ +E+ R R+
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 810 -KEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEER 868
+E+EE+ R +E+M++E+EE+ + K E+ E QE+ +K+ E K R++E +I E+
Sbjct: 392 IREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQ 451
Query: 869 ERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEG--RDE 926
E + E+ + + ++ + G+++ G + E + E++ RR E R++
Sbjct: 452 EEKIREQEEM----MQEQEEKMGEQE-------GKMCEQEAKMQEQEEKMRRQEEKIREQ 500
Query: 927 DRSHRRDEERPR 938
++ R EE+ R
Sbjct: 501 EKKIREQEEKIR 512
Score = 101 bits (252), Expect = 4e-21
Identities = 96/405 (23%), Positives = 204/405 (50%), Gaps = 60/405 (14%)
Query: 546 KEEQHQLAVTAYLKNSRKEHQRILAR--RQTIEERKERLESLNIQREKE----ELEQREA 599
KE+ +L L S K ++ + ++ +E K L +Q E + EL+ A
Sbjct: 208 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSA 267
Query: 600 ELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKT--VRERLEQIKKTELGAKAFKDID 657
+LQ + EE L ++++E++ ++ E+I+++ ++E+ E+I++ E + +++
Sbjct: 268 KLQA--QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 658 IEDLEELDPDFIMAKQVEQL-EKEKK--ELQERLKNQEKKIDYFERAKRLEEIPLIKSAY 714
E E+ M +Q E + EKE+K EL+E++ QEK + E+ + E+I
Sbjct: 326 WEKEEK------MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI----REQ 375
Query: 715 EEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEE 774
E+++ ++ +W Q+E+ R E+E+ + + M + E++ EE
Sbjct: 376 EKRQEQEAKMWRQEEKIR------EQEEKIREQEEMMQEQEEK-----------MGEQEE 418
Query: 775 KLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834
K+ + EE + E+ + ++ R++E++I +E+EE+ R +E+M++E+EE+ +
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKI-----REQEEKIREQEEMMQEQEEKMGEQE 473
Query: 835 AKREEELREYQERVKKLEEVERKKRQRELEIEERERR-REEERRLGDSSLSRKDSRWGDR 893
K E+ + QE+ +K+ E K R++E +I E+E + RE+E + + +++ W
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE----QEEKMWEQE 529
Query: 894 DSEGTWRKGPEADSEWRRGPPEKEWRRGEG--RDEDRSHRRDEER 936
+ + E + E++ RR E R+++ R+ EE+
Sbjct: 530 EK--------MCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 97.8 bits (242), Expect = 6e-20
Identities = 97/433 (22%), Positives = 215/433 (49%), Gaps = 58/433 (13%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREK 621
+ HQ A R+ +E + + + L Q+ + ++ ++ V++ E E ++ +
Sbjct: 100 KASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQ-HAVKQLEGEARDLISRLHDS 158
Query: 622 ERILQEHEQI------KKKTVRERLEQIKKTE--LGAKAFKDIDIEDLEELDPDFIMAKQ 673
+ E EQ +KK +E++ K L + +++ I D E + + + ++
Sbjct: 159 WKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT-ITDEELKEKNAKLQEK 217
Query: 674 VEQLEKEKKELQERLKNQEKKIDYFERAKRL--------------EEIPLIKSAYEEQRI 719
++ +E EK E+Q +K ++K+ ERAK L +E+ + + + Q +
Sbjct: 218 LQLVESEKSEIQLNVKELKRKL---ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ-V 273
Query: 720 KDMDLWE---QQEEERITTMQ---LEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYE 773
++ +LW QQ+EE++ + ERE+ ++ + R E++ MR + E
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEK----MRRQEEMMWEKE 329
Query: 774 EKLKQFEERL--AEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERER 831
EK+++ EE + EE+ LEE+ ++++ R E+E++R EE+ ++E+E+R+
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIR---------EQEEKRQEEEKIREQEKRQE 380
Query: 832 AERA--KREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSR 889
E ++EE++RE +E++++ EE+ +++ ++ E EE+ +EEE + + + R++ +
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Query: 890 WGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGR----DEDRSHRRDEERPRRLGDD-E 944
R+ E R+ E E E+E + GE +++ + EE+ RR +
Sbjct: 441 --IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498
Query: 945 DREPSLRPDDDRV 957
++E +R ++++
Sbjct: 499 EQEKKIREQEEKI 511
Score = 69.7 bits (169), Expect = 2e-11
Identities = 71/273 (26%), Positives = 136/273 (49%), Gaps = 37/273 (13%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHI---LQEKEEQHQLAVTAYLKNSRKEHQRILARRQ 573
E++R Q M K E+ + H ++E+EE+ Q + R+E + + R++
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 574 T-IEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIK 632
I E++E++ +++E + E E +K+ + EEE QE K R +E ++E E
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQE-EKMWEQEEEMQEQEEKMRRQEEKIREQE--- 445
Query: 633 KKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQE 692
K +RE+ E+I++ E ++ E E++ K EQ E + +E +E+++ QE
Sbjct: 446 -KKIREQEEKIREQE-------EMMQEQEEKMGEQ--EGKMCEQ-EAKMQEQEEKMRRQE 494
Query: 693 KKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSR 752
+KI E+ K++ E +E++I++ + Q++EE+ M + EK E + +M
Sbjct: 495 EKIR--EQEKKIRE--------QEEKIREQEEMMQEQEEK---MWEQEEKMCEQEEKMQE 541
Query: 753 MLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE 785
E MR + + E +L+Q EE++ E
Sbjct: 542 QEEK-----MRRQEEKMREQEVRLRQQEEKMQE 569
Score = 67.4 bits (163), Expect = 9e-11
Identities = 74/363 (20%), Positives = 174/363 (47%), Gaps = 44/363 (12%)
Query: 620 EKERILQEHEQIKKKTVRERLEQIK-----KTELG-AKAFKDIDIEDLEELDPDFIMA-- 671
++++ +H++ ++ + +++ I+ KTEL A + ++ LE D I
Sbjct: 97 DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 156
Query: 672 ---KQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQ 728
K +LE+ + + K ++ I+ + + + L ++ ++ +K+ + +
Sbjct: 157 DSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNA---K 213
Query: 729 EEERITTMQLEREKALEHKNRMSRMLEDRDLFV--MRLKAARQSVYEEKLKQFEERLAEE 786
+E++ ++ E+ + + + R LE L + +L+A + +E + A+
Sbjct: 214 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 273
Query: 787 RHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846
N L R Q++EE+ +R++E+ ++R E+ ++E+EE+ R ++EE++R +E
Sbjct: 274 EENELWNRLNQQQEEKM---WRQEEKIQER---EEKIQEQEEKIR----EQEEKMRRQEE 323
Query: 847 RVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEAD 906
+ E+ E+ +RQ E+ E+ E+ RE E ++ + R+ R E R +
Sbjct: 324 MM--WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE--KRQEEEKIR-----E 374
Query: 907 SEWRRGPPEKEWRRGEG-RDEDRSHRRDE----ERPRRLGDDEDR----EPSLRPDDDRV 957
E R+ K WR+ E R+++ R E E+ ++G+ E++ E ++ ++++
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 958 PRR 960
R+
Sbjct: 435 RRQ 437
Score = 50.4 bits (119), Expect = 1e-05
Identities = 31/184 (16%), Positives = 86/184 (46%), Gaps = 14/184 (7%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDRED 1237
WR++EK +E RE + E+ E RE+E Q+ +K+ + R E ++E+
Sbjct: 291 WRQEEKIQE------REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 344
Query: 1238 RFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRG 1297
+ R + + E+ + + +++ R+ +R+ + + R+ +R+ ++
Sbjct: 345 KIRELEE----KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK-- 398
Query: 1298 PPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
+R + E + +++++ E++ + + R E+ R++E++ +++ R
Sbjct: 399 --IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456
Query: 1358 AEKD 1361
+++
Sbjct: 457 EQEE 460
Score = 46.6 bits (109), Expect = 2e-04
Identities = 36/198 (18%), Positives = 94/198 (47%), Gaps = 23/198 (11%)
Query: 1178 WREKEKAREES-WGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDRE 1236
W + +EE W R+ +ERE EK ++++ + RE+ +K R E ++E
Sbjct: 279 WNRLNQQQEEKMW---RQEEKIQERE---EKIQEQEEKIREQEEK---MRRQEEMMWEKE 329
Query: 1237 DRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRR 1296
++ RR ++E W + + + R+++++R+E + R+ +R++ R+
Sbjct: 330 EKMRR-QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388
Query: 1297 GPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASW 1356
+R + E++ +++++ E++ ++ +++ E + ++EK
Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQE------------EKMWEQEEEMQEQEEKMRR 436
Query: 1357 RAEKDRESLRRTKNETDE 1374
+ EK RE ++ + + ++
Sbjct: 437 QEEKIREQEKKIREQEEK 454
Score = 45.4 bits (106), Expect = 4e-04
Identities = 42/200 (21%), Positives = 90/200 (45%), Gaps = 15/200 (7%)
Query: 1180 EKEKAREESWGPPRESRPSEE--REWDREKERDRDNQDREENDKDPERE-RDRERDVDRE 1236
E+EK RE+ E R EE RE ++ +E++ +EE ++ E + R++E + +
Sbjct: 355 EQEKIREQE-----EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 1237 DRFRRPRDEGGWRRGPAEESSSWRDSSRR-DDRDRDDRRRERDDRRDLRERRDLRDDRDR 1295
+ ++E W + EE + RR +++ R+ ++ R+ +RE+ ++ +++
Sbjct: 410 EEKMGEQEEKMWEQ--EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467
Query: 1296 RGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRER-EGEKEKA 1354
+ + E + + + K R EE+ R + E+ R++E E+E+
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEK---IREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 1355 SWRAEKDRESLRRTKNETDE 1374
W E+ E +E
Sbjct: 525 MWEQEEKMCEQEEKMQEQEE 544
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/184 (17%), Positives = 91/184 (49%), Gaps = 23/184 (12%)
Query: 1178 WREKEKARE--------ESWGPPRESRPSEERE--WDREKE-RDRDNQDREENDKDPERE 1226
WR++EK RE E +E + E+ E W++E+E ++++ + R + +K E+E
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE 445
Query: 1227 ---RDRERDV-DREDRFRRPRDEGGWRRGP-AEESSSWRDSS----RRDDRDRDDRRRER 1277
R++E + ++E+ + ++ G + G E+ + ++ R++++ R+ ++ R
Sbjct: 446 KKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIR 505
Query: 1278 DDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSR 1337
+ +RE+ ++ +++ + + + E++ +++++ ++ R L +
Sbjct: 506 EQEEKIREQEEMMQEQEEK---MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQ 562
Query: 1338 DRER 1341
E+
Sbjct: 563 QEEK 566
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/114 (24%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIE 576
E ++ Q M K E +EK + + + K R++ ++I + + ++
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519
Query: 577 ERKERLESLNIQREK--EELEQREAELQKVRKAEEERLRQEAKEREKERILQEH 628
E++E++ Q EK E+ E+ + + +K+R+ EE+ QE + R++E +QEH
Sbjct: 520 EQEEKMWE---QEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 112 bits (279), Expect = 3e-24
Identities = 99/373 (26%), Positives = 184/373 (49%), Gaps = 64/373 (17%)
Query: 512 QSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVT------AYLKNSRKEH 565
Q + E+++ + S A +V++P +++Q+ +T + +K+ K +
Sbjct: 464 QHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRN 523
Query: 566 Q--RILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKER 623
R+ + +E+ ++RLE+L + E E+L +++ E K R+ EE +L++E + R +
Sbjct: 524 TPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---K 580
Query: 624 ILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKE 683
+LQ E++ E++++ KK ++ K F ID EK +K
Sbjct: 581 VLQARERV------EQMKEEKKKQIEQK-FAQID--------------------EKTEKA 613
Query: 684 LQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKA 743
+ERL E+K AK++EE+ + EE R W QQEEE +L ++K
Sbjct: 614 KEERLA--EEKAKKKAAAKKMEEVEARRKQEEEARRLR---WLQQEEEERRHQELLQKKK 668
Query: 744 LEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERR 803
E + R+ + E + L +Q E+ E+ E R+++R+E+ R
Sbjct: 669 EEEQERLRKAAEAKRL----------------AEQREQERREQERREQERREQERREQER 712
Query: 804 ITYYREKEEEEQRRAEEQMLKERE--ERERAERAKREEELREYQERVKKLEEVERKKRQR 861
R+ E+E+RR +E++ ERE ERE+A R ++E+ RE +E+ KK E+ +RQ
Sbjct: 713 REQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQL 772
Query: 862 ELEIEERERRREE 874
+ EE+E++ +E
Sbjct: 773 Q---EEQEKKAKE 782
Score = 80.9 bits (198), Expect = 8e-15
Identities = 81/316 (25%), Positives = 153/316 (48%), Gaps = 77/316 (24%)
Query: 672 KQVEQLEK-EKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEE 730
K+ ++LE +KE E+L+ Q+ + D + +RLEE+ L + E+R++ + Q
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVEED---KRRRLEEVKLKR----EERLRKV----LQAR 585
Query: 731 ERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNR 790
ER+ M+ E++K +E K +++ E + KA + + EEK K+ + A ++
Sbjct: 586 ERVEQMKEEKKKQIEQK--FAQIDEKTE------KAKEERLAEEKAKK---KAAAKKMEE 634
Query: 791 LEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKK 850
+E R++Q +E RR+ + ++ EEE+RR +E + K++EE QER++K
Sbjct: 635 VEARRKQEEEARRLRWLQQ--EEEERRHQELLQKKKEEE---------------QERLRK 677
Query: 851 LEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWR 910
E +R QRE E E+ERR +E R + E R
Sbjct: 678 AAEAKRLAEQREQERREQERREQERR-----------------------------EQERR 708
Query: 911 RGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRR 970
E+E R E + ++ RR++ER + + ++RE +LR +++ R + ++
Sbjct: 709 ----EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR----ELEEKKK 760
Query: 971 GPEEDRFSRRGADDDR 986
E+ R + R +++
Sbjct: 761 KEEQQRLAERQLQEEQ 776
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/187 (20%), Positives = 79/187 (42%), Gaps = 21/187 (11%)
Query: 1182 EKAREESWGPPRESRPSEEREWD----REKERDRDNQDREENDKDPERERDRERDVDRED 1237
EKA+EE + + + ++ + R K+ + + R ++ ER +E+
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 670
Query: 1238 RFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRG 1297
R R +R + R+ RR+ R+ RRE++ R +ER+ +R R
Sbjct: 671 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE--QERQLAEQERRREQ 728
Query: 1298 PPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
L++ERE ++ER+ R+ L R+ E + +E + + +
Sbjct: 729 ERLQAERE---------------LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773
Query: 1358 AEKDRES 1364
E+++++
Sbjct: 774 EEQEKKA 780
Score = 45.1 bits (105), Expect = 5e-04
Identities = 37/135 (27%), Positives = 70/135 (51%), Gaps = 23/135 (17%)
Query: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELE------ 595
+LQ+K+E+ Q + + R QR RR+ +ER E ++E+ E E
Sbjct: 663 LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQ 722
Query: 596 ---------QREAELQKVRKA---EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQI 643
Q E ELQ+ KA ++E+L++E +E++K+ +E +++ ++ ++E EQ
Sbjct: 723 ERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQE--EQE 777
Query: 644 KKTELGAKAFKDIDI 658
KK + A A K +++
Sbjct: 778 KKAKEAAGASKALNV 792
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/201 (22%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 824 KEREERERAERAKREEELREY---QERVKKLEEVERKKRQR---ELEIEER-ERRREEER 876
KER+ E R + E+LR +++ ++LEEV+ K+ +R L+ ER E+ +EE++
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 596
Query: 877 RLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEER 936
+ + ++ D K +A E K+ + +E + R+ EE
Sbjct: 597 KQIEQKFAQID------------EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 644
Query: 937 PRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDR 996
RRL + E R + + ++ ++ R+ E R + + + R R + R
Sbjct: 645 ARRLRWLQQEEEE-RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERR 703
Query: 997 PPRRIADEDRGNWRH-ADDDR 1016
R E R R A+ +R
Sbjct: 704 EQERREQERREQERQLAEQER 724
Score = 40.8 bits (94), Expect = 0.009
Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 12/197 (6%)
Query: 1180 EKEKAREESWGPPRESRPSEEREWDREKER--DRDNQDREENDKDPERERDR------ER 1231
EKE+ R E+ E+ ++ + +K R + REE + + R+R E+
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK 595
Query: 1232 DVDREDRFRR--PRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDL 1289
E +F + + E AEE + + ++++ + + + RR++ ++ R LR +
Sbjct: 596 KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME-EVEARRKQEEEARRLRWLQQE 654
Query: 1290 RDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREG 1349
++R + + + EE R+A + K E+R+ RR RE++R +
Sbjct: 655 EEERRHQELLQKKKEEEQERLRKAAEAK-RLAEQREQERREQERREQERREQERREQERR 713
Query: 1350 EKEKASWRAEKDRESLR 1366
E+E+ E+ RE R
Sbjct: 714 EQERQLAEQERRREQER 730
Score = 37.4 bits (85), Expect = 0.10
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 29/198 (14%)
Query: 1199 EEREWDREKERDRDNQDREENDKDPER---ERDRERDVDREDRFRRPR----------DE 1245
EER + R+R Q +EE K E+ + D + + +E+R + +E
Sbjct: 575 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 634
Query: 1246 GGWRRGPAEESSSWR-----DSSRRDDRDRDDRRRERDDR-RDLRERRDLRDDRDRRGPP 1299
RR EE+ R + RR ++ E +R R E + L + R++
Sbjct: 635 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE--- 691
Query: 1300 LRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAE 1359
R E+E RR +R++ E R+ R++ R++ER ERE ++ + + R +
Sbjct: 692 -RREQERREQERREQERREQ--ERREQERQLAEQERRREQER-LQAERELQEREKALRLQ 747
Query: 1360 KD---RESLRRTKNETDE 1374
K+ RE + K E +
Sbjct: 748 KEQLQRELEEKKKKEEQQ 765
Score = 37.0 bits (84), Expect = 0.13
Identities = 24/139 (17%), Positives = 60/139 (43%), Gaps = 11/139 (7%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDN-----------QDREENDKDPERER 1227
+++E+AR W E + ++KE +++ + RE+ ++ ER
Sbjct: 640 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 699
Query: 1228 DRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERR 1287
R+ +R ++ RR ++ + E + +R++ R ++ +R+L E++
Sbjct: 700 QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 759
Query: 1288 DLRDDRDRRGPPLRSEREE 1306
+ + L+ E+E+
Sbjct: 760 KKEEQQRLAERQLQEEQEK 778
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 111 bits (278), Expect = 4e-24
Identities = 99/371 (26%), Positives = 182/371 (49%), Gaps = 64/371 (17%)
Query: 512 QSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVT------AYLKNSRKEH 565
Q + E+++ + S A +V++P +++Q+ +T + +K+ K +
Sbjct: 464 QHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRN 523
Query: 566 QRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERIL 625
+ R E+ ++RLE+L + E E+L +++ E K R+ EE +L++E + R ++L
Sbjct: 524 TPL--RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLR---KVL 578
Query: 626 QEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQ 685
Q E++ E++++ KK ++ K F ID EK +K +
Sbjct: 579 QARERV------EQMKEEKKKQIEQK-FAQID--------------------EKTEKAKE 611
Query: 686 ERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALE 745
ERL E+K AK++EE+ + EE R W QQEEE +L ++K E
Sbjct: 612 ERLA--EEKAKKKAAAKKMEEVEARRKQEEEARRLR---WLQQEEEERRHQELLQKKKEE 666
Query: 746 HKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRIT 805
+ R+ + E + L +Q E+ E+ E R+++R+E+ R
Sbjct: 667 EQERLRKAAEAKRL----------------AEQREQERREQERREQERREQERREQERRE 710
Query: 806 YYREKEEEEQRRAEEQMLKERE--ERERAERAKREEELREYQERVKKLEEVERKKRQREL 863
R+ E+E+RR +E++ ERE ERE+A R ++E+ RE +E+ KK E+ +RQ +
Sbjct: 711 QERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ- 769
Query: 864 EIEERERRREE 874
EE+E++ +E
Sbjct: 770 --EEQEKKAKE 778
Score = 81.3 bits (199), Expect = 6e-15
Identities = 72/289 (24%), Positives = 138/289 (47%), Gaps = 51/289 (17%)
Query: 708 PLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKA-------LEHKNRMSRMLEDRDLF 760
PL E++R + +L ++E E++ ++E +K L+ + R+ ++L+ R+
Sbjct: 525 PLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER- 583
Query: 761 VMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRK---EERRITYYREKEEEEQRR 817
V ++K ++ E+K Q +E+ + + RL E K ++K ++ R K+EEE RR
Sbjct: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643
Query: 818 AEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877
+ +E EER E ++++E E QER++K E +R QRE E E+ERR +E R
Sbjct: 644 LR-WLQQEEEERRHQELLQKKKE--EEQERLRKAAEAKRLAEQREQERREQERREQERR- 699
Query: 878 LGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERP 937
+ E R E+E R E + ++ RR++ER
Sbjct: 700 ----------------------------EQERR----EQERREQERQLAEQERRREQERL 727
Query: 938 RRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDR 986
+ + ++RE +LR +++ R + ++ E+ R + R +++
Sbjct: 728 QAERELQEREKALRLQKEQLQR----ELEEKKKKEEQQRLAERQLQEEQ 772
Score = 46.6 bits (109), Expect = 2e-04
Identities = 38/187 (20%), Positives = 79/187 (42%), Gaps = 21/187 (11%)
Query: 1182 EKAREESWGPPRESRPSEEREWD----REKERDRDNQDREENDKDPERERDRERDVDRED 1237
EKA+EE + + + ++ + R K+ + + R ++ ER +E+
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 666
Query: 1238 RFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRG 1297
R R +R + R+ RR+ R+ RRE++ R +ER+ +R R
Sbjct: 667 EQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE--QERQLAEQERRREQ 724
Query: 1298 PPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
L++ERE ++ER+ R+ L R+ E + +E + + +
Sbjct: 725 ERLQAERE---------------LQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769
Query: 1358 AEKDRES 1364
E+++++
Sbjct: 770 EEQEKKA 776
Score = 45.1 bits (105), Expect = 5e-04
Identities = 37/135 (27%), Positives = 70/135 (51%), Gaps = 23/135 (17%)
Query: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELE------ 595
+LQ+K+E+ Q + + R QR RR+ +ER E ++E+ E E
Sbjct: 659 LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQ 718
Query: 596 ---------QREAELQKVRKA---EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQI 643
Q E ELQ+ KA ++E+L++E +E++K+ +E +++ ++ ++E EQ
Sbjct: 719 ERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKK---EEQQRLAERQLQE--EQE 773
Query: 644 KKTELGAKAFKDIDI 658
KK + A A K +++
Sbjct: 774 KKAKEAAGASKALNV 788
Score = 41.6 bits (96), Expect = 0.005
Identities = 44/198 (22%), Positives = 89/198 (44%), Gaps = 12/198 (6%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKER--DRDNQDREENDKDPERERDR------E 1230
+EKE+ R E+ E+ ++ + +K R + REE + + R+R E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 1231 RDVDREDRFRR--PRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRD 1288
+ E +F + + E AEE + + ++++ + + + RR++ ++ R LR +
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME-EVEARRKQEEEARRLRWLQQ 649
Query: 1289 LRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDRERE 1348
++R + + + EE R+A + K E+R+ RR RE++R +
Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEAK-RLAEQREQERREQERREQERREQERREQER 708
Query: 1349 GEKEKASWRAEKDRESLR 1366
E+E+ E+ RE R
Sbjct: 709 REQERQLAEQERRREQER 726
Score = 37.4 bits (85), Expect = 0.10
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 29/198 (14%)
Query: 1199 EEREWDREKERDRDNQDREENDKDPER---ERDRERDVDREDRFRRPR----------DE 1245
EER + R+R Q +EE K E+ + D + + +E+R + +E
Sbjct: 571 EERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
Query: 1246 GGWRRGPAEESSSWR-----DSSRRDDRDRDDRRRERDDR-RDLRERRDLRDDRDRRGPP 1299
RR EE+ R + RR ++ E +R R E + L + R++
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQE--- 687
Query: 1300 LRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAE 1359
R E+E RR +R++ E R+ R++ R++ER ERE ++ + + R +
Sbjct: 688 -RREQERREQERREQERREQ--ERREQERQLAEQERRREQER-LQAERELQEREKALRLQ 743
Query: 1360 KD---RESLRRTKNETDE 1374
K+ RE + K E +
Sbjct: 744 KEQLQRELEEKKKKEEQQ 761
Score = 37.0 bits (84), Expect = 0.13
Identities = 24/139 (17%), Positives = 60/139 (43%), Gaps = 11/139 (7%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDN-----------QDREENDKDPERER 1227
+++E+AR W E + ++KE +++ + RE+ ++ ER
Sbjct: 636 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 695
Query: 1228 DRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERR 1287
R+ +R ++ RR ++ + E + +R++ R ++ +R+L E++
Sbjct: 696 QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 755
Query: 1288 DLRDDRDRRGPPLRSEREE 1306
+ + L+ E+E+
Sbjct: 756 KKEEQQRLAERQLQEEQEK 774
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 99.8 bits (247), Expect = 2e-20
Identities = 84/368 (22%), Positives = 188/368 (51%), Gaps = 50/368 (13%)
Query: 592 EELEQREAELQ-KVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA 650
EEL+++ AELQ K+R E E+ + ++ +R L+ + + + ++ Q++ LG
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL----LPQQQLQVEADRLG- 268
Query: 651 KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLI 710
K + + + +++ + + +Q E++ +E+++ QE+K+
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM--------------- 313
Query: 711 KSAYEEQRIKDMD--LWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAAR 768
+E +I++ + +W Q+E+ M + EK E +++M R E K
Sbjct: 314 --CEQELKIREQEEKMWRQEEK-----MHEQEEKIREQEDKMWRQEE---------KIRE 357
Query: 769 QSVYEEKLKQFEERL-AEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE 827
Q EEK+++ EE++ +E R ++ K Q +EE + E+E++R E+ +E++
Sbjct: 358 Q---EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 828 ERERAERAK-REEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRK 886
RE+ E+ + +EEE+ +E++++LEE+ + + ++ E+EE+ + EE+ + + + R+
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 887 DSRWGDRDSEGTWRKG---PEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDD 943
+ + +++ E TWR+ + + W + EK WR+ E E +++E + ++
Sbjct: 475 EEKIQEQE-EKTWRQEKLLKQEEKIWEQ--EEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Query: 944 EDREPSLR 951
+ RE +R
Sbjct: 532 KMREQEVR 539
Score = 97.8 bits (242), Expect = 6e-20
Identities = 89/370 (24%), Positives = 189/370 (51%), Gaps = 83/370 (22%)
Query: 520 RNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERK 579
+ QL + L K L+ + LQ + E+++L L N ++E +++ + + I+E++
Sbjct: 257 QQQLQVEADRLGKELQSVSAK--LQAQVEENELW---NLLNQQQE-EKMWRQEEKIQEQE 310
Query: 580 ERL--ESLNIQREKEELEQREAEL----QKVRKAEEERLRQEAKEREKERILQEHEQI-- 631
E++ + L I+ ++E++ ++E ++ +K+R+ E++ RQE K RE+E ++E E+
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 632 -KKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKN 690
+++ +RE+ E+I++ E EE M +Q E++ +++++ QE++
Sbjct: 371 RQEEKIREQDEKIQEQE--------------EE------MWRQEEKIREQEEKRQEKMWR 410
Query: 691 QEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRM 750
QEKK+ + E+ R ++ ++W Q+E+ R +
Sbjct: 411 QEKKM---------------REQDEKIREQEEEMWRQEEKIR----------------EL 439
Query: 751 SRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLE-ERKRQRKEERRITYYRE 809
M++D+ EEKL++ EE++ EE E E K QR+EE+ +
Sbjct: 440 EEMMQDQ---------------EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 810 KEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEI-EER 868
+E+ +E+ + E+EE+ + K E+ + QE+ +K++ E K R++E+ + ++
Sbjct: 485 TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 869 ERRREEERRL 878
E+ +E+E RL
Sbjct: 545 EKMQEQEVRL 554
Score = 79.7 bits (195), Expect = 2e-14
Identities = 112/516 (21%), Positives = 227/516 (43%), Gaps = 65/516 (12%)
Query: 521 NQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEER-- 578
N+L S V K + I EK Q + AYL+N ++ + +EE
Sbjct: 37 NKLEQQSKVRNKGHGKPREKSIADEKFFQLS-EMEAYLENRKRRGTKRWDEDDDLEESED 95
Query: 579 ----KERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKK 634
KE L+ + +E + +A + V+K +E K +EK + E +K
Sbjct: 96 SKQCKESLKRVTFTLPDDEAIE-DAGVSHVKKNSDEVKSSFKKRQEK---MNEKNYTFRK 151
Query: 635 TVRERLEQIKKTELGA-KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK----ELQERLK 689
V + ++ E+ A K ++ +E+ D M +E+L KE+ EL
Sbjct: 152 RVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTI 211
Query: 690 NQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITT----MQLEREKALE 745
E+ + + A+ E++ L++S E ++ DL + E ++ +Q+E ++ +
Sbjct: 212 TDEELKE--KNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGK 269
Query: 746 HKNRMSRML----EDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEE 801
+S L E+ +L+ + EEK+ + EE++ E+ E+ + R++E
Sbjct: 270 ELQSVSAKLQAQVEENELWNLL-----NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 802 RRITYYREK--EEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKR 859
++ EK E+EE+ R +E + +EE+ R ++EE++RE +E++ + EE R++
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIR----EQEEKIREQEEKMWRQEEKIREQD 380
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
++ E EE R+EE+ R + R++ W +K E D + R E+ WR
Sbjct: 381 EKIQEQEEEMWRQEEKIR--EQEEKRQEKMWRQE------KKMREQDEKIRE-QEEEMWR 431
Query: 920 RGEGRDEDRSHRRDEERPRRLGDD--EDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRF 977
+ E E +D+E R ++ ++ E ++ ++++ R +E++
Sbjct: 432 QEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR-------------QEEKI 478
Query: 978 SRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHAD 1013
+ + +WR + +I +++ WR +
Sbjct: 479 Q----EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Score = 55.5 bits (132), Expect = 4e-07
Identities = 37/201 (18%), Positives = 87/201 (43%), Gaps = 8/201 (3%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREW-DREKERDRDNQDREENDK---DPERERDRERDV 1233
WR++EK E+ + R E++ W EK R+++ + RE+ +K E+ R+++ +
Sbjct: 328 WRQEEKMHEQE----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 1234 DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
++ ++E + + WR + ++D R +E + R + R+L +
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443
Query: 1294 DRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEK 1353
+ LR E++ ++++++ ++ + R + + E+ E+E+
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Query: 1354 ASWRAEKDRESLRRTKNETDE 1374
WR E+ E +E
Sbjct: 504 KMWRQEEKMWEQEEKMQEQEE 524
Score = 53.5 bits (127), Expect = 1e-06
Identities = 44/198 (22%), Positives = 92/198 (46%), Gaps = 22/198 (11%)
Query: 1178 WREKEKAREESWGPPRES---RPSEEREW-DREKERDRDNQDREENDK----------DP 1223
WR++EK +E+ + R EE+ W EK +++ + RE+ DK
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE 359
Query: 1224 ERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDL 1283
E+ R++E + R++ R +DE + +E WR + R+++++R+E+ R++
Sbjct: 360 EKIREQEEKMWRQEEKIREQDE----KIQEQEEEMWRQEEK--IREQEEKRQEKMWRQEK 413
Query: 1284 RERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRER-D 1342
+ R R++ R E E++ +++++ E + + + E+
Sbjct: 414 KMREQDEKIREQEEEMWRQE-EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 1343 RDREREGEKEKASWRAEK 1360
R E+ E+E+ +WR EK
Sbjct: 473 RQEEKIQEQEEKTWRQEK 490
Score = 41.6 bits (96), Expect = 0.005
Identities = 35/186 (18%), Positives = 87/186 (46%), Gaps = 36/186 (19%)
Query: 1194 ESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPA 1253
+++ E W+ ++ + R+E +K E+E E+ ++E + R
Sbjct: 279 QAQVEENELWNLLNQQQEEKMWRQE-EKIQEQE---EKMCEQELKIRE------------ 322
Query: 1254 EESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRA 1313
+E WR + +++++ RE++D+ R+ +R+ ++ +R + E++ WR+
Sbjct: 323 QEEKMWRQEEKM--HEQEEKIREQEDKM-WRQEEKIREQEEK----IREQEEKM--WRQE 373
Query: 1314 DD--RKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNE 1371
+ +D++++E++ R+ ++ RE+E ++++ WR EK E
Sbjct: 374 EKIREQDEKIQEQEEEMW---------RQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 1372 TDEDGW 1377
+E+ W
Sbjct: 425 QEEEMW 430
Score = 40.0 bits (92), Expect = 0.016
Identities = 50/191 (26%), Positives = 98/191 (51%), Gaps = 25/191 (13%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIE 576
E+IR Q M K E+ + +EK + + + + +++ ++I + + I+
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 577 ERKE---RLESLNIQREK-----EELEQREAEL----QKVRKAEEERLRQE--AKEREKE 622
E++E R E L Q EK E++ ++E ++ +K+++ EE+ RQE +E+E
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE-V 538
Query: 623 RILQEHEQIKKKTVR-----ERLEQI-KKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQ 676
R+ Q+ E+++++ VR ERL ++ +K EL A ++ + L L P QVE
Sbjct: 539 RLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTP----ILQVEL 594
Query: 677 LEKEKKELQER 687
+E + LQ++
Sbjct: 595 KSQEAQSLQQQ 605
Score = 37.4 bits (85), Expect = 0.10
Identities = 31/165 (18%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 1169 WRPLVKPGGWREKEKAREES-WGPPRESRPSEEREWDREKERDRDNQDREENDKDPERER 1227
WR K EK + +EE W + R EE D+E ++ + E+ ++ E+ +
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE---EKLREVEEKMQEEEEKMQ 465
Query: 1228 DRERDVDREDRFRRPRDEGGWRRGP--AEESSSWRDSSRRDDRDRDDRRRERDDRRDLRE 1285
++E + R++ + ++E WR+ +E W + ++++ E++++ +E
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM--WRQEEKMWEQEEKMQEQE 523
Query: 1286 RRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRV 1330
+ R + R +EV W++ + ++ V ++ R+
Sbjct: 524 EKMQRQEEKMR-------EQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 99.8 bits (247), Expect = 2e-20
Identities = 84/368 (22%), Positives = 188/368 (51%), Gaps = 50/368 (13%)
Query: 592 EELEQREAELQ-KVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA 650
EEL+++ AELQ K+R E E+ + ++ +R L+ + + + ++ Q++ LG
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLL----LPQQQLQVEADRLG- 268
Query: 651 KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLI 710
K + + + +++ + + +Q E++ +E+++ QE+K+
Sbjct: 269 KELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKM--------------- 313
Query: 711 KSAYEEQRIKDMD--LWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAAR 768
+E +I++ + +W Q+E+ M + EK E +++M R E K
Sbjct: 314 --CEQELKIREQEEKMWRQEEK-----MHEQEEKIREQEDKMWRQEE---------KIRE 357
Query: 769 QSVYEEKLKQFEERL-AEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE 827
Q EEK+++ EE++ +E R ++ K Q +EE + E+E++R E+ +E++
Sbjct: 358 Q---EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKK 414
Query: 828 ERERAERAK-REEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRK 886
RE+ E+ + +EEE+ +E++++LEE+ + + ++ E+EE+ + EE+ + + + R+
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 887 DSRWGDRDSEGTWRKG---PEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDD 943
+ + +++ E TWR+ + + W + EK WR+ E E +++E + ++
Sbjct: 475 EEKIQEQE-EKTWRQEKLLKQEEKIWEQ--EEKMWRQEEKMWEQEEKMQEQEEKMQRQEE 531
Query: 944 EDREPSLR 951
+ RE +R
Sbjct: 532 KMREQEVR 539
Score = 97.8 bits (242), Expect = 6e-20
Identities = 89/370 (24%), Positives = 189/370 (51%), Gaps = 83/370 (22%)
Query: 520 RNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERK 579
+ QL + L K L+ + LQ + E+++L L N ++E +++ + + I+E++
Sbjct: 257 QQQLQVEADRLGKELQSVSAK--LQAQVEENELW---NLLNQQQE-EKMWRQEEKIQEQE 310
Query: 580 ERL--ESLNIQREKEELEQREAEL----QKVRKAEEERLRQEAKEREKERILQEHEQI-- 631
E++ + L I+ ++E++ ++E ++ +K+R+ E++ RQE K RE+E ++E E+
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370
Query: 632 -KKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKN 690
+++ +RE+ E+I++ E EE M +Q E++ +++++ QE++
Sbjct: 371 RQEEKIREQDEKIQEQE--------------EE------MWRQEEKIREQEEKRQEKMWR 410
Query: 691 QEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRM 750
QEKK+ + E+ R ++ ++W Q+E+ R +
Sbjct: 411 QEKKM---------------REQDEKIREQEEEMWRQEEKIR----------------EL 439
Query: 751 SRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLE-ERKRQRKEERRITYYRE 809
M++D+ EEKL++ EE++ EE E E K QR+EE+ +
Sbjct: 440 EEMMQDQ---------------EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 810 KEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEI-EER 868
+E+ +E+ + E+EE+ + K E+ + QE+ +K++ E K R++E+ + ++
Sbjct: 485 TWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 869 ERRREEERRL 878
E+ +E+E RL
Sbjct: 545 EKMQEQEVRL 554
Score = 91.3 bits (225), Expect = 6e-18
Identities = 98/427 (22%), Positives = 210/427 (49%), Gaps = 60/427 (14%)
Query: 550 HQLAVTAYLKNSRKEHQRILAR--RQTIEERKERLESLNIQREKEELEQREAELQKVRKA 607
H + + Y++ KE + R TI + + + ++ +Q + +E ++E+Q K
Sbjct: 184 HAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKD 243
Query: 608 EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPD 667
+ +L ER + + Q+ Q++ + + L+ + +L A+ ++ ++ +L +
Sbjct: 244 LKRKL-----ERAQLLLPQQQLQVEADRLGKELQSVS-AKLQAQV-EENELWNLLNQQQE 296
Query: 668 FIMAKQVEQL-EKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMD--L 724
M +Q E++ E+E+K ++ LK +E++ + + +++ E +E++I++ + +
Sbjct: 297 EKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHE--------QEEKIREQEDKM 348
Query: 725 WEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLA 784
W Q+E+ R + EK E + +M R E +R + + EE++ + EE++
Sbjct: 349 WRQEEKIRE-----QEEKIREQEEKMWRQEEK-----IREQDEKIQEQEEEMWRQEEKIR 398
Query: 785 EERHNRLEERKRQRKEER-RITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELRE 843
E+ R E+ RQ K+ R + RE+EEE R +E+ ++E EE + + K E +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWR--QEEKIRELEEMMQDQEEKLREVEEK 456
Query: 844 YQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGP 903
QE +K++E E K +++E +I+E+E + + +L L +++ W E WR+
Sbjct: 457 MQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL----LKQEEKIW--EQEEKMWRQ-- 508
Query: 904 EADSEWRRGPPEKEWRRGEG-RDEDRSHRRDEERPR----RLGDDEDR----EPSLRPDD 954
EK W + E ++++ +R EE+ R RL E++ E L+ +
Sbjct: 509 ----------EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELE 558
Query: 955 DRVPRRG 961
+R+ + G
Sbjct: 559 ERLGKLG 565
Score = 82.0 bits (201), Expect = 4e-15
Identities = 113/514 (21%), Positives = 227/514 (44%), Gaps = 61/514 (11%)
Query: 521 NQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEER-- 578
N+L S V K + I EK Q + AYL+N ++ + +EE
Sbjct: 37 NKLEQQSKVRNKGHGKPREKSIADEKFFQLS-EMEAYLENRKRRGTKRWDEDDDLEESED 95
Query: 579 ----KERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKK 634
KE L+ + +E + +A + V+K +E K +EK + E +K
Sbjct: 96 SKQCKESLKRVTFTLPDDEAIE-DAGVSHVKKNSDEVKSSFKKRQEK---MNEKNYTFRK 151
Query: 635 TVRERLEQIKKTELGA-KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQ-ERLKNQE 692
V + ++ E+ A K ++ +E+ D M +E+L KE+ L E +N
Sbjct: 152 RVVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTI 211
Query: 693 KKIDYFERAKRLEE-IPLIKSAYEEQRIKDMDLWEQQEEERITT----MQLEREKALEHK 747
+ E+ L+E + L++S E ++ DL + E ++ +Q+E ++ +
Sbjct: 212 TDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKEL 271
Query: 748 NRMSRML----EDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERR 803
+S L E+ +L+ + EEK+ + EE++ E+ E+ + R++E +
Sbjct: 272 QSVSAKLQAQVEENELWNLL-----NQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 804 ITYYREK--EEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQR 861
+ EK E+EE+ R +E + +EE+ R ++EE++RE +E++ + EE R++ ++
Sbjct: 327 MWRQEEKMHEQEEKIREQEDKMWRQEEKIR----EQEEKIREQEEKMWRQEEKIREQDEK 382
Query: 862 ELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRG 921
E EE R+EE+ R + R++ W +K E D + R E+ WR+
Sbjct: 383 IQEQEEEMWRQEEKIR--EQEEKRQEKMWRQE------KKMREQDEKIRE-QEEEMWRQE 433
Query: 922 EGRDEDRSHRRDEERPRRLGDD--EDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSR 979
E E +D+E R ++ ++ E ++ ++++ R +E++
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQR-------------QEEKIQ- 479
Query: 980 RGADDDRPSWRNTDDDRPPRRIADEDRGNWRHAD 1013
+ + +WR + +I +++ WR +
Sbjct: 480 ---EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEE 510
Score = 55.5 bits (132), Expect = 4e-07
Identities = 37/201 (18%), Positives = 87/201 (43%), Gaps = 8/201 (3%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREW-DREKERDRDNQDREENDK---DPERERDRERDV 1233
WR++EK E+ + R E++ W EK R+++ + RE+ +K E+ R+++ +
Sbjct: 328 WRQEEKMHEQE----EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKI 383
Query: 1234 DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
++ ++E + + WR + ++D R +E + R + R+L +
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443
Query: 1294 DRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEK 1353
+ LR E++ ++++++ ++ + R + + E+ E+E+
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE 503
Query: 1354 ASWRAEKDRESLRRTKNETDE 1374
WR E+ E +E
Sbjct: 504 KMWRQEEKMWEQEEKMQEQEE 524
Score = 53.5 bits (127), Expect = 1e-06
Identities = 44/198 (22%), Positives = 92/198 (46%), Gaps = 22/198 (11%)
Query: 1178 WREKEKAREESWGPPRES---RPSEEREW-DREKERDRDNQDREENDK----------DP 1223
WR++EK +E+ + R EE+ W EK +++ + RE+ DK
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE 359
Query: 1224 ERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDL 1283
E+ R++E + R++ R +DE + +E WR + R+++++R+E+ R++
Sbjct: 360 EKIREQEEKMWRQEEKIREQDE----KIQEQEEEMWRQEEK--IREQEEKRQEKMWRQEK 413
Query: 1284 RERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRER-D 1342
+ R R++ R E E++ +++++ E + + + E+
Sbjct: 414 KMREQDEKIREQEEEMWRQE-EKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQ 472
Query: 1343 RDREREGEKEKASWRAEK 1360
R E+ E+E+ +WR EK
Sbjct: 473 RQEEKIQEQEEKTWRQEK 490
Score = 41.6 bits (96), Expect = 0.005
Identities = 35/186 (18%), Positives = 87/186 (46%), Gaps = 36/186 (19%)
Query: 1194 ESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPA 1253
+++ E W+ ++ + R+E +K E+E E+ ++E + R
Sbjct: 279 QAQVEENELWNLLNQQQEEKMWRQE-EKIQEQE---EKMCEQELKIRE------------ 322
Query: 1254 EESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRA 1313
+E WR + +++++ RE++D+ R+ +R+ ++ +R + E++ WR+
Sbjct: 323 QEEKMWRQEEKM--HEQEEKIREQEDKM-WRQEEKIREQEEK----IREQEEKM--WRQE 373
Query: 1314 DD--RKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNE 1371
+ +D++++E++ R+ ++ RE+E ++++ WR EK E
Sbjct: 374 EKIREQDEKIQEQEEEMW---------RQEEKIREQEEKRQEKMWRQEKKMREQDEKIRE 424
Query: 1372 TDEDGW 1377
+E+ W
Sbjct: 425 QEEEMW 430
Score = 40.0 bits (92), Expect = 0.016
Identities = 50/191 (26%), Positives = 98/191 (51%), Gaps = 25/191 (13%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIE 576
E+IR Q M K E+ + +EK + + + + +++ ++I + + I+
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQ 479
Query: 577 ERKE---RLESLNIQREK-----EELEQREAEL----QKVRKAEEERLRQE--AKEREKE 622
E++E R E L Q EK E++ ++E ++ +K+++ EE+ RQE +E+E
Sbjct: 480 EQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQE-V 538
Query: 623 RILQEHEQIKKKTVR-----ERLEQI-KKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQ 676
R+ Q+ E+++++ VR ERL ++ +K EL A ++ + L L P QVE
Sbjct: 539 RLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTP----ILQVEL 594
Query: 677 LEKEKKELQER 687
+E + LQ++
Sbjct: 595 KSQEAQSLQQQ 605
Score = 37.4 bits (85), Expect = 0.10
Identities = 31/165 (18%), Positives = 74/165 (44%), Gaps = 15/165 (9%)
Query: 1169 WRPLVKPGGWREKEKAREES-WGPPRESRPSEEREWDREKERDRDNQDREENDKDPERER 1227
WR K EK + +EE W + R EE D+E ++ + E+ ++ E+ +
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQE---EKLREVEEKMQEEEEKMQ 465
Query: 1228 DRERDVDREDRFRRPRDEGGWRRGP--AEESSSWRDSSRRDDRDRDDRRRERDDRRDLRE 1285
++E + R++ + ++E WR+ +E W + ++++ E++++ +E
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM--WRQEEKMWEQEEKMQEQE 523
Query: 1286 RRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRV 1330
+ R + R +EV W++ + ++ V ++ R+
Sbjct: 524 EKMQRQEEKMR-------EQEVRLWQQEEKMQEQEVRLQELEERL 561
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 99.8 bits (247), Expect = 2e-20
Identities = 122/583 (20%), Positives = 220/583 (37%), Gaps = 90/583 (15%)
Query: 583 ESLNIQREKEELEQREA---ELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRER 639
E + I EKE E + E Q+V +A EE ++ +EK IL + K + +
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEV-EANEENVKVHGGRKEKTEILSDDLTDKAEVSEGK 640
Query: 640 LEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFE 699
+ + + E G + D E+ + E + E++E E+ K + + E
Sbjct: 641 AKSVGEAEDGPEGRGDGTCEE---------GSSGAEHWQDEEREKGEKDKGRGE----ME 687
Query: 700 RAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDL 759
R E K E++ K D EQ+++ER Q ER + +E
Sbjct: 688 RPGEGE-----KELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG----------- 731
Query: 760 FVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAE 819
EE H EE + R+EE EKE E + E
Sbjct: 732 -------------------------EEEHGEGEEEEGDREEEE------EKEGEGKEEGE 760
Query: 820 EQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLG 879
+ ++ E+E ER K +ER K E+ E + Q E E EE E R EE+ G
Sbjct: 761 GEEVEGEREKEEGERKK--------EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGG 812
Query: 880 DSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRR 939
+ + G+R+ E +G E + E E E GEG+ E+ + E
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Query: 940 LGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPR 999
G+ E E + + +++ G G EE +++ + ++
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE---GEGEGEEEEGEGKGEEEGEEGE 929
Query: 1000 RIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGG------A 1053
+E+ G D + +E+ G W +E+ G G ++ G G
Sbjct: 930 GEGEEEEGEGEGEDGEGEG----EEEEGEWE-GEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Query: 1054 DDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRG-MDDDRGPRRGMDDDRGPRRG 1112
+ E ++ G G ++ G G +++ G G ++ + G G +++ G G
Sbjct: 985 EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG-EEEEGEEEG 1043
Query: 1113 LDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDD 1155
++R +++R R E++ G ++ ++ R+ ++
Sbjct: 1044 --EEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084
Score = 83.2 bits (204), Expect = 2e-15
Identities = 102/483 (21%), Positives = 188/483 (38%), Gaps = 74/483 (15%)
Query: 778 QFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKR 837
Q EER E+ E +R + E+ + EKEE ++R EEQ KERE+ + ER +
Sbjct: 670 QDEEREKGEKDKGRGEMERPGEGEKELA---EKEEWKKRDGEEQEQKEREQGHQKERNQE 726
Query: 838 -----EEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGD 892
EEE E +E EE E K+ + + E E E E E+ G+ + +
Sbjct: 727 MEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEK 786
Query: 893 RDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRP 952
+ EG +G E ++E R E+ G E+ R+EE G++E+ E
Sbjct: 787 GEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846
Query: 953 DDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHA 1012
+ +++ G +G EE G + + E+ G
Sbjct: 847 GEG-------EEEEGEGKGEEE------GEEGE-----------------GEEEGEEGEG 876
Query: 1013 DDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRG 1072
+ + G E+ G +E+ G G ++ G G ++E + + G G
Sbjct: 877 EGEEEEGEGEGEEEGEGE-GEEEEGEGEGEEEGEGE---GEEEEGEGKGEEEGEEGEGEG 932
Query: 1073 LDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRG 1132
+++ G G D G G +++ G G +++ G G ++ G + +
Sbjct: 933 -EEEEGEGEGED---GEGEG-EEEEGEWEG-EEEEGEGEGEEEGEGEGEEGEGE------ 980
Query: 1133 AEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPP 1192
E++ G +++ ++ G+ G + + EE G
Sbjct: 981 GEEEEGEGEGEEEE------GEEEGEEEGEGEEEG-------------EGEGEEEEEGEV 1021
Query: 1193 RESRPSEEREWDREKER-DRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRG 1251
EE E + E+E + + ++RE+ + E R+RE + + E +++ +E R+
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081
Query: 1252 PAE 1254
E
Sbjct: 1082 GEE 1084
Score = 79.0 bits (193), Expect = 3e-14
Identities = 114/662 (17%), Positives = 240/662 (36%), Gaps = 85/662 (12%)
Query: 665 DPDFIMAKQVEQLEKEKKELQERLK------NQEKKIDYFERAKRLEEIPLIKSAYEE-- 716
+PD+++ + ++ E + E L N + K L+ P+ K ++
Sbjct: 470 EPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSNEKSLKLSPVQKQKKQQTI 529
Query: 717 -QRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEK 775
+ +D L E + + M +E + + + +F+ + ++ +E+
Sbjct: 530 GELTQDTALTENDDSDEYEEMSEMKE------GKACKQHVSQGIFMTQPATTIEAFSDEE 583
Query: 776 LKQFEERLAEE--RHNRLEERKRQRKEERRITYYREKEEEE--------QRRAEEQMLKE 825
++ EE+ E + N +EE++ + EE + KE+ E + E K
Sbjct: 584 VEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKS 643
Query: 826 REERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSR 885
E E + + E + ++ ER+K +++ E ER E E+ L +
Sbjct: 644 VGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKE--- 700
Query: 886 KDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEW---RRGEGRDEDRSHRRDEERP----- 937
W RD E +K E + R +E GEG +E+ +EE+
Sbjct: 701 ---EWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE 757
Query: 938 ----RRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTD 993
+ + ++E R ++R + ++ G + EE+ RG + +
Sbjct: 758 EGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGG 817
Query: 994 D--DRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRG 1051
+ + R +E+ G + + G E+ +E+ G ++ G
Sbjct: 818 EVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE---EG 874
Query: 1052 GADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRR 1111
+ E ++ G G +++ G G ++ G +++ G +G ++
Sbjct: 875 EGEGEEEEGEGEGEEEGEGEG-EEEEGEGEGEEEGEGEG---EEEEGEGKGEEEGEEGEG 930
Query: 1112 GLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRP 1171
+++ G D + E++ G W +++ G+ G
Sbjct: 931 EGEEEEGEGEGEDGEG----EGEEEEGEWEGEEEEG------------EGEGEEEGE--- 971
Query: 1172 LVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRER 1231
G E E EE G EE E + E E + + ++ E + + E E + E
Sbjct: 972 ----GEGEEGEGEGEEEEGEGE----GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG 1023
Query: 1232 DVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRD 1291
+V+ E+ EG EE R+ + +R +R E ++ +E + +
Sbjct: 1024 EVEGEE------GEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEEN 1077
Query: 1292 DR 1293
+R
Sbjct: 1078 ER 1079
Score = 62.0 bits (149), Expect = 4e-09
Identities = 120/678 (17%), Positives = 241/678 (35%), Gaps = 82/678 (12%)
Query: 715 EEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLF----VMRLKAARQS 770
+E + + DL + +E + + ++ +E +++ + + + E D+ +M L + +S
Sbjct: 456 QESVLSEQDLMQPEEPDYLLD-EMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSNEKS 514
Query: 771 VYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERE 830
+ KL +++ ++ L + + + Y E +E + ++ + + +
Sbjct: 515 L---KLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQ 571
Query: 831 RAE--RAKREEELREYQERVKKLEEVERKKRQRELEIEERE-----RRREEERRLGDSSL 883
A A +EE+ +E+ + ++E+E E R+E+ L D
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLT 631
Query: 884 SRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRS----HRRDEERPRR 939
+ + G S G GPE RG+G E+ S H +DEER +
Sbjct: 632 DKAEVSEGKAKSVGEAEDGPEG--------------RGDGTCEEGSSGAEHWQDEEREKG 677
Query: 940 LGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPR 999
D+ R RP + G + E++ + +R ++ R + R
Sbjct: 678 -EKDKGRGEMERPGE------------GEKELAEKEEWKKRDGEEQEQKEREQGHQKE-R 723
Query: 1000 RIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSS 1059
E+ G H + + E+ G +E G G ++ G G ++
Sbjct: 724 NQEMEEGGEEEHGEGE--------EEEGDREEEEEKEG--EGKEEGEGEEVEGEREKEEG 773
Query: 1060 WRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGP 1119
R ++ G +++G G D+G G +++ R ++ G G + + G
Sbjct: 774 ERKKEERAGK-----EEKGEEEG---DQG--EGEEEETEGRGEEKEEGGEVEGGEVEEGK 823
Query: 1120 WRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWR 1179
+++ E+ G + + + G+ G G
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE-------EGEG 876
Query: 1180 EKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRF 1239
E E+ E G EE E + E E + + + EE + E E + + E+
Sbjct: 877 EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936
Query: 1240 RRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPP 1299
E G G EE W + + + E + + E ++ + G
Sbjct: 937 GEGEGEDGEGEGE-EEEGEWEG-----EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990
Query: 1300 LRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAE 1359
E EE + + + E + V + E + + E EGE+E E
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEE-EGEEEGEEREKE 1049
Query: 1360 KDRESLRRTKNE-TDEDG 1376
+ E RR + E +E+G
Sbjct: 1050 GEGEENRRNREEEEEEEG 1067
Score = 48.9 bits (115), Expect = 3e-05
Identities = 79/380 (20%), Positives = 156/380 (41%), Gaps = 16/380 (4%)
Query: 576 EERKERLESLNIQREKE-----ELEQREAELQKVRKAEEERLRQEAKER------EKERI 624
+E+KER + +R +E E E E E ++ + EEE E KE E ER
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGERE 769
Query: 625 LQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKEL 684
+E E+ K++ + + ++ + G ++ + E+ + + +VE+ + E++E
Sbjct: 770 KEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEE 829
Query: 685 QERLKNQEKKIDYFERAKRLEEIPLIKSAYEE----QRIKDMDLWEQQEEERITTMQLER 740
+E + +E++ + E EE EE + ++ + E + EE + E
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889
Query: 741 EKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKE 800
E E + + + + + EE+ ++ E EE E + +
Sbjct: 890 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGE-GEEEEGEGEGEDGEGEG 948
Query: 801 ERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQ 860
E + +EEE + EE+ E EE E + E E +E ++ EE + +
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Query: 861 RELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRR 920
E E EE E E G+ + G+ + E ++G ++ R E+E +
Sbjct: 1009 GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGK 1068
Query: 921 GEGRDEDRSHRRDEERPRRL 940
+ E+ + R+D E +++
Sbjct: 1069 YQETGEEENERQDGEEYKKV 1088
Score = 42.4 bits (98), Expect = 0.003
Identities = 95/418 (22%), Positives = 175/418 (41%), Gaps = 41/418 (9%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEE--RKERLESLNIQREKEELEQREAEL 601
++ EEQ Q K + HQ+ R Q +EE +E E + ++EE E++E E
Sbjct: 705 RDGEEQEQ-------KEREQGHQK--ERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEG 755
Query: 602 QKVRKAEE---ERLRQEAKEREKERILQEHEQIKKKTVRERLEQI------KKTELGAKA 652
++ + EE ER ++E + +++ER +E + ++ E E+ +K E G
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVE 815
Query: 653 FKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQ-ERLKNQEKKIDYFERAKRLEEIPLIK 711
+++ E + + + E+ E E++E + E + + K + E + EE +
Sbjct: 816 GGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGE 875
Query: 712 SAYEEQRIK----DMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAA 767
EE+ + + E +EEE + E E E + + E+ + +
Sbjct: 876 GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE------EGE 929
Query: 768 RQSVYEEKLKQFE--ERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKE 825
+ EE + E E EE E + + + E E EE E EE+ E
Sbjct: 930 GEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGE 989
Query: 826 REERERAERAKREEELREYQERVKKLEE-------VERKKRQRELEIEERERRREEERRL 878
EE E E + E E E E + EE VE ++ + E E EE E EER
Sbjct: 990 GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE-EGEEREK 1048
Query: 879 GDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEER 936
+ +R + + EG +++ E ++E + G K+ + +G + H+ +++
Sbjct: 1049 EGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106
Score = 39.7 bits (91), Expect = 0.020
Identities = 68/361 (18%), Positives = 123/361 (34%), Gaps = 56/361 (15%)
Query: 1042 MDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDR--GP 1099
+ DD + ++ + S A+D GP + RG + G D++R G
Sbjct: 626 LSDDLTDKAEVSEGKAKSVGEAED--GP-----EGRGDGTCEEGSSGAEHWQDEEREKGE 678
Query: 1100 R-RGMDDDRGPRRGLDD--DRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDR 1156
+ +G + P G + ++ W+ D + ++ E RN + + +
Sbjct: 679 KDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEG 738
Query: 1157 FPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKER-DRDNQD 1215
GD RE+E+ +E G +E EE E +REKE +R ++
Sbjct: 739 EEEEGD----------------REEEEEKE---GEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 1216 REENDKDPERERDRERDVDREDRFR-RPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274
R ++ E E D+ + E R ++EGG G E ++ + ++
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Query: 1275 RERDDRRDLRERRDLRDDRDRRGPPLRSERE------------------EVSSWRRADDR 1316
E ++ E + + G E E E ++
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899
Query: 1317 KDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDG 1376
+ EE + E + E EGE+E+ E D E + E +E
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE-DGEG----EGEEEEGE 954
Query: 1377 W 1377
W
Sbjct: 955 W 955
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 99.4 bits (246), Expect = 2e-20
Identities = 98/389 (25%), Positives = 191/389 (49%), Gaps = 53/389 (13%)
Query: 575 IEERKERLESLNIQREKE---ELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQI 631
+EE K L S I + ++ +LE+ + + +K R+ E+ R+ +ERE+ER +E E+
Sbjct: 269 MEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERE 328
Query: 632 KKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQ 691
++ RER E+ K+ E + +D D + +E D D E+++ +ER ++
Sbjct: 329 RE---RER-EREKEKERERERERDRDRDRTKERDRD-------RDRERDRDRDRERSSDR 377
Query: 692 EKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMS 751
K +R++ E+ + E +R ++ + ++E ER + ERE+ E +
Sbjct: 378 NK-----DRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRD 432
Query: 752 RMLEDRDLF----VMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYY 807
R ++ D + + R +++ Y+E+LK +E R E + R E++ +R+EERR
Sbjct: 433 REEDEEDAYERRKLERKLREKEAAYQERLKNWEIR--ERKKTREYEKEAEREEERR---- 486
Query: 808 REKEEEEQRRAE--EQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEI 865
RE +E +R E E +R++ + + ++ LR+ R K++E ER +++ + E+
Sbjct: 487 REMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRD---REKEMEADERDRKREKEEL 543
Query: 866 EE-RERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGR 924
EE R+R E D+ L R E ++E RR P K+ E
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRM-----------------EQEAERRRQPQIKQEPESEEE 586
Query: 925 DEDRSHRRDE-ERPRRLGDDEDREPSLRP 952
+E++ + ++ E P ++ +++P L+P
Sbjct: 587 EEEKQEKEEKREEPMEEEEEPEQKPCLKP 615
Score = 99.0 bits (245), Expect = 3e-20
Identities = 123/492 (25%), Positives = 210/492 (42%), Gaps = 48/492 (9%)
Query: 534 LEVIKPAHILQEKEEQHQLAVTAYLK------NSRKEHQRILARRQTIEERKERLESLNI 587
L ++ H LQ E++ + V A K ++K+ AR +T+ E E+L+
Sbjct: 141 LRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDE--EALD- 197
Query: 588 QREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTE 647
EE ++R+ Q ++ A E +R+ + E QE + +K +E+ E I +
Sbjct: 198 ----EETKRRD---QMIKGAIEVLIREYSSELNAPS--QESDSHPRKKKKEKKEDIFRRF 248
Query: 648 LGAKAF-------KDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFER 700
A +DI+ ++EE D I ++++ + K+L+E +EK+ E+
Sbjct: 249 PVAPLIPYPLITKEDINAIEMEEDKRDLI-SREISKFRDTHKKLEEEKGKKEKERQEIEK 307
Query: 701 AKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLE----- 755
+R E + +R ++ + ++E+E+ + ER++ + R +
Sbjct: 308 ERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 756 DRDLFVMRLKAARQSVYEEKLKQFE-ERLAEERHNRLEERKRQRKEERRITYYREKEEEE 814
DRD + +S EK + E ER E R ER+R+R+ ER RE+E E
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERE----RERERER 423
Query: 815 QRRAEEQMLKEREERERAERAKREEELRE----YQERVKKLEEVERKK-RQRELEIEERE 869
+R +++ +E +E + ER K E +LRE YQER+K E ERKK R+ E E E E
Sbjct: 424 EREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREE 483
Query: 870 RRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRS 929
RR E + + DRD +R G R E E + RD R
Sbjct: 484 ERRREMAKEAKRLKEFLEDYDDDRDDPKYYR-GSALQKRLRDREKEME---ADERDRKRE 539
Query: 930 HRRDEERPRRLGDDEDREPSL---RPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDR 986
EE +RL + +P R + + RR + P EE+ + +
Sbjct: 540 KEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREE 599
Query: 987 PSWRNTDDDRPP 998
P + ++ P
Sbjct: 600 PMEEEEEPEQKP 611
Score = 95.5 bits (236), Expect = 3e-19
Identities = 69/194 (35%), Positives = 97/194 (50%), Gaps = 30/194 (15%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDRED 1237
+R+ K EE G + R E+E RE+ER+R+ ++RE +++ ERER+RER+ ++E
Sbjct: 284 FRDTHKKLEEEKGKKEKERQEIEKE-RRERERERE-RERERREREREREREREREKEKER 341
Query: 1238 RFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRG 1297
R RD RD R +RDRD R RERD RD D DR R
Sbjct: 342 ERERERD---------------RDRDRTKERDRD-RDRERDRDRDRERSSDRNKDRSRSR 385
Query: 1298 PPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWR 1357
R E R +R+ +R ER+ R R+RER+R+RERE EK+K R
Sbjct: 386 EKSRDRERE-----RERERERERERERERERE-------REREREREREREREKDKKRDR 433
Query: 1358 AEKDRESLRRTKNE 1371
E + ++ R K E
Sbjct: 434 EEDEEDAYERRKLE 447
Score = 93.6 bits (231), Expect = 1e-18
Identities = 89/354 (25%), Positives = 173/354 (48%), Gaps = 33/354 (9%)
Query: 529 VLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQ 588
++++ + + H E+E+ + ++ R+E +R R+ ER+ER +
Sbjct: 276 LISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERER---ERERERERRER------E 326
Query: 589 REKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEL 648
RE+E +RE E ++ R+ E +R R KER+++R + E+ + + ++ K
Sbjct: 327 REREREREREKEKERERERERDRDRDRTKERDRDR---DRERDRDRDRERSSDRNKDRSR 383
Query: 649 GAKAFKDIDIEDLEELDPDFIMAKQVE-QLEKEKKELQERLKNQEKK-------IDYFER 700
+ +D + E E + + ++ E + E+E++ +ER + ++KK D +ER
Sbjct: 384 SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 701 AKRLEEIPLIKSAYEEQRIKDMDLWEQQ-----EEERITTMQLEREKALEHKNRMSRMLE 755
K ++ ++AY+E R+K+ ++ E++ E+E + RE A E K R+ LE
Sbjct: 444 RKLERKLREKEAAYQE-RLKNWEIRERKKTREYEKEAEREEERRREMAKEAK-RLKEFLE 501
Query: 756 DRDLFVMRLKAARQSVYEEKLKQFEERL-AEERHNRLEERKRQRKEERRITYYREKEEEE 814
D D K R S +++L+ E+ + A+ER +RKR+++E I E
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADER-----DRKREKEELEEIRQRLLAEGHP 556
Query: 815 QRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEER 868
AE Q +++ ER R + K+E E E +E ++ EE + + E E E++
Sbjct: 557 DPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 89.7 bits (221), Expect = 2e-17
Identities = 77/301 (25%), Positives = 139/301 (46%), Gaps = 35/301 (11%)
Query: 1071 RGLDDDRGPRRGMDDDRGP----RRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDD 1126
R + R + +++++G R+ ++ +R R + RR + +R R + +
Sbjct: 279 REISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKE 338
Query: 1127 RIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKARE 1186
+ R E DR D DR R D DR R D R++E++ +
Sbjct: 339 KERERERERDR------DRDRTKER-DRDRDRERDRD---------------RDRERSSD 376
Query: 1187 ESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEG 1246
+ R S +RE +RE+ER+R+ + E +++ ERER+RER+ +RE +R R+E
Sbjct: 377 RNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREED 436
Query: 1247 GWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREE 1306
EE + R R R+++ +ER ++RER+ R+ RE
Sbjct: 437 -------EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREM 489
Query: 1307 VSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLR 1366
+R + +D ++RD P+ AL + R RDR++E E + E+ R +++ E +R
Sbjct: 490 AKEAKRLKEFLEDYDDDRDDPKYYRGSALQK-RLRDREKEMEAD-ERDRKREKEELEEIR 547
Query: 1367 R 1367
+
Sbjct: 548 Q 548
Score = 85.1 bits (209), Expect = 4e-16
Identities = 58/208 (27%), Positives = 100/208 (48%), Gaps = 15/208 (7%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDR 1238
+E EK R E R ERE +RE+ER+R+ + E +++ +R+RDR ++ DR+
Sbjct: 303 QEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD 362
Query: 1239 FRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGP 1298
R RD R + + + R SR RDR +R RER+ R+ R+ +R+R
Sbjct: 363 RERDRDRD---RERSSDRNKDRSRSREKSRDR-ERERERERERERERERERERERERERE 418
Query: 1299 PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALS----------RDRERDRDRERE 1348
R E R ++ ++D E R R++ + R+R++ R+ E+E
Sbjct: 419 REREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKE 478
Query: 1349 GEKEKASWR-AEKDRESLRRTKNETDED 1375
E+E+ R K+ + L+ + D+D
Sbjct: 479 AEREEERRREMAKEAKRLKEFLEDYDDD 506
Score = 82.8 bits (203), Expect = 2e-15
Identities = 95/402 (23%), Positives = 154/402 (38%), Gaps = 64/402 (15%)
Query: 828 ERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKD 887
E E +R E+ ++++ KKLEE + KK + EIE+ R RE ER R+
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
Query: 888 SRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDRE 947
R +R+ R E+E R RD DR+ RD +R R D DRE
Sbjct: 328 ERERERE---------------REKEKERERERERDRDRDRTKERDRDRDRERDRDRDRE 372
Query: 948 PSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRG 1007
S + DR R DR R E +R R +R R + +R
Sbjct: 373 RSSDRNKDRSRSREKSRDRERERERERERERER--------------ERERERERERERE 418
Query: 1008 NWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSW--RNADD 1065
R + ++ +R +ED +ED RR ++ + + +W R
Sbjct: 419 REREREREKDKKRDREED-------EEDAYERRKLERKLREKEAAYQERLKNWEIRERKK 471
Query: 1066 DRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADD 1125
R + + + RR M + + +D DDDR DD + +A
Sbjct: 472 TREYEKEAEREEERRREMAKEAKRLKEFLED------YDDDR------DDPKYYRGSALQ 519
Query: 1126 DRIPRRGAEDDRGPWRNMDDDRLSRRADDDRF----PRRGDDSRPGPWRPLVKPGGWREK 1181
R+ R E M+ D R+ + + R + P P L + +E
Sbjct: 520 KRLRDREKE--------MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRME--QEA 569
Query: 1182 EKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDP 1223
E+ R+ ES EE + ++E++R+ ++ EE ++ P
Sbjct: 570 ERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611
Score = 82.0 bits (201), Expect = 4e-15
Identities = 86/344 (25%), Positives = 140/344 (40%), Gaps = 69/344 (20%)
Query: 1067 RGPRRGLDDDRGP----RRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRN 1122
R + L++++G R+ ++ +R R + RR + +R R + ++ R
Sbjct: 285 RDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERE 344
Query: 1123 ADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKE 1182
+ DR R E DR R D DR R+ D R D SR REK
Sbjct: 345 RERDRDRDRTKERDRDRDRERDRDRDRERSSD----RNKDRSRS------------REKS 388
Query: 1183 KAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRP 1242
+ RE RE ERE +RE+ER+R+ + E +++ E+++ R+R+ D ED + R
Sbjct: 389 RDRERE----REREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444
Query: 1243 RDEGGWRRGPA---EESSSWRDSSRRDDRD-------RDDRRRE---------------- 1276
+ E R A E +W R+ R+ ++RRRE
Sbjct: 445 KLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYD 504
Query: 1277 --RDD-----------RRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVE- 1322
RDD R RE+ D+RDR+ + E EE+ A+ D E
Sbjct: 505 DDRDDPKYYRGSALQKRLRDREKEMEADERDRKRE--KEELEEIRQRLLAEGHPDPDAEL 562
Query: 1323 ---ERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRE 1363
E++ RR P + + E++ ++EK E++ E
Sbjct: 563 QRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEE 606
Score = 80.5 bits (197), Expect = 1e-14
Identities = 105/434 (24%), Positives = 179/434 (41%), Gaps = 69/434 (15%)
Query: 611 RLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDP---- 666
RL + + EK+ +++ K K + + KK G + + +D E LD
Sbjct: 145 RLLHDLQIGEKKLLVKV--DAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKR 202
Query: 667 -DFIMAKQVEQLEKE----------KKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYE 715
D ++ +E L +E + + R K +EKK D F +R PLI
Sbjct: 203 RDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIF---RRFPVAPLIP---- 255
Query: 716 EQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEK 775
+ +E I +++E +K R L R+ + + + + + EEK
Sbjct: 256 ---------YPLITKEDINAIEMEEDK---------RDLISRE--ISKFRDTHKKLEEEK 295
Query: 776 LKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE-------- 827
K+ +ER E+ R ER+R+R+ ERR RE+E E +R E++ +ERE
Sbjct: 296 GKKEKERQEIEKERRERERERERERERR-EREREREREREREKEKERERERERDRDRDRT 354
Query: 828 ---ERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEER-RLGDSSL 883
+R+R R+ + +R K K R RE E ERER RE ER R +
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERE-RERERERERERERERERER 413
Query: 884 SRKDSRWGDRDSEGTWRKGPEADSE--WRRGPPEKEWRRGEGRDEDRSHR---RDEERPR 938
R+ R +R+ E ++ E D E + R E++ R E ++R R+ ++ R
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTR 473
Query: 939 RLGDDEDREPSLRPDDDRVPRR------GMDDDRGPRRGPEEDRFSRRGADDDRPSWRNT 992
+ +RE R + + +R DDDR + +R D ++ +
Sbjct: 474 EYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADE 533
Query: 993 DDDRPPRRIADEDR 1006
D + + +E R
Sbjct: 534 RDRKREKEELEEIR 547
Score = 75.5 bits (184), Expect = 3e-13
Identities = 112/467 (23%), Positives = 180/467 (38%), Gaps = 69/467 (14%)
Query: 908 EWRRGPPEKEWRRGEGRDE----DRSHRRDEERPRRLGDDEDR---EPSLRPDDDRVPRR 960
EW+ +K+ G R E D DEE RR D + E +R +
Sbjct: 171 EWKA---KKKASNGNARPETVTNDDEEALDEETKRR--DQMIKGAIEVLIREYSSELNAP 225
Query: 961 GMDDDRGPRRGPEE---DRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNW-RHADDDR 1016
+ D PR+ +E D F R P T +D + ++ R R R
Sbjct: 226 SQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFR 285
Query: 1017 PPRRGLDEDRGS-----WRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRR 1071
+ L+E++G E R R + +R R + ER R + +R R
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Query: 1072 GLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRR 1131
D DR + D DR R D DR + DR R DR R + +R R
Sbjct: 346 ERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER 405
Query: 1132 GAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREE---S 1188
E +R R + +R R D + R D+ R L + REKE A +E +
Sbjct: 406 EREREREREREREREREREREKDKKRDREEDEEDAYERRKLERK--LREKEAAYQERLKN 463
Query: 1189 WGPPRESRPSE-EREWDREKERDRDN-----------QDREENDKDPE---------RER 1227
W + E E+E +RE+ER R+ +D +++ DP+ R R
Sbjct: 464 WEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLR 523
Query: 1228 DRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERR 1287
DRE++++ ++R R+ E EE + D D + +R E++ R
Sbjct: 524 DREKEMEADERDRKREKE------ELEEIRQRLLAEGHPDPDAELQRMEQEAER------ 571
Query: 1288 DLRDDRDRRGPPLRSE---REEVSSWRRADDRKDDRVEERDPPRRVP 1331
RR P ++ E EE + ++++++ +EE + P + P
Sbjct: 572 -------RRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611
Score = 62.4 bits (150), Expect = 3e-09
Identities = 54/233 (23%), Positives = 97/233 (41%), Gaps = 45/233 (19%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKERDRD----------------NQDREENDK 1221
W+ K+KA + P + EE + K RD+ N +E+D
Sbjct: 172 WKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDS 231
Query: 1222 DPERERDRERDVDREDRFRR-------------------PRDEGGWRRGPAEESSSWRDS 1262
P +++ ++ ED FRR E R + E S +RD+
Sbjct: 232 HPRKKKKEKK----EDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDT 287
Query: 1263 SRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVE 1322
++ + ++ + +ER + R R+ +R+R ERE + +R+ +R
Sbjct: 288 HKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERER 347
Query: 1323 ERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDED 1375
+RD R RDR+RDR+R+R+ ++E++S R KDR R + + +
Sbjct: 348 DRDRDR-----TKERDRDRDRERDRDRDRERSSDR-NKDRSRSREKSRDRERE 394
Score = 42.7 bits (99), Expect = 0.002
Identities = 43/198 (21%), Positives = 76/198 (38%), Gaps = 28/198 (14%)
Query: 1202 EWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRP------RDEGGWRRGPAEE 1255
EW +K+ N E D E D E R D+ + R+ P++E
Sbjct: 171 EWKAKKKASNGNARPETVTNDDEEALDEE--TKRRDQMIKGAIEVLIREYSSELNAPSQE 228
Query: 1256 SSSWRDSSRRDDRDRDDRRRE-----------RDDRRDLRERRDLRDDRDRRGPPLRSER 1304
S S +++ ++ RR ++D + D RD R R
Sbjct: 229 SDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTH 288
Query: 1305 EEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRES 1364
+++ + +++ +E+ RR R+RER+R+RER + + E+++E
Sbjct: 289 KKLEEEKGKKEKERQEIEKE---RR------ERERERERERERREREREREREREREKEK 339
Query: 1365 LRRTKNETDEDGWTTVRR 1382
R + E D D T R
Sbjct: 340 ERERERERDRDRDRTKER 357
Score = 34.3 bits (77), Expect = 0.85
Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 2/103 (1%)
Query: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL- 601
LQ++ + + A ++ ++E + + RQ + +QR ++E E+R
Sbjct: 518 LQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQI 577
Query: 602 -QKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQI 643
Q+ EEE +QE +E+ +E + +E E +K ++ L I
Sbjct: 578 KQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPI 620
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 99.4 bits (246), Expect = 2e-20
Identities = 83/377 (22%), Positives = 188/377 (49%), Gaps = 57/377 (15%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREK 621
R++ ++ + + E++ ++ Q ++E + RE E Q VR+ E + QE + RE+
Sbjct: 104 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQ 162
Query: 622 ERILQEHE-QIKKKT--VRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLE 678
E ++E E Q++++ VRE+ Q+++ E G ++ + + EE M +Q EQ++
Sbjct: 163 EGQVREQEGQVREQEGQVREQEGQVREQE-GQMGEQEGQMGEQEEQ-----MGEQEEQMQ 216
Query: 679 KEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL 738
K+++++ E+ + K +E+++ + + Q++EE++ +
Sbjct: 217 KQEEQMGEQEEQMRK---------------------QEEQMGEQEEQVQKQEEQVQKQEE 255
Query: 739 EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQR 798
+ K E + +++ E+ LKQ E+ EE+ EE+ R++
Sbjct: 256 QMRKQEEQMREQEEQMREQE--------------EQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 799 KEERRITYYREKEEEEQRRAEEQMLKEREER----------ERAERAKREEELREYQERV 848
+E+ R + +E+EEQ R +E+ + ++EE+ ++ + K+EE++ E +E++
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 849 KKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSE 908
+K EE RK+ ++ + EE+ R++EE+ R + + + + G++ + R+ E E
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ--MREQEEQMGE 419
Query: 909 WRRGPPEKEWRRGEGRD 925
+ ++E GE ++
Sbjct: 420 QKEQMRKQEEHMGEQKE 436
Score = 90.9 bits (224), Expect = 8e-18
Identities = 96/427 (22%), Positives = 219/427 (51%), Gaps = 27/427 (6%)
Query: 532 KALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREK 591
K E+ + +++ ++ + QL + LK + + L + + E++ ++ Q +
Sbjct: 12 KNAELQEELQLVETEKSEIQLHIKE-LKRKLETDKIPLPQEGQVREQEGQVREQEGQVRE 70
Query: 592 EELEQREAELQKVRKAEEERLRQEAKEREKERILQEHE-QIKKKT--VRERLEQIKKTEL 648
+E + RE E Q VR+ E + QE + RE+E ++E E Q++++ VRE+ Q+++ E
Sbjct: 71 QEGQVREQEGQ-VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE- 128
Query: 649 GAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIP 708
G ++ + + E + QV + E + +E + +++ QE ++ E R +E
Sbjct: 129 GQVREQEGQVREQEGQVRE--QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE-G 185
Query: 709 LIKSAYEEQRIKDMDLWEQQEE--ERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKA 766
++ + ++ + EQ+E+ E+ MQ + E+ E + +M + E M +
Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ-----MGEQE 240
Query: 767 ARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQR--RAEEQMLK 824
+ EE++++ EE++ ++ E+ ++ R++E ++ +E+ E+E++ EEQM +
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 825 EREE-RERAERAK-REEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSS 882
+ E+ RE+ E+ + +EE++RE +E++ K E E+ Q+E E++E+ ++E ++G+
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQE--EQMWEQKEQMWEQKEQMWKQEEQMGEQE 358
Query: 883 LSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRD---EDRSHRRDEERPRR 939
+ R E RK E + ++E + GE ++ E + R++E +
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQE--EQ 416
Query: 940 LGDDEDR 946
+G+ +++
Sbjct: 417 MGEQKEQ 423
Score = 86.3 bits (212), Expect = 2e-16
Identities = 83/398 (20%), Positives = 206/398 (51%), Gaps = 28/398 (7%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREK 621
R++ ++ + + E++ ++ Q ++E + RE E Q VR+ E + QE + RE+
Sbjct: 55 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQ 113
Query: 622 ERILQEHE-QIKKKT--VRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLE 678
E ++E E Q++++ VRE+ Q+++ E G ++ + + E QV + E
Sbjct: 114 EGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQVREQEG---------QVREQE 163
Query: 679 KEKKELQERLKNQEKKIDYFERAKRLEEIPLIKS----AYEEQRIKDMDLWEQQEEERIT 734
+ +E + +++ QE ++ E R +E + + +E+++ + + Q++EE++
Sbjct: 164 GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG 223
Query: 735 TMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEER 794
+ + K E ++ ++ V + + + EE++++ EE++ E+ L+++
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK-QEEQMREQEEQMREQEEQMLKQK 282
Query: 795 KRQRKEERRITYYRE-KEEEEQRRAEEQMLKEREERERAER---AKREEELREYQERVKK 850
++ +EE+ + +E+EEQ R +E+ ++E+EE+ R + K+EE++ E +E++ +
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 851 LEEVERKKRQRELEIEERERRREEER-RLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEW 909
+E + K++ ++ +E + +++EE+ R + + +++ + R E RK E E
Sbjct: 343 QKE-QMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM--RKQEEQMRKQEEQMGEQ 399
Query: 910 RRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDRE 947
+ E++ + E ++E ++++ R + E +E
Sbjct: 400 KEQMGEQKEQMRE-QEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 57.4 bits (137), Expect = 9e-08
Identities = 74/455 (16%), Positives = 210/455 (46%), Gaps = 42/455 (9%)
Query: 623 RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE-ELDPDFIMAKQVEQLEKEK 681
RI E + K ++E L Q+ +TE K+ + I++L+ +L+ D I Q Q+ +++
Sbjct: 3 RITNEELKEKNAELQEEL-QLVETE---KSEIQLHIKELKRKLETDKIPLPQEGQVREQE 58
Query: 682 KELQER---LKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL 738
+++E+ ++ QE ++ E R +E + + +E ++++ + +++E ++
Sbjct: 59 GQVREQEGQVREQEGQVREQEGQVREQEGQVRE---QEGQVREQEGQVREQEGQVR---- 111
Query: 739 EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQR 798
E+E + + R E + +R + + E ++++ E ++ E+ E+ + R
Sbjct: 112 EQEGQVREQEGQVREQEGQ----VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 167
Query: 799 KEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKK 858
++E ++ +E+E Q R +E ++E+E + ++E ++ E +E++ + EE +K+
Sbjct: 168 EQEGQV-----REQEGQVREQEGQVREQE----GQMGEQEGQMGEQEEQMGEQEEQMQKQ 218
Query: 859 RQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEW 918
++ E EE+ R++EE+ + + +++ + ++ + ++ + E + E++
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
Query: 919 RRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFS 978
+ + + E ++E R +++ RE + + R ++ G + EE +
Sbjct: 279 LKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ---EEQMWE 335
Query: 979 RRGA--DDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDR 1036
++ + W+ + ++ +++ + + R + + R +E
Sbjct: 336 QKEQMWEQKEQMWKQEE------QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ- 388
Query: 1037 GPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRR 1071
R ++ G ++ +++ R ++ G ++
Sbjct: 389 --MRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421
Score = 45.4 bits (106), Expect = 4e-04
Identities = 27/200 (13%), Positives = 91/200 (45%), Gaps = 5/200 (2%)
Query: 1177 GWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDRE 1236
G +E++ +E +E + E+ E R++E Q+ + ++ + ++ E+ +E
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 1237 DRFRRPRDEGGWRRGPAEESSSWRDSSRRDDR--DRDDRRRERDDRRDLRERRDLRDDRD 1294
++ R ++ R E+ ++ + ++++ +++++ RE++++ +E + +
Sbjct: 262 EQMREQEEQ---MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318
Query: 1295 RRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKA 1354
R + ++E W + + + + + ++ ++ ++ R++E + K
Sbjct: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
Query: 1355 SWRAEKDRESLRRTKNETDE 1374
+ K E +R+ + + E
Sbjct: 379 EEQMRKQEEQMRKQEEQMGE 398
Score = 42.7 bits (99), Expect = 0.002
Identities = 32/189 (16%), Positives = 84/189 (44%), Gaps = 4/189 (2%)
Query: 1176 GGWREKEKAREESWGPPRESRPS--EEREWDREKERDRDNQDREENDKDPERERDRERDV 1233
G RE+E E G RE E+ E+E Q+ + +++ + ++ E+
Sbjct: 164 GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG 223
Query: 1234 DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDR 1293
++E++ R+ ++ G + ++ R ++++ RE++++ +E + L+
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283
Query: 1294 DRRGPPLRSEREEVSSWRRADDR-KDDRVEERDPPRRVPPPALSRDRERD-RDREREGEK 1351
E+EE + R +++++ E++ R + + E+ +E+ E+
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ 343
Query: 1352 EKASWRAEK 1360
++ W+ E+
Sbjct: 344 KEQMWKQEE 352
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/192 (21%), Positives = 91/192 (47%), Gaps = 33/192 (17%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILAR----- 571
EQ+R Q M + E + +L++KE+ Q T + +E + +
Sbjct: 255 EQMRKQEEQMREQEEQMRE--QEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQM 312
Query: 572 RQTIEERKERLESLNIQRE------------KEELEQREAEL----QKVRKAEEERLRQE 615
R+ E+ +E+ E + Q E KE++ ++E ++ ++++K EE+ +QE
Sbjct: 313 REQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQE 372
Query: 616 AKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVE 675
+ R++E +++ E+ +K + EQ K ++G + E + E + M +Q E
Sbjct: 373 EQMRKQEEQMRKQEEQMRKQEEQMGEQ--KEQMGEQK------EQMREQEEQ--MGEQKE 422
Query: 676 QLEKEKKELQER 687
Q+ K+++ + E+
Sbjct: 423 QMRKQEEHMGEQ 434
Score = 40.0 bits (92), Expect = 0.016
Identities = 27/175 (15%), Positives = 75/175 (42%), Gaps = 18/175 (10%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDR 1238
++KE+ +E +E + E+ E RE+E Q+ E+ R++E + +++
Sbjct: 280 KQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE--------EQMREQEEQMGKQEE 331
Query: 1239 FRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGP 1298
+ E W ++ W+ + +++ +++E R+ + R + ++
Sbjct: 332 QMWEQKEQMWE----QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEE 387
Query: 1299 PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEK 1353
+R + E++ ++K+ E+++ R + + + E GE+++
Sbjct: 388 QMRKQEEQMG------EQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 38.1 bits (87), Expect = 0.059
Identities = 47/229 (20%), Positives = 99/229 (43%), Gaps = 27/229 (11%)
Query: 1171 PLVKPGGWREKEKAREESWGPPRE------SRPSEEREWD---REKE---RDRDNQDREE 1218
PL + G RE+E E G RE + + RE + RE+E R+++ Q RE+
Sbjct: 47 PLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 106
Query: 1219 NDKDPERE---RDRERDV-DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRR 1274
+ E+E R++E V ++E + R + + G E R+++ +
Sbjct: 107 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 166
Query: 1275 RE-----RDDRRDLRERR-DLRDDRDRRGP---PLRSEREEVSSWRRADDRKDDRVEERD 1325
RE R+ +RE+ +R+ + G + + E++ ++++++ E++
Sbjct: 167 REQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQE 226
Query: 1326 PPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDE 1374
R + E+ + +E + +K++ R K E +R + + E
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR--KQEEQMREQEEQMRE 273
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 97.1 bits (240), Expect = 1e-19
Identities = 173/871 (19%), Positives = 353/871 (40%), Gaps = 109/871 (12%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
++ +++ A+ S + ++L + +++E+L + ++ EKE L + E L++
Sbjct: 662 EDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLE-EKEWLFKDEKSLKR 720
Query: 604 VRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEE 663
++ ++ R +E+++ ++ +K+K+ +E ++ K E K+ KD
Sbjct: 721 IKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKS-KD-------- 771
Query: 664 LDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAK-RLEEIPLIKSAYEEQRIKDM 722
+ +LEK+ ++++ +++KI ++ K + E++ SA++E K+
Sbjct: 772 ---------RPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQ 822
Query: 723 DLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEER 782
L + E+ + + +R++ + S + D + + R + K E
Sbjct: 823 FL--ENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILET 880
Query: 783 LAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELR 842
+ E+ R + + + K + R ++R+K+ + + E+ KE+ E+ ++ E+ +
Sbjct: 881 VKEDSKERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKR-KEQTEKHKSVPGYLSEKDK 939
Query: 843 EYQERVK----KLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRD-SEG 897
+ +E + + + +E K +R+ + E REE + G S G +D S+G
Sbjct: 940 KRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCES--------GFKDKSDG 991
Query: 898 TWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDR-EPSLRPDDDR 956
+ KG E W R P +E + +G D++R + ER + D+D+ E S+ +
Sbjct: 992 DFGKGLE---PWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEKSILEKCQK 1048
Query: 957 VPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDR 1016
+ D ++ +E G D +R + + ++ + ++ DD
Sbjct: 1049 --DKEFDKCFKEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDD- 1105
Query: 1017 PPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRR-GLDD 1075
++G ++ SW AD +DDR G S ++ + PR GL +
Sbjct: 1106 --KKGKEK---SWYIADIFTDE---SEDDRDSCMG------SGFKMGEASDLPRTDGLQE 1151
Query: 1076 DRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRG---PWRNADDDRIPRRG 1132
R DR R D + P R D + RR DRG R+ + +
Sbjct: 1152 KEEGREAYASDR--HRKSSDKQHPERQKDKEPRDRR---KDRGAADAGRDKKEKVFEKHK 1206
Query: 1133 AEDDRGPWRNMDD--DRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWG 1190
+ D+ D DR S + D+ ++ + + KEK+ +E
Sbjct: 1207 EKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSK 1266
Query: 1191 PPRESRPSEEREWDREK-ERDRDNQDREE-NDKDPERERDRERDVDRED--------RFR 1240
+ SR ++ + EK E + ++ RE+ NDK E D D +E F
Sbjct: 1267 ERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFT 1326
Query: 1241 RPRDEGGWRRGPA-------EESSSWRDSSRRDDRDRDDRRRERDDRR----DLRERRDL 1289
P + R +E SS + DR+ ++E+ +++ D +E
Sbjct: 1327 EPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSR 1386
Query: 1290 RDDRDRRGPPLRSEREEVSSWRRAD--------------DRKDDRVEERDPPRRV----P 1331
+D L ++ VS +AD ++KD ER+P +++
Sbjct: 1387 KDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELK 1446
Query: 1332 PPALSRDRERDRDREREGEKEKASWRAEKDR 1362
P S ++RE +EK WR EK+R
Sbjct: 1447 PYGSSAINILKEKKKREKHREK--WRDEKER 1475
Score = 79.7 bits (195), Expect = 2e-14
Identities = 146/759 (19%), Positives = 297/759 (39%), Gaps = 92/759 (12%)
Query: 634 KTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEK 693
K VR+R E K+ L K K + E P +L+KE K +++ +
Sbjct: 590 KPVRKRQEHRKRASLSEK--KSPFLSSAEGAVP---------KLDKEGKVVKKHKTKHKH 638
Query: 694 KIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRM 753
K + +E+ L YE +E +++ + LE + + E N++ +
Sbjct: 639 KNKEKGQCSISQELKLKSFTYE---------YEDSKQKSDKAILLENDLSTE--NKLKVL 687
Query: 754 LEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEE 813
DRD F EEKL + +LEE++ K+E+ + ++ ++
Sbjct: 688 KHDRDHFKK----------EEKLSKM----------KLEEKEWLFKDEKSLKRIKDTNKD 727
Query: 814 EQRRAEEQM---LKEREERERAERAKREEELREYQERVKKL-----EEVERKKRQRELEI 865
R E+ K +ER E++ +EE+LR Y+E KK ++E+K +E +I
Sbjct: 728 ISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKI 787
Query: 866 EERERR--REEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEG 923
+ + + +E++ +L + R+DS + + ++ + + D+++ +++ +
Sbjct: 788 SKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLE--NEDTKFSLSDDQRDRWFSDL 845
Query: 924 RDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGAD 983
D + ++ + D D + D V + ++ + + D +R D
Sbjct: 846 SDSSFDFKGEDSWDSPVTDYRDMK------SDSVAKLILETVKEDSKERRRDSRAREKRD 899
Query: 984 DDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMD 1043
P +R D D + +H P ++D+ +A+ R + ++
Sbjct: 900 YREPFFRKKDRDYLDKNSEKRKEQTEKHKS---VPGYLSEKDKKRRESAEAGRDRKDALE 956
Query: 1044 DDRGPRRGGADDE---RSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPR 1100
+ R G A E R + + G + D D G + P R + GP
Sbjct: 957 SCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPD 1016
Query: 1101 RGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRR 1160
+ + P R + +++D D+ + E + ++ + D+ + D + +
Sbjct: 1017 KERKEKTKPERYKE------KSSDKDKSEKSILEKCQ---KDKEFDKCFKEKKDTK-EKH 1066
Query: 1161 GDDSRPGPWRPLVKPGGWREKEKA----REESWGPPRESRPSEEREWDREKERDRDNQDR 1216
D R G +KEKA E + ++ + +E+ W +++D
Sbjct: 1067 KDTHGKDKERKASLDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDD 1126
Query: 1217 EENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRE 1276
++ + D+ R D + ++EG A S R SS + +R +
Sbjct: 1127 RDSCMGSGFKMGEASDLPRTDGLQE-KEEG----REAYASDRHRKSSDKQHPERQKDKEP 1181
Query: 1277 RDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKD----DRVEERDPPRRVPP 1332
RD R+D R D D+ + E+++ S + DRKD D +++ +++P
Sbjct: 1182 RDRRKD-RGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPE 1240
Query: 1333 PALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNE 1371
A + D+ + + KEK+ K+R+S R E
Sbjct: 1241 KAEKKHAAEDKAKSK--HKEKSDKEHSKERKSSRSADAE 1277
Score = 58.5 bits (140), Expect = 4e-08
Identities = 105/545 (19%), Positives = 210/545 (38%), Gaps = 49/545 (8%)
Query: 571 RRQTIEERKERLESLNIQREKEELE--QREAELQKVRK----AEEERLRQEAKEREKERI 624
+ +T ER + S + EK LE Q++ E K K +E+ K++E++
Sbjct: 1020 KEKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKAS 1079
Query: 625 LQEHEQIKKKT----VRERLEQIKKTELGA-KAFKDIDI-EDLEELDPDFIMAKQVEQLE 678
L + ++ K+K + E + K + G K++ DI D E D D M + E
Sbjct: 1080 LDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGE 1139
Query: 679 KEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL 738
+ L+ +E+ + + + + +R KD + +++++
Sbjct: 1140 ASDLPRTDGLQEKEEGREAYASDRHRKS----SDKQHPERQKDKEPRDRRKDRGAADAGR 1195
Query: 739 EREKALEHKNRMSRMLEDRDLFVMRL-KAARQSVYEEKLKQFEERLAEERHNRLEERKRQ 797
++++ + K++ + E + + R +A+ S ++K KQ AE++H ++ K +
Sbjct: 1196 DKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSK 1255
Query: 798 RKEERRITYYREKEEEEQRRAEEQMLKEREERERAE-RAKREEELREYQE---------- 846
KE+ + +E++ AE+ +L++ EE E R +++ E
Sbjct: 1256 HKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEP 1315
Query: 847 ------RVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWR 900
V E K + + E+ + +E R SS D ++
Sbjct: 1316 GLTAFLEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKE 1375
Query: 901 KG---PEADSEWRRGPPEKEWRRGEGRDEDRSHRRD-EERPRRLGDDEDREPSLRPDDDR 956
KG E S G EK++ + + + D E+ + + E + D +R
Sbjct: 1376 KGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSER 1435
Query: 957 VPRRGMDDDRGPRRGPEEDRF-SRRGADDDRPSWRNTDDDRPPRRIAD------EDRGNW 1009
P + ++ + P + ++ + R WR+ + +R R AD D
Sbjct: 1436 EPSKKIEKELKPYGSSAINILKEKKKREKHREKWRD-EKERHRDRHADGLLRHHRDELLR 1494
Query: 1010 RHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERS---SWRNADDD 1066
H D+ +P R D + D GPR G + + GA+ E+ N +D
Sbjct: 1495 HHRDEQKPATRDKDSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDK 1554
Query: 1067 RGPRR 1071
P +
Sbjct: 1555 VAPSK 1559
Score = 56.6 bits (135), Expect = 2e-07
Identities = 101/492 (20%), Positives = 201/492 (40%), Gaps = 75/492 (15%)
Query: 543 LQEKEEQHQL-AVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL 601
LQEKEE + A + K+S K+H ++ + RK+R + + +KE++ ++ E
Sbjct: 1149 LQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKVFEKHKEK 1208
Query: 602 QKVRKAEEERLR---------QEAKEREK--ERILQEHEQIKKKTVRERLEQIKKTELGA 650
+ E+ + R Q+ K ++K E+ ++H K + + + K+
Sbjct: 1209 KDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKER 1268
Query: 651 KAFKDIDIED--LEELDPDFIMAKQVEQLEKEKKELQERL--KNQEKKIDYF-------- 698
K+ + D E LE+L+ + + + + +K + + + QE + F
Sbjct: 1269 KSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEP 1328
Query: 699 ---ERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLE-REKALEHKNRMSRM- 753
++ + +P E R + + ER + E +EK ++K SR
Sbjct: 1329 PGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKD 1388
Query: 754 -------LEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITY 806
+ D + + + + +E K E E++ ER+ +K E+ +
Sbjct: 1389 SGQYEKDFLEADAYGVSYN-MKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKP 1447
Query: 807 YREKE---EEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQREL 863
Y +E+++ E+ K R+E+ER + LR +++ + + E+K R+
Sbjct: 1448 YGSSAINILKEKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDK 1507
Query: 864 EIEER---ERRREEERRLGDSSLSRK-----DSRWGD--RDSEGTWRKGPEADSEWRRGP 913
+ R ++ R+E RLGD+ L K + GD + S G + P D +
Sbjct: 1508 DSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKDPGKKDAR 1567
Query: 914 PEKEWRRGEG---------------RDEDRSHRRDEERPR-------RLGDDEDREPSLR 951
P +E G+G + + H+R +ER + R GD + +E +
Sbjct: 1568 P-REKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKLKEKAKP 1626
Query: 952 PDDDRVPRRGMD 963
DD R ++G+D
Sbjct: 1627 ADDGR--KKGLD 1636
Score = 45.4 bits (106), Expect = 4e-04
Identities = 56/250 (22%), Positives = 105/250 (42%), Gaps = 31/250 (12%)
Query: 1134 EDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGP---WRPLVKPGGWRE-KEKAREESW 1189
ED + + DR D F +G+DS P +R + + E +E+S
Sbjct: 827 EDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSK 886
Query: 1190 GPPRESRPSEEREWD----REKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDE 1245
R+SR E+R++ R+K+RD +++ E+ + E+ + + +D+ RR E
Sbjct: 887 ERRRDSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAE 946
Query: 1246 GGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSERE 1305
G R A ES RRD R + + R++ ++ +D D +
Sbjct: 947 AGRDRKDALESCK----ERRDGRAKPEEAH-REELKECGCESGFKDKSDG------DFGK 995
Query: 1306 EVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESL 1365
+ W R ++ E++D P D+ER + E KEK+S + + ++ L
Sbjct: 996 GLEPWERHHPAREK--EKKDGP----------DKERKEKTKPERYKEKSSDKDKSEKSIL 1043
Query: 1366 RRTKNETDED 1375
+ + + + D
Sbjct: 1044 EKCQKDKEFD 1053
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 96.7 bits (239), Expect = 1e-19
Identities = 115/461 (24%), Positives = 180/461 (39%), Gaps = 60/461 (13%)
Query: 629 EQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERL 688
E+ K + ++L K+ E+ + +D E+ + + K+ E++EK++++ E +
Sbjct: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
Query: 689 KNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKN 748
K +EK D + + +R MD + + + T +E++ + ++
Sbjct: 541 KKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQD 600
Query: 749 RMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYR 808
R S E RD+ +K+K+ ER ER+RQR+ E R T
Sbjct: 601 RKSESKEKRDILSF-----------DKIKEQRER----------ERQRQREREIRET--- 636
Query: 809 EKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEER 868
E+ E ++R EQ L+ ER+ R +RE E Q + + E +ER++ +RE ER
Sbjct: 637 ERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVER 696
Query: 869 ERRREEER--------RLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRR 920
ERR+E+ER R L + R R R+ E +R E +R
Sbjct: 697 ERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRA 756
Query: 921 GEGRDEDRSHRRDEERPRRLGDDE-DREPSLRP-DDDRVPRRGMDDDRGPRRGPEEDRFS 978
R + R H D + D DR RP D + DDR GP E
Sbjct: 757 DFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHRDGQHYGDDRHGHGGPPE---- 812
Query: 979 RRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGP 1038
R D R W D+ E RG PPR G D + R +
Sbjct: 813 -RHGRDSRDGWGGYGSDKR----LSEGRGL------PPPPRGGRDWGEHNQRLEEHQARA 861
Query: 1039 RRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGP 1079
+G D G A E + W +G RGL GP
Sbjct: 862 WQGAMD-----AGAASREHARW------QGGERGLSGPSGP 891
Score = 50.8 bits (120), Expect = 9e-06
Identities = 56/188 (29%), Positives = 88/188 (46%), Gaps = 25/188 (13%)
Query: 1162 DDSRPGPW-RPLVKPGGWREKEKA--REESWGPPRESRPSEEREWDRE-KERDRDNQDRE 1217
D+ +PGP R V G R E+ ++S G P S + R +R K +DR ++ +E
Sbjct: 548 DELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKE 607
Query: 1218 END----------KDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDD 1267
+ D ++ ER+R RER++ RE RR R++ R E+ R R
Sbjct: 608 KRDILSFDKIKEQRERERQRQREREI-RETERRREREQR--EREQRLEAFHERKEKARLQ 664
Query: 1268 RDR-----DDRRRERDD-RRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRV 1321
R+R +R ER+ R+ ER +R +R+RR R RE R+ + + +
Sbjct: 665 RERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYE-- 722
Query: 1322 EERDPPRR 1329
+ER P RR
Sbjct: 723 QERRPGRR 730
Score = 49.7 bits (117), Expect = 2e-05
Identities = 34/107 (31%), Positives = 59/107 (55%), Gaps = 6/107 (5%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
+E+E Q Q R+E ++ R Q +E ER E +QRE+ +LE + L++
Sbjct: 621 RERERQRQREREIRETERRREREQ-REREQRLEAFHERKEKARLQRERLQLECQRQRLER 679
Query: 604 VR----KAEEERLRQEAKER-EKERILQEHEQIKKKTVRERLEQIKK 645
R + E ER+R E + R E+ERI +E E+++++ + R EQ ++
Sbjct: 680 ERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERR 726
Score = 49.3 bits (116), Expect = 3e-05
Identities = 60/207 (28%), Positives = 82/207 (39%), Gaps = 35/207 (16%)
Query: 1180 EKEKAREESWGPPRESRPSEER-EWDREKERDRDNQDREENDKDPERERDRERDVDREDR 1238
E+E+ E RE R +ER +RE+ R + Q R E ++ P R R D+DR
Sbjct: 683 ERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGR---RPYDLDR--- 736
Query: 1239 FRRPRDEGGWRRGP--AEESSSWRDSSRRDDRDRDDRRRERD-------DRR-------- 1281
RD+ W G A E D R D R D R+R DRR
Sbjct: 737 ----RDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMG 792
Query: 1282 DLRERRDLRDDRD-RRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRE 1340
D R+ + DDR GPP R R+ W D R+ E R +PPP R+
Sbjct: 793 DHRDGQHYGDDRHGHGGPPERHGRDSRDGW--GGYGSDKRLSE---GRGLPPPPRG-GRD 846
Query: 1341 RDRDREREGEKEKASWRAEKDRESLRR 1367
+R E + +W+ D + R
Sbjct: 847 WGEHNQRLEEHQARAWQGAMDAGAASR 873
Score = 41.6 bits (96), Expect = 0.005
Identities = 36/168 (21%), Positives = 84/168 (50%), Gaps = 29/168 (17%)
Query: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERL--ESLNIQREKEELEQREA 599
++ +K + + S++ + R+ +E+++ L + + QRE+E QRE
Sbjct: 572 VVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQRER 631
Query: 600 ELQKV--RKAEEERLRQEAKE-----REKERILQEHEQI---KKKTVRERLEQIKKTELG 649
E+++ R+ E+R R++ E +EK R+ +E Q+ +++ RER+E+ +
Sbjct: 632 EIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERL---- 687
Query: 650 AKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKEL---QERLKNQEKK 694
+ E + + K+ E++ +E++EL QE+L+ ++++
Sbjct: 688 ----------ERERMRVERERRKEQERIHREREELRRQQEQLRYEQER 725
Score = 40.4 bits (93), Expect = 0.012
Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 26/142 (18%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDR 1238
RE+++ RE RE R +E R ++ER++ + E + +R+R + + R
Sbjct: 623 RERQRQRE------REIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQR 676
Query: 1239 FRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGP 1298
R R E R+ R +R R +R R ++ R RER +LR R+
Sbjct: 677 LERERME--------------RERLER-ERMRVERERRKEQERIHREREELR----RQQE 717
Query: 1299 PLRSEREEVSSWRRAD-DRKDD 1319
LR E+E R D DR+DD
Sbjct: 718 QLRYEQERRPGRRPYDLDRRDD 739
Score = 37.0 bits (84), Expect = 0.13
Identities = 39/184 (21%), Positives = 73/184 (39%), Gaps = 23/184 (12%)
Query: 1182 EKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKD---PERERDRERDVDREDR 1238
EKA+ E G R E + ++ DR + + +K E + +++ + ED
Sbjct: 481 EKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDI 540
Query: 1239 FRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGP 1298
+ +D+ + GP S + SR ER + D +G
Sbjct: 541 KKEEKDQDELKPGPTNRSRVTKSGSRG------------------MERTVVMDKS--KGE 580
Query: 1299 PLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRA 1358
P+ S + S R+ +D + E ++ + + RER+R R+RE E + R
Sbjct: 581 PVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRR 640
Query: 1359 EKDR 1362
E+++
Sbjct: 641 EREQ 644
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 94.7 bits (234), Expect = 5e-19
Identities = 74/249 (29%), Positives = 121/249 (48%), Gaps = 35/249 (14%)
Query: 1130 RRGAEDDRGPW----RNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAR 1185
R G+++ W + D D R+ + DR + + R + R++E+ R
Sbjct: 53 RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRK--------RDRERRR 104
Query: 1186 EESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRP--R 1243
+E +E+ + +RE E ERDR+ + ++ +++ +R R+RERD DRE R +
Sbjct: 105 KE-----KETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK 159
Query: 1244 DEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDR---RGPPL 1300
D G R E RD R ++R+ R +RD +RD + R+ + DR+R R
Sbjct: 160 DRDGQRETETERE---RDREREKQKERETER-DRDRQRDTEKERERQTDRERDRQRKTQT 215
Query: 1301 RSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDR--DREREGEKEKASWRA 1358
+RE R DR+ +R +RD + RDRERDR +R++E +KE+ R
Sbjct: 216 ERQRETDREGERETDRRRERQRDRDRGK-------ERDRERDRKEERKKERKKERKKERK 268
Query: 1359 EKDRESLRR 1367
EK +E RR
Sbjct: 269 EKKKEEKRR 277
Score = 79.7 bits (195), Expect = 2e-14
Identities = 64/199 (32%), Positives = 100/199 (50%), Gaps = 31/199 (15%)
Query: 1188 SWGPPRESRPSE----EREWDR-----EKERDRDNQ-DREENDKDPERERDRERDVDRED 1237
SWG + + ++ +RE DR EKERDRD + DRE K+ E R+R+R+ E
Sbjct: 62 SWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEI 121
Query: 1238 RFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRRRERDDRRDLRERRDLRDDRDRR 1296
R R++ ++G E RD R +RDRD ++ RER +D +R+ +R+R
Sbjct: 122 ERDREREK---QKGRERE----RDRGRERERDRDREKERERQTEKDRDGQRETETERER- 173
Query: 1297 GPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASW 1356
+RE R +R DR + + R DRERDR R+ + E+++ +
Sbjct: 174 ------DREREKQKERETERDRDRQRDTEKERE-----RQTDRERDRQRKTQTERQRETD 222
Query: 1357 RAEKDRESLRRTKNETDED 1375
R E +RE+ RR + + D D
Sbjct: 223 R-EGERETDRRRERQRDRD 240
Score = 77.4 bits (189), Expect = 9e-14
Identities = 66/261 (25%), Positives = 118/261 (45%), Gaps = 30/261 (11%)
Query: 1042 MDDDRGPRRGGADDERSSW----RNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDR 1097
+D RG R G+ + SW + D D R+ D + + DR +R DR
Sbjct: 47 LDFSRG--RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKR----DR 100
Query: 1098 GPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAED--DRGPWRNMDDDRLSRRADDD 1155
RR ++ R D ++ D +R ++G E DRG R D DR R
Sbjct: 101 ERRR---KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERE--- 154
Query: 1156 RFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQD 1215
R+ + R G + RE+EK +E R+ + E+E +R+ +R+RD Q
Sbjct: 155 ---RQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQR 211
Query: 1216 REENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRR 1275
+ + ++ E +R+ ER+ DR +R RD G R R+ R+++R ++ ++
Sbjct: 212 KTQTERQRETDREGERETDRRRERQRDRDRGKERD---------RERDRKEERKKERKKE 262
Query: 1276 ERDDRRDLRERRDLRDDRDRR 1296
+ +R++ ++ R+D+ R+
Sbjct: 263 RKKERKEKKKEEKRREDKKRK 283
Score = 77.0 bits (188), Expect = 1e-13
Identities = 75/254 (29%), Positives = 120/254 (47%), Gaps = 28/254 (11%)
Query: 1073 LDDDRGPRRGMDDDR--GPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPR 1130
LD RG + R G + D G R + DR R + +R R D +R R
Sbjct: 47 LDFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDR-VREKTEKERDRDRKRDRER--R 103
Query: 1131 RGAEDDRGPWRNMDDDRLSR-RADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESW 1189
R ++ RN D ++ + D +R ++G + R + R++EK RE
Sbjct: 104 RKEKETN---RNRDREKQTEIERDREREKQKGRERERDRGRERERD---RDREKERERQT 157
Query: 1190 GPPRESRPSEEREWDREKERDRDNQDREENDKDPERERD----RERDVDRE-DRFRRPRD 1244
R+ + E E +RE++R+R+ Q E ++D +R+RD RER DRE DR R+ +
Sbjct: 158 EKDRDGQ--RETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQT 215
Query: 1245 EGGWRRGPAEESSSWRDSSRRDDRDRD-DRRRERDDRRDLRERRDLRDDRDRRGPPLRSE 1303
E R + R++ RR +R RD DR +ERD RD +E R ++R+ +
Sbjct: 216 E----RQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKK 271
Query: 1304 REEVSSWRRADDRK 1317
+EE +R +D+K
Sbjct: 272 KEE----KRREDKK 281
Score = 75.5 bits (184), Expect = 3e-13
Identities = 63/233 (27%), Positives = 101/233 (43%), Gaps = 25/233 (10%)
Query: 777 KQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAK 836
+Q E E+ + +R R+R ERR R+++E + R E+ + +RER ++
Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERR----RKEKETNRNRDREKQTEIERDREREKQKG 132
Query: 837 REEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSE 896
RE E +ER + R RE +ERER+ E++R D + R DR+ E
Sbjct: 133 RERERDRGRER--------ERDRDRE---KERERQTEKDR---DGQRETETERERDRERE 178
Query: 897 GTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDR 956
+ E D + R+ EKE R R+ DR + ER R + +RE DR
Sbjct: 179 KQKERETERDRD-RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERE------TDR 231
Query: 957 VPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNW 1009
R D DRG R E DR R + + + + + + ++ + W
Sbjct: 232 RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKW 284
Score = 73.6 bits (179), Expect = 1e-12
Identities = 48/175 (27%), Positives = 83/175 (47%), Gaps = 4/175 (2%)
Query: 774 EKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE-ERERA 832
EK + + + ER + +E R R E++ R++E E+Q+ E + + RE ER+R
Sbjct: 89 EKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRD 148
Query: 833 ERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGD 892
+RE + + ++ ++ E + R+RE + E R + +R + R+ R D
Sbjct: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208
Query: 893 RDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDRE 947
R + + E D R G E + RR RD DR RD ER R+ ++R+
Sbjct: 209 RQRKTQTERQRETD---REGERETDRRRERQRDRDRGKERDRERDRKEERKKERK 260
Score = 72.4 bits (176), Expect = 3e-12
Identities = 50/141 (35%), Positives = 70/141 (49%), Gaps = 19/141 (13%)
Query: 1242 PRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRER---RDLRDDRDRRGP 1298
P D R G E SW D D DDR+RERD R+ E+ RD + DR+RR
Sbjct: 46 PLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRK 105
Query: 1299 PLRS----EREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKA 1354
+ +RE+ + R +R+ + ER+ R R+RERDRDRE+E E++
Sbjct: 106 EKETNRNRDREKQTEIERDREREKQKGRERERDR-------GRERERDRDREKERERQ-- 156
Query: 1355 SWRAEKDRESLRRTKNETDED 1375
EKDR+ R T+ E + D
Sbjct: 157 ---TEKDRDGQRETETERERD 174
Score = 72.0 bits (175), Expect = 4e-12
Identities = 63/238 (26%), Positives = 115/238 (48%), Gaps = 28/238 (11%)
Query: 717 QRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKL 776
Q KD D ++Q E + E+E+ + K R ++++ R E++
Sbjct: 67 QAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKE-------TNRNRDREKQT 119
Query: 777 KQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKERE-ERERAERA 835
+ +R E++ R ER R R+ ER R++E+E +R+ E+ +RE E ER
Sbjct: 120 EIERDREREKQKGRERERDRGRERERD----RDREKERERQTEKDRDGQRETETERERDR 175
Query: 836 KREEELREYQERVKKLEEVERKKRQRELEIE-ERERRREEER-----RLGDSSLSRKDSR 889
+RE++ ER + + K+R+R+ + E +R+R+ + ER R G+ R+ R
Sbjct: 176 EREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRER 235
Query: 890 WGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDRE 947
DRD +G E D E R KE R+ E + E + R+++++ + +D+ R+
Sbjct: 236 QRDRD------RGKERDRERDR----KEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 69.3 bits (168), Expect = 2e-11
Identities = 61/237 (25%), Positives = 118/237 (49%), Gaps = 17/237 (7%)
Query: 651 KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLI 710
+A KD D +D + + D + K ++ ++++K +ER + +++ +R K+ E
Sbjct: 67 QAHKDADGDDRQR-ERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEI---- 121
Query: 711 KSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQS 770
+R ++ + + +E ER + ER++ E K R + +DRD +
Sbjct: 122 ------ERDREREKQKGRERERDRGRERERDRDRE-KERERQTEKDRDGQRETETERERD 174
Query: 771 VYEEKLKQFE-ERLAEERHNRLEERKRQ--RKEERRITYYREKEEEEQRRAEEQMLKERE 827
EK K+ E ER + + + +ER+RQ R+ +R+ E++ E R E + + RE
Sbjct: 175 REREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRE 234
Query: 828 ERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLS 884
+ +R K + R+ +E KK + ERKK ++E + EE+ RRE+++R +S
Sbjct: 235 RQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEK--RREDKKRKWGEGIS 289
Score = 67.0 bits (162), Expect = 1e-10
Identities = 69/273 (25%), Positives = 122/273 (44%), Gaps = 55/273 (20%)
Query: 612 LRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDI----DIEDLEELDPD 667
L Q K+ + + +E +++++KT +ER K+ + K+ D E E++ D
Sbjct: 65 LGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERD 124
Query: 668 FIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQ 727
+ EK+K +ER + +E++ D +R E Q KD D +
Sbjct: 125 -------REREKQKGRERERDRGRERERDRDREKER-----------ERQTEKDRDGQRE 166
Query: 728 QEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEER 787
E ER + E++K E + DRD RQ E++ ++ +R
Sbjct: 167 TETERERDREREKQKERETE-------RDRD---------RQRDTEKERERQTDR----- 205
Query: 788 HNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQER 847
ER RQRK + E++ E R E + + RE + +R K + R+ +E
Sbjct: 206 -----ERDRQRKTQ------TERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 848 VKKLEEVERKKRQRELEIEERERRREEERRLGD 880
KK + ERKK ++E + EE+ RR +++R+ G+
Sbjct: 255 RKKERKKERKKERKEKKKEEK-RREDKKRKWGE 286
Score = 67.0 bits (162), Expect = 1e-10
Identities = 70/246 (28%), Positives = 111/246 (45%), Gaps = 32/246 (13%)
Query: 1011 HADDDRPPRRGLDEDRGSWRTADE-DRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGP 1069
H D D R+ + DR +T E DR +R DR RR E+ + RN D ++
Sbjct: 69 HKDADGDDRQR-ERDRVREKTEKERDRDRKR----DRERRR----KEKETNRNRDREKQT 119
Query: 1070 RRGLDDDRGPRRGMDD--DRGPRRGMDDDRGPRRGM--DDDRGPRRGLDDDRGPWRNADD 1125
D +R ++G + DRG R D DR R + DR +R + +R R+ +
Sbjct: 120 EIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERE--RDRER 177
Query: 1126 DRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAR 1185
++ R E DR R+ + +R R+ D +R +R + R++E R
Sbjct: 178 EKQKERETERDRDRQRDTEKER-ERQTDRERDRQRKTQTE-------------RQRETDR 223
Query: 1186 EESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDE 1245
E R R +R+ DR KERDR+ +EE K+ ++ER +ER +++ RR +
Sbjct: 224 EGERETDR--RRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Query: 1246 GGWRRG 1251
W G
Sbjct: 282 RKWGEG 287
Score = 63.9 bits (154), Expect = 1e-09
Identities = 67/254 (26%), Positives = 107/254 (42%), Gaps = 46/254 (18%)
Query: 814 EQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRRE 873
+ R+ E ++E+ E+ER KR+ E R K+ E + R+++ EIE R+R RE
Sbjct: 75 DDRQRERDRVREKTEKERDRDRKRDRERRR-----KEKETNRNRDREKQTEIE-RDRERE 128
Query: 874 EERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRD 933
+++ R +RD +G E + + R EKE R +D D +
Sbjct: 129 KQK-----------GRERERD------RGRERERDRDR---EKERERQTEKDRDGQRETE 168
Query: 934 EERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTD 993
ER R D +RE + +R DR +R E++R R D +R R T
Sbjct: 169 TERER----DREREKQKERETER--------DRDRQRDTEKER--ERQTDRERDRQRKTQ 214
Query: 994 DDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGA 1053
+R + DR R D R +R D DRG R + DR R + + ++
Sbjct: 215 TERQ----RETDREGERETDRRRERQR--DRDRGKERDRERDRKEERKKERKKERKKERK 268
Query: 1054 DDERSSWRNADDDR 1067
+ ++ R D R
Sbjct: 269 EKKKEEKRREDKKR 282
Score = 60.5 bits (145), Expect = 1e-08
Identities = 59/248 (23%), Positives = 101/248 (40%), Gaps = 33/248 (13%)
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
Q + + +R+RE +R + K + DRD + D E RR EKE
Sbjct: 67 QAHKDADGDDRQRERDR------VREKTEKERDRDRK--------RDRERRR--KEKETN 110
Query: 920 RGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSR 979
R R++ RD ER ++ G + +R D R R D ++ R E+DR +
Sbjct: 111 RNRDREKQTEIERDREREKQKGRERER------DRGRERERDRDREKERERQTEKDRDGQ 164
Query: 980 RGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPR 1039
R + + R D +R ++ + +R R D ++ R D +R R +R +
Sbjct: 165 RETETE----RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTER--Q 218
Query: 1040 RGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGP 1099
R D R G + +R R D DRG R + DR R + + ++ + +
Sbjct: 219 RETD-----REGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKE 273
Query: 1100 RRGMDDDR 1107
+ +D +
Sbjct: 274 EKRREDKK 281
Score = 59.7 bits (143), Expect = 2e-08
Identities = 57/247 (23%), Positives = 112/247 (45%), Gaps = 38/247 (15%)
Query: 676 QLEKEK-KELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERIT 734
Q E+++ +E E+ +++++K D R K E + R K ++ +E E+
Sbjct: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKE------TNRNRDREKQTEIERDREREKQK 131
Query: 735 TMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEER 794
+ ER++ E + DRD R+ E + ++ + E R +R
Sbjct: 132 GRERERDRGRERER-------DRD---------REKERERQTEKDRDGQRETETERERDR 175
Query: 795 KRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEV 854
+R++++ER R+++ + ++ E Q +ER+ R+R + +R+ E ER E
Sbjct: 176 EREKQKERETERDRDRQRDTEKERERQTDRERD-RQRKTQTERQRETDREGER----ETD 230
Query: 855 ERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPP 914
R++RQR+ + +ER RE + RK+ R +R E + + E RR
Sbjct: 231 RRRERQRDRD-RGKERDRERD---------RKEERKKERKKERKKERKEKKKEEKRREDK 280
Query: 915 EKEWRRG 921
+++W G
Sbjct: 281 KRKWGEG 287
Score = 59.3 bits (142), Expect = 2e-08
Identities = 61/270 (22%), Positives = 114/270 (42%), Gaps = 65/270 (24%)
Query: 563 KEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKE 622
++ +R R +T +ER + +R KE+ R + +K + E +R R++ K RE+E
Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
Query: 623 RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK 682
R + + +ER Q +K G + + E E++
Sbjct: 137 RDRGRERERDRDREKERERQTEKDRDGQR------------------------ETETERE 172
Query: 683 ELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREK 742
+ER K +E+ E +R +D ++E ER Q +RE+
Sbjct: 173 RDREREKQKER---------------------ETERDRDRQRDTEKERER----QTDRER 207
Query: 743 ALEHKNRMSRMLE-DRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEE 801
+ K + R E DR+ E + + ER + + +R+R RKEE
Sbjct: 208 DRQRKTQTERQRETDRE-------------GERETDRRRERQRDRDRGKERDRERDRKEE 254
Query: 802 RRITYYREKEEEEQRRAEEQMLKEREERER 831
R+ R+KE +++R+ +++ K RE+++R
Sbjct: 255 RK--KERKKERKKERKEKKKEEKRREDKKR 282
Score = 53.1 bits (126), Expect = 2e-06
Identities = 58/245 (23%), Positives = 102/245 (41%), Gaps = 62/245 (25%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKE 618
++ +++ +R ++T R +R + I+R++E +Q+ E ++ R E ER R KE
Sbjct: 94 RDRKRDRERRRKEKETNRNR-DREKQTEIERDREREKQKGRERERDRGRERERDRDREKE 152
Query: 619 REKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLE 678
RE++ Q + +T RER + +K Q E
Sbjct: 153 RERQTEKDRDGQRETETERERDREREK------------------------------QKE 182
Query: 679 KEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQL 738
+E + ++R ++ EK ER ++ + R +D Q E +R T +
Sbjct: 183 RETERDRDRQRDTEK-----ERERQTD------------RERDRQRKTQTERQRETDREG 225
Query: 739 EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQR 798
ERE +R DRD R + + + EER E + R +ERK ++
Sbjct: 226 ERE-----TDRRRERQRDRD---------RGKERDRERDRKEERKKERKKERKKERKEKK 271
Query: 799 KEERR 803
KEE+R
Sbjct: 272 KEEKR 276
Score = 48.5 bits (114), Expect = 4e-05
Identities = 42/174 (24%), Positives = 80/174 (45%), Gaps = 21/174 (12%)
Query: 538 KPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQR 597
K I +++E + Q K +E R R + + KER Q EK+ QR
Sbjct: 117 KQTEIERDREREKQ-------KGRERERDRGRERERDRDREKERER----QTEKDRDGQR 165
Query: 598 EAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIK-----KTELGAKA 652
E E ++ R E E+ ++ ER+++R ++ +++T RER Q K + E +
Sbjct: 166 ETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG 225
Query: 653 FKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEE 706
++ D + D D + ++ ++E+ +ER K ++K+ + K+ EE
Sbjct: 226 ERETDRRRERQRDRD-----RGKERDRERDRKEERKKERKKERKKERKEKKKEE 274
Score = 42.4 bits (98), Expect = 0.003
Identities = 43/201 (21%), Positives = 87/201 (43%), Gaps = 33/201 (16%)
Query: 559 KNSRKEHQRILARRQTIEERK--ERLESLNIQREKEELEQREAELQKVRKAEEERLRQEA 616
+N +E Q + R + E++K ER +RE++ ++E E Q + + +R +
Sbjct: 111 RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE 170
Query: 617 KEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQ 676
+ER++ER Q+ + ++ R+R D E E D +
Sbjct: 171 RERDREREKQKERETERDRDRQR-----------------DTEKERERQTD-------RE 206
Query: 677 LEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTM 736
++++K ER + +++ + E +R E + R K+ D ++EER
Sbjct: 207 RDRQRKTQTERQRETDREGER-ETDRRRER------QRDRDRGKERDRERDRKEERKKER 259
Query: 737 QLEREKALEHKNRMSRMLEDR 757
+ ER+K + K + + ED+
Sbjct: 260 KKERKKERKEKKKEEKRREDK 280
Score = 40.0 bits (92), Expect = 0.016
Identities = 25/93 (26%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Query: 559 KNSRKEHQRILARRQTIEERK--ERLESLNIQREKEELEQREAELQKVRKAEEERLRQEA 616
+++ KE +R R + + + ER + + E+E +RE + + R E +R R
Sbjct: 193 RDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
Query: 617 KEREKERILQEHEQIKKKTVRERLEQIKKTELG 649
+ER+KER + ++ K+K E+ + KK + G
Sbjct: 253 EERKKERKKERKKERKEKKKEEKRREDKKRKWG 285
Score = 32.3 bits (72), Expect = 3.2
Identities = 20/90 (22%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 545 EKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKV 604
EKE + Q T ++ +++ Q R E +E QR+++ ++R+ E +
Sbjct: 196 EKERERQ---TDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRK 252
Query: 605 RKAEEERLRQEAKEREKERILQEHEQIKKK 634
+ ++ER ++ KER++++ ++ + KK+
Sbjct: 253 EERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 30.8 bits (68), Expect = 9.4
Identities = 24/87 (27%), Positives = 45/87 (51%), Gaps = 9/87 (10%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
+E++ Q + T + + +E +R RR+ E +++R RE++ E+R+ E +K
Sbjct: 205 RERDRQRKTQ-TERQRETDREGERETDRRR--ERQRDRDRGKERDRERDRKEERKKERKK 261
Query: 604 VRKAE------EERLRQEAKEREKERI 624
RK E EE+ R++ K + E I
Sbjct: 262 ERKKERKEKKKEEKRREDKKRKWGEGI 288
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 94.7 bits (234), Expect = 5e-19
Identities = 132/567 (23%), Positives = 245/567 (43%), Gaps = 78/567 (13%)
Query: 543 LQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQ 602
L+ ++E A L + Q A +T E ++E+ ES ++E+ E+E+ E +
Sbjct: 115 LERQKEFDPTITDASLSLPSRRMQNDTAENETTE-KEEKSES---RQERYEIEETETVTK 170
Query: 603 KVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLE 662
+K + R +E K+ +KE+ +E E+ K+ ++ E ++ E ++ ++ + L+
Sbjct: 171 SYQK-NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLK 229
Query: 663 ELDPDFIMAKQVEQLEKEKKELQ--ERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIK 720
KQ E+ E+ E+ E+++ ++K+ ERA RLE A E +RIK
Sbjct: 230 NGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERA-RLE-------AEERERIK 281
Query: 721 DMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFE 780
EQ ++ ++E E+ + R R E+R E++++ E
Sbjct: 282 A----EQDKKIADERARIEAEEKAAAQERERREAEER----------------ERMREEE 321
Query: 781 ERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEE 840
+R AEER EE KR +E +RI ++ EE++R +E+ + EER+RA + E+
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381
Query: 841 LREYQERVKKLEEVERKKRQRELEIEERERRRE---------EERRLGDSSLSRKDSRWG 891
E Q+R K+LEE + ++ +++ E+ E++ E +E +L + L ++ G
Sbjct: 382 KVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKG 441
Query: 892 DR---------DSEGTWRKGPEADSEWRRGPPEKE-----WRRGEGRDEDRSHRRDEERP 937
+ + + T++K D + ++ KE R +G E +S + E
Sbjct: 442 TKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKS-QNGEFMT 500
Query: 938 RRLGDDED--REPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDD 995
+L E+ P R D G +R E R RRG + +
Sbjct: 501 HKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRR--RRGETESEEFEKLKQKQ 558
Query: 996 RPPRRIADE---DRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGG 1052
+ +E R R ++ RR +E R +E +R + ++ RR
Sbjct: 559 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEE----KRRLKEEIERRRAE 614
Query: 1053 ADDERSSWRNADDDRGPRRGLDDDRGP 1079
A ++R + P GL DD+ P
Sbjct: 615 AAEKR--------QKMPEDGLSDDKKP 633
Score = 88.2 bits (217), Expect = 5e-17
Identities = 90/430 (20%), Positives = 188/430 (43%), Gaps = 62/430 (14%)
Query: 575 IEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKK 634
+++ + R E +RE+ LE Q+ EEE R+ + +ER+ Q+ E+
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 635 TVRERLEQIKKTELGAKAFKDIDIE-DLEELDPDFIMAKQVEQLEKEKKELQERLKNQ-- 691
V +++E + + + K +E D + + + E+ +K LQE L+ Q
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Query: 692 -----------------------------EKKIDYFERAKRLEEIPLIKSAYEEQRIKDM 722
E+K + + +EE + +Y++ +D
Sbjct: 121 FDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 180
Query: 723 DLWEQQEEERITTMQLEREKALEHKNRMSRMLEDR------DLFVMRLKAARQSVYEEKL 776
+ +++++E+ + + ++ +N++ M+E++ + VM LK + S E K
Sbjct: 181 EENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQ 240
Query: 777 KQFEERLAEE--RHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAE- 833
++ E+ ++E H ++EE ++R E R R + EE +R EQ K +ER R E
Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAEAERA---RLEAEERERIKAEQDKKIADERARIEA 297
Query: 834 ---RAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRW 890
A +E E RE +ER + EE +R +R+ EE +R EE +R+ + + R
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 357
Query: 891 GDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSL 950
++ E +R E++ R E +E+++ +++R ++L + +
Sbjct: 358 RIKEEE-------------KRAAEERQRARAE--EEEKAKVEEQKRNKQLEEKKHAMQET 402
Query: 951 RPDDDRVPRR 960
+ ++V ++
Sbjct: 403 KIKGEKVEQK 412
Score = 66.6 bits (161), Expect = 2e-10
Identities = 121/662 (18%), Positives = 270/662 (40%), Gaps = 97/662 (14%)
Query: 776 LKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQ------RRAEEQMLKEREER 829
+ FE R R R ++R+ R E RI Y R ++EE+ RRA ++ L++++E
Sbjct: 1 MDDFERR----RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEE 56
Query: 830 E-----------RAERAKREEELR--------EYQERVKKLEEVERKKRQRELEIEER-E 869
E A+ + +EE + E + LE + R++ +R+ ++E E
Sbjct: 57 ESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALE 116
Query: 870 RRREEERRLGDSSLSRKDSRWGDRDSEG-TWRKGPEADSEWRRGPPE------KEWRRGE 922
R++E + + D+SLS R + +E T K +++S R E K +++ +
Sbjct: 117 RQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKND 176
Query: 923 GRDEDRSHRRD-------EERPRRLGDDEDR-----EPSLRPDDDRVPRRGMDDDRGPRR 970
RD + + + D EE+P+R E++ E + + + +
Sbjct: 177 WRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSE 236
Query: 971 GPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWR 1030
P+++ +G+D+ + ++D+ A+ +R + +R ++D+ +
Sbjct: 237 EPKQEEEREQGSDEISHHEKMEEEDKER---AEAERARLEAEERERIKA---EQDK---K 287
Query: 1031 TADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPR 1090
ADE R ++ + + + ER + R + ++R R ++ R
Sbjct: 288 IADE----RARIEAEE--KAAAQERERREAEERERMREEEKRAAEER-QRIKEEEKRAAE 340
Query: 1091 RGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSR 1150
+R ++ R+ + ++ + A ++R R E+++ +++ + ++
Sbjct: 341 ERQRIKEEEKRAAEE----RQRIKEEE---KRAAEERQRARAEEEEKA---KVEEQKRNK 390
Query: 1151 RADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERD 1210
+ ++ + + + ++ G W ++KA+E+ + EE+ + +R+
Sbjct: 391 QLEEKKHAMQETKIKGEKVEQKIE-GKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKRE 449
Query: 1211 RDNQD----REENDKDPERERDRERD------VDREDRFRRPRDEGGWRRGPAEESSSWR 1260
+ +D ++E KD + ++D+E +DR+ F + + G +
Sbjct: 450 KLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNG--EFMTHKLKHTE 507
Query: 1261 DSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR 1320
++ R +E + + + L + R RRG +E EE ++
Sbjct: 508 NTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRG---ETESEEFEKLKQKQQEAALE 564
Query: 1321 VEE----RDPPRRVPPPALSRDRERDRDRE--REGEKEKASWRAEKDRESLRRTKNETDE 1374
+EE R+ R+V R ++ + DR+ E EK + E+ R + + E
Sbjct: 565 LEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Query: 1375 DG 1376
DG
Sbjct: 625 DG 626
Score = 57.4 bits (137), Expect = 9e-08
Identities = 112/578 (19%), Positives = 227/578 (39%), Gaps = 114/578 (19%)
Query: 828 ERERAERAKREEELR------EYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDS 881
ER R R ++ EE+R YQ EE R++R+R + ER R+++EE LG
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQ--ERLRQKQEEESLGQV 62
Query: 882 SLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDE----DRSHRRDEERP 937
+ D+ P+ +++ + E G DE +R RR+E R
Sbjct: 63 T---------DQVEVNAQNSVPDEEAKTTTTNTQVE-----GDDEAAFLERLARREERRQ 108
Query: 938 RRLGDDEDRE----PSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTD 993
+RL + +R+ P++ +P R M +D E++ S + +R T+
Sbjct: 109 KRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSE--SRQERYEIEETE 166
Query: 994 DDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGA 1053
+ + +WR A++++ + +E+ E+ P+RG G +
Sbjct: 167 TVTKSYQ-----KNDWRDAEENKKEDKEKEEE--------EEEKPKRG---SIGENQVEV 210
Query: 1054 DDERSSWRNADDD--RGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRR 1111
E + + ++ + G P++ + ++G D+ M+++
Sbjct: 211 MVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQG-----SDEISHHEKMEEE----- 260
Query: 1112 GLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRP 1171
D +R AE +R + +R+ +A+ D+
Sbjct: 261 ------------DKER-----AEAERARLEAEERERI--KAEQDK--------------- 286
Query: 1172 LVKPGGWREKEKAREESWGPPRESRPSEEREWDREKER--DRDNQDREENDKDPERERDR 1229
K R + +A E++ RE R +EERE RE+E+ + Q +E +K ER R
Sbjct: 287 --KIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQR 344
Query: 1230 ERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDL 1289
++ ++ R R + +R E + + + + R ++ ++++ + +
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI 404
Query: 1290 RDDRDRRGPPLRSEREEVSSWRRADDRKDDRV-----EERDPPRRVPPPALSRDRERDRD 1344
+ ++ + + E + V+ + +D+ V EE+ + L D+ +
Sbjct: 405 KGEKVEQ----KIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKK 460
Query: 1345 REREGEKEKASWRAEKDRESLRRTKNETD-EDGWTTVR 1381
E + EK K KD+E K+ D + G+T V+
Sbjct: 461 EEIKDEKIK------KDKEPKEEVKSFMDRKKGFTEVK 492
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 94.4 bits (233), Expect = 7e-19
Identities = 94/387 (24%), Positives = 185/387 (47%), Gaps = 30/387 (7%)
Query: 509 PHLQSMPSEQIRNQLTAMSSVLAKA------LEVIKPAHILQEKEEQHQLAVTAYLKNSR 562
P Q M E+ + +L KA +E+ K L E++++ K
Sbjct: 345 PSYQKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEW 404
Query: 563 KEHQRILARRQ-----TIEERKERLESLNIQREKE---ELEQREA---ELQKVRKAEEER 611
+ QR L ++ +E+R E+ L QRE+E ++E+REA EL++ R+ E ER
Sbjct: 405 ERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWER 464
Query: 612 LRQEA----KEREKERILQEHEQIKKKTVRERLEQIK-KTELGAKAFKDIDIEDLEELDP 666
+R++ K RE+E I++ + KKK + LE + K + + +D+ ++ +
Sbjct: 465 IRRQELLNQKNREQEEIVRLNS--KKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTE 522
Query: 667 DFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWE 726
++ KQ + E K+LQ+ L+ + K+ Y K+L + + + L
Sbjct: 523 LEVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLH 582
Query: 727 QQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEE 786
++ E+ Q +E+ + + L + D F +LK R++ ++L E+L +
Sbjct: 583 KKSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLAL--EQLYKI 640
Query: 787 RHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKE---REERERAERAKREEELRE 843
+ ++L+E +R+R E + ++ + ++ +E + KE +EE E+ +R + E+ +
Sbjct: 641 KRDKLKEIERKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEK 700
Query: 844 YQERVKKLEEVERKKRQRELEIEERER 870
QE +K EE +RK + L+ EE++R
Sbjct: 701 IQEEERKAEEKQRKDKD-TLKAEEKKR 726
Score = 87.0 bits (214), Expect = 1e-16
Identities = 94/339 (27%), Positives = 161/339 (47%), Gaps = 36/339 (10%)
Query: 543 LQEKEEQHQLAVTAYLKNSRK-EHQRILARRQTIEERKERLESLNIQREKE-ELEQREAE 600
LQE+E + QL + L+ R+ E QR RR+ IE R+ + L QR E E +R+
Sbjct: 411 LQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQEL 470
Query: 601 LQKVRKAEEERLRQEAKER----EKERILQEHEQIKKKTVRERLE-QIKKTELGAKAFK- 654
L + + +EE +R +K++ E E + +H+QI + RL+ Q +KTEL +
Sbjct: 471 LNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQC 530
Query: 655 DIDIEDLEELDPDFI-MAKQVEQLEKEKKELQERLKNQE--------------KKIDYFE 699
D++I ++++L + ++ L EK+ L ER+KN + K ++ E
Sbjct: 531 DLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEE 590
Query: 700 RAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEE---RITTMQLEREKALEHKNRMSRMLED 756
+RL+E ++ +MD + Q +E T QL E+ + K + +E
Sbjct: 591 LCQRLKEQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIER 650
Query: 757 RDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQR----KEERRITYYREKEE 812
+ L +M+ K K KQ +E L +E + EE K++R K + +I K E
Sbjct: 651 KRLELMQKKKLEDEA-ARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAE 709
Query: 813 EEQRRAEEQMLKEREERERAE-----RAKREEELREYQE 846
E+QR+ ++ + E ++RE A RA E R + E
Sbjct: 710 EKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDE 748
Score = 68.2 bits (165), Expect = 5e-11
Identities = 84/383 (21%), Positives = 176/383 (45%), Gaps = 76/383 (19%)
Query: 582 LESLNIQREKEELEQREAELQKVRKAEEER------------LRQEAKERE--------- 620
L S +E+E ++ + RKA ER + Q+ +E E
Sbjct: 344 LPSYQKMQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEE 403
Query: 621 ---KERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQL 677
K+R LQE E K+ + +RLE+ ++ E + + DIE E + +++E
Sbjct: 404 WERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWE 463
Query: 678 EKEKKE-LQERLKNQEKKIDYFERAKRLE-EIPLIKSAYEE--QRIKDMDLWEQQEEERI 733
++E L ++ + QE+ + + K L E+ + +++ R++D+ L +Q ++ +
Sbjct: 464 RIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTEL 523
Query: 734 TTMQLE-----------REKALEHKNRMSRMLEDRDLFVMRLK--------------AAR 768
+ + +++ E++N++ ++ ++ L R+K +
Sbjct: 524 EVLDKQCDLEIMEIKQLQQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHK 583
Query: 769 QSVYEE----KLKQFEERLAEERHNRLEERK--RQRKEERRITY-------------YRE 809
+S+ +E +LK+ + L +E ++L E + +E R TY R+
Sbjct: 584 KSLEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLYKIKRD 643
Query: 810 KEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQREL---EIE 866
K +E +R+ E M K++ E E A +AK+ +E ++E ++K EE ++K+ Q E +I+
Sbjct: 644 KLKEIERKRLELMQKKKLEDEAARKAKQGKE-NLWKENLRKEEEEKQKRLQEEKTQEKIQ 702
Query: 867 ERERRREEERRLGDSSLSRKDSR 889
E ER+ EE++R +L ++ +
Sbjct: 703 EEERKAEEKQRKDKDTLKAEEKK 725
Score = 53.1 bits (126), Expect = 2e-06
Identities = 53/236 (22%), Positives = 108/236 (45%), Gaps = 29/236 (12%)
Query: 667 DFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWE 726
+FI+A + + K + L L E F K+++ I +Y++ + E
Sbjct: 301 EFILAMHLTDMAKAGQPLPLTLP-PELVPPSFRGGKQIDSINGTLPSYQKMQ-------E 352
Query: 727 QQEEERITTMQLEREKA------LEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFE 780
++ ++++ ++ KA +E + R ++E + R + +E K ++ +
Sbjct: 353 EEPQKKLPVTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQ 412
Query: 781 ERL------AEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834
E+ E+R + E +RQR+EERR ++ E+R A +Q L ER+ R ER
Sbjct: 413 EQEWKKQLELEKRLEKQRELERQREEERR-------KDIERREAAKQEL-ERQRRLEWER 464
Query: 835 AKREEELREYQERVKKLEEVERKKRQRELEIEERERRREE-ERRLGDSSLSRKDSR 889
+R+E L + +++ + KK+ LE+E + ++ RL D L ++ +
Sbjct: 465 IRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQK 520
Score = 37.4 bits (85), Expect = 0.10
Identities = 23/73 (31%), Positives = 39/73 (53%), Gaps = 11/73 (15%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDR--------EKERDRDNQDREENDKDPERERDRE 1230
R+ +K +EE W R+ R +E+EW + EK+R+ + Q EE KD ER +
Sbjct: 395 RKAQKEKEE-W--ERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAK 451
Query: 1231 RDVDREDRFRRPR 1243
++++R+ R R
Sbjct: 452 QELERQRRLEWER 464
Score = 32.0 bits (71), Expect = 4.2
Identities = 35/179 (19%), Positives = 79/179 (44%), Gaps = 9/179 (5%)
Query: 1188 SWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGG 1247
S+ +E P ++ E +R + N +R + + R+ E+ RE + +++
Sbjct: 346 SYQKMQEEEPQKKLPVTFEDKR-KANYERGNMELEKRRQALMEQQ-QREAERKAQKEKEE 403
Query: 1248 WRRGPAE-ESSSWR---DSSRRDDRDRDDRRRERDDRRDLRERRDLRD---DRDRRGPPL 1300
W R E + W+ + +R ++ R+ R+ ++RR ERR+ +R RR
Sbjct: 404 WERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWE 463
Query: 1301 RSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAE 1359
R R+E+ + + + + R+ + + AL+ ++ R ++ +K + + E
Sbjct: 464 RIRRQELLNQKNREQEEIVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTE 522
Score = 32.0 bits (71), Expect = 4.2
Identities = 13/55 (23%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Query: 1178 WREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERD 1232
W+E + EE ++ R EE+ ++ +E +R ++++ DKD + +++R+
Sbjct: 677 WKENLRKEEEE----KQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRE 727
Score = 31.2 bits (69), Expect = 7.2
Identities = 23/111 (20%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDRDNQD---REENDKDPERERDRERDVDR 1235
+ ++ E+ E+ EW+R K+R+ Q+ + E +K E++R+ ER +
Sbjct: 380 KRRQALMEQQQREAERKAQKEKEEWER-KQRELQEQEWKKQLELEKRLEKQRELERQREE 438
Query: 1236 EDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRER 1286
E R R E + + W R++ ++ +R +E R + +++
Sbjct: 439 ERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLNSKKK 489
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 92.0 bits (227), Expect = 3e-18
Identities = 100/396 (25%), Positives = 184/396 (46%), Gaps = 52/396 (13%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKE--EQHQLAVTAYLKNSRKEHQRILARRQT 574
E++R + +LA+ LE ++ + LQE+ EQH LK++++E ++++A +
Sbjct: 85 EKLRQLMQEEQDLLARELEELRLSMNLQERRIREQH-----GKLKSAKEEQRKLIAEQLL 139
Query: 575 IEERKERLESLNIQREKE-ELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKK 633
E K+ L RE E +L Q+ + EE++ ++ E+E +R E+E+ ++
Sbjct: 140 YEHWKKNNPKL---REMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARR 196
Query: 634 KTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMA----KQVEQLEKEKKELQERLK 689
+ + + ++ +L K + ++ +EEL + A K+ E L K++ EL ERL+
Sbjct: 197 EALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWEL-ERLE 255
Query: 690 NQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNR 749
+ K+++ F + L ++ Y Q + QQ +E + + + LE ++
Sbjct: 256 EERKQMEAFRQKAELGRF--LRHQYNAQ----LSRRTQQIQEELEADRRILQALLEKEDE 309
Query: 750 MSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYRE 809
R+ R VM A + EE+L Q E E L E ++ E+R + RE
Sbjct: 310 SQRLHLARREQVMADVAWMKQAIEEQL-QLERAREAELQMLLREEAKEMWEKREAEWARE 368
Query: 810 KEE--------------------EEQRRAEEQMLKEREE-----RERAERAKREEELREY 844
+ E+ RRA+E+ LK RE+ E E A+RE+E E
Sbjct: 369 RSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEK 428
Query: 845 QERVKKLEEVERKKRQREL---EIEERERRREEERR 877
+ +K +E+E + +R L E +++E EEE R
Sbjct: 429 LKSARK-QELEAQVAERRLQAWEADQQEEEEEEEAR 463
Score = 80.5 bits (197), Expect = 1e-14
Identities = 121/487 (24%), Positives = 221/487 (45%), Gaps = 89/487 (18%)
Query: 417 QPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAAR 476
Q E+E L+Q Q N+ R+ S + E+S TS + A+Q E+ + R
Sbjct: 23 QREQEARLRQQWEQ--NSRYFRMSDICSS--KQAEWSSKTSYQRSMHAYQREKMKEEKRR 78
Query: 477 HCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQS-------------------MPSE 517
L+ R + + + DL E+ + +LQ + +E
Sbjct: 79 --SLEARREKLRQLMQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAE 136
Query: 518 QIRNQLTAMSSVLAKALEV-IKPAHILQ----EKEEQHQLAVTAYLKNSRKEHQRILARR 572
Q+ + ++ + +E+ + H++ +KEE+ Q TA +N R E++ ARR
Sbjct: 137 QLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARR 196
Query: 573 QTIEERK---------ERLESLNIQREKEELEQREAELQKVRKAEE---------ERLRQ 614
+ +E K ++L++ + ++ EEL+ +E E K++K +E ERL +
Sbjct: 197 EALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEE 256
Query: 615 EAKEREKERILQE---------HEQIKKKT--VRERLEQIKKTELGAKAFKDIDIEDL-- 661
E K+ E R E + Q+ ++T ++E LE ++ L A K+ + + L
Sbjct: 257 ERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRI-LQALLEKEDESQRLHL 315
Query: 662 ---EELDPDFIMAKQV--EQLEKEKK---ELQERLKNQEKKIDYFERAKRLEEIPLIKSA 713
E++ D KQ EQL+ E+ ELQ L+ + K++ KR E +SA
Sbjct: 316 ARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEM----WEKREAEWARERSA 371
Query: 714 YEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYE 773
+ + + +QQ +E+I + +E++L+H+ ++ R LE+ +R A R+
Sbjct: 372 RDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEE-----VRELARREKEES 426
Query: 774 EKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQM---LKEREERE 830
EKLK + +E ++ ER+ Q E + +E+EEEE+ R EQ+ L ++E
Sbjct: 427 EKLKSARK---QELEAQVAERRLQAWEADQ----QEEEEEEEARRVEQLSDALLQQEAET 479
Query: 831 RAERAKR 837
AE+ R
Sbjct: 480 MAEQGYR 486
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/286 (25%), Positives = 126/286 (44%), Gaps = 56/286 (19%)
Query: 609 EERLRQE-AKEREKE-RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDP 666
++RL Q+ A++RE+E R+ Q+ EQ + + K+ E +K
Sbjct: 13 QQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKT-------------- 58
Query: 667 DFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWE 726
+ + Q EK K+E + L+ + +K+ R EE L+ EE R+ M+L E
Sbjct: 59 SYQRSMHAYQREKMKEEKRRSLEARREKL----RQLMQEEQDLLARELEELRLS-MNLQE 113
Query: 727 QQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEE 786
++ E +H S E R L +L KL++ E L ++
Sbjct: 114 RRIRE-------------QHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQK 160
Query: 787 RHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846
E +++ K+++ T E+E +R E + ER RE ER K EEE R+ ++
Sbjct: 161 HVVNSWEMQKEEKKQQEAT-----AEQENKRYENEY--ERARREALERMKAEEERRQLED 213
Query: 847 RVK-----------KLEEVERKKRQRELEIEERER----RREEERR 877
+++ KL+EVE K ++E E ++R R EEER+
Sbjct: 214 KLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERK 259
Score = 56.2 bits (134), Expect = 2e-07
Identities = 71/319 (22%), Positives = 144/319 (45%), Gaps = 50/319 (15%)
Query: 596 QREAELQKVRKAEEE-RLRQEAKE-----REKERILQEHEQIKKKTV---------RERL 640
Q+ Q R+ E+E RLRQ+ ++ R + + + KT RE++
Sbjct: 13 QQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKM 72
Query: 641 EQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFER 700
++ K+ L A+ K + L + + D ++A+++E+L + R++ Q K+ +
Sbjct: 73 KEEKRRSLEARREK---LRQLMQEEQD-LLARELEELRLSMNLQERRIREQHGKLKSAKE 128
Query: 701 AKR---LEEIPLIKSAYEEQRIKDMDL----------WEQQEEERITTMQLEREKALEHK 747
+R E++ ++++M+L WE Q+EE+ ++E E +
Sbjct: 129 EQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEK-----KQQEATAEQE 183
Query: 748 NRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERL-AEERHNRLEERK-------RQRK 799
N+ +R R +A + EE+ +Q E++L AE ++EE K + +K
Sbjct: 184 NKRYENEYER----ARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKK 239
Query: 800 EERRITYYR-EKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKK 858
E+ + R E E E+ R + + +++ E R R + +L +++++ E +R+
Sbjct: 240 EQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRI 299
Query: 859 RQRELEIEERERRREEERR 877
Q LE E+ +R RR
Sbjct: 300 LQALLEKEDESQRLHLARR 318
Score = 46.2 bits (108), Expect = 2e-04
Identities = 53/247 (21%), Positives = 102/247 (41%), Gaps = 29/247 (11%)
Query: 707 IPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKA 766
+P + S + Q+ + L Q+E+E Q E+ +R RM +
Sbjct: 3 LPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQN------SRYFRMSD----------- 45
Query: 767 ARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
+ K ++ + + +R +R++ ++E+RR R ++ + + E+ +L
Sbjct: 46 ----ICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQLMQEEQDLLARE 101
Query: 827 EERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRK 886
E R +E +RE ++K +E +RK +L E ++ + R + + L +K
Sbjct: 102 LEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREM-ELDLHQK 160
Query: 887 D--SRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDE 944
+ W + E +K EA +E E E+ R R E + EE R+L D
Sbjct: 161 HVVNSWEMQKEE---KKQQEATAEQENKRYENEYER--ARREALERMKAEEERRQLEDKL 215
Query: 945 DREPSLR 951
E L+
Sbjct: 216 QAEALLQ 222
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 92.0 bits (227), Expect = 3e-18
Identities = 100/396 (25%), Positives = 184/396 (46%), Gaps = 52/396 (13%)
Query: 517 EQIRNQLTAMSSVLAKALEVIKPAHILQEKE--EQHQLAVTAYLKNSRKEHQRILARRQT 574
E++R + +LA+ LE ++ + LQE+ EQH LK++++E ++++A +
Sbjct: 85 EKLRQLMQEEQDLLARELEELRLSMNLQERRIREQH-----GKLKSAKEEQRKLIAEQLL 139
Query: 575 IEERKERLESLNIQREKE-ELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKK 633
E K+ L RE E +L Q+ + EE++ ++ E+E +R E+E+ ++
Sbjct: 140 YEHWKKNNPKL---REMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARR 196
Query: 634 KTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMA----KQVEQLEKEKKELQERLK 689
+ + + ++ +L K + ++ +EEL + A K+ E L K++ EL ERL+
Sbjct: 197 EALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWEL-ERLE 255
Query: 690 NQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNR 749
+ K+++ F + L ++ Y Q + QQ +E + + + LE ++
Sbjct: 256 EERKQMEAFRQKAELGRF--LRHQYNAQ----LSRRTQQIQEELEADRRILQALLEKEDE 309
Query: 750 MSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYRE 809
R+ R VM A + EE+L Q E E L E ++ E+R + RE
Sbjct: 310 SQRLHLARREQVMADVAWMKQAIEEQL-QLERAREAELQMLLREEAKEMWEKREAEWARE 368
Query: 810 KEE--------------------EEQRRAEEQMLKEREE-----RERAERAKREEELREY 844
+ E+ RRA+E+ LK RE+ E E A+RE+E E
Sbjct: 369 RSARDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEEVRELARREKEESEK 428
Query: 845 QERVKKLEEVERKKRQREL---EIEERERRREEERR 877
+ +K +E+E + +R L E +++E EEE R
Sbjct: 429 LKSARK-QELEAQVAERRLQAWEADQQEEEEEEEAR 463
Score = 80.5 bits (197), Expect = 1e-14
Identities = 121/487 (24%), Positives = 221/487 (45%), Gaps = 89/487 (18%)
Query: 417 QPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAAR 476
Q E+E L+Q Q N+ R+ S + E+S TS + A+Q E+ + R
Sbjct: 23 QREQEARLRQQWEQ--NSRYFRMSDICSS--KQAEWSSKTSYQRSMHAYQREKMKEEKRR 78
Query: 477 HCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQS-------------------MPSE 517
L+ R + + + DL E+ + +LQ + +E
Sbjct: 79 --SLEARREKLRQLMQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAE 136
Query: 518 QIRNQLTAMSSVLAKALEV-IKPAHILQ----EKEEQHQLAVTAYLKNSRKEHQRILARR 572
Q+ + ++ + +E+ + H++ +KEE+ Q TA +N R E++ ARR
Sbjct: 137 QLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARR 196
Query: 573 QTIEERK---------ERLESLNIQREKEELEQREAELQKVRKAEE---------ERLRQ 614
+ +E K ++L++ + ++ EEL+ +E E K++K +E ERL +
Sbjct: 197 EALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEE 256
Query: 615 EAKEREKERILQE---------HEQIKKKT--VRERLEQIKKTELGAKAFKDIDIEDL-- 661
E K+ E R E + Q+ ++T ++E LE ++ L A K+ + + L
Sbjct: 257 ERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRI-LQALLEKEDESQRLHL 315
Query: 662 ---EELDPDFIMAKQV--EQLEKEKK---ELQERLKNQEKKIDYFERAKRLEEIPLIKSA 713
E++ D KQ EQL+ E+ ELQ L+ + K++ KR E +SA
Sbjct: 316 ARREQVMADVAWMKQAIEEQLQLERAREAELQMLLREEAKEM----WEKREAEWARERSA 371
Query: 714 YEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYE 773
+ + + +QQ +E+I + +E++L+H+ ++ R LE+ +R A R+
Sbjct: 372 RDRLMSEVLTGRQQQIQEKIEQNRRAQEESLKHREQLIRNLEE-----VRELARREKEES 426
Query: 774 EKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQM---LKEREERE 830
EKLK + +E ++ ER+ Q E + +E+EEEE+ R EQ+ L ++E
Sbjct: 427 EKLKSARK---QELEAQVAERRLQAWEADQ----QEEEEEEEARRVEQLSDALLQQEAET 479
Query: 831 RAERAKR 837
AE+ R
Sbjct: 480 MAEQGYR 486
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/286 (25%), Positives = 126/286 (44%), Gaps = 56/286 (19%)
Query: 609 EERLRQE-AKEREKE-RILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDP 666
++RL Q+ A++RE+E R+ Q+ EQ + + K+ E +K
Sbjct: 13 QQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKT-------------- 58
Query: 667 DFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWE 726
+ + Q EK K+E + L+ + +K+ R EE L+ EE R+ M+L E
Sbjct: 59 SYQRSMHAYQREKMKEEKRRSLEARREKL----RQLMQEEQDLLARELEELRLS-MNLQE 113
Query: 727 QQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEE 786
++ E +H S E R L +L KL++ E L ++
Sbjct: 114 RRIRE-------------QHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQK 160
Query: 787 RHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846
E +++ K+++ T E+E +R E + ER RE ER K EEE R+ ++
Sbjct: 161 HVVNSWEMQKEEKKQQEAT-----AEQENKRYENEY--ERARREALERMKAEEERRQLED 213
Query: 847 RVK-----------KLEEVERKKRQRELEIEERER----RREEERR 877
+++ KL+EVE K ++E E ++R R EEER+
Sbjct: 214 KLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERK 259
Score = 56.2 bits (134), Expect = 2e-07
Identities = 71/319 (22%), Positives = 144/319 (45%), Gaps = 50/319 (15%)
Query: 596 QREAELQKVRKAEEE-RLRQEAKE-----REKERILQEHEQIKKKTV---------RERL 640
Q+ Q R+ E+E RLRQ+ ++ R + + + KT RE++
Sbjct: 13 QQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKM 72
Query: 641 EQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFER 700
++ K+ L A+ K + L + + D ++A+++E+L + R++ Q K+ +
Sbjct: 73 KEEKRRSLEARREK---LRQLMQEEQD-LLARELEELRLSMNLQERRIREQHGKLKSAKE 128
Query: 701 AKR---LEEIPLIKSAYEEQRIKDMDL----------WEQQEEERITTMQLEREKALEHK 747
+R E++ ++++M+L WE Q+EE+ ++E E +
Sbjct: 129 EQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEK-----KQQEATAEQE 183
Query: 748 NRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERL-AEERHNRLEERK-------RQRK 799
N+ +R R +A + EE+ +Q E++L AE ++EE K + +K
Sbjct: 184 NKRYENEYER----ARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKK 239
Query: 800 EERRITYYR-EKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKK 858
E+ + R E E E+ R + + +++ E R R + +L +++++ E +R+
Sbjct: 240 EQENLLKQRWELERLEEERKQMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEELEADRRI 299
Query: 859 RQRELEIEERERRREEERR 877
Q LE E+ +R RR
Sbjct: 300 LQALLEKEDESQRLHLARR 318
Score = 46.2 bits (108), Expect = 2e-04
Identities = 53/247 (21%), Positives = 102/247 (41%), Gaps = 29/247 (11%)
Query: 707 IPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKA 766
+P + S + Q+ + L Q+E+E Q E+ +R RM +
Sbjct: 3 LPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQN------SRYFRMSD----------- 45
Query: 767 ARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
+ K ++ + + +R +R++ ++E+RR R ++ + + E+ +L
Sbjct: 46 ----ICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQLMQEEQDLLARE 101
Query: 827 EERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRK 886
E R +E +RE ++K +E +RK +L E ++ + R + + L +K
Sbjct: 102 LEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREM-ELDLHQK 160
Query: 887 D--SRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDE 944
+ W + E +K EA +E E E+ R R E + EE R+L D
Sbjct: 161 HVVNSWEMQKEE---KKQQEATAEQENKRYENEYER--ARREALERMKAEEERRQLEDKL 215
Query: 945 DREPSLR 951
E L+
Sbjct: 216 QAEALLQ 222
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 91.3 bits (225), Expect = 6e-18
Identities = 135/469 (28%), Positives = 180/469 (38%), Gaps = 67/469 (14%)
Query: 880 DSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRR 939
D L R D+R D EG +S RGP G+ R ED + R R
Sbjct: 997 DKGLPRPDNR--DNRLEGN-----RGNSSSYRGP-------GQSRMEDTRDKGLVNRGR- 1041
Query: 940 LGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWR--NTDDDRP 997
G R P L +D D RR ++ +R DR R ++ + P
Sbjct: 1042 -GQAISRGPGLVKQED------FRDKMMGRREDSREKMNRGEGSRDRGLVRPGSSREKVP 1094
Query: 998 PRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTAD--EDRGPRRGMDDDRGPRRGGADD 1055
+DRG + + PPRR ++RG R A E PRR +RGP RG
Sbjct: 1095 GGLQGSQDRGA-AGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRGPGSR 1153
Query: 1056 ERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRR-GMDDDRGPRRGMDDDRGPRRGLD 1114
ER R+ DRGP R D G + D PR + G RG +
Sbjct: 1154 ERGLGRS---------DFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWN--HGEERGHE 1202
Query: 1115 DDRGPWRNADDDRIPRRGAEDDRGPWRNMD----DDRLSRRADDDRFP----RRGDDSRP 1166
+ RNA +R R D WR + DD L +DRF R D R
Sbjct: 1203 EFPLDGRNAPMER-ERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRR 1261
Query: 1167 GPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERE 1226
GPW W + E+ ++ RE ER+ DR+ +R D + D E +
Sbjct: 1262 GPW--------WDDWERDQDMDEDYNREM----ERDMDRDVDRISRPMDMYDRSLDNEWD 1309
Query: 1227 RDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRER 1286
RD R +D ++ R RD P D R DDR R++R RE RD R+R
Sbjct: 1310 RDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYR-DDRWREERNREHGYDRDFRDR 1368
Query: 1287 RDLR-DDRDRRGPPLRSEREEV---SSWRRADDRKDDRVEERDPPRRVP 1331
+LR + RG R +R+ V W R +R DR D R P
Sbjct: 1369 GELRIREYPERGDTWREKRDYVPDRMDWER--ERLSDRWYPSDVDRHSP 1415
Score = 88.2 bits (217), Expect = 5e-17
Identities = 132/431 (30%), Positives = 166/431 (38%), Gaps = 69/431 (16%)
Query: 987 PSWRNTDDDRPPRRIADEDR--GNWRHADDDRPPRRGLDEDRGSWRTADEDRGPR--RG- 1041
P N D PR ++R GN ++ R P + ED + RG RG
Sbjct: 990 PHSENNQDKGLPRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGP 1049
Query: 1042 ----MDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRG---PRRGMDDDRGPRRGMD 1094
+D R G +D R + R DRG P + G +G
Sbjct: 1050 GLVKQEDFRDKMMGRREDSREKMNRGEGSR--------DRGLVRPGSSREKVPGGLQG-S 1100
Query: 1095 DDRGPRRGMDDDRGPRRGLDDDRGPWRNADD-DRIP-RRGAEDDRGPWRNMDDDRLSRRA 1152
DRG G + PRR +RGP R A +RIP RR +RGP R
Sbjct: 1101 QDRGAA-GSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRGP--------G 1151
Query: 1153 DDDRFPRRGDDSRP-GPWRPLVKPGGWREKEKAREESWGPPR------ESRPSEEREWDR 1205
+R R D R GP+RP GG + R+E PPR E R EE D
Sbjct: 1152 SRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDE---PPRAPWNHGEERGHEEFPLDG 1208
Query: 1206 EK---ERDR-DNQDREENDKDPERERDRERDV----DREDRFRRP--RDEGGWRRGPAEE 1255
ER+R D+ DRE + E ERD + D +REDRF P R G RRGP
Sbjct: 1209 RNAPMERERLDDWDRERYWR--ECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPW-- 1264
Query: 1256 SSSWRDSSRRDDRDRD-DRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRAD 1314
W D R D D D +R ERD RD+ D DR + E + R
Sbjct: 1265 ---WDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRS-----LDNEWDRDYGRPL 1316
Query: 1315 DRKDDRVEERDPPRRVP----PPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKN 1370
D ++ + ERD P P PP DR RD E +E R +DR LR +
Sbjct: 1317 DEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREY 1376
Query: 1371 ETDEDGWTTVR 1381
D W R
Sbjct: 1377 PERGDTWREKR 1387
Score = 43.1 bits (100), Expect = 0.002
Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 16/94 (17%)
Query: 1196 RPSEEREWDREKERDR------DNQDREENDKDPERERDRER-----DVDREDRFRRPRD 1244
R +RE DRE DR D++D + D++ R+RDR+R D DR DR RRPRD
Sbjct: 1683 RDRYDRERDREPYFDRQSNVIADHRDFKR-DRETHRDRDRDRGVIDYDRDRFDRERRPRD 1741
Query: 1245 EGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERD 1278
+ R + SSRR DR R+ D
Sbjct: 1742 D----RAQSYRDKKDHSSSRRGGFDRPSYDRKSD 1771
Score = 40.4 bits (93), Expect = 0.012
Identities = 74/288 (25%), Positives = 99/288 (34%), Gaps = 65/288 (22%)
Query: 801 ERRITYYREKEEE------EQRRAEEQMLKERE---ERERAERAKREEELREYQERVKKL 851
E+ Y+R++ E+R EE L R ERER + RE RE
Sbjct: 1178 EKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYWRE-------- 1229
Query: 852 EEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRR 911
ER + LE+ RE R S SR D D G W E D +
Sbjct: 1230 --CERDYQDDTLELYNREDR-----------FSAPPSRSHDGDRRGPWWDDWERDQDMDE 1276
Query: 912 GPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDRE-----------------PSLRPDD 954
+E R RD DR R + R L ++ DR+ PSL P
Sbjct: 1277 DY-NREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLP 1335
Query: 955 DRVPRRGMDDDRGPRRGPEEDR-------FSRRGA------DDDRPSWRNTDDDRPPRRI 1001
P +D R R E +R F RG + +WR D P R
Sbjct: 1336 PLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMD 1395
Query: 1002 ADEDR--GNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRG 1047
+ +R W +D DR + E S + E G +D D+G
Sbjct: 1396 WERERLSDRWYPSDVDR--HSPMAEHMPSSHHSSEMMGSDASLDSDQG 1441
Score = 34.3 bits (77), Expect = 0.85
Identities = 41/164 (25%), Positives = 55/164 (33%), Gaps = 30/164 (18%)
Query: 1191 PPRESRPSEEREWDREKERDRDNQDREE----------NDKDPERERDRERDVDREDRFR 1240
PP P ++ D RD E+ D PER + DR+
Sbjct: 1628 PPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYD 1687
Query: 1241 RPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDL-RERRDLRDDRDRRGPP 1299
R RD + D D D +R+R+ RD R+R + DRDR
Sbjct: 1688 RERDR-----------EPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRE 1736
Query: 1300 LRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDR 1343
R + S+R D R D P S DR+ DR
Sbjct: 1737 RRPRDDRAQSYRDKKDHSSSRRGGFDRP--------SYDRKSDR 1772
Score = 34.3 bits (77), Expect = 0.85
Identities = 39/121 (32%), Positives = 55/121 (45%), Gaps = 29/121 (23%)
Query: 1249 RRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVS 1308
R P E S++ ++ RDR DR R+R+ D R+ + D RD +
Sbjct: 1665 RPDPLPERSTF-ETEHAGQRDRYDRERDREPYFD-RQSNVIADHRDFKR----------- 1711
Query: 1309 SWRRADDRKDDRVEERDPPRRVPPPALSRDRERDR-DREREGEKEKA-SWRAEKDRESLR 1366
DR+ R +RD R V D +RDR DRER ++A S+R +KD S R
Sbjct: 1712 ------DRETHRDRDRD--RGVI------DYDRDRFDRERRPRDDRAQSYRDKKDHSSSR 1757
Query: 1367 R 1367
R
Sbjct: 1758 R 1758
Score = 33.5 bits (75), Expect = 1.5
Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 29/139 (20%)
Query: 927 DRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDR 986
DR RD +R R + D DR+ R D +R PR DDR ++D S R DR
Sbjct: 1712 DRETHRDRDRDRGV-IDYDRD---RFDRERRPR----DDRAQSYRDKKDHSSSRRGGFDR 1763
Query: 987 PSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDR 1046
PS+ DR DRP G G RT E+R P
Sbjct: 1764 PSY-----DR----------------KSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSH 1802
Query: 1047 GPRRGGADDERSSWRNADD 1065
P +++ +N DD
Sbjct: 1803 QPPPAPRVEKKPESKNVDD 1821
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 89.7 bits (221), Expect = 2e-17
Identities = 62/200 (31%), Positives = 104/200 (52%), Gaps = 27/200 (13%)
Query: 1182 EKAREESWGPPRESRPSEEREWDREKERDRDNQDREEN---DKDPERERDRERDVDREDR 1238
E+ RE RE+ +E E +R+++R+R+NQ EN +D RERDR+ D ++E
Sbjct: 2 ERQRERK----RETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERE 57
Query: 1239 FRRPRDEGGWRRGPAE-ESSSWRDSSRRDDRDRD-DRRRERDDRRDLRERRDLRDDRDRR 1296
++ RD R E E+ R+ R+ +R R DR R++D R+ + D +R+R+
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRK 117
Query: 1297 GPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASW 1356
G R ++ E R DR+ +R +R+ R+R+R R+R+RE ++E+ W
Sbjct: 118 GGRERDKQTE-----RERDRERERQRQRE-----------RERQRQRERKRETDRERQRW 161
Query: 1357 --RAEKDRESLRRTKNETDE 1374
R E+ +E + K E E
Sbjct: 162 AEREERKKERKKERKKERKE 181
Score = 85.1 bits (209), Expect = 4e-16
Identities = 61/198 (30%), Positives = 98/198 (49%), Gaps = 31/198 (15%)
Query: 1179 REKEKAREESWGPPRESRPSEEREWDREKERDR--DNQDREENDKDPERERDRERDVDRE 1236
RE+++ RE RE+R R+ DR +ERDR D + E K+ +R+R RER+ +RE
Sbjct: 19 RERDRQRERENQTERENR---HRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE 75
Query: 1237 DRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRR 1296
+R R R+ R + R D+DRD R+ DR R R+ R +RD+
Sbjct: 76 TERQRERQRQRERK---------RQTDRERDKDRDRERKRETDRNRERNRKGGR-ERDK- 124
Query: 1297 GPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASW 1356
++ERE R R+ +R +R+ R RE DR+R+R E+E+
Sbjct: 125 ----QTERERDRERERQRQRERERQRQRE-----------RKRETDRERQRWAEREERKK 169
Query: 1357 RAEKDRESLRRTKNETDE 1374
+K+R+ R+ K + ++
Sbjct: 170 ERKKERKKERKEKKKEEK 187
Score = 80.9 bits (198), Expect = 8e-15
Identities = 61/232 (26%), Positives = 105/232 (45%), Gaps = 38/232 (16%)
Query: 1126 DRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAR 1185
+R R E DRG + DR R + R R++++ R
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRH-----------------RQRDRHR 44
Query: 1186 EESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDE 1245
E R+ + E+E +R+KERDR Q E +++ ER+R+R+R +R+ + R RD+
Sbjct: 45 E------RDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK 98
Query: 1246 GGWRRGPAEESSSWRDSSRRDDRDRDDR-RRERDDRRDLRERRDLRDDRDRRGPPLRSER 1304
R E + R+ +R+ R+RD + RERD R+ + +R+ +R R+ R
Sbjct: 99 DRDRERKRETDRN-RERNRKGGRERDKQTERERDRERERQRQRE--RERQRQRERKRETD 155
Query: 1305 EEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASW 1356
E W ++RK +R +ER ++R+ + E+ E +K W
Sbjct: 156 RERQRWAEREERKKERKKER-----------KKERKEKKKEEKRREDKKRKW 196
Score = 76.3 bits (186), Expect = 2e-13
Identities = 58/208 (27%), Positives = 101/208 (48%), Gaps = 13/208 (6%)
Query: 715 EEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEE 774
+ +R ++ D ++ E ER + E + E+++R +RD R K + +
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Query: 775 KLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAER 834
+ +Q ER E R ER+RQR+ +R+ R+K+ + +R+ E +ER + ER
Sbjct: 64 RQRQ-RERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122
Query: 835 AKREEELREYQERVKKLEEVERKKRQRELEIE-ERERRREEERRLGDSSLSRKDSRWGDR 893
K+ E R+ +ER ++ + ++RQRE + E +RER+R ER RK R +R
Sbjct: 123 DKQTERERD-RERERQRQRERERQRQRERKRETDRERQRWAERE------ERKKERKKER 175
Query: 894 DSEGTWRKGPEADSEWRRGPPEKEWRRG 921
E +K E RR +++W G
Sbjct: 176 KKERKEKK----KEEKRREDKKRKWGEG 199
Score = 75.9 bits (185), Expect = 3e-13
Identities = 61/230 (26%), Positives = 104/230 (45%), Gaps = 35/230 (15%)
Query: 715 EEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSR--MLEDRDLFVMRLKAARQSVY 772
E QR + + +E ER Q ERE E +NR + +RD R K +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 773 EEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERA 832
++ +Q ER E R ER+RQR+ +R+ R+K+ + +R+ E +ER +
Sbjct: 62 RDRQRQ-RERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGR 120
Query: 833 ERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGD 892
ER K+ E R+ ++RQR+ ERER+R+ ER+ R+ RW +
Sbjct: 121 ERDKQTERERD-----------RERERQRQ---RERERQRQRERK---RETDRERQRWAE 163
Query: 893 RDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGD 942
R+ R K+ R+ E +++ + +R E++ R+ G+
Sbjct: 164 RE---------------ERKKERKKERKKERKEKKKEEKRREDKKRKWGE 198
Score = 74.7 bits (182), Expect = 6e-13
Identities = 57/205 (27%), Positives = 94/205 (45%), Gaps = 18/205 (8%)
Query: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLE 852
ER+R+RK E E+E + QR E Q +E R+R +R+ + +ER ++ E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 853 EVERKKRQRELEIE---ERERRREEER-----RLGDSSLSRKDSRWGDRDSEGTWRKGPE 904
+++R+RE E E +RER+R+ ER R D R+ R DR+ E + G E
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
Query: 905 ADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDD 964
D + E+E R R R R +R R+ D +R+ ++ + R+
Sbjct: 122 RDKQ-----TERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK---K 173
Query: 965 DRGPRRGPEEDRFSRRGADDDRPSW 989
+R R ++ RR +D + W
Sbjct: 174 ERKKERKEKKKEEKRR--EDKKRKW 196
Score = 72.8 bits (177), Expect = 2e-12
Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 40/221 (18%)
Query: 675 EQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEE--R 732
++ E+E+ +ER E++ + +R + E E +R K+ D Q+E E R
Sbjct: 15 KETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETER 74
Query: 733 ITTMQLEREKALEHKNRMSRMLE-DRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRL 791
T Q ER++ E K + R + DRD ER E NR
Sbjct: 75 ETERQRERQRQRERKRQTDRERDKDRD---------------------RERKRETDRNRE 113
Query: 792 EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKL 851
RK R+ +++ R++E E QR+ E + ++RE + +R ER +
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDR-----------ERQRWA 162
Query: 852 EEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGD 892
E ERKK +++ +ER+ +++EE+R D K +WG+
Sbjct: 163 EREERKKERKKERKKERKEKKKEEKRRED-----KKRKWGE 198
Score = 70.9 bits (172), Expect = 8e-12
Identities = 45/178 (25%), Positives = 80/178 (44%), Gaps = 3/178 (1%)
Query: 774 EKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAE 833
E+ +Q E ER NR +R R R+ +R+ REKE E Q+ + Q +ERE E
Sbjct: 20 ERDRQRERENQTERENRHRQRDRHRERDRQTD--REKERERQKERDRQRQRERETERETE 77
Query: 834 RAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDR 893
R + + RE + + + + +R R+R+ E + R + R D R+ R +R
Sbjct: 78 RQRERQRQRERKRQTDRERDKDRD-RERKRETDRNRERNRKGGRERDKQTERERDRERER 136
Query: 894 DSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLR 951
+ + + + + + W E R ++R R +ER + +++ RE R
Sbjct: 137 QRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 68.2 bits (165), Expect = 5e-11
Identities = 50/169 (29%), Positives = 81/169 (47%), Gaps = 30/169 (17%)
Query: 1224 ERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRD-DRRRERDDRRD 1282
ER+R+R+R+ DR R RD R E R++R R DR RERD + D
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTE----------RENRHRQRDRHRERDRQTD 51
Query: 1283 LRERRDLRDDRDR---------RGPPLRSEREEVSSWRRADDRKDDRVEERDPPR----- 1328
+ R+ + +RDR R + ER+ +R DR+ D+ +R+ R
Sbjct: 52 REKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
Query: 1329 --RVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDED 1375
R RD++ +R+R+RE E+++ + E++R+ R K ETD +
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQR---QRERERQRQRERKRETDRE 157
Score = 66.2 bits (160), Expect = 2e-10
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 15/200 (7%)
Query: 776 LKQFEERLAEERHNRLEERKRQRKEER-----RITYYREKEEEEQRRAEEQMLKERE-ER 829
+++ ER E + ER+R R+ ER R +R+++ +R + KERE ++
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 830 ERAERAKREEELREYQERVKKLEEVERKKRQRELEIE---ERERRREEERRLGDSSLSRK 886
ER + +RE E ER ++ + +KRQ + E + +RER+RE +R + +RK
Sbjct: 61 ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR---NRERNRK 117
Query: 887 DSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDR 946
R D+ +E R+ R+ E++ +R R+ DR +R ER R + +
Sbjct: 118 GGRERDKQTE---RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKE 174
Query: 947 EPSLRPDDDRVPRRGMDDDR 966
R + + +R D R
Sbjct: 175 RKKERKEKKKEEKRREDKKR 194
Score = 62.8 bits (151), Expect = 2e-09
Identities = 60/227 (26%), Positives = 91/227 (40%), Gaps = 29/227 (12%)
Query: 1025 DRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMD 1084
+R R + DRG + DR R + + R D R R D ++ R +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 1085 DDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMD 1144
DR +R + +R R + R R DR D DR R E DR RN
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDR----ERDKDRDRERKRETDRNRERN-- 115
Query: 1145 DDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWD 1204
R R D + R D R R++++ RE R+ + +RE D
Sbjct: 116 --RKGGRERDKQTERERDRERE------------RQRQRERE------RQRQRERKRETD 155
Query: 1205 REKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRG 1251
RE++R +REE K+ ++ER +ER +++ RR + W G
Sbjct: 156 RERQR---WAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
Score = 62.4 bits (150), Expect = 3e-09
Identities = 55/203 (27%), Positives = 85/203 (41%), Gaps = 24/203 (11%)
Query: 1096 DRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDD 1155
+R R + DRG + DR R +R R + DR R+ DR R
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTER-ENRHRQRDRHRERDRQTDREKERERQK 60
Query: 1156 RFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRD--- 1212
R+ R RE E+ RE RE + +RE D++++R+R
Sbjct: 61 ERDRQRQRERETE----------RETERQRERQ--RQRERKRQTDRERDKDRDRERKRET 108
Query: 1213 --NQDR-----EENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRR 1265
N++R E DK ERERDRER+ R+ R R +R E W + R
Sbjct: 109 DRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRER-KRETDRERQRWAEREER 167
Query: 1266 DDRDRDDRRRERDDRRDLRERRD 1288
+ +R++ER +++ +RR+
Sbjct: 168 KKERKKERKKERKEKKKEEKRRE 190
Score = 57.8 bits (138), Expect = 7e-08
Identities = 67/269 (24%), Positives = 117/269 (43%), Gaps = 76/269 (28%)
Query: 590 EKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELG 649
E++ +RE + + ++ E ER RQ +E + ER E+ ++ RER Q +
Sbjct: 2 ERQRERKRETD--RGKETERERDRQRERENQTER---ENRHRQRDRHRERDRQTDR---- 52
Query: 650 AKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPL 709
+ E+E+++ ++R + +E++ + +R
Sbjct: 53 --------------------------EKERERQKERDRQRQRERETERETERQR------ 80
Query: 710 IKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQ 769
E QR Q+E +R T + ++++ E K R E K R
Sbjct: 81 -----ERQR--------QRERKRQTDRERDKDRDRERKRETDRNRE------RNRKGGR- 120
Query: 770 SVYEEKLKQFE-ERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREE 828
E+ KQ E ER E R ER+RQR+ ER+ RE + E QR A EREE
Sbjct: 121 ----ERDKQTERERDRERERQRQRERERQRQRERK----RETDRERQRWA------EREE 166
Query: 829 RERAERAKREEELREYQERVKKLEEVERK 857
R++ + +R++E +E ++ K+ E+ +RK
Sbjct: 167 RKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 55.5 bits (132), Expect = 4e-07
Identities = 51/205 (24%), Positives = 77/205 (37%), Gaps = 34/205 (16%)
Query: 836 KREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDS 895
+R+ E + +R K+ E ++R+RE + E R R+ +R R+ R DR
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRH-------RERDRQTDR-- 52
Query: 896 EGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDD 955
EKE R + RD R R+ ER + RE + +
Sbjct: 53 -------------------EKERERQKERDRQRQRERETERE----TERQRERQRQRERK 89
Query: 956 RVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDD 1015
R R D DR R E DR R R + T+ +R R + R R
Sbjct: 90 RQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRER--ERQRQRERERQRQ 147
Query: 1016 RPPRRGLDEDRGSWRTADEDRGPRR 1040
R +R D +R W +E + R+
Sbjct: 148 RERKRETDRERQRWAEREERKKERK 172
Score = 55.1 bits (131), Expect = 5e-07
Identities = 48/191 (25%), Positives = 93/191 (48%), Gaps = 22/191 (11%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILAR-RQTIEER-KERLESLNIQREKEELEQREAEL 601
+E++ Q + +N ++ R R RQT E+ +ER + + QR++E +RE E
Sbjct: 19 RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETER 78
Query: 602 QKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDL 661
Q+ R+ + ER RQ +ER+K+R + K++T R R E K ++ D +
Sbjct: 79 QRERQRQRERKRQTDRERDKDR----DRERKRETDRNR-------ERNRKGGRERDKQTE 127
Query: 662 EELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKD 721
E D + E++++ +ER + +E+K + +R E K +++R K+
Sbjct: 128 RERD---------RERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKE 178
Query: 722 MDLWEQQEEER 732
+++E+ R
Sbjct: 179 RKEKKKEEKRR 189
Score = 53.5 bits (127), Expect = 1e-06
Identities = 50/203 (24%), Positives = 93/203 (45%), Gaps = 21/203 (10%)
Query: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELE-QREAELQKVRKAEEERLRQEAKERE 620
++E +R R + E ++R Q E+E QR+ ++ R+ + E+ R+ KER+
Sbjct: 4 QRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERD 63
Query: 621 KERILQEHEQIKKKTVRERLEQ---IKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQL 677
++R Q + +++T R+R Q +K + + KD D E E D
Sbjct: 64 RQR--QRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETD---------RNR 112
Query: 678 EKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQ---QEEERIT 734
E+ +K +ER K E++ D +R E + + +R ++ D Q + EER
Sbjct: 113 ERNRKGGRERDKQTERERDRERERQRQRE---RERQRQRERKRETDRERQRWAEREERKK 169
Query: 735 TMQLEREKALEHKNRMSRMLEDR 757
+ ER+K + K + + ED+
Sbjct: 170 ERKKERKKERKEKKKEEKRREDK 192
Score = 52.8 bits (125), Expect = 2e-06
Identities = 42/175 (24%), Positives = 73/175 (41%), Gaps = 13/175 (7%)
Query: 900 RKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPR 959
++ + E R + R + E+R +RD R R D ++E + + DR +
Sbjct: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQ 67
Query: 960 RGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPR 1019
R + +R R E R R DR R+ D DR +R D +R +R +
Sbjct: 68 RERETERETERQRERQRQRERKRQTDRE--RDKDRDRERKRETDRNR--------ERNRK 117
Query: 1020 RGLDEDRGSWRTADEDRGPRRGMDDDR---GPRRGGADDERSSWRNADDDRGPRR 1071
G + D+ + R D +R +R + +R R+ D ER W ++ + R+
Sbjct: 118 GGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
Score = 52.4 bits (124), Expect = 3e-06
Identities = 58/248 (23%), Positives = 105/248 (42%), Gaps = 62/248 (25%)
Query: 576 EERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKT 635
E ++E +RE++ +RE + ++ E R RQ + RE++R ++ +++
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTER-----ENRHRQRDRHRERDRQTDREKERERQK 60
Query: 636 VRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKI 695
R+R Q ++ + E+E + +ER + +E+K
Sbjct: 61 ERDRQRQRER------------------------------ETERETERQRERQRQRERKR 90
Query: 696 DY-FERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRML 754
ER K + E +R D + ++ R Q ERE+ E + + R
Sbjct: 91 QTDRERDKDRDR--------ERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRER 142
Query: 755 EDRDLFVMRLKAARQSVYEEKLKQFEERLA-EERHNRLEERKRQRKEERRITYYREKEEE 813
E RQ E K + ER ER R +ERK++RK+ER +EK++E
Sbjct: 143 E------------RQRQRERKRETDRERQRWAEREERKKERKKERKKER-----KEKKKE 185
Query: 814 EQRRAEEQ 821
E+RR +++
Sbjct: 186 EKRREDKK 193
Score = 50.4 bits (119), Expect = 1e-05
Identities = 50/199 (25%), Positives = 75/199 (37%), Gaps = 29/199 (14%)
Query: 867 ERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR-RGEGRD 925
+RER+RE +R ++ R DR E R E+E R R R
Sbjct: 4 QRERKRETDR-------GKETERERDRQRE-------------RENQTERENRHRQRDRH 43
Query: 926 EDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDD 985
+R + D E+ R + DR+ + +R R + R R + DR R D D
Sbjct: 44 RERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDR--ERDKDRD 101
Query: 986 RPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDD 1045
R R TD +R + +R R D R + +R R + R R + D
Sbjct: 102 RERKRETDRNR------ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
Query: 1046 RGPRRGGADDERSSWRNAD 1064
R +R +ER R +
Sbjct: 156 RERQRWAEREERKKERKKE 174
Score = 47.4 bits (111), Expect = 1e-04
Identities = 56/238 (23%), Positives = 91/238 (38%), Gaps = 46/238 (19%)
Query: 995 DRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGAD 1054
+R R + DRG + DR R +R + R DR R DR R +
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTEREN-RHRQRDRHRERDRQTDREKER---E 57
Query: 1055 DERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLD 1114
++ R +R R + R +R + R R D DR R + DR
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR------- 110
Query: 1115 DDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVK 1174
+ +R + G E D+ R D +R +R +
Sbjct: 111 ---------NRERNRKGGRERDKQTERERDRERERQRQRE-------------------- 141
Query: 1175 PGGWREKEKAREESWGPPRESRPSEEREWDREKERDRD-NQDREENDKDPERERDRER 1231
RE+++ RE RE + ERE +R+KER ++ ++R+E K+ +R D++R
Sbjct: 142 ----RERQRQRERKRETDRERQRWAERE-ERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 43.5 bits (101), Expect = 0.001
Identities = 46/208 (22%), Positives = 82/208 (39%), Gaps = 15/208 (7%)
Query: 915 EKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPR-RGMDDDRGPRRGPE 973
E++ R D + R+ +R R + +RE R D R R D ++ R E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 974 EDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTAD 1033
DR +R +R + R T+ R +R + R R D DR R + DR +
Sbjct: 62 RDRQRQR----ERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR------N 111
Query: 1034 EDRGPRRGMD-DDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRG 1092
+R + G + D + R + ER R + R R + DR +R + + +
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
Query: 1093 MDDDRGPRRGMDDDRGPRRGLDDDRGPW 1120
+ + R+ + + + +D + W
Sbjct: 172 KKERKKERK---EKKKEEKRREDKKRKW 196
Score = 40.8 bits (94), Expect = 0.009
Identities = 29/96 (30%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 559 KNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAE--LQKVRKAEEERLRQ-- 614
+ ++E R R + +++ RE+E QRE E Q+ RK E +R RQ
Sbjct: 102 RERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRW 161
Query: 615 -EAKEREKERILQEHEQIKKKTVRERLEQIKKTELG 649
E +ER+KER + ++ K+K E+ + KK + G
Sbjct: 162 AEREERKKERKKERKKERKEKKKEEKRREDKKRKWG 197
Score = 38.9 bits (89), Expect = 0.035
Identities = 28/117 (23%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 544 QEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQK 603
+++E Q Q R + + +R+T R+ + RE+++ +RE + ++
Sbjct: 78 RQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG---GRERDKQTERERDRER 134
Query: 604 VRKAEEERLRQEAKEREKERILQ-----EHEQIKKKTVRERLEQIKKTELGAKAFKD 655
R+ + ER RQ +ER++E + E E+ KK+ +ER ++ K+ + K +D
Sbjct: 135 ERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRRED 191
Score = 36.2 bits (82), Expect = 0.22
Identities = 19/76 (25%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 1300 LRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAE 1359
+ +RE R + + +R +R+ + R R+R R+R+R+ ++EK R +
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERER-Q 59
Query: 1360 KDRESLRRTKNETDED 1375
K+R+ R+ + ET+ +
Sbjct: 60 KERDRQRQRERETERE 75
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 89.7 bits (221), Expect = 2e-17
Identities = 146/687 (21%), Positives = 271/687 (39%), Gaps = 81/687 (11%)
Query: 437 LRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSD 496
LR +++ ++ + L A + +R + +A H + + + ++ L
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEA--HAQAKAQAEREAKELQQRMQ 1398
Query: 497 LNYATREDAPIGPHLQSMPSEQIRNQLTAMSS--VLAKAL-------------EVIKPAH 541
RE+A + Q ++ QL S + AKA E I+
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1458
Query: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL 601
+ E E+ + L+ R + A+++ +E ERL +Q E + Q E EL
Sbjct: 1459 LQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRR-QVQDESQRKRQAEVEL 1517
Query: 602 QKVRKAEEERLRQEAKEREK-ERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
KAE E R++ + + E + + E+ +++ + +E+ ++ ++ + + +
Sbjct: 1518 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAE 1577
Query: 661 LEELDPDFIMAKQVEQLEKEKKE-------LQERLKNQEKKIDYFERAKRLEEIPLIKSA 713
L+ F A++ QLE+ +E L+E + + ++ ERA+ E L +
Sbjct: 1578 LQSKRASF--AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ 1635
Query: 714 YEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRM--------LEDRDLFVMRLK 765
+ + L ++ ++ + Q E EK E R +R + R+L L+
Sbjct: 1636 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1695
Query: 766 AARQ---SVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAE--E 820
RQ +++L +E + E++RQ EE RE Q+R E
Sbjct: 1696 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Query: 821 QMLKEREERE--RAERAKREEELREYQERVKKLEEVE-------------------RKKR 859
++ K R E E A +A+ EEE R E+ K+ E E KR
Sbjct: 1756 ELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKR 1815
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
QR+L E+ R+R E R+ L+ K + G+ R EA+ + E E
Sbjct: 1816 QRQLAEEDAARQRAEAERV----LAEKLAAIGE-----ATRLKTEAEIALKEKEAENERL 1866
Query: 920 RGEGRDEDRSHRR-DEERPRRLGDDEDREPSLR--PDDDRVPRRGMDDDRGPRRGPEEDR 976
R DE RR +E+ + D E+R LR D + ++G+ +D +R E+
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1926
Query: 977 FSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDR 1036
A ++ + + + RI R + + L+ R A+E+R
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-----QAELEAARQRQLAAEEER 1981
Query: 1037 GPRRGMDDDRGPRRGGADDERSSWRNA 1063
RR ++R + A++E + R A
Sbjct: 1982 --RRREAEERVQKSLAAEEEAARQRKA 2006
Score = 88.2 bits (217), Expect = 5e-17
Identities = 208/1021 (20%), Positives = 394/1021 (38%), Gaps = 135/1021 (13%)
Query: 415 REQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLER----A 470
R + E E EL+++ QL+ N LRL Q ++ Q ++ + +A + R A
Sbjct: 1622 RAREEAERELERW--QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1679
Query: 471 IVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVL 530
A R +L + R L+ G+ E I ++ EQ R L + L
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 531 AKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQRE 590
+ + A Q+++E + A L R E + +LA + EE + QR
Sbjct: 1740 QR-----EAAAATQKRQE-----LEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQR- 1788
Query: 591 KEELEQREAELQKVRKAEEE--RLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEL 648
EAE + R+ EE RLR A+E +++R L E + +++ ER+ K +
Sbjct: 1789 ------LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842
Query: 649 G-----------AKAFKDIDIEDLEELDPD--FIMAKQVEQLEKEKKELQERLKNQEKKI 695
G A K+ + E L L D F + EQ + K +++ERL K
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1902
Query: 696 DY-FERAKRL------------EEIPLIKSAYEEQRIKDMDLW----------------- 725
D ER K L EEI +K+++E+ +L
Sbjct: 1903 DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1962
Query: 726 EQQEEERITTMQL---EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEER 782
EQ E E QL E + E + R+ + L + + KAA + V K K E R
Sbjct: 1963 EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2022
Query: 783 LAEERHNRLEER----------KRQRKEERRITY-YREKEEEEQRRAEEQMLKEREERER 831
ER + R KR + EE+ + ++KE+E Q+ +++ + R
Sbjct: 2023 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2082
Query: 832 AERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWG 891
AE A+R EE E + Q E E + R+ EE RL S+ + +R
Sbjct: 2083 AEAARR------------AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2130
Query: 892 DRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRD-EDRSHRRDEERPRRLG--------- 941
+ + RK E ++ R + R+ + D E H++ E+ R
Sbjct: 2131 AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2190
Query: 942 -----DDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRN----- 991
++ D + +L ++ + + + R EE+ FS R ++ +
Sbjct: 2191 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Query: 992 ------TDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDD 1045
D D R + +E + A++ E + A+ED +R + +
Sbjct: 2251 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 1046 RGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDD 1105
+ A E + + + ++ L ++ R D ++ ++ ++ +G +R ++
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 1106 DRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDD-DRLSRRADDDRFPRRGDDS 1164
+R +R L+ +A+ +R+ R AE R R +D R ++A++ +
Sbjct: 2371 ER--QRQLE------MSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2422
Query: 1165 RPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPE 1224
LV+ + ++ + RE+ ERE ++ ++ + Q + E + +
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAE--RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2480
Query: 1225 RERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLR 1284
+E+ + + F +D R E+ + + +D+ + + RE R
Sbjct: 2481 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ----R 2536
Query: 1285 ERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRD 1344
+++ + +R R + R RK + +++ + RR L+ + +R R+
Sbjct: 2537 QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2596
Query: 1345 R 1345
+
Sbjct: 2597 Q 2597
Score = 75.1 bits (183), Expect = 4e-13
Identities = 81/392 (20%), Positives = 181/392 (46%), Gaps = 47/392 (11%)
Query: 480 LQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKP 539
LQ + + + L+ A +E A L+ + E + Q +L + ++ ++
Sbjct: 2266 LQEEAEKMKQVAEEAARLSVAAQEAA----RLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2321
Query: 540 AHILQ-EKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQRE 598
A L+ E E Q A + R + + +Q EE + +L +R+++ E
Sbjct: 2322 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381
Query: 599 AELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDI 658
AE K+R AE R + A+E + +R ++ E+I +K R L +K L + ++I
Sbjct: 2382 AERLKLRVAEMSRAQARAEE-DAQRFRKQAEEIGEKLHRTELATQEKVTL----VQTLEI 2436
Query: 659 EDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQR 718
+ + + + + +LE+EK++LQ+ AK L+
Sbjct: 2437 QRQQSDHDAERLREAIAELEREKEKLQQE-------------AKLLQ------------- 2470
Query: 719 IKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQ 778
+K ++ Q+E+ + Q ++ L K+ + + R+ F+ + KA + ++++++ +
Sbjct: 2471 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ----RERFIEQEKAKLEQLFQDEVAK 2526
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKRE 838
++ E++ ++++ +E +R+ E+ Q AEE + +++EE ++ E+ +R+
Sbjct: 2527 AQQLREEQQR----QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Query: 839 EE--LREYQERVK-KLEEVERKKRQRELEIEE 867
+E L E +R++ +L+ +E + R EE
Sbjct: 2583 QEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Score = 65.9 bits (159), Expect = 3e-10
Identities = 188/946 (19%), Positives = 362/946 (38%), Gaps = 135/946 (14%)
Query: 491 LSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQH 550
LS ++ A E +P P L+S E +L + S+ A LE +K ++ +
Sbjct: 1043 LSAEAEKVLALPEPSPAAPTLRS-ELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGA 1101
Query: 551 QLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEE- 609
+ + A+ + KE Q + A +E K L+ L Q E ++ +A ++R A+E
Sbjct: 1102 EEVLRAH-EEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ-PTFDALRDELRGAQEV 1159
Query: 610 -ERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668
ERL+Q ER+ ++ + RER+ Q+ + A D+ +LE+L
Sbjct: 1160 GERLQQRHGERD----------VEVERWRERVAQLLERWQAVLAQTDVRQRELEQL---- 1205
Query: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQ 728
+Q+ + L L++ + R ++++ +PL S Q +++ EQ
Sbjct: 1206 --GRQLRYYRESADPLGAWLQDARR------RQEQIQAMPLADS----QAVREQLRQEQA 1253
Query: 729 EEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVY----EEKLKQFEERLA 784
E I + E+ + ++D +L ++ KA + V + K++ E +
Sbjct: 1254 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1313
Query: 785 EE------RHNRL------------EERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
+E ++ L E +R +EER R +E E E + K+R
Sbjct: 1314 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR 1373
Query: 827 E--ERERAERAKREEELREYQERVKK-------------------LEEVERKKRQRELEI 865
+ E +A+ E E +E Q+R+++ EE+++ ++ E EI
Sbjct: 1374 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1433
Query: 866 EERER----------RREEERRLGDSSLSRKDSRWGDRDSE--GTWRKGPEADSEWRRGP 913
+ + R R EEE R+ L + + G + E + EA+++ R+
Sbjct: 1434 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1493
Query: 914 PEKEWRRGEGRDEDRSHRRDE-ERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGP 972
E E R + +DE + R+ E E R+ + + R +R + R
Sbjct: 1494 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA--------REKQRALQALEELRLQA 1545
Query: 973 EEDRFSRRGADDDRPSWRNTDDDRPPRRI-ADEDRGNWRHADDDRPPRRGLDEDRGSWRT 1031
EE R A+ +R + R A+ A+ R L E+ +
Sbjct: 1546 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1605
Query: 1032 ADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRR 1091
E+ R + R A+ E W+ ++ R ++ ++ + ++
Sbjct: 1606 LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1665
Query: 1092 GMDDDR-GPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSR 1150
+ +R RRG +++ R+ R AE + R + + +
Sbjct: 1666 KEEAEREARRRGKAEEQAVRQ------------------RELAEQELEKQRQLAEGTAQQ 1707
Query: 1151 R--ADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKE 1208
R A+ + R + + R L++ R + +A + R+ +E + E E
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT--QKRQELEAELAKVRAEME 1765
Query: 1209 RDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDR 1268
++ R E + E+ ++R RFR +E R AEE+ R +
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLA----- 1820
Query: 1269 DRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPR 1328
+ D R+ + R L E+ + R L++E E + A++ + R+ E + +
Sbjct: 1821 EEDAARQRAEAERVLAEKLAAIGEATR----LKTEAEIALKEKEAENERLRRLAEDEAFQ 1876
Query: 1329 RVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDE 1374
R R E+ + + E+ A R D E L R K ++
Sbjct: 1877 R------RRLEEQAAQHKADIEERLAQLRKASDSE-LERQKGLVED 1915
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 89.7 bits (221), Expect = 2e-17
Identities = 146/687 (21%), Positives = 271/687 (39%), Gaps = 81/687 (11%)
Query: 437 LRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSD 496
LR +++ ++ + L A + +R + +A H + + + ++ L
Sbjct: 1345 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEA--HAQAKAQAEREAKELQQRMQ 1402
Query: 497 LNYATREDAPIGPHLQSMPSEQIRNQLTAMSS--VLAKAL-------------EVIKPAH 541
RE+A + Q ++ QL S + AKA E I+
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1462
Query: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL 601
+ E E+ + L+ R + A+++ +E ERL +Q E + Q E EL
Sbjct: 1463 LQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRR-QVQDESQRKRQAEVEL 1521
Query: 602 QKVRKAEEERLRQEAKEREK-ERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
KAE E R++ + + E + + E+ +++ + +E+ ++ ++ + + +
Sbjct: 1522 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAE 1581
Query: 661 LEELDPDFIMAKQVEQLEKEKKE-------LQERLKNQEKKIDYFERAKRLEEIPLIKSA 713
L+ F A++ QLE+ +E L+E + + ++ ERA+ E L +
Sbjct: 1582 LQSKRASF--AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ 1639
Query: 714 YEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRM--------LEDRDLFVMRLK 765
+ + L ++ ++ + Q E EK E R +R + R+L L+
Sbjct: 1640 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1699
Query: 766 AARQ---SVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAE--E 820
RQ +++L +E + E++RQ EE RE Q+R E
Sbjct: 1700 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1759
Query: 821 QMLKEREERE--RAERAKREEELREYQERVKKLEEVE-------------------RKKR 859
++ K R E E A +A+ EEE R E+ K+ E E KR
Sbjct: 1760 ELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKR 1819
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
QR+L E+ R+R E R+ L+ K + G+ R EA+ + E E
Sbjct: 1820 QRQLAEEDAARQRAEAERV----LAEKLAAIGE-----ATRLKTEAEIALKEKEAENERL 1870
Query: 920 RGEGRDEDRSHRR-DEERPRRLGDDEDREPSLR--PDDDRVPRRGMDDDRGPRRGPEEDR 976
R DE RR +E+ + D E+R LR D + ++G+ +D +R E+
Sbjct: 1871 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1930
Query: 977 FSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDR 1036
A ++ + + + RI R + + L+ R A+E+R
Sbjct: 1931 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-----QAELEAARQRQLAAEEER 1985
Query: 1037 GPRRGMDDDRGPRRGGADDERSSWRNA 1063
RR ++R + A++E + R A
Sbjct: 1986 --RRREAEERVQKSLAAEEEAARQRKA 2010
Score = 88.2 bits (217), Expect = 5e-17
Identities = 208/1021 (20%), Positives = 394/1021 (38%), Gaps = 135/1021 (13%)
Query: 415 REQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLER----A 470
R + E E EL+++ QL+ N LRL Q ++ Q ++ + +A + R A
Sbjct: 1626 RAREEAERELERW--QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1683
Query: 471 IVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVL 530
A R +L + R L+ G+ E I ++ EQ R L + L
Sbjct: 1684 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1743
Query: 531 AKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQRE 590
+ + A Q+++E + A L R E + +LA + EE + QR
Sbjct: 1744 QR-----EAAAATQKRQE-----LEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQR- 1792
Query: 591 KEELEQREAELQKVRKAEEE--RLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEL 648
EAE + R+ EE RLR A+E +++R L E + +++ ER+ K +
Sbjct: 1793 ------LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1846
Query: 649 G-----------AKAFKDIDIEDLEELDPD--FIMAKQVEQLEKEKKELQERLKNQEKKI 695
G A K+ + E L L D F + EQ + K +++ERL K
Sbjct: 1847 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1906
Query: 696 DY-FERAKRL------------EEIPLIKSAYEEQRIKDMDLW----------------- 725
D ER K L EEI +K+++E+ +L
Sbjct: 1907 DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1966
Query: 726 EQQEEERITTMQL---EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEER 782
EQ E E QL E + E + R+ + L + + KAA + V K K E R
Sbjct: 1967 EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2026
Query: 783 LAEERHNRLEER----------KRQRKEERRITY-YREKEEEEQRRAEEQMLKEREERER 831
ER + R KR + EE+ + ++KE+E Q+ +++ + R
Sbjct: 2027 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2086
Query: 832 AERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWG 891
AE A+R EE E + Q E E + R+ EE RL S+ + +R
Sbjct: 2087 AEAARR------------AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2134
Query: 892 DRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRD-EDRSHRRDEERPRRLG--------- 941
+ + RK E ++ R + R+ + D E H++ E+ R
Sbjct: 2135 AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2194
Query: 942 -----DDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRN----- 991
++ D + +L ++ + + + R EE+ FS R ++ +
Sbjct: 2195 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2254
Query: 992 ------TDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDD 1045
D D R + +E + A++ E + A+ED +R + +
Sbjct: 2255 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2314
Query: 1046 RGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDD 1105
+ A E + + + ++ L ++ R D ++ ++ ++ +G +R ++
Sbjct: 2315 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2374
Query: 1106 DRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDD-DRLSRRADDDRFPRRGDDS 1164
+R +R L+ +A+ +R+ R AE R R +D R ++A++ +
Sbjct: 2375 ER--QRQLE------MSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2426
Query: 1165 RPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPE 1224
LV+ + ++ + RE+ ERE ++ ++ + Q + E + +
Sbjct: 2427 ATQEKVTLVQTLEIQRQQSDHDAE--RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2484
Query: 1225 RERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLR 1284
+E+ + + F +D R E+ + + +D+ + + RE R
Sbjct: 2485 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ----R 2540
Query: 1285 ERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRD 1344
+++ + +R R + R RK + +++ + RR L+ + +R R+
Sbjct: 2541 QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2600
Query: 1345 R 1345
+
Sbjct: 2601 Q 2601
Score = 75.1 bits (183), Expect = 4e-13
Identities = 81/392 (20%), Positives = 181/392 (46%), Gaps = 47/392 (11%)
Query: 480 LQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKP 539
LQ + + + L+ A +E A L+ + E + Q +L + ++ ++
Sbjct: 2270 LQEEAEKMKQVAEEAARLSVAAQEAA----RLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2325
Query: 540 AHILQ-EKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQRE 598
A L+ E E Q A + R + + +Q EE + +L +R+++ E
Sbjct: 2326 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2385
Query: 599 AELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDI 658
AE K+R AE R + A+E + +R ++ E+I +K R L +K L + ++I
Sbjct: 2386 AERLKLRVAEMSRAQARAEE-DAQRFRKQAEEIGEKLHRTELATQEKVTL----VQTLEI 2440
Query: 659 EDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQR 718
+ + + + + +LE+EK++LQ+ AK L+
Sbjct: 2441 QRQQSDHDAERLREAIAELEREKEKLQQE-------------AKLLQ------------- 2474
Query: 719 IKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQ 778
+K ++ Q+E+ + Q ++ L K+ + + R+ F+ + KA + ++++++ +
Sbjct: 2475 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ----RERFIEQEKAKLEQLFQDEVAK 2530
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKRE 838
++ E++ ++++ +E +R+ E+ Q AEE + +++EE ++ E+ +R+
Sbjct: 2531 AQQLREEQQR----QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2586
Query: 839 EE--LREYQERVK-KLEEVERKKRQRELEIEE 867
+E L E +R++ +L+ +E + R EE
Sbjct: 2587 QEELLAEENQRLREQLQLLEEQHRAALAHSEE 2618
Score = 65.9 bits (159), Expect = 3e-10
Identities = 188/946 (19%), Positives = 362/946 (38%), Gaps = 135/946 (14%)
Query: 491 LSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQH 550
LS ++ A E +P P L+S E +L + S+ A LE +K ++ +
Sbjct: 1047 LSAEAEKVLALPEPSPAAPTLRS-ELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGA 1105
Query: 551 QLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEE- 609
+ + A+ + KE Q + A +E K L+ L Q E ++ +A ++R A+E
Sbjct: 1106 EEVLRAH-EEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ-PTFDALRDELRGAQEV 1163
Query: 610 -ERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668
ERL+Q ER+ ++ + RER+ Q+ + A D+ +LE+L
Sbjct: 1164 GERLQQRHGERD----------VEVERWRERVAQLLERWQAVLAQTDVRQRELEQL---- 1209
Query: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQ 728
+Q+ + L L++ + R ++++ +PL S Q +++ EQ
Sbjct: 1210 --GRQLRYYRESADPLGAWLQDARR------RQEQIQAMPLADS----QAVREQLRQEQA 1257
Query: 729 EEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVY----EEKLKQFEERLA 784
E I + E+ + ++D +L ++ KA + V + K++ E +
Sbjct: 1258 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1317
Query: 785 EE------RHNRL------------EERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
+E ++ L E +R +EER R +E E E + K+R
Sbjct: 1318 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR 1377
Query: 827 E--ERERAERAKREEELREYQERVKK-------------------LEEVERKKRQRELEI 865
+ E +A+ E E +E Q+R+++ EE+++ ++ E EI
Sbjct: 1378 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1437
Query: 866 EERER----------RREEERRLGDSSLSRKDSRWGDRDSE--GTWRKGPEADSEWRRGP 913
+ + R R EEE R+ L + + G + E + EA+++ R+
Sbjct: 1438 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1497
Query: 914 PEKEWRRGEGRDEDRSHRRDE-ERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGP 972
E E R + +DE + R+ E E R+ + + R +R + R
Sbjct: 1498 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA--------REKQRALQALEELRLQA 1549
Query: 973 EEDRFSRRGADDDRPSWRNTDDDRPPRRI-ADEDRGNWRHADDDRPPRRGLDEDRGSWRT 1031
EE R A+ +R + R A+ A+ R L E+ +
Sbjct: 1550 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1609
Query: 1032 ADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRR 1091
E+ R + R A+ E W+ ++ R ++ ++ + ++
Sbjct: 1610 LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1669
Query: 1092 GMDDDR-GPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSR 1150
+ +R RRG +++ R+ R AE + R + + +
Sbjct: 1670 KEEAEREARRRGKAEEQAVRQ------------------RELAEQELEKQRQLAEGTAQQ 1711
Query: 1151 R--ADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKE 1208
R A+ + R + + R L++ R + +A + R+ +E + E E
Sbjct: 1712 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT--QKRQELEAELAKVRAEME 1769
Query: 1209 RDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDR 1268
++ R E + E+ ++R RFR +E R AEE+ R +
Sbjct: 1770 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLA----- 1824
Query: 1269 DRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPR 1328
+ D R+ + R L E+ + R L++E E + A++ + R+ E + +
Sbjct: 1825 EEDAARQRAEAERVLAEKLAAIGEATR----LKTEAEIALKEKEAENERLRRLAEDEAFQ 1880
Query: 1329 RVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDE 1374
R R E+ + + E+ A R D E L R K ++
Sbjct: 1881 R------RRLEEQAAQHKADIEERLAQLRKASDSE-LERQKGLVED 1919
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 89.7 bits (221), Expect = 2e-17
Identities = 146/687 (21%), Positives = 271/687 (39%), Gaps = 81/687 (11%)
Query: 437 LRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSD 496
LR +++ ++ + L A + +R + +A H + + + ++ L
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEA--HAQAKAQAEREAKELQQRMQ 1398
Query: 497 LNYATREDAPIGPHLQSMPSEQIRNQLTAMSS--VLAKAL-------------EVIKPAH 541
RE+A + Q ++ QL S + AKA E I+
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1458
Query: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL 601
+ E E+ + L+ R + A+++ +E ERL +Q E + Q E EL
Sbjct: 1459 LQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRR-QVQDESQRKRQAEVEL 1517
Query: 602 QKVRKAEEERLRQEAKEREK-ERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
KAE E R++ + + E + + E+ +++ + +E+ ++ ++ + + +
Sbjct: 1518 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAE 1577
Query: 661 LEELDPDFIMAKQVEQLEKEKKE-------LQERLKNQEKKIDYFERAKRLEEIPLIKSA 713
L+ F A++ QLE+ +E L+E + + ++ ERA+ E L +
Sbjct: 1578 LQSKRASF--AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ 1635
Query: 714 YEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRM--------LEDRDLFVMRLK 765
+ + L ++ ++ + Q E EK E R +R + R+L L+
Sbjct: 1636 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1695
Query: 766 AARQ---SVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAE--E 820
RQ +++L +E + E++RQ EE RE Q+R E
Sbjct: 1696 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Query: 821 QMLKEREERE--RAERAKREEELREYQERVKKLEEVE-------------------RKKR 859
++ K R E E A +A+ EEE R E+ K+ E E KR
Sbjct: 1756 ELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKR 1815
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
QR+L E+ R+R E R+ L+ K + G+ R EA+ + E E
Sbjct: 1816 QRQLAEEDAARQRAEAERV----LAEKLAAIGE-----ATRLKTEAEIALKEKEAENERL 1866
Query: 920 RGEGRDEDRSHRR-DEERPRRLGDDEDREPSLR--PDDDRVPRRGMDDDRGPRRGPEEDR 976
R DE RR +E+ + D E+R LR D + ++G+ +D +R E+
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1926
Query: 977 FSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDR 1036
A ++ + + + RI R + + L+ R A+E+R
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-----QAELEAARQRQLAAEEER 1981
Query: 1037 GPRRGMDDDRGPRRGGADDERSSWRNA 1063
RR ++R + A++E + R A
Sbjct: 1982 --RRREAEERVQKSLAAEEEAARQRKA 2006
Score = 88.2 bits (217), Expect = 5e-17
Identities = 208/1021 (20%), Positives = 394/1021 (38%), Gaps = 135/1021 (13%)
Query: 415 REQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLER----A 470
R + E E EL+++ QL+ N LRL Q ++ Q ++ + +A + R A
Sbjct: 1622 RAREEAERELERW--QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1679
Query: 471 IVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVL 530
A R +L + R L+ G+ E I ++ EQ R L + L
Sbjct: 1680 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1739
Query: 531 AKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQRE 590
+ + A Q+++E + A L R E + +LA + EE + QR
Sbjct: 1740 QR-----EAAAATQKRQE-----LEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQR- 1788
Query: 591 KEELEQREAELQKVRKAEEE--RLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEL 648
EAE + R+ EE RLR A+E +++R L E + +++ ER+ K +
Sbjct: 1789 ------LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1842
Query: 649 G-----------AKAFKDIDIEDLEELDPD--FIMAKQVEQLEKEKKELQERLKNQEKKI 695
G A K+ + E L L D F + EQ + K +++ERL K
Sbjct: 1843 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1902
Query: 696 DY-FERAKRL------------EEIPLIKSAYEEQRIKDMDLW----------------- 725
D ER K L EEI +K+++E+ +L
Sbjct: 1903 DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1962
Query: 726 EQQEEERITTMQL---EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEER 782
EQ E E QL E + E + R+ + L + + KAA + V K K E R
Sbjct: 1963 EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEAR 2022
Query: 783 LAEERHNRLEER----------KRQRKEERRITY-YREKEEEEQRRAEEQMLKEREERER 831
ER + R KR + EE+ + ++KE+E Q+ +++ + R
Sbjct: 2023 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2082
Query: 832 AERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWG 891
AE A+R EE E + Q E E + R+ EE RL S+ + +R
Sbjct: 2083 AEAARR------------AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2130
Query: 892 DRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRD-EDRSHRRDEERPRRLG--------- 941
+ + RK E ++ R + R+ + D E H++ E+ R
Sbjct: 2131 AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2190
Query: 942 -----DDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRN----- 991
++ D + +L ++ + + + R EE+ FS R ++ +
Sbjct: 2191 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Query: 992 ------TDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDD 1045
D D R + +E + A++ E + A+ED +R + +
Sbjct: 2251 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 1046 RGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDD 1105
+ A E + + + ++ L ++ R D ++ ++ ++ +G +R ++
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 1106 DRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDD-DRLSRRADDDRFPRRGDDS 1164
+R +R L+ +A+ +R+ R AE R R +D R ++A++ +
Sbjct: 2371 ER--QRQLE------MSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2422
Query: 1165 RPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPE 1224
LV+ + ++ + RE+ ERE ++ ++ + Q + E + +
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAE--RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2480
Query: 1225 RERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLR 1284
+E+ + + F +D R E+ + + +D+ + + RE R
Sbjct: 2481 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ----R 2536
Query: 1285 ERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRD 1344
+++ + +R R + R RK + +++ + RR L+ + +R R+
Sbjct: 2537 QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2596
Query: 1345 R 1345
+
Sbjct: 2597 Q 2597
Score = 75.1 bits (183), Expect = 4e-13
Identities = 81/392 (20%), Positives = 181/392 (46%), Gaps = 47/392 (11%)
Query: 480 LQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKP 539
LQ + + + L+ A +E A L+ + E + Q +L + ++ ++
Sbjct: 2266 LQEEAEKMKQVAEEAARLSVAAQEAA----RLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2321
Query: 540 AHILQ-EKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQRE 598
A L+ E E Q A + R + + +Q EE + +L +R+++ E
Sbjct: 2322 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381
Query: 599 AELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDI 658
AE K+R AE R + A+E + +R ++ E+I +K R L +K L + ++I
Sbjct: 2382 AERLKLRVAEMSRAQARAEE-DAQRFRKQAEEIGEKLHRTELATQEKVTL----VQTLEI 2436
Query: 659 EDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQR 718
+ + + + + +LE+EK++LQ+ AK L+
Sbjct: 2437 QRQQSDHDAERLREAIAELEREKEKLQQE-------------AKLLQ------------- 2470
Query: 719 IKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQ 778
+K ++ Q+E+ + Q ++ L K+ + + R+ F+ + KA + ++++++ +
Sbjct: 2471 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ----RERFIEQEKAKLEQLFQDEVAK 2526
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKRE 838
++ E++ ++++ +E +R+ E+ Q AEE + +++EE ++ E+ +R+
Sbjct: 2527 AQQLREEQQR----QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Query: 839 EE--LREYQERVK-KLEEVERKKRQRELEIEE 867
+E L E +R++ +L+ +E + R EE
Sbjct: 2583 QEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Score = 65.9 bits (159), Expect = 3e-10
Identities = 188/946 (19%), Positives = 362/946 (38%), Gaps = 135/946 (14%)
Query: 491 LSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQH 550
LS ++ A E +P P L+S E +L + S+ A LE +K ++ +
Sbjct: 1043 LSAEAEKVLALPEPSPAAPTLRS-ELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGA 1101
Query: 551 QLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEE- 609
+ + A+ + KE Q + A +E K L+ L Q E ++ +A ++R A+E
Sbjct: 1102 EEVLRAH-EEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ-PTFDALRDELRGAQEV 1159
Query: 610 -ERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668
ERL+Q ER+ ++ + RER+ Q+ + A D+ +LE+L
Sbjct: 1160 GERLQQRHGERD----------VEVERWRERVAQLLERWQAVLAQTDVRQRELEQL---- 1205
Query: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQ 728
+Q+ + L L++ + R ++++ +PL S Q +++ EQ
Sbjct: 1206 --GRQLRYYRESADPLGAWLQDARR------RQEQIQAMPLADS----QAVREQLRQEQA 1253
Query: 729 EEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVY----EEKLKQFEERLA 784
E I + E+ + ++D +L ++ KA + V + K++ E +
Sbjct: 1254 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1313
Query: 785 EE------RHNRL------------EERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
+E ++ L E +R +EER R +E E E + K+R
Sbjct: 1314 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR 1373
Query: 827 E--ERERAERAKREEELREYQERVKK-------------------LEEVERKKRQRELEI 865
+ E +A+ E E +E Q+R+++ EE+++ ++ E EI
Sbjct: 1374 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1433
Query: 866 EERER----------RREEERRLGDSSLSRKDSRWGDRDSE--GTWRKGPEADSEWRRGP 913
+ + R R EEE R+ L + + G + E + EA+++ R+
Sbjct: 1434 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1493
Query: 914 PEKEWRRGEGRDEDRSHRRDE-ERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGP 972
E E R + +DE + R+ E E R+ + + R +R + R
Sbjct: 1494 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA--------REKQRALQALEELRLQA 1545
Query: 973 EEDRFSRRGADDDRPSWRNTDDDRPPRRI-ADEDRGNWRHADDDRPPRRGLDEDRGSWRT 1031
EE R A+ +R + R A+ A+ R L E+ +
Sbjct: 1546 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1605
Query: 1032 ADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRR 1091
E+ R + R A+ E W+ ++ R ++ ++ + ++
Sbjct: 1606 LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1665
Query: 1092 GMDDDR-GPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSR 1150
+ +R RRG +++ R+ R AE + R + + +
Sbjct: 1666 KEEAEREARRRGKAEEQAVRQ------------------RELAEQELEKQRQLAEGTAQQ 1707
Query: 1151 R--ADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKE 1208
R A+ + R + + R L++ R + +A + R+ +E + E E
Sbjct: 1708 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT--QKRQELEAELAKVRAEME 1765
Query: 1209 RDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDR 1268
++ R E + E+ ++R RFR +E R AEE+ R +
Sbjct: 1766 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLA----- 1820
Query: 1269 DRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPR 1328
+ D R+ + R L E+ + R L++E E + A++ + R+ E + +
Sbjct: 1821 EEDAARQRAEAERVLAEKLAAIGEATR----LKTEAEIALKEKEAENERLRRLAEDEAFQ 1876
Query: 1329 RVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDE 1374
R R E+ + + E+ A R D E L R K ++
Sbjct: 1877 R------RRLEEQAAQHKADIEERLAQLRKASDSE-LERQKGLVED 1915
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 89.7 bits (221), Expect = 2e-17
Identities = 146/687 (21%), Positives = 271/687 (39%), Gaps = 81/687 (11%)
Query: 437 LRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSD 496
LR +++ ++ + L A + +R + +A H + + + ++ L
Sbjct: 1309 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEA--HAQAKAQAEREAKELQQRMQ 1366
Query: 497 LNYATREDAPIGPHLQSMPSEQIRNQLTAMSS--VLAKAL-------------EVIKPAH 541
RE+A + Q ++ QL S + AKA E I+
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVR 1426
Query: 542 ILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAEL 601
+ E E+ + L+ R + A+++ +E ERL +Q E + Q E EL
Sbjct: 1427 LQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRR-QVQDESQRKRQAEVEL 1485
Query: 602 QKVRKAEEERLRQEAKEREK-ERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIED 660
KAE E R++ + + E + + E+ +++ + +E+ ++ ++ + + +
Sbjct: 1486 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAE 1545
Query: 661 LEELDPDFIMAKQVEQLEKEKKE-------LQERLKNQEKKIDYFERAKRLEEIPLIKSA 713
L+ F A++ QLE+ +E L+E + + ++ ERA+ E L +
Sbjct: 1546 LQSKRASF--AEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQ 1603
Query: 714 YEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRM--------LEDRDLFVMRLK 765
+ + L ++ ++ + Q E EK E R +R + R+L L+
Sbjct: 1604 LKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELE 1663
Query: 766 AARQ---SVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAE--E 820
RQ +++L +E + E++RQ EE RE Q+R E
Sbjct: 1664 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1723
Query: 821 QMLKEREERE--RAERAKREEELREYQERVKKLEEVE-------------------RKKR 859
++ K R E E A +A+ EEE R E+ K+ E E KR
Sbjct: 1724 ELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKR 1783
Query: 860 QRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWR 919
QR+L E+ R+R E R+ L+ K + G+ R EA+ + E E
Sbjct: 1784 QRQLAEEDAARQRAEAERV----LAEKLAAIGE-----ATRLKTEAEIALKEKEAENERL 1834
Query: 920 RGEGRDEDRSHRR-DEERPRRLGDDEDREPSLR--PDDDRVPRRGMDDDRGPRRGPEEDR 976
R DE RR +E+ + D E+R LR D + ++G+ +D +R E+
Sbjct: 1835 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1894
Query: 977 FSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDR 1036
A ++ + + + RI R + + L+ R A+E+R
Sbjct: 1895 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKE-----QAELEAARQRQLAAEEER 1949
Query: 1037 GPRRGMDDDRGPRRGGADDERSSWRNA 1063
RR ++R + A++E + R A
Sbjct: 1950 --RRREAEERVQKSLAAEEEAARQRKA 1974
Score = 88.2 bits (217), Expect = 5e-17
Identities = 208/1021 (20%), Positives = 394/1021 (38%), Gaps = 135/1021 (13%)
Query: 415 REQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSIEFSRLTSLVPFVDAFQLER----A 470
R + E E EL+++ QL+ N LRL Q ++ Q ++ + +A + R A
Sbjct: 1590 RAREEAERELERW--QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKA 1647
Query: 471 IVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVL 530
A R +L + R L+ G+ E I ++ EQ R L + L
Sbjct: 1648 EEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARL 1707
Query: 531 AKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQRE 590
+ + A Q+++E + A L R E + +LA + EE + QR
Sbjct: 1708 QR-----EAAAATQKRQE-----LEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQR- 1756
Query: 591 KEELEQREAELQKVRKAEEE--RLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTEL 648
EAE + R+ EE RLR A+E +++R L E + +++ ER+ K +
Sbjct: 1757 ------LEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAI 1810
Query: 649 G-----------AKAFKDIDIEDLEELDPD--FIMAKQVEQLEKEKKELQERLKNQEKKI 695
G A K+ + E L L D F + EQ + K +++ERL K
Sbjct: 1811 GEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKAS 1870
Query: 696 DY-FERAKRL------------EEIPLIKSAYEEQRIKDMDLW----------------- 725
D ER K L EEI +K+++E+ +L
Sbjct: 1871 DSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSK 1930
Query: 726 EQQEEERITTMQL---EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEER 782
EQ E E QL E + E + R+ + L + + KAA + V K K E R
Sbjct: 1931 EQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEAR 1990
Query: 783 LAEERHNRLEER----------KRQRKEERRITY-YREKEEEEQRRAEEQMLKEREERER 831
ER + R KR + EE+ + ++KE+E Q+ +++ + R
Sbjct: 1991 RLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGE 2050
Query: 832 AERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWG 891
AE A+R EE E + Q E E + R+ EE RL S+ + +R
Sbjct: 2051 AEAARR------------AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQ 2098
Query: 892 DRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRD-EDRSHRRDEERPRRLG--------- 941
+ + RK E ++ R + R+ + D E H++ E+ R
Sbjct: 2099 AQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTT 2158
Query: 942 -----DDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRN----- 991
++ D + +L ++ + + + R EE+ FS R ++ +
Sbjct: 2159 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2218
Query: 992 ------TDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDD 1045
D D R + +E + A++ E + A+ED +R + +
Sbjct: 2219 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2278
Query: 1046 RGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDD 1105
+ A E + + + ++ L ++ R D ++ ++ ++ +G +R ++
Sbjct: 2279 MLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2338
Query: 1106 DRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDD-DRLSRRADDDRFPRRGDDS 1164
+R +R L+ +A+ +R+ R AE R R +D R ++A++ +
Sbjct: 2339 ER--QRQLE------MSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2390
Query: 1165 RPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPE 1224
LV+ + ++ + RE+ ERE ++ ++ + Q + E + +
Sbjct: 2391 ATQEKVTLVQTLEIQRQQSDHDAE--RLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQ 2448
Query: 1225 RERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLR 1284
+E+ + + F +D R E+ + + +D+ + + RE R
Sbjct: 2449 QEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQ----R 2504
Query: 1285 ERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRD 1344
+++ + +R R + R RK + +++ + RR L+ + +R R+
Sbjct: 2505 QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLRE 2564
Query: 1345 R 1345
+
Sbjct: 2565 Q 2565
Score = 75.1 bits (183), Expect = 4e-13
Identities = 81/392 (20%), Positives = 181/392 (46%), Gaps = 47/392 (11%)
Query: 480 LQVRIDHTSRTLSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKP 539
LQ + + + L+ A +E A L+ + E + Q +L + ++ ++
Sbjct: 2234 LQEEAEKMKQVAEEAARLSVAAQEAA----RLRQLAEEDLAQQRALAEKMLKEKMQAVQE 2289
Query: 540 AHILQ-EKEEQHQLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQRE 598
A L+ E E Q A + R + + +Q EE + +L +R+++ E
Sbjct: 2290 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2349
Query: 599 AELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDI 658
AE K+R AE R + A+E + +R ++ E+I +K R L +K L + ++I
Sbjct: 2350 AERLKLRVAEMSRAQARAEE-DAQRFRKQAEEIGEKLHRTELATQEKVTL----VQTLEI 2404
Query: 659 EDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQR 718
+ + + + + +LE+EK++LQ+ AK L+
Sbjct: 2405 QRQQSDHDAERLREAIAELEREKEKLQQE-------------AKLLQ------------- 2438
Query: 719 IKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQ 778
+K ++ Q+E+ + Q ++ L K+ + + R+ F+ + KA + ++++++ +
Sbjct: 2439 LKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQ----RERFIEQEKAKLEQLFQDEVAK 2494
Query: 779 FEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKRE 838
++ E++ ++++ +E +R+ E+ Q AEE + +++EE ++ E+ +R+
Sbjct: 2495 AQQLREEQQR----QQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2550
Query: 839 EE--LREYQERVK-KLEEVERKKRQRELEIEE 867
+E L E +R++ +L+ +E + R EE
Sbjct: 2551 QEELLAEENQRLREQLQLLEEQHRAALAHSEE 2582
Score = 65.9 bits (159), Expect = 3e-10
Identities = 188/946 (19%), Positives = 362/946 (38%), Gaps = 135/946 (14%)
Query: 491 LSFGSDLNYATREDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQH 550
LS ++ A E +P P L+S E +L + S+ A LE +K ++ +
Sbjct: 1011 LSAEAEKVLALPEPSPAAPTLRS-ELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGA 1069
Query: 551 QLAVTAYLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEE- 609
+ + A+ + KE Q + A +E K L+ L Q E ++ +A ++R A+E
Sbjct: 1070 EEVLRAH-EEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQ-PTFDALRDELRGAQEV 1127
Query: 610 -ERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668
ERL+Q ER+ ++ + RER+ Q+ + A D+ +LE+L
Sbjct: 1128 GERLQQRHGERD----------VEVERWRERVAQLLERWQAVLAQTDVRQRELEQL---- 1173
Query: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQ 728
+Q+ + L L++ + R ++++ +PL S Q +++ EQ
Sbjct: 1174 --GRQLRYYRESADPLGAWLQDARR------RQEQIQAMPLADS----QAVREQLRQEQA 1221
Query: 729 EEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVY----EEKLKQFEERLA 784
E I + E+ + ++D +L ++ KA + V + K++ E +
Sbjct: 1222 LLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVI 1281
Query: 785 EE------RHNRL------------EERKRQRKEERRITYYREKEEEEQRRAEEQMLKER 826
+E ++ L E +R +EER R +E E E + K+R
Sbjct: 1282 QEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQR 1341
Query: 827 E--ERERAERAKREEELREYQERVKK-------------------LEEVERKKRQRELEI 865
+ E +A+ E E +E Q+R+++ EE+++ ++ E EI
Sbjct: 1342 QLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEI 1401
Query: 866 EERER----------RREEERRLGDSSLSRKDSRWGDRDSE--GTWRKGPEADSEWRRGP 913
+ + R R EEE R+ L + + G + E + EA+++ R+
Sbjct: 1402 QAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQ 1461
Query: 914 PEKEWRRGEGRDEDRSHRRDE-ERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGP 972
E E R + +DE + R+ E E R+ + + R +R + R
Sbjct: 1462 EEAERLRRQVQDESQRKRQAEVELASRVKAEAEAA--------REKQRALQALEELRLQA 1513
Query: 973 EEDRFSRRGADDDRPSWRNTDDDRPPRRI-ADEDRGNWRHADDDRPPRRGLDEDRGSWRT 1031
EE R A+ +R + R A+ A+ R L E+ +
Sbjct: 1514 EEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQ 1573
Query: 1032 ADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRR 1091
E+ R + R A+ E W+ ++ R ++ ++ + ++
Sbjct: 1574 LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQ 1633
Query: 1092 GMDDDR-GPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSR 1150
+ +R RRG +++ R+ R AE + R + + +
Sbjct: 1634 KEEAEREARRRGKAEEQAVRQ------------------RELAEQELEKQRQLAEGTAQQ 1675
Query: 1151 R--ADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKE 1208
R A+ + R + + R L++ R + +A + R+ +E + E E
Sbjct: 1676 RLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT--QKRQELEAELAKVRAEME 1733
Query: 1209 RDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDR 1268
++ R E + E+ ++R RFR +E R AEE+ R +
Sbjct: 1734 VLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLA----- 1788
Query: 1269 DRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPR 1328
+ D R+ + R L E+ + R L++E E + A++ + R+ E + +
Sbjct: 1789 EEDAARQRAEAERVLAEKLAAIGEATR----LKTEAEIALKEKEAENERLRRLAEDEAFQ 1844
Query: 1329 RVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDE 1374
R R E+ + + E+ A R D E L R K ++
Sbjct: 1845 R------RRLEEQAAQHKADIEERLAQLRKASDSE-LERQKGLVED 1883
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,992,280
Number of Sequences: 37866
Number of extensions: 3363410
Number of successful extensions: 90217
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 996
Number of HSP's successfully gapped in prelim test: 1548
Number of HSP's that attempted gapping in prelim test: 15973
Number of HSP's gapped (non-prelim): 24861
length of query: 1382
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1267
effective length of database: 13,892,928
effective search space: 17602339776
effective search space used: 17602339776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.