Guide to the Human Genome
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Name: HBEGF Sequence: fasta or formatted (208aa) NCBI GI: 4503413
Description:

heparin-binding EGF-like growth factor

Referenced in:

Epidermal Growth Factor

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.3         11           2
 C cysteine            3.4          7           1
 D aspartate           4.8         10           1
 E glutamate           5.8         12           2
 F phenylalanine       1.4          3           1
 G glycine             8.7         18           3
 H histidine           3.8          8           1
 I isoleucine          1.9          4           1
 K lysine              8.7         18           3
 L leucine            15.4         32           2
 M methionine          1.4          3           1
 N asparagine          2.4          5           1
 P proline             5.3         11           2
 Q glutamine           1.4          3           1
 R arginine            7.7         16           2
 S serine              5.8         12           2
 T threonine           4.8         10           2
 V valine              8.7         18           2
 W tryptophan          0.0          0           0
 Y tyrosine            3.4          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   heparin-binding EGF-like growth factor 
AREG                  0.143   amphiregulin preproprotein 
AREGB                 0.143   PREDICTED: amphiregulin B 
BTC                   0.070   betacellulin 
TGFA                  0.068   transforming growth factor, alpha isoform 2 
TGFA                  0.068   transforming growth factor, alpha isoform 1 
TMEFF2                0.063   transmembrane protein with EGF-like and two follista...
TMEFF1                0.060   transmembrane protein with EGF-like and two follista...
EPGN                  0.053   epithelial mitogen 
NRG1                  0.048   neuregulin 1 isoform ndf43c 
NRG1                  0.048   neuregulin 1 isoform HRG-alpha 
NRG1                  0.048   neuregulin 1 isoform ndf43 
EREG                  0.043   epiregulin preproprotein 
EGF                   0.040   epidermal growth factor (beta-urogastrone) 
NRG4                  0.035   neuregulin 4 
NRG2                  0.030   neuregulin 2 isoform 2 
NRG2                  0.030   neuregulin 2 isoform 4 
SLIT3                 0.028   slit homolog 3 
LRP2                  0.028   low density lipoprotein-related protein 2 
NOTCH2                0.023   notch 2 preproprotein 
NRG2                  0.023   neuregulin 2 isoform 1 
PVRL4                 0.020   poliovirus receptor-related 4 
NRG2                  0.020   neuregulin 2 isoform 3 
NOTCH3                0.020   Notch homolog 3 
PEAR1                 0.020   platelet endothelial aggregation receptor 1 
SLIT1                 0.020   slit homolog 1 
MEGF11                0.020   multiple EGF-like-domains 11 
DNER                  0.020   delta-notch-like EGF repeat-containing transmembran...
NPNT                  0.018   nephronectin 
NOTCH1                0.018   notch1 preproprotein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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