Guide to the Human Genome
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Name: AREG Sequence: fasta or formatted (252aa) NCBI GI: 4502199
Description:

amphiregulin preproprotein

Referenced in:

Epidermal Growth Factor

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.5         19           2
 C cysteine            2.4          6           1
 D aspartate           4.4         11           2
 E glutamate           9.5         24           2
 F phenylalanine       2.4          6           1
 G glycine             6.7         17           2
 H histidine           2.4          6           1
 I isoleucine          4.8         12           1
 K lysine              8.3         21           3
 L leucine             5.6         14           2
 M methionine          2.4          6           1
 N asparagine          4.8         12           1
 P proline             5.6         14           2
 Q glutamine           3.6          9           2
 R arginine            5.6         14           2
 S serine             10.7         27           3
 T threonine           3.2          8           1
 V valine              6.3         16           2
 W tryptophan          0.0          0           0
 Y tyrosine            4.0         10           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   amphiregulin preproprotein 
AREGB                 1.000   PREDICTED: amphiregulin B 
HBEGF                 0.118   heparin-binding EGF-like growth factor 
TMEFF1                0.060   transmembrane protein with EGF-like and two follista...
TMEFF2                0.056   transmembrane protein with EGF-like and two follista...
EREG                  0.041   epiregulin preproprotein 
NRG2                  0.041   neuregulin 2 isoform 2 
NRG2                  0.039   neuregulin 2 isoform 1 
TGFA                  0.039   transforming growth factor, alpha isoform 2 
TGFA                  0.039   transforming growth factor, alpha isoform 1 
NRG2                  0.039   neuregulin 2 isoform 3 
BTC                   0.037   betacellulin 
EGF                   0.035   epidermal growth factor (beta-urogastrone) 
NRG2                  0.033   neuregulin 2 isoform 4 
EPGN                  0.033   epithelial mitogen 
PHIP                  0.031   pleckstrin homology domain interacting protein [Homo...
IWS1                  0.029   IWS1 homolog 
NRG4                  0.029   neuregulin 4 
NRG1                  0.027   neuregulin 1 isoform ndf43b 
NRG1                  0.027   neuregulin 1 isoform HRG-beta2b 
NRG1                  0.027   neuregulin 1 isoform HRG-beta2 
NRG1                  0.025   neuregulin 1 isoform SMDF 
VEGFA                 0.021   vascular endothelial growth factor A isoform c precu...
MTUS1                 0.021   mitochondrial tumor suppressor 1 isoform 1 
MTUS1                 0.021   mitochondrial tumor suppressor 1 isoform 2 
NRG1                  0.021   neuregulin 1 isoform HRG-beta1d 
NRG1                  0.021   neuregulin 1 isoform HRG-beta1b 
NRG1                  0.021   neuregulin 1 isoform ndf43c 
NRG1                  0.021   neuregulin 1 isoform HRG-beta1c 
NRG1                  0.021   neuregulin 1 isoform HRG-beta1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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