Guide to the Human Genome
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Name: EREG Sequence: fasta or formatted (169aa) NCBI GI: 4557567
Description:

epiregulin preproprotein

Referenced in:

Epidermal Growth Factor

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.1          7           1
 C cysteine            6.5         11           1
 D aspartate           3.0          5           1
 E glutamate           5.9         10           1
 F phenylalanine       3.0          5           2
 G glycine             5.9         10           1
 H histidine           2.4          4           1
 I isoleucine          4.7          8           2
 K lysine              3.6          6           2
 L leucine            10.7         18           3
 M methionine          3.0          5           1
 N asparagine          3.0          5           1
 P proline             4.7          8           1
 Q glutamine           4.1          7           1
 R arginine            5.9         10           2
 S serine              7.1         12           2
 T threonine           7.1         12           2
 V valine              9.5         16           2
 W tryptophan          0.6          1           1
 Y tyrosine            5.3          9           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   epiregulin preproprotein 
EGF                   0.095   epidermal growth factor (beta-urogastrone) 
BTC                   0.095   betacellulin 
EPGN                  0.091   epithelial mitogen 
TMEFF2                0.088   transmembrane protein with EGF-like and two follista...
NRG2                  0.085   neuregulin 2 isoform 2 
TMEFF1                0.082   transmembrane protein with EGF-like and two follista...
TGFA                  0.079   transforming growth factor, alpha isoform 1 
NRG4                  0.073   neuregulin 4 
TGFA                  0.073   transforming growth factor, alpha isoform 2 
NRG2                  0.073   neuregulin 2 isoform 4 
AREG                  0.061   amphiregulin preproprotein 
AREGB                 0.061   PREDICTED: amphiregulin B 
HBEGF                 0.052   heparin-binding EGF-like growth factor 
LRP1                  0.049   low density lipoprotein-related protein 1 
NRG3                  0.049   neuregulin 3 
NRG2                  0.049   neuregulin 2 isoform 1 
NRG1                  0.043   neuregulin 1 isoform ndf43b 
NRG1                  0.043   neuregulin 1 isoform HRG-beta2b 
NRG1                  0.043   neuregulin 1 isoform HRG-beta2 
LRP2                  0.043   low density lipoprotein-related protein 2 
NRG1                  0.040   neuregulin 1 isoform ndf43c 
NRG1                  0.040   neuregulin 1 isoform HRG-alpha 
NRG1                  0.040   neuregulin 1 isoform ndf43 
NRG2                  0.040   neuregulin 2 isoform 3 
CSPG5                 0.037   chondroitin sulfate proteoglycan 5 (neuroglycan C) ...
NRG1                  0.037   neuregulin 1 isoform HRG-beta1d 
NRG1                  0.037   neuregulin 1 isoform HRG-beta1b 
NRG1                  0.037   neuregulin 1 isoform HRG-beta1c 
NRG1                  0.037   neuregulin 1 isoform HRG-beta1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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