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Search of human proteins with 4503293
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo
sapiens]
(1041 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 2056 0.0
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 762 0.0
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 688 0.0
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 647 0.0
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 593 e-169
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 547 e-155
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 477 e-134
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 364 e-100
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 355 9e-98
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 349 9e-96
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 291 2e-78
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 280 7e-75
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 280 7e-75
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 258 2e-68
gi|166851804 tudor domain containing 9 [Homo sapiens] 239 1e-62
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 211 4e-54
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 196 1e-49
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 194 4e-49
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 179 9e-45
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 167 6e-41
gi|38505213 YTH domain containing 2 [Homo sapiens] 159 1e-38
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 84 7e-16
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 81 6e-15
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 80 8e-15
gi|148746195 trichohyalin [Homo sapiens] 79 2e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 75 2e-13
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 3e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 72 3e-12
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 72 4e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 72 4e-12
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 2056 bits (5326), Expect = 0.0
Identities = 1041/1041 (100%), Positives = 1041/1041 (100%)
Query: 1 MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPAR 60
MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPAR
Sbjct: 1 MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPAR 60
Query: 61 DFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK 120
DFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK
Sbjct: 61 DFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK 120
Query: 121 KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDA 180
KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDA
Sbjct: 121 KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDA 180
Query: 181 FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKRER 240
FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKRER
Sbjct: 181 FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKRER 240
Query: 241 EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM 300
EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM
Sbjct: 241 EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM 300
Query: 301 PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE 360
PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE
Sbjct: 301 PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE 360
Query: 361 ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLII 420
ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLII
Sbjct: 361 ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLII 420
Query: 421 EGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYS 480
EGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYS
Sbjct: 421 EGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYS 480
Query: 481 IRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVA 540
IRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVA
Sbjct: 481 IRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVA 540
Query: 541 RFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVL 600
RFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVL
Sbjct: 541 RFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVL 600
Query: 601 QIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIF 660
QIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIF
Sbjct: 601 QIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIF 660
Query: 661 QPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN 720
QPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN
Sbjct: 661 QPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASAN 720
Query: 721 QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDF 780
QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDF
Sbjct: 721 QRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDF 780
Query: 781 LDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI 840
LDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI
Sbjct: 781 LDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEI 840
Query: 841 LTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCE 900
LTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCE
Sbjct: 841 LTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCE 900
Query: 901 NFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYR 960
NFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYR
Sbjct: 901 NFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYR 960
Query: 961 TVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE 1020
TVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE
Sbjct: 961 TVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE 1020
Query: 1021 LEDPHAKKMPKKIGKTREELG 1041
LEDPHAKKMPKKIGKTREELG
Sbjct: 1021 LEDPHAKKMPKKIGKTREELG 1041
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 762 bits (1967), Expect = 0.0
Identities = 368/650 (56%), Positives = 492/650 (75%), Gaps = 12/650 (1%)
Query: 391 SIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIAC 450
SI R SLP++ +E+L+ A+ ++Q+LI+ GETGSGKTTQI QYL E GYT++G KI C
Sbjct: 557 SILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRG-KIGC 615
Query: 451 TQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPD 510
TQPRRVAAMSVA RV+ E G LG EVGY+IRFEDCTS TV++YMTDGMLLRE L +PD
Sbjct: 616 TQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPD 675
Query: 511 LASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVF 570
L Y+++M+DEAHERT+HTD+LFGL+K + R ++K++V SAT+D +FS +F +AP+F
Sbjct: 676 LTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIF 735
Query: 571 RIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQD 630
IPGR +PV+I YTK PE DYL+A +++V+QIH+T+PPGDILVFLTGQEEI+ ACE+L +
Sbjct: 736 TIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYE 795
Query: 631 PCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVL 690
+ LG + EL++LP+Y+ LPS+MQ RIF P PPG+RKVV+ATNIAETS TI+GI YV+
Sbjct: 796 RMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVV 855
Query: 691 DPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEET 750
DPGF KQK YN +TG++ L VTP S+A A QRAGRAGR GKC+RLYT AY+ E+ T
Sbjct: 856 DPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTT 915
Query: 751 TVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGALNHLGELTT 810
VPEIQRT+L + VL LK++GI+DL+ FDF+D PP ETL+ +EQLY LGAL+ G LT
Sbjct: 916 NVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTR 975
Query: 811 SGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVN 870
GR+MAE P++PML KM++ S CSEE+LT+ +MLSV N +FYRPKDK AD +
Sbjct: 976 LGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQN-VFYRPKDKQALADQKKAK 1034
Query: 871 FFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARDVREQLEGLLERVEVGLS 930
F GDHL LL VY W + +S+ WC ENF+Q RS+RRA+D+R+Q+ G+++R ++ +
Sbjct: 1035 FHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVV 1094
Query: 931 SCQGDYIRVRKAITAGYFYHTARL-TRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHEL 989
SC +RV+KAI +G+F + A+ + GYRT+ QQ V+IHP+S+LF +QP W++YHEL
Sbjct: 1095 SCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHEL 1154
Query: 990 VLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREE 1039
VLTTKE+MR+V I+ WL+E AP ++K + P K+ K +++
Sbjct: 1155 VLTTKEYMREVTTIDPRWLVEFAPAFFKVSD---------PTKLSKQKKQ 1195
Score = 38.5 bits (88), Expect = 0.033
Identities = 52/254 (20%), Positives = 104/254 (40%), Gaps = 30/254 (11%)
Query: 14 ELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRK 73
EL + LG++++ +A+F+I A++ T+ + F L + + LRL +
Sbjct: 37 ELDNHLGINDKDLAEFVISLAEKNTTFDTFKASLVKNGA-EFTDSLISNLLRLIQTMRPP 95
Query: 74 AVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKRE 133
A KP+ + + + EK + L + +V R +
Sbjct: 96 A---KPSTSKDPVVKPKTEKEKLKELFPVLCQPDNPSV-----------------RTMLD 135
Query: 134 EEEEEEASEKGKK-----KTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQR 188
E++ + A + K+ + +++ E D ++ +R R +D RD +R R R
Sbjct: 136 EDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRD-RNRDRDRDRERNR 194
Query: 189 DKDRTRNVLERSDKKAYEEAQKRLKMAEEDR-KAMIPELRKKSRREYLAKREREKLEDLE 247
D+D R RS ++ + ++K R ++ P +K R +Y +R ++ D
Sbjct: 195 DRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKY-GERNLDRWRDKH 253
Query: 248 AEL-ADEEFLFGDV 260
+ EE GD+
Sbjct: 254 VDRPPPEEPTIGDI 267
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 688 bits (1776), Expect = 0.0
Identities = 377/894 (42%), Positives = 545/894 (60%), Gaps = 50/894 (5%)
Query: 143 KGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDK 202
+G+++ G + E +WE +R+ +D D + + + + R ++
Sbjct: 294 RGRREEGEEGISFDTEEERQQWEDDQRQADRDWYMMDEGYDEFHNPLAYSSEDYVRRREQ 353
Query: 203 KAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLE---DLEAELADE------ 253
+++ QKR+ R+ + + + L +LE D E + A +
Sbjct: 354 HLHKQKQKRISA---QRRQINEDNERWETNRMLTSGVVHRLEVDEDFEEDNAAKVHLMVH 410
Query: 254 ----EFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPA 309
FL G + ++ + K DLA R + T R H ++ R +
Sbjct: 411 NLVPPFLDGRIVFTKQPEPVIPVKDATSDLAIIARKGSQ------TVRKHREQKERKKA- 463
Query: 310 RAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRAT 369
+ + WE A K G +E + + E+ +++ R
Sbjct: 464 ---------------QHKHWE-----LAGTKLGDIMGVKKEEEPDKAVTEDGKVDY-RTE 502
Query: 370 QLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKT 429
Q D S++ +K+SI R+ LP+F ++ELL I ++ ++I+ GETGSGKT
Sbjct: 503 QKFADHMKRKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKT 562
Query: 430 TQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSE 489
TQ+ QYL E+GYT+ GM I CTQPRRVAAMSVA RV+ EMG LG EVGY+IRFEDCTSE
Sbjct: 563 TQLTQYLHEDGYTDYGM-IGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSE 621
Query: 490 RTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVL 549
T+++YMTDG+LLRE L E DL YS +++DEAHER+L+TD+LFGL+++V R +LK++
Sbjct: 622 NTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLI 681
Query: 550 VASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPG 609
V SATMD +F+ FF + P+F IPGR FPVDI ++K P+ DY+EA V LQ+H++ PG
Sbjct: 682 VTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAPG 741
Query: 610 DILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARK 669
DIL+F+ GQE+IE + + + L L VLPIY+ LPSD+QA+IFQ P G RK
Sbjct: 742 DILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRK 800
Query: 670 VVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRV 729
+VATNIAETS T++GI++V+D G+CK K +NPR GM++L + P S+A+ANQR+GRAGR
Sbjct: 801 CIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRT 860
Query: 730 AAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETL 789
G+CFRLYT AY++EL TTVPEIQRT+L NVVLLLKSLG+ DL+ F F+DPPP + +
Sbjct: 861 GPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNM 920
Query: 790 LLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSV 849
L ++ QL+ LGAL++ G LT++GR M E P+DP LSKM++ S CS EIL + +MLSV
Sbjct: 921 LNSMYQLWILGALDNTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSV 980
Query: 850 NNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMR 909
+IFYRPK + +D R F +P DHL LNVY QW + YS+ WC ++F+ ++MR
Sbjct: 981 -PAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMR 1039
Query: 910 RARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSG-YRTVKQQQTV 968
+ R+VR QL+ ++ + + L+SC D+ VRK I A YF+ A+L G Y ++
Sbjct: 1040 KVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPC 1099
Query: 969 FIHPNSSLFEQ--QPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKE 1020
+HP SSLF P +++YHELV+TTKE+M+ V ++ WL E+ P +Y K+
Sbjct: 1100 HLHPTSSLFGMGYTPDYIVYHELVMTTKEYMQCVTAVDGEWLAELGPMFYSVKQ 1153
Score = 43.5 bits (101), Expect = 0.001
Identities = 53/202 (26%), Positives = 84/202 (41%), Gaps = 21/202 (10%)
Query: 38 TSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSY 97
TS + + RL TD L + + + V + PA R + L+ S
Sbjct: 4 TSEDASIHRLEGTD---LDCQVGGLICKSKSAASEQHVFKAPA---PRPSLLGLDLLASL 57
Query: 98 RLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEK 157
+ E E+ E ++ S K ++ K +K EEE ++A + +K + E
Sbjct: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
Query: 158 PE-----SEDEWERT---ERERLQ------DLEERDAFAERVRQRDKDRTRNVLERSDKK 203
P SE+ WER+ ERER + EE+D E+ R RD DR R+ ER D+
Sbjct: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRDYDRKRDRDER-DRS 176
Query: 204 AYEEAQKRLKMAEEDRKAMIPE 225
+ +R +E + PE
Sbjct: 177 RHSSRSERDGGSERSSRRNEPE 198
Score = 38.9 bits (89), Expect = 0.026
Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 4/154 (2%)
Query: 91 LEKNRSYRLLEDSEESSEETVSRA--GSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKT 148
+ K+R YR S VS S Q++R++R+H +EE++ EK + +
Sbjct: 104 IRKDRHYRSARVETPSHPGGVSEEFWERSRQRERERREHGVYASSKEEKDWKKEKSRDRD 163
Query: 149 GGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEA 208
K+ ++ + R+ER+ + R E R R KD RS + +
Sbjct: 164 YDRKRDRDERDRSRHSSRSERDGGSERSSRRNEPESPRHRPKDAA--TPSRSTWEEEDSG 221
Query: 209 QKRLKMAEEDRKAMIPELRKKSRREYLAKREREK 242
+ ++ + + P R R L+ R+R++
Sbjct: 222 YGSSRRSQWESPSPTPSYRDSERSHRLSTRDRDR 255
Score = 38.5 bits (88), Expect = 0.033
Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 40/181 (22%)
Query: 130 KKREEEEEEEASEKGKKKTGGSK-----QQTEKPESEDEWERTERERLQDLEERDA---- 180
K+RE EE+++ +K K K K + +K E+ ++ + +D R A
Sbjct: 58 KRREREEKDDGEDKKKSKVSSYKDWEESKDDQKDAEEEGGDQAGQNIRKDRHYRSARVET 117
Query: 181 ----------FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKS 230
F ER RQR+++R + + S K+ E+D K ++KS
Sbjct: 118 PSHPGGVSEEFWERSRQRERERREHGVYASSKE------------EKDWK------KEKS 159
Query: 231 R-REYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQ 289
R R+Y KR+R++ + E G E S + + R +D A R+ E+
Sbjct: 160 RDRDYDRKRDRDERDRSRHSSRSER--DGGSERSSRRNEPESPRHRPKDAATPSRSTWEE 217
Query: 290 E 290
E
Sbjct: 218 E 218
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapiens]
Length = 795
Score = 647 bits (1668), Expect = 0.0
Identities = 338/652 (51%), Positives = 451/652 (69%), Gaps = 16/652 (2%)
Query: 396 RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMK--IACTQP 453
R LPV+ +++ + HQ ++ GETGSGKTTQIPQ+ E + G K +ACTQP
Sbjct: 134 RLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQP 193
Query: 454 RRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLAS 513
RRVAAMSVA RVA EM V LG EVGYSIRFEDC+S +T+L+YMTDGMLLRE +++P L
Sbjct: 194 RRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLER 253
Query: 514 YSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIP 573
Y V+++DEAHERTL TDIL G++K+V R R +LKV+V SAT+D +F +FD+ P+ IP
Sbjct: 254 YGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIP 313
Query: 574 GRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPP-GDILVFLTGQEEIEAACEMLQDPC 632
GR PV+IFYT PE DYLEA + +V+QIH+ + GD+L+FLTGQEEI+ AC+ ++
Sbjct: 314 GRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREV 373
Query: 633 RRLGSKIRELLVLPIYANLPSDMQARIFQPTPP----GA--RKVVVATNIAETSPTIEGI 686
LG ++ ++ ++P+Y+ LP Q RIF+P PP GA RKVVV+TNIAETS TI+G+
Sbjct: 374 DDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGV 433
Query: 687 IYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHE 746
++V+DPGF KQK YNPR +ESL VT SKASA QRAGRAGR GKCFRLYT AY+ E
Sbjct: 434 VFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTE 493
Query: 747 LEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGALNHLG 806
+++ T PEI R++LG+VVL LK LGI DL+HFDF+DPP ETL+ LE L L ALN G
Sbjct: 494 MQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDG 553
Query: 807 ELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADN 866
+LT G MAE P+DP L+KM++AS Y+CS E+L++ AMLSV F RP + AD
Sbjct: 554 DLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSV-PQCFVRPTEAKKAADE 612
Query: 867 ARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARDVREQLEGLLERVE 926
A++ F GDHL LLNVY + ++ S QWC +NF+ +RS+ A +VR+QL +++R
Sbjct: 613 AKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFN 672
Query: 927 VGLSS----CQGDYIRVRKAITAGYFYHTARLTRSG-YRTVKQQQTVFIHPNSSLFEQQP 981
+ S + YI +RKA+ GYF A L R+G Y TVK Q V +HP S++ + +P
Sbjct: 673 LPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHP-STVLDHKP 731
Query: 982 RWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKI 1033
W+LY+E VLTTK ++R +I+ WL+++AP YY AK+ +I
Sbjct: 732 EWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRI 783
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens]
Length = 703
Score = 593 bits (1529), Expect = e-169
Identities = 310/644 (48%), Positives = 440/644 (68%), Gaps = 20/644 (3%)
Query: 391 SIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIAC 450
SI+ R+ LPVF R +L I N+Q ++I GETG GK+TQIPQYL E G+T +G +
Sbjct: 46 SIEQQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGV 105
Query: 451 TQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSE-RTVLRYMTDGMLLREFLSEP 509
TQPRRVAA++VA RVA E G LG+EVGY IRF+DCT + T ++++TDGML+RE + +P
Sbjct: 106 TQPRRVAAVTVAGRVAEERGAVLGHEVGYCIRFDDCTDQLATRIKFLTDGMLVREMMVDP 165
Query: 510 DLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFF----- 564
L YSV+M+DEAHERTL+TDI GL+K + + R +L+++VASAT+D +F FF
Sbjct: 166 LLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDFFNQNET 225
Query: 565 -----DDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQE 619
D + + GR FPVDIFY ++P DY+++ V +V++IH T+ GD+L FLTGQE
Sbjct: 226 SDPARDTCVILTVEGRTFPVDIFYLQSPVPDYIKSTVETVVKIHQTEGDGDVLAFLTGQE 285
Query: 620 EIEAACEMLQDPCR---RLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNI 676
E+E ML + R R G K R L VLP+YA LPS Q ++F+ RKV+VATN+
Sbjct: 286 EVETVVSMLIEQARALARTGMK-RHLRVLPMYAGLPSFEQMKVFERVSRSVRKVIVATNV 344
Query: 677 AETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFR 736
AETS TI GI+YV+D GF K ++YNPRT +E L V P S+ASANQRAGR GR +GKC+R
Sbjct: 345 AETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGRGGRSRSGKCYR 404
Query: 737 LYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQL 796
LYT A+ +L ++TVPE+QR++L V+L LK+LGI +++ F F+ PPP ++++ LE L
Sbjct: 405 LYTEEAFD-KLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQSMVQALELL 463
Query: 797 YALGALNHLGELTTS-GRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFY 855
YALG L+ LT G ++AE P++PM +KM+L S + CS+EIL++AAM+ + N IF
Sbjct: 464 YALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSIAAMMQIQN-IFV 522
Query: 856 RPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARDVR 915
P ++ HA F + GDHL +LN+Y + + S+WC E+F+ ++ + RA VR
Sbjct: 523 VPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIKHNKDSKWCQEHFLNYKGLVRAATVR 582
Query: 916 EQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSG-YRTVKQQQTVFIHPNS 974
EQL+ LL + +V S +GD V + I +G+F + AR +G YRT++ + IHP S
Sbjct: 583 EQLKKLLVKFQVPRKSSEGDPDLVLRCIVSGFFANAARFHSTGAYRTIRDDHELHIHPAS 642
Query: 975 SLF-EQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYK 1017
L+ E+ PRW++Y+E++ T+K +MR V IES+WLLE+APH+Y+
Sbjct: 643 VLYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQ 686
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens]
Length = 707
Score = 547 bits (1409), Expect = e-155
Identities = 301/654 (46%), Positives = 416/654 (63%), Gaps = 19/654 (2%)
Query: 376 EPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQY 435
+PSA P E+++ RRSLP+F R +LLA + N ++ GETGSGKTTQIPQY
Sbjct: 57 QPSASP------YPEAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQY 110
Query: 436 LFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRY 495
L+E G + +G+ IA TQPRRVAA+S+A RV+ E +LG VGY++RF+D TSE T +++
Sbjct: 111 LYEGGISRQGI-IAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFDDVTSEDTRIKF 169
Query: 496 MTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPEL-----KVLV 550
+TDGMLLRE +S+ L YS V++DEAHERT+HTD+LFG++K + R EL KV+V
Sbjct: 170 LTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIV 229
Query: 551 ASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPG- 609
SATMD FS +F+ APV + GR+ P+ +FYTK P+ DYL A +VSV QIH P
Sbjct: 230 MSATMDVDLFSQYFNGAPVLYLEGRQHPIQVFYTKQPQNDYLHAALVSVFQIHQEAPSSQ 289
Query: 610 DILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARK 669
DILVFLTGQEEIEA + +D + L +LVLP+YA+LP Q R+FQ P G RK
Sbjct: 290 DILVFLTGQEEIEAMSKTCRDIAKHLPDGCPAMLVLPLYASLPYAQQLRVFQGAPKGYRK 349
Query: 670 VVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRV 729
V+++TNIAETS TI GI YV+D G K K YNP +G+E L V SK A QR GRAGR
Sbjct: 350 VIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGRE 409
Query: 730 AAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETL 789
+G C+RLYT ++ + ++ TVPEIQR +L +V+L L ++ + +++ FDF+ P + +
Sbjct: 410 DSGICYRLYTEDEFE-KFDKMTVPEIQRCNLASVMLQLLAMKVPNVLTFDFMSKPSPDHI 468
Query: 790 LLTLEQLYALGALNHLGE---LTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAM 846
+ QL LGAL H + LT GRKMA P++P +K IL S K+ C+EEILT+ ++
Sbjct: 469 QAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILMSPKFHCTEEILTIVSL 528
Query: 847 LSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFR 906
LSV +S+ + P + R F GDH+ LLN+Y + G + WC ENFV +
Sbjct: 529 LSV-DSVLHNPPSRREEVQGVRKKFISSEGDHMTLLNIYRTFKNLGGNKDWCKENFVNSK 587
Query: 907 SMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSG-YRTVKQQ 965
+M +VR QL + ++ + ++S +GD VR+ + F TA L G Y T
Sbjct: 588 NMTLVAEVRAQLRDICLKMSMPIASSRGDVESVRRCLAHSLFMSTAELQPDGTYATTDTH 647
Query: 966 QTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAK 1019
Q V IHP+S LF +P ++Y EL+ T K +MR + I++ WL E AP Y++ K
Sbjct: 648 QPVAIHPSSVLFHCKPACVVYTELLYTNKCYMRDLCVIDAQWLYEAAPEYFRRK 701
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens]
Length = 779
Score = 477 bits (1227), Expect = e-134
Identities = 276/666 (41%), Positives = 408/666 (61%), Gaps = 53/666 (7%)
Query: 400 PVFPF---REELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRV 456
P FP R++++ A+ ++ LI+ G TGSGKTTQ+P+YL+E G++ GM I TQPR+V
Sbjct: 51 PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-IGVTQPRKV 109
Query: 457 AAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSV 516
AA+SVA RVA EM LG++VGY +RF+DC+S+ T ++YMTDG LL+ L +P+L +SV
Sbjct: 110 AAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSV 169
Query: 517 VMVDEAHERTLHTDILFGLIKDVARFRP-----ELKVLVASATMDTARFSTFFDDAPVFR 571
+++DEAHERTL TDILFGL+K + + + LKV+V SATM+ A+ S FF + P+F
Sbjct: 170 IILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFD 229
Query: 572 IPGRRFPV-DIFYTKAPEAD-----YLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAAC 625
IPGR +PV + F D Y++A V + IH+ + GDILVFLTGQ EIE +C
Sbjct: 230 IPGRLYPVREKFCNLIGPRDRENTAYIQAIVEVTMDIHLNEMAGDILVFLTGQFEIEKSC 289
Query: 626 EMLQDPCRRLG-------SKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAE 678
E+L + + + LL+LP Y ++ +D Q RIF P PPG RK V++TNI+
Sbjct: 290 ELLFQMAESVDYDYDVQDTTLDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISA 349
Query: 679 TSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLY 738
TS TI+GI YV+D GF KQ ++NPR G++ L V P SK+ A QR+GRAGR ++GKCFR+Y
Sbjct: 350 TSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIY 409
Query: 739 TAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYA 798
+ + + + +PEI+RTSL +VVL LK L IHD++ F +LDPP +L L+QLY
Sbjct: 410 SKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRFPYLDPPNERLILEALKQLYQ 469
Query: 799 LGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPK 858
A++ G +T G M E P+ P L+ ++ + C + +L +AAMLSV N +F RP
Sbjct: 470 CDAIDRSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLSVEN-VFIRPV 528
Query: 859 DKVVHADNARVNFFL---PGG--DHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARD 913
D + + + L GG D L ++ Q SG + WC ++++ +R + A
Sbjct: 529 DPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSGAPASWCQKHWIHWRCLFSAFR 588
Query: 914 VREQLEGLLERVEVGLSSCQGDYIR----------VRKAITAGYFYHTARLTRSGYRTV- 962
V QL L+ +++ Q D+ + +R+ + AGYF + AR RS RT
Sbjct: 589 VEAQLRELIRKLKQ-----QSDFPKETFEGPKHEVLRRCLCAGYFKNVAR--RSVGRTFC 641
Query: 963 ---KQQQTVFIHPNSSLFEQQPR--WLLYHELVLTTKEFMRQVLEIESSWLLEVAP--HY 1015
+ V IHP+S+L EQ+ + W+++HE+++TTK + R V I W+ ++ P H
Sbjct: 642 TVDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVYARIVCPIRYEWVRDLLPKLHE 701
Query: 1016 YKAKEL 1021
+ A +L
Sbjct: 702 FNAHDL 707
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 364 bits (934), Expect = e-100
Identities = 193/400 (48%), Positives = 271/400 (67%), Gaps = 22/400 (5%)
Query: 400 PVFPF---REELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRV 456
P FP R++++ A+ ++ LI+ G TGSGKTTQ+P+YL+E G++ GM I TQPR+V
Sbjct: 51 PTFPIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGFSQHGM-IGVTQPRKV 109
Query: 457 AAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSV 516
AA+SVA RVA EM LG++VGY +RF+DC+S+ T ++YMTDG LL+ L +P+L +SV
Sbjct: 110 AAISVAQRVAEEMKCTLGSKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPNLTKFSV 169
Query: 517 VMVDEAHERTLHTDILFGLIKDV-----ARFRPELKVLVASATMDTARFSTFFDDAPVFR 571
+++DEAHERTL TDILFGL+K + + LKV+V SATM+ A+ S FF + P+F
Sbjct: 170 IILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFGNCPIFD 229
Query: 572 IPGRRFPV-DIFYTKAPEAD-----YLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAAC 625
IPGR +PV + F D Y++A V + IH+ + GDILVFLTGQ EIE +C
Sbjct: 230 IPGRLYPVREKFCNLIGPRDRENTAYIQAIVKVTMDIHLNEMAGDILVFLTGQFEIEKSC 289
Query: 626 EMLQDPCRRL-------GSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAE 678
E+L + + + LL+LP Y ++ +D Q RIF P PPG RK V++TNI+
Sbjct: 290 ELLFQMAESVDYDYDVQDTILDGLLILPCYGSMTTDQQRRIFLPPPPGIRKCVISTNISA 349
Query: 679 TSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLY 738
TS TI+GI YV+D GF KQ ++NPR G++ L V P SK+ A QR+GRAGR ++GKCFR+Y
Sbjct: 350 TSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSSGKCFRIY 409
Query: 739 TAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHF 778
+ + + + +PEI+RTSL +VVL LK L IHD++ +
Sbjct: 410 SKDFWNQCMPDHVIPEIKRTSLTSVVLTLKCLAIHDVIRY 449
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo
sapiens]
Length = 1143
Score = 355 bits (912), Expect = 9e-98
Identities = 209/549 (38%), Positives = 314/549 (57%), Gaps = 28/549 (5%)
Query: 392 IQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACT 451
+Q R +LP+ + +L + HQV+++ G+TG GK+TQ+PQYL G+++ +ACT
Sbjct: 155 LQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLAAGFSH----VACT 210
Query: 452 QPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDL 511
QPRR+A +S+A RV E + G++VGY IRFE S T + ++T G+LLR+ EP L
Sbjct: 211 QPRRIACISLAKRVGFESLSQYGSQVGYQIRFESTRSAATKIVFLTVGLLLRQIQREPSL 270
Query: 512 ASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFR 571
Y V++VDE HER LH D L G+++ + RP+LKV++ SAT++ + FS++F +APV +
Sbjct: 271 PQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVILMSATINISLFSSYFSNAPVVQ 330
Query: 572 IPGRRFPVDIFY---------TKAPEAD---YLEACVVSVLQIHVTQPPGDILVFLTGQE 619
+PGR FP+ + Y +K+ + D +L + S+ + + GD+LVFL+G
Sbjct: 331 VPGRLFPITVVYQPQEAEPTTSKSEKLDPRPFLRV-LESIDHKYPPEERGDLLVFLSGMA 389
Query: 620 EIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAET 679
EI A E Q S + +VLP+++ L Q ++F PPG RK +++TNIAET
Sbjct: 390 EISAVLEAAQ----TYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCILSTNIAET 445
Query: 680 SPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYT 739
S TI+GI +V+D G K+ SY+P+ ++ L S+ASA QR GRAGR G CFRLY
Sbjct: 446 SVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGPGVCFRLYA 505
Query: 740 AWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYAL 799
Y VPEI+R +L ++VL +KS+ + D F F++PPP +L + L
Sbjct: 506 ESDYD-AFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTFPFIEPPPPASLETAILYLRDQ 564
Query: 800 GALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKD 859
GAL+ LT G +A+LPVD ++ KM++ +S E +LT+AA LSV S F R
Sbjct: 565 GALDSSEALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSV-QSPFTRSAQ 623
Query: 860 KVVHADNARVNFFLPGGDHLVLLNVYTQWAE-----SGYSSQWCCENFVQFRSMRRARDV 914
AR GD L NV+ W + S S +WC ++ + ++
Sbjct: 624 SSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERSRNSRKWCRRRGIEEHRLYEMANL 683
Query: 915 REQLEGLLE 923
R Q + LLE
Sbjct: 684 RRQFKELLE 692
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 349 bits (895), Expect = 9e-96
Identities = 208/647 (32%), Positives = 355/647 (54%), Gaps = 34/647 (5%)
Query: 396 RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQ----YLFEEGYTNKGMKIACT 451
R LP++ + + + +Q++I+ G+ GK+ Q+PQ Y Y + G + CT
Sbjct: 59 REDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGG--VICT 116
Query: 452 QPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDL 511
Q + + +A RVA EM V +G+EVGY I FE+C + T+LRY TD ML RE +S P L
Sbjct: 117 QVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFL 176
Query: 512 ASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFR 571
SY V+++D+ HER++ TD+L GL+KDV RPELK+++ S+ ++ ++++ + PV
Sbjct: 177 GSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPVIE 236
Query: 572 IPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDP 631
+ + PV++ Y + D E+ + + +IH + GDI+VFL +++IE CE +
Sbjct: 237 VKNKH-PVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQG 295
Query: 632 CRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGA-------RKVVVATNIAETSPTIE 684
L + EL+V+P+Y P + + +F+P R+VV+ T+ E
Sbjct: 296 SN-LNPDLGELVVVPLY---PKE-KCSLFKPLDETEKRCQVYQRRVVLTTSSGEFLIWSN 350
Query: 685 GIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQ 744
+ +V+D G ++K YNPR SL + P S++ A R G ++GK F LYT
Sbjct: 351 SVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFAS 410
Query: 745 HELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGALNH 804
++ E+Q +L ++VL +K + I L H DF++ P E+L+ LE L L AL++
Sbjct: 411 KDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAALDN 470
Query: 805 LGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHA 864
G L+ G M+E P+DP LSK ILAS ++ C +E+LT+AAM++ N + P A
Sbjct: 471 DGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEAA 530
Query: 865 DNARVNFFLPGGDHLVLLNVYTQWAESGYSS-------QWCCENFVQFRSMRRARDVREQ 917
F P GDH L+++Y + ++ +S +WC + F+ ++R A +R +
Sbjct: 531 LTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAE 590
Query: 918 LEGLLERVEVGLS----SCQGDYIRVRKAITAGYFYHTAR-LTRSG-YRTVKQQQTVFIH 971
L +++R+E+ + + + + ++KA+ +GYF AR + SG Y + +Q +H
Sbjct: 591 LLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLH 650
Query: 972 PNS--SLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYY 1016
P S S+ ++ P W+L+H+ ++ ++R EI +++ P YY
Sbjct: 651 PLSGYSITKKMPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYY 697
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 291 bits (746), Expect = 2e-78
Identities = 213/643 (33%), Positives = 337/643 (52%), Gaps = 31/643 (4%)
Query: 396 RRSLPVFPFREELLAAIANHQ--VLIIEGETGSGKTTQIPQYLFEEGYTNKGMK--IACT 451
R++LP++ R L + ++ V+++ GE GSGK+TQIPQ+ E K + T
Sbjct: 42 RQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVTVT 101
Query: 452 QPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDL 511
QP +AA S+A RVA EM + LG+EVGYSI EDCT T+LR+ D +LL+E S
Sbjct: 102 QPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVASTRGT 161
Query: 512 ASYSVVMVDEAHERTLHTDILFGLIKD--VARFRPELKVLVASATMDTARFSTFFDDAPV 569
++ V+++DEA ER++ +D L GL++D + + +L+V+V + + F+ + P+
Sbjct: 162 GAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWGNPPI 221
Query: 570 FRIP---GRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACE 626
IP G R P I++ P D +EA +VL++ + PGD+LVFL +EEI CE
Sbjct: 222 VHIPREPGER-PSPIYWDTIPP-DRVEAACQAVLELCRKELPGDVLVFLPSEEEISLCCE 279
Query: 627 MLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGI 686
L L + VLP++ + +QA +++ ARKVVV +A+ S ++ I
Sbjct: 280 SLSREVESLLLQGLPPRVLPLHPDCGRAVQA-VYEDMD--ARKVVVTHWLADFSFSLPSI 336
Query: 687 IYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHE 746
+V+D G + YNPR E + P SK A R RA G C LY + E
Sbjct: 337 QHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKSFLELE 396
Query: 747 LEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGALNHLG 806
P + +L ++VLLLK I + FLD P E L+ LE L L AL+ G
Sbjct: 397 APPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQALEDLDYLAALDDDG 456
Query: 807 ELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADN 866
+L+ G ++E P+ P L+K +LAS ++ C +E+LT+AAML+ F RP + A+
Sbjct: 457 DLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPG-FTRPP---LSAEE 512
Query: 867 ARVNFFL--PGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRSMRRARDVREQLEGLLER 924
A + L GDH L+ VY + +SG WC + + ++ +A +R +L L++R
Sbjct: 513 AALRRALEHTDGDHSSLIQVYEAFIQSGADEAWCQARGLNWAALCQAHKLRGELLELMQR 572
Query: 925 VEVGLS----SCQGDYIRVRKAITAGYFYHTARLTRS-------GYRTVKQQQTVFIHPN 973
+E+ LS + + ++KA+ +GYF AR T ++ V Q + + +
Sbjct: 573 IELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSSYCCYRS 632
Query: 974 SSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYY 1016
+ P W+LYH ++ + V EI+ L+E+AP Y+
Sbjct: 633 RRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQMLVELAPPYF 675
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
sapiens]
Length = 1155
Score = 280 bits (715), Expect = 7e-75
Identities = 213/656 (32%), Positives = 322/656 (49%), Gaps = 61/656 (9%)
Query: 399 LPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIAC----TQPR 454
LPV P R+ +L AI H V++I G+TG GKTT+IPQ L E Y +G C TQPR
Sbjct: 395 LPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLER-YVTEGRGARCNVIITQPR 453
Query: 455 RVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERT-VLRYMTDGMLLREFLSEPDLAS 513
R++A+SVA RV+ E+G L VG+ +R E R L + T G+LLR+ S P L
Sbjct: 454 RISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEG 513
Query: 514 YSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIP 573
S V+VDE HER ++TD L L+K + R P L++++ SAT D RFS +F PV ++P
Sbjct: 514 VSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVP 573
Query: 574 GRRFPVDIFY-----TKAPEADYL---------EACVVS-------VLQIHVTQPPGDIL 612
G +PV Y K + YL + C + VL I PG IL
Sbjct: 574 GFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGIL 633
Query: 613 VFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVV 672
FL G +EI+ + LQ+ LG + L+LP+++N+P Q IFQ P G RK+V+
Sbjct: 634 CFLPGWQEIKGVQQRLQEA---LGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVL 690
Query: 673 ATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAG 732
ATNIAETS TI I++V+D G K++ Y+ +T + L S+A+ QR GRAGR +G
Sbjct: 691 ATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSG 750
Query: 733 KCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFL----DPPPYET 788
+ L+ + ++ VPEI RT L N+VL K + + + +FL D P +
Sbjct: 751 FAYHLFPR-SRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLSKAVDSPNIKA 808
Query: 789 LLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLS 848
+ + L +G L+ LTT G+++A + DP L+K I+ + + C +L V + L+
Sbjct: 809 VDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT 868
Query: 849 ---VNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYT------QWAESGYSSQWCC 899
++S+ R + V A + + G DHL + +W + +
Sbjct: 869 RDPFSSSLQNRAEVDKVKALLSHDS----GSDHLAFVRAVAGWEEVLRWQDRSSRENYLE 924
Query: 900 ENFVQFRSMRRARDVREQL-EGLLERVEVG------LSSCQGDYIRVRKAITAGYFYHTA 952
EN + S+R + +Q E + E VG L+S Q + + + G
Sbjct: 925 ENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGL 984
Query: 953 RLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWL 1008
R K + PNS + + +L H+ + R+ + S WL
Sbjct: 985 YPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTIN-----REATRLRSRWL 1035
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
sapiens]
Length = 1194
Score = 280 bits (715), Expect = 7e-75
Identities = 213/656 (32%), Positives = 322/656 (49%), Gaps = 61/656 (9%)
Query: 399 LPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIAC----TQPR 454
LPV P R+ +L AI H V++I G+TG GKTT+IPQ L E Y +G C TQPR
Sbjct: 434 LPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLER-YVTEGRGARCNVIITQPR 492
Query: 455 RVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERT-VLRYMTDGMLLREFLSEPDLAS 513
R++A+SVA RV+ E+G L VG+ +R E R L + T G+LLR+ S P L
Sbjct: 493 RISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSRGGALLFCTVGILLRKLQSNPSLEG 552
Query: 514 YSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIP 573
S V+VDE HER ++TD L L+K + R P L++++ SAT D RFS +F PV ++P
Sbjct: 553 VSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVP 612
Query: 574 GRRFPVDIFY-----TKAPEADYL---------EACVVS-------VLQIHVTQPPGDIL 612
G +PV Y K + YL + C + VL I PG IL
Sbjct: 613 GFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGIL 672
Query: 613 VFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVV 672
FL G +EI+ + LQ+ LG + L+LP+++N+P Q IFQ P G RK+V+
Sbjct: 673 CFLPGWQEIKGVQQRLQEA---LGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVL 729
Query: 673 ATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAG 732
ATNIAETS TI I++V+D G K++ Y+ +T + L S+A+ QR GRAGR +G
Sbjct: 730 ATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSG 789
Query: 733 KCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFL----DPPPYET 788
+ L+ + ++ VPEI RT L N+VL K + + + +FL D P +
Sbjct: 790 FAYHLFPR-SRLEKMVPFQVPEILRTPLENLVLQAK-IHMPEKTAVEFLSKAVDSPNIKA 847
Query: 789 LLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLS 848
+ + L +G L+ LTT G+++A + DP L+K I+ + + C +L V + L+
Sbjct: 848 VDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT 907
Query: 849 ---VNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYT------QWAESGYSSQWCC 899
++S+ R + V A + + G DHL + +W + +
Sbjct: 908 RDPFSSSLQNRAEVDKVKALLSHDS----GSDHLAFVRAVAGWEEVLRWQDRSSRENYLE 963
Query: 900 ENFVQFRSMRRARDVREQL-EGLLERVEVG------LSSCQGDYIRVRKAITAGYFYHTA 952
EN + S+R + +Q E + E VG L+S Q + + + G
Sbjct: 964 ENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGL 1023
Query: 953 RLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWL 1008
R K + PNS + + +L H+ + R+ + S WL
Sbjct: 1024 YPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTIN-----REATRLRSRWL 1074
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo
sapiens]
Length = 1270
Score = 258 bits (660), Expect = 2e-68
Identities = 186/608 (30%), Positives = 296/608 (48%), Gaps = 84/608 (13%)
Query: 385 QAQQKESIQAV---RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGY 441
Q +Q +QA+ R LPV F E+L AI+ + V+II G TG GKTTQ+PQ++ ++
Sbjct: 371 QLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVIIRGATGCGKTTQVPQFILDDFI 430
Query: 442 TN---KGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSE-RTVLRYMT 497
N I TQPRR++A+SVA RVA E G + G GYS+RFE + + T
Sbjct: 431 QNDRAAECNIVVTQPRRISAVSVAERVAFERGEEPGKSCGYSVRFESILPRPHASIMFCT 490
Query: 498 DGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDT 557
G+LLR+ E + S V+VDE HER ++TD L +++DV + PE+++++ SAT+DT
Sbjct: 491 VGVLLRKL--EAGIRGISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDT 548
Query: 558 ARFSTFFDDAPVFRIPGRRFPVDIFYTK-------------------------------- 585
+ F +F + P+ + GR +PV ++ +
Sbjct: 549 SMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQMTHFVPPPKDKKKKDKDDDGGEDDDANC 608
Query: 586 --------APEA--------------DYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEA 623
PE + +EA + + ++V PG +LVFL G I
Sbjct: 609 NLICGDEYGPETRLSMSQLNEKETPFELIEALLKYIETLNV---PGAVLVFLPGWNLIYT 665
Query: 624 ACEMLQ-DPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPT 682
+ L+ +P GS +LP+++ +P + Q ++F P P G KV+++TNIAETS T
Sbjct: 666 MQKHLEMNP--HFGS--HRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSIT 721
Query: 683 IEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWA 742
I ++YV+D K K + M + SK + QR GRAGRV G CF L +
Sbjct: 722 INDVVYVIDSCKQKVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRAR 781
Query: 743 YQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHF--DFLDPPPYETLLLTLEQLYALG 800
++ LE PE+ RT L + L +K L + + F ++PPP + ++ L L
Sbjct: 782 FE-RLETHMTPEMFRTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELD 840
Query: 801 ALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKD- 859
AL+ ELT GR +A+LP++P KM++ + + I T+AA K
Sbjct: 841 ALDANDELTPLGRILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINEGKRL 900
Query: 860 KVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQ-----WCCENFVQFRSMRRARDV 914
+H + A F DH+ LL+V+ W ++ + +C + ++R +
Sbjct: 901 GYIHRNFAGNRF----SDHVALLSVFQAWDDARMGGEEAEIRFCEHKRLNMATLRMTWEA 956
Query: 915 REQLEGLL 922
+ QL+ +L
Sbjct: 957 KVQLKEIL 964
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 239 bits (610), Expect = 1e-62
Identities = 182/633 (28%), Positives = 304/633 (48%), Gaps = 97/633 (15%)
Query: 399 LPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGM--KIACTQPRRV 456
LP+ ++EE+++ I ++ V+II G TGSGK+TQ+PQY+ + Y + I TQPR++
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDH-YVQRSAYCSIVVTQPRKI 190
Query: 457 AAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSV 516
A S+A +++E LG VGY + E +E T L YMT G+LL++ +S L ++
Sbjct: 191 GASSIARWISKERAWTLGGVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAKSLMEFTH 250
Query: 517 VMVDEAHERTLHTDILFGLIKDVARFRPE-LKVLVASATMDTARFSTFF--------DDA 567
+++DE HERT D L +++ + R +KV++ SAT+ F+ +F + A
Sbjct: 251 IIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPVQNKMNPA 310
Query: 568 PVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPP------------------- 608
+F + G+ V+ +Y LE S L H+ + P
Sbjct: 311 YIFEVEGKPHSVEEYYLND-----LEHIHHSKLSPHLLEEPVITKDIYEVAVSLIQMFDD 365
Query: 609 --------------------GDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIY 648
+LVFL G EI E+L + L V P++
Sbjct: 366 LDMKESGNKAWSGAQFVLERSSVLVFLPGLGEINYMHELLTSLVHK------RLQVYPLH 419
Query: 649 ANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSY--NPRTGM 706
+++ + Q +F PG RK++++TNIAE+S T+ + YV+D FC ++ + T
Sbjct: 420 SSVALEEQNNVFLSPVPGYRKIILSTNIAESSVTVPDVKYVID--FCLTRTLVCDEDTNY 477
Query: 707 ESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLL 766
+SL ++ SK S NQR GRAGRV+ G C+RL + + + + VPE+ R LG+ +L
Sbjct: 478 QSLRLSWASKTSCNQRKGRAGRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILK 537
Query: 767 LKSLGIHD--LMHFDFLDPPPYETLLLTLEQLYALGAL----------NHLGELTTSGRK 814
+K L + + + L PP + T+ L +GAL H GELT GR
Sbjct: 538 VKLLDMGEPRALLATALSPPGLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRV 597
Query: 815 MAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFF-L 873
+A+LPV+ L K+I+ + C +E L +AA LS+ N F P + + +VNF
Sbjct: 598 LAQLPVNQQLGKLIVLGHVFGCLDECLIIAAALSLKN-FFAMPFRQHLDGYRNKVNFSGS 656
Query: 874 PGGDHLVLLNVYTQWAESGYSSQ---------WCCENFVQFRSMRRARDVREQLEGLLER 924
D + L+ + W + + W N++Q + +R ++ E+L+ + +
Sbjct: 657 SKSDCIALVEAFKTWKACRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQ 716
Query: 925 VEVGLSS----CQGDYIR----VRKAITAGYFY 949
+ + S +YI + + + AG FY
Sbjct: 717 FNMHVDSRRPVMDQEYIYKQRFILQVVLAGAFY 749
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 211 bits (536), Expect = 4e-54
Identities = 152/445 (34%), Positives = 226/445 (50%), Gaps = 57/445 (12%)
Query: 642 LLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSYN 701
L VLP+Y+ L + QA++F+P P G R VVATN+AETS TI GI YV+D G K++ Y+
Sbjct: 588 LHVLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYD 647
Query: 702 PRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLG 761
TG+ S VT S+ASA+QRAGRAGR G C+RLY++ A + E+ PEI R +
Sbjct: 648 RVTGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSS-AVFGDFEQFPPPEITRRPVE 706
Query: 762 NVVLLLKSLGIHDLMHFDFLDPPPYETLLLTLEQLYALGAL--------------NHLG- 806
+++L +K+L + +++F F PP E LL E L ALGAL N L
Sbjct: 707 DLILQMKALNVEKVINFPFPTPPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSC 766
Query: 807 ELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHAD- 865
+T GR MA PV P +KM+ S ++ C +T+ A ++V + D+ +D
Sbjct: 767 PITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRE--LFEELDRPAASDE 824
Query: 866 --------NARV----------NFFLPGGDHLVLLNVYTQWAESGYSSQWCCENFVQFRS 907
ARV L GD +VLL + + Q+C N +++++
Sbjct: 825 ELTRLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQFCEANGLRYKA 884
Query: 908 MRRARDVREQLEGLLERV--EVGL-------SSCQGDYIRVRKAITAGYFYHTARLT--- 955
M R +R QL + V E L + +R+ +TAG H AR
Sbjct: 885 MMEIRRLRGQLTTAVNAVCPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARRVQSE 944
Query: 956 -------RSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWL 1008
R+ Y+T VFIHP+S LF++ P +++Y E+V TTK +M+ V +E W+
Sbjct: 945 EMLEDKWRNAYKTPLLDDPVFIHPSSVLFKELPEFVVYQEIVETTKMYMKGVSSVEVQWI 1004
Query: 1009 LEVAPHYYK-AKELEDPHAKKMPKK 1032
+ P Y + K LE+P P++
Sbjct: 1005 PALLPSYCQFDKPLEEPAPTYCPER 1029
Score = 207 bits (526), Expect = 5e-53
Identities = 155/506 (30%), Positives = 253/506 (50%), Gaps = 45/506 (8%)
Query: 143 KGKKKTGG--SKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERS 200
KG+++ G SK E P + E E +++ L+ ++ +A +++ K + + ++
Sbjct: 11 KGRQQAGPGPSKGPPEPPPVQLELE--DKDTLKGVDASNALVLPGKKKKKTKAPPLSKKE 68
Query: 201 DKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDV 260
K ++ +K L+ E ++ +K R E L +KL +++A A+ +
Sbjct: 69 KKPLTKKEKKVLQKILEQKE------KKSQRAEML-----QKLSEVQASEAEMRLFYTTS 117
Query: 261 ELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESG 320
+L R ++ A E A G QEK+ + + H K R A + EEES
Sbjct: 118 KLGTGNRMY-----HTKEKADEVVAPG-QEKISSLSGAHR-KRRRWPSAEEEEEEEEESE 170
Query: 321 APGEEQRRWEE--------ARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQ 372
+ EE+ +E A +G A S +P + T+ A
Sbjct: 171 SELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQP-----VPAGMTVPPPPAAAPP 225
Query: 373 GDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQI 432
+ P + +Q R LP+ + ++ A+A H ++I+ GETGSGKTTQ+
Sbjct: 226 LPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSGKTTQV 285
Query: 433 PQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTV 492
PQ+L+E G++++ I T+PRRVAA++++ RVA+EM + V Y IR+E +E T
Sbjct: 286 PQFLYEAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMNLS-QRVVSYQIRYEGNVTEETR 344
Query: 493 LRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPE----LKV 548
+++MTDG+LL+E + L Y VV++DEAHER+++TDIL GL+ + R + LK+
Sbjct: 345 IKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSRIVTLRAKRNLPLKL 404
Query: 549 LVASATMDTARFS----TFFDDAPVFRIPGRRFPVDIFYTK-APEADYLEACVVSVLQIH 603
L+ SAT+ F+ F PV ++ R+FPV + + K P DY C V +IH
Sbjct: 405 LIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTVHFNKRTPLEDYSGECFRKVCKIH 464
Query: 604 VTQPPGDILVFLTGQEEIEAACEMLQ 629
P G ILVFLTGQ E+ A C L+
Sbjct: 465 RMLPAGGILVFLTGQAEVHALCRRLR 490
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 196 bits (497), Expect = 1e-49
Identities = 123/346 (35%), Positives = 187/346 (54%), Gaps = 11/346 (3%)
Query: 590 DYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYA 649
+ +EA + ++ + PPG ILVFL G EI+ E LQ + ++ P+++
Sbjct: 829 ELIEALLEWIVDGKHSYPPGAILVFLPGLAEIKMLYEQLQSNSLFNNRRSNRCVIHPLHS 888
Query: 650 NLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESL 709
+L S+ Q +F P G K++++TNIAETS TI+ ++YV+D G K+K Y+ GMESL
Sbjct: 889 SLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVYVIDSGKMKEKRYDASKGMESL 948
Query: 710 TVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKS 769
T S+A+A QR GRAGRVA+G CF L+T+ Y H+L + +PEIQR L + L +K
Sbjct: 949 EDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLLKQQLPEIQRVPLEQLCLRIKI 1008
Query: 770 L---GIHDL--MHFDFLDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMAELPVDPML 824
L H+L + ++PP ++L + +L LGAL LT G +A LPVD +
Sbjct: 1009 LEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALTPDERLTPLGYHLASLPVDVRI 1068
Query: 825 SKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNV 884
K++L + C + LT+AA L+ S F P DK A+ ++ F D+L LL
Sbjct: 1069 GKLMLFGSIFRCLDPALTIAASLAF-KSPFVSPWDKKEEANQKKLEFAFANSDYLALLQA 1127
Query: 885 YTQWAES-----GYSSQWCCENFVQFRSMRRARDVREQLEGLLERV 925
Y W S S +C +NF+ R ++ ++ Q LL +
Sbjct: 1128 YKGWQLSTKEGVRASYNYCRQNFLSGRVLQEMASLKRQFTELLSDI 1173
Score = 172 bits (437), Expect = 1e-42
Identities = 91/201 (45%), Positives = 127/201 (63%), Gaps = 3/201 (1%)
Query: 386 AQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKG 445
++Q +SI R+SLP + RE +L + HQV++I G TG GKTTQIPQ++ ++
Sbjct: 531 SRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKTTQIPQFILDDSLNGPP 590
Query: 446 MKIA---CTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLL 502
K+A CTQPRR++A+SVA RVA+E ++G VGY IR E S T L Y T G+LL
Sbjct: 591 EKVANIICTQPRRISAISVAERVAKERAERVGLTVGYQIRLESVKSSATRLLYCTTGVLL 650
Query: 503 REFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFST 562
R + L S ++VDE HERT +D L ++KD+ RP L+V++ SAT++ FS
Sbjct: 651 RRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIVSQRPGLQVILMSATLNAELFSD 710
Query: 563 FFDDAPVFRIPGRRFPVDIFY 583
+F+ PV IPGR FPVD F+
Sbjct: 711 YFNSCPVITIPGRTFPVDQFF 731
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 194 bits (493), Expect = 4e-49
Identities = 146/458 (31%), Positives = 228/458 (49%), Gaps = 32/458 (6%)
Query: 579 VDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSK 638
VD+ + L V + I + + G ILVFL G + I ++L ++ K
Sbjct: 459 VDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMS---QVMFK 515
Query: 639 IRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQK 698
+ L++P+++ +P+ Q ++F+ TPPG RK+V+ATNIAETS TI+ ++YV+D G K+
Sbjct: 516 SDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKET 575
Query: 699 SYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRT 758
++ + + +++ SKA+A QR GRAGRV G C+ LY L++ +PEI RT
Sbjct: 576 HFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNG-LRASLLDDYQLPEILRT 634
Query: 759 SLGNVVLLLKSLGIHDLMHF--DFLDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMA 816
L + L +K L + + +F +DPP E +LL++ L L AL+ ELT G +A
Sbjct: 635 PLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLA 694
Query: 817 ELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFL-PG 875
LPV+P + KMIL + C + +LT+AA LS + F P K AD R
Sbjct: 695 RLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP-FVIPLGKEKIADARRKELAKDTR 753
Query: 876 GDHLVLLNVYTQWAES-----GYSSQWCCENFVQFRSMRRARDVREQL-EGLLERVEVGL 929
DHL ++N + W E+ Y +C E F+ +++ +++ Q E LL V
Sbjct: 754 SDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSS 813
Query: 930 -------SSCQGDYIRVRKA-ITAGYFYHTA--RLTRSGYRTV-----KQQQTVFIHPNS 974
S+ D ++ KA I AG + A RL R + K V +HP S
Sbjct: 814 RNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKS 873
Query: 975 SLFEQQP---RWLLYHELVLTTKEFMRQVLEIESSWLL 1009
EQ WL+YH + T+ ++ E+ LL
Sbjct: 874 VNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLL 911
Score = 154 bits (390), Expect = 3e-37
Identities = 105/335 (31%), Positives = 168/335 (50%), Gaps = 33/335 (9%)
Query: 277 RDLAREYRAAGEQEKLEATNR----YHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEA 332
R++ Y Q+ EA + HM + Q + ++ V+ ++ E Q W
Sbjct: 60 REIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAP 119
Query: 333 RLGAASLKFGARDAASQEPKY-----QLVLEEEETIEFVRATQLQGDEE---PSAPPTST 384
+ ++ E K +L+ +E++ + + D E P T
Sbjct: 120 EDHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGT 179
Query: 385 QAQ------QKES-------IQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQ 431
Q QK+ +Q R LP + ++EL+ I NHQV +I GETG GKTTQ
Sbjct: 180 LDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQ 239
Query: 432 IPQYLFEEGYTNKGM----KIACTQPRRVAAMSVAARVAREMGVKLG--NEVGYSIRFED 485
+ Q++ + Y +G +I CTQPRR++A+SVA RVA E G N GY IR +
Sbjct: 240 VTQFILDN-YIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQS 298
Query: 486 -CTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRP 544
++ + Y T G++L+ S+P L+S S +++DE HER L +D+L ++KD+ FR
Sbjct: 299 RLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRS 358
Query: 545 ELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPV 579
+LKV++ SAT++ +FS +F + P+ IPG FPV
Sbjct: 359 DLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPV 393
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 179 bits (455), Expect = 9e-45
Identities = 145/458 (31%), Positives = 219/458 (47%), Gaps = 46/458 (10%)
Query: 579 VDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDPCRRLGSK 638
VD+ + L V + I + + G ILVFL G + I S
Sbjct: 459 VDVIEMMEDDKVDLNLIVALIRYIVLEEEDGAILVFLPGWDNI---------------ST 503
Query: 639 IRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSPTIEGIIYVLDPGFCKQK 698
+ +LL+ + S Q ++F+ TPPG RK+V+ATNIAETS TI+ ++YV+D G K+
Sbjct: 504 LHDLLMSQVM--FKSVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKET 561
Query: 699 SYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRT 758
++ + + +++ SKA+A QR GRAGRV G C+ LY L++ +PEI RT
Sbjct: 562 HFDTQNNISTMSAEWVSKANAKQRKGRAGRVQPGHCYHLYNG-LRASLLDDYQLPEILRT 620
Query: 759 SLGNVVLLLKSLGIHDLMHF--DFLDPPPYETLLLTLEQLYALGALNHLGELTTSGRKMA 816
L + L +K L + + +F +DPP E +LL++ L L AL+ ELT G +A
Sbjct: 621 PLEELCLQIKILRLGGIAYFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLA 680
Query: 817 ELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFL-PG 875
LPV+P + KMIL + C + +LT+AA LS + F P K AD R
Sbjct: 681 RLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP-FVIPLGKEKIADARRKELAKDTR 739
Query: 876 GDHLVLLNVYTQWAES-----GYSSQWCCENFVQFRSMRRARDVREQL-EGLLERVEVGL 929
DHL ++N + W E+ Y +C E F+ +++ +++ Q E LL V
Sbjct: 740 SDHLTVVNAFEGWEEARRRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSS 799
Query: 930 -------SSCQGDYIRVRKA-ITAGYFYHTA--RLTRSGYRTV-----KQQQTVFIHPNS 974
S+ D ++ KA I AG + A RL R + K V +HP S
Sbjct: 800 RNPKDPESNINSDNEKIIKAVICAGLYPKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKS 859
Query: 975 SLFEQQP---RWLLYHELVLTTKEFMRQVLEIESSWLL 1009
EQ WL+YH + T+ ++ E+ LL
Sbjct: 860 VNVEQTDFHYNWLIYHLKMRTSSIYLYDCTEVSPYCLL 897
Score = 154 bits (390), Expect = 3e-37
Identities = 105/335 (31%), Positives = 168/335 (50%), Gaps = 33/335 (9%)
Query: 277 RDLAREYRAAGEQEKLEATNR----YHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEA 332
R++ Y Q+ EA + HM + Q + ++ V+ ++ E Q W
Sbjct: 60 REIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAP 119
Query: 333 RLGAASLKFGARDAASQEPKY-----QLVLEEEETIEFVRATQLQGDEE---PSAPPTST 384
+ ++ E K +L+ +E++ + + D E P T
Sbjct: 120 EDHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGT 179
Query: 385 QAQ------QKES-------IQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQ 431
Q QK+ +Q R LP + ++EL+ I NHQV +I GETG GKTTQ
Sbjct: 180 LDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQ 239
Query: 432 IPQYLFEEGYTNKGM----KIACTQPRRVAAMSVAARVAREMGVKLG--NEVGYSIRFED 485
+ Q++ + Y +G +I CTQPRR++A+SVA RVA E G N GY IR +
Sbjct: 240 VTQFILDN-YIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQS 298
Query: 486 -CTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRP 544
++ + Y T G++L+ S+P L+S S +++DE HER L +D+L ++KD+ FR
Sbjct: 299 RLPRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRS 358
Query: 545 ELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPV 579
+LKV++ SAT++ +FS +F + P+ IPG FPV
Sbjct: 359 DLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPV 393
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 167 bits (422), Expect = 6e-41
Identities = 130/424 (30%), Positives = 211/424 (49%), Gaps = 38/424 (8%)
Query: 609 GDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGAR 668
G +L+FL G I+ ++L + R + + V+ +++ L + QA F PPG R
Sbjct: 868 GAVLIFLPGLAHIQQLYDLLSNDRRFYSERYK---VIALHSILSTQDQAAAFTLPPPGVR 924
Query: 669 KVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGR 728
K+V+ATNIAET TI +++V+D G K+ Y+ + M SL T SKASA QR GRAGR
Sbjct: 925 KIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGR 984
Query: 729 VAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLK--SLGIHDLMHFDFLDPPPY 786
V G CFR+YT ++ + + +VPEI R L + L + +LG + LDPP
Sbjct: 985 VRDGFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQL 1043
Query: 787 ETLLLTLEQLYALGALN-HLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAA 845
+ + + L +GA + +LT G+ +A LPV+ + KM++ + C + + T+AA
Sbjct: 1044 QVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAA 1103
Query: 846 MLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQW----AESGYSSQ--WCC 899
+++ S F P + AD A+ + DHL + N Y W E GY S+ +C
Sbjct: 1104 VMT-EKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCR 1162
Query: 900 ENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDY-------------IRVRKAI-TA 945
NF+ S+ DV+++L L++ S+ + I + KA+ A
Sbjct: 1163 RNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVA 1222
Query: 946 GYFYHTARL--TRSGYRTVK-------QQQTVFIHPNSSLFEQQPR-WLLYHELVLTTKE 995
G + + ++ T+S T K Q +HP+S + Q WLLY E + +
Sbjct: 1223 GLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARV 1282
Query: 996 FMRQ 999
++R+
Sbjct: 1283 YLRE 1286
Score = 165 bits (418), Expect = 2e-40
Identities = 153/585 (26%), Positives = 265/585 (45%), Gaps = 96/585 (16%)
Query: 71 PRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRK-----KR 125
P+ E+ ++ ++ +E N +L +E+ +EE + SL+++ K +
Sbjct: 205 PKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERY 264
Query: 126 KHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAF--AE 183
HL K + +E+ A+ K +K G K+ EK R + ++ LE+ F A
Sbjct: 265 LHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKI-------RKFQREMETLEDHPVFNPAM 317
Query: 184 RVRQRDKDRTR-------------NVLERSDKKAYEEAQKRLK----------------- 213
++ + +R + N+ E+S EE K+ +
Sbjct: 318 KISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKEPHDVRNFDYTARSWTGK 377
Query: 214 ---------MAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSR 264
+ + K+ P K Y R R + + + L D ++
Sbjct: 378 SPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQ 437
Query: 265 HERQELKYKRRV-------------RDLAREYRAAGEQEKLEATNRYHMPKETRGQPARA 311
H L R V RD+ E+ A ++K E N+ K A+
Sbjct: 438 HLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDA--EKKREELNKMETNKPRDLFIAKL 495
Query: 312 VDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE--ETIEFVRAT 369
++ ++++ ++Q+ E R + + + S E L LE E +E VR
Sbjct: 496 LNKLKQQQQ---QQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNL 552
Query: 370 --QLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSG 427
+LQ ST QK + R+ LPVF R+ ++ + H+V+++ GETGSG
Sbjct: 553 FRKLQ----------STPKYQK--LLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSG 600
Query: 428 KTTQIPQYLFEEGYTNKG----MKIACTQPRRVAAMSVAARVAREMGVKLG-----NEVG 478
K+TQ+P +L E+ N+ I CTQPRR++A+S+A RV E+G + G + G
Sbjct: 601 KSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCG 660
Query: 479 YSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKD 538
Y IR E E T L Y T G+LLR+ + L++ S V+VDE HER++ +D L ++K+
Sbjct: 661 YQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKE 720
Query: 539 VARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFY 583
+ + R +L +++ SAT+D+ +FST+F P+ RI GR +PV++F+
Sbjct: 721 ILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFH 765
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 159 bits (403), Expect = 1e-38
Identities = 116/392 (29%), Positives = 193/392 (49%), Gaps = 21/392 (5%)
Query: 609 GDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGAR 668
G +L+FL G +EI + + +R V +++N+ + Q ++ + P G R
Sbjct: 623 GAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQVFMLHSNMQTSDQKKVLKNPPAGVR 682
Query: 669 KVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGR 728
K++++TNIAETS T+ +++V+D G K+KS++ + L + SKASA QR GRAGR
Sbjct: 683 KIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGR 742
Query: 729 VAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFL----DPP 784
G CFRL++ +Q+ LE T PE+ R L + L K L + DFL +PP
Sbjct: 743 CRPGICFRLFSRLRFQNMLEFQT-PELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPP 801
Query: 785 PYETLLLTLEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVA 844
P + ++ L + A++ +LT G +A+LPV+P L KM+L + C + ILT+A
Sbjct: 802 PALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIA 861
Query: 845 AMLSVNNSIFYRPKDKVVHADNARVNFFLPG--GDHLVLLNVYTQWAES---GYSSQWCC 899
L+ + + A F G DH+ LL + W ++ G+ +C
Sbjct: 862 CTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDGWERAFCE 921
Query: 900 ENFVQFRSMRRARDVREQLEGLLE-----RVEVG-----LSSCQGDYIRVRKAITAGYFY 949
+NF+ +M +R QL G L R G +++ ++ V+ A+ AG +
Sbjct: 922 KNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYP 981
Query: 950 HTARLTRSG-YRTVKQQQTVFIHPNSSLFEQQ 980
+ + R T +++ V HP S L + Q
Sbjct: 982 NLVHVDRENLVLTGPKEKKVRFHPASVLSQPQ 1013
Score = 152 bits (384), Expect = 2e-36
Identities = 81/193 (41%), Positives = 125/193 (64%), Gaps = 2/193 (1%)
Query: 389 KESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNK-GMK 447
+ + R+SLPVF +EE++ I ++V++I GETGSGKTTQIPQ+L ++ + N +
Sbjct: 183 ESEFDSFRQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKNGIPCR 242
Query: 448 IACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLS 507
I CTQPRR+AA++VA RVA E ++G +GY IR E S +T+L + T+G+LLR ++
Sbjct: 243 IFCTQPRRLAAIAVAERVAAERRERIGQTIGYQIRLESRVSPKTLLTFCTNGVLLRTLMA 302
Query: 508 -EPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDD 566
+ L++ + V+VDE HER +D L ++D+ + P LK++++SA +D F +F
Sbjct: 303 GDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFGS 362
Query: 567 APVFRIPGRRFPV 579
PV I GR F V
Sbjct: 363 CPVIYIQGRPFEV 375
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 84.0 bits (206), Expect = 7e-16
Identities = 83/315 (26%), Positives = 129/315 (40%), Gaps = 18/315 (5%)
Query: 81 RAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEA 140
R +RE + E+NR + R K + ++RE E E E
Sbjct: 161 RQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETET 220
Query: 141 SEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLE-ERDAFAERVRQRDKDRTRNVLER 199
+ K++T + + K E E E ++ ERER + E ERD ER R RD+DR R R
Sbjct: 221 ETERKRQTDRERDRQRKTERERE-KQAERERASERETERDKERERERDRDRDRDR----R 275
Query: 200 SDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGD 259
++ + +KR + E DR+ E +++ +RE +RER + + E E E +
Sbjct: 276 QKERERQTDRKRQRRTERDRET---ERKRERQRERERERERNRKRERERERERERERQRE 332
Query: 260 VELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEES 319
E R + +E K KR+ R G + + +A +E Q AR E E
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAR-----EREE 387
Query: 320 GAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQ-GDEEPS 378
++ R +E + G R+ Q + + E E E R + Q G E
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQRER-EKDRESERGRERGREREKQKGRERDR 446
Query: 379 APPTSTQA--QQKES 391
T QA Q+K S
Sbjct: 447 ERQTDRQAGRQRKRS 461
Score = 71.2 bits (173), Expect = 5e-12
Identities = 72/309 (23%), Positives = 123/309 (39%), Gaps = 20/309 (6%)
Query: 81 RAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEA 140
R RE +++R D E+ E R ++R+K ++ +K+RE E E E
Sbjct: 79 RERRREKDRHRKRDRHRERQRDREKERERQTDR---ERDRQREKERNRQKERERETEREG 135
Query: 141 SEKGKKKTGGSKQQTEKPESEDEWER-TERERLQDLE---------ERDAFAERVRQRDK 190
++T G +++ + ++E E ER T+RER + E E++ R R+R +
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195
Query: 191 DRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELR---KKSRREYLAKREREKLEDLE 247
++ +R ++ E ++R E +RK R +K+ RE + ERE+ + E
Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255
Query: 248 AELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQ 307
E E D + R RQ K R R R+ + E+++ R + R +
Sbjct: 256 TERDKERERERDRDRDRDRRQ----KERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 308 PARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVR 367
E E E QR E R K + +E Q E E R
Sbjct: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER 371
Query: 368 ATQLQGDEE 376
+ + D +
Sbjct: 372 ERERERDRQ 380
Score = 68.9 bits (167), Expect = 2e-11
Identities = 62/258 (24%), Positives = 106/258 (41%), Gaps = 12/258 (4%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEE- 135
E+ R +RE E S R E E ET + ++R +++ ++RE++
Sbjct: 187 ERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA 246
Query: 136 EEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLE-----ERDAFAERVRQRDK 190
E E ASE+ ++ +++ ++ D ++ ERER D + ERD ER R+R +
Sbjct: 247 ERERASERETERDKERERERDRDRDRDRRQK-ERERQTDRKRQRRTERDRETERKRERQR 305
Query: 191 DRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAEL 250
+R R ++ E ++ + E + E +K +R+ RER + E
Sbjct: 306 ERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRR 365
Query: 251 ADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPAR 310
E + E R +E + + R RD R+ + EK R ET Q R
Sbjct: 366 QAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR-----ETEKQRER 420
Query: 311 AVDLVEEESGAPGEEQRR 328
D E G E+ +
Sbjct: 421 EKDRESERGRERGREREK 438
Score = 62.0 bits (149), Expect = 3e-09
Identities = 55/223 (24%), Positives = 97/223 (43%), Gaps = 17/223 (7%)
Query: 73 KAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKR 132
+A + R ERE +++R R E ++ + R + +RK+ + ++R
Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309
Query: 133 EEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDR 192
E E + + +++ +Q+ + + E E ER + + + ER+ R +R +R
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369
Query: 193 TRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSR---REYLAKREREKLEDLEAE 249
R D+++ E ++R + + DR+ +K R RE +REREK D E+E
Sbjct: 370 ERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK--DRESE 427
Query: 250 LADEEFLFGDVELSRHERQELKYKRRVRDLAREY-RAAGEQEK 291
E R+ K K R RD R+ R AG Q K
Sbjct: 428 RGRE-----------RGREREKQKGRERDRERQTDRQAGRQRK 459
Score = 61.6 bits (148), Expect = 4e-09
Identities = 67/256 (26%), Positives = 111/256 (43%), Gaps = 26/256 (10%)
Query: 78 KPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEE 137
K A +RE E+ R + E+ + R + RK+ +H ++R+ E+E
Sbjct: 47 KDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD--RHRKRDRHRERQRDREKE 104
Query: 138 EEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVL 197
E ++ K++ + E E E ER E ER +D + D ER RQRD ++ R
Sbjct: 105 RERQTDRERDRQREKERNRQKERERETER-EGERGRD-RQTDGQRERERQRDAEKER--- 159
Query: 198 ERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLF 257
ER + + +R + E +R+ K+R+E +RERE+ + E + D
Sbjct: 160 ERQTDRERQRQTERNRQKERERE--------KNRQE---RRERERQREKENKTEDRHSER 208
Query: 258 G-DVELSRHERQELKYKRRV-RDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLV 315
G + E R E + KR+ R+ R+ + E+EK +A +ET R
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTEREREK-QAERERASERETERDKER----- 262
Query: 316 EEESGAPGEEQRRWEE 331
E E + RR +E
Sbjct: 263 ERERDRDRDRDRRQKE 278
Score = 57.8 bits (138), Expect = 5e-08
Identities = 56/238 (23%), Positives = 98/238 (41%), Gaps = 13/238 (5%)
Query: 113 RAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERL 172
R GS +R+ K + ++ E +K +++ K+QTE+ R E++R
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRR-EKRQTERETDRKRERRREKDRH 88
Query: 173 QDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRR 232
+ +RD ER R R+K+R R D++ +E ++ + E + E + R
Sbjct: 89 R---KRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER----EGERGRDR 141
Query: 233 EYLAKREREKLEDLEAELADEEFLFGDVELSRH-----ERQELKYKRRVRDLAREYRAAG 287
+ +RERE+ D E E + + R+ ER++ + +RR R+ RE
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKT 201
Query: 288 EQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARD 345
E E +ET + R E E+ R ++A AS + RD
Sbjct: 202 EDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERD 259
Score = 54.3 bits (129), Expect = 6e-07
Identities = 57/263 (21%), Positives = 114/263 (43%), Gaps = 19/263 (7%)
Query: 119 QKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLE-E 177
+ ++K+R+ R+KR+ E E + + +++ +++ E + + E+ ERER D E +
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK-ERERQTDRERD 114
Query: 178 RDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAK 237
R ER RQ++++R ER ++ + + E R A E +++ RE +
Sbjct: 115 RQREKERNRQKERERE---TEREGERGRDRQTDGQRERERQRDAE-KERERQTDRERQRQ 170
Query: 238 REREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEAT-- 295
ER + ++ E E +E + + + + E ++ R R+ RE E E+ T
Sbjct: 171 TERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDR 230
Query: 296 --NRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKY 353
+R + R + A E E+ E +R + R RD +E +
Sbjct: 231 ERDRQRKTEREREKQAERERASERETERDKERERERDRDR---------DRDRRQKERER 281
Query: 354 QLVLEEEETIEFVRATQLQGDEE 376
Q + + E R T+ + + +
Sbjct: 282 QTDRKRQRRTERDRETERKRERQ 304
Score = 42.7 bits (99), Expect = 0.002
Identities = 28/120 (23%), Positives = 52/120 (43%)
Query: 78 KPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEE 137
K R E + + R R + E E R + +++R++ + +++E E +
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
Query: 138 EEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVL 197
E G+++T +++ + ESE ER Q ERD + RQ + R R+ L
Sbjct: 404 TEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTL 463
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 80.9 bits (198), Expect = 6e-15
Identities = 61/197 (30%), Positives = 105/197 (53%), Gaps = 7/197 (3%)
Query: 78 KPARAAEREA-RALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEE 136
K R +ER+ R EK + R E E ++ +++RKKR+ ++ +E EE
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 137 EEEASEKGKKKTGGSKQQTEKPESEDEWERTER-ERLQDLEERDAFAERVRQRDKDRTRN 195
+E+ +K KK+ G + ++ ++ E ++E +R ER ER + EER+ ER R+ K R R
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE--KERERKERKKRERK 169
Query: 196 VLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAE-LADEE 254
+ +++ E+ +K K E +RK E +K RRE K+ER+K E+ + E D +
Sbjct: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRE--RKKERKKKEERKKERQKDRQ 227
Query: 255 FLFGDVELSRHERQELK 271
+ + E + ER+E K
Sbjct: 228 TNWREKERGKRERKERK 244
Score = 72.4 bits (176), Expect = 2e-12
Identities = 63/225 (28%), Positives = 111/225 (49%), Gaps = 23/225 (10%)
Query: 105 ESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEAS-EKGKKKTGGSKQQTEKPESEDE 163
E ET + +RKK + R+KR+ E E+E E+GKK+ G +++ E+
Sbjct: 42 EREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEER------ 95
Query: 164 WERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMI 223
ER +R R ++ +E + +R ++ K+R R E +++ EE +KR + E +RK
Sbjct: 96 -ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEE-RKREERKERERKK-- 151
Query: 224 PELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREY 283
E K+ R+ KRER+++ + E E ++E R ER++ + R+ R RE
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKE---------RKERKKRERNRKERKKERER 202
Query: 284 RAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRR 328
+ E++K E + KE Q R + E+E G ++R+
Sbjct: 203 KERRERKK-ERKKKEERKKER--QKDRQTNWREKERGKRERKERK 244
Score = 65.1 bits (157), Expect = 3e-10
Identities = 53/182 (29%), Positives = 86/182 (47%), Gaps = 15/182 (8%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSE------ETVSRAGSSLQKKRKKRKHLRK 130
E+ R ERE E+ + + E +E E E ++ G +K++KK K R
Sbjct: 65 EREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERG 124
Query: 131 K-----REEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERV 185
+ +E E +EE + +K+ K++ EK + ER +RER Q E+ + E+
Sbjct: 125 RTSKEGKERERKEERKREERKERERKKEEREK--ERERKERKKRERKQVGEKEEERKEKE 182
Query: 186 RQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLED 245
R+ K R RN ER KK E ++R + E +K + R+K R+ ++ER K E
Sbjct: 183 RKERKKRERNRKER--KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
Query: 246 LE 247
E
Sbjct: 241 KE 242
Score = 60.1 bits (144), Expect = 1e-08
Identities = 47/171 (27%), Positives = 88/171 (51%), Gaps = 16/171 (9%)
Query: 72 RKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKK 131
+K E+ R E+E + EK + + E+ S+ G ++K ++++ RK+
Sbjct: 91 KKEERERKKRRREKENKEGEEKEKRKK----KEKKERGRTSKEGKERERKEERKREERKE 146
Query: 132 REEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKD 191
RE ++EE E+ +K+ K++ K E E ER E+ER +ER ++R K+
Sbjct: 147 RERKKEEREKERERKER---KKRERKQVGEKEEERKEKER----KERKKRERNRKERKKE 199
Query: 192 RTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREK 242
R R R KK ++ ++R K ++DR+ E +++ +RE ++ER+K
Sbjct: 200 RERKE-RRERKKERKKKEERKKERQKDRQTNWRE-KERGKRE---RKERKK 245
Score = 53.9 bits (128), Expect = 8e-07
Identities = 51/203 (25%), Positives = 91/203 (44%), Gaps = 23/203 (11%)
Query: 132 REEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKD 191
RE E E E ++GKK+ ESE + ER ERE+ R E+ R+R++
Sbjct: 39 REREREIETRKEGKKER----------ESERKKERREREK------RKREREKERKRERG 82
Query: 192 RTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELA 251
+ ++ ++K E +K+ + +E+++ E RKK ++ +R R E E E
Sbjct: 83 KKE---KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK---ERGRTSKEGKERERK 136
Query: 252 DEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGE-QEKLEATNRYHMPKETRGQPAR 310
+E E R + + K + R RE + GE +E+ + R K R + R
Sbjct: 137 EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 311 AVDLVEEESGAPGEEQRRWEEAR 333
+ +E +E+++ EE +
Sbjct: 197 KKERERKERRERKKERKKKEERK 219
Score = 47.4 bits (111), Expect = 7e-05
Identities = 44/187 (23%), Positives = 84/187 (44%), Gaps = 13/187 (6%)
Query: 157 KPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAE 216
KP ++ W+ RER +++E R E ++R+ +R + ER +K E +++ + +
Sbjct: 27 KPCTQPGWQSEIREREREIETRK---EGKKERESERKKERREREKRKREREKERKRERGK 83
Query: 217 EDRKAMIPEL---RKKSRREYLAKR--EREKLEDLEAELADEEFLFG-----DVELSRHE 266
+++K + RKK RRE K E+EK + E + G E R E
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143
Query: 267 RQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQ 326
R+E + K+ R+ RE + ++E+ + + KE + + + +E E +
Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK 203
Query: 327 RRWEEAR 333
R E +
Sbjct: 204 ERRERKK 210
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 80.5 bits (197), Expect = 8e-15
Identities = 80/304 (26%), Positives = 138/304 (45%), Gaps = 27/304 (8%)
Query: 102 DSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESE 161
+ EE + +SR S + KK + + K+E+E +E E+ +++ +++ E+ E E
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER-ERRERE 326
Query: 162 DEWERTERERLQDLE-----ERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAE 216
E ER ERER ++ E ERD +R ++RD+DR R D++ + K +
Sbjct: 327 RERER-EREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 217 EDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRV 276
E + E ++ RE +RERE+ + E E E D + R E +E Y+RR
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Query: 277 RDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGA 336
+ + A QE+L+ K+TR E E A EE+RR E A+
Sbjct: 446 LERKLREKEAAYQERLK-NWEIRERKKTR----------EYEKEAEREEERRREMAKEAK 494
Query: 337 ASLKF-GARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV 395
+F D +PKY ++ + R +++ DE + ++KE ++ +
Sbjct: 495 RLKEFLEDYDDDRDDPKYYRGSALQKRLR-DREKEMEADER-------DRKREKEELEEI 546
Query: 396 RRSL 399
R+ L
Sbjct: 547 RQRL 550
Score = 71.2 bits (173), Expect = 5e-12
Identities = 88/334 (26%), Positives = 145/334 (43%), Gaps = 41/334 (12%)
Query: 69 KVPRKAVVEKPARAAEREA---RALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKR 125
K + +EK R ERE R E+ R + E+ E R + + K+R
Sbjct: 298 KEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKER 357
Query: 126 KHLR-KKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAER 184
R ++R+ + + E S K S++++ E E E ER ERER + ER+ ER
Sbjct: 358 DRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERER-ERERER---ERERERER 413
Query: 185 VRQRDKDRTR-------NVLERSDKKAYEEAQKRLKMAEED----RKAMIPELR-KKSRR 232
R+R+++R R E ++ AYE + K+ E++ + E+R +K R
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTR 473
Query: 233 EYLAKREREKLEDLEAELADE-----EFLFGDVELSRHERQELKYKRRVRDLAREYRAAG 287
EY ++E E+ E+ E+A E EFL E +R + KY R A + R
Sbjct: 474 EY--EKEAEREEERRREMAKEAKRLKEFL----EDYDDDRDDPKY---YRGSALQKRLRD 524
Query: 288 EQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAA 347
++++EA R ++ + R L E E QR +EA + +
Sbjct: 525 REKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEA-------ERRRQPQI 577
Query: 348 SQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPP 381
QEP+ + EE++ E R ++ +EEP P
Sbjct: 578 KQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611
Score = 45.1 bits (105), Expect = 4e-04
Identities = 47/175 (26%), Positives = 72/175 (41%), Gaps = 24/175 (13%)
Query: 64 LRLWNKVPRKAVVE---KPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQK 120
L+ W RK E + R ER E R LED ++ ++ GS+LQK
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Query: 121 KRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQD----LE 176
+ R+ E+E EA E+ +K+ EK E E+ +R E D L+
Sbjct: 521 RL---------RDREKEMEADERDRKR--------EKEELEEIRQRLLAEGHPDPDAELQ 563
Query: 177 ERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSR 231
+ AER RQ + E ++K +E ++ M EE+ P L+ R
Sbjct: 564 RMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLR 618
Score = 37.7 bits (86), Expect = 0.057
Identities = 50/227 (22%), Positives = 84/227 (37%), Gaps = 28/227 (12%)
Query: 104 EESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASE-KGKKKTGGSKQQTEKPESED 162
E E+ RA L + K L K + + + + E K KKK + E ++D
Sbjct: 133 EYKEPESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDD 192
Query: 163 EWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEED---- 218
E E + +D + A +R+ + L +++ +K+ K +ED
Sbjct: 193 EEALDEETKRRDQMIKGAIEVLIREYSSE-----LNAPSQESDSHPRKKKKEKKEDIFRR 247
Query: 219 ------------RKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHE 266
K I + + + L RE K D +L +E+ G E E
Sbjct: 248 FPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEK---GKKE---KE 301
Query: 267 RQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVD 313
RQE++ +RR R+ RE + + E KE + R D
Sbjct: 302 RQEIEKERRERERERERERERREREREREREREREKEKERERERERD 348
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 79.0 bits (193), Expect = 2e-14
Identities = 73/310 (23%), Positives = 146/310 (47%), Gaps = 25/310 (8%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEE 136
E+ + ERE R E+ R YR E ++ E+ L+++R+KR+ ++R+ +
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQL-------LREEREKRRRQERERQYRK 962
Query: 137 EEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKD----- 191
+++ +K ++ G ++ + E E ++ E E LQ EE+ ER ++R ++
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYR--EEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 192 RTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAK-REREKLEDLEAEL 250
R ++ L++ +++ E +++ ++ E +R+ E ++ + L + RE + ++LE +
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 251 ADEEFLFGDVE-LSRHERQELKYKRRVRDLAREYRAAGEQEKL---EATNRYHMPKETRG 306
EE L + E L R E ++ + + R R E E+E+L E R E +
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 307 QPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFV 366
+ V EE+ E+RR +E + + Q+ + QL+ EE+E
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELE------RQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 367 RATQLQGDEE 376
R Q + +EE
Sbjct: 1195 RERQYREEEE 1204
Score = 78.2 bits (191), Expect = 4e-14
Identities = 70/281 (24%), Positives = 133/281 (47%), Gaps = 20/281 (7%)
Query: 92 EKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGS 151
E+ R + L+ +E + + R + + ++++RK K+ +EEE E K +++
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 152 KQQTEKPESEDEWERTERERLQDLEERDAFAER------VRQRDKDRTRNVLERSDKKAY 205
+Q+ + + E E +RL+ EE + +R +R+ ++R +L+R ++K
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 206 EE--AQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELS 263
E+ ++RLK +E+R+ + + R++ RR+ KRE+E E LE L EE L
Sbjct: 559 EQERREQRLKREQEERRDQLLK-REEERRQQRLKREQE--ERLEQRLKREEV----ERLE 611
Query: 264 RHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPG 323
+ ER+E + KR + R + +E+ E + + +E + + + + EEE
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQ-EERRQQQLRREQQERREQRLKREEEEERLEQ 670
Query: 324 EEQRRWEEAR----LGAASLKFGARDAASQEPKYQLVLEEE 360
+R EE R L + S+ PK+Q LE E
Sbjct: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711
Score = 76.3 bits (186), Expect = 1e-13
Identities = 78/326 (23%), Positives = 149/326 (45%), Gaps = 17/326 (5%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEE 136
E+ A ++E + ++ E SE + +R Q++R+ R R++RE+
Sbjct: 751 EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRF 810
Query: 137 EEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNV 196
E EK +++ +++ E E+E + RER Q L+E E Q D++R R+
Sbjct: 811 LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE----EDGLQEDQERRRSQ 866
Query: 197 LERSDKK---AYEEAQKRLKMAEEDRKAMIPELRKKSR-----REYLAKREREK--LEDL 246
+R D+K EE +KR + + A+ +LRK+ + E L + EREK ++
Sbjct: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Query: 247 EAELADEEFLFGDVE-LSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETR 305
E + +EE L + E L R ER++ + + R R ++ + ++E+L ++ R
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 306 GQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEF 365
+ R + +++E E+R E+ R ++ +D QE + L E E+
Sbjct: 987 EKKYREEEELQQEEEQLLREER--EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044
Query: 366 VRATQLQGDEEPSAPPTSTQAQQKES 391
R Q + +EE +++E+
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERET 1070
Score = 75.9 bits (185), Expect = 2e-13
Identities = 85/358 (23%), Positives = 153/358 (42%), Gaps = 34/358 (9%)
Query: 72 RKAVVEKPARAAEREARALLEKN-----RSYRLLEDSEESSEETVSRAGSSLQKKRKKRK 126
RK EK + ER+ R E+ + +L EE +E + LQ++ ++ +
Sbjct: 220 RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 127 HLRK---KREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAE 183
L + +RE +EEE+ ++ +++ ++Q E+ + E R ++ER + EER +
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE--Q 337
Query: 184 RVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMI---------PELRKKS--RR 232
++R+ ++R L R ++ E Q R + EE R+ + +LR++ RR
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397
Query: 233 EYLAKRE----REKLEDLEAELADEEFLFGDVELSRHE------RQELKYKRRVRDLARE 282
E +RE RE+ E +L E+ L + E RHE R+E + KR +
Sbjct: 398 EQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 283 YRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFG 342
+ E E+ E R K + + R L EE +++RR ++ R +
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 343 ARDAASQEPKYQLVLEEEETI---EFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRR 397
+E + Q L E+ + + R QL EE + Q+ + Q RR
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Score = 75.9 bits (185), Expect = 2e-13
Identities = 85/361 (23%), Positives = 158/361 (43%), Gaps = 63/361 (17%)
Query: 84 EREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEK 143
ERE R E R YR ++ ++ E+ L+++R+KR+ ++R+ EEEE ++
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQL-------LREEREKRRLQERERQYREEEELQQE 1059
Query: 144 GKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKK 203
++ G ++ + E E ++ + E LQ EE+ E ++R ++R R E + +
Sbjct: 1060 EEQLLGEERETRRRQELERQYRK--EEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Query: 204 AYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKL----------EDLEAELADE 253
EE R EE K EL ++ R E ++E E+L ++LE + +E
Sbjct: 1118 QEEEQLLR----EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 254 EFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKET-----RGQP 308
E L + E E QE +R ++ R+YR E ++ + RY + + +P
Sbjct: 1174 EELQQEEEQLLREEQE----KRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP 1229
Query: 309 ARAVDLVEEE---SGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEE---- 361
+ + + + G E+ R+ E+++L RD SQ+ L+ E++E
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQL---------RDRQSQQDLQHLLGEQQERDRE 1280
Query: 362 ---------TIEFVRATQLQGDEEPSAPPTSTQAQQKESI------QAVRRSLPVFPFRE 406
F QL+ +E+ A ++Q+++ + + RR FRE
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Query: 407 E 407
E
Sbjct: 1341 E 1341
Score = 75.1 bits (183), Expect = 3e-13
Identities = 98/378 (25%), Positives = 160/378 (42%), Gaps = 61/378 (16%)
Query: 66 LWNKVPRKAVVEKPARAAERE--------------------ARALLEKNRSYRLLEDSEE 105
LW + R+ E+ R AE E R LLE R R E+ ++
Sbjct: 173 LWRQ--RQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR--EEKQQ 228
Query: 106 SSEETVSRAGSSLQKK--RKKRKHLRKKREEEEEEE--------ASEKGKKKTGGSKQQT 155
E R ++K RK+ LRK+ E+ +EEE E+ +K + +
Sbjct: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR 288
Query: 156 EKPESEDEWERTERE----RLQDLEERDAFAERVRQRDK----DRTRNVLERSDKKAYEE 207
E+ E E + +R RE R Q+ E R+ ER Q+++ + R R +++ E
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 208 AQKRLKMAEEDRKAMIPELRKKSRREYLAKRE----REKLEDLEAELADEEFLFGDVELS 263
Q R + EE R+ + +++ RRE +RE RE+ E +L E+ L + +L
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 264 RHERQELKYK-RRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAP 322
R ++ + + RR + L RE ++K E R K R Q R L EE
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLK--REQEERRDWLKREEETER 466
Query: 323 GEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFV--RATQLQGDEEPSAP 380
E++RR ++ + RD + + L LEEEE E R QL+ ++E
Sbjct: 467 HEQERRKQQLK----------RDQEEERRERWLKLEEEERREQQERREQQLRREQEERRE 516
Query: 381 PTSTQAQQKESIQAVRRS 398
+ +++E +Q RS
Sbjct: 517 QRLKRQEEEERLQQRLRS 534
Score = 75.1 bits (183), Expect = 3e-13
Identities = 98/409 (23%), Positives = 180/409 (44%), Gaps = 45/409 (11%)
Query: 36 RCTSAEEFVQRLRDT----DTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALL 91
RC E+ +++ RD + LS RD R + R+ E+ + E E +
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ--ERERKFLEEEQQLRQ 1457
Query: 92 EKNRSYR----LLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKK 147
E++R +R LL++ EE R L+++++ R+ R ++ E+E + E +K
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKF 1517
Query: 148 TGGSKQ------QTEKPESEDEWERTER--ERLQDLEERDAFAERVRQRDKDRTRNVLER 199
+Q Q + + E + R ER +R QD + + E++RQ +++ + ER
Sbjct: 1518 LEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 200 SDKKAYEEAQKRLKMAEEDRKAMIPEL---RKKSRREYLAKREREKLED----------- 245
K EE ++++ E++RK M E R++ +++ +R+R+ ED
Sbjct: 1578 DRKFRLEE--QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 246 LEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAA--GEQEKLEATNRYHMPKE 303
L + D +FL + +L R ER++ R R E + GE+++L R +E
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Query: 304 T----RGQPARAVDLVEEESGAPGEEQRRW-EEARLGAASLKFGARDAASQEPKYQLVLE 358
R Q L EE+ E +R++ EE +L + ++ ++ +Y+ +LE
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQET----EQEQLRRQERYRKILE 1751
Query: 359 EEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREE 407
EE+ QL+ E Q +Q+ Q +R FREE
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Score = 74.3 bits (181), Expect = 5e-13
Identities = 74/322 (22%), Positives = 143/322 (44%), Gaps = 18/322 (5%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEE 136
E+ R ++ R E+ R +L + EE E R L+++++ R+ + +RE++
Sbjct: 342 EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQL 401
Query: 137 EEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNV 196
E + +++ +Q + + E E E+ + E R E+ +R+++ R+
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR----EQRLKREQEERRDW 457
Query: 197 LERSDKKAYEEAQKRLKMA----EEDRKAMIPELRKKSRREYLAKRE----REKLEDLEA 248
L+R ++ E ++R + EE+R+ +L ++ RRE +RE RE+ E E
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 249 ELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQP 308
L +E + L + R E + +R + + E+++LE R K R Q
Sbjct: 518 RLKRQE---EEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK--REQE 572
Query: 309 ARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRA 368
R L++ E + +R +E RL LK + QE + + L+ EE E R
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERL-EQRLKREEVERLEQEERREQRLKREEPEEERRQ 631
Query: 369 TQLQGDEEPSAPPTSTQAQQKE 390
L+ +E+ + +Q+E
Sbjct: 632 QLLKSEEQEERRQQQLRREQQE 653
Score = 73.6 bits (179), Expect = 9e-13
Identities = 80/320 (25%), Positives = 140/320 (43%), Gaps = 30/320 (9%)
Query: 84 EREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEK 143
E E ++ R +L D EE E + ++++++R+ + +RE+EE E K
Sbjct: 461 EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLK 520
Query: 144 GKKKTGGSKQQTEKPESEDEWERTERERLQDL----EERDAFAERVRQRDKDRTRNVLER 199
+++ ++ ++ SE + R + ER + L EE+ ER QR K ++
Sbjct: 521 RQEE---EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Query: 200 SDKKAYEEAQKRLKMAEEDR------KAMIPELRKKSRREYLAKREREKLEDLEAELADE 253
K+ E Q+RLK +E+R + + L ++ RRE KRE + E + L E
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 254 EFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVD 313
E + R E+QE RR + L RE E+E+LE + +E R Q +
Sbjct: 638 EQEERRQQQLRREQQE----RREQRLKRE----EEEERLEQRLKREHEEERREQ-----E 684
Query: 314 LVEEESGAPGEEQR----RWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRAT 369
L EEE E + +W+ A + + ++ + Q +E+E R +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 370 QLQGDEEPSAPPTSTQAQQK 389
+LQ EE A + +Q+
Sbjct: 745 ELQWQEEERAHRQQQEEEQR 764
Score = 73.6 bits (179), Expect = 9e-13
Identities = 83/343 (24%), Positives = 153/343 (44%), Gaps = 27/343 (7%)
Query: 67 WNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRK 126
W K+ + E+ R E++ R E+ R RL EE + R+ L++++++R+
Sbjct: 488 WLKLEEEERREQQERR-EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 127 HLRKKREEE---EEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAE 183
KREEE E+E ++ K++ + Q K E E +R +RE+ + LE+R E
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREE 606
Query: 184 RVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKRER--- 240
R ++R L+R + + E Q+ LK E++ + +++ RRE +RE+
Sbjct: 607 VERLEQEERREQRLKREEPEE-ERRQQLLKSEEQEERR-----QQQLRREQQERREQRLK 660
Query: 241 --EKLEDLEAELADE-EFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNR 297
E+ E LE L E E + EL+ E+++ + + + R +++ E + + +
Sbjct: 661 REEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ-SKV 719
Query: 298 YHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVL 357
Y P++ GQ R +E+ EE+RR E+ L + R +E +
Sbjct: 720 YSRPRKQEGQRRR-----QEQ-----EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW 769
Query: 358 EEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLP 400
+ + + R Q P Q + +E Q +R LP
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812
Score = 73.2 bits (178), Expect = 1e-12
Identities = 76/337 (22%), Positives = 152/337 (45%), Gaps = 56/337 (16%)
Query: 84 EREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEK 143
E E R E R YR E+ ++ E+ L+++++KR+ R+++ EEEE +K
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQL-------LREEQEKRRQERERQYREEEELQRQK 1209
Query: 144 GKKKTGGSKQQTE-----KPESE---------------------DEWERTERERLQDLE- 176
K++ Q+++ +PE E ++ + +R+ QDL+
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Query: 177 ------ERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKS 230
ERD ER R + +DR E+ +++ +EA++R + ++E+++ + E +K
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKR 1329
Query: 231 RREYLAK--REREKL------EDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLARE 282
RR+ + RE E+L + L + D +F ++ R+ L+ ++R+R RE
Sbjct: 1330 RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389
Query: 283 YRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEE----ARLGAAS 338
+ E+++L R ++ R + R EE+ + E R++ E R
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFRE----EEQQLSRQERDRKFREEEQQVRRQERE 1445
Query: 339 LKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDE 375
KF + ++ +++ EEE+ ++ QL E
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Score = 71.6 bits (174), Expect = 4e-12
Identities = 87/352 (24%), Positives = 152/352 (43%), Gaps = 36/352 (10%)
Query: 80 ARAAEREARALLEKNRSYRLLEDSEESSE----ETVSRAGSSLQKKRKKRKHLRKKREEE 135
A + E RA + S LL+D + + E R +R+++K ++RE
Sbjct: 92 ATGLDEEKRARCDGKES--LLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
Query: 136 EEEEASEKGKKKTGGSKQQTEKP--ESEDEWE-----RTERERLQDLEERDAFAERVRQR 188
E EE SEK ++ +Q+ ++ EW+ R E E+LQ + + E
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET--EEFPDE 207
Query: 189 DKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLE- 247
++ R R +LE K E+ Q+R + +DR E ++ +RE + ++E EKL++ E
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRE--RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 248 ---AELADEEFLFGDVELS--RHERQE-------LKYKRRVRDLAREYRAAGEQEKLEAT 295
EL +EE +E R ERQE L+ ++++R E R ++E+ E
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 296 NRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQL 355
R +E R Q R E+E + +R EE R + + Q+ + +
Sbjct: 326 ERREQQEERREQQLRR----EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 356 VLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREE 407
L E+ + R QL+ +++ + QQ Q +RR + +EE
Sbjct: 382 QLRREQQLR--REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Score = 70.5 bits (171), Expect = 8e-12
Identities = 74/261 (28%), Positives = 125/261 (47%), Gaps = 37/261 (14%)
Query: 72 RKAVVEKPA-RAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRK 130
RK + E+P R ERE + +++R +R EE + + G Q +R++R RK
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFR--------EEEQLLQEGEEQQLRRQERD--RK 1692
Query: 131 KREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDK 190
REEE++ E+ +K Q E+ E ER RE Q +E E+ + R +
Sbjct: 1693 FREEEQQLRRQERERKFL-----QEEQQLRRQELERKFREEEQLRQE----TEQEQLRRQ 1743
Query: 191 DRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAEL 250
+R R +LE + E Q+ L+ E DRK R E ++ERE+ + L ++
Sbjct: 1744 ERYRKILEEEQLRPEREEQQ-LRRQERDRKF---------REEEQLRQEREE-QQLRSQE 1792
Query: 251 ADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPAR 310
+D +F + E R ER+E + + + RD +YR E+E+L+ + ++ R + R
Sbjct: 1793 SDRKFR--EEEQLRQEREEQQLRPQQRD--GKYR--WEEEQLQLEEQEQRLRQERDRQYR 1846
Query: 311 AVDLVEEESGAPGEEQRRWEE 331
A + + + EEQ W+E
Sbjct: 1847 AEEQFATQEKSRREEQELWQE 1867
Score = 70.1 bits (170), Expect = 1e-11
Identities = 86/359 (23%), Positives = 153/359 (42%), Gaps = 36/359 (10%)
Query: 77 EKPARAAEREARALLEKNRSYRL---LEDSEESSEETVSRAGSSLQKKRKKRKHLRKKRE 133
E+ ++E R E+ R + LE+ + T+ + ++ RK+++ L+++ E
Sbjct: 852 EEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEE 911
Query: 134 EEEEEEASEKGKKKTGGSKQQTEKPESEDEW---------ERTERER-------LQDLEE 177
E + EE ++ +++ ++ E+ + E+E R ERER LQ EE
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971
Query: 178 RDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKK----SRRE 233
+ E ++R ++R + E + + EE R + + R+ + RKK E
Sbjct: 972 QLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEE 1031
Query: 234 YLAKREREK--LEDLEAELADEEFLFGDVELSRHERQ---ELKYKRRVRDLAREYRAAGE 288
L + EREK L++ E + +EE EL + E Q E + RR ++L R+YR E
Sbjct: 1032 QLLREEREKRRLQERERQYREEE------ELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 289 QEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAAS 348
++ E P++ R Q EEE E+ R E + L+ R+
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 349 QEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREE 407
+ + + +L EE + + Q EE Q ++E Q RR +REE
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE--QEKRRQERERQYREE 1202
Score = 70.1 bits (170), Expect = 1e-11
Identities = 63/270 (23%), Positives = 124/270 (45%), Gaps = 13/270 (4%)
Query: 65 RLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKK 124
R + K + E+ E E R E+ + YR E+ ++ E+ + +++ +
Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Query: 125 RKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAER 184
R++ +K ++EEE+ + ++K Q+ E+ E+E + E E+L EER+ +
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKR--RLQERERQYREEEELQQEEEQLLG-EERETRRRQ 1074
Query: 185 VRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLE 244
+R + + + ++ EE +KR + E + EL+++ + +RE+ + +
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 245 DLEAELADEEFLFGDVELSRHERQELK---YKRRVRDLAREYRAAGEQEKLEATNRYHMP 301
+LE + +EE E+ + E Q L+ KRR ++L R+YR E ++ E
Sbjct: 1135 ELERQYREEE------EVQQEEEQLLREEPEKRRRQELERQYREEEELQQ-EEEQLLREE 1187
Query: 302 KETRGQPARAVDLVEEESGAPGEEQRRWEE 331
+E R Q EEE +QR +E
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Score = 65.5 bits (158), Expect = 3e-10
Identities = 74/332 (22%), Positives = 151/332 (45%), Gaps = 24/332 (7%)
Query: 77 EKPARAAEREARALLEKNRSYRLLED-SEESSEETVSRAGSS----LQKKRKKRKHLRKK 131
E+ R ER + +++R +R E +E E+ +SR L++++ +R+ +K
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 132 REEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQ-DLEERDA--FAERVRQR 188
E+E++ ++G+++ +Q+ ++ EDE ERE Q +ERD E + R
Sbjct: 1597 FMEDEQQLRRQEGQQQL---RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653
Query: 189 DKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKRERE------- 241
++R + + D+K EE Q + E+ + + + + + L ++ERE
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 242 ---KLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRY 298
+ ++LE + +EE L + E + RQE +Y++ + + +Q + + +R
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQEQLRRQE-RYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 299 HMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLE 358
+E Q L +ES E+ + + R L+ RD + + QL LE
Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQER-EEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 359 E-EETIEFVRATQLQGDEEPSAPPTSTQAQQK 389
E E+ + R Q + +E+ + S + +Q+
Sbjct: 1832 EQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Score = 65.1 bits (157), Expect = 3e-10
Identities = 82/362 (22%), Positives = 153/362 (42%), Gaps = 46/362 (12%)
Query: 67 WNKVPRKAVVEKPARAAEREA----RALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKR 122
W K R+ V+ K + E R L E+ R LE E E R Q++R
Sbjct: 246 WRK--RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE----RQEEEQQQQR 299
Query: 123 KKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESE---DEWERTERERLQDLEERD 179
+R+ ++++EEE E E+ +++ +QQ E+ E + ++ ER E++ ++ EE
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 180 AFAERVRQRDKDRTRNVLERSDKKAYEEAQKR---------LKMAEEDRKAMIPELRKKS 230
+ R+++++R L R + E+ +R L+ ++ R+ ++
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 231 RREYLAKRERE--------KLEDLEAELADE-----EFLFGDVELSRHERQELKYKRRVR 277
RRE +RE+E + E E L E ++L + E RHE++ RR +
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE-----RRKQ 474
Query: 278 DLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAA 337
L R+ E+E+ E + + Q R L E+ + +R EE
Sbjct: 475 QLKRDQ----EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 338 SLKFGARDAASQEPKYQLVL--EEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV 395
L+ + QE + + +L EEE+ +E R Q E+ + +++ Q +
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 396 RR 397
+R
Sbjct: 591 KR 592
Score = 63.5 bits (153), Expect = 1e-09
Identities = 73/315 (23%), Positives = 142/315 (45%), Gaps = 27/315 (8%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSE-ESSEETVSRAGSSLQKKRKKRKHLRKKREEE 135
E+ R E+E R +++R + E E E +E R S ++K+ R+ +KR +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 136 E------EEEASEKGKKKTGGSKQQTEKPESEDEWERTER--------ERLQDLE-ERDA 180
E EEE + +++ +Q+ ++ E+E E+ +RL+ E ER
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKF 1392
Query: 181 FAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKRER 240
E + R ++R + + + D+K + E +++L E DRK R++ ++ +RER
Sbjct: 1393 LKEEQQLRCQEREQQLRQDRDRK-FREEEQQLSRQERDRK-----FREEEQQVRRQERER 1446
Query: 241 EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM 300
+ LE+ + + F + E ER+E + R+ RD R++ +Q + + +R
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD--RKFLEEEQQLRRQERDRKFR 1504
Query: 301 PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE 360
+E R Q L EE+ + QR++ + + G + ++ K++ EEE
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR---EEE 1561
Query: 361 ETIEFVRATQLQGDE 375
+ + QL E
Sbjct: 1562 QLRQEREEQQLSRQE 1576
Score = 62.0 bits (149), Expect = 3e-09
Identities = 85/356 (23%), Positives = 143/356 (40%), Gaps = 57/356 (16%)
Query: 92 EKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKRE------------EEEEEE 139
E+ R RL + EE E+ + R ++ ++R+ K+ E EE+EE
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 140 ASEKGKKKTGGSKQQTEKPESEDE-------WERTERERLQDLEERDAFAERVRQRDKDR 192
++ +++ ++Q K E E+E E E R Q+L E + E+ R+R K R
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE--QEQARERIKSR 700
Query: 193 -------TRNVLERSDKKAY-----EEAQKRLKMAEEDRKAMIPELR-KKSRREYLAKRE 239
+ + K Y +E Q+R + EE R+ EL+ ++ R + ++E
Sbjct: 701 IPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQE 760
Query: 240 REKLEDLEAE-LADEEFLFGDVELSR----HERQELKYKRRVRDLAREYRAAGEQEKLEA 294
E+ D + A+E+ G LS E++E + + R RE R E+E+ E
Sbjct: 761 EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ-QREQRFLPEEEEKEQ 819
Query: 295 TNRYHMPKETRGQ----------PARAVDLVEEESGAP-------GEEQRRWEEARLGAA 337
R +E Q RA L EEE G +EQRR ++ R
Sbjct: 820 RRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLE 879
Query: 338 SLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQ 393
+ R +P Q L +E+ + +LQ +E + Q +E Q
Sbjct: 880 EERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ 935
Score = 60.8 bits (146), Expect = 6e-09
Identities = 80/343 (23%), Positives = 153/343 (44%), Gaps = 54/343 (15%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEE- 135
E+ R ERE + +++R +R E+ +SR + + ++++ R++RE +
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFR-------EEEQQLSRQERDRKFREEEQQVRRQERERKF 1448
Query: 136 -EEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTR 194
EEE+ + + + ++Q + E + R ER+R + LEE + R R K R +
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDR-KFLEEEQQLRRQERDR-KFREQ 1506
Query: 195 NVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEE 254
+ + ++ + E +++L + RK + E ++ RR+ +R +++ +D + + +EE
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEE--QQLRRQ---ERGQQRRQDRDRKFREEE 1561
Query: 255 FLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDL 314
L R ER+E + R+ RD R++R ++ + + R M E + L
Sbjct: 1562 QL-------RQEREEQQLSRQERD--RKFRLEEQKVRRQEQERKFMEDEQQ--------L 1604
Query: 315 VEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFV-------- 366
+E G++Q R E R KF + QE + Q + +E +F+
Sbjct: 1605 RRQE----GQQQLRQERDR------KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
Query: 367 --RATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREE 407
R QL+ D + Q+ E Q +RR FREE
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQEGEE-QQLRRQERDRKFREE 1696
Score = 55.8 bits (133), Expect = 2e-07
Identities = 77/349 (22%), Positives = 142/349 (40%), Gaps = 40/349 (11%)
Query: 72 RKAVVEKPARAAEREA-RALLEKNRSYR----LLEDSEESSEETVSRAGSSLQKKRKKRK 126
RK+ EK ERE R E +R +R LL++ EE R +++ + ++
Sbjct: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE 1371
Query: 127 HLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVR 186
RK EEE+ E+ ++K +QQ E E + + + ++ E++ + ER R
Sbjct: 1372 QGRKFLEEEQRLRRQER-ERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 187 QRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDL 246
+ ++ + + ++K EE Q+ + E +K R E +ERE+ + L
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQ-----------LRQERHRKFREEEQLLQEREE-QQL 1478
Query: 247 EAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNR--------Y 298
+ D +FL + +L R ER ++ +R E + E+++L R
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538
Query: 299 HMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLE 358
+ ++ RGQ R + + EEQ R E + + QE + LE
Sbjct: 1539 QLRRQERGQQRRQ----DRDRKFREEEQLRQEREE----------QQLSRQERDRKFRLE 1584
Query: 359 EEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREE 407
E++ + + DE+ Q ++E + R + REE
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Score = 48.1 bits (113), Expect = 4e-05
Identities = 44/169 (26%), Positives = 92/169 (54%), Gaps = 20/169 (11%)
Query: 84 EREARALLEKNRSYRLLEDSE---ESSEETVSRAGSSLQKKRKKRKHLRKKREEEE--EE 138
E E L + R ++LE+ + E E+ + R +K ++ + LR++REE++ +
Sbjct: 1734 ETEQEQLRRQERYRKILEEEQLRPEREEQQLRR--QERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 139 EASEKGKKKTGGSKQQTE---KPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRN 195
E+ K +++ +++ E +P+ D R E E+LQ LEE++ +R+RQ ++DR
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQ-LEEQE---QRLRQ-ERDRQYR 1846
Query: 196 VLER--SDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREK 242
E+ + +K+ E Q+ + E+ R+ E +K R E++ ++++E+
Sbjct: 1847 AEEQFATQEKSRREEQELWQEEEQKRR---QERERKLREEHIRRQQKEE 1892
Score = 40.4 bits (93), Expect = 0.009
Identities = 42/197 (21%), Positives = 82/197 (41%), Gaps = 31/197 (15%)
Query: 73 KAVVEKPARAAEREARALL--EKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRK 130
+ ++E+ ERE + L E++R +R E + EE R+ S +K ++ + LR+
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES-DRKFREEEQLRQ 1805
Query: 131 KREEEEEEEASEKGKKKTGGSKQQTEKPES--------------------------EDEW 164
+REE++ GK + + Q E+ E ++ W
Sbjct: 1806 EREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELW 1865
Query: 165 ERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIP 224
+ E++R Q+ ER E +R++ K+ R+ K + RL + A +P
Sbjct: 1866 QEEEQKRRQE-RERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVP 1924
Query: 225 ELRKKSRREYLAKRERE 241
+R EY+ ++ +
Sbjct: 1925 -VRSSPLYEYIQEQRSQ 1940
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 75.5 bits (184), Expect = 2e-13
Identities = 77/357 (21%), Positives = 157/357 (43%), Gaps = 37/357 (10%)
Query: 60 RDFALRLWNKVPRKAVVEKPARAAE----------REARALLEKNRSYRLLEDSEESSEE 109
RD ++W++ R +EK + E RE + E+ + R E+ EE
Sbjct: 554 RDQEQKMWDQEER---MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 110 TVSRAGSSLQKKRKKRKHLRKKREEEEEE--EASEKGKKKTGGSKQQTEKPESEDE-WER 166
+ +Q++ +K +K +E+EE+ E EK ++ +Q PE +++ WE
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 167 T---ERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMI 223
E+E++Q+ EE+ E++ ++ +++ + ++ + E ++R K E+ + M
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 224 PELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREY 283
+ K +E EK+++ E E+ ++E + E E+Q L + ++ E+
Sbjct: 731 EQEEKMQEQE-------EKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ---KEKLWEH 780
Query: 284 RAAGEQEKL--EATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRW--EEARLGAASL 339
EQEK+ + ++ RGQ + + +E G+E++ W EE G
Sbjct: 781 EKMQEQEKIWEQEEKMRDQEEKMRGQEEK---MRGQEEKMRGQEEKMWGQEEKMWGQEEK 837
Query: 340 KFGARDAA-SQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAV 395
+G + QE K + ++ +E + +++G EE Q+E I V
Sbjct: 838 MWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCV 894
Score = 68.2 bits (165), Expect = 4e-11
Identities = 73/355 (20%), Positives = 156/355 (43%), Gaps = 52/355 (14%)
Query: 60 RDFALRLWNKVPRKAVVEKPARAAEREAR-ALLEKNRSYRLLEDSEESSEETVSRAGSSL 118
RD R+W + R + EK R E+E +EK R + +++ E+ + + + +
Sbjct: 393 RDQEERMWEQDER--LREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK----M 446
Query: 119 QKKRKKRKHLRKKREEEEE-EEASEKGKKKTGGSKQQTEK-------PESEDE-WERT-- 167
Q++ + R+ +K REEEE E EK +K+ +Q EK PE +++ WE+
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 168 ---------ERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEED 218
+ E+++D EE +++ +++K R + ++ + ++++ EE
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 219 RKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRD 278
+ E KK+ + RE E++ + E ++ +EE + + E E++E ++ +
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 279 LAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAAS 338
+E + ++EK + E+E +E++ WE+ RL
Sbjct: 627 WEQEEKMQEQEEK----------------------MWEQEEKMWEQEEKMWEQQRLPEQK 664
Query: 339 LKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQ 393
K + ++ K Q E+EE I + + E+ + +++ES++
Sbjct: 665 EKLWEHEKMQEQEKMQ---EQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Score = 66.2 bits (160), Expect = 1e-10
Identities = 72/365 (19%), Positives = 149/365 (40%), Gaps = 42/365 (11%)
Query: 25 HVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLW-NKVPRKAVVEKPARAA 83
H + G QR SA + D +L+ +L L+ N + + + +K A
Sbjct: 172 HHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQ 231
Query: 84 EREARALLEKNR---------------SYRLLEDSEESSEETVSRAGSSLQKKRKKRKHL 128
E+ A EK+ + L + + +E + R L+++ KK +
Sbjct: 232 EKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ 291
Query: 129 RKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQR 188
+K +EE ++GK + + E W + +R R Q+ E R+ E Q+
Sbjct: 292 EEKMWRQEERLREQEGKM----------REQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 189 DKDRTRNVLERSDKKAYEEAQKRLKMAE----------EDRKAMIPELRKKSRREYLAKR 238
+ ++ ++K +E+ +K + E E K M + +K +E
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 401
Query: 239 EREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRY 298
+ E+L + E + ++E ++ VE R E++ + +++ RD +E + E+ E +
Sbjct: 402 QDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD--QEEKMQEEERIREREKKM 459
Query: 299 HMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLE 358
+ET + + EE +E++ W++ RL K ++ ++ + + E
Sbjct: 460 REEEETMREQEEKMQKQEENMWE--QEEKEWQQQRLPEQKEKLWEQEKMQEQE--EKIWE 515
Query: 359 EEETI 363
+EE I
Sbjct: 516 QEEKI 520
Score = 63.2 bits (152), Expect = 1e-09
Identities = 52/292 (17%), Positives = 130/292 (44%), Gaps = 16/292 (5%)
Query: 102 DSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESE 161
+ EE + + ++ KK + KK ++EE+ E+ +++ +K E
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEE------RMREREKKMREE 601
Query: 162 DEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEED-RK 220
+E R + E++Q+ EE+ E +++ ++ ++K +E+ +K + E+ +
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEK----MQEQEEKMWEQEEKMWEQEEKMWEQ 657
Query: 221 AMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLA 280
+PE +K+ E+ +E+EK+++ E ++ ++E + + + + + R +
Sbjct: 658 QRLPE-QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Query: 281 REYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLK 340
+ E+E++ M ++ + ++ E+E +E++ WE+ RL K
Sbjct: 717 EREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 341 FGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESI 392
+ ++ K + E+EE + + +++G EE Q+E +
Sbjct: 777 LWEHEKMQEQEK---IWEQEEKMR-DQEEKMRGQEEKMRGQEEKMRGQEEKM 824
Score = 59.3 bits (142), Expect = 2e-08
Identities = 63/284 (22%), Positives = 126/284 (44%), Gaps = 25/284 (8%)
Query: 85 REARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREE----EEEEEA 140
R+ L E+ + R E EE + L++K ++ + K E+ EE++
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432
Query: 141 SEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERS 200
E+ KK ++ Q EK + E+ RER + + E + ++ + + N+ E+
Sbjct: 433 QEQEKK----TRDQEEKMQEEER----IREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 201 DKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDV 260
+K E Q+RL ++K + E K +E + EK+ D E E+ ++
Sbjct: 485 EK---EWQQQRL----PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 537
Query: 261 ELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESG 320
++ E Q + + ++RD +E + ++E++E + K+T Q + + EEE
Sbjct: 538 KMREQEDQMWEQEEKMRD--QEQKMWDQEERMEKKTQ-EQEKKTWDQEEK---MREEERM 591
Query: 321 APGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIE 364
E++ R EE + K ++ QE + ++ +EE+ E
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635
Score = 35.4 bits (80), Expect = 0.28
Identities = 41/215 (19%), Positives = 92/215 (42%), Gaps = 12/215 (5%)
Query: 183 ERVRQRDK---DRTRNVLERSD-KKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKR 238
E ++RD + RN + + KK E Q++L +AE ++ + +++ R+ +R
Sbjct: 201 ELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRK---LER 257
Query: 239 EREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRY 298
+ L ++ EE + EL QE K +++ + R+ EQE
Sbjct: 258 AKFLLPQVQTNTLQEEMWRQEEEL---REQEKKIRKQEEKMWRQEERLREQEGKMREQEE 314
Query: 299 HMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLE 358
M ++ + + +L E+E +++ R +E ++ K ++ +E + ++ +
Sbjct: 315 KMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQ 374
Query: 359 EEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQ 393
EE E + Q++ E+ +Q E ++
Sbjct: 375 EERLWE--QEKQMREQEQKMRDQEERMWEQDERLR 407
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 72.0 bits (175), Expect = 3e-12
Identities = 73/367 (19%), Positives = 166/367 (45%), Gaps = 41/367 (11%)
Query: 45 QRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSE 104
+RLR+ + G R+ ++ + R EK R E+E R + L + E
Sbjct: 262 ERLREQE-----GKMREQEEKMRRQEKRLREQEKELREQEKEL-------REQKKLREQE 309
Query: 105 ESSEETVSRAGSSLQKKRKKRKHLRKKREE--EEEEEASEKGKKKTGGSKQQTEKPE--S 160
E +E + +K R++ + + ++ E E+E++ E+ +K ++ E+ E
Sbjct: 310 EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLR 369
Query: 161 EDEWERTERERLQDLEERDAFAERVRQRDK---DRTRNVLERSDKKAYEEAQKRLKMAEE 217
E E E+E++ + EE+ ER+R+R+K + + E+ +K +E + +E
Sbjct: 370 EKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE 429
Query: 218 DRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFG-------DVELSRHERQEL 270
++ +PE ++K + + + EK+ + E ++ D+E ++G ++ E Q
Sbjct: 430 WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 271 KYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAV----DLVEEESGAPGEEQ 326
+ + ++RD +E + ++E++ + KE R + + + + + EE +E+
Sbjct: 490 EQEEKMRD--QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEK 547
Query: 327 RRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQA 386
+ W++ + R+ +E + +++ E+EE ++Q EE
Sbjct: 548 KTWDQEEKMREEERMREREKKMREEE-EMMREQEE--------KMQEQEEKMREQEEKMW 598
Query: 387 QQKESIQ 393
+Q+E +Q
Sbjct: 599 EQEEKMQ 605
Score = 64.7 bits (156), Expect = 4e-10
Identities = 68/340 (20%), Positives = 153/340 (45%), Gaps = 19/340 (5%)
Query: 65 RLWNKVPRKAVVEKPARAAEREARALLEK--NRSYRLLEDSEESSE-ETVSRAGSSLQKK 121
++W + R EK R E++ R E+ + RL E E E E + +Q++
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 122 RKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAF 181
+ R+ +K REEEE E+ +K + + E+ E + + ++E+L + E+
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 182 AERV-RQRDKDRTRNVLERSDKKAYEEAQKRLK---MAEEDRKAMIPELRKKSRREYLAK 237
E++ Q +K R + + +KK + + + R + M E++ K E + + E + +
Sbjct: 452 EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWE 511
Query: 238 REREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRD----LAREYRAAGEQEKLE 293
++ E+L + E + +++ ++ E R E++ + +++ D + E R ++K+
Sbjct: 512 QD-ERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMR 570
Query: 294 ATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKY 353
+E + Q +EE EE+ + +E ++ K ++ +E K
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE---EEDK- 626
Query: 354 QLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQ 393
++E+E + + + ++Q EE +Q+E ++
Sbjct: 627 ---MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
Score = 63.9 bits (154), Expect = 7e-10
Identities = 60/287 (20%), Positives = 135/287 (47%), Gaps = 15/287 (5%)
Query: 104 EESSEETVSRAGSSLQKKRKKRKHL--RKKREEEEEEEASEKGKKKTGGSK--QQTEKPE 159
+E E + +K R + + + +++R E++E EK ++ K QQ EK
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 160 SEDEWERTERERLQDLEERDAFAERVRQRDKD-RTRNVLERSDKKAYEEAQKRLKMAEED 218
E + + E+ + D EE+ ER+R+R+K R + R ++ +E ++ KM E++
Sbjct: 538 EEKKTQEQEK-KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE--KMREQE 594
Query: 219 RKAMIPELRKKSRREYLAKREREKLE-DLEAELADEEFLFGDVELSRHERQELKYKRRVR 277
K E + + + E + ++E + E + E ++ ++E + + E E++E +++ +
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 278 DLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRW--EEARLG 335
+E + ++EK++ +E + Q + + E+E G+E++ W EE G
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEEKMQ-GQEEKMREQEEKMRGQEEKMWGQEEKMWG 713
Query: 336 AASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEPSAPPT 382
+G + +E + + +++E ++ + EP PP+
Sbjct: 714 QEEKMWGQEEMREKEER---IRDQKEKMQERLPEHEERCSEPCLPPS 757
Score = 63.5 bits (153), Expect = 1e-09
Identities = 63/287 (21%), Positives = 138/287 (48%), Gaps = 26/287 (9%)
Query: 92 EKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGS 151
EK +++ EE E + + +++K R+++ E+E++ E+ +K
Sbjct: 440 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEK----M 495
Query: 152 KQQTEKPESEDEWERTERERLQDLEERDAFAERV-RQRDKDRTRNVLERSDKKAYEEAQK 210
+ Q +K ++E + ERL++ EER +++ +Q +K R + +KK +++ +
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEE- 554
Query: 211 RLKMAEEDRKAMIPELRKKSRREYLAKRER-EKLEDLEAELADEEFLFGDVELSRHERQE 269
KM EE+R + E KK R E RE+ EK+++ E ++ ++E + E E++E
Sbjct: 555 --KMREEER---MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 270 LKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRW 329
+++ + +E E++K++ +E + Q +EE EE+ R
Sbjct: 610 KMWEQEEKMWEQE-----EEDKMQEQEEMMWEQEEKMQE-------QEEKMWEQEEKMRE 657
Query: 330 EEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEE 376
+E ++ K ++ +E + ++ +EE+ E + +++G EE
Sbjct: 658 QEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE--QEEKMRGQEE 702
Score = 61.2 bits (147), Expect = 5e-09
Identities = 47/246 (19%), Positives = 115/246 (46%), Gaps = 14/246 (5%)
Query: 60 RDFALRLWNKVPRKAVVEKPARAAE---REARALLEKNRSYRLLEDSEESSEETVSRAGS 116
RD ++W++ R ++ R E RE + + ++ R + ++E ++T +
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 117 SLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDE---------WERT 167
+++R + + + + EEE E EK +++ ++Q EK ++E WE+
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 168 ERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELR 227
E+ Q+ E++ E + +++ + E+ ++ + ++ KM E++ K E +
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Query: 228 KKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAG 287
+ + E + +E + E E EE ++G E + +++ + +R+ +E R
Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE--KEERIRD 733
Query: 288 EQEKLE 293
++EK++
Sbjct: 734 QKEKMQ 739
Score = 56.2 bits (134), Expect = 2e-07
Identities = 62/307 (20%), Positives = 136/307 (44%), Gaps = 23/307 (7%)
Query: 76 VEKPARAAEREARALLEKNRSYRLLED---SEESSEETVSRAGSSLQKKRKKRKHLR--- 129
V++ R ER A+ LL + ++ L E+ EE E + +K ++ + LR
Sbjct: 210 VKELKRKLER-AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE 268
Query: 130 -KKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQR 188
K RE+EE+ EK ++ ++ EK E + R + E++Q+ EE+ E +
Sbjct: 269 GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328
Query: 189 DKDRTRNVLER--SDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDL 246
+++ ER +K E +++++ EE LR+K R RE+EK+ +
Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER----MREQEKMWEQ 384
Query: 247 EAELADEEFLFGDVELSRHE-----RQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMP 301
E ++ +EE + + R E QE K +++ ++ + +Q++L
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 302 KETRGQPARAV----DLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVL 357
+E + + + + ++ G+E++ W + ++ + ++ ++ + ++
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504
Query: 358 EEEETIE 364
+EE E
Sbjct: 505 QEERMWE 511
Score = 41.6 bits (96), Expect = 0.004
Identities = 42/180 (23%), Positives = 80/180 (44%), Gaps = 22/180 (12%)
Query: 164 WERTERERLQDL-EERDAFA----------ERVRQRDKDRTRNV-LERSDKKAYEEAQKR 211
W + +++L +ERDA + E +++++ + + L S+K + K
Sbjct: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE 212
Query: 212 LKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELK 271
LK E K ++P+++ + +E + ++E E E + EE ++ E R QE K
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEE--RLREQEGK 270
Query: 272 YKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEE 331
+ + + R+ + EQEK KE R Q L E+E +E++ WE+
Sbjct: 271 MREQEEKMRRQEKRLREQEK----ELREQEKELREQK----KLREQEEQMQEQEEKMWEQ 322
Score = 38.9 bits (89), Expect = 0.026
Identities = 41/182 (22%), Positives = 85/182 (46%), Gaps = 11/182 (6%)
Query: 41 EEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLL 100
EE + R ++ + R+ ++W + + + E+ + E+E + + E+ ++
Sbjct: 572 EEEMMREQEEKMQEQEEKMREQEEKMWEQ--EEKMQEQEEKMWEQEEK-MWEQEEEDKMQ 628
Query: 101 EDSE---ESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTGGSKQ-QTE 156
E E E E+ + +++ K R+ K RE+EE+ + E+ ++ Q Q E
Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Query: 157 KPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLER-SDKKAYEEAQKRLKMA 215
K ++E R + E++ EE+ + + + ++ R ER D+K E+ Q+RL
Sbjct: 689 KMREQEEKMRGQEEKMWGQEEK-MWGQEEKMWGQEEMREKEERIRDQK--EKMQERLPEH 745
Query: 216 EE 217
EE
Sbjct: 746 EE 747
Score = 36.6 bits (83), Expect = 0.13
Identities = 31/172 (18%), Positives = 85/172 (49%), Gaps = 19/172 (11%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEE 136
E+ + E+E + ++ + E E E+ + +++++ ++++ +E+
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 137 EE---EASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRT 193
EE E EK +++ ++Q EK + ++E R + E++Q E E++R++++
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE------EKMREQEEK-- 696
Query: 194 RNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLED 245
+ ++K + + +K +E++ E+R+K R + ++EK+++
Sbjct: 697 ---MRGQEEKMWGQEEK--MWGQEEKMWGQEEMREKEER---IRDQKEKMQE 740
Score = 34.7 bits (78), Expect = 0.48
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 8/118 (6%)
Query: 66 LWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKR 125
+W + + E+ E + R EK R E+ + EE + +Q + +K
Sbjct: 634 MWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ---EEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 126 KHLRKKREEEEEEEASEKGK-----KKTGGSKQQTEKPESEDEWERTERERLQDLEER 178
+ +K +EE+ ++ K +K G ++ EK E + + +ERL + EER
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEER 748
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 72.0 bits (175), Expect = 3e-12
Identities = 68/308 (22%), Positives = 144/308 (46%), Gaps = 40/308 (12%)
Query: 85 REARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKG 144
R+ + EK R LE+ E+ ++++ +KR+ K RE+E+ +E K
Sbjct: 428 RQEEMMWEKEEKIRELEEKMHEQEK--------IREQEEKRQEEEKIREQEKRQEQEAKM 479
Query: 145 KKKTGGSKQQTEKPESEDE--WERTER----ERLQDLEERDAFAERVRQRDKDRTRNVLE 198
++ ++Q EK ++E W + E+ E++++ E+R E RQ +K R + +
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539
Query: 199 RSDKKAYEEAQKRLKMAEE---------DRKAMIPELRKKS-RREYLAKREREKLEDLEA 248
R +K +E+ +K K E+ D++ I E +K R+E + + EK+ + E
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 249 ELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQP 308
++ ++E + + E E++E ++ + +E + ++EK+ K+ R Q
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR-----EQEKKIREQE 654
Query: 309 ARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRA 368
+ + E+E +E++ WE+ K ++ QE + ++ +EE+ E +
Sbjct: 655 EK---IREQEEMMQEQEEKMWEQEE------KMCEQEEKMQEQEEKMRRQEEKMWE--QE 703
Query: 369 TQLQGDEE 376
+L+ EE
Sbjct: 704 VRLRQQEE 711
Score = 68.2 bits (165), Expect = 4e-11
Identities = 59/294 (20%), Positives = 132/294 (44%), Gaps = 5/294 (1%)
Query: 85 REARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEE-EEASEK 143
R+ + EK R E+ EE + R + +K +K + L +K E+E+ E EK
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
Query: 144 GKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKK 203
+++ +Q+ + + W + E+ R Q+ + R+ + RQ +K + + +K+
Sbjct: 460 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR 519
Query: 204 AYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELS 263
+E R + +++ + + K +E +++ EK+ E ++ D+E + E
Sbjct: 520 QEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE-E 578
Query: 264 RHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPG 323
+ RQE K + + + + EQE++ M ++ + + E+E
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR 638
Query: 324 EEQR-RWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEE 376
+E++ R +E ++ K ++ QE + ++ +EE+ E + ++Q EE
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE--QEEKMQEQEE 690
Score = 67.8 bits (164), Expect = 5e-11
Identities = 68/343 (19%), Positives = 150/343 (43%), Gaps = 32/343 (9%)
Query: 78 KPARAAEREARALLEKNRSYRLLEDSEESS----EETVSRAGSSLQKKRKKRKHLRKKRE 133
K ++ + +A +E+N + L +E EE + +Q++ +K + +K
Sbjct: 333 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 392
Query: 134 EEEEE---------EASEKGKKKTGGSKQQTEKPESEDE--WERTERERLQDLEERDAFA 182
E+EE+ E EK +++ ++ EK ++E WE+ E++++LEE+
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKIRELEEKMHEQ 450
Query: 183 ERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEE--DRKAMIPELRKKSRREYLAKRER 240
E++R++++ R R +K E+ K + E+ +++ I E +K R+ E+
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQ 510
Query: 241 EKLEDLEAELADEEFLFGDVELSR-----------HERQELKYKRRVRDLAREYRAAGEQ 289
EK+ + E EE + ++ HE++E K+ + +E + ++
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 290 EKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQ 349
EK+ +E + + +EE EE + +E ++G K ++ Q
Sbjct: 571 EKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 630
Query: 350 EPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESI 392
E + ++ +EE+ E + +++ EE +Q+E +
Sbjct: 631 EQEEKMRRQEEKIRE--QEKKIREQEEKIREQEEMMQEQEEKM 671
Score = 60.1 bits (144), Expect = 1e-08
Identities = 58/285 (20%), Positives = 132/285 (46%), Gaps = 20/285 (7%)
Query: 66 LWNKVPRKAVVEKPARAAEREARALLEK-NRSYRLLEDSEESSEETVSRAGSSLQKKRKK 124
+W K + E+ E + R L EK + ++ E E+ EE R Q++ K
Sbjct: 419 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478
Query: 125 ----RKHLRKKREE-EEEEEASEKGKKKTGGS---KQQTEKPESEDEWERTERERLQD-- 174
+ +R++ E+ E+EE + ++K +++ ++ E E+ W + E+ R Q+
Sbjct: 479 MWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538
Query: 175 ---LEERDAFAERVRQRDKD--RTRNVLERSDKKAYEEAQKRLKMAEE--DRKAMIPELR 227
E+ E++R++++ R + ++K E+ +K + E+ +++ I E
Sbjct: 539 WRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Query: 228 KKSR-REYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAA 286
+K R +E + + + EK+ + E ++ ++E + E + RQE K + + + + +
Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE-EKMRRQEEKIREQEKKIREQEEKI 657
Query: 287 GEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEE 331
EQE++ M ++ + + E+E +E++ WE+
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Score = 58.5 bits (140), Expect = 3e-08
Identities = 61/324 (18%), Positives = 146/324 (45%), Gaps = 19/324 (5%)
Query: 75 VVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREE 134
+ E+ + E+E + + E+ R E+ EE + R + +K +K + + E
Sbjct: 377 IQEQEEKIREQEEK-IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435
Query: 135 EEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTR 194
+EE+ + K ++ E+ E+E R + +R +E++A R ++ +++
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR----QEQEAKMWRQEEKIREQEE 491
Query: 195 NVLERSDK--KAYEEAQKRLKMAEEDRKAMIPEL---RKKSRREYLAKREREKLEDLEAE 249
+ E+ +K + E+ ++ K+ EE+++ E+ +K R + R++EK+ + E +
Sbjct: 492 KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEK 551
Query: 250 LADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPA 309
+ +E E H+++E ++R+ +E + ++EK+ +E + +
Sbjct: 552 IRKQEEKMWRQEEKMHDQEE-----KIRE--QEEKVWRQEEKIREQEEKIREQEEKIREQ 604
Query: 310 RAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRAT 369
+ +EE EE+ +E ++ K ++ +E + ++ +EE+ E +
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE--QEE 662
Query: 370 QLQGDEEPSAPPTSTQAQQKESIQ 393
+Q EE +Q+E +Q
Sbjct: 663 MMQEQEEKMWEQEEKMCEQEEKMQ 686
Score = 57.4 bits (137), Expect = 7e-08
Identities = 48/247 (19%), Positives = 112/247 (45%), Gaps = 19/247 (7%)
Query: 65 RLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKK 124
++W + + + E+ + E+E + ++ + + + EE + +K R++
Sbjct: 478 KMWRQ--EEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 535
Query: 125 RKHLRKKREEEEEEEASEKGKKKTGGS-----------KQQTEKPESEDEWERTERERLQ 173
+ R+K + E+EE K ++K ++Q EK ++E R + E+++
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIR 595
Query: 174 DLEERDAFAERVRQRDKDRTRNVLER---SDKKAYEEAQKRLKMAE---EDRKAMIPELR 227
+ EE+ E + Q +++ E+ ++K E+ +K + E E K + +
Sbjct: 596 EQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 228 KKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAG 287
K +E + + + EK+ + E ++ ++E + E ++E +++ VR +E +
Sbjct: 656 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Query: 288 EQEKLEA 294
QE LEA
Sbjct: 716 HQEHLEA 722
Score = 49.7 bits (117), Expect = 1e-05
Identities = 54/254 (21%), Positives = 115/254 (45%), Gaps = 22/254 (8%)
Query: 90 LLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTG 149
L EKN + ES + + L++K ++ K L +++ + EA GK+
Sbjct: 280 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP--QQQLQAEADHLGKELQS 337
Query: 150 GSKQQTEKPESEDEWER----------TERERLQDLEER-DAFAERVR-QRDKDRTRNVL 197
S + + E + W R + E++Q+ EE+ E++R Q +K R +
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 198 ERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLF 257
R ++ E +++++ EE M + K R+E + + EK+ +LE ++ ++E +
Sbjct: 398 MRRQEEMMWEKEEKMRRQEE---MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 258 GDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEE 317
E + E + + ++R A+ +R ++EK+ + +E + R + + E
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWR---QEEKIR--EQEEKIREQEEKMWRQEEKIHE 509
Query: 318 ESGAPGEEQRRWEE 331
+ EE+R+ +E
Sbjct: 510 QEKIREEEKRQEQE 523
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/140 (20%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Query: 77 EKPARAAEREARALLEKNRSYR-LLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEE 135
E+ R E + R EK R + ++ EE E + +K +++ + +R++ E+
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 136 EEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRN 195
E+E + +++ +++ + + E WE+ E+ Q+ + ++ + RQ +K +
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Query: 196 VLERSDKKAYEEAQKRLKMA 215
V R ++ +E Q+ L+ A
Sbjct: 704 VRLRQQEEKMQEHQEHLEAA 723
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 71.6 bits (174), Expect = 4e-12
Identities = 71/316 (22%), Positives = 139/316 (43%), Gaps = 11/316 (3%)
Query: 85 REARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEE-EEASEK 143
R+ + EK R E+ EE + R + +K +K + L +K E+E+ E EK
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 412
Query: 144 GKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKK 203
+++ +Q+ + + W + E+ R Q+ + R+ + RQ +K + + +K+
Sbjct: 413 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR 472
Query: 204 AYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELS 263
+E R + +++ + + K +E +++ EK+ E ++ ++E + E
Sbjct: 473 QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE-E 531
Query: 264 RHERQELKYKRRVRDLAREYRAAGEQEKL-EATNRYHMPKETRGQPARAVDLVE-----E 317
+ RQE K R ++ RE EQEK+ E R + Q + + E E
Sbjct: 532 KMWRQEEKI-REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQE 590
Query: 318 ESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEEP 377
E EE+R+ +E ++ K ++ QE + ++ +EE+ E TQ Q EE
Sbjct: 591 EKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ--EEK 648
Query: 378 SAPPTSTQAQQKESIQ 393
+Q+E +Q
Sbjct: 649 MGEQEEKMCEQEEKMQ 664
Score = 67.4 bits (163), Expect = 7e-11
Identities = 76/344 (22%), Positives = 152/344 (44%), Gaps = 27/344 (7%)
Query: 66 LWNKVPRKAVVEKPARAAEREAR---ALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKR 122
LWN++ ++ EK R E+ + E+ R E+ EE + R + +K
Sbjct: 290 LWNRLNQQQE-EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKE 348
Query: 123 KKRKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFA 182
+K +R++ E E+E + +++ K++ + + E WE+ E++++LEE+
Sbjct: 349 EK---MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKIRELEEKMHEQ 403
Query: 183 ERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEE--DRKAMIPELRKKSRR------EY 234
E++R++++ R R +K E+ K + E+ +++ I E KK R E
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 463
Query: 235 LAKREREKLEDLEAELADEEFLFGDVELSR-----HERQELKYKRRVRDLAREYRAAGEQ 289
RE EK ++ E EE + E+ R HE++E K+ + +E + ++
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQE 523
Query: 290 EKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQ 349
EK+ +E + R + + E E+++ WEE + K ++ +
Sbjct: 524 EKIREQEEKMWRQE---EKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIR 580
Query: 350 EPKYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQ 393
E + ++ +EE+ E + + Q EE +Q+E IQ
Sbjct: 581 EQEEKVWRQEEKIRE--QEEKRQEQEEKMWKQEEKIREQEEKIQ 622
Score = 58.9 bits (141), Expect = 2e-08
Identities = 53/263 (20%), Positives = 113/263 (42%), Gaps = 22/263 (8%)
Query: 85 REARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEE-EASEK 143
R+ + E+ +R E E E+ + +++ K R+ K RE+EE+ EK
Sbjct: 480 RQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEK 539
Query: 144 GKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKD--RTRNVLERSD 201
+++ +++ + E E WE +R+ +D R E++R++++ R + +
Sbjct: 540 IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE--EKIREQEEKVWRQEEKIREQE 597
Query: 202 KKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVE 261
+K E+ +K K E+ R+ + K +E + + EK+ + E ++E G+ E
Sbjct: 598 EKRQEQEEKMWKQEEKIRE----QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQE 653
Query: 262 LSRHE-------------RQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQP 308
E RQE K + + + + + EQE++ M ++
Sbjct: 654 EKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 713
Query: 309 ARAVDLVEEESGAPGEEQRRWEE 331
+ + E+E +E++ WE+
Sbjct: 714 EQEEKMQEQEEKMRRQEEKMWEQ 736
Score = 55.8 bits (133), Expect = 2e-07
Identities = 50/236 (21%), Positives = 114/236 (48%), Gaps = 19/236 (8%)
Query: 77 EKPARAAEREARALLEKN-RSYRLLEDSEES--SEETVSRAGSSLQKKRKKRKHLRKKRE 133
E+ R E + R EK R + + EE EE + ++++++ + + R+
Sbjct: 516 EEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ 575
Query: 134 EEEEEEASEKGKKKTGGSKQQTEKPESEDE--WERTE--RERLQDLEERDAFAERVRQRD 189
EE+ E EK ++ ++Q EK + ++E W++ E RE+ + ++E++ E++R+++
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE---EKIREQE 632
Query: 190 KDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAE 249
+ + E+ + +E KM E++ K M + K +E R+ EK+ + E +
Sbjct: 633 E----KIREQEEMTQEQEE----KMGEQEEK-MCEQEEKMQEQEETMWRQEEKIREQEKK 683
Query: 250 LADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETR 305
+ ++E + E E++E +++ + +E + ++EK+ +E R
Sbjct: 684 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Score = 53.1 bits (126), Expect = 1e-06
Identities = 41/193 (21%), Positives = 95/193 (49%), Gaps = 9/193 (4%)
Query: 65 RLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKK 124
++W + R+ +K R E+ + R + + EE +E + +K R++
Sbjct: 558 KIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ 617
Query: 125 RKHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAER 184
+ ++++ E+ E+E EK +++ +++Q EK ++E + E++Q+ EE R
Sbjct: 618 EEKIQEQEEKIREQE--EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET---MWR 672
Query: 185 VRQRDKDRTRNVLERSDKKAYEEA---QKRLKMAEEDRKAMIPELRKKSRREYLAKRERE 241
++ +++ + + E+ +K +E ++ KM E++ K M + K +E +R+ E
Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK-MCEQEEKMQEQEEKMRRQEE 731
Query: 242 KLEDLEAELADEE 254
K+ + E L +E
Sbjct: 732 KMWEQEVRLRQQE 744
Score = 51.2 bits (121), Expect = 5e-06
Identities = 37/174 (21%), Positives = 82/174 (47%), Gaps = 9/174 (5%)
Query: 101 EDSEESSEETVSRAGSSLQKKRKKRKHLRKK--REEEEEEEASEKGKKKTGGSKQQTEKP 158
E+ EE V R ++++ +KR+ +K ++EE+ E EK +++ ++Q EK
Sbjct: 576 EEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 159 ESEDEWERTERERLQDLEERDAFAERVRQRDKD---RTRNVLERSDKKAYEEAQKRLKMA 215
++E + + E++ + EE+ E Q ++ R + +KK E+ +K
Sbjct: 636 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEK----I 691
Query: 216 EEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQE 269
E + M + K +E + EK+++ E ++ +E + E+ +++E
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEE 745
Score = 48.1 bits (113), Expect = 4e-05
Identities = 69/316 (21%), Positives = 141/316 (44%), Gaps = 30/316 (9%)
Query: 28 QFLIGTAQRCTSAEEFVQRL---RDTDTLDL-SGPARDFALRLWN-KVPRKA-VVEKPAR 81
Q L A + A+ +++ L RD +L+L D L+ N K+ K +VE
Sbjct: 179 QALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS 238
Query: 82 AAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEE----- 136
+ + L K +LL ++ E G LQ K L+ + EE E
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEA-DHLGKELQSVSAK---LQAQVEENELWNRL 294
Query: 137 EEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNV 196
++ EK ++ ++ EK + ++E R + E++++ EE+ E + +++ R
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR-- 352
Query: 197 LERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRR-EYLAKREREKLEDLEAELADEEF 255
R ++ +E+ +K + E M+ E +K RR E + + EK+ +LE ++ ++E
Sbjct: 353 --RQEEMMWEKEEKMRRQEE-----MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 405
Query: 256 LFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLV 315
+ E + E + + ++R A+ +R ++EK+ + +E + R + +
Sbjct: 406 IREQEEKRQEEEKIREQEKRQEQEAKMWR---QEEKIR--EQEEKIREQEKKMWRQEEKI 460
Query: 316 EEESGAPGEEQRRWEE 331
E+ EE+R+ +E
Sbjct: 461 HEQEKIREEEKRQEQE 476
Score = 37.0 bits (84), Expect = 0.097
Identities = 30/150 (20%), Positives = 72/150 (48%), Gaps = 13/150 (8%)
Query: 65 RLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKK 124
++W + + E+ + E + R EK R + EE ++E + G +K ++
Sbjct: 606 KMWKQEEKIREQEEKIQEQEEKIREQEEKIR------EQEEMTQEQEEKMGEQEEKMCEQ 659
Query: 125 RKHLRKK-----REEEEEEEASEKGKKKTGGSKQQTEKPESEDE--WERTERERLQDLEE 177
+ ++++ R+EE+ E +K +++ ++Q E + ++E WE+ E+ Q+ +
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Query: 178 RDAFAERVRQRDKDRTRNVLERSDKKAYEE 207
++ + RQ +K + V R ++ +E
Sbjct: 720 QEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 71.6 bits (174), Expect = 4e-12
Identities = 63/295 (21%), Positives = 138/295 (46%), Gaps = 16/295 (5%)
Query: 85 REARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKG 144
R+ + EK R LE+ EE + + ++ K R+ K++EEE+ E EK
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE-QEKR 411
Query: 145 KKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKA 204
+++ +Q EK ++E R + +++ EE+ E++R+ +K + + + R ++K
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
Query: 205 YEEAQ---KRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVE 261
E+ + ++ KM E+++ +RK+ + + R+ EK+ D E ++ ++E E
Sbjct: 472 REQEEIWRQKEKMHEQEK------IRKQEEKVW---RQEEKMHDQEEKIREQEEKMWRQE 522
Query: 262 LSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGA 321
E++E K + + + + EQE+ M ++ + + +EE
Sbjct: 523 EKIREQEE-KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Query: 322 PGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGDEE 376
+E+ R +E ++ K ++ QE + ++ +EE+ E + ++Q EE
Sbjct: 582 EQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE--QEEKMQEQEE 634
Score = 70.5 bits (171), Expect = 8e-12
Identities = 61/317 (19%), Positives = 148/317 (46%), Gaps = 25/317 (7%)
Query: 66 LWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKR 125
+W K + +E+ E + R L EK + + EE +E +++++ +
Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 126 KHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERV 185
++++ E+EE+ E+ KK ++ E+ + +E +R E+E + EE+ E +
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Query: 186 -RQRDKDRTRNVLERSDKKAYEEAQK----RLKMAEEDRKAMIPELRKKSRREYLAKRER 240
RQ++K + + + ++K + + +K K+ E++ K E + + + E + ++E
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE- 536
Query: 241 EKLEDLEAELADEEFLFGDVELSRHERQEL-KYKRRVRDLAREYRAAGEQEKLEATNRYH 299
EK+ + E + ++E G+ E E++++ + + ++R+ + R E+ + + +
Sbjct: 537 EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596
Query: 300 MPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEE 359
++ R E+E +E++ WE+ K ++ QE + ++ +E
Sbjct: 597 QEEKIR----------EQEEMMQEQEEKMWEQEE------KMCEQEEKMQEQEEKMRRQE 640
Query: 360 EETIEFVRATQLQGDEE 376
E+ E + +L+ EE
Sbjct: 641 EKMWE--QEVRLRQQEE 655
Score = 68.6 bits (166), Expect = 3e-11
Identities = 79/333 (23%), Positives = 142/333 (42%), Gaps = 33/333 (9%)
Query: 78 KPARAAEREARALLEKNRSYRLLEDSEESS----EETVSRAGSSLQKKRKK-RKHLRKKR 132
K ++ + +A +E+N + L +E EE + +Q++ +K R+ K R
Sbjct: 272 KELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIR 331
Query: 133 EEEE-----EEEASEKGKKKTGGSKQQTEKPES-----EDEWERTERERLQDLEERDAFA 182
E+EE EE EK +K + EK E E WE+ E++++LEE+
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK--EEKIRELEEKMHEQ 389
Query: 183 ERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEE--DRKAMIPELRKKSRREYLAKRER 240
E++R++++ R R +K E+ K + E+ +++ I E KK R+ E+
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ 449
Query: 241 EKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHM 300
EK+ + E EE RQE K R ++ R+ EQEK+
Sbjct: 450 EKIREEEKRQEQEEMW----------RQEEKI-REQEEIWRQKEKMHEQEKIRKQEEKVW 498
Query: 301 PKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE 360
+E + +EE EE+ R +E ++ K ++ QE + ++ +EE
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558
Query: 361 ETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQ 393
+ E +++ EE +QKE I+
Sbjct: 559 KMQE---QEKMRRQEEKIREQEEKIREQKEKIR 588
Score = 58.5 bits (140), Expect = 3e-08
Identities = 63/324 (19%), Positives = 144/324 (44%), Gaps = 14/324 (4%)
Query: 75 VVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREE 134
+ E+ + E+E + + E+ R E+ EE + R + +K +K + L + E
Sbjct: 316 IQEQEEKIREQEEK-IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 135 EEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTR 194
+EE+ + K ++ E+ E+E R + +R +E++A R ++ +++
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR----QEQEAKMWRQEEKIREQEE 430
Query: 195 NVLERSDK--KAYEEAQKRLKMAEEDRKAMIPEL---RKKSRREYLAKREREKLEDLEAE 249
+ E+ K + E+ ++ K+ EE+++ E+ +K R + R++EK+ + E
Sbjct: 431 KIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490
Query: 250 LADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPA 309
EE ++ E H+++E K + + + R+ EQE+ + ++
Sbjct: 491 RKQEEKVWRQEE-KMHDQEE-KIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548
Query: 310 RAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRAT 369
+ + E+E +E+ R +E ++ K + +E + ++ +EE+ E +
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE--QEE 606
Query: 370 QLQGDEEPSAPPTSTQAQQKESIQ 393
+Q EE +Q+E +Q
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKMQ 630
Score = 52.0 bits (123), Expect = 3e-06
Identities = 54/272 (19%), Positives = 120/272 (44%), Gaps = 27/272 (9%)
Query: 90 LLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEASEKGKKKTG 149
L EKN + ES + + L++K ++ K L +++ + EA GK+
Sbjct: 219 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP--QQQLQAEADHLGKELQS 276
Query: 150 GSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQ 209
S + + E + W R +++ + + ++ + ++ +++ + E+ +K E +
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEK--IREQE 334
Query: 210 KRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQE 269
++++ EE M + K R+E + + EK+ LE + ++E ++E HE+++
Sbjct: 335 EKMRRQEE---MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Query: 270 LKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRW 329
++ + R E+EK+ ++ + Q A +EE EE+ R
Sbjct: 392 IREQEEKRQ---------EEEKIR--------EQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Query: 330 EEARLGAASLKFGARDAASQEPKYQLVLEEEE 361
+E ++ K ++ +E K Q E+EE
Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQ---EQEE 463
Score = 48.1 bits (113), Expect = 4e-05
Identities = 48/224 (21%), Positives = 96/224 (42%), Gaps = 37/224 (16%)
Query: 85 REARALLEKNRSYRLLEDSEESS-----EETVSRAGSSLQKKRKKRKHLRKK-------- 131
R+ + E+ +R E E EE V R + + +K + +K
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 132 REEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERV-RQRDK 190
RE+EE+ ++Q EK ++E + + E++ + EE+ E++ RQ +K
Sbjct: 526 REQEEK-------------IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572
Query: 191 DRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAEL 250
R + R K+ E ++++ EE K +E + + + EK+ + E ++
Sbjct: 573 IREQEEKIREQKEKIREQEEKIWEQEE----------KIREQEEMMQEQEEKMWEQEEKM 622
Query: 251 ADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEA 294
++E + E ++E +++ VR +E + QE LEA
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
Score = 44.7 bits (104), Expect = 5e-04
Identities = 38/149 (25%), Positives = 69/149 (46%), Gaps = 13/149 (8%)
Query: 77 EKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEE 136
E+ R E + R EK R E+ + EE + +Q++ K R+ K RE+EE
Sbjct: 522 EEKIREQEEKIREQEEKIREQ---EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE 578
Query: 137 E-EEASEKGKKKTGGSKQQTEKPESEDE---------WERTERERLQDLEERDAFAERVR 186
+ E EK +++ +Q EK ++E WE+ E+ Q+ + ++ + R
Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 638
Query: 187 QRDKDRTRNVLERSDKKAYEEAQKRLKMA 215
Q +K + V R ++ +E Q+ L+ A
Sbjct: 639 QEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,837,013
Number of Sequences: 37866
Number of extensions: 1873363
Number of successful extensions: 30004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 493
Number of HSP's successfully gapped in prelim test: 1115
Number of HSP's that attempted gapping in prelim test: 11780
Number of HSP's gapped (non-prelim): 8188
length of query: 1041
length of database: 18,247,518
effective HSP length: 112
effective length of query: 929
effective length of database: 14,006,526
effective search space: 13012062654
effective search space used: 13012062654
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.