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Search of human proteins with 4503249
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
(375 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503249 DEK oncogene isoform 1 [Homo sapiens] 736 0.0
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 656 0.0
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 63 4e-10
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 63 4e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 61 2e-09
gi|4557509 cylicin 2 [Homo sapiens] 60 4e-09
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 59 5e-09
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 59 7e-09
gi|221219020 NYD-SP11 protein [Homo sapiens] 58 2e-08
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 57 3e-08
gi|104526627 triadin [Homo sapiens] 57 3e-08
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 57 3e-08
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 57 3e-08
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 57 4e-08
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 57 4e-08
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 55 8e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 55 1e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 55 1e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 55 1e-07
gi|168229156 NFKB activating protein [Homo sapiens] 54 2e-07
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 54 2e-07
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 54 2e-07
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 54 2e-07
gi|224591430 Ly1 antibody reactive homolog [Homo sapiens] 54 2e-07
gi|8923398 Ly1 antibody reactive homolog [Homo sapiens] 54 2e-07
gi|153791492 eukaryotic translation initiation factor 3, subunit... 54 3e-07
gi|83700233 eukaryotic translation initiation factor 3, subunit ... 54 3e-07
gi|4503525 eukaryotic translation initiation factor 3, subunit C... 54 3e-07
gi|122937227 U2-associated SR140 protein [Homo sapiens] 53 5e-07
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 52 7e-07
>gi|4503249 DEK oncogene isoform 1 [Homo sapiens]
Length = 375
Score = 736 bits (1900), Expect = 0.0
Identities = 375/375 (100%), Positives = 375/375 (100%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 60
MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK
Sbjct: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 60
Query: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV
Sbjct: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
Query: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL
Sbjct: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
Query: 181 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 240
NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK
Sbjct: 181 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 240
Query: 241 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 300
EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE
Sbjct: 241 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 300
Query: 301 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 360
SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT
Sbjct: 301 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 360
Query: 361 ERKDFIKTTVKELIS 375
ERKDFIKTTVKELIS
Sbjct: 361 ERKDFIKTTVKELIS 375
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 656 bits (1693), Expect = 0.0
Identities = 341/375 (90%), Positives = 341/375 (90%), Gaps = 34/375 (9%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 60
MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEK
Sbjct: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEK------------ 48
Query: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
GKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV
Sbjct: 49 ----------------------GKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 86
Query: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL
Sbjct: 87 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 146
Query: 181 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 240
NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK
Sbjct: 147 NFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNK 206
Query: 241 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 300
EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE
Sbjct: 207 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 266
Query: 301 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 360
SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT
Sbjct: 267 SESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 326
Query: 361 ERKDFIKTTVKELIS 375
ERKDFIKTTVKELIS
Sbjct: 327 ERKDFIKTTVKELIS 341
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 63.2 bits (152), Expect = 4e-10
Identities = 75/314 (23%), Positives = 125/314 (39%), Gaps = 35/314 (11%)
Query: 6 PAAEGEGTPTQ--PASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKV 63
P AE E + P PE+ E EEEE +++EEEE+E + EG EK
Sbjct: 499 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEK--- 555
Query: 64 ERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSL 123
E + + Q E T A+ +G+ E E ++K++E+ +L V+
Sbjct: 556 EGSSEKEEGEQEEGETEAEAEGE---EAEAKEEKKVEEKSEEVATKEEL-------VADA 605
Query: 124 KKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFL 183
K + + P K V+ K K + K KS +E G +
Sbjct: 606 KVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS----------- 654
Query: 184 MHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEES 243
P P K K SK +E+ S + + + + E+E+K +E+
Sbjct: 655 --PVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 712
Query: 244 SDDEDKESEEEPPKKTAKREKP----KQKATSK---SKKSVKSANVKKADSSTTKKNQNS 296
+E E +EE PK +++K K++A ++ KSVK K+ Q
Sbjct: 713 PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEK 772
Query: 297 SKKESESEDSSDDE 310
K+++ E S++E
Sbjct: 773 EKEKAGGEGGSEEE 786
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/180 (23%), Positives = 77/180 (42%), Gaps = 11/180 (6%)
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE---- 250
KS + GS+KE +S + + + E + ++EKK +E+S + KE
Sbjct: 544 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 603
Query: 251 -SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 309
++ E P+K AK PK K K V + V++ S K+ K +S S +
Sbjct: 604 DAKVEKPEK-AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 662
Query: 310 EPLIKKLKKPPTDEELKETIKK-----LLASANLEEVTMKQICKKVYENYPTYDLTERKD 364
E + K P +E+ K + K + A + + K+ +K + P + E+K+
Sbjct: 663 EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 722
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/131 (23%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 213 MARKAKRTKCPEILSDESSSDEDE---KKNKEESSDDEDKESEEEPPKKTAKREKPKQKA 269
++ K ++ + E +E ++E+E KK+ +++ E KE E E ++ + E+ ++
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 541
Query: 270 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETI 329
+KS ++ + + K+ S + Q + E+E+E +E K+ KK E T
Sbjct: 542 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG---EEAEAKEEKKVEEKSEEVATK 598
Query: 330 KKLLASANLEE 340
++L+A A +E+
Sbjct: 599 EELVADAKVEK 609
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 4/162 (2%)
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKC--PEILSDESSSDEDEKKNKEESSDDEDKESE 252
K + K + E +A K K PE+ +E +E+E + +EE D+ K +
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 547
Query: 253 EEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPL 312
E + K++ + ++ A ++A++ KK + S++ + E+ D +
Sbjct: 548 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 607
Query: 313 IK--KLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 352
K K K P ++E K + + +EE + K E
Sbjct: 608 EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 649
Score = 37.7 bits (86), Expect = 0.017
Identities = 69/342 (20%), Positives = 122/342 (35%), Gaps = 55/342 (16%)
Query: 8 AEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLT 67
+E E T E M ++E+ EE++E+ E EEEE K V+ + K E
Sbjct: 467 SEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGE 526
Query: 68 MQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNV 127
+ Q E +++ DE + S +K
Sbjct: 527 KEEEEGQEE-----------------------EEEEDEGAKSDQAEEGGSEKEGSSEKEE 563
Query: 128 GQFSGFPFEKGSVQYKKK-EEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHP 186
G+ E+G + + + EE K + + EV E ++++ K P
Sbjct: 564 GEQ-----EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK--------P 610
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246
+ + P+PKS + K K + ++ S + +E+
Sbjct: 611 EKAKSPVPKSP---------------VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 655
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
K EE K + ++KA S KS KA+ K + ++E E +++
Sbjct: 656 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAE---VGKGEQKEEEEKEVKEA 712
Query: 307 SDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICK 348
+E + KK +KP E K+ + A E VT+ + K
Sbjct: 713 PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 754
Score = 34.3 bits (77), Expect = 0.19
Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 229 ESSSDEDEKKNKEES--SDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKAD 286
E + EDEK EE+ + E+ + KK A EK ++ + + + K + VK
Sbjct: 458 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517
Query: 287 SSTTKKNQNSSKKESESEDSSDDE 310
++ ++E + E+ +DE
Sbjct: 518 PEVKEEEGEKEEEEGQEEEEEEDE 541
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 63.2 bits (152), Expect = 4e-10
Identities = 75/314 (23%), Positives = 125/314 (39%), Gaps = 35/314 (11%)
Query: 6 PAAEGEGTPTQ--PASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKV 63
P AE E + P PE+ E EEEE +++EEEE+E + EG EK
Sbjct: 123 PEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEK--- 179
Query: 64 ERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSL 123
E + + Q E T A+ +G+ E E ++K++E+ +L V+
Sbjct: 180 EGSSEKEEGEQEEGETEAEAEGE---EAEAKEEKKVEEKSEEVATKEEL-------VADA 229
Query: 124 KKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFL 183
K + + P K V+ K K + K KS +E G +
Sbjct: 230 KVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKS----------- 278
Query: 184 MHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEES 243
P P K K SK +E+ S + + + + E+E+K +E+
Sbjct: 279 --PVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 336
Query: 244 SDDEDKESEEEPPKKTAKREKP----KQKATSK---SKKSVKSANVKKADSSTTKKNQNS 296
+E E +EE PK +++K K++A ++ KSVK K+ Q
Sbjct: 337 PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEK 396
Query: 297 SKKESESEDSSDDE 310
K+++ E S++E
Sbjct: 397 EKEKAGGEGGSEEE 410
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/180 (23%), Positives = 77/180 (42%), Gaps = 11/180 (6%)
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE---- 250
KS + GS+KE +S + + + E + ++EKK +E+S + KE
Sbjct: 168 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227
Query: 251 -SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 309
++ E P+K AK PK K K V + V++ S K+ K +S S +
Sbjct: 228 DAKVEKPEK-AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 286
Query: 310 EPLIKKLKKPPTDEELKETIKK-----LLASANLEEVTMKQICKKVYENYPTYDLTERKD 364
E + K P +E+ K + K + A + + K+ +K + P + E+K+
Sbjct: 287 EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 346
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/131 (23%), Positives = 67/131 (51%), Gaps = 6/131 (4%)
Query: 213 MARKAKRTKCPEILSDESSSDEDE---KKNKEESSDDEDKESEEEPPKKTAKREKPKQKA 269
++ K ++ + E +E ++E+E KK+ +++ E KE E E ++ + E+ ++
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 165
Query: 270 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETI 329
+KS ++ + + K+ S + Q + E+E+E +E K+ KK E T
Sbjct: 166 GAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG---EEAEAKEEKKVEEKSEEVATK 222
Query: 330 KKLLASANLEE 340
++L+A A +E+
Sbjct: 223 EELVADAKVEK 233
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 4/162 (2%)
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKC--PEILSDESSSDEDEKKNKEESSDDEDKESE 252
K + K + E +A K K PE+ +E +E+E + +EE D+ K +
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171
Query: 253 EEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPL 312
E + K++ + ++ A ++A++ KK + S++ + E+ D +
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 231
Query: 313 IK--KLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYE 352
K K K P ++E K + + +EE + K E
Sbjct: 232 EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 273
Score = 37.7 bits (86), Expect = 0.017
Identities = 69/342 (20%), Positives = 122/342 (35%), Gaps = 55/342 (16%)
Query: 8 AEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLT 67
+E E T E M ++E+ EE++E+ E EEEE K V+ + K E
Sbjct: 91 SEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGE 150
Query: 68 MQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNV 127
+ Q E +++ DE + S +K
Sbjct: 151 KEEEEGQEE-----------------------EEEEDEGAKSDQAEEGGSEKEGSSEKEE 187
Query: 128 GQFSGFPFEKGSVQYKKK-EEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHP 186
G+ E+G + + + EE K + + EV E ++++ K P
Sbjct: 188 GEQ-----EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK--------P 234
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246
+ + P+PKS + K K + ++ S + +E+
Sbjct: 235 EKAKSPVPKSP---------------VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP 279
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
K EE K + ++KA S KS KA+ K + ++E E +++
Sbjct: 280 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAE---VGKGEQKEEEEKEVKEA 336
Query: 307 SDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICK 348
+E + KK +KP E K+ + A E VT+ + K
Sbjct: 337 PKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 378
Score = 34.3 bits (77), Expect = 0.19
Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 229 ESSSDEDEKKNKEES--SDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKAD 286
E + EDEK EE+ + E+ + KK A EK ++ + + + K + VK
Sbjct: 82 EETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141
Query: 287 SSTTKKNQNSSKKESESEDSSDDE 310
++ ++E + E+ +DE
Sbjct: 142 PEVKEEEGEKEEEEGQEEEEEEDE 165
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 60.8 bits (146), Expect = 2e-09
Identities = 71/323 (21%), Positives = 129/323 (39%), Gaps = 42/323 (13%)
Query: 20 EKEPEMPGPRE-ESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPF 78
E+E E RE E E E + + E E E E+E+ + KR++++ E + L+R+
Sbjct: 392 EREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLR 451
Query: 79 TIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQF-SGFPFEK 137
++L E +KKT E + R ++ K + +F + ++
Sbjct: 452 EKEAAYQERLKNWE----IRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDR 507
Query: 138 GSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSK 197
+Y + + K+ R+ + + D +R E +++ L HP P +
Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAE------ 561
Query: 198 KTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPK 257
M ++A+R + P+I + S +E+E+K ++E +E E EEEP +
Sbjct: 562 ------------LQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Query: 258 KTAKRE--KPKQKATSKSKKSVKSANVKKADSSTTK---KNQNSSKKESESE-------- 304
K + +P A S S S + D S ++NS ++ E
Sbjct: 610 KPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLS 669
Query: 305 -----DSSDDEPLIKKLKKPPTD 322
+S +P K KK P D
Sbjct: 670 LKLGASNSPGQPNSVKRKKLPVD 692
Score = 48.5 bits (114), Expect = 1e-05
Identities = 67/340 (19%), Positives = 142/340 (41%), Gaps = 37/340 (10%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFT 79
E+E E RE E E + + E E E+EKE+ E +RE+ + +R + R+
Sbjct: 311 ERERERERERERREREREREREREREKEKER----ERERERDR-DRDRTKERDRDRDRER 365
Query: 80 IAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGS 139
++ + + +K D R + ++ + E+
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERER------ERER 419
Query: 140 VQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELV--KRILNFLMHPKPSGKPLPKSK 197
+ +++E+ K+ R + E LER E +R+ N+ + + K++
Sbjct: 420 EREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK------KTR 473
Query: 198 KTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDE--DKESEEEP 255
+ + ++E MA++AKR K E L D +D K + + D+E E E
Sbjct: 474 EYEKEAEREEERRREMAKEAKRLK--EFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEA 531
Query: 256 PKKTAKREKP-----KQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDE 310
++ KREK +Q+ ++ A +++ + ++ Q K+E ESE+ +++
Sbjct: 532 DERDRKREKEELEEIRQRLLAEGHPD-PDAELQRMEQEAERRRQPQIKQEPESEEEEEEK 590
Query: 311 PLIKKLKKPPTDEE--------LKETIKKLLASANLEEVT 342
++ ++ P +EE LK T++ + ++ ++ +
Sbjct: 591 QEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSAS 630
Score = 37.0 bits (84), Expect = 0.029
Identities = 31/174 (17%), Positives = 75/174 (43%), Gaps = 11/174 (6%)
Query: 193 LPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSD---ESSSDEDEKKNKEESSDDEDK 249
+ K ++ + ++ER R+ +R + E + E D D + KE D + +
Sbjct: 305 IEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRE 364
Query: 250 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDD 309
+ ++++ R K + ++ KS+ + ++ + ++ + ++E E E +
Sbjct: 365 RDRDRDRERSSDRNKDRSRSREKSRDRERE---RERERERERERERERERERERERERER 421
Query: 310 EPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLTERK 363
E +K KK +E+ ++ ++ L E K+ + E +++ ERK
Sbjct: 422 EREREKDKKRDREEDEEDAYERRKLERKLRE---KEAAYQ--ERLKNWEIRERK 470
Score = 33.5 bits (75), Expect = 0.32
Identities = 30/156 (19%), Positives = 65/156 (41%), Gaps = 10/156 (6%)
Query: 162 EVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARK---AK 218
E LD E + +++K + L+ S P + KK+ + R+ A
Sbjct: 194 EALD-EETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAP 252
Query: 219 RTKCPEILSDESSSDEDEKKNKEESSD------DEDKESEEEPPKKTAKREKPKQKATSK 272
P I ++ ++ E E+ ++ S D K+ EEE KK +R++ +++ +
Sbjct: 253 LIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRER 312
Query: 273 SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 308
++ + ++ + ++ + +KE E E D
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERD 348
Score = 32.7 bits (73), Expect = 0.55
Identities = 16/37 (43%), Positives = 25/37 (67%), Gaps = 2/37 (5%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDE--EEEEEEKEK 50
QP ++EPE EE +E+E++ +E EEEEE ++K
Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 32.3 bits (72), Expect = 0.71
Identities = 17/58 (29%), Positives = 30/58 (51%)
Query: 8 AEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVER 65
AEG P E E R+ ++E E +EEEEE+++++ E E+++ E+
Sbjct: 552 AEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Score = 30.8 bits (68), Expect = 2.1
Identities = 16/37 (43%), Positives = 24/37 (64%), Gaps = 3/37 (8%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSL 52
+P SE+E E ++E EE+ +E EEEEE E++ L
Sbjct: 580 EPESEEEEE---EKQEKEEKREEPMEEEEEPEQKPCL 613
Score = 30.4 bits (67), Expect = 2.7
Identities = 21/101 (20%), Positives = 43/101 (42%), Gaps = 5/101 (4%)
Query: 229 ESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK-KSVKSANVKKADS 287
E + EK+ +E + ++E E E ++ +RE+ +++ + K K + + D
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351
Query: 288 STTKKNQNSSKKE----SESEDSSDDEPLIKKLKKPPTDEE 324
TK+ +E + E SSD + ++ D E
Sbjct: 352 DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRE 392
Score = 30.0 bits (66), Expect = 3.5
Identities = 13/42 (30%), Positives = 24/42 (57%)
Query: 6 PAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEE 47
P AE + + ++P++ E EEEE++ ++EE+ EE
Sbjct: 558 PDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREE 599
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/208 (25%), Positives = 91/208 (43%), Gaps = 15/208 (7%)
Query: 136 EKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPK 195
E+ SV + + LK R + S + ++ + G + K + K GK K
Sbjct: 86 ERPSVYLAARRQPLKPTRTVEVDS--KAAEIGKKGEDKTTQKDTTDSESELK-QGKKDSK 142
Query: 196 SKKTCSKGSKKERNSSGMARKAKRT------KCPEILSDESSSDEDEKKNKEESSDDEDK 249
K KG +++ ++ ++K K+ E ++ + +D KK+K++S+ +D
Sbjct: 143 KGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDS 202
Query: 250 ESEEEPPKK-TAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 308
+E E K T K K +K + K K S KAD + + + K ES+D+
Sbjct: 203 ATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKK 262
Query: 309 DEPLIKKLKK-----PPTDEELKETIKK 331
D IKK KK TD + K+ +KK
Sbjct: 263 DAKEIKKGKKDKKKPSSTDSDSKDDVKK 290
Score = 50.8 bits (120), Expect = 2e-06
Identities = 77/325 (23%), Positives = 132/325 (40%), Gaps = 41/325 (12%)
Query: 22 EPEMPGPREESEEEEDED------DEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQR 75
+P+ PG + S+ + D DEE+ ++ + L + R ++ + +R
Sbjct: 39 KPQRPGTKRRSKPSQIRDNTVSIIDEEQLRGDRRQPLWMY--RSLMRISERPSVYLAARR 96
Query: 76 EPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPF 135
+P K + E++ + KK D + K + + KK+ + G
Sbjct: 97 QPL-----KPTRTVEVDSKAAEIGKKGED--KTTQKDTTDSESELKQGKKDSKK--GKDI 147
Query: 136 EKGS---VQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKP 192
EKG + KK + KK S E D E+ G + K K S K
Sbjct: 148 EKGKEEKLDAKKDSKKGKKDAEKGKDSATESED-EKGGAKKDNKK-------DKKDSNKG 199
Query: 193 LPKSKKTCSKGSK--KERNSSGMARKAKRTKCPEI----LSDESSSDEDEKKNKEESSDD 246
K T S+G K E++S + +K+ K I + + DED KK+ + +
Sbjct: 200 --KDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDES 257
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
+D + + + KK K +K S SK VK K++ TK + +KK++E E S
Sbjct: 258 KDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVK----KESKKDATKDAKKVAKKDTEKE-S 312
Query: 307 SDDEPLIKKLKKPPTDEELKETIKK 331
+D + KK K ++ K+ KK
Sbjct: 313 ADSKKDAKKNAKKDAKKDAKKNAKK 337
Score = 44.3 bits (103), Expect = 2e-04
Identities = 31/110 (28%), Positives = 55/110 (50%), Gaps = 13/110 (11%)
Query: 197 KKTCSKG--SKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEE 254
KK +KG SK + + +K K+ K +D S D+ +K++K++++ D
Sbjct: 248 KKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDA------- 300
Query: 255 PPKKTAKREKPKQKATSK--SKKSVKSANVKKADSSTTKKNQNSSKKESE 302
KK AK++ K+ A SK +KK+ K K A + K + +KK+ +
Sbjct: 301 --KKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
Score = 35.4 bits (80), Expect = 0.084
Identities = 18/73 (24%), Positives = 37/73 (50%)
Query: 191 KPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE 250
K P S + SK K+ + + AK+ + + + S +D KKN ++ + + K+
Sbjct: 274 KKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKK 333
Query: 251 SEEEPPKKTAKRE 263
+ ++ KK AK++
Sbjct: 334 NAKKDEKKDAKKK 346
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 59.3 bits (142), Expect = 5e-09
Identities = 78/329 (23%), Positives = 139/329 (42%), Gaps = 58/329 (17%)
Query: 15 TQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLT--MQVSS 72
++ +SE+E E EE EEEE+E+DEEEEEEE+E+ E + + RLT V+
Sbjct: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE---EEENIQSSPPRLTKPQSVAI 1121
Query: 73 LQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQF-- 130
++ PF + + +G+K I S T+ + ++L N P S ++ + Q
Sbjct: 1122 KRKRPFVLKKKRGRKRRRIN------SSVTTETISETTEVL-NEPFDNSDEERPMPQLEP 1174
Query: 131 ----------------SGFPFEKGSVQYKKKEEMLKK--FRNAMLKSICEVLDLERSGVN 172
F + G + ++EE F+NA D R+ +N
Sbjct: 1175 TCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNA---------DPCRNNMN 1225
Query: 173 SELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRT--KCPEILSDES 230
+ N K + +PL K K+ KG+K+ S K ++T K E+
Sbjct: 1226 DD----SSNLKEGSKDNPEPL-KCKQVWPKGTKRGL-SKWRQNKERKTGFKLNLYTPPET 1279
Query: 231 SSDEDEKKNKEESSDDEDKESE------EEPPKKTAKREKPKQKATSKSKKSVKSANV-- 282
+ DE+ EE + + ++ EE K+T + P+++ + + S N
Sbjct: 1280 PMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSP 1339
Query: 283 -KKADSSTTKKNQNSSKKESESEDSSDDE 310
+K + K + ++E E E+ ++E
Sbjct: 1340 GEKPEDDLIKPEEEEEEEEEEEEEEEEEE 1368
Score = 47.4 bits (111), Expect = 2e-05
Identities = 83/402 (20%), Positives = 153/402 (38%), Gaps = 84/402 (20%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEE----------------KEKSLIVEGKREKKKV 63
E+E E EE EEEE+E++EEEEEE K K V K+ +K
Sbjct: 1078 EEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKR 1137
Query: 64 ERLTMQVSS--------LQREPFTIAQGKG-----QKLCEIERI-------------HFF 97
R+ V++ + EPF + + + CEIE H
Sbjct: 1138 RRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQP 1197
Query: 98 LSKKKTDE--------LRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEML 149
K++T+E +N N S+LK+ + + P + V K + L
Sbjct: 1198 GKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEG-SKDNPEPLKCKQVWPKGTKRGL 1256
Query: 150 KKFRNAMLKSICEVLDLERSGV-----NSELVKRILNFLMHPKPSGKPLPKSKKTCSKG- 203
K+R + L+L + ++ K S P+ ++ G
Sbjct: 1257 SKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGE 1316
Query: 204 -------SKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPP 256
+++E + ++ + PE D +E+E++ +EE ++E++E EEE
Sbjct: 1317 ALLPQEENRREETCAPVSPNTSPGEKPE--DDLIKPEEEEEEEEEEEEEEEEEEGEEEEG 1374
Query: 257 KKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKL 316
+++ K+ K + + +T+K ++ + E E+ D+EP +
Sbjct: 1375 GGNVEKDPDGAKSQEKEEPEI-----------STEKEDSARLDDHEEEEEEDEEPSHNE- 1422
Query: 317 KKPPTDEELKETIKKLLASANLE-EVTMKQICKKVYENYPTY 357
D + + + SA +E E ++ K+V EN T+
Sbjct: 1423 -----DHDADDEDDSHMESAEVEKEELPRESFKEVLENQETF 1459
Score = 45.8 bits (107), Expect = 6e-05
Identities = 46/216 (21%), Positives = 94/216 (43%), Gaps = 26/216 (12%)
Query: 143 KKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSK 202
+K+ E L + + K E+L + S + N +H P +P+ + +
Sbjct: 1005 EKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLH-SPESRPVTGERGQLLE 1063
Query: 203 GSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKR 262
SK+ + + + + E +E +EDE++ +EE ++E++ + PP+ T +
Sbjct: 1064 LSKES------SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
Query: 263 E---KPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKP 319
K K+ K K+ K + S TT+ +++ +E D+SD+E + +L+
Sbjct: 1118 SVAIKRKRPFVLKKKRGRKRRRIN--SSVTTETISETTEVLNEPFDNSDEERPMPQLE-- 1173
Query: 320 PTDEELKETIKKLLASANLEEVTMKQICKKVYENYP 355
PT E +EE K + +K +++ P
Sbjct: 1174 PTCE------------IEVEEDGRKPVLRKAFQHQP 1197
Score = 42.4 bits (98), Expect = 7e-04
Identities = 18/36 (50%), Positives = 26/36 (72%)
Query: 15 TQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEK 50
T P + E ++ P EE EEEE+E++EEEEEE +E+
Sbjct: 1337 TSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1372
Score = 38.1 bits (87), Expect = 0.013
Identities = 32/136 (23%), Positives = 65/136 (47%), Gaps = 14/136 (10%)
Query: 198 KTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKE-----ESSDDEDKESE 252
KTCS+ ++ + +S P ++S+ + S+E+ + KE E + +KE +
Sbjct: 972 KTCSRANELDPDSLRWT--------PILISNAAVSEEEREAEKEAERLMEQASCWEKEEQ 1023
Query: 253 EEPPKKTAKREKP-KQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEP 311
E + R+ P K ++ +K S +S V + ++ SS++E E ED ++E
Sbjct: 1024 EILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEE 1083
Query: 312 LIKKLKKPPTDEELKE 327
++ + +EE +E
Sbjct: 1084 EEEEEEDEEEEEEEEE 1099
Score = 32.7 bits (73), Expect = 0.55
Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 3/69 (4%)
Query: 4 SAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKV 63
++P + E +P E+E E EE EEEE+E +EEE EK +EK++
Sbjct: 1337 TSPGEKPEDDLIKPEEEEEEE---EEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEP 1393
Query: 64 ERLTMQVSS 72
E T + S
Sbjct: 1394 EISTEKEDS 1402
Score = 31.2 bits (69), Expect = 1.6
Identities = 24/111 (21%), Positives = 50/111 (45%), Gaps = 9/111 (8%)
Query: 228 DESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQ--KATSKSKKSVKSANVKKA 285
+E DE+ N++ +DDED E + K E P++ K +++++ NV+
Sbjct: 1410 EEEEEDEEPSHNEDHDADDEDDSHMES--AEVEKEELPRESFKEVLENQETFLDLNVQPG 1467
Query: 286 DSS-----TTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 331
S+ + +S E + D E + + ++PP E+ ++ +K
Sbjct: 1468 HSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQK 1518
Score = 28.9 bits (63), Expect = 7.9
Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 10 GEGTPTQPASEKEPEMPGPREESEEEED---EDDEEEEEEEKEKS 51
G P K E P +E+E+ +D EEEEEE++E S
Sbjct: 1375 GGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPS 1419
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 58.9 bits (141), Expect = 7e-09
Identities = 83/381 (21%), Positives = 144/381 (37%), Gaps = 42/381 (11%)
Query: 15 TQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQ 74
++ +SE PE + S+ +D ++ + +K + + K KK ++ S
Sbjct: 175 SKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKK----DLKRSKTS 230
Query: 75 REPFTIAQGK-----------GQKLCEIERIHFFLSKKKTDELRN--LHKLLYNRPGTVS 121
+P + + GQ E +L + +N L Y + T
Sbjct: 231 NDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKK 290
Query: 122 SLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSEL--VKRI 179
+ KK+ S + K K+ + K + +K E D E E K+
Sbjct: 291 NAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKD 350
Query: 180 LNFLMHP--KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEK 237
L K K P+S T S +K RN S +KA S ++D+K
Sbjct: 351 KKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKA-------------SKNDDKK 397
Query: 238 KNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK-------KADSSTT 290
K+ ++ + D ESE E + +K K+ + + +KKSVK+ K DS
Sbjct: 398 KDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKG 457
Query: 291 KKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKV 350
KK++ KK+S+ +D D + + +D ELK+ K ++ K K
Sbjct: 458 KKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDT 517
Query: 351 YENYPTYDLTERKDFIKTTVK 371
+D + + F KT+ K
Sbjct: 518 ESTDAEFDESSKTGF-KTSTK 537
Score = 40.4 bits (93), Expect = 0.003
Identities = 35/139 (25%), Positives = 63/139 (45%), Gaps = 15/139 (10%)
Query: 195 KSKKTCSKGSKKERNSSGMARK-----AKRTKCPEILSDESSSDEDEKKNKEESSDDEDK 249
K KT +K S K S A +K+ K E + S +D+KK+ +++++ +
Sbjct: 427 KDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEM 486
Query: 250 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNS-----SKKESESE 304
ES+ E K++K K SKK +K K +S+ + +++S + + +
Sbjct: 487 ESDLE-----LKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGS 541
Query: 305 DSSDDEPLIKKLKKPPTDE 323
D+ +E L K K DE
Sbjct: 542 DTESEESLYKPGAKKKIDE 560
Score = 39.3 bits (90), Expect = 0.006
Identities = 62/308 (20%), Positives = 125/308 (40%), Gaps = 40/308 (12%)
Query: 8 AEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKE-KSLIVEGKREKKKVERL 66
AE E + K+ + +++ +++ +D E + E + K + K++KKK+++
Sbjct: 298 AESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKD 357
Query: 67 TMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKN 126
+ + + T + K + + + K D+ ++ K+ ++ S L+
Sbjct: 358 DKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSE-SELES- 415
Query: 127 VGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHP 186
K S + +KK++ K N KS+ D E + +SE P
Sbjct: 416 ----------KESQKDEKKDKKDSKTDNK--KSVKN--DEESTDADSE-----------P 450
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILS---------DESSSDEDEK 237
K K K +K K SKK+ + A+ T+ L ++ S +D K
Sbjct: 451 KGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIK 510
Query: 238 KNKEESSDDEDKESEEEPPKKTAKREKPKQKAT-SKSKKSVKSANVKKADSSTTKKNQNS 296
K+ + ++ D E +E KT + K K + ++S++S+ KK + + NS
Sbjct: 511 KDARKDTESTDAEFDES--SKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANS 568
Query: 297 SKKESESE 304
+ ES+
Sbjct: 569 KMEGLESK 576
Score = 38.1 bits (87), Expect = 0.013
Identities = 34/136 (25%), Positives = 61/136 (44%), Gaps = 7/136 (5%)
Query: 215 RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 274
+KA+ K + + +KK +++ E K+ EE K+ + +K K++ +++
Sbjct: 111 KKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENE 170
Query: 275 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTD-EELKETIKKLL 333
+S KS K+ S T ++QNS K S D+ K KK T+ K KK L
Sbjct: 171 QSKKS----KSSSETNPESQNS--KTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDL 224
Query: 334 ASANLEEVTMKQICKK 349
+ + +IC +
Sbjct: 225 KRSKTSNDPISEICSE 240
Score = 34.7 bits (78), Expect = 0.14
Identities = 50/213 (23%), Positives = 82/213 (38%), Gaps = 39/213 (18%)
Query: 190 GKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDE--SSSDEDEKKNKEESSDDE 247
G PL K K KG N ++TK SS E+E+ K +SS +
Sbjct: 124 GTPLKKDSK--KKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSET 181
Query: 248 DKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE--SED 305
+ ES+ +K K+ + + K + + + K K+++ S+ SE SE+
Sbjct: 182 NPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSEN 241
Query: 306 S-----------SDDEPL------------------IKKLKKPPTDEELKETIKKLLASA 336
S SDDE + +K K T ++ K+ KK +
Sbjct: 242 SLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKY--TKKDTKKNAKKSSDAE 299
Query: 337 NLEEVTMKQICKKVYENYPTYDLTERKDFIKTT 369
+ + K+ KKV +N D ++KD K T
Sbjct: 300 SEDSKDAKKDSKKVKKNVKKDD--KKKDVKKDT 330
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 57.8 bits (138), Expect = 2e-08
Identities = 58/283 (20%), Positives = 125/283 (44%), Gaps = 30/283 (10%)
Query: 58 REKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRP 117
R+++K+ + ++++ ++R F + + +++ + S+K+++ ++ KL +
Sbjct: 2085 RDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQR 2144
Query: 118 GTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVL--DLERSGVNSEL 175
+ +++ + KEE + + + + + EV+ D E G+ E
Sbjct: 2145 KLANKMRRMIN----------------KEEKMTEEESKLARKHSEVILDDEEEGGIEEEE 2188
Query: 176 V----KRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESS 231
V KR K KP K + +E S M + E LS E
Sbjct: 2189 VIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEE 2248
Query: 232 SDEDEKKNKEESS---DDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSS 288
+ +E++ +EE ++E+++ EEE +K ++E+ ++K K KK K V++ +
Sbjct: 2249 EEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKK---KKKKEKKKEEVQEKEEV 2305
Query: 289 TTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 331
+K + S++E+ES SD+E + + KE +KK
Sbjct: 2306 FEEKEEIMSEEETES--LSDEEEEEESCSLEEEVDREKEILKK 2346
Score = 40.8 bits (94), Expect = 0.002
Identities = 22/55 (40%), Positives = 31/55 (56%)
Query: 11 EGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVER 65
E ++ E+E E EE EEE+E EEEE EEK+ E K++KKK ++
Sbjct: 2241 ESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKK 2295
Score = 40.0 bits (92), Expect = 0.003
Identities = 67/321 (20%), Positives = 127/321 (39%), Gaps = 49/321 (15%)
Query: 29 REESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQV----SSLQREPFTIAQGK 84
++ES+ ++ D + EK+ I EG + ++ +T +V + RE AQ K
Sbjct: 1295 KKESKVLLEDLDWDVVPPEKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQ-AQKK 1353
Query: 85 GQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKK 144
+ + +E L K K K+++ PG V+ K+ + F+K Q +K
Sbjct: 1354 ARDMLGLEETQVILKKGK--------KVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRK 1405
Query: 145 -----------KEEMLKKFRNAMLKSICEVLDLERSGVNSE----LVKRILNFLMHPKP- 188
K EM K+ R+ M + + E+ LE V E +++R ++ K
Sbjct: 1406 AVQKERKVGKIKREMTKEERD-MSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAW 1464
Query: 189 -SGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEES---- 243
K + + K K+E + + K + E LS E +++KK K E
Sbjct: 1465 DEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQV 1524
Query: 244 --------------SDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSST 289
D+E+ EEE ++ ++E+ + ++ K A + + +
Sbjct: 1525 WENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARA 1584
Query: 290 TKKNQNSSKKESESEDSSDDE 310
KK +K ++ E+ E
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQE 1605
Score = 39.3 bits (90), Expect = 0.006
Identities = 20/45 (44%), Positives = 30/45 (66%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVE 64
E+E E REE EE ++E++ EE++ EKE+ + K+EKKK E
Sbjct: 2254 EEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEE 2298
Score = 38.5 bits (88), Expect = 0.010
Identities = 20/59 (33%), Positives = 34/59 (57%)
Query: 18 ASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQRE 76
+SE+E E E EEE E++EE +EEE+ + VE + E+KK ++ + +Q +
Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302
Score = 37.7 bits (86), Expect = 0.017
Identities = 75/350 (21%), Positives = 138/350 (39%), Gaps = 38/350 (10%)
Query: 47 EKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDEL 106
++EK+L +E KR ++ RL +L + T + +K+ ++E+ F K +E
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGE-TPETSRQRKMTQVEQ-ELFERKLSLEEK 2015
Query: 107 RNLH--KLLYNRPGTVSSLKKNVGQFSGF------PFEKGSVQYKKKEEMLKKFR---NA 155
LH ++L ++ K + K S + KK E L K N
Sbjct: 2016 ILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNK 2075
Query: 156 MLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCS------KGSKKERN 209
+LK++ ++ ER E+ + + K + +SK K S+ ++
Sbjct: 2076 ILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKD 2135
Query: 210 SSGMARKAKR--TKCPEILSDESSSDEDEKKNKEESS-----DDEDKESEEEPPKKTAKR 262
+ARK ++ K +++ E E+E K + S D+E+ EEE KR
Sbjct: 2136 EKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKR 2195
Query: 263 EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTD 322
K+K K+ D K + + ESE S + E L+ +L+K +
Sbjct: 2196 RWRKRK------------EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESL 2243
Query: 323 EELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLTERKDFIKTTVKE 372
+E ++ EEV ++ +K E + + ++ K KE
Sbjct: 2244 SSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293
Score = 37.0 bits (84), Expect = 0.029
Identities = 51/201 (25%), Positives = 89/201 (44%), Gaps = 33/201 (16%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEE--EEEEKEKSLIVEGKREKKKVERLTMQVSSLQRE- 76
EK+ + EE EEE+E +EEE EEEE+ K E + E+K+VE+ + ++E
Sbjct: 2238 EKQESLSSEEEEEREEEEEREEEEVREEEEERKE---EEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 77 PFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFE 136
Q K + E E I +S+++T+ L + SL++ V +
Sbjct: 2295 KKEEVQEKEEVFEEKEEI---MSEEETESLSD-----EEEEEESCSLEEEVDR------- 2339
Query: 137 KGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS-----------GVNSELVKRILNFLMH 185
+ + K+K+ L++ R L+ VL + R GV +K++++ +
Sbjct: 2340 EKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALE 2399
Query: 186 PKPSGKPLPKSKKTCSKGSKK 206
K P+P +K S KK
Sbjct: 2400 MKEK-TPVPVPEKQISWEDKK 2419
Score = 37.0 bits (84), Expect = 0.029
Identities = 42/165 (25%), Positives = 73/165 (44%), Gaps = 17/165 (10%)
Query: 4 SAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKR----E 59
S + E E + E+E E EEEE E+ + E+EEE++K E K+ E
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301
Query: 60 KKKVERLTMQVSSLQREPFTIAQGKGQKLC----EIERIHFFLSKKKTDELR-NLHKLLY 114
K++V ++ S + + + ++ C E++R L K+K +L+ K L
Sbjct: 2302 KEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLR 2361
Query: 115 NRPGTVSSLKKNVGQFSGFPFEKG-SVQYKKKEEMLKKFRNAMLK 158
R +S L+ G P KG +++ + LKK + L+
Sbjct: 2362 GRERVLSILR-------GVPHGKGRAIRLGVLKSPLKKLMSTALE 2399
Score = 35.4 bits (80), Expect = 0.084
Identities = 54/236 (22%), Positives = 101/236 (42%), Gaps = 26/236 (11%)
Query: 144 KKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKS--KKTCS 201
+ +E++ + K ++L LE + V + K+++ GK + K KKT
Sbjct: 1338 RHKEVMPREEEQAQKKARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQ 1397
Query: 202 KGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAK 261
K K+ R + RK + K + + + D + EE + E+K ++E +
Sbjct: 1398 KSPKQGRKAVQKERKVGKIK-----REMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIE 1452
Query: 262 REKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPT 321
R P + K+ K + T+K+ + K+E E ++E L + +K
Sbjct: 1453 RT-PSWQDWKKAWDEWKQVH------GETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSP 1505
Query: 322 DEELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLTER--KDFIKTTVKELIS 375
+EE+ + KKL EE K+V+EN + E+ KD + T++E +S
Sbjct: 1506 EEEMLQEDKKL----KWEE------WKQVWENMLSSKSKEQQYKDEEEVTLEEEVS 1551
Score = 35.4 bits (80), Expect = 0.084
Identities = 82/392 (20%), Positives = 159/392 (40%), Gaps = 53/392 (13%)
Query: 15 TQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQ 74
T+ A E+E + + ++ +E +EEE K + LI + + +K ER + L
Sbjct: 1768 TKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELT 1827
Query: 75 REPFTIAQGK--GQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSG 132
+ + Q K Q+ + + L+++K + L N +L +++ V +K +G F+
Sbjct: 1828 KNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLV-QVKNKLGMFNK 1886
Query: 133 F-----------------------PFEKGSVQYK----KKEEML--KKFRNAMLKSICEV 163
EK VQ + KK+E L +K + A+ K++ +
Sbjct: 1887 ILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQG 1946
Query: 164 LDLERSGVNSELVKRILNFLMHPKPSGK-PLPKSKKTCSKGSKKERNSSGMARKAKRTKC 222
R ++ ++ LN M K L + K+T SKG E +R+ K T+
Sbjct: 1947 KKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPE-----TSRQRKMTQV 2001
Query: 223 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVK-SAN 281
+ L + S E+ K +D EE ++ K K + T + V+
Sbjct: 2002 EQELFERKLSLEE----KILLHEDRILAMEE------SEIAKGKLEFTRGQRIFVQGQRK 2051
Query: 282 VKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEV 341
+ KA KK ++ SK+ ++ + + ++ T EE+K T K +
Sbjct: 2052 LAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRL 2111
Query: 342 TMKQICKKVYENYPTYDLTERKDFIKTTVKEL 373
+++Q + E +D +E++ + K+L
Sbjct: 2112 SIEQSKLDIKE----WDFSEKRSELTKDEKKL 2139
Score = 33.9 bits (76), Expect = 0.24
Identities = 73/348 (20%), Positives = 134/348 (38%), Gaps = 66/348 (18%)
Query: 21 KEPEMPGPREESEEEEDEDDEEEEE-EEKEKSLIVEGKREKKKVERLTMQVSSLQREPFT 79
+E E+ EE E + +E +EEE ++E L+ E K+ ++ E L Q L E
Sbjct: 1710 QEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETK 1769
Query: 80 IAQGKGQKLCEIERI----------HFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQ 129
+AQ + + E E++ L +K+ + KL R ++S+++
Sbjct: 1770 LAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELT-- 1827
Query: 130 FSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPS 189
+ + Y+KK +K A K +L +R N L +
Sbjct: 1828 ------KNKMILYQKKNLAQEKKNLAQEK--------------EKLAQRKENLLYN---- 1863
Query: 190 GKPLPKSKKTCSKGSKKE-RNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDED 248
K + T SK + +N GM K + +EK +E+ + +
Sbjct: 1864 -----KERLTHSKKQLVQVKNKLGMFNKI-------------LAQVEEKLTQEKETVIKK 1905
Query: 249 KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSD 308
KE E KK + E S +KK K A K + Q + E + + +
Sbjct: 1906 KEKLAETEKKLVQVE------DSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKE 1959
Query: 309 DEPLIKKLKKPPTDE----ELKETIKKLLASANLEEVTMKQICKKVYE 352
++ L ++K+ ++ E KET+ K + M Q+ ++++E
Sbjct: 1960 EKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFE 2007
Score = 32.7 bits (73), Expect = 0.55
Identities = 17/45 (37%), Positives = 29/45 (64%), Gaps = 4/45 (8%)
Query: 24 EMPGPREESEEEE----DEDDEEEEEEEKEKSLIVEGKREKKKVE 64
EM +E E++E +E++E EEEEE+E+ + E + E+K+ E
Sbjct: 2229 EMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273
Score = 31.6 bits (70), Expect = 1.2
Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 11/136 (8%)
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246
K S K L KKT + SK+ G+ T+ I +E+S +
Sbjct: 1091 KHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKLS 1150
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE--SE 304
+D +S+E+ K T K + ++ KKA + KK KE++ +E
Sbjct: 1151 KDVDSQEKDISKD------HIALTLKRLQKIRDKRDKKATAQKLKKKHKKKGKEAKVINE 1204
Query: 305 DSSD---DEPLIKKLK 317
+++ ++P+ KK+K
Sbjct: 1205 ETTPPVMEQPVTKKVK 1220
Score = 31.2 bits (69), Expect = 1.6
Identities = 60/305 (19%), Positives = 118/305 (38%), Gaps = 31/305 (10%)
Query: 29 REESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKL 88
RE E+E+ +E+ +E+ K + KR + + +R + L +E +AQ + Q
Sbjct: 1552 REGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKR-AQEERKLAQEEEKLAQEERQLA 1610
Query: 89 CEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEM 148
E ++ K D+ + + G + ++ + Q EK S + +K +
Sbjct: 1611 QEERKLAQAYVKITQDD-----REMAQAEGKFAQKEETLAQRG----EKLSQEAEKLAQK 1661
Query: 149 LKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKER 208
KK K E L + G VK IL + P ++E+
Sbjct: 1662 RKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELP----------------QREQ 1705
Query: 209 NSSGMARK-AKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQ 267
N ++ A+ + E +E S E+E +E +E K+ EE +REK +
Sbjct: 1706 NLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSE 1765
Query: 268 KATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKE 327
+ T K + + + +++ +E E ++ + KK+K E
Sbjct: 1766 EET----KLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWIN 1821
Query: 328 TIKKL 332
++++L
Sbjct: 1822 SMEEL 1826
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 57.0 bits (136), Expect = 3e-08
Identities = 70/332 (21%), Positives = 139/332 (41%), Gaps = 51/332 (15%)
Query: 20 EKEPEMPGPREES--EEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREP 77
EK+ E+ +++ + + E+ + +EEEEK + + K EKKK+E + Q +
Sbjct: 176 EKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMND- 234
Query: 78 FTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEK 137
+L + E+I K+ + +RNLH E+
Sbjct: 235 ---------ELYKEEKIWKEKFKQHEEYIRNLH----------------------LQMEE 263
Query: 138 GSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSK 197
++K ++E K +N++LK +++ ++ + F+ + K P+ K +
Sbjct: 264 ERTRFKDQQE---KEKNSLLK--------QQNNAAVKIQAKYKAFVAYQKYG--PIIKEQ 310
Query: 198 KTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPK 257
K +E + K + + L +E E+ KK KEE +KE EE+ K
Sbjct: 311 IESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEK--K 368
Query: 258 KTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLK 317
K+E +++ SK K ++ ++ S+ K + K ED S+D+ I K
Sbjct: 369 NIVKQE--REQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNL 426
Query: 318 KPPTDEELKETIKKLLASANLEEVTMKQICKK 349
++ ++ + L+ +N++E +Q K
Sbjct: 427 VDENSKKQEDVLLWLVEESNMKENVDRQTILK 458
Score = 37.4 bits (85), Expect = 0.022
Identities = 69/343 (20%), Positives = 132/343 (38%), Gaps = 49/343 (14%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTM 68
E + Q EKE ++ EE+ + +E+ +EE +K+K E KR +K+ E
Sbjct: 312 ESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKE--EERKRREKEYE---- 365
Query: 69 QVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVG 128
E I + + ++L E+I L + + +L +SS K G
Sbjct: 366 -------EKKNIVKQEREQLISKEKI--ILREDASQQL------------IISSALKKSG 404
Query: 129 ------QFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNF 182
+KG + +E KK + +L + E +++ + ++K +
Sbjct: 405 YNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLL-WLVEESNMKENVDRQTILKESIQV 463
Query: 183 LMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEE 242
+ S +T K E + +A+K +C E L + E+ E
Sbjct: 464 KLKES-------ISSQTILADFKMEEKNENLAKK----RCSEELVKQERKYENTDNKTEL 512
Query: 243 SSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE 302
+ D +E+ P + K + K++ K K V + N + NQ S+ ++
Sbjct: 513 GNSDLKGNLKEQFPLQELKSDAQKEE---KIMKHVINENTGQKTQIILGHNQEISEVKTN 569
Query: 303 SEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 345
E + KK++K EE++E L + +++KQ
Sbjct: 570 EEQKIIKDNQQKKIQK-VEKEEIQEQNGLLYKDKDTLVISVKQ 611
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 57.0 bits (136), Expect = 3e-08
Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 13/148 (8%)
Query: 225 ILSDESSSDEDEKKNKEESSDDEDKESEEEPP--------KKTAKREKPKQKATSKSKKS 276
+LSD SS+++E ++ +D DK +EPP KT K+EKP++K +K
Sbjct: 109 LLSDIISSEDEED---DDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHK 165
Query: 277 VKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASA 336
K +K + + + K++ E ++ + + L K+ KK T E+ +E KK +
Sbjct: 166 EKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGG 225
Query: 337 NLEEVTMKQICKKVYENYPTYDLTERKD 364
E+V KQ KV E T + K+
Sbjct: 226 KQEKV--KQTAAKVKEVQKTPSKPKEKE 251
Score = 52.0 bits (123), Expect = 9e-07
Identities = 83/353 (23%), Positives = 147/353 (41%), Gaps = 51/353 (14%)
Query: 13 TPTQPASEKEPEMPGPREESEEEEDEDDEEEEEE------EKEKSLIVEGKREKKKVE-- 64
TP PA E E G ++++E++ + +++E+E EKE ++ VE K K E
Sbjct: 303 TPASPALE---EKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETK 359
Query: 65 ----RLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRP--- 117
++ Q ++ + E ++ K +K E+E+ K K E + H P
Sbjct: 360 QGTVKIAAQAAAKKDEKKEDSK-KTKKPAEVEQ-----PKGKKQEKKEKHVEPAKSPKKE 413
Query: 118 GTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVK 177
+V S K+ + E G+V KK K+ + K++ + + E+SG S ++K
Sbjct: 414 HSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT--KTVEQEIRKEKSGKTSSILK 471
Query: 178 RILNFLMHP-KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDE 236
P K + +P S K +KK+ S A K + K P++ + E +
Sbjct: 472 D-----KEPIKGKEEKVPASLKEKEPETKKDEKMS-KAGKEVKPKPPQLQGKKEEKPEPQ 525
Query: 237 KKNKEESSDDEDKESEEE---PPKKTAKREKPKQKATSKSKKSVKSANVKK-ADSSTTKK 292
K + + + E + ++ P+KT KP++K K VK+ ++K A TKK
Sbjct: 526 IKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVL----KQVKAVTIEKTAKPKPTKK 581
Query: 293 NQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 345
+E + P IK K PT + E + + E K+
Sbjct: 582 ----------AEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKE 624
Score = 51.2 bits (121), Expect = 1e-06
Identities = 79/357 (22%), Positives = 140/357 (39%), Gaps = 37/357 (10%)
Query: 30 EESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLC 89
E+ + +ED D E +E K I + K EK++ +Q +E +GK +K+
Sbjct: 120 EDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEK---EKGK-EKVR 175
Query: 90 EIERIH------FFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYK 143
E E+ + KK+ E + L K S +K + G EK
Sbjct: 176 EKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAA 235
Query: 144 KKEEMLKKFRNAMLKSICEVLDLERSGVNSE-------LVKRILNFLMHP--KPSGKPLP 194
K +E+ K K D E++ V+ + +++ +H KP P
Sbjct: 236 KVKEVQKTPSKPKEKE-----DKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAI 290
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEE 254
+ S+ S + K K +++ + E +KK KE+ +KE+ +
Sbjct: 291 PPPLPTEQASRPTPASPALEEKEGEKK----KAEKKVTSETKKKEKEDIKKKSEKETAID 346
Query: 255 PPKK-TAKREKPKQKATSKSKKSVKSANVKKADSSTTKK----NQNSSKKESESEDSSDD 309
KK K + KQ + ++ + KK DS TKK Q KK+ + E +
Sbjct: 347 VEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEP 406
Query: 310 EPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQIC--KKVYENYPTYDLTERKD 364
KK P+D+++K ++ A + V++K+ KK + T + RK+
Sbjct: 407 AKSPKKEHSVPSDKQVKAKTER--AKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKE 461
Score = 46.6 bits (109), Expect = 4e-05
Identities = 69/343 (20%), Positives = 140/343 (40%), Gaps = 38/343 (11%)
Query: 11 EGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQV 70
+G +P K+ E+ E+ E + + +EKEK E REK+K E+
Sbjct: 130 KGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKG--KEKVREKEKPEKKATHK 187
Query: 71 SSLQR--EPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVG 128
+++ +P T K QK + + +K++E + ++ + V V
Sbjct: 188 EKIEKKEKPETKTLAKEQKKAK--------TAEKSEE-KTKKEVKGGKQEKVKQTAAKVK 238
Query: 129 QFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKP 188
+ P + + K+K + K + ++D+ V+ +L + P P
Sbjct: 239 EVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDI---FVHGDLKPGQSPAIPPPLP 295
Query: 189 ---SGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEI--LSDESSSDEDEKKNKEES 243
+ +P P S K +K++ + + K+ + +I S++ ++ + EKK ++
Sbjct: 296 TEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKA 355
Query: 244 SD---------------DEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSS 288
S+ ++K+ + + KK A+ E+PK K K +K V+ A K + S
Sbjct: 356 SETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHS 415
Query: 289 TTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 331
Q +K E E+ IKK +E+ +T+++
Sbjct: 416 VPSDKQVKAKTERAKEEIG--AVSIKKAVPGKKEEKTTKTVEQ 456
Score = 43.5 bits (101), Expect = 3e-04
Identities = 67/328 (20%), Positives = 137/328 (41%), Gaps = 22/328 (6%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 60
++A A A + E ++K E+ P+ + +E++++ E + +KE S + K+ K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHS-VPSDKQVK 423
Query: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIER-IHFFLSKKKTDELRNLHKLLYNRPGT 119
K ER ++ ++ + + + + +E+ I S K + L++ +
Sbjct: 424 AKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKV 483
Query: 120 VSSLKKNVGQFS-GFPFEKGSVQYKKKEEMLKKFRNA----MLKSICEVLDLERSGVNSE 174
+SLK+ + K + K K L+ + +K + E+ ++ +
Sbjct: 484 PASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQ 543
Query: 175 LVKRILNFLMHPKPSGKPLPKSKK-TCSKGSKKERNSSGMARKAK----RTKCPEILSDE 229
+ + + H KP K L + K T K +K + R+ + +T P+
Sbjct: 544 DIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKG 603
Query: 230 SSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKAD--S 287
+S + K K E S+ KES+E+ K + EK S K+S++ NV KA+ +
Sbjct: 604 TSEVTESGKKKTEISE---KESKEKADMKHLREEK-----VSTRKESLQLHNVTKAEKPA 655
Query: 288 STTKKNQNSSKKESESEDSSDDEPLIKK 315
+K ++ + E + D P +K
Sbjct: 656 RVSKDVEDVPASKKAKEGTEDVSPTKQK 683
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 57.0 bits (136), Expect = 3e-08
Identities = 70/332 (21%), Positives = 139/332 (41%), Gaps = 51/332 (15%)
Query: 20 EKEPEMPGPREES--EEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREP 77
EK+ E+ +++ + + E+ + +EEEEK + + K EKKK+E + Q +
Sbjct: 176 EKQKELEDKEKQTLKAQRDREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMND- 234
Query: 78 FTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEK 137
+L + E+I K+ + +RNLH E+
Sbjct: 235 ---------ELYKEEKIWKEKFKQHEEYIRNLH----------------------LQMEE 263
Query: 138 GSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSK 197
++K ++E K +N++LK +++ ++ + F+ + K P+ K +
Sbjct: 264 ERTRFKDQQE---KEKNSLLK--------QQNNAAVKIQAKYKAFVAYQKYG--PIIKEQ 310
Query: 198 KTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPK 257
K +E + K + + L +E E+ KK KEE +KE EE+ K
Sbjct: 311 IESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKEEERKRREKEYEEK--K 368
Query: 258 KTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLK 317
K+E +++ SK K ++ ++ S+ K + K ED S+D+ I K
Sbjct: 369 NIVKQE--REQLISKEKIILREDASQQLIISSALKKSGYNNKHLSLEDISNDKGDIAKNL 426
Query: 318 KPPTDEELKETIKKLLASANLEEVTMKQICKK 349
++ ++ + L+ +N++E +Q K
Sbjct: 427 VDENSKKQEDVLLWLVEESNMKENVDRQTILK 458
Score = 37.4 bits (85), Expect = 0.022
Identities = 69/343 (20%), Positives = 132/343 (38%), Gaps = 49/343 (14%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTM 68
E + Q EKE ++ EE+ + +E+ +EE +K+K E KR +K+ E
Sbjct: 312 ESKKRKAQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKE--EERKRREKEYE---- 365
Query: 69 QVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVG 128
E I + + ++L E+I L + + +L +SS K G
Sbjct: 366 -------EKKNIVKQEREQLISKEKI--ILREDASQQL------------IISSALKKSG 404
Query: 129 ------QFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNF 182
+KG + +E KK + +L + E +++ + ++K +
Sbjct: 405 YNNKHLSLEDISNDKGDIAKNLVDENSKKQEDVLL-WLVEESNMKENVDRQTILKESIQV 463
Query: 183 LMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEE 242
+ S +T K E + +A+K +C E L + E+ E
Sbjct: 464 KLKES-------ISSQTILADFKMEEKNENLAKK----RCSEELVKQERKYENTDNKTEL 512
Query: 243 SSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE 302
+ D +E+ P + K + K++ K K V + N + NQ S+ ++
Sbjct: 513 GNSDLKGNLKEQFPLQELKSDAQKEE---KIMKHVINENTGQKTQIILGHNQEISEVKTN 569
Query: 303 SEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 345
E + KK++K EE++E L + +++KQ
Sbjct: 570 EEQKIIKDNQQKKIQK-VEKEEIQEQNGLLYKDKDTLVISVKQ 611
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 57.0 bits (136), Expect = 3e-08
Identities = 44/158 (27%), Positives = 70/158 (44%), Gaps = 21/158 (13%)
Query: 191 KPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE 250
K L KS++ G++ +K K+ C S SSS D + +S D+E K+
Sbjct: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCR---SSSSSSSSDSSSSSSDSEDEEKKQ 127
Query: 251 SEEEPPKKTAKREKPKQKAT----SKSKKSVKSANVKKADSSTTKKNQNSSKK------- 299
+ KK + K Q +T S+SK+SVK K ++ K ++ SKK
Sbjct: 128 GKRRKKKKN-RSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPD 186
Query: 300 ------ESESEDSSDDEPLIKKLKKPPTDEELKETIKK 331
ES SE +++ KK ++ E+ KE +KK
Sbjct: 187 DKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK 224
Score = 55.5 bits (132), Expect = 8e-08
Identities = 45/163 (27%), Positives = 80/163 (49%), Gaps = 21/163 (12%)
Query: 179 ILNFLMHPKPSGKPLPKSKKTCSKGSK-----KERNSSGMARKAKRTKCPEILSDESSSD 233
I ++L P+P+ + + K + GSK +E+ + ++ ++++ + +ESSS
Sbjct: 30 IQDYLNRPRPTWEEVKKQLENKKTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSK 89
Query: 234 EDEKKNKEE-----------SSDDEDKESE-EEPPKKTAKREKPKQKATSKSKKSVKSAN 281
+ E+K K + SSD S+ E+ KK KR K K+ + KS +S S +
Sbjct: 90 KRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQS--STH 147
Query: 282 VKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEE 324
+++S + K + SK E+E E D L KK KK D++
Sbjct: 148 ESESESKESVKKKKKSKDETEKE--KDVRSLSKKRKKSYPDDK 188
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/179 (24%), Positives = 67/179 (37%), Gaps = 23/179 (12%)
Query: 138 GSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSK 197
G+ KK E KK + +S + S +S+ K GK K K
Sbjct: 83 GNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDE-------EKKQGKRRKKKK 135
Query: 198 KTCSKGSKK-----ERNSSGMARKAKRTKCPEILSDESSSDED----EKKNKEESSDDED 248
K S+ E S +K K++K DE+ ++D KK K+ DD+
Sbjct: 136 NRSYKSSQSSTHESESESKESVKKKKKSK------DETEKEKDVRSLSKKRKKSYPDDKP 189
Query: 249 KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSS 307
SE + + K+K + ++ K VKK KK+ KK+S S S
Sbjct: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKE-KVKKKKKKQHKKHSKKKKKKSGSSHKS 247
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 56.6 bits (135), Expect = 4e-08
Identities = 74/308 (24%), Positives = 124/308 (40%), Gaps = 27/308 (8%)
Query: 33 EEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIE 92
+E E E ++E E EKEK + K K+++R +E F + +E
Sbjct: 635 KEREKEKHKKEIEGEKEK---YKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNME 691
Query: 93 RIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKF 152
L KK KL N S+ +K+V + F E+ + K+E K F
Sbjct: 692 HESLTLEKKS--------KLEKNIKDDKSTKEKHVSKERNFKEERDKI----KKESEKSF 739
Query: 153 RNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSG 212
R +K + E + + +SE L + G L + + K K + S
Sbjct: 740 REEKIKDLKEERENIPTDKDSEFTS--LGMSAIEESIGLHLVEKEIDIEKQEKHIKESKE 797
Query: 213 MARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREK----PKQK 268
K + K +I E + E EKK K E ++DK E K +++K +K
Sbjct: 798 KPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEK 857
Query: 269 ATSKSKKSVKSANVKKAD---SSTTKKNQNSSKKESESE---DSSDDEPLIKKLKKPPTD 322
+ +KS +A +KK D S K ++ K++ E E S ++ L++K K +
Sbjct: 858 CHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDN 917
Query: 323 EELKETIK 330
E ++ K
Sbjct: 918 SEYSKSEK 925
Score = 43.5 bits (101), Expect = 3e-04
Identities = 80/375 (21%), Positives = 156/375 (41%), Gaps = 53/375 (14%)
Query: 24 EMPGPREESEEEEDEDDEEEEEEEKEKSLIV-------EGKREKKKVERLTMQVSSLQRE 76
++ + E +E + ++E +E + +L V E RE+ +
Sbjct: 452 KLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLH 511
Query: 77 PFTIAQGKGQK-LCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVS-SLKKNVGQF---- 130
F I+ GK K C LS+K++ L+ H PG+ SL+ ++ ++
Sbjct: 512 LFHISTGKSPKHSCG-------LSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTE 564
Query: 131 SGFPFEKGSVQ---YKKKEEMLKKFR-------NAMLKSICEVLDLERSGVNSELVKRIL 180
S F E SV+ +K+K + K F NA +K E S + + +
Sbjct: 565 SEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEG 624
Query: 181 NFLMHPKPSGKPLPKSK-KTCSKGSKKERNSSGMARKAKRT-------------KCPE-- 224
L K K K K K +G K++ + A++ +R+ K E
Sbjct: 625 KTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETE 684
Query: 225 --ILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 282
L+ E S EKK+K E + +DK ++E+ K ++ + K +S+KS + +
Sbjct: 685 DLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKI 744
Query: 283 K-----KADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASAN 337
K + + T K ++ +S S E+S + K++ ++ +KE+ +K +
Sbjct: 745 KDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQ 804
Query: 338 LEEVTMKQICKKVYE 352
++E ++++ +K +E
Sbjct: 805 IKEKDIEKMERKTFE 819
Score = 38.5 bits (88), Expect = 0.010
Identities = 75/344 (21%), Positives = 135/344 (39%), Gaps = 39/344 (11%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEE----EEDEDDEEEEEEEKEKSLIVEGKREKKKVE 64
E E PT SE EES E++ D E++E+ KE E + + K+ +
Sbjct: 750 ERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKD 809
Query: 65 RLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLK 124
M+ + ++E + K +K +++ K+ D+L + H ++ G S
Sbjct: 810 IEKMERKTFEKEKKIKHEHKSEK-DKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKS--- 865
Query: 125 KNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLM 184
KN +K + K +E+M +K D E+ L + LM
Sbjct: 866 KNTAAI-----KKTDDREKSREKMDRKH------------DKEKPEKERHLAESKEKHLM 908
Query: 185 HPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESS 244
K + K+ KG KE++ + +K K I S ++EKK+
Sbjct: 909 EKKNKQSDNSEYSKS-EKGKNKEKDRE-LDKKEKSRDKESINITNSKHIQEEKKSSIVDG 966
Query: 245 DDED-------KESEEEPPKKT--AKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN 295
+ KE ++ P KT K + K K + K+ K + + +S K++
Sbjct: 967 NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEA 1026
Query: 296 SSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLE 339
K S S D P K K+ D+ ++ + +++L+ +LE
Sbjct: 1027 DKPKPKSSPASKDTRP---KEKRLVNDDLMQTSFERMLSLKDLE 1067
Score = 36.6 bits (83), Expect = 0.038
Identities = 67/309 (21%), Positives = 127/309 (41%), Gaps = 30/309 (9%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEE---EEKEKSLIVEGKREKKKVER 65
EGE + A +K + RE+ + + D++ E+E E KEK L+ EKK +
Sbjct: 861 EGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLM-----EKKNKQS 915
Query: 66 LTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKK 125
+ S ++ GK + E+ K+K+ + +++ + N K
Sbjct: 916 DNSEYSKSEK-------GKNK-----EKDRELDKKEKSRDKESIN--ITNSKHIQEEKKS 961
Query: 126 NVGQFSGFPFEKG-SVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLM 184
++ + EK S++ K K+E LK + +D + + +I + L
Sbjct: 962 SIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLK 1021
Query: 185 HPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDED-EKKNKEES 243
+ KP PKS KE+ + +T +LS + E KK+KE+
Sbjct: 1022 LKSEADKPKPKSSPASKDTRPKEKRL--VNDDLMQTSFERMLSLKDLEIEQWHKKHKEKI 1079
Query: 244 SDDEDKESEEEPPKKTAKREKPKQKAT---SKSKKSVKSANVKKADSSTTKKN-QNSSKK 299
E + + ++K K K T SK+K+ +S + + D+ T +K +++
Sbjct: 1080 KQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN 1139
Query: 300 ESESEDSSD 308
S+S D+ +
Sbjct: 1140 RSQSVDTKN 1148
Score = 35.0 bits (79), Expect = 0.11
Identities = 68/309 (22%), Positives = 116/309 (37%), Gaps = 55/309 (17%)
Query: 36 EDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQ--VSSLQREPFTIAQGKGQKLCEIER 93
+D+ +E+ KE++ E + KK+ E+ + + L+ E I K +
Sbjct: 708 KDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTS--- 764
Query: 94 IHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK-F 152
L +E LH L + + +K++ + P ++ ++ K E+M +K F
Sbjct: 765 ----LGMSAIEESIGLH--LVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTF 818
Query: 153 RNAML-----KSICEVLDLERSGVNSELVKRILN----FLMHPKPSGKPLPKSKKTCS-- 201
KS + LDL SE V +I + H + K KSK T +
Sbjct: 819 EKEKKIKHEHKSEKDKLDL------SECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIK 872
Query: 202 KGSKKERNSSGMARKAKRTKCPEI------------------LSDESSSDEDEK-KNKEE 242
K +E++ M RK + K PE SD S + EK KNKE+
Sbjct: 873 KTDDREKSREKMDRKHDKEK-PEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEK 931
Query: 243 SSD------DEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNS 296
+ DKES K + EK + K ++K+ K +
Sbjct: 932 DRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDG 991
Query: 297 SKKESESED 305
+K+ + +D
Sbjct: 992 KEKDKKDKD 1000
Score = 33.1 bits (74), Expect = 0.42
Identities = 68/326 (20%), Positives = 129/326 (39%), Gaps = 48/326 (14%)
Query: 34 EEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIER 93
E +D+DDEE + ++ ++ + +R++ + E + + Q + F K +K + R
Sbjct: 339 EFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQ-KPSR 397
Query: 94 IHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFR 153
+ + S + +DE +K + + + Q G ++K+K ++ +K +
Sbjct: 398 V-LYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSG--EHKQKGKVKRKLK 454
Query: 154 NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGS--------- 204
N + L E+ G + RI N ++ L S+KT +G+
Sbjct: 455 NQNKNKENQELKQEKEGKEN---TRITNLTVN-----TGLDCSEKTREEGNFRKSFSPKD 506
Query: 205 ------------KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESE 252
K ++S G++ K E S E + + ++ ESE
Sbjct: 507 DTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESE 566
Query: 253 EEPPKKTAKREKPKQKATSKSKKSV-------KSANVKKADSSTTKKNQNSSKKESESED 305
P + K K K+K SK +K +A +K D S T +N + + K+ + E
Sbjct: 567 FLPESSSVKSCKHKEK--SKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEG 624
Query: 306 SSDDEPLIKKLKKPPTDEELKETIKK 331
+ +KK K + E KE KK
Sbjct: 625 KT-----LKKHKLKHKERE-KEKHKK 644
Score = 32.3 bits (72), Expect = 0.71
Identities = 37/151 (24%), Positives = 57/151 (37%), Gaps = 17/151 (11%)
Query: 184 MHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAK---RTKCPEILSDESSSDEDEKKNK 240
M KP G+ + SK K ER+ K K + K P +S +N+
Sbjct: 21 MVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPS--------RNE 72
Query: 241 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 300
E SD E +E P KK K+E +K+T S + +K + + + +
Sbjct: 73 ERDSDTE----KEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPD 128
Query: 301 SESEDSSDDEPLIKKLKKPPTDEELKETIKK 331
S S P K K P + K+ + K
Sbjct: 129 STPNHPSQTTPAQK--KTPSSSSRQKDKVNK 157
Score = 28.9 bits (63), Expect = 7.9
Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 2/80 (2%)
Query: 241 EESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKK--NQNSSK 298
+ + D D E+P + +K + T K ++S S +K+ S K + S+
Sbjct: 11 QSENSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSR 70
Query: 299 KESESEDSSDDEPLIKKLKK 318
E D+ + P KK KK
Sbjct: 71 NEERDSDTEKEGPEKKKTKK 90
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 56.6 bits (135), Expect = 4e-08
Identities = 74/308 (24%), Positives = 124/308 (40%), Gaps = 27/308 (8%)
Query: 33 EEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIE 92
+E E E ++E E EKEK + K K+++R +E F + +E
Sbjct: 658 KEREKEKHKKEIEGEKEK---YKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNME 714
Query: 93 RIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKF 152
L KK KL N S+ +K+V + F E+ + K+E K F
Sbjct: 715 HESLTLEKKS--------KLEKNIKDDKSTKEKHVSKERNFKEERDKI----KKESEKSF 762
Query: 153 RNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSG 212
R +K + E + + +SE L + G L + + K K + S
Sbjct: 763 REEKIKDLKEERENIPTDKDSEFTS--LGMSAIEESIGLHLVEKEIDIEKQEKHIKESKE 820
Query: 213 MARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREK----PKQK 268
K + K +I E + E EKK K E ++DK E K +++K +K
Sbjct: 821 KPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEK 880
Query: 269 ATSKSKKSVKSANVKKAD---SSTTKKNQNSSKKESESE---DSSDDEPLIKKLKKPPTD 322
+ +KS +A +KK D S K ++ K++ E E S ++ L++K K +
Sbjct: 881 CHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDN 940
Query: 323 EELKETIK 330
E ++ K
Sbjct: 941 SEYSKSEK 948
Score = 43.5 bits (101), Expect = 3e-04
Identities = 80/375 (21%), Positives = 156/375 (41%), Gaps = 53/375 (14%)
Query: 24 EMPGPREESEEEEDEDDEEEEEEEKEKSLIV-------EGKREKKKVERLTMQVSSLQRE 76
++ + E +E + ++E +E + +L V E RE+ +
Sbjct: 475 KLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLH 534
Query: 77 PFTIAQGKGQK-LCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVS-SLKKNVGQF---- 130
F I+ GK K C LS+K++ L+ H PG+ SL+ ++ ++
Sbjct: 535 LFHISTGKSPKHSCG-------LSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTE 587
Query: 131 SGFPFEKGSVQ---YKKKEEMLKKFR-------NAMLKSICEVLDLERSGVNSELVKRIL 180
S F E SV+ +K+K + K F NA +K E S + + +
Sbjct: 588 SEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEG 647
Query: 181 NFLMHPKPSGKPLPKSK-KTCSKGSKKERNSSGMARKAKRT-------------KCPE-- 224
L K K K K K +G K++ + A++ +R+ K E
Sbjct: 648 KTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETE 707
Query: 225 --ILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 282
L+ E S EKK+K E + +DK ++E+ K ++ + K +S+KS + +
Sbjct: 708 DLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKI 767
Query: 283 K-----KADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASAN 337
K + + T K ++ +S S E+S + K++ ++ +KE+ +K +
Sbjct: 768 KDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQ 827
Query: 338 LEEVTMKQICKKVYE 352
++E ++++ +K +E
Sbjct: 828 IKEKDIEKMERKTFE 842
Score = 38.5 bits (88), Expect = 0.010
Identities = 75/344 (21%), Positives = 135/344 (39%), Gaps = 39/344 (11%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEE----EEDEDDEEEEEEEKEKSLIVEGKREKKKVE 64
E E PT SE EES E++ D E++E+ KE E + + K+ +
Sbjct: 773 ERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKD 832
Query: 65 RLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLK 124
M+ + ++E + K +K +++ K+ D+L + H ++ G S
Sbjct: 833 IEKMERKTFEKEKKIKHEHKSEK-DKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKS--- 888
Query: 125 KNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLM 184
KN +K + K +E+M +K D E+ L + LM
Sbjct: 889 KNTAAI-----KKTDDREKSREKMDRKH------------DKEKPEKERHLAESKEKHLM 931
Query: 185 HPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESS 244
K + K+ KG KE++ + +K K I S ++EKK+
Sbjct: 932 EKKNKQSDNSEYSKS-EKGKNKEKDRE-LDKKEKSRDKESINITNSKHIQEEKKSSIVDG 989
Query: 245 DDED-------KESEEEPPKKT--AKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN 295
+ KE ++ P KT K + K K + K+ K + + +S K++
Sbjct: 990 NKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEA 1049
Query: 296 SSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLE 339
K S S D P K K+ D+ ++ + +++L+ +LE
Sbjct: 1050 DKPKPKSSPASKDTRP---KEKRLVNDDLMQTSFERMLSLKDLE 1090
Score = 36.6 bits (83), Expect = 0.038
Identities = 67/309 (21%), Positives = 127/309 (41%), Gaps = 30/309 (9%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEE---EEKEKSLIVEGKREKKKVER 65
EGE + A +K + RE+ + + D++ E+E E KEK L+ EKK +
Sbjct: 884 EGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLM-----EKKNKQS 938
Query: 66 LTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKK 125
+ S ++ GK + E+ K+K+ + +++ + N K
Sbjct: 939 DNSEYSKSEK-------GKNK-----EKDRELDKKEKSRDKESIN--ITNSKHIQEEKKS 984
Query: 126 NVGQFSGFPFEKG-SVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLM 184
++ + EK S++ K K+E LK + +D + + +I + L
Sbjct: 985 SIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLK 1044
Query: 185 HPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDED-EKKNKEES 243
+ KP PKS KE+ + +T +LS + E KK+KE+
Sbjct: 1045 LKSEADKPKPKSSPASKDTRPKEKRL--VNDDLMQTSFERMLSLKDLEIEQWHKKHKEKI 1102
Query: 244 SDDEDKESEEEPPKKTAKREKPKQKAT---SKSKKSVKSANVKKADSSTTKKN-QNSSKK 299
E + + ++K K K T SK+K+ +S + + D+ T +K +++
Sbjct: 1103 KQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSN 1162
Query: 300 ESESEDSSD 308
S+S D+ +
Sbjct: 1163 RSQSVDTKN 1171
Score = 35.0 bits (79), Expect = 0.11
Identities = 68/309 (22%), Positives = 116/309 (37%), Gaps = 55/309 (17%)
Query: 36 EDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQ--VSSLQREPFTIAQGKGQKLCEIER 93
+D+ +E+ KE++ E + KK+ E+ + + L+ E I K +
Sbjct: 731 KDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTS--- 787
Query: 94 IHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKK-F 152
L +E LH L + + +K++ + P ++ ++ K E+M +K F
Sbjct: 788 ----LGMSAIEESIGLH--LVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTF 841
Query: 153 RNAML-----KSICEVLDLERSGVNSELVKRILN----FLMHPKPSGKPLPKSKKTCS-- 201
KS + LDL SE V +I + H + K KSK T +
Sbjct: 842 EKEKKIKHEHKSEKDKLDL------SECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIK 895
Query: 202 KGSKKERNSSGMARKAKRTKCPEI------------------LSDESSSDEDEK-KNKEE 242
K +E++ M RK + K PE SD S + EK KNKE+
Sbjct: 896 KTDDREKSREKMDRKHDKEK-PEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEK 954
Query: 243 SSD------DEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNS 296
+ DKES K + EK + K ++K+ K +
Sbjct: 955 DRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDG 1014
Query: 297 SKKESESED 305
+K+ + +D
Sbjct: 1015 KEKDKKDKD 1023
Score = 33.1 bits (74), Expect = 0.42
Identities = 68/326 (20%), Positives = 129/326 (39%), Gaps = 48/326 (14%)
Query: 34 EEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLCEIER 93
E +D+DDEE + ++ ++ + +R++ + E + + Q + F K +K + R
Sbjct: 362 EFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQ-KPSR 420
Query: 94 IHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFR 153
+ + S + +DE +K + + + Q G ++K+K ++ +K +
Sbjct: 421 V-LYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSG--EHKQKGKVKRKLK 477
Query: 154 NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGS--------- 204
N + L E+ G + RI N ++ L S+KT +G+
Sbjct: 478 NQNKNKENQELKQEKEGKEN---TRITNLTVN-----TGLDCSEKTREEGNFRKSFSPKD 529
Query: 205 ------------KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESE 252
K ++S G++ K E S E + + ++ ESE
Sbjct: 530 DTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESE 589
Query: 253 EEPPKKTAKREKPKQKATSKSKKSV-------KSANVKKADSSTTKKNQNSSKKESESED 305
P + K K K+K SK +K +A +K D S T +N + + K+ + E
Sbjct: 590 FLPESSSVKSCKHKEK--SKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEG 647
Query: 306 SSDDEPLIKKLKKPPTDEELKETIKK 331
+ +KK K + E KE KK
Sbjct: 648 KT-----LKKHKLKHKERE-KEKHKK 667
Score = 30.0 bits (66), Expect = 3.5
Identities = 34/162 (20%), Positives = 57/162 (35%), Gaps = 16/162 (9%)
Query: 184 MHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAK---RTKCPEILSDESSSDEDEKKNK 240
M KP G+ + SK K ER+ K K + K P +S + + D +
Sbjct: 21 MVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEERDSDTDS 80
Query: 241 EESSDDED-----------KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSST 289
+ E+ +E P KK K+E +K+T S + +K +
Sbjct: 81 DPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALL 140
Query: 290 TKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKK 331
+ + +S S P K K P + K+ + K
Sbjct: 141 MQMTARDNSPDSTPNHPSQTTPAQK--KTPSSSSRQKDKVNK 180
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 55.5 bits (132), Expect = 8e-08
Identities = 54/193 (27%), Positives = 86/193 (44%), Gaps = 12/193 (6%)
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEE---S 243
KP+ KPLP K+ K SK+E + K P++ S E + +K K E S
Sbjct: 546 KPAAKPLPS--KSVRKESKEETPEVTKVNHVE--KPPKVESKEKVMVKKDKPIKTETKPS 601
Query: 244 SDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES 303
+++ S+EEP K E +++AT K+ K VKK + + +K +
Sbjct: 602 VTEKEVPSKEEP--SPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE 659
Query: 304 EDSSDDEPLIKKLKKPPTDE---ELKETIKKLLASANLEEVTMKQICKKVYENYPTYDLT 360
+D+ IKK +KP +E E+K+ IKK +EV + K+V + +
Sbjct: 660 VAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKK 719
Query: 361 ERKDFIKTTVKEL 373
E K K KE+
Sbjct: 720 EVKKEEKEPKKEI 732
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/185 (25%), Positives = 80/185 (43%), Gaps = 11/185 (5%)
Query: 167 ERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEIL 226
E S V +E+ ++ + K + K K + K+E+ K K P
Sbjct: 612 EPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKK 671
Query: 227 SDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKAD 286
++ +E +K+ K+E +E KE PKK K+E P ++ + KK K VKK +
Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKE-----PKKEVKKETPPKEVKKEVKKEEKK-EVKKEE 725
Query: 287 SSTTKKNQNSSK--KESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMK 344
K+ + K K+S + S +P K K P +E +K K +A+ +E
Sbjct: 726 KEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVK---KDSVAAGKPKEKGKI 782
Query: 345 QICKK 349
++ KK
Sbjct: 783 KVIKK 787
Score = 47.8 bits (112), Expect = 2e-05
Identities = 39/148 (26%), Positives = 70/148 (47%), Gaps = 8/148 (5%)
Query: 186 PKPSGKPLP-KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSD--EDEKKNKEE 242
P + K +P K + + K E+ ++ + KA + K + + D E+++K K+E
Sbjct: 600 PSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE 659
Query: 243 SSDDEDKE--SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 300
+ EDK +EE PKK +++ K++ + KK K K+ KK KKE
Sbjct: 660 VAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKK---EVKKE 716
Query: 301 SESEDSSDDEPLIKKLKKPPTDEELKET 328
+ E +++ K++KK P D + T
Sbjct: 717 EKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Score = 42.4 bits (98), Expect = 7e-04
Identities = 49/232 (21%), Positives = 98/232 (42%), Gaps = 17/232 (7%)
Query: 99 SKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLK 158
SK++T E+ ++ + +P V S K+ V P + + ++E+ K + +K
Sbjct: 561 SKEETPEVTKVNHV--EKPPKVES-KEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVK 617
Query: 159 SICEVLDLERSGVNSELVK-RILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKA 217
+ EV + + + V + K + + KP K K K K+++ K
Sbjct: 618 A--EVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKP 675
Query: 218 KRTKCPEILSDESSSDEDEKKNKEESSD----DEDKESEEEPPKKTAKREKPKQKATSKS 273
K+ + + + E +E ++ KE + + KE ++E K+ K EK +K K
Sbjct: 676 KKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKL 735
Query: 274 KKSVKSANVKKADSS-------TTKKNQNSSKKESESEDSSDDEPLIKKLKK 318
K K ++ +++ K + S KK+S + ++ IK +KK
Sbjct: 736 PKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKK 787
Score = 40.4 bits (93), Expect = 0.003
Identities = 67/334 (20%), Positives = 136/334 (40%), Gaps = 27/334 (8%)
Query: 9 EGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLT- 67
E + P + ++KE + P +EE ++E+ E ++E +KE E K KK+V++ T
Sbjct: 651 EEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKE-----EKKEPKKEVKKETP 705
Query: 68 ---MQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKT--DELRNLHKLLYNRPGTVSS 122
++ + E + + + + EI+++ K T E + L P S
Sbjct: 706 PKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEES 765
Query: 123 LKKNVGQFSGFPFEKGSVQYKKKEEMLKKF------RNAMLKSICEVLDLERSGVNSELV 176
+KK+ +G P EKG ++ KKE + A ++ + G EL
Sbjct: 766 VKKD-SVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKEL- 823
Query: 177 KRILNFLMHPKPSGKPLPKSKK---TCSKGSKKERNSSGMARKAKRTKCPE--ILSDESS 231
+ + + P+ K + K +K K + K K T+ E ++ E
Sbjct: 824 EAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKERE 883
Query: 232 SDEDEKKNKEESSDDEDKESE-EEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTT 290
+ ++ +E + E E E+ P++ E KQ K + A +++ +
Sbjct: 884 VTKGPAESPDEGITTTEGEGECEQTPEELEPVE--KQGVDDIEKFEDEGAGFEESSETGD 941
Query: 291 KKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEE 324
+ + +++ E E+ ++ + K PT++E
Sbjct: 942 YEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDE 975
Score = 38.5 bits (88), Expect = 0.010
Identities = 79/381 (20%), Positives = 148/381 (38%), Gaps = 52/381 (13%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKE-----KSLIVEGKR------EKKKVE 64
+P E + E P P+E +E + E+ +E ++EEKE K L + K+ E KK
Sbjct: 695 EPKKEVKKETP-PKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPA 753
Query: 65 RLTMQVSSLQR--EPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSS 122
L +V + + ++A GK ++ +I+ I KK + T ++
Sbjct: 754 ALKPKVPKKEESVKKDSVAAGKPKEKGKIKVI------KKEGKAAEAVAAAVGTGATTAA 807
Query: 123 LKKNVGQFSGFPFEKGSVQ---YKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRI 179
+ G + P ++ + E++ K F + + D++ EL++
Sbjct: 808 VMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQ---LELIEDE 864
Query: 180 LNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKC---PEILS-------DE 229
L +P + + ++ +KG E G+ +C PE L D+
Sbjct: 865 EK-LKETEPVEAYVIQKEREVTKGPA-ESPDEGITTTEGEGECEQTPEELEPVEKQGVDD 922
Query: 230 SSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSST 289
EDE EESS+ D E + E T + E+P++ S + + + S
Sbjct: 923 IEKFEDEGAGFEESSETGDYEEKAE----TEEAEEPEEDGEEHVCVSASKHSPTEDEESA 978
Query: 290 TKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKK 349
+ +++ ES S DD +E++ E I+K A + EE + +
Sbjct: 979 KAEADAYIREKRESVASGDDR----------AEEDMDEAIEKGEAEQSEEEADEEDKAED 1028
Query: 350 VYENYPTYDLTERKDFIKTTV 370
E + E +D++ V
Sbjct: 1029 AREEEYEPEKMEAEDYVMAVV 1049
Score = 35.8 bits (81), Expect = 0.064
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 223 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANV 282
PE L+ E + + KK+ +E K ++P KT K P +K+ KSK S
Sbjct: 2222 PEALAIEQNLGKALKKDLKE------KTKTKKPGTKT-KSSSPVKKSDGKSKPLAASPKP 2274
Query: 283 KKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASAN 337
S+ K ++ +S K+ ES + + ++K +E+ KET ASA+
Sbjct: 2275 AGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASAS 2329
Score = 34.7 bits (78), Expect = 0.14
Identities = 31/136 (22%), Positives = 55/136 (40%), Gaps = 6/136 (4%)
Query: 163 VLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKC 222
++D E + L K + L + KP K+K S + S G ++ +
Sbjct: 2219 MVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKS-----SSPVKKSDGKSKPLAASPK 2273
Query: 223 PEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAK-REKPKQKATSKSKKSVKSAN 281
P L + S K++ S ++ + P K A+ EK K+ + + + KSA
Sbjct: 2274 PAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAK 2333
Query: 282 VKKADSSTTKKNQNSS 297
A TTK ++S+
Sbjct: 2334 TATAGPGTTKTTKSSA 2349
Score = 33.1 bits (74), Expect = 0.42
Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 2/116 (1%)
Query: 190 GKPLPKS--KKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDE 247
GK L K +KT +K + SS +K+ P S + + ++ + +
Sbjct: 2232 GKALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPK 2291
Query: 248 DKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES 303
KES E+ K T E + K K++ +AN + S+ T + K ++S
Sbjct: 2292 KKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKS 2347
Score = 30.0 bits (66), Expect = 3.5
Identities = 64/301 (21%), Positives = 116/301 (38%), Gaps = 52/301 (17%)
Query: 44 EEEEKEKSLIVEGKREKKKVERLTMQVSSLQRE--PFTIAQGKGQKLCEIERIHFFLSKK 101
+E E E+SL+ + K E L + + ++ P +KL E E + ++ +K
Sbjct: 821 KELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQK 880
Query: 102 KTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRN--AMLKS 159
+ R + K P + + G+ P E V+ K+ + ++KF + A +
Sbjct: 881 E----REVTKGPAESPDEGITTTEGEGECEQTPEELEPVE-KQGVDDIEKFEDEGAGFEE 935
Query: 160 ICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAK- 218
E D E E + P+ G+ + C SK + KA+
Sbjct: 936 SSETGDYEEKAETEEAEE--------PEEDGE-----EHVCVSASKHSPTEDEESAKAEA 982
Query: 219 ----RTKCPEILSDESSSDED--------EKKNKEESSDDEDK-----ESEEEPPKKTAK 261
R K + S + ++ED E + EE +D+EDK E E EP K A+
Sbjct: 983 DAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAE 1042
Query: 262 R------EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE------SESEDSSDD 309
+K + ++ + + K+ + + + SS + SESE ++ D
Sbjct: 1043 DYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESEATASD 1102
Query: 310 E 310
E
Sbjct: 1103 E 1103
Score = 30.0 bits (66), Expect = 3.5
Identities = 36/176 (20%), Positives = 58/176 (32%), Gaps = 38/176 (21%)
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246
K G+ ++ T S + S + + + +CP I +D + EDE +
Sbjct: 2136 KQQGRQCDETPPTSVSESAPSQTDSDVPPETE--ECPSITADANIDSEDESETIPTDKTV 2193
Query: 247 EDKESEEEPPKKTAKREKPKQ---------------------KATSKSKKSVKSANVKKA 285
K + P + P+ K K K K K
Sbjct: 2194 TYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTK 2253
Query: 286 DSSTTKKNQNSSK------KESESEDSSD---------DEPLIKKLKKPPTDEELK 326
SS KK+ SK K + ++SSD + ++K KP T E+K
Sbjct: 2254 SSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVK 2309
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 55.1 bits (131), Expect = 1e-07
Identities = 84/356 (23%), Positives = 153/356 (42%), Gaps = 31/356 (8%)
Query: 5 APAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVE 64
A AAE EG A E+EP+ +++ E+++ + DE++ +E E+ L +E + K E
Sbjct: 21 ALAAEIEGAGA--AKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEAQGIKADRE 77
Query: 65 RLTMQVSSLQREPFTIA--QGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSS 122
+ ++ + E FT + KGQK KK++ + + +L + +
Sbjct: 78 TVAVKPTENNEEEFTSKDKKKKGQK-----------GKKQSFDDNDSEELEDKDSKSKKT 126
Query: 123 LKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLD-----LERSGVNS--EL 175
K V +SG + + KK + + N E D ERS +NS E
Sbjct: 127 AKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGES 186
Query: 176 VKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDED 235
FL K K K+K + S E + + K K E E ++
Sbjct: 187 GDESDEFLQSRKGQKKN-QKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDE 245
Query: 236 EKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKS----ANVKKADSSTTK 291
EK + + E+ E+ ++ K + ++ ++ T KSK +V + A+ +KA++ T
Sbjct: 246 EKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAA 305
Query: 292 K--NQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 345
+ N+ KK+ + + + E K+ KK P+ +K +++ LA EE K+
Sbjct: 306 EDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVK-AMQEALAKLKEEEERQKR 360
Score = 49.7 bits (117), Expect = 4e-06
Identities = 72/345 (20%), Positives = 140/345 (40%), Gaps = 65/345 (18%)
Query: 17 PASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKK------VERLTMQV 70
PASE++ E P + E+++E D+++++++K+K E ++EKKK V+ + +
Sbjct: 293 PASEEKAETP----TAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL 348
Query: 71 SSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQF 130
+ L+ E + QK E ERI K+ +EL + +K +
Sbjct: 349 AKLKEEE------ERQKREEEERI------KRLEELE--------------AKRKEEERL 382
Query: 131 SGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSG 190
E+ + K+++E LKK + KS E + +E ++L PS
Sbjct: 383 EQEKRERKKQKEKERKERLKKEGKLLTKSQRE------ARARAEATLKLLQAQGVEVPSK 436
Query: 191 KPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE 250
LPK + + KR K P+ L + S+ E E + E
Sbjct: 437 DSLPKKRP--------------IYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPE 482
Query: 251 SEEEPPKKTAKREKPKQKA---------TSKSKKSVKSANVKKADSSTTKKNQNSSKKES 301
EE PP + E+ + A + + + V+ V ++ + ++E
Sbjct: 483 KEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEE 542
Query: 302 ESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQI 346
E E+S ++E + + DEE ++ + + L++ K++
Sbjct: 543 EDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEM 587
Score = 44.3 bits (103), Expect = 2e-04
Identities = 82/370 (22%), Positives = 132/370 (35%), Gaps = 60/370 (16%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEE------DEDDEEEEEEEKEKSLIV 54
+ A A+ E +P E E ++ + ++ D++D EE E++ KS
Sbjct: 67 LEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSK-- 124
Query: 55 EGKREKKKVERLTMQVSSLQREPFTI----AQGKGQKLCEI---------------ERIH 95
K K KVE M S + F A+GK QK + ER
Sbjct: 125 --KTAKPKVE---MYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSR 179
Query: 96 FFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNA 155
S + DE + L +R G + K G E +K K KK
Sbjct: 180 INSSGESGDES---DEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKK---- 232
Query: 156 MLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMAR 215
E + ER + E K + + L KK SK + +R
Sbjct: 233 -----AEKKERERKKRDEEKAK------LRKLKEKEELETGKKDQSKQKESQRKFEEETV 281
Query: 216 KAKRTKCPEIL--SDESSS--------DEDEKKNKEESSDDEDKESEEEPPKKTAKREKP 265
K+K T ++ S+E + +E +KK K++ +KE +E+ KK +
Sbjct: 282 KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATV 341
Query: 266 KQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEEL 325
K + +K + K+ + K+ + K E E ++ KK K+ E L
Sbjct: 342 KAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERL 401
Query: 326 KETIKKLLAS 335
K+ K L S
Sbjct: 402 KKEGKLLTKS 411
Score = 44.3 bits (103), Expect = 2e-04
Identities = 83/377 (22%), Positives = 141/377 (37%), Gaps = 70/377 (18%)
Query: 27 GPREESEEEED--EDDEEEEEEEKEKSLI----VEGKREKKKVERLTMQVSSLQREPF-- 78
G ++S ++ D E+DE+ ++ KE+S I G + ++ Q + + +P
Sbjct: 152 GKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPN 211
Query: 79 ---------------TIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSL 123
T+AQ K +K E ER KK+ +E L KL
Sbjct: 212 IESGNEDDDASFKIKTVAQKKAEKK-ERER------KKRDEEKAKLRKLKEKEE------ 258
Query: 124 KKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFL 183
E G K++E +KF +KS V + + + K
Sbjct: 259 -----------LETGKKDQSKQKESQRKFEEETVKSKVTV---DTGVIPASEEKAETPTA 304
Query: 184 MHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEES 243
G K KK KG K+E+ +K T + + E+E++ K E
Sbjct: 305 AEDDNEGDKKKKDKKK-KKGEKEEKEKEKKKGPSKAT-VKAMQEALAKLKEEEERQKREE 362
Query: 244 SD-------------DEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTT 290
+ +E++ +E+ +K K ++ K++ + K KS +A + T
Sbjct: 363 EERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEAT 422
Query: 291 KKNQNSSKKESESEDSSDDEPLI---KKLKKPPTDEELKETIKKLLASANLEEVTMKQIC 347
K + E S+DS + I KK KK P E KE + + A +E M+Q
Sbjct: 423 LKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVE--VMEQGV 480
Query: 348 KKVYENYPTYDLTERKD 364
+ E P + E +D
Sbjct: 481 PEKEETPPPVEPEEEED 497
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 1 MSASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 60
M++ + EG ++ PE EE EEEE++++ EEEEEE+ +S EG E
Sbjct: 509 MASDEETEKVEGNKVHIEVKENPEEE--EEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
Query: 61 KKVERLTMQVSSLQREP 77
+KV +L ++P
Sbjct: 567 EKVSDEKDSGKTLDKKP 583
Score = 28.9 bits (63), Expect = 7.9
Identities = 31/129 (24%), Positives = 47/129 (36%), Gaps = 42/129 (32%)
Query: 236 EKKNKEESSDDEDKE--------------SEEEPPKKTAKREKPKQKATSKSKKSVK--- 278
++KNK E S +D + E+EP K K++K K+K +K
Sbjct: 4 KQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELE 63
Query: 279 ----SANVKKADSSTT------------------KKNQNSSKK---ESESEDSSDDEPLI 313
A KAD T KK Q K+ +++SE+ D +
Sbjct: 64 ELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKS 123
Query: 314 KKLKKPPTD 322
KK KP +
Sbjct: 124 KKTAKPKVE 132
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 54.7 bits (130), Expect = 1e-07
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 1/111 (0%)
Query: 236 EKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSK-SKKSVKSANVKKADSSTTKKNQ 294
+KK KE +E +E+EEE K+ ++EK K+K K KK K +K KK +
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 295 NSSKKESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQ 345
KK+ E E+ ++E ++ K+ EE + KK EE K+
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 53.9 bits (128), Expect = 2e-07
Identities = 28/113 (24%), Positives = 55/113 (48%)
Query: 215 RKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSK 274
+K K+ K E + ++E+E+K + ++K E+E KKT + EK K+K + K
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 275 KSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKE 327
+ K K+ + ++ + +KE E ++ KK ++ +EE K+
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114
Score = 50.1 bits (118), Expect = 3e-06
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 9/98 (9%)
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246
K K K KKT +KE+ RK KR K +E+E++ +EE ++
Sbjct: 34 KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKK---------KKEEEEREEEEEEEEE 84
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKK 284
E +E E+E ++ K++K ++K + KK + KK
Sbjct: 85 EKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 46.6 bits (109), Expect = 4e-05
Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 6/97 (6%)
Query: 202 KGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEK------KNKEESSDDEDKESEEEP 255
+G +KE+ K K+ K E + +E++K K KEE +E++E EEE
Sbjct: 26 EGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEE 85
Query: 256 PKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKK 292
++ K E ++K K ++ + KK TKK
Sbjct: 86 KEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 46.2 bits (108), Expect = 5e-05
Identities = 26/55 (47%), Positives = 35/55 (63%), Gaps = 4/55 (7%)
Query: 15 TQPASEKEPEMPGPR----EESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVER 65
T+ EKE E + ++ EEEE E++EEEEEEEKE+ EG+R KKK +R
Sbjct: 49 TEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR 103
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/124 (21%), Positives = 54/124 (43%), Gaps = 3/124 (2%)
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEE 254
K KK + + E + K K E ++ E +KK KE ++ KE EEE
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET---EKRKEKEEE 58
Query: 255 PPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIK 314
K+ KR+K K++ + ++ + ++ + ++ + K+ + E+ + +
Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Query: 315 KLKK 318
K KK
Sbjct: 119 KTKK 122
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 6/88 (6%)
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246
K K K K K +KE RK K+ K E +E +E+EK+ +E+
Sbjct: 36 KRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGR 95
Query: 247 EDKE------SEEEPPKKTAKREKPKQK 268
K+ EEE KK +R K K+K
Sbjct: 96 RRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 38.1 bits (87), Expect = 0.013
Identities = 25/121 (20%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 215 RKAKRTKCPEILSDESSSDEDEK------KNKEESSDDEDKESEEEPPKKTAKRE----- 263
+K K+ + E E + +E+EK K KE+ + E K+ +E K+ K E
Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62
Query: 264 KPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE 323
K K+K + ++ + ++ + +K + +K+ + ++E KK ++ T +
Sbjct: 63 KRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Query: 324 E 324
+
Sbjct: 123 K 123
Score = 36.6 bits (83), Expect = 0.038
Identities = 22/51 (43%), Positives = 30/51 (58%), Gaps = 5/51 (9%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEE-----EKEKSLIVEGKREKKKVER 65
+K+ E EE EEEE+E +EEE+EE +K+K E + EKKK R
Sbjct: 67 KKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117
Score = 33.5 bits (75), Expect = 0.32
Identities = 22/74 (29%), Positives = 37/74 (50%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFT 79
+K+ + E E EE E++EE+E + KEK ++EKKK + T + + E
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 80 IAQGKGQKLCEIER 93
+ + +K E ER
Sbjct: 62 RKRKRKKKKEEEER 75
Score = 31.2 bits (69), Expect = 1.6
Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 13/55 (23%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEE-------------EEEKEKSLIVEGKREKK 61
+KE E EE EEEE E++E+EE EEE+EK K +KK
Sbjct: 69 KKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 29.6 bits (65), Expect = 4.6
Identities = 14/55 (25%), Positives = 32/55 (58%)
Query: 11 EGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVER 65
E T+ EKE + R+E +E+++ + +E E++++ E KR++K+ ++
Sbjct: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK 69
Score = 28.9 bits (63), Expect = 7.9
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 20 EKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLT 67
E+ E EE +EEE++++ +++K++ E + +KKK R T
Sbjct: 73 EEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 54.7 bits (130), Expect = 1e-07
Identities = 37/141 (26%), Positives = 69/141 (48%), Gaps = 7/141 (4%)
Query: 187 KPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDD 246
+P KP PK + K K R S + + + S ESSS++DE+ ++E+ D+
Sbjct: 936 RPGTKP-PKRDEERGKTQGKHRKSFALDSEGEEA------SQESSSEKDEEDDEEDEEDE 988
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
+ +E+ + K+T + +++ S SK S+ + + + DS++ ++ +SS S S S
Sbjct: 989 DREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSS 1048
Query: 307 SDDEPLIKKLKKPPTDEELKE 327
S + DEE +E
Sbjct: 1049 SSSSSSSSSSESSSEDEEEEE 1069
Score = 42.0 bits (97), Expect = 9e-04
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 14/101 (13%)
Query: 216 KAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEE------PPKKTAKREKPKQKA 269
K KR + EI E+S ++ + + D++D E E+E P K KR++ + K
Sbjct: 894 KVKRKEPSEI--SEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKT 951
Query: 270 TSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDE 310
K +KS DS + +Q SS ++ E +D D+E
Sbjct: 952 QGKHRKSF------ALDSEGEEASQESSSEKDEEDDEEDEE 986
Score = 37.0 bits (84), Expect = 0.029
Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 29/89 (32%)
Query: 4 SAPAAEGEGTPTQPASEKEPEMPGPR-----------------------------EESEE 34
S PA E E P Q EP PG + +ES
Sbjct: 915 STPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSS 974
Query: 35 EEDEDDEEEEEEEKEKSLIVEGKREKKKV 63
E+DE+D+EE+EE++++ V+ +++ +V
Sbjct: 975 EKDEEDDEEDEEDEDREEAVDTTKKETEV 1003
Score = 37.0 bits (84), Expect = 0.029
Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 4 SAPAAEGEGTPTQPASEKEPEMPGP----REESEEEEDEDDEEEEEEEKEKSLIVEGK 57
S+PA E P +E E P REE EEE +E+ EEEEEE + S +G+
Sbjct: 1329 SSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGE 1386
Score = 35.8 bits (81), Expect = 0.064
Identities = 18/53 (33%), Positives = 33/53 (62%), Gaps = 5/53 (9%)
Query: 8 AEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREK 60
+EGE + +SEK+ E ++ E+EEDED EE + K+++ + +G+ E+
Sbjct: 963 SEGEEASQESSSEKDEE-----DDEEDEEDEDREEAVDTTKKETEVSDGEDEE 1010
Score = 30.0 bits (66), Expect = 3.5
Identities = 13/49 (26%), Positives = 28/49 (57%)
Query: 14 PTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKK 62
P++ + E + P P +EE+ED+ ++E+E E + KR++++
Sbjct: 900 PSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKPPKRDEER 948
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 11/145 (7%)
Query: 186 PKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSD 245
P S KP P S K+ S R ++R + E+ + E KN E SD
Sbjct: 107 PYGSDKPWP------SLLDKEREESLRQKRLSERERIGELGAPEVWGLSP--KNPEPDSD 158
Query: 246 DEDKESEEEPPKKTAKR---EKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESE 302
+ +EEP K T E+ K+K +S+SK+ K KK+ KK S +S+
Sbjct: 159 EHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSD 218
Query: 303 SEDSSDDEPLIKKLKKPPTDEELKE 327
SE S DE ++ KK E+ K+
Sbjct: 219 SETDSSDEDNKRRAKKAKKKEKKKK 243
Score = 52.8 bits (125), Expect = 5e-07
Identities = 39/116 (33%), Positives = 54/116 (46%), Gaps = 16/116 (13%)
Query: 194 PKSKKTCSKGS---KKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKE 250
PK T + S KK+++S R KR K + SS KK E+S D D E
Sbjct: 168 PKKSTTSASTSEEEKKKKSSRSKERSKKRRK-------KKSSKRKHKKYSEDSDSDSDSE 220
Query: 251 --SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESE 304
S +E K+ AK+ K K+K K K KK + K++ +SS KES+ E
Sbjct: 221 TDSSDEDNKRRAKKAKKKEKKKKHRSKKYK----KKRSKKSRKESSDSSSKESQEE 272
Score = 45.8 bits (107), Expect = 6e-05
Identities = 37/143 (25%), Positives = 60/143 (41%), Gaps = 19/143 (13%)
Query: 186 PKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSD 245
PK S S++ K S + + S RK K +K + S D D + E S
Sbjct: 168 PKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKH---KKYSEDSDSDSDSETDSS 224
Query: 246 DED-----KESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKE 300
DED K+++++ KK + +K K+K + KS+K ++ K++ + K
Sbjct: 225 DEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKA 284
Query: 301 SESED-----------SSDDEPL 312
E D S DD+PL
Sbjct: 285 EEPSDLIGPEAPKTLTSQDDKPL 307
>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
Length = 872
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/171 (23%), Positives = 82/171 (47%), Gaps = 15/171 (8%)
Query: 154 NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGM 213
+A++K + + G ++L RIL + +GKP SKK ++ R +G+
Sbjct: 244 DAIVKMLDAAVIKMEGGTENDL--RILEQEEEEEQAGKPGEPSKK------EEGRAGAGL 295
Query: 214 ARKAKRTKCPEILSDESSSDEDEKKNKEESS-DDEDKESEEEPPKKTAKREKPKQKATSK 272
++T +D+ ED K+ + +SS DD+ K+SE + K+ K + K+ S
Sbjct: 296 GDGERKT------NDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSS 349
Query: 273 SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE 323
K++ K + D + ++++ S+ E+ + E +K+ +KP +E
Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEE 400
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 195 KSKKTCSKGSKKER--NSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESE 252
K+KK+ G K+E+ +S A+K+ + + + D+S + +++ ES + +E +
Sbjct: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
Query: 253 EEPPKKTAKREKPKQKATSKSK 274
EE + ++EKPK++ K K
Sbjct: 384 EEAEEALKEKEKPKEEEWEKPK 405
Score = 30.0 bits (66), Expect = 3.5
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEE- 253
++KK+ K ++K + E ES E+EK+ EE+ +++K EE
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESE---SESGQAEEEKEEAEEALKEKEKPKEEE 400
Query: 254 -EPPKKTAKRE---KPKQKATSKSKKSVKSANVKKAD 286
E PK A E +P K S +++ + N+ +A+
Sbjct: 401 WEKPKDAAGLECKPRPLHKTCSLFMRNI-APNISRAE 436
>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
Length = 876
Score = 54.3 bits (129), Expect = 2e-07
Identities = 41/171 (23%), Positives = 82/171 (47%), Gaps = 15/171 (8%)
Query: 154 NAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGM 213
+A++K + + G ++L RIL + +GKP SKK ++ R +G+
Sbjct: 244 DAIVKMLDAAVIKMEGGTENDL--RILEQEEEEEQAGKPGEPSKK------EEGRAGAGL 295
Query: 214 ARKAKRTKCPEILSDESSSDEDEKKNKEESS-DDEDKESEEEPPKKTAKREKPKQKATSK 272
++T +D+ ED K+ + +SS DD+ K+SE + K+ K + K+ S
Sbjct: 296 GDGERKT------NDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSS 349
Query: 273 SKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE 323
K++ K + D + ++++ S+ E+ + E +K+ +KP +E
Sbjct: 350 KKRNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEEALKEKEKPKEEE 400
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/82 (26%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 195 KSKKTCSKGSKKER--NSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESE 252
K+KK+ G K+E+ +S A+K+ + + + D+S + +++ ES + +E +
Sbjct: 324 KTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEEK 383
Query: 253 EEPPKKTAKREKPKQKATSKSK 274
EE + ++EKPK++ K K
Sbjct: 384 EEAEEALKEKEKPKEEEWEKPK 405
Score = 30.0 bits (66), Expect = 3.5
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 195 KSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEE- 253
++KK+ K ++K + E ES E+EK+ EE+ +++K EE
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESESE---SESGQAEEEKEEAEEALKEKEKPKEEE 400
Query: 254 -EPPKKTAKRE---KPKQKATSKSKKSVKSANVKKAD 286
E PK A E +P K S +++ + N+ +A+
Sbjct: 401 WEKPKDAAGLECKPRPLHKTCSLFMRNI-APNISRAE 436
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/163 (23%), Positives = 77/163 (47%), Gaps = 15/163 (9%)
Query: 194 PKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDESSS----DEDEKKNKEESSDDEDK 249
P S + S+ R S +R +R+K P S K +++ +D++K
Sbjct: 261 PSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEK 320
Query: 250 ESEEEPPK--------KTAKREKPKQKATS--KSKKSVKSANVKKADSSTTKKNQNSSKK 299
+ + PPK ++A RE+ ++++ S +S K +S K + S + ++++ KK
Sbjct: 321 KRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKK 380
Query: 300 ESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVT 342
+ + E S D+ KK D+E K+ +K + ++++VT
Sbjct: 381 DKDKERSRDERERSTSKKKKSKDKE-KDRERKSESDKDVKQVT 422
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/148 (22%), Positives = 67/148 (45%), Gaps = 3/148 (2%)
Query: 187 KPSGKPLPKSKKTC--SKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESS 244
K K PKS T S+ + +ER + K P + S +++K+E
Sbjct: 320 KKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK 379
Query: 245 DDEDKE-SEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESES 303
D+DKE S +E + T+K++K K K + +KS +VK+ ++ Q ++ +
Sbjct: 380 KDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKK 439
Query: 304 EDSSDDEPLIKKLKKPPTDEELKETIKK 331
E+ E K K+ ++ +++++
Sbjct: 440 EEKKPIETGSPKTKECSVEKGTGDSLRE 467
Score = 35.8 bits (81), Expect = 0.064
Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 19/148 (12%)
Query: 168 RSGVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARK-AKRTKCPEIL 226
RSG S R + PS + K KK K KER+ R +K+ K +
Sbjct: 349 RSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK---KDKDKERSRDERERSTSKKKKSKDKE 405
Query: 227 SD---ESSSDEDEKKNKEESSDDE---DKESEEEPPKKTAKREKPKQKATSKSKKSVKSA 280
D +S SD+D K+ + ++E D E E++ KK + PK K S K + S
Sbjct: 406 KDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSL 465
Query: 281 NVKKADSSTTKKNQNSSKKESESEDSSD 308
K N E D SD
Sbjct: 466 RESKV---------NGDDHHEEDMDMSD 484
Score = 34.7 bits (78), Expect = 0.14
Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 10 GEGTPTQPASEKEP--EMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVER 65
G +P +P S K P PR +E++ + D+E +E+E+S + K + K+ +R
Sbjct: 351 GTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDR 408
Score = 33.5 bits (75), Expect = 0.32
Identities = 24/123 (19%), Positives = 56/123 (45%), Gaps = 5/123 (4%)
Query: 201 SKGSKKERNSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTA 260
S K + +S + KR + + L ++ + D+K+ K S + P +
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLIS-AAIEPDKKEEKRRHSRSRSRSRRRRTPSSSR 265
Query: 261 ---KREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLK 317
R + ++++ SKS+ +S + ++ S + ++ + S+ S++ D ++ K+ K
Sbjct: 266 HRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRR-SRSTSKTRDKKKEDKEKKRSK 324
Query: 318 KPP 320
PP
Sbjct: 325 TPP 327
>gi|224591430 Ly1 antibody reactive homolog [Homo sapiens]
Length = 379
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/266 (24%), Positives = 108/266 (40%), Gaps = 29/266 (10%)
Query: 113 LYNRPGT---VSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 169
L RP V L + + F P +K Q K LK ++L + + +
Sbjct: 84 LIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNS-LKVHNESILDQVWNIFSEASN 142
Query: 170 G--VNSELVKRILNFLMHPKPS-GKPLPKSKKTCS-------KGSKKERNSSGMARKAKR 219
VN E +R L+ + +P +P SK + K +K+ER +K KR
Sbjct: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ-KKRKR 201
Query: 220 TKCPEILSDESSSDEDEKKNKEESSDDEDKES--EEEPPKKTAKREKPKQKATSKSKKSV 277
K L + + ++K K + + D E+ EE P + ++ K+K K S
Sbjct: 202 EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
Query: 278 KSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE-------ELKETIK 330
+ A V K+ + S+ E++S+ P + +P DE K TIK
Sbjct: 262 EEARV-----GAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIK 316
Query: 331 KLLASANLEEVTMKQICKKVYENYPT 356
+L A E+T+K++ KKV Y T
Sbjct: 317 AILKQAPDNEITIKKLRKKVLAQYYT 342
>gi|8923398 Ly1 antibody reactive homolog [Homo sapiens]
Length = 379
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/266 (24%), Positives = 108/266 (40%), Gaps = 29/266 (10%)
Query: 113 LYNRPGT---VSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 169
L RP V L + + F P +K Q K LK ++L + + +
Sbjct: 84 LIKRPNVSPKVRELLEQISAFDNVPRKKAKFQNWMKNS-LKVHNESILDQVWNIFSEASN 142
Query: 170 G--VNSELVKRILNFLMHPKPS-GKPLPKSKKTCS-------KGSKKERNSSGMARKAKR 219
VN E +R L+ + +P +P SK + K +K+ER +K KR
Sbjct: 143 SEPVNKEQDQRPLHPVANPHAEISTKVPASKVKDAVEQQGEVKKNKRERKEERQ-KKRKR 201
Query: 220 TKCPEILSDESSSDEDEKKNKEESSDDEDKES--EEEPPKKTAKREKPKQKATSKSKKSV 277
K L + + ++K K + + D E+ EE P + ++ K+K K S
Sbjct: 202 EKKELKLENHQENSRNQKPKKRKKGQEADLEAGGEEVPEANGSAGKRSKKKKQRKDSASE 261
Query: 278 KSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDE-------ELKETIK 330
+ A V K+ + S+ E++S+ P + +P DE K TIK
Sbjct: 262 EEARV-----GAGKRKRRHSEVETDSKKKKMKLPEHPEGGEPEDDEAPAKGKFNWKGTIK 316
Query: 331 KLLASANLEEVTMKQICKKVYENYPT 356
+L A E+T+K++ KKV Y T
Sbjct: 317 AILKQAPDNEITIKKLRKKVLAQYYT 342
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 202 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 249
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
Query: 250 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 303
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
Query: 304 EDSSDDEPLIKKLKKPPTDEELKETIKK 331
E+ + LKK PT +E K+ +K
Sbjct: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
Score = 48.5 bits (114), Expect = 1e-05
Identities = 73/345 (21%), Positives = 124/345 (35%), Gaps = 66/345 (19%)
Query: 2 SASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEE-KEKSLIVEGKREK 60
S S + GE T+P + P E EE+ +++ +E + ++ R
Sbjct: 11 SESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNA 70
Query: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
K+ +T + E A GK + + + E + F + D L++L ++ G
Sbjct: 71 MKIRDVTKCLEEF--ELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKK 128
Query: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
K N S + ++K+ N + I
Sbjct: 129 KMNKNNAKALSTL------------RQKIRKY-------------------NRDFESHIT 157
Query: 181 NFLMHPKPSGKPLPKSKKTCSKGS-----------------KKERNSSGMARKAKRTKCP 223
++ +P+ S + + S+GS KK SG +RK + K
Sbjct: 158 SYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMD 216
Query: 224 EILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK 283
+ D S++DE + +S D D E EE A R K T + KK+ + K
Sbjct: 217 DEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAE----K 272
Query: 284 KADSSTTKKNQNSSKK--ESESEDSSDDE--------PLIKKLKK 318
K + KK+ SK+ E E ED+ E PL+K+ K
Sbjct: 273 KREDKAKKKHDRKSKRLDEEEEEDNEGGEWERVRGGVPLVKEKPK 317
Score = 32.0 bits (71), Expect = 0.93
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 307 SDDE---------PLIKKLKKPPTDEELK 326
SD++ +KK + P+ E K
Sbjct: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
>gi|83700233 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 202 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 249
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
Query: 250 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 303
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
Query: 304 EDSSDDEPLIKKLKKPPTDEELKETIKK 331
E+ + LKK PT +E K+ +K
Sbjct: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
Score = 48.9 bits (115), Expect = 7e-06
Identities = 71/343 (20%), Positives = 124/343 (36%), Gaps = 63/343 (18%)
Query: 2 SASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEE-KEKSLIVEGKREK 60
S S + GE T+P + P E EE+ +++ +E + ++ R
Sbjct: 11 SESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNA 70
Query: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
K+ +T + E A GK + + + E + F + D L++L ++ G
Sbjct: 71 MKIRDVTKCLEEF--ELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKK 128
Query: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
K N S + ++K+ N + I
Sbjct: 129 KMNKNNAKALSTL------------RQKIRKY-------------------NRDFESHIT 157
Query: 181 NFLMHPKPSGKPLPKSKKTCSKGS-----------------KKERNSSGMARKAKRTKCP 223
++ +P+ S + + S+GS KK SG +RK + K
Sbjct: 158 SYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMD 216
Query: 224 EILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK 283
+ D S++DE + +S D D E EE A R K T + K K+A K
Sbjct: 217 DEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDK---KAAEKK 273
Query: 284 KADSSTTKKNQNSSKKESESEDSSDDE--------PLIKKLKK 318
+ D + K ++ S + + E ED+ E PL+K+ K
Sbjct: 274 REDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPK 316
Score = 32.0 bits (71), Expect = 0.93
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 307 SDDE---------PLIKKLKKPPTDEELK 326
SD++ +KK + P+ E K
Sbjct: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
>gi|4503525 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 53.5 bits (127), Expect = 3e-07
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 18/148 (12%)
Query: 202 KGSKKERNSSGMARKAKRTKCPEILSD------------ESSSDEDEKKNKEESSDDEDK 249
+G KK ++ A R K + D E S+DED +KN+E+S D+
Sbjct: 125 EGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGSSDE 184
Query: 250 ESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQN------SSKKESES 303
+ +E+ +K + + +S+K +K + + DS ++ +++ SS +SE
Sbjct: 185 DEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEE 244
Query: 304 EDSSDDEPLIKKLKKPPTDEELKETIKK 331
E+ + LKK PT +E K+ +K
Sbjct: 245 EEGKQTALASRFLKKAPTTDEDKKAAEK 272
Score = 48.9 bits (115), Expect = 7e-06
Identities = 71/343 (20%), Positives = 124/343 (36%), Gaps = 63/343 (18%)
Query: 2 SASAPAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEE-KEKSLIVEGKREK 60
S S + GE T+P + P E EE+ +++ +E + ++ R
Sbjct: 11 SESESSLSGEELVTKPVGGNYGKQPLLLSEDEEDTKRVVRSAKDKRFEELTNLIRTIRNA 70
Query: 61 KKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTV 120
K+ +T + E A GK + + + E + F + D L++L ++ G
Sbjct: 71 MKIRDVTKCLEEF--ELLGKAYGKAKSIVDKEGVPRFYIRILADLEDYLNELWEDKEGKK 128
Query: 121 SSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRIL 180
K N S + ++K+ N + I
Sbjct: 129 KMNKNNAKALSTL------------RQKIRKY-------------------NRDFESHIT 157
Query: 181 NFLMHPKPSGKPLPKSKKTCSKGS-----------------KKERNSSGMARKAKRTKCP 223
++ +P+ S + + S+GS KK SG +RK + K
Sbjct: 158 SYKQNPEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLK-KMD 216
Query: 224 EILSDESSSDEDEKKNKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVK 283
+ D S++DE + +S D D E EE A R K T + K K+A K
Sbjct: 217 DEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDK---KAAEKK 273
Query: 284 KADSSTTKKNQNSSKKESESEDSSDDE--------PLIKKLKK 318
+ D + K ++ S + + E ED+ E PL+K+ K
Sbjct: 274 REDKAKKKHDRKSKRLDEEEEDNEGGEWERVRGGVPLVKEKPK 316
Score = 32.0 bits (71), Expect = 0.93
Identities = 21/89 (23%), Positives = 39/89 (43%), Gaps = 9/89 (10%)
Query: 247 EDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDS 306
EDKE +++ K AK ++ K + +S + ++++ K E +SE S
Sbjct: 122 EDKEGKKKMNKNNAKALSTLRQKIRKYNRDFESHITSYKQNPEQSADEDAEKNEEDSEGS 181
Query: 307 SDDE---------PLIKKLKKPPTDEELK 326
SD++ +KK + P+ E K
Sbjct: 182 SDEDEDEDGVSAATFLKKKSEAPSGESRK 210
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 52.8 bits (125), Expect = 5e-07
Identities = 66/296 (22%), Positives = 127/296 (42%), Gaps = 53/296 (17%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQR 75
Q + + E+ EESEEEE+++ EEE E+E++ + K E + + ++
Sbjct: 772 QAVTTSKWELFDQHEESEEEENQNQEEESEDEEDT--------QSSKSEEHHLYSNPIKE 823
Query: 76 EPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPF 135
E + + K K E +S++K +LR + + + S K+ P
Sbjct: 824 E---MTESKFSKYSE-------MSEEKRAKLREIELKVMKFQDELESGKR--------PK 865
Query: 136 EKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPK 195
+ G + +E ++ +R+ +L+ E +LER + K L K K
Sbjct: 866 KPG----QSFQEQVEHYRDKLLQREKEK-ELERERERDKKDKEKLESRSKDKKE-----K 915
Query: 196 SKKTCSKGSKKERNSSG----MARKAKRTKCPEILSDESSSDEDEKKNKEESSDDEDKES 251
+ T ++ +K R+S+ + +R K P S+ S + E+ +KE S + S
Sbjct: 916 DECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERS--ERSERSHKESS---RSRSS 970
Query: 252 EEEPPKKTAKREK--------PKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKK 299
++ P+ +K+ K PK+ S+S+ KS ++ S + ++ SKK
Sbjct: 971 HKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026
Score = 40.4 bits (93), Expect = 0.003
Identities = 31/95 (32%), Positives = 52/95 (54%), Gaps = 10/95 (10%)
Query: 234 EDEKKNKEE-SSDDEDKESEEE--PPKKTAKREKPKQKATSKSK--KSVKSANVKKADSS 288
E +KK+KE+ S +DK+ ++E P +K KR + S+S + VKS + K S
Sbjct: 896 ERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPK---SE 952
Query: 289 TTKKNQNSSKKESESEDSSDDEP--LIKKLKKPPT 321
+++++ S K+ S S S D P + KK K+ P+
Sbjct: 953 RSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPS 987
Score = 32.0 bits (71), Expect = 0.93
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 209 NSSGMARKAKRTKCPEILSDESSSDEDEKKNKEESSDDED-----KESEEEPPKKTAKRE 263
+ S + +A T E+ S+E+E +N+EE S+DE+ K E K E
Sbjct: 765 DESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEE 824
Query: 264 KPKQKATSKSKKS-VKSANVKKADSSTTK 291
+ K + S+ S K A +++ + K
Sbjct: 825 MTESKFSKYSEMSEEKRAKLREIELKVMK 853
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 52.4 bits (124), Expect = 7e-07
Identities = 69/338 (20%), Positives = 134/338 (39%), Gaps = 39/338 (11%)
Query: 16 QPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQR 75
+P + + E P PR E E DE++EEE+E E E R + L Q SS ++
Sbjct: 1047 EPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPR---EYFRRLSSQDVLRCQSSSKRK 1103
Query: 76 EPFTIAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPF 135
+ + + +K D + + P T + LKK G G
Sbjct: 1104 SKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLE-----PDTSTPLKKKKGWPKGK-- 1156
Query: 136 EKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKPL-- 193
+ + +KK+ F+ + E++ + E + I PK KP
Sbjct: 1157 SRKPIHWKKRPGRKPGFKLSR-----EIMPVSTQACVIEPIVSI------PKAGRKPKIQ 1205
Query: 194 -------PKSKKTCSKGSKKERNSSGMARKAKRTKCPEILSDE--SSSDEDEKKNKEESS 244
PK + K+E A +A+ + + S E ++S D + E +
Sbjct: 1206 ESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETET 1265
Query: 245 DDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESE 304
+ + E EEE P R +Q+ + + ++ ++ ++ + + + QN + +
Sbjct: 1266 KEPEVEEEEEKP-----RVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDED 1320
Query: 305 DSSDDEPLIKKLKKPPTDEELKET--IKKLLASANLEE 340
D + K+L++ PT E++KE +++ AN+++
Sbjct: 1321 DGHLESTKKKELEEQPTREDVKEEPGVQESFLDANMQK 1358
Score = 42.7 bits (99), Expect = 5e-04
Identities = 75/362 (20%), Positives = 134/362 (37%), Gaps = 26/362 (7%)
Query: 5 APAAEGEGTPTQPASEKEPEMPGPREESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVE 64
A A E E + A+ E P + S E E E E EEE+EK + E +R+ ++ +
Sbjct: 1231 AEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQ 1290
Query: 65 RLTMQVSSLQREPFT--IAQGKGQKLCEIERIHFFLSKKKTDELRNLHKLLYNRPGTVSS 122
+ + + E AQ + + H +KKK E + + + PG S
Sbjct: 1291 QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVKEEPGVQES 1350
Query: 123 -LKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLD--LERSGVNSELVKRI 179
L N+ + +K + +EE + + + + D E S EL++
Sbjct: 1351 FLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEEDSHTKEELIE-- 1408
Query: 180 LNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRTKCP-EILSDESSSDEDEKK 238
L S L + S ++ G + + T + L + +DED +
Sbjct: 1409 LKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAACQTLQSYTQADEDPQM 1468
Query: 239 NKEESSDDEDKESEEEPPKKTAKREKPKQKATSKSKKSVKSANVKKADSSTTKKNQNSSK 298
+ E + SE P + Q S+S +SV S NV +S T+ +
Sbjct: 1469 SMVE----DCHASEHNSPISSV------QSHPSQSVRSVSSPNVPALESGYTQISPEQGS 1518
Query: 299 KESESEDSSDDEPLIKKLKKPPTDEELKETIKKLLASANLEEVTMKQICKKVYENYPTYD 358
+ S + + P+ + P + ++ + + E T + YEN +YD
Sbjct: 1519 LSAPSMQNMETSPM---MDVPSVSDHSQQVVDSGFSDLGSIESTTEN-----YENPSSYD 1570
Query: 359 LT 360
T
Sbjct: 1571 ST 1572
Score = 35.8 bits (81), Expect = 0.064
Identities = 76/315 (24%), Positives = 125/315 (39%), Gaps = 47/315 (14%)
Query: 30 EESEEEEDEDDEEEEEEEKEKSLIVEGKREKKKVERLTMQVSSLQREPFTIAQGKGQKLC 89
EE EE E+ ++EE + +E+E + V + E+ + V S +++P +A +L
Sbjct: 789 EEEEEAEEGENEEPQCQERELEISVGKSVSHENKEQDSYSVES-EKKPEVMAPVSSTRLS 847
Query: 90 EIERIHFFLSKKKTDELR----NLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKK 145
+ H L R ++ R G S K + + S P E+ +K
Sbjct: 848 KQVLPHDSLPANSQPSRRGRWGRKNRKTQERFGDKDS-KLLLEETSSAPQEQYGECGEKS 906
Query: 146 EEMLKKFRNAMLKSICEVLDLERSGVNSELVKRILNFLMHPKPSGKP-LPKSKKTCSKGS 204
E +++ + E V SE P GKP LP K+ S+G
Sbjct: 907 EATQEQYTES-----------EEQLVASE---------EQPSQDGKPDLP--KRRLSEGV 944
Query: 205 KKER---NSSGMARKAKRTKCPEILSDE-SSSDEDEKKNKEESSDDEDKES---EEEPP- 256
+ R S A K + T+ E L S D + ESS++E++ PP
Sbjct: 945 EPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSEEEEEPESPRSSSPPI 1004
Query: 257 --KKTAKREKP--KQKATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPL 312
K T KR+KP ++ + +K S+ V + S TT+ + EDS + P+
Sbjct: 1005 LTKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTE------VLDEPFEDSDSERPM 1058
Query: 313 IKKLKKPPTDEELKE 327
+ DEE +E
Sbjct: 1059 PRLEPTFEIDEEEEE 1073
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.121 0.317
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,199,865
Number of Sequences: 37866
Number of extensions: 897373
Number of successful extensions: 46704
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1168
Number of HSP's successfully gapped in prelim test: 1075
Number of HSP's that attempted gapping in prelim test: 11414
Number of HSP's gapped (non-prelim): 19444
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.