Guide to the Human Genome
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Search of human proteins with 4503031

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503031 CASP2 and RIPK1 domain containing adaptor with death
domain [Homo sapiens]
         (199 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503031 CASP2 and RIPK1 domain containing adaptor with death ...   397   e-111
gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]           47   1e-05
gi|39995061 caspase 2 isoform 3 [Homo sapiens]                         44   7e-05
gi|154448890 THO complex 1 [Homo sapiens]                              37   0.011
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        36   0.025
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         36   0.025
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         36   0.025
gi|4502379 B-cell CLL/lymphoma 10 [Homo sapiens]                       35   0.032
gi|4505229 Fas-associated via death domain [Homo sapiens]              34   0.072
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa...    33   0.12 
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap...    33   0.12 
gi|61742786 leucine rich repeat and death domain containing prot...    31   0.61 
gi|61742784 leucine rich repeat and death domain containing prot...    31   0.61 
gi|61742782 leucine rich repeat and death domain containing prot...    31   0.61 
gi|224494026 tumor necrosis factor receptor superfamily, member ...    29   3.0  
gi|224494019 tumor necrosis factor receptor superfamily, member ...    29   3.0  
gi|7662404 caspase recruitment domain family, member 8 [Homo sap...    29   3.0  
gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]    29   3.0  
gi|148596998 coiled-coil domain containing 122 [Homo sapiens]          29   3.0  
gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo...    28   3.9  
gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo...    28   3.9  
gi|169202863 PREDICTED: hypothetical protein [Homo sapiens]            28   5.1  
gi|239744373 PREDICTED: hypothetical protein XP_002343130 [Homo ...    28   5.1  
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi...    28   5.1  
gi|55749600 spire homolog 2 [Homo sapiens]                             28   5.1  
gi|226246554 hypothetical protein LOC643677 [Homo sapiens]             28   6.7  
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap...    28   6.7  
gi|51093861 caspase recruitment domain protein 10 [Homo sapiens]       27   8.8  

>gi|4503031 CASP2 and RIPK1 domain containing adaptor with death
           domain [Homo sapiens]
          Length = 199

 Score =  397 bits (1019), Expect = e-111
 Identities = 199/199 (100%), Positives = 199/199 (100%)

Query: 1   MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDI 60
           MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDI
Sbjct: 1   MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDI 60

Query: 61  LPSRGPKAFDTFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQI 120
           LPSRGPKAFDTFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQI
Sbjct: 61  LPSRGPKAFDTFLDSLQEFPWVREKLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQI 120

Query: 121 NQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSL 180
           NQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSL
Sbjct: 121 NQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSL 180

Query: 181 HNGLRAVEVDPSLLLHMLE 199
           HNGLRAVEVDPSLLLHMLE
Sbjct: 181 HNGLRAVEVDPSLLLHMLE 199


>gi|39995059 caspase 2 isoform 1 preproprotein [Homo sapiens]
          Length = 452

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 25/78 (32%), Positives = 47/78 (60%), Gaps = 1/78 (1%)

Query: 1   MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDI 60
           M    ++ L+  R+ L  ++L+  L L++L ++ I+T    + I A+     + + LL++
Sbjct: 32  MHPHHQETLKKNRVVLAKQLLLSEL-LEHLLEKDIITLEMRELIQAKVGSFSQNVELLNL 90

Query: 61  LPSRGPKAFDTFLDSLQE 78
           LP RGP+AFD F ++L+E
Sbjct: 91  LPKRGPQAFDAFCEALRE 108


>gi|39995061 caspase 2 isoform 3 [Homo sapiens]
          Length = 108

 Score = 44.3 bits (103), Expect = 7e-05
 Identities = 24/76 (31%), Positives = 45/76 (59%), Gaps = 1/76 (1%)

Query: 1   MEARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDI 60
           M    ++ L+  R+ L  ++L+  L L++L ++ I+T    + I A+     + + LL++
Sbjct: 32  MHPHHQETLKKNRVVLAKQLLLSEL-LEHLLEKDIITLEMRELIQAKVGSFSQNVELLNL 90

Query: 61  LPSRGPKAFDTFLDSL 76
           LP RGP+AFD F ++L
Sbjct: 91  LPKRGPQAFDAFCEAL 106


>gi|154448890 THO complex 1 [Homo sapiens]
          Length = 657

 Score = 37.0 bits (84), Expect = 0.011
 Identities = 33/160 (20%), Positives = 70/160 (43%), Gaps = 12/160 (7%)

Query: 36  LTENHIQEINAQTTGLRKTMLLLDILP------SRGPKAFDTFLDSL-----QEFPWVRE 84
           + EN  + +N    G R   LL    P      ++  K+   +L+++     +E P   E
Sbjct: 479 MVENEYKAVNNSNYGWRALRLLARRSPHFFQPTNQQFKSLPEYLENMVIKLAKELPPPSE 538

Query: 85  KLKKAREEAMTDLPAGDRLTGIPSHILNSSPSDRQINQLAQRLGPEWEPMVLSLGLSQTD 144
           ++K   +E   D  A  +    P    +   +  QI   A +LG +W+ +   L +  ++
Sbjct: 539 EIKTGEDEDEEDNDALLKENESPDVRRDKPVTGEQIEVFANKLGEQWKILAPYLEMKDSE 598

Query: 145 IYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSLHNGL 184
           I + + +   +++ +  +  + W+ + G  AT ++L N L
Sbjct: 599 IRQIECD-SEDMKMRAKQLLVAWQDQEGVHATPENLINAL 637


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 35.8 bits (81), Expect = 0.025
 Identities = 19/83 (22%), Positives = 42/83 (50%), Gaps = 2/83 (2%)

Query: 117  DRQINQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQAT 176
            + ++  +A  LG  W  +   L  ++  I++ +  +P+++Q Q       W +R GK AT
Sbjct: 1476 EERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHAT 1535

Query: 177  FQSLHNGLRAVEVDPSLLLHMLE 199
              +L   L   +++   ++H++E
Sbjct: 1536 DTNLVECL--TKINRMDIVHLME 1556


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 35.8 bits (81), Expect = 0.025
 Identities = 19/83 (22%), Positives = 42/83 (50%), Gaps = 2/83 (2%)

Query: 117  DRQINQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQAT 176
            + ++  +A  LG  W  +   L  ++  I++ +  +P+++Q Q       W +R GK AT
Sbjct: 1485 EERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHAT 1544

Query: 177  FQSLHNGLRAVEVDPSLLLHMLE 199
              +L   L   +++   ++H++E
Sbjct: 1545 DTNLVECL--TKINRMDIVHLME 1565


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 35.8 bits (81), Expect = 0.025
 Identities = 19/83 (22%), Positives = 42/83 (50%), Gaps = 2/83 (2%)

Query: 117  DRQINQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQAT 176
            + ++  +A  LG  W  +   L  ++  I++ +  +P+++Q Q       W +R GK AT
Sbjct: 3570 EERLAYIADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERDGKHAT 3629

Query: 177  FQSLHNGLRAVEVDPSLLLHMLE 199
              +L   L   +++   ++H++E
Sbjct: 3630 DTNLVECL--TKINRMDIVHLME 3650


>gi|4502379 B-cell CLL/lymphoma 10 [Homo sapiens]
          Length = 233

 Score = 35.4 bits (80), Expect = 0.032
 Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 7/91 (7%)

Query: 6   KQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDILPSRG 65
           K  L +LR+ L  +++ E     +L  + IL+    +EI+ +T+  ++   LLD L    
Sbjct: 18  KDALENLRVYLCEKIIAERH-FDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYL-QEN 75

Query: 66  PKAFDTFLDSLQEFPWVREKLKKAREEAMTD 96
           PK  DT ++S++     REK +    + +TD
Sbjct: 76  PKGLDTLVESIR-----REKTQNFLIQKITD 101


>gi|4505229 Fas-associated via death domain [Homo sapiens]
          Length = 208

 Score = 34.3 bits (77), Expect = 0.072
 Identities = 17/70 (24%), Positives = 33/70 (47%)

Query: 121 NQLAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSL 180
           N +   +G +W  +   L +S T I   +  +P N+  +V E+   W+    + AT   L
Sbjct: 102 NVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHL 161

Query: 181 HNGLRAVEVD 190
              LR+ +++
Sbjct: 162 VGALRSCQMN 171


>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 33.5 bits (75), Expect = 0.12
 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 7/109 (6%)

Query: 2   EARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDIL 61
           E+ D  ++R  R+ L   +     +L  L   GI+ E     I  +T    +   L+D +
Sbjct: 440 ESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTI 499

Query: 62  PSRGPKAFDTFLDSLQEFP-------WVREKLKKAREEAMTDLPAGDRL 103
             +G  A   F +SLQE         +V++ +K    E ++DLP  ++L
Sbjct: 500 LVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQL 548


>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score = 33.5 bits (75), Expect = 0.12
 Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 7/109 (6%)

Query: 2   EARDKQVLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDIL 61
           E+ D  ++R  R+ L   +     +L  L   GI+ E     I  +T    +   L+D +
Sbjct: 440 ESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDVIKQKTQTSLQARELIDTI 499

Query: 62  PSRGPKAFDTFLDSLQEFP-------WVREKLKKAREEAMTDLPAGDRL 103
             +G  A   F +SLQE         +V++ +K    E ++DLP  ++L
Sbjct: 500 LVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSDLPVEEQL 548


>gi|61742786 leucine rich repeat and death domain containing protein
           isoform 3 [Homo sapiens]
          Length = 893

 Score = 31.2 bits (69), Expect = 0.61
 Identities = 13/48 (27%), Positives = 24/48 (50%)

Query: 123 LAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQR 170
           +A RLG +W  + L LG+S  ++ R +     ++  Q+      W +R
Sbjct: 778 VAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAER 825


>gi|61742784 leucine rich repeat and death domain containing protein
           isoform 1 [Homo sapiens]
          Length = 910

 Score = 31.2 bits (69), Expect = 0.61
 Identities = 13/48 (27%), Positives = 24/48 (50%)

Query: 123 LAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQR 170
           +A RLG +W  + L LG+S  ++ R +     ++  Q+      W +R
Sbjct: 795 VAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAER 842


>gi|61742782 leucine rich repeat and death domain containing protein
           isoform 2 [Homo sapiens]
          Length = 753

 Score = 31.2 bits (69), Expect = 0.61
 Identities = 13/48 (27%), Positives = 24/48 (50%)

Query: 123 LAQRLGPEWEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQR 170
           +A RLG +W  + L LG+S  ++ R +     ++  Q+      W +R
Sbjct: 638 VAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAER 685


>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
           isoform 2 precursor [Homo sapiens]
          Length = 411

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 1/57 (1%)

Query: 131 WEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSLHNGLRAV 187
           WEP++  LGL   +I   KA    + +  +    I+W  + G+ A+  +L + L  +
Sbjct: 325 WEPLMRKLGLMDNEIKVAKAEAAGH-RDTLYTMLIKWVNKTGRDASVHTLLDALETL 380


>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
           isoform 1 precursor [Homo sapiens]
          Length = 440

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 15/57 (26%), Positives = 28/57 (49%), Gaps = 1/57 (1%)

Query: 131 WEPMVLSLGLSQTDIYRCKANHPHNVQSQVVEAFIRWRQRFGKQATFQSLHNGLRAV 187
           WEP++  LGL   +I   KA    + +  +    I+W  + G+ A+  +L + L  +
Sbjct: 354 WEPLMRKLGLMDNEIKVAKAEAAGH-RDTLYTMLIKWVNKTGRDASVHTLLDALETL 409


>gi|7662404 caspase recruitment domain family, member 8 [Homo
           sapiens]
          Length = 431

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 16/53 (30%), Positives = 24/53 (45%)

Query: 26  VLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDILPSRGPKAFDTFLDSLQE 78
           VL  L    +LTEN  + +  + T   K   LL ++  +G  A D    S+ E
Sbjct: 365 VLDDLQDNEVLTENEKELVEQEKTRQSKNEALLSMVEKKGDLALDVLFRSISE 417


>gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]
          Length = 1088

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 19/61 (31%), Positives = 32/61 (52%), Gaps = 3/61 (4%)

Query: 74  DSLQEFPWVREKLKKAREEAMTDLPAGDRL-TGIPSHILNSSPSDRQINQLAQRLGPEWE 132
           +S Q    +RE LK+  + ++  LPAG    T + + +L S  + RQ  Q+  R  P++ 
Sbjct: 14  NSRQRLQEIREGLKQPSKSSVQGLPAGPNSDTSLDAKVLGSKDATRQQQQM--RATPKFG 71

Query: 133 P 133
           P
Sbjct: 72  P 72


>gi|148596998 coiled-coil domain containing 122 [Homo sapiens]
          Length = 273

 Score = 28.9 bits (63), Expect = 3.0
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 2/44 (4%)

Query: 71  TFLDSLQEFPWVREKLKKAREEAMTDL--PAGDRLTGIPSHILN 112
           +F+  L E     +KLK  +EE M DL  P G+R+T +   I N
Sbjct: 147 SFMTELHEKRDFVKKLKTMKEELMQDLQNPGGNRITQVQEDITN 190


>gi|16554562 caspase recruitment domain protein 9 isoform 2 [Homo
          sapiens]
          Length = 492

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)

Query: 8  VLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGL---RKTMLLLDILPSR 64
          VL   R+ L   V+    +  YL Q  +L  +  +++ +    +   RK  +LLDIL   
Sbjct: 13 VLEGFRVTL-TSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRKVGVLLDILQRT 71

Query: 65 GPKAFDTFLDSLQ 77
          G K +  FL+SL+
Sbjct: 72 GHKGYVAFLESLE 84


>gi|47717131 caspase recruitment domain protein 9 isoform 1 [Homo
          sapiens]
          Length = 536

 Score = 28.5 bits (62), Expect = 3.9
 Identities = 22/73 (30%), Positives = 36/73 (49%), Gaps = 4/73 (5%)

Query: 8  VLRSLRLELGAEVLVEGLVLQYLYQEGILTENHIQEINAQTTGL---RKTMLLLDILPSR 64
          VL   R+ L   V+    +  YL Q  +L  +  +++ +    +   RK  +LLDIL   
Sbjct: 13 VLEGFRVTL-TSVIDPSRITPYLRQCKVLNPDDEEQVLSDPNLVIRKRKVGVLLDILQRT 71

Query: 65 GPKAFDTFLDSLQ 77
          G K +  FL+SL+
Sbjct: 72 GHKGYVAFLESLE 84


>gi|169202863 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 527

 Score = 28.1 bits (61), Expect = 5.1
 Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 141 SQTDIYRCKANHPHNVQSQVVEA-FIRWRQRFGKQATFQSLHNGLRAVEVDPSL 193
           S T++YR  +  P   Q  +  +  I W+Q+   Q   +SL  G+RA     S+
Sbjct: 160 SYTNVYRIFSKDPQKSQEVLKNSEIINWKQKLQIQGFQESLGEGIRAAAFSNSV 213


>gi|239744373 PREDICTED: hypothetical protein XP_002343130 [Homo
           sapiens]
          Length = 339

 Score = 28.1 bits (61), Expect = 5.1
 Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 1/54 (1%)

Query: 141 SQTDIYRCKANHPHNVQSQVVEA-FIRWRQRFGKQATFQSLHNGLRAVEVDPSL 193
           S T++YR  +  P   Q  +  +  I W+Q+   Q   +SL  G+RA     S+
Sbjct: 107 SYTNVYRVFSKDPQKSQEVLKNSEIINWKQKLQIQGFQESLGEGIRAAAFSNSV 160


>gi|148727368 bromodomain and PHD finger containing, 3 [Homo
           sapiens]
          Length = 1205

 Score = 28.1 bits (61), Expect = 5.1
 Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 6/56 (10%)

Query: 82  VREKLKKAREEAMTDLPAGDRLTG---IPSHILN---SSPSDRQINQLAQRLGPEW 131
           +++K+KK  EEA  D P+   +     IPS+ LN   S  S ++ NQ  QRL   W
Sbjct: 452 LKQKIKKEPEEAGQDTPSTLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYW 507


>gi|55749600 spire homolog 2 [Homo sapiens]
          Length = 714

 Score = 28.1 bits (61), Expect = 5.1
 Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 6/80 (7%)

Query: 41  IQEINAQTTGLRKTMLLLDILPSRGPKAFDTFLDSLQEFPWVREKLKKAREEAMTDLPAG 100
           +Q+I A+   LRK M+  DI P     A +  LD ++     R  LK+  E  +  LP  
Sbjct: 283 MQDIRARNYKLRKVMVDGDIPPRVKKDAHELILDFIRS----RPPLKQVSERRLRPLPPK 338

Query: 101 DRLTGIPSHILNSSPSDRQI 120
            R   +   IL     +R++
Sbjct: 339 QR--SLHEKILEEIKQERRL 356


>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
          Length = 7081

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 19/132 (14%)

Query: 22   VEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDI-LPSRGPKAFDTFLDSLQEFP 80
            +E L+ Q   ++ +    H   I  +  G ++    LDI L S+G   F T LD+ Q+  
Sbjct: 2960 LEFLIAQRAKEKDVGIAKHSVSIPWEREGSKR----LDIPLNSKGQNIFFTELDTSQQKT 3015

Query: 81   WVREKLKKAREEAMTDLPAGDRLTGIPSHILN----SSPSDRQINQ--LAQRLGPEWEPM 134
               ++L K  + +MT+L +       P H+ N    +   D  IN+   +  LG E    
Sbjct: 3016 CQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE---- 3071

Query: 135  VLSLGLSQTDIY 146
                GL +TDI+
Sbjct: 3072 ----GLKETDIF 3079


>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
          Length = 6929

 Score = 27.7 bits (60), Expect = 6.7
 Identities = 36/132 (27%), Positives = 59/132 (44%), Gaps = 19/132 (14%)

Query: 22   VEGLVLQYLYQEGILTENHIQEINAQTTGLRKTMLLLDI-LPSRGPKAFDTFLDSLQEFP 80
            +E L+ Q   ++ +    H   I  +  G ++    LDI L S+G   F T LD+ Q+  
Sbjct: 2889 LEFLIAQRAKEKDVGIAKHSVSIPWEREGSKR----LDIPLNSKGQNIFFTELDTSQQKT 2944

Query: 81   WVREKLKKAREEAMTDLPAGDRLTGIPSHILN----SSPSDRQINQ--LAQRLGPEWEPM 134
               ++L K  + +MT+L +       P H+ N    +   D  IN+   +  LG E    
Sbjct: 2945 CQEQELLKQEDISMTNLGSMACPIMEPLHLENTGKVTEEEDVYINRKISSHVLGKE---- 3000

Query: 135  VLSLGLSQTDIY 146
                GL +TDI+
Sbjct: 3001 ----GLKETDIF 3008


>gi|51093861 caspase recruitment domain protein 10 [Homo sapiens]
          Length = 1032

 Score = 27.3 bits (59), Expect = 8.8
 Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 3/63 (4%)

Query: 18  AEVLVEGLVLQYLYQEGILTENHIQEINAQ---TTGLRKTMLLLDILPSRGPKAFDTFLD 74
           A  L    +  YL Q  ++ E   +E+ +       + +T  L+DIL  RG + ++ FL+
Sbjct: 39  ARALNPAKLTPYLRQCRVIDEQDEEEVLSTYRFPCRVNRTGRLMDILRCRGKRGYEAFLE 98

Query: 75  SLQ 77
           +L+
Sbjct: 99  ALE 101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,888,492
Number of Sequences: 37866
Number of extensions: 276681
Number of successful extensions: 777
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 763
Number of HSP's gapped (non-prelim): 30
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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