Guide to the Human Genome
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Name: FADD Sequence: fasta or formatted (208aa) NCBI GI: 4505229
Description:

Fas-associated via death domain

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death
TNF and Related Signals

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.7         18           3
 C cysteine            1.9          4           1
 D aspartate           7.2         15           2
 E glutamate           8.2         17           2
 F phenylalanine       2.4          5           1
 G glycine             4.8         10           1
 H histidine           1.9          4           1
 I isoleucine          1.9          4           1
 K lysine              3.8          8           1
 L leucine            14.9         31           2
 M methionine          2.4          5           1
 N asparagine          4.3          9           1
 P proline             2.4          5           1
 Q glutamine           3.8          8           2
 R arginine            9.1         19           2
 S serine             10.1         21           3
 T threonine           3.4          7           1
 V valine              6.7         14           1
 W tryptophan          1.4          3           1
 Y tyrosine            0.5          1           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Fas-associated via death domain 
CASP8                 0.063   caspase 8 isoform G precursor 
CASP8                 0.063   caspase 8 isoform C precursor 
CASP8                 0.063   caspase 8 isoform E 
CASP8                 0.063   caspase 8 isoform C precursor 
CASP8                 0.063   caspase 8 isoform B precursor 
CASP8                 0.063   caspase 8 isoform A precursor 
ANK1                  0.063   ankyrin 1 isoform 9 
ANK1                  0.063   ankyrin 1 isoform 1 
ANK1                  0.063   ankyrin 1 isoform 3 
ANK1                  0.063   ankyrin 1 isoform 4 
ANK1                  0.060   ankyrin 1 isoform 2 
CASP10                0.055   caspase 10 isoform d preproprotein 
CASP10                0.055   caspase 10 isoform b preproprotein 
CASP10                0.055   caspase 10 isoform a preproprotein 
RIPK1                 0.055   receptor (TNFRSF)-interacting serine-threonine kinas...
CFLAR                 0.037   CASP8 and FADD-like apoptosis regulator isoform 2 [...
CFLAR                 0.037   CASP8 and FADD-like apoptosis regulator isoform 1 [...
CFLAR                 0.037   CASP8 and FADD-like apoptosis regulator isoform 1 [...
ANK2                  0.037   ankyrin 2 isoform 3 
ANK2                  0.037   ankyrin 2 isoform 2 
ANK2                  0.037   ankyrin 2 isoform 1 
ANK3                  0.031   ankyrin 3 isoform 2 
ANK3                  0.031   ankyrin 3 isoform 1 
CRADD                 0.023   CASP2 and RIPK1 domain containing adaptor with death ...
DNAH11                0.023   dynein, axonemal, heavy chain 11 
DEDD2                 0.023   death effector domain-containing  DNA binding protei...
KIAA1751              0.018   hypothetical protein LOC85452 
TNFRSF1A              0.016   tumor necrosis factor receptor 1 precursor 
NIN                   0.016   ninein isoform 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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