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Search of human proteins with 4502877
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502877 claudin 4 [Homo sapiens]
(209 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502877 claudin 4 [Homo sapiens] 418 e-117
gi|4502875 claudin 3 [Homo sapiens] 308 3e-84
gi|11141861 claudin 9 [Homo sapiens] 291 4e-79
gi|153792768 claudin 6 [Homo sapiens] 284 4e-77
gi|195947374 claudin 5 [Homo sapiens] 227 6e-60
gi|195947372 claudin 5 [Homo sapiens] 227 6e-60
gi|10863887 claudin 1 [Homo sapiens] 213 7e-56
gi|153792186 claudin 7 [Homo sapiens] 209 1e-54
gi|225703142 claudin 14 [Homo sapiens] 196 1e-50
gi|21536294 claudin 14 [Homo sapiens] 196 1e-50
gi|225703138 claudin 14 [Homo sapiens] 196 1e-50
gi|6912314 claudin 14 [Homo sapiens] 196 1e-50
gi|225703140 claudin 14 [Homo sapiens] 196 1e-50
gi|6912316 claudin 17 [Homo sapiens] 196 2e-50
gi|40788011 claudin 8 [Homo sapiens] 193 8e-50
gi|183979975 claudin 19 isoform b [Homo sapiens] 193 1e-49
gi|183979973 claudin 19 isoform a [Homo sapiens] 189 1e-48
gi|9966781 claudin 2 [Homo sapiens] 173 8e-44
gi|7656981 claudin 15 [Homo sapiens] 139 2e-33
gi|47716519 claudin 20 [Homo sapiens] 137 7e-33
gi|5921465 claudin 10 isoform b [Homo sapiens] 132 2e-31
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 125 3e-29
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 120 1e-27
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 118 4e-27
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 117 7e-27
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 117 7e-27
gi|162417973 claudin 22 [Homo sapiens] 117 7e-27
gi|33598916 claudin 10 isoform a [Homo sapiens] 116 1e-26
gi|157820127 claudin-like [Homo sapiens] 100 9e-22
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 100 9e-22
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 418 bits (1075), Expect = e-117
Identities = 209/209 (100%), Positives = 209/209 (100%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
Query: 181 LCCNCPPRTDKPYSAKYSAARSAAASNYV 209
LCCNCPPRTDKPYSAKYSAARSAAASNYV
Sbjct: 181 LCCNCPPRTDKPYSAKYSAARSAAASNYV 209
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 308 bits (788), Expect = 3e-84
Identities = 145/203 (71%), Positives = 177/203 (87%), Gaps = 4/203 (1%)
Query: 3 SMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQM 62
SMGL++ G ALAVLGWL ++CCALPMWRV+AFIGSNI+TSQ IWEGLWMNCVVQSTGQM
Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
Query: 63 QCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAG 122
QCKVYDSLLALPQDLQAARAL++++I++AA G+L+++VG +CTNC++D++AKAK IVAG
Sbjct: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
Query: 123 VVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLC 182
V+FLLA L+ +VPVSW+A+ II+DFYNP+V QKREMGA LYVGWAA+ L LLGG LLC
Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
Query: 183 CNCPPRTDKPYSAK---YSAARS 202
C+CPPR +K Y+A YSA RS
Sbjct: 182 CSCPPR-EKKYTATKVVYSAPRS 203
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 291 bits (744), Expect = 4e-79
Identities = 133/209 (63%), Positives = 174/209 (83%), Gaps = 3/209 (1%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS GL+++G+ LAVLGWL ++ CALP+W+VTAFIG++IV +Q +WEGLWM+CVVQSTG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QMQCKVYDSLLALPQDLQAARAL +I++++A LG+L+++ G +CT C+EDE AKA+ ++
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
AGV+ LLAG++V++PV WTAH IIQDFYNPLVA KRE+GASLY+GWAA+ LL+LGGGL
Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
Query: 181 LCCNC-PPRTDKPYSAK--YSAARSAAAS 206
LCC C PP+ ++P + YS + AS
Sbjct: 181 LCCTCPPPQVERPRGPRLGYSIPSRSGAS 209
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 284 bits (726), Expect = 4e-77
Identities = 127/206 (61%), Positives = 170/206 (82%), Gaps = 3/206 (1%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS G+Q++G+ L +LGW+ ++ CALPMW+VTAFIG++IV +Q +WEGLWM+CVVQSTG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QMQCKVYDSLLALPQDLQAARAL +I+++VA G+L+ + G KCT C+E++ +KA+ ++
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
+G+VF+++G++ ++PV WTAH II+DFYNPLVA QKRE+GASLY+GWAASGLLLLGGGL
Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
Query: 181 LCCNCP---PRTDKPYSAKYSAARSA 203
LCC CP + Y A+YS + A
Sbjct: 181 LCCTCPSGGSQGPSHYMARYSTSAPA 206
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 227 bits (578), Expect = 6e-60
Identities = 101/209 (48%), Positives = 150/209 (71%), Gaps = 3/209 (1%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
M S L+++G+ L ++GW ++L C LPMW+VTAF+ NIVT+QT W+GLWM+CVVQSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
MQCKVYDS+LAL ++QAARAL + ++++A + + +++ G +CT C+ AKA+ +
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
GV++L GL+ +VP+ W A+ ++++FY+P V QK E+GA+LY+GWAA+ LL++GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCCN---CPPRTDKPYSAKYSAARSAAAS 206
LCC C R D + KYSA R A+
Sbjct: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 227 bits (578), Expect = 6e-60
Identities = 101/209 (48%), Positives = 150/209 (71%), Gaps = 3/209 (1%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
M S L+++G+ L ++GW ++L C LPMW+VTAF+ NIVT+QT W+GLWM+CVVQSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
MQCKVYDS+LAL ++QAARAL + ++++A + + +++ G +CT C+ AKA+ +
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
GV++L GL+ +VP+ W A+ ++++FY+P V QK E+GA+LY+GWAA+ LL++GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCCN---CPPRTDKPYSAKYSAARSAAAS 206
LCC C R D + KYSA R A+
Sbjct: 266 LCCGAWVCTGRPDLSFPVKYSAPRRPTAT 294
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 213 bits (543), Expect = 7e-56
Identities = 97/211 (45%), Positives = 142/211 (67%), Gaps = 2/211 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MA+ GLQ++G LA LGW+ ++ ALP WR+ ++ G NIVT+Q ++EGLWM+CV QSTG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLE-DESAKAKTMI 119
Q+QCKV+DSLL L LQA RAL+++ I++ + + ++ VG KC CLE DE K + +
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
+ G +FLLAGL ++V +W + I+Q+FY+P+ + E G +L+ GWAA+ L LLGG
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 180 LLCCNCPPRTDK-PYSAKYSAARSAAASNYV 209
LLCC+CP +T P Y ++ +YV
Sbjct: 181 LLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV 211
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 209 bits (533), Expect = 1e-54
Identities = 93/208 (44%), Positives = 145/208 (69%), Gaps = 4/208 (1%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MA+ GLQ++G ++A+LGW+ ++ C A+P W+++++ G NI+T+Q +++GLWM+CV QSTG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNC-LEDESAKAKTMI 119
M CK+YDS+LAL LQA RAL+++S+++ L + ++ +G KCT C +D+ KA+ +
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
G++F++AGL +V SW H I+ DFYNPL+ + K E G ++++GWA S L++LGG
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 180 LLCCNCPPRTDKPYSAKYSAARSAAASN 207
LL C+CP K A Y RS SN
Sbjct: 181 LLSCSCPGNESK---AGYRVPRSYPKSN 205
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 196 bits (498), Expect = 1e-50
Identities = 95/205 (46%), Positives = 139/205 (67%), Gaps = 1/205 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS +Q++G L+ LG + ++ LP WR TA +G+NI+T+ + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QC++Y SLLALPQDLQAARAL++IS +++ + +V+G KCT C + AK I+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
G +F+LAGL+ +V VSWT ++++Q+FYNPL+ SG K E+G +LY+G+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCNCPPRTD-KPYSAKYSAARSAA 204
LC +C +PY A A + A
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTA 205
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 196 bits (498), Expect = 1e-50
Identities = 95/205 (46%), Positives = 139/205 (67%), Gaps = 1/205 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS +Q++G L+ LG + ++ LP WR TA +G+NI+T+ + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QC++Y SLLALPQDLQAARAL++IS +++ + +V+G KCT C + AK I+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
G +F+LAGL+ +V VSWT ++++Q+FYNPL+ SG K E+G +LY+G+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCNCPPRTD-KPYSAKYSAARSAA 204
LC +C +PY A A + A
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTA 205
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 196 bits (498), Expect = 1e-50
Identities = 95/205 (46%), Positives = 139/205 (67%), Gaps = 1/205 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS +Q++G L+ LG + ++ LP WR TA +G+NI+T+ + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QC++Y SLLALPQDLQAARAL++IS +++ + +V+G KCT C + AK I+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
G +F+LAGL+ +V VSWT ++++Q+FYNPL+ SG K E+G +LY+G+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCNCPPRTD-KPYSAKYSAARSAA 204
LC +C +PY A A + A
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTA 205
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 196 bits (498), Expect = 1e-50
Identities = 95/205 (46%), Positives = 139/205 (67%), Gaps = 1/205 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS +Q++G L+ LG + ++ LP WR TA +G+NI+T+ + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QC++Y SLLALPQDLQAARAL++IS +++ + +V+G KCT C + AK I+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
G +F+LAGL+ +V VSWT ++++Q+FYNPL+ SG K E+G +LY+G+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCNCPPRTD-KPYSAKYSAARSAA 204
LC +C +PY A A + A
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTA 205
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 196 bits (498), Expect = 1e-50
Identities = 95/205 (46%), Positives = 139/205 (67%), Gaps = 1/205 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS +Q++G L+ LG + ++ LP WR TA +G+NI+T+ + +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QC++Y SLLALPQDLQAARAL++IS +++ + +V+G KCT C + AK I+
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
G +F+LAGL+ +V VSWT ++++Q+FYNPL+ SG K E+G +LY+G+ +S L L+GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCNCPPRTD-KPYSAKYSAARSAA 204
LC +C +PY A A + A
Sbjct: 181 LCLSCQDEAPYRPYQAPPRATTTTA 205
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 196 bits (497), Expect = 2e-50
Identities = 89/186 (47%), Positives = 132/186 (70%), Gaps = 1/186 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MA LQ+ G+ L LG + + LP WRV+AF+GSNI+ + +WEGLWMNC+ Q+
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCL-EDESAKAKTMI 119
++QCK Y SLLALP L+ ARAL+ +++ ++ + +L+ + G K C +E AKA +
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
+GV+F+L G+ V++PVSWTA+ II+DFYNP + GQKRE+GA+L++GWA++ +L +GGG
Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180
Query: 180 LLCCNC 185
LLC C
Sbjct: 181 LLCGFC 186
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 193 bits (491), Expect = 8e-50
Identities = 86/184 (46%), Positives = 130/184 (70%), Gaps = 1/184 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MA+ L++ G+ L +G + + +P WRV+AFI +NIV + WEGLWMNCV Q+
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLED-ESAKAKTMI 119
+MQCK+YDSLLAL DLQAAR L+ + +++ L +++++G KCT C D E KA ++
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
AG++F++ G++V++PVSW A+ II+DFYN +V QKRE+G +LY+GW + +L++GG
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 180 LLCC 183
L CC
Sbjct: 181 LFCC 184
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 193 bits (490), Expect = 1e-49
Identities = 93/211 (44%), Positives = 137/211 (64%), Gaps = 2/211 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MA+ GLQ++G LA+ GW+ ++ ALP W+ +++ G I+T+ ++EGLWM+C QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDES-AKAKTMI 119
Q+QCK+YDSLLAL +Q+ARAL+++++++ + ++LSVVG KCT + AK + I
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
G +F+LAGL + VSW A + Q+F+NP + E G +L+VGWA++GL +LGG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCCNCP-PRTDKPYSAKYSAARSAAASNYV 209
LCC CP P Y SAAA YV
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAAREYV 211
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 189 bits (480), Expect = 1e-48
Identities = 91/207 (43%), Positives = 135/207 (65%), Gaps = 2/207 (0%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MA+ GLQ++G LA+ GW+ ++ ALP W+ +++ G I+T+ ++EGLWM+C QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDES-AKAKTMI 119
Q+QCK+YDSLLAL +Q+ARAL+++++++ + ++LSVVG KCT + AK + I
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGG 179
G +F+LAGL + VSW A + Q+F+NP + E G +L+VGWA++GL +LGG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCCNCP-PRTDKPYSAKYSAARSAAA 205
LCC CP P Y SAAA
Sbjct: 181 FLCCTCPEPERPNSSPQPYRPGPSAAA 207
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 173 bits (439), Expect = 8e-44
Identities = 82/208 (39%), Positives = 133/208 (63%), Gaps = 5/208 (2%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS+GLQ++G L +LG L ++ LP W+ ++++G++IVT+ +GLWM C STG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
QC +Y +LL LP D+QAA+A+++ S +++L ++SVVG +CT ++ AK + +
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
GV F+L GL+ +PV+W H I++DFY+PLV K E+G +LY+G +S L+ G +
Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
Query: 181 LCCNCPPRTDK-----PYSAKYSAARSA 203
LC +C + ++ Y A+ A RS+
Sbjct: 181 LCFSCSSQRNRSNYYDAYQAQPLATRSS 208
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 139 bits (349), Expect = 2e-33
Identities = 80/197 (40%), Positives = 117/197 (59%), Gaps = 5/197 (2%)
Query: 3 SMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQM 62
SM ++ G +A +G L + + WRV+ G N++T+ TI+E LW +C S G
Sbjct: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGVY 60
Query: 63 QCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVA 121
C + S+LAL +QA RAL+I +I++ LG+LL + G +CTN E S KAK A
Sbjct: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
Query: 122 GVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLL 181
G + +LAG+ +V +SW A NI +DF++PL G K E+G +LY+GW+AS + +LGG L
Sbjct: 121 GALHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGLCL 179
Query: 182 C--CNCPPRTDKPYSAK 196
C C C D SA+
Sbjct: 180 CSACCCGSDEDPAASAR 196
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 137 bits (345), Expect = 7e-33
Identities = 68/188 (36%), Positives = 105/188 (55%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS GLQ++ LA+ G V+ LP W+V + SNI+T+ GLWM+C STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
C + S+L+LP +QAARA ++++ +++ALG+ S VG KCT D K+
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
GV F+ AG+ ++ W II +F + V K E G ++Y+G+ ++ LL + G +
Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
Query: 181 LCCNCPPR 188
C +C R
Sbjct: 181 FCTSCIKR 188
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 132 bits (333), Expect = 2e-31
Identities = 70/206 (33%), Positives = 114/206 (55%), Gaps = 3/206 (1%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MAS +++ +++ GW+ V W+V+ G+ ++T+ T W LW CV STG
Sbjct: 1 MASTASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDSTG 59
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
CK + S+LAL +QA R L+I ++ + G + ++ G KCT + AKAK +
Sbjct: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACL 119
Query: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
AG+VF+L+GL + S A+ I +F++PL QK E+GA+L++GWA + L ++GG +
Sbjct: 120 AGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVI 178
Query: 181 LCCNCPPRTDKPYSAKYSAARSAAAS 206
C + P Y+ A S +S
Sbjct: 179 FCFSISDNNKTP-RYTYNGATSVMSS 203
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 125 bits (313), Expect = 3e-29
Identities = 77/221 (34%), Positives = 123/221 (55%), Gaps = 15/221 (6%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
M++ QV+ L++LG + + MW T + N VTS +EGLW +CV QS+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWS-TQDLYDNPVTSVFQYEGLWRSCVRQSSG 59
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNC-LEDESAKAKTMI 119
+C+ Y ++L LP LQA RAL+I+ I++ A+G+L+S+ KC ++SAKA +
Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFY----------NPLVASGQKR-EMGASLYVGW 168
+G++F+++GL I VS A+ ++ +F+ +V + Q R GA+L+VGW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 AASGLLLLGGGLLCCNCPPRTDKPYSAKYSAARSAAASNYV 209
A GL L+GG ++C C R P Y A A+ + V
Sbjct: 180 VAGGLTLIGGVMMCIAC--RGLAPEETNYKAVSYHASGHSV 218
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 120 bits (300), Expect = 1e-27
Identities = 73/221 (33%), Positives = 123/221 (55%), Gaps = 15/221 (6%)
Query: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
MA Q +G ++++G ++ + W T + +N VT+ ++GLW +CV +S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWS-TQDLYNNPVTAVFNYQGLWRSCVRESSG 59
Query: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNC-LEDESAKAKTMI 119
+C+ Y +LL LP LQA RAL+I+ I++ A+G+L+S+ KC ++SAKA +
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 VAGVVFLLAGLMVIVPVSWTAHNIIQDFY----------NPLVASGQKR-EMGASLYVGW 168
+G++F+++GL I VS A+ ++ +F+ +V + Q R GA+L+VGW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 AASGLLLLGGGLLCCNCPPRTDKPYSAKYSAARSAAASNYV 209
A GL L+GG ++C C R P Y A A+ + V
Sbjct: 180 VAGGLTLIGGVMMCIAC--RGLAPEETNYKAVSYHASGHSV 218
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 118 bits (295), Expect = 4e-27
Identities = 67/180 (37%), Positives = 106/180 (58%), Gaps = 5/180 (2%)
Query: 6 LQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCK 65
+Q +G+ L++LGW+ ++ LP W+ + N + + T+ GLW CV+Q MQCK
Sbjct: 9 MQSVGLLLSLLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
Query: 66 VYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVAGVV 124
+DS LALP +L+ +R L+ +S + LG+L+S G C E + K + +I+ G++
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183
+G+ +VPVSW AH +Q+F++ V R E G +L++GW A LLLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 117 bits (293), Expect = 7e-27
Identities = 67/180 (37%), Positives = 105/180 (58%), Gaps = 5/180 (2%)
Query: 6 LQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCK 65
+Q +G+ L+ LGW+ ++ LP W+ + N + + T+ GLW CV+Q MQCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
Query: 66 VYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVAGVV 124
+DS LALP +L+ +R L+ +S + LG+L+S G C E + K + +I+ G++
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183
+G+ +VPVSW AH +Q+F++ V R E G +L++GW A LLLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 117 bits (293), Expect = 7e-27
Identities = 67/180 (37%), Positives = 105/180 (58%), Gaps = 5/180 (2%)
Query: 6 LQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCK 65
+Q +G+ L+ LGW+ ++ LP W+ + N + + T+ GLW CV+Q MQCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65
Query: 66 VYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVAGVV 124
+DS LALP +L+ +R L+ +S + LG+L+S G C E + K + +I+ G++
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 125 FLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183
+G+ +VPVSW AH +Q+F++ V R E G +L++GW A LLLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 117 bits (293), Expect = 7e-27
Identities = 68/179 (37%), Positives = 105/179 (58%), Gaps = 5/179 (2%)
Query: 7 QVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKV 66
Q+ G++L++LGW+ L LP W+ + N + + T+ GLW CV+Q MQCK
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWK-NLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66
Query: 67 YDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDE-SAKAKTMIVAGVVF 125
+DS LALP +L+ +R L+ +S + LG+L+S G C E + K + +I+ G++
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 126 LLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183
+G+ +VPVSW AH +Q+F++ V R E G +L++GW A LLLGG LL C
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHC 185
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 116 bits (291), Expect = 1e-26
Identities = 62/200 (31%), Positives = 110/200 (55%), Gaps = 3/200 (1%)
Query: 7 QVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKV 66
Q+ + V G+ A++ W+VT S+++T+ +++GLWMNC + G C+
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTR-ASSVITATWVYQGLWMNCAGNALGSFHCRP 63
Query: 67 YDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFL 126
+ ++ + +QA R L+I ++ + G + ++ G KCT + AKAK +AG+VF+
Sbjct: 64 HFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 123
Query: 127 LAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCP 186
L+GL + S A+ I +F++PL QK E+GA+L++GWA + L ++GG + C +
Sbjct: 124 LSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSIS 182
Query: 187 PRTDKPYSAKYSAARSAAAS 206
P Y+ A S +S
Sbjct: 183 DNNKTP-RYTYNGATSVMSS 201
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 100 bits (249), Expect = 9e-22
Identities = 63/191 (32%), Positives = 99/191 (51%), Gaps = 6/191 (3%)
Query: 6 LQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCK 65
+Q+ G+ L++LGW+ + LP W+ + + +T G+W CV + CK
Sbjct: 9 VQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATVCK 65
Query: 66 VYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESA-KAKTMIVAGVV 124
++S L+LPQ+LQ AR L++ S + LG+LL G +C K + ++ +
Sbjct: 66 AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
Query: 125 FLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKR-EMGASLYVGWAASGLLLLGGGLLCC 183
A ++PVSW AH IQDF++ + R E G +LY+GWAA L LGG LL
Sbjct: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
Query: 184 N-CPPRTDKPY 193
+ C + D P+
Sbjct: 186 SACLGKEDVPF 196
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 100 bits (249), Expect = 9e-22
Identities = 60/200 (30%), Positives = 102/200 (51%), Gaps = 22/200 (11%)
Query: 7 QVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKV 66
Q+ + V G+ A++ W+VT S+++T+ +++GLWMNC
Sbjct: 5 QIWALVSGVGGFGALVAATTSNEWKVTTR-ASSVITATWVYQGLWMNCAGY--------- 54
Query: 67 YDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGVVFL 126
+QA R L+I ++ + G + ++ G KCT + AKAK +AG+VF+
Sbjct: 55 ----------IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFI 104
Query: 127 LAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCCNCP 186
L+GL + S A+ I +F++PL QK E+GA+L++GWA + L ++GG + C +
Sbjct: 105 LSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSIS 163
Query: 187 PRTDKPYSAKYSAARSAAAS 206
P Y+ A S +S
Sbjct: 164 DNNKTP-RYTYNGATSVMSS 182
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.135 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,130,205
Number of Sequences: 37866
Number of extensions: 264444
Number of successful extensions: 968
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 884
Number of HSP's gapped (non-prelim): 62
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.