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Search of human proteins with 4502875
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502875 claudin 3 [Homo sapiens]
(220 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502875 claudin 3 [Homo sapiens] 442 e-124
gi|4502877 claudin 4 [Homo sapiens] 308 3e-84
gi|11141861 claudin 9 [Homo sapiens] 295 2e-80
gi|153792768 claudin 6 [Homo sapiens] 270 5e-73
gi|195947374 claudin 5 [Homo sapiens] 238 3e-63
gi|195947372 claudin 5 [Homo sapiens] 238 3e-63
gi|10863887 claudin 1 [Homo sapiens] 213 8e-56
gi|153792186 claudin 7 [Homo sapiens] 208 3e-54
gi|40788011 claudin 8 [Homo sapiens] 206 2e-53
gi|6912316 claudin 17 [Homo sapiens] 200 7e-52
gi|225703142 claudin 14 [Homo sapiens] 194 5e-50
gi|21536294 claudin 14 [Homo sapiens] 194 5e-50
gi|225703138 claudin 14 [Homo sapiens] 194 5e-50
gi|6912314 claudin 14 [Homo sapiens] 194 5e-50
gi|225703140 claudin 14 [Homo sapiens] 194 5e-50
gi|183979973 claudin 19 isoform a [Homo sapiens] 192 1e-49
gi|183979975 claudin 19 isoform b [Homo sapiens] 192 1e-49
gi|9966781 claudin 2 [Homo sapiens] 177 8e-45
gi|7656981 claudin 15 [Homo sapiens] 145 3e-35
gi|5921465 claudin 10 isoform b [Homo sapiens] 139 2e-33
gi|47716519 claudin 20 [Homo sapiens] 135 3e-32
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 129 3e-30
gi|33598916 claudin 10 isoform a [Homo sapiens] 124 5e-29
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 122 3e-28
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 115 4e-26
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 114 7e-26
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 114 7e-26
gi|162417973 claudin 22 [Homo sapiens] 112 2e-25
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 108 4e-24
gi|157820127 claudin-like [Homo sapiens] 103 2e-22
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 442 bits (1137), Expect = e-124
Identities = 220/220 (100%), Positives = 220/220 (100%)
Query: 1 MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQ 60
MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQ
Sbjct: 1 MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQ 60
Query: 61 MQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVA 120
MQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVA
Sbjct: 61 MQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVA 120
Query: 121 GVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALL 180
GVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALL
Sbjct: 121 GVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALL 180
Query: 181 CCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220
CCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV
Sbjct: 181 CCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 308 bits (788), Expect = 3e-84
Identities = 145/203 (71%), Positives = 177/203 (87%), Gaps = 4/203 (1%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
SMGL++ G ALAVLGWL ++CCALPMWRV+AFIGSNI+TSQ IWEGLWMNCVVQSTGQM
Sbjct: 3 SMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQM 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QCKVYDSLLALPQDLQAARAL++++I++AA G+L+++VG +CTNC++D++AKAK IVAG
Sbjct: 63 QCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
V+FLLA L+ +VPVSW+A+ II+DFYNP+V QKREMGA LYVGWAA+ L LLGG LLC
Sbjct: 123 VVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLC 182
Query: 182 CSCPPR-EKKYTATKVVYSAPRS 203
C+CPPR +K Y+A YSA RS
Sbjct: 183 CNCPPRTDKPYSAK---YSAARS 202
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 295 bits (755), Expect = 2e-80
Identities = 140/220 (63%), Positives = 178/220 (80%), Gaps = 6/220 (2%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S GLE+ G LAVLGWLGT+V CALP+W+V+AFIG++I+ +Q +WEGLWM+CVVQSTGQM
Sbjct: 3 STGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQM 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QCKVYDSLLALPQDLQAARAL V+A+LLA GLLVA+ GAQCT CV+D+ AKA+I + AG
Sbjct: 63 QCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
V+ LLA +L L+PV W+A+ II+DFYNP+V EA KRE+GA LY+GWAAAAL +LGG LLC
Sbjct: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLC 182
Query: 182 CSCPPRE-KKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220
C+CPP + ++ ++ YS P +G +G D++DYV
Sbjct: 183 CTCPPPQVERPRGPRLGYSIPSRSG-----ASGLDKRDYV 217
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 270 bits (691), Expect = 5e-73
Identities = 130/221 (58%), Positives = 172/221 (77%), Gaps = 5/221 (2%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S G++I G L +LGW+ +V CALPMW+V+AFIG++I+ +Q +WEGLWM+CVVQSTGQM
Sbjct: 3 SAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQM 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QCKVYDSLLALPQDLQAARAL V+A+L+A FGLLV L GA+CT CV++ +KA++ + +G
Sbjct: 63 QCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
++F+++ +LTL+PV W+A+ IIRDFYNP+V EAQKRE+GA LY+GWAA+ L LLGG LLC
Sbjct: 123 IVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLC 182
Query: 182 CSCPPREKKYTATKVVYSAPRST-GPGASLG-TGYDRKDYV 220
C+CP + + Y A ST P S G + Y K+YV
Sbjct: 183 CTCPSGGSQGPSH---YMARYSTSAPAISRGPSEYPTKNYV 220
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 238 bits (607), Expect = 3e-63
Identities = 121/222 (54%), Positives = 153/222 (68%), Gaps = 9/222 (4%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S LEI G L ++GW G I+ C LPMW+V+AF+ NI+T+Q W+GLWM+CVVQSTG M
Sbjct: 88 SAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHM 147
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QCKVYDS+LAL ++QAARAL V A+LLA L V L GAQCT CV AKA++ + G
Sbjct: 148 QCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGG 207
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
VL+L LL LVP+ W AN ++R+FY+P VP +QK E+GA LY+GWAA AL ++GG LLC
Sbjct: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267
Query: 182 CS---CPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220
C C R + V YSAPR P A+ YD+K+YV
Sbjct: 268 CGAWVCTGRPD--LSFPVKYSAPRR--PTAT--GDYDKKNYV 303
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 238 bits (607), Expect = 3e-63
Identities = 121/222 (54%), Positives = 153/222 (68%), Gaps = 9/222 (4%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S LEI G L ++GW G I+ C LPMW+V+AF+ NI+T+Q W+GLWM+CVVQSTG M
Sbjct: 88 SAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHM 147
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QCKVYDS+LAL ++QAARAL V A+LLA L V L GAQCT CV AKA++ + G
Sbjct: 148 QCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGG 207
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
VL+L LL LVP+ W AN ++R+FY+P VP +QK E+GA LY+GWAA AL ++GG LLC
Sbjct: 208 VLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCLLC 267
Query: 182 CS---CPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220
C C R + V YSAPR P A+ YD+K+YV
Sbjct: 268 CGAWVCTGRPD--LSFPVKYSAPRR--PTAT--GDYDKKNYV 303
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 213 bits (543), Expect = 8e-56
Identities = 101/203 (49%), Positives = 136/203 (66%), Gaps = 1/203 (0%)
Query: 4 GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63
GL++ G LA LGW+G IV ALP WR+ ++ G NI+T+Q ++EGLWM+CV QSTGQ+QC
Sbjct: 5 GLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQC 64
Query: 64 KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122
KV+DSLL L LQA RAL+VV ILL + VA VG +C C++DD K ++ ++ G
Sbjct: 65 KVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGA 124
Query: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182
+FLLA L LV +W N I+++FY+P+ P + E G L+ GWAAA+L LLGGALLCC
Sbjct: 125 IFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCC 184
Query: 183 SCPPREKKYTATKVVYSAPRSTG 205
SCP + Y + S+G
Sbjct: 185 SCPRKTTSYPTPRPYPKPAPSSG 207
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 208 bits (530), Expect = 3e-54
Identities = 97/201 (48%), Positives = 139/201 (69%), Gaps = 6/201 (2%)
Query: 4 GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63
GL++ G ++A+LGW+G + C A+P W++S++ G NIIT+Q +++GLWM+CV QSTG M C
Sbjct: 5 GLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSC 64
Query: 64 KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122
K+YDS+LAL LQA RAL+VV+++L + VA +G +CT C DD KA+I + G+
Sbjct: 65 KMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGI 124
Query: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182
+F++A L LV SW + I+ DFYNP++P K E G +++GWA +AL +LGGALL C
Sbjct: 125 IFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSC 184
Query: 183 SCPPREKKYTATKVVYSAPRS 203
SCP E +K Y PRS
Sbjct: 185 SCPGNE-----SKAGYRVPRS 200
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 206 bits (523), Expect = 2e-53
Identities = 104/223 (46%), Positives = 140/223 (62%), Gaps = 10/223 (4%)
Query: 5 LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64
LEI G L +G +GT+ +P WRVSAFI +NI+ +N WEGLWMNCV Q+ +MQCK
Sbjct: 6 LEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCK 65
Query: 65 VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQD-DTAKAKITIVAGVL 123
+YDSLLAL DLQAAR L+ A +++ ++A++G +CT C D + KA I + AG++
Sbjct: 66 IYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGII 125
Query: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCS 183
F++ ++ L+PVSW AN IIRDFYN +V AQKRE+G LY+GW A + ++GGAL CC
Sbjct: 126 FIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCCV 185
Query: 184 CPPREKKYTATKVVYSAPRSTGPGASLGTG------YDRKDYV 220
EK ++ YS P S TG Y R YV
Sbjct: 186 FCCNEK---SSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV 225
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 200 bits (509), Expect = 7e-52
Identities = 97/202 (48%), Positives = 133/202 (65%), Gaps = 3/202 (1%)
Query: 5 LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64
L+I G L LG +GT+ LP WRVSAF+GSNII + +WEGLWMNC+ Q+ ++QCK
Sbjct: 6 LQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCK 65
Query: 65 VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCV-QDDTAKAKITIVAGVL 123
Y SLLALP L+ ARAL+ VA+ L+ LL+ + G + C ++ AKA + +GVL
Sbjct: 66 FYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVL 125
Query: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC-- 181
F+L + L+PVSW+AN IIRDFYNP + QKRE+GA L++GWA+AA+ +GG LLC
Sbjct: 126 FILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGGLLCGF 185
Query: 182 CSCPPREKKYTATKVVYSAPRS 203
C C +++ Y Y P +
Sbjct: 186 CCCNRKKQGYRYPVPGYRVPHT 207
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 194 bits (493), Expect = 5e-50
Identities = 100/237 (42%), Positives = 145/237 (61%), Gaps = 18/237 (7%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S +++ G L+ LG +GT++ LP WR +A +G+NI+T+ + +GLWM CV STG
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QC++Y SLLALPQDLQAARAL+V++ LL+ A++G +CT C + AK I+ G
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
LF+LA LL +V VSW+ N ++++FYNP++P K E+G LY+G+ +++L L+GG LLC
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLC 182
Query: 182 CSC-----------PPREKKYTA-TKVVYSAP------RSTGPGASLGTGYDRKDYV 220
SC PPR TA T Y P R+ ++ +GY DYV
Sbjct: 183 LSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 194 bits (493), Expect = 5e-50
Identities = 100/237 (42%), Positives = 145/237 (61%), Gaps = 18/237 (7%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S +++ G L+ LG +GT++ LP WR +A +G+NI+T+ + +GLWM CV STG
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QC++Y SLLALPQDLQAARAL+V++ LL+ A++G +CT C + AK I+ G
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
LF+LA LL +V VSW+ N ++++FYNP++P K E+G LY+G+ +++L L+GG LLC
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLC 182
Query: 182 CSC-----------PPREKKYTA-TKVVYSAP------RSTGPGASLGTGYDRKDYV 220
SC PPR TA T Y P R+ ++ +GY DYV
Sbjct: 183 LSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 194 bits (493), Expect = 5e-50
Identities = 100/237 (42%), Positives = 145/237 (61%), Gaps = 18/237 (7%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S +++ G L+ LG +GT++ LP WR +A +G+NI+T+ + +GLWM CV STG
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QC++Y SLLALPQDLQAARAL+V++ LL+ A++G +CT C + AK I+ G
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
LF+LA LL +V VSW+ N ++++FYNP++P K E+G LY+G+ +++L L+GG LLC
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLC 182
Query: 182 CSC-----------PPREKKYTA-TKVVYSAP------RSTGPGASLGTGYDRKDYV 220
SC PPR TA T Y P R+ ++ +GY DYV
Sbjct: 183 LSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 194 bits (493), Expect = 5e-50
Identities = 100/237 (42%), Positives = 145/237 (61%), Gaps = 18/237 (7%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S +++ G L+ LG +GT++ LP WR +A +G+NI+T+ + +GLWM CV STG
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QC++Y SLLALPQDLQAARAL+V++ LL+ A++G +CT C + AK I+ G
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
LF+LA LL +V VSW+ N ++++FYNP++P K E+G LY+G+ +++L L+GG LLC
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLC 182
Query: 182 CSC-----------PPREKKYTA-TKVVYSAP------RSTGPGASLGTGYDRKDYV 220
SC PPR TA T Y P R+ ++ +GY DYV
Sbjct: 183 LSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 194 bits (493), Expect = 5e-50
Identities = 100/237 (42%), Positives = 145/237 (61%), Gaps = 18/237 (7%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S +++ G L+ LG +GT++ LP WR +A +G+NI+T+ + +GLWM CV STG
Sbjct: 3 STAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIY 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QC++Y SLLALPQDLQAARAL+V++ LL+ A++G +CT C + AK I+ G
Sbjct: 63 QCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
LF+LA LL +V VSW+ N ++++FYNP++P K E+G LY+G+ +++L L+GG LLC
Sbjct: 123 TLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLC 182
Query: 182 CSC-----------PPREKKYTA-TKVVYSAP------RSTGPGASLGTGYDRKDYV 220
SC PPR TA T Y P R+ ++ +GY DYV
Sbjct: 183 LSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV 239
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 192 bits (489), Expect = 1e-49
Identities = 94/207 (45%), Positives = 136/207 (65%), Gaps = 6/207 (2%)
Query: 4 GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63
GL++ G LA+ GW+G I ALP W+ S++ G IIT+ ++EGLWM+C QSTGQ+QC
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 64 KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122
K+YDSLLAL +Q+ARAL+VVA+LL +++++VG +CT + AK ++ I G
Sbjct: 65 KLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGA 124
Query: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182
LF+LA L TL VSW A + ++F+NP P + E G L+VGWA+A L +LGG+ LCC
Sbjct: 125 LFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCC 184
Query: 183 SCPPREKKYTATKVVYSAPRSTGPGAS 209
+CP E+ ++ + P GP A+
Sbjct: 185 TCPEPERPNSSPQ-----PYRPGPSAA 206
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 192 bits (489), Expect = 1e-49
Identities = 94/207 (45%), Positives = 136/207 (65%), Gaps = 6/207 (2%)
Query: 4 GLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQC 63
GL++ G LA+ GW+G I ALP W+ S++ G IIT+ ++EGLWM+C QSTGQ+QC
Sbjct: 5 GLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQC 64
Query: 64 KVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGV 122
K+YDSLLAL +Q+ARAL+VVA+LL +++++VG +CT + AK ++ I G
Sbjct: 65 KLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGA 124
Query: 123 LFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCC 182
LF+LA L TL VSW A + ++F+NP P + E G L+VGWA+A L +LGG+ LCC
Sbjct: 125 LFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCC 184
Query: 183 SCPPREKKYTATKVVYSAPRSTGPGAS 209
+CP E+ ++ + P GP A+
Sbjct: 185 TCPEPERPNSSPQ-----PYRPGPSAA 206
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 177 bits (448), Expect = 8e-45
Identities = 77/203 (37%), Positives = 130/203 (64%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S+GL++ G L +LG LGT+V LP W+ S+++G++I+T+ +GLWM C STG
Sbjct: 3 SLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGIT 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
QC +Y +LL LP D+QAA+A++V + +++ ++++VG +CT Q+ AK ++ + G
Sbjct: 63 QCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
V F+L LL +PV+W+ + I+RDFY+P+VP++ K E+G LY+G ++ L+ G +LC
Sbjct: 123 VFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILC 182
Query: 182 CSCPPREKKYTATKVVYSAPRST 204
SC + + + P +T
Sbjct: 183 FSCSSQRNRSNYYDAYQAQPLAT 205
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 145 bits (366), Expect = 3e-35
Identities = 85/212 (40%), Positives = 119/212 (56%), Gaps = 5/212 (2%)
Query: 1 MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQ 60
MSM +E G +A +G L V WRVS G N+IT+ I+E LW +C S G
Sbjct: 1 MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHG-NVITTNTIFENLWFSCATDSLGV 59
Query: 61 MQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNC-VQDDTAKAKITIV 119
C + S+LAL +QA RAL++ AILL GLL+ + G +CTN + + KAK+
Sbjct: 60 YNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAAT 119
Query: 120 AGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGAL 179
AG L +LA + +V +SW A I RDF++P+ P K E+G LY+GW+A+ + +LGG
Sbjct: 120 AGALHILAGICGMVAISWYAFNITRDFFDPLYP-GTKYELGPALYLGWSASLISILGGLC 178
Query: 180 LC--CSCPPREKKYTATKVVYSAPRSTGPGAS 209
LC C C E + + Y AP S P A+
Sbjct: 179 LCSACCCGSDEDPAASARRPYQAPVSVMPVAT 210
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 139 bits (350), Expect = 2e-33
Identities = 82/211 (38%), Positives = 120/211 (56%), Gaps = 11/211 (5%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPM--WRVSAFIGSNIITSQNIWEGLWMNCVVQSTG 59
S EI +++ GW+ +V LP W+VS G+ +IT+ W LW CV STG
Sbjct: 3 STASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGT-VITTATYWANLWKACVTDSTG 59
Query: 60 QMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIV 119
CK + S+LAL +QA R L++ A+ L FG + AL G +CT D AKAKI +
Sbjct: 60 VSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACL 119
Query: 120 AGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGAL 179
AG++F+L+ L ++ S AN I +F++P+ E QK E+GA L++GWA A+L ++GG +
Sbjct: 120 AGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVI 178
Query: 180 LCCSCPPREK--KYT---ATKVVYSAPRSTG 205
C S K +YT AT V+ S + G
Sbjct: 179 FCFSISDNNKTPRYTYNGATSVMSSRTKYHG 209
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 135 bits (340), Expect = 3e-32
Identities = 69/186 (37%), Positives = 104/186 (55%)
Query: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
S GL++ LA+ G G + LP W+V+ + SNIIT+ GLWM+C STG
Sbjct: 3 SAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMF 62
Query: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
C + S+L+LP +QAARA +V+A +L+A G+ + VG +CT D K+ + G
Sbjct: 63 SCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFAGG 122
Query: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
V F+ A + +L+ W II +F + VPE+ K E G +Y+G+ +A L + G + C
Sbjct: 123 VCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMIFC 182
Query: 182 CSCPPR 187
SC R
Sbjct: 183 TSCIKR 188
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 129 bits (323), Expect = 3e-30
Identities = 80/232 (34%), Positives = 123/232 (53%), Gaps = 20/232 (8%)
Query: 6 EITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKV 65
++ L++LG G I + MW N +TS +EGLW +CV QS+G +C+
Sbjct: 7 QVVAFLLSILGLAGCIAATGMDMWSTQDLY-DNPVTSVFQYEGLWRSCVRQSSGFTECRP 65
Query: 66 YDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNC-VQDDTAKAKITIVAGVLF 124
Y ++L LP LQA RAL++V I+L A GLLV++ +C +D+AKA +T+ +G++F
Sbjct: 66 YFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMF 125
Query: 125 LLAALLTLVPVSWSANTIIRDFY----------NPVVPEAQKR-EMGAGLYVGWAAAALQ 173
+++ L + VS AN ++ +F+ +V Q R GA L+VGW A L
Sbjct: 126 IVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLT 185
Query: 174 LLGGALLCCSC---PPREKKYTATKVVYS----APRSTGPGASLGTGYDRKD 218
L+GG ++C +C P E Y A S A + G AS G G + K+
Sbjct: 186 LIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKN 237
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 124 bits (312), Expect = 5e-29
Identities = 70/197 (35%), Positives = 113/197 (57%), Gaps = 8/197 (4%)
Query: 15 LGWLGTIVCCALPM-WRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALP 73
+G G +V W+V+ S++IT+ +++GLWMNC + G C+ + ++ +
Sbjct: 13 VGGFGALVAATTSNEWKVTTR-ASSVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVA 71
Query: 74 QDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLV 133
+QA R L++ A+ L FG + AL G +CT D AKAKI +AG++F+L+ L ++
Sbjct: 72 GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMT 131
Query: 134 PVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREK--KY 191
S AN I +F++P+ E QK E+GA L++GWA A+L ++GG + C S K +Y
Sbjct: 132 GCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRY 190
Query: 192 T---ATKVVYSAPRSTG 205
T AT V+ S + G
Sbjct: 191 TYNGATSVMSSRTKYHG 207
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 122 bits (305), Expect = 3e-28
Identities = 76/229 (33%), Positives = 122/229 (53%), Gaps = 20/229 (8%)
Query: 9 GTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDS 68
G ++++G G I + W +N +T+ ++GLW +CV +S+G +C+ Y +
Sbjct: 10 GFVVSLIGIAGIIAATCMDQWSTQDLY-NNPVTAVFNYQGLWRSCVRESSGFTECRGYFT 68
Query: 69 LLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNC-VQDDTAKAKITIVAGVLFLLA 127
LL LP LQA RAL++V I+L A GLLV++ +C +D+AKA +T+ +G++F+++
Sbjct: 69 LLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVS 128
Query: 128 ALLTLVPVSWSANTIIRDFY----------NPVVPEAQKR-EMGAGLYVGWAAAALQLLG 176
L + VS AN ++ +F+ +V Q R GA L+VGW A L L+G
Sbjct: 129 GLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIG 188
Query: 177 GALLCCSC---PPREKKYTATKVVYS----APRSTGPGASLGTGYDRKD 218
G ++C +C P E Y A S A + G AS G G + K+
Sbjct: 189 GVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKN 237
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 115 bits (287), Expect = 4e-26
Identities = 64/181 (35%), Positives = 102/181 (56%), Gaps = 5/181 (2%)
Query: 5 LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64
++ G L++LGW+ +I+ LP W+ + ++ +N GLW CV+Q MQCK
Sbjct: 9 MQSVGLLLSLLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 65 VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVL 123
+DS LALP +L+ +R L+ ++ L GLLV+ G C + K ++ I+ G+L
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCC 182
+ + LVPVSW A+ +++F++ VP+ R E G L++GW A LLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 S 183
+
Sbjct: 186 A 186
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 114 bits (285), Expect = 7e-26
Identities = 64/181 (35%), Positives = 101/181 (55%), Gaps = 5/181 (2%)
Query: 5 LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64
++ G L+ LGW+ +I+ LP W+ + ++ +N GLW CV+Q MQCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 65 VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVL 123
+DS LALP +L+ +R L+ ++ L GLLV+ G C + K ++ I+ G+L
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCC 182
+ + LVPVSW A+ +++F++ VP+ R E G L++GW A LLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 S 183
+
Sbjct: 186 A 186
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 114 bits (285), Expect = 7e-26
Identities = 64/181 (35%), Positives = 101/181 (55%), Gaps = 5/181 (2%)
Query: 5 LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64
++ G L+ LGW+ +I+ LP W+ + ++ +N GLW CV+Q MQCK
Sbjct: 9 MQSVGLLLSFLGWILSIITTYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCK 65
Query: 65 VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVL 123
+DS LALP +L+ +R L+ ++ L GLLV+ G C + K ++ I+ G+L
Sbjct: 66 DFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125
Query: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCC 182
+ + LVPVSW A+ +++F++ VP+ R E G L++GW A LLGG LL C
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLNC 185
Query: 183 S 183
+
Sbjct: 186 A 186
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 112 bits (281), Expect = 2e-25
Identities = 63/180 (35%), Positives = 102/180 (56%), Gaps = 5/180 (2%)
Query: 6 EITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKV 65
++ G +L++LGW+ + + LP W+ + ++ +N GLW CV+Q MQCK
Sbjct: 10 QLAGVSLSLLGWVLSCLTNYLPHWKN---LNLDLNEMENWTMGLWQTCVIQEEVGMQCKD 66
Query: 66 YDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVLF 124
+DS LALP +L+ +R L+ ++ L GLLV+ G C + K ++ I+ G+L
Sbjct: 67 FDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILS 126
Query: 125 LLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCCS 183
+ + LVPVSW A+ +++F++ VP+ R E G L++GW A LLGG LL C+
Sbjct: 127 WASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCA 186
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 108 bits (270), Expect = 4e-24
Identities = 68/197 (34%), Positives = 105/197 (53%), Gaps = 27/197 (13%)
Query: 15 LGWLGTIVCCALPM-WRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALP 73
+G G +V W+V+ S++IT+ +++GLWMNC
Sbjct: 13 VGGFGALVAATTSNEWKVTTR-ASSVITATWVYQGLWMNCAGY----------------- 54
Query: 74 QDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLV 133
+QA R L++ A+ L FG + AL G +CT D AKAKI +AG++F+L+ L ++
Sbjct: 55 --IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMT 112
Query: 134 PVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREK--KY 191
S AN I +F++P+ E QK E+GA L++GWA A+L ++GG + C S K +Y
Sbjct: 113 GCSLYANKITTEFFDPLFVE-QKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRY 171
Query: 192 T---ATKVVYSAPRSTG 205
T AT V+ S + G
Sbjct: 172 TYNGATSVMSSRTKYHG 188
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 103 bits (256), Expect = 2e-22
Identities = 61/181 (33%), Positives = 97/181 (53%), Gaps = 5/181 (2%)
Query: 5 LEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCK 64
+++ G L++LGW+ + V LP W+ + + + G+W CV + CK
Sbjct: 9 VQLGGLLLSLLGWVCSCVTTILPQWKT---LNLELNEMETWIMGIWEVCVDREEVATVCK 65
Query: 65 VYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDD-TAKAKITIVAGVL 123
++S L+LPQ+LQ AR L+V + L GLL+ G++C + K ++ ++ L
Sbjct: 66 AFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTL 125
Query: 124 FLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKR-EMGAGLYVGWAAAALQLLGGALLCC 182
A+ TL+PVSW A+ I+DF++ +P+ R E G LY+GWAA LGG LL
Sbjct: 126 EASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLLIF 185
Query: 183 S 183
S
Sbjct: 186 S 186
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.136 0.426
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,202,744
Number of Sequences: 37866
Number of extensions: 331721
Number of successful extensions: 1188
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 36
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1106
Number of HSP's gapped (non-prelim): 57
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.