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Search of human proteins with 4502619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
(292 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 587 e-168
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 419 e-117
gi|4502617 cyclin D2 [Homo sapiens] 351 4e-97
gi|209915553 cyclin D3 isoform 3 [Homo sapiens] 348 2e-96
gi|16950655 cyclin D1 [Homo sapiens] 295 3e-80
gi|209915556 cyclin D3 isoform 4 [Homo sapiens] 189 2e-48
gi|161377472 cyclin A1 isoform c [Homo sapiens] 101 7e-22
gi|161377470 cyclin A1 isoform c [Homo sapiens] 101 7e-22
gi|161377468 cyclin A1 isoform b [Homo sapiens] 101 7e-22
gi|4502611 cyclin A1 isoform a [Homo sapiens] 101 7e-22
gi|4502613 cyclin A [Homo sapiens] 95 8e-20
gi|17318565 cyclin E2 [Homo sapiens] 86 3e-17
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 79 5e-15
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 79 5e-15
gi|14327896 cyclin B1 [Homo sapiens] 79 5e-15
gi|4757930 cyclin B2 [Homo sapiens] 77 1e-14
gi|153791755 cyclin domain containing [Homo sapiens] 65 7e-11
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 56 3e-08
gi|197276674 cyclin J isoform 1 [Homo sapiens] 55 6e-08
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 54 2e-07
gi|40805832 cyclin G1 [Homo sapiens] 52 5e-07
gi|4757934 cyclin G1 [Homo sapiens] 52 5e-07
gi|5802992 cyclin I [Homo sapiens] 47 2e-05
gi|4757936 cyclin G2 [Homo sapiens] 45 6e-05
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 44 2e-04
gi|89886237 cyclin I family, member 2 [Homo sapiens] 43 4e-04
gi|118572588 cyclin F [Homo sapiens] 42 5e-04
gi|40254889 cyclin J isoform 2 [Homo sapiens] 41 0.001
gi|197276676 cyclin J isoform 3 [Homo sapiens] 40 0.002
gi|94680985 cyclin J-like [Homo sapiens] 39 0.004
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 587 bits (1514), Expect = e-168
Identities = 292/292 (100%), Positives = 292/292 (100%)
Query: 1 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 60
MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML
Sbjct: 1 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 60
Query: 61 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT 120
AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT
Sbjct: 61 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT 120
Query: 121 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 180
IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK
Sbjct: 121 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 180
Query: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL 240
HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL
Sbjct: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL 240
Query: 241 RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292
RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 241 RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 419 bits (1076), Expect = e-117
Identities = 211/211 (100%), Positives = 211/211 (100%)
Query: 82 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 141
MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
Query: 142 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 201
VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS
Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPS 120
Query: 202 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 261
MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT
Sbjct: 121 MIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 180
Query: 262 SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292
SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 181 SSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 211
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 351 bits (901), Expect = 4e-97
Identities = 183/297 (61%), Positives = 227/297 (76%), Gaps = 13/297 (4%)
Query: 1 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 60
MELLC E RA D LL D RVLQ+LL +EERY+P+ SYF+CVQ++I+P+MR+M+
Sbjct: 1 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV 59
Query: 61 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT 120
A WMLEVCEEQ+CEEEVFPLAMNYLDR+L+ VPT K+ LQLLGAVCM LASKL+ET+PLT
Sbjct: 60 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT 119
Query: 121 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 180
EKLCIYTD+++ P++L +WE++VLGKLKW+LAAV HDF+ IL +L R++ +L++K
Sbjct: 120 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK 179
Query: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGL----GACSMSGDELTELLAGITGTE 236
HAQTF+ALCATD+ FAMYPPSMIATGS+GAA+ GL S++ D LTELLA IT T+
Sbjct: 180 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD 239
Query: 237 VDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 292
VDCL+ACQEQIEA L SL++ Q GS S+ Q STPTDV I L
Sbjct: 240 VDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL 289
>gi|209915553 cyclin D3 isoform 3 [Homo sapiens]
Length = 220
Score = 348 bits (894), Expect = 2e-96
Identities = 199/292 (68%), Positives = 201/292 (68%), Gaps = 72/292 (24%)
Query: 1 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 60
MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLL
Sbjct: 1 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLL---------------------------- 32
Query: 61 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT 120
R EE P A Y CV RE P
Sbjct: 33 -----------RLEERYVPRAS-----YFQCVQ--------------------REIKPHM 56
Query: 121 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 180
+ L + L DWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK
Sbjct: 57 RKMLAYW--------MLEDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 108
Query: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL 240
HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL
Sbjct: 109 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL 168
Query: 241 RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292
RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 169 RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 220
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 295 bits (755), Expect = 3e-80
Identities = 153/295 (51%), Positives = 200/295 (67%), Gaps = 7/295 (2%)
Query: 2 ELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLA 61
+LLCCE RA PD LL D RVL+++L+ EE P SYF+CVQ+E+ P MRK++A
Sbjct: 4 QLLCCE-VETIRRAYPDANLLND-RVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKIVA 61
Query: 62 YWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTI 121
WMLEVCEEQ+CEEEVFPLAMNYLDR+LS P +K++LQLLGA CM +ASK++ET PLT
Sbjct: 62 TWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTA 121
Query: 122 EKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKH 181
EKLCIYTD+++ P +L E+L++ KLKW+LAA+ HDF+ L ++ + + +++KH
Sbjct: 122 EKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIRKH 181
Query: 182 AQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACS----MSGDELTELLAGITGTEV 237
AQTF+ALCATD F PPSM+A GS+ AAVQGL S +S LT L+ + +
Sbjct: 182 AQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKCDP 241
Query: 238 DCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292
DCLRACQEQIEA L SLR+A Q + P + TPTDV + +
Sbjct: 242 DCLRACQEQIEALLESSLRQAQQ-NMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 295
>gi|209915556 cyclin D3 isoform 4 [Homo sapiens]
Length = 96
Score = 189 bits (481), Expect = 2e-48
Identities = 96/96 (100%), Positives = 96/96 (100%)
Query: 197 MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 256
MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR
Sbjct: 1 MYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLR 60
Query: 257 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 292
EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL
Sbjct: 61 EASQTSSSPAPKAPRGSSSQGPSQTSTPTDVTAIHL 96
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 101 bits (252), Expect = 7e-22
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 9/226 (3%)
Query: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84
+ + Q L E R+ P+A Y + Q +I MR +L W++EV EE + E LA+N+
Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227
Query: 85 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 144
LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E L+
Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287
Query: 145 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204
L L +DL + FL L R + + L K A+ L+L D F Y PS+IA
Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344
Query: 205 TGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 250
AA L +++ E LA TG + + C ++ A
Sbjct: 345 -----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 385
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 101 bits (252), Expect = 7e-22
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 9/226 (3%)
Query: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84
+ + Q L E R+ P+A Y + Q +I MR +L W++EV EE + E LA+N+
Sbjct: 169 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227
Query: 85 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 144
LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E L+
Sbjct: 228 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 287
Query: 145 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204
L L +DL + FL L R + + L K A+ L+L D F Y PS+IA
Sbjct: 288 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 344
Query: 205 TGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 250
AA L +++ E LA TG + + C ++ A
Sbjct: 345 -----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 385
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 101 bits (252), Expect = 7e-22
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 9/226 (3%)
Query: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84
+ + Q L E R+ P+A Y + Q +I MR +L W++EV EE + E LA+N+
Sbjct: 212 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 270
Query: 85 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 144
LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E L+
Sbjct: 271 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 330
Query: 145 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204
L L +DL + FL L R + + L K A+ L+L D F Y PS+IA
Sbjct: 331 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 387
Query: 205 TGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 250
AA L +++ E LA TG + + C ++ A
Sbjct: 388 -----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 428
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 101 bits (252), Expect = 7e-22
Identities = 76/226 (33%), Positives = 112/226 (49%), Gaps = 9/226 (3%)
Query: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84
+ + Q L E R+ P+A Y + Q +I MR +L W++EV EE + E LA+N+
Sbjct: 213 EEIYQYLREAEIRHRPKAHYMK-KQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271
Query: 85 LDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLV 144
LDR+LSC+ + +LQL+G MLLASK E P +++ TD + RQL E L+
Sbjct: 272 LDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLL 331
Query: 145 LGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204
L L +DL + FL L R + + L K A+ L+L D F Y PS+IA
Sbjct: 332 LKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAE--LSLLEAD-PFLKYLPSLIA 388
Query: 205 TGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAA 250
AA L +++ E LA TG + + C ++ A
Sbjct: 389 -----AAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKA 429
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 94.7 bits (234), Expect = 8e-20
Identities = 73/232 (31%), Positives = 116/232 (50%), Gaps = 10/232 (4%)
Query: 31 LLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLS 90
L +E + P+ Y + Q +I MR +L W++EV EE + + E LA+NY+DR+LS
Sbjct: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244
Query: 91 CVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKW 150
+ + +LQL+G MLLASK E P + + TD + +Q+ E LVL L +
Sbjct: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304
Query: 151 DLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIG 209
DLAA + FL + LH+ ++L + L+L D + Y PS+IA G
Sbjct: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIA----G 357
Query: 210 AAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 261
AA L +++G E L TG ++ L+ C + ++ + A Q+
Sbjct: 358 AAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQS 408
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 86.3 bits (212), Expect = 3e-17
Identities = 64/233 (27%), Positives = 111/233 (47%), Gaps = 9/233 (3%)
Query: 13 PRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQR 72
P PD + V ++L+ E RYV +F+ + +++P MR +L W+LEVCE
Sbjct: 99 PSPLPDLSWGCSKEVWLNMLKKESRYV-HDKHFEVLHSDLEPQMRSILLDWLLEVCEVYT 157
Query: 73 CEEEVFPLAMNYLDRY-LSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHA 131
E F LA ++ DR+ L+ K LQL+G + +ASKL E +++ TD A
Sbjct: 158 LHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGA 217
Query: 132 VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQ-TFLALCA 190
S + E+++L LKW+L V +L L +L + L+ +++Q TF+ +
Sbjct: 218 CSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIA- 276
Query: 191 TDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRAC 243
+ ++A S+ + L A ++ E++ +G E D + C
Sbjct: 277 -----QLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISEC 324
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 79.0 bits (193), Expect = 5e-15
Identities = 55/193 (28%), Positives = 98/193 (50%), Gaps = 11/193 (5%)
Query: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84
+ V + +L E+ Y+ R +F ++P MR +L W++EVCE + E F LA ++
Sbjct: 114 EEVWKIMLNKEKTYL-RDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDF 172
Query: 85 LDRYLSCVP-TRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVL 143
DRY++ K LQL+G + +A+KL E P + + TD A S ++ E++
Sbjct: 173 FDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELM 232
Query: 144 VLGKLKWDLAAVIAHDFL------AFI--LHRLSLPRDRQALVKKHAQTFLALCATDYTF 195
++ LKW L+ + +L A++ LH + LP+ Q + + A+ L LC D
Sbjct: 233 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAE-LLDLCVLDVDC 291
Query: 196 AMYPPSMIATGSI 208
+P ++A ++
Sbjct: 292 LEFPYGILAASAL 304
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 79.0 bits (193), Expect = 5e-15
Identities = 55/193 (28%), Positives = 98/193 (50%), Gaps = 11/193 (5%)
Query: 25 QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNY 84
+ V + +L E+ Y+ R +F ++P MR +L W++EVCE + E F LA ++
Sbjct: 99 EEVWKIMLNKEKTYL-RDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDF 157
Query: 85 LDRYLSCVP-TRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVL 143
DRY++ K LQL+G + +A+KL E P + + TD A S ++ E++
Sbjct: 158 FDRYMATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELM 217
Query: 144 VLGKLKWDLAAVIAHDFL------AFI--LHRLSLPRDRQALVKKHAQTFLALCATDYTF 195
++ LKW L+ + +L A++ LH + LP+ Q + + A+ L LC D
Sbjct: 218 IMKALKWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAE-LLDLCVLDVDC 276
Query: 196 AMYPPSMIATGSI 208
+P ++A ++
Sbjct: 277 LEFPYGILAASAL 289
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 79.0 bits (193), Expect = 5e-15
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 16/204 (7%)
Query: 16 GPDPRLLGD--QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRC 73
G DP L + + + L +LEE R Y + RE+ +MR +L W+++V + R
Sbjct: 161 GADPNLCSEYVKDIYAYLRQLEEEQAVRPKYL--LGREVTGNMRAILIDWLVQVQMKFRL 218
Query: 74 EEEVFPLAMNYLDRYL--SCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHA 131
+E + ++ +DR++ +CVP K LQL+G M +ASK E P I TD+
Sbjct: 219 LQETMYMTVSIIDRFMQNNCVP--KKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNT 276
Query: 132 VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKH--AQTFLALC 189
+ Q+R E+ +L L + L + F L R S + + V++H A+ + L
Sbjct: 277 YTKHQIRQMEMKILRALNFGLGRPLPLHF----LRRAS--KIGEVDVEQHTLAKYLMELT 330
Query: 190 ATDYTFAMYPPSMIATGSIGAAVQ 213
DY +PPS IA G+ A++
Sbjct: 331 MLDYDMVHFPPSQIAAGAFCLALK 354
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 77.4 bits (189), Expect = 1e-14
Identities = 50/167 (29%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Query: 50 REIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLL 109
R+I MR +L W+++V + R +E + + +DR+L P + +LQL+G +LL
Sbjct: 159 RDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLL 218
Query: 110 ASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLS 169
ASK E IE TD+A + Q+R+ E L+L +LK++L + F L R S
Sbjct: 219 ASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLPLHF----LRRAS 274
Query: 170 LPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG 216
+ A+ + L DY Y PS +A + + + LG
Sbjct: 275 KAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLG 321
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 65.1 bits (157), Expect = 7e-11
Identities = 54/178 (30%), Positives = 79/178 (44%), Gaps = 14/178 (7%)
Query: 35 EERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPT 94
E + PR + + Q ++ R L W++ V + E L +N LDR+L+ P
Sbjct: 113 ESHFHPREALAR--QPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRFLTTTPV 170
Query: 95 RKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAA 154
QLLG +L+A K E P +++L A S +QL + E +VL KL + L A
Sbjct: 171 AADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTLGA 230
Query: 155 VIAHDFLAFILH--------RLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIA 204
FL H S + QAL + A+ LA DY F Y PS++A
Sbjct: 231 PTISFFLEHFTHARVEAGQAEASEALEAQALARGVAELSLA----DYAFTSYSPSLLA 284
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 56.2 bits (134), Expect = 3e-08
Identities = 35/113 (30%), Positives = 53/113 (46%)
Query: 49 QREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCML 108
Q EI MR +L W++EV E LA+ +D YL +K +LQLLGA +
Sbjct: 1153 QIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFM 1212
Query: 109 LASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFL 161
+A+K E ++ D ++ E+ +L LK D+ IA+ FL
Sbjct: 1213 IAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILNVLKCDINIPIAYHFL 1265
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 55.5 bits (132), Expect = 6e-08
Identities = 58/224 (25%), Positives = 94/224 (41%), Gaps = 23/224 (10%)
Query: 80 LAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVS 133
LA+ LD ++ QL L+ C+LLASK +E + +E+L C+ + V
Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
Query: 134 PRQ-LRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRD------------RQALVKK 180
+Q L E+L+L +W+L A F+ + L D + + K
Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182
Query: 181 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCL 240
+A FL + DY F Y PS++A + ++ L L L T D L
Sbjct: 183 YADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRL----TAYSWDFL 238
Query: 241 RACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 284
C E++ A ++EA++ P++ + S Q SQ S P
Sbjct: 239 VQCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 282
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 53.9 bits (128), Expect = 2e-07
Identities = 35/117 (29%), Positives = 57/117 (48%)
Query: 36 ERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTR 95
E V R + + R + P MR ++ W+++V E + LA++ LD YLS R
Sbjct: 87 EVMVCRVLPLRALPRAVTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVR 146
Query: 96 KAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDL 152
+LQLLG C+ +A K+ E LC+ + + S +L E +L +L + L
Sbjct: 147 LHRLQLLGVACLFVACKMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 52.4 bits (124), Expect = 5e-07
Identities = 59/239 (24%), Positives = 101/239 (42%), Gaps = 17/239 (7%)
Query: 28 LQSLLRLEERYVPRASYFQCVQR------EIKPHMRKMLAYWMLEVCEEQRCEEEVFPLA 81
L +LL E R P+ + ++ + +R +L + + + E F LA
Sbjct: 17 LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76
Query: 82 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 138
+N LDR+LS + + L +G C LA K E PL + + I + + + L
Sbjct: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135
Query: 139 DWEVLVLGKLKWDLAAVIAHDFLA--FILHRLSLPRDRQALVK-KHAQTFLALCATDYTF 195
E +VL K+ W + A A FL + L + +LP +R+ + + + L C F
Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIF 195
Query: 196 AMYPPSMIATGSIGAAVQGLGACSMS-GDELTELLAGITGTEVDCLRACQEQIEAALRE 253
+ PS++A I +Q ++ G E + + I G + L QE + L E
Sbjct: 196 SKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRD---LTFWQELVSKCLTE 251
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 52.4 bits (124), Expect = 5e-07
Identities = 59/239 (24%), Positives = 101/239 (42%), Gaps = 17/239 (7%)
Query: 28 LQSLLRLEERYVPRASYFQCVQR------EIKPHMRKMLAYWMLEVCEEQRCEEEVFPLA 81
L +LL E R P+ + ++ + +R +L + + + E F LA
Sbjct: 17 LNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLA 76
Query: 82 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDHAVSPRQLR 138
+N LDR+LS + + L +G C LA K E PL + + I + + + L
Sbjct: 77 VNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRI-SQYRFTVSDLM 135
Query: 139 DWEVLVLGKLKWDLAAVIAHDFLA--FILHRLSLPRDRQALVK-KHAQTFLALCATDYTF 195
E +VL K+ W + A A FL + L + +LP +R+ + + + L C F
Sbjct: 136 RMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIF 195
Query: 196 AMYPPSMIATGSIGAAVQGLGACSMS-GDELTELLAGITGTEVDCLRACQEQIEAALRE 253
+ PS++A I +Q ++ G E + + I G + L QE + L E
Sbjct: 196 SKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRD---LTFWQELVSKCLTE 251
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 47.4 bits (111), Expect = 2e-05
Identities = 34/130 (26%), Positives = 57/130 (43%), Gaps = 3/130 (2%)
Query: 50 REIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLL 109
+ + P R + W+ ++ + E F LA + LDR+L+ V L + C L
Sbjct: 38 QNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFL 97
Query: 110 ASK-LRETTPLTIEKLCIYTDH-AVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHR 167
A+K + E + + K+ S ++ E ++L KL WDL DFL I H
Sbjct: 98 AAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFL-HIFHA 156
Query: 168 LSLPRDRQAL 177
+++ Q L
Sbjct: 157 IAVSTRPQLL 166
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/223 (25%), Positives = 96/223 (43%), Gaps = 24/223 (10%)
Query: 20 RLLGDQRVLQSLLRLEERYVPRASYFQCVQ------REIKPHMRKMLAYWMLEVCEEQRC 73
+LLG +L L EER+ PR ++ + P +R + +
Sbjct: 16 QLLG---LLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGS 72
Query: 74 EEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRE---TTPLTIEKLCIYTDH 130
E F LA+N LDR+L+ + + L +G LLA+++ E P T + + I +
Sbjct: 73 CTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRI-SQC 131
Query: 131 AVSPRQLRDWEVLVLGKLKWDLAAVIAHDFL----AFILHRLSLPRDRQALVKKHAQTFL 186
+ ++ E ++ KL ++L A A +FL IL S ++ +L K AQ L
Sbjct: 132 KCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQ--L 189
Query: 187 ALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELL 229
C F+ PS++A + V+ ++ EL E+L
Sbjct: 190 KACNCRLIFSKAKPSVLALCLLNLEVE-----TLKSVELLEIL 227
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 43.9 bits (102), Expect = 2e-04
Identities = 26/86 (30%), Positives = 41/86 (47%)
Query: 76 EVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPR 135
E LA+ +D YL +K +LQLLGA ++A+K E ++ D
Sbjct: 76 ETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRS 135
Query: 136 QLRDWEVLVLGKLKWDLAAVIAHDFL 161
++ E+ +L LK D+ IA+ FL
Sbjct: 136 EVLSMEINILNVLKCDINIPIAYHFL 161
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 42.7 bits (99), Expect = 4e-04
Identities = 70/276 (25%), Positives = 112/276 (40%), Gaps = 28/276 (10%)
Query: 12 APRAGPDPR----LLGD--QRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWML 65
APR P R L GD +R L L+L + R Q EI +++ W+L
Sbjct: 100 APRPAPQSRKPRNLEGDLDERRLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVL-WLL 158
Query: 66 EVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLC 125
+ + F LA+ R L V ++ L + LA+K+ E I ++
Sbjct: 159 RLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEF-IPQVK 217
Query: 126 IYTDHA---VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFI--LHRLSLPRDRQALVKK 180
+T H SP +L E+ +L +L WDL DFL L LS P + L ++
Sbjct: 218 DFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQR 277
Query: 181 HAQTFLAL-------CATDYTFAMYPPSMIATGSIGAAVQGL--GACSMSGDELTELLAG 231
+ +A C + + S +A I ++ L G C+ D L + A
Sbjct: 278 NPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKK--AQ 335
Query: 232 ITGTEVDCLRACQEQIEAALRESLREASQTSSSPAP 267
+ + C C+E + LR SL+ +S T + +P
Sbjct: 336 VGDMQYSC---CKELVMQQLR-SLQSSSCTDNFVSP 367
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 42.4 bits (98), Expect = 5e-04
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 6/162 (3%)
Query: 48 VQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCM 107
VQ+ + MR +L W++EV + L + +DRYL + +LQLLG CM
Sbjct: 301 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM 360
Query: 108 LLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHR 167
++ ++ LTI + TD+ L ++ L+ + D+ +L
Sbjct: 361 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL 420
Query: 168 LSLPRDRQALVKKHAQTFLA-LCATDYTFAMYPPSMIATGSI 208
+ + L +H +FL L + + Y P+ +A ++
Sbjct: 421 VPV-----ELRTQHLCSFLCELSLLHTSLSAYAPARLAAAAL 457
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 41.2 bits (95), Expect = 0.001
Identities = 55/219 (25%), Positives = 88/219 (40%), Gaps = 24/219 (10%)
Query: 80 LAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVS 133
LA+ LD ++ QL L+ C+LLASK +E + +E+L C+ + V
Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
Query: 134 PRQ-LRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATD 192
+Q L E+L+L +W+L A F+ + L D + L T
Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLH-----DGWPMICLEKTK 177
Query: 193 YTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTEL-------LAGITGTEVDCLRACQE 245
A Y A + ++Q AC S + L L +T D L C E
Sbjct: 178 LYMAKY-----ADYFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIE 232
Query: 246 QIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 284
++ A ++EA++ P++ + S Q SQ S P
Sbjct: 233 RLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 271
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 40.0 bits (92), Expect = 0.002
Identities = 57/223 (25%), Positives = 93/223 (41%), Gaps = 33/223 (14%)
Query: 80 LAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKL--RETTPLTIEKL----CIYTDHAVS 133
LA+ LD ++ QL L+ C+LLASK +E + +E+L C+ + V
Sbjct: 63 LAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVL 122
Query: 134 PRQ-LRDWEVLVLGKLKWDLAAVIAHDFLAFIL----HRLSLPRDRQALVKKHAQTFLAL 188
+Q L E+L+L +W+L A F+ + L H L + + + ++A
Sbjct: 123 TKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAK 182
Query: 189 CATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTEL-------LAGITGTEVDCLR 241
A DY + S+ AA AC S + L L +T D L
Sbjct: 183 YA-DYFLEV---------SLQAA-----ACVASSRIILRLSPTWPTRLHRLTAYSWDFLV 227
Query: 242 ACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGPSQTSTP 284
C E++ A ++EA++ P++ + S Q SQ S P
Sbjct: 228 QCIERLLIAHDNDVKEANKQRGQAGPQSAQLSVFQTASQPSRP 270
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 39.3 bits (90), Expect = 0.004
Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 17/152 (11%)
Query: 132 VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFIL--------HRL-----SLPRDRQALV 178
++ ++L E+L+L W+L FL + L H + PR + +
Sbjct: 170 LTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECL 229
Query: 179 KKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVD 238
K++A FL + D+ F + PS++A +GA+ C T L I+ ++
Sbjct: 230 KEYAHYFLEVTLQDHIFYKFQPSVVAAACVGAS----RICLQLSPYWTRDLQRISSYSLE 285
Query: 239 CLRACQEQIEAALRESLREASQTSSSPAPKAP 270
L C E + L++A S P
Sbjct: 286 HLSTCIEILLVVYDNVLKDAVAVKSQALAMVP 317
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,608,943
Number of Sequences: 37866
Number of extensions: 490970
Number of successful extensions: 2485
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2417
Number of HSP's gapped (non-prelim): 76
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.