Guide to the Human Genome
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Search of human proteins with 4502613

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502613 cyclin A [Homo sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502613 cyclin A [Homo sapiens]                                    863   0.0  
gi|161377472 cyclin A1 isoform c [Homo sapiens]                       348   4e-96
gi|161377470 cyclin A1 isoform c [Homo sapiens]                       348   4e-96
gi|161377468 cyclin A1 isoform b [Homo sapiens]                       348   4e-96
gi|4502611 cyclin A1 isoform a [Homo sapiens]                         348   4e-96
gi|14327896 cyclin B1 [Homo sapiens]                                  174   1e-43
gi|4757930 cyclin B2 [Homo sapiens]                                   155   7e-38
gi|90669307 cyclin B3 isoform 3 [Homo sapiens]                        142   6e-34
gi|118572588 cyclin F [Homo sapiens]                                  107   2e-23
gi|17318559 cyclin E1 isoform 1 [Homo sapiens]                        104   2e-22
gi|17318561 cyclin E1 isoform 2 [Homo sapiens]                        104   2e-22
gi|16306525 cyclin B3 isoform 1 [Homo sapiens]                        102   5e-22
gi|17318565 cyclin E2 [Homo sapiens]                                  100   3e-21
gi|153791755 cyclin domain containing [Homo sapiens]                   97   2e-20
gi|16950655 cyclin D1 [Homo sapiens]                                   97   4e-20
gi|4502619 cyclin D3 isoform 2 [Homo sapiens]                          95   1e-19
gi|4502617 cyclin D2 [Homo sapiens]                                    93   4e-19
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho...    82   7e-16
gi|197276674 cyclin J isoform 1 [Homo sapiens]                         71   2e-12
gi|209862835 cyclin D3 isoform 1 [Homo sapiens]                        69   8e-12
gi|40254889 cyclin J isoform 2 [Homo sapiens]                          68   2e-11
gi|197276676 cyclin J isoform 3 [Homo sapiens]                         67   4e-11
gi|40805832 cyclin G1 [Homo sapiens]                                   63   6e-10
gi|4757934 cyclin G1 [Homo sapiens]                                    63   6e-10
gi|94680985 cyclin J-like [Homo sapiens]                               52   1e-06
gi|4757936 cyclin G2 [Homo sapiens]                                    51   2e-06
gi|5802992 cyclin I [Homo sapiens]                                     50   4e-06
gi|89886237 cyclin I family, member 2 [Homo sapiens]                   49   9e-06
gi|42794779 myosin 18A isoform b [Homo sapiens]                        42   0.001
gi|28416946 myosin 18A isoform a [Homo sapiens]                        42   0.001

>gi|4502613 cyclin A [Homo sapiens]
          Length = 432

 Score =  863 bits (2231), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG 60
           MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG
Sbjct: 1   MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG 60

Query: 61  LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI 120
           LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI
Sbjct: 61  LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI 120

Query: 121 EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE 180
           EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE
Sbjct: 121 EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE 180

Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
           DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID
Sbjct: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240

Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK 300
           RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK
Sbjct: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK 300

Query: 301 VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF 360
           VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF
Sbjct: 301 VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF 360

Query: 361 HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG 420
           HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG
Sbjct: 361 HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG 420

Query: 421 VSLLNPPETLNL 432
           VSLLNPPETLNL
Sbjct: 421 VSLLNPPETLNL 432


>gi|161377472 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score =  348 bits (894), Expect = 4e-96
 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)

Query: 99  FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
           F I++DE E+  +   +  + +  ED    ++     G  K    L + +D +  SP  +
Sbjct: 91  FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 143

Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
           D S++ + E   S+      V +Y E+I+ YLRE E++ +PK  YMKKQPDIT  MR IL
Sbjct: 144 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 203

Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
           VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 204 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 263

Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
           V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL  PT NQFL QY L +Q    + E+LA 
Sbjct: 264 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 322

Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
           ++ ELSL++ADP+LKYLPS+IA AAF LA YTV    WPE+L   TGY+L  + PCL +L
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 382

Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
           H+ YL  P   QQ+IREKYK SKY  VSL+ PP  L L
Sbjct: 383 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420


>gi|161377470 cyclin A1 isoform c [Homo sapiens]
          Length = 421

 Score =  348 bits (894), Expect = 4e-96
 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)

Query: 99  FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
           F I++DE E+  +   +  + +  ED    ++     G  K    L + +D +  SP  +
Sbjct: 91  FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 143

Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
           D S++ + E   S+      V +Y E+I+ YLRE E++ +PK  YMKKQPDIT  MR IL
Sbjct: 144 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 203

Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
           VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 204 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 263

Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
           V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL  PT NQFL QY L +Q    + E+LA 
Sbjct: 264 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 322

Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
           ++ ELSL++ADP+LKYLPS+IA AAF LA YTV    WPE+L   TGY+L  + PCL +L
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 382

Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
           H+ YL  P   QQ+IREKYK SKY  VSL+ PP  L L
Sbjct: 383 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420


>gi|161377468 cyclin A1 isoform b [Homo sapiens]
          Length = 464

 Score =  348 bits (894), Expect = 4e-96
 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)

Query: 99  FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
           F I++DE E+  +   +  + +  ED    ++     G  K    L + +D +  SP  +
Sbjct: 134 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 186

Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
           D S++ + E   S+      V +Y E+I+ YLRE E++ +PK  YMKKQPDIT  MR IL
Sbjct: 187 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 246

Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
           VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 247 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 306

Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
           V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL  PT NQFL QY L +Q    + E+LA 
Sbjct: 307 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 365

Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
           ++ ELSL++ADP+LKYLPS+IA AAF LA YTV    WPE+L   TGY+L  + PCL +L
Sbjct: 366 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 425

Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
           H+ YL  P   QQ+IREKYK SKY  VSL+ PP  L L
Sbjct: 426 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 463


>gi|4502611 cyclin A1 isoform a [Homo sapiens]
          Length = 465

 Score =  348 bits (894), Expect = 4e-96
 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)

Query: 99  FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
           F I++DE E+  +   +  + +  ED    ++     G  K    L + +D +  SP  +
Sbjct: 135 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 187

Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
           D S++ + E   S+      V +Y E+I+ YLRE E++ +PK  YMKKQPDIT  MR IL
Sbjct: 188 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 247

Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
           VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 248 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 307

Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
           V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL  PT NQFL QY L +Q    + E+LA 
Sbjct: 308 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 366

Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
           ++ ELSL++ADP+LKYLPS+IA AAF LA YTV    WPE+L   TGY+L  + PCL +L
Sbjct: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 426

Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
           H+ YL  P   QQ+IREKYK SKY  VSL+ PP  L L
Sbjct: 427 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464


>gi|14327896 cyclin B1 [Homo sapiens]
          Length = 433

 Score =  174 bits (441), Expect = 1e-43
 Identities = 124/397 (31%), Positives = 201/397 (50%), Gaps = 16/397 (4%)

Query: 35  PEKAAPVQQPRTRAALAVLKSGNPRG-LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKAN 93
           P   A   +P  R   A+   GN      Q + P  +   P     V D+ +  P  K  
Sbjct: 28  PTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVP 87

Query: 94  SKQPA-FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSF 152
              P   +  V E E E + +P + +K+  E  L  ++A   P       P +  +  +F
Sbjct: 88  MLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILV-DTASPSPMETSGCAPAEEDLCQAF 146

Query: 153 ESPHTMDMSIVLED---EKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNS 209
                 D+ + + D   E     N   +Y +DI+ YLR++E +   +  Y+  + ++T +
Sbjct: 147 S-----DVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGN 200

Query: 210 MRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEE 269
           MRAIL+DWLV+V  +++L  ET+++ V+ IDRF+ +  V +  LQLVG  AM +ASK+EE
Sbjct: 201 MRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEE 260

Query: 270 IYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKV 329
           +YPPE+ +F ++TD+TYTK Q+ +ME  +L+ L F L  P    FL +     +  + + 
Sbjct: 261 MYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGE-VDVEQ 319

Query: 330 ESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKP 389
            +LA +L EL+++D D  + + PS IA  AF LAL  +    W  +L     YT ESL P
Sbjct: 320 HTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLP 378

Query: 390 CLMDLHQTYLKAPQ--HAQQSIREKYKNSKYHGVSLL 424
            +  L +  +   Q      +++ KY  SK+  +S L
Sbjct: 379 VMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTL 415


>gi|4757930 cyclin B2 [Homo sapiens]
          Length = 398

 Score =  155 bits (392), Expect = 7e-38
 Identities = 96/250 (38%), Positives = 145/250 (58%), Gaps = 5/250 (2%)

Query: 177 DYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAV 236
           DY +DI+ YLR++EV       ++  + DI   MRAILVDWLV+V  +++L  ETL++ V
Sbjct: 133 DYVKDIYQYLRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCV 191

Query: 237 NYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEH 296
             +DRFL    V R KLQLVG  A+LLASK+EE++ P + +FVYITD+ YT  Q+  ME 
Sbjct: 192 GIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMET 251

Query: 297 LVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIA 356
           L+LK L F+L  P    FL +     +  + +  +LA +L EL+LID D  + Y PS +A
Sbjct: 252 LILKELKFELGRPLPLHFLRRASKAGE-VDVEQHTLAKYLMELTLIDYD-MVHYHPSKVA 309

Query: 357 GAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQ--SIREKYK 414
            AA  L+   +    W       TGYT   +   +  + +  +K  ++  +  +I+ KY 
Sbjct: 310 AAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYA 369

Query: 415 NSKYHGVSLL 424
           +SK   +S++
Sbjct: 370 SSKLLKISMI 379


>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
          Length = 1395

 Score =  142 bits (358), Expect = 6e-34
 Identities = 93/270 (34%), Positives = 148/270 (54%), Gaps = 9/270 (3%)

Query: 165  EDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE 224
            ED    S N  P Y ++I +Y++E E +      YM +Q +IT+ MRAILVDWLVEV   
Sbjct: 1118 EDSSDPSFN--PMYAKEIFSYMKEREEQFI-LTDYMNRQIEITSDMRAILVDWLVEVQVS 1174

Query: 225  YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDD 284
            +++ +ETL+LAV  +D +L      + KLQL+G  A ++A+KFEE   P V +FVYI DD
Sbjct: 1175 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 1234

Query: 285  TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY--FLHQQPANCKVESLAMFLGELSLI 342
             Y + +VL ME  +L VL  D+  P    FL +Y   +H    N K  +L+ ++ E++L 
Sbjct: 1235 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIH---TNMKTLTLSRYICEMTLQ 1291

Query: 343  DADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAP 402
            +   Y++   S +A A+  LALY      W   L   +GY++  L P +  L++    + 
Sbjct: 1292 EYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSS 1350

Query: 403  QHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
              + +++  KY +  +  V+ +   + L L
Sbjct: 1351 YDSLKAVYYKYSHPVFFEVAKIPALDMLKL 1380


>gi|118572588 cyclin F [Homo sapiens]
          Length = 786

 Score =  107 bits (267), Expect = 2e-23
 Identities = 72/227 (31%), Positives = 120/227 (52%), Gaps = 9/227 (3%)

Query: 203 QPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAML 262
           Q  + ++MR IL+DWLVEV       +  LHL V  +DR+L    V R +LQL+G A M+
Sbjct: 302 QKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMV 361

Query: 263 LASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQ 322
           + ++F       + E V++TD+TY  + ++RM   ++  L   +  PTV  +  +  L  
Sbjct: 362 ICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDY-KEVLLTL 420

Query: 323 QPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYT-VTGQSWPESLIRKTG 381
            P   + + L  FL ELSL+       Y P+ +A AA  LA  T    Q W   L   TG
Sbjct: 421 VPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTG 479

Query: 382 YTLESLKPCLMDLHQT--YLKAPQHAQQ----SIREKYKNSKYHGVS 422
           ++ E L PC++ LH+   +  AP+  +Q    ++++++++ +Y  +S
Sbjct: 480 FSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEIS 526


>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
          Length = 410

 Score =  104 bits (259), Expect = 2e-22
 Identities = 64/207 (30%), Positives = 117/207 (56%), Gaps = 29/207 (14%)

Query: 184 TYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFL 243
           TYLR+          ++++ P +   MRAIL+DWL+EV E YKL  ET +LA ++ DR++
Sbjct: 126 TYLRDQH--------FLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYM 177

Query: 244 SSM-SVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302
           ++  +V++  LQL+G +++ +A+K EEIYPP++ +F Y+TD   +  ++L ME +++K L
Sbjct: 178 ATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKAL 237

Query: 303 TFDLAAPTVNQFLTQY------------FLHQQPANCKVESLAMFLGELSLIDADPYLKY 350
            + L+  T+  +L  Y             L Q P    ++   +   +L ++D D  L++
Sbjct: 238 KWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELL--DLCVLDVD-CLEF 294

Query: 351 LPSVIAGAA-FHLA----LYTVTGQSW 372
              ++A +A +H +    +  V+G  W
Sbjct: 295 PYGILAASALYHFSSSELMQKVSGYQW 321


>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
          Length = 395

 Score =  104 bits (259), Expect = 2e-22
 Identities = 64/207 (30%), Positives = 117/207 (56%), Gaps = 29/207 (14%)

Query: 184 TYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFL 243
           TYLR+          ++++ P +   MRAIL+DWL+EV E YKL  ET +LA ++ DR++
Sbjct: 111 TYLRDQH--------FLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYM 162

Query: 244 SSM-SVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302
           ++  +V++  LQL+G +++ +A+K EEIYPP++ +F Y+TD   +  ++L ME +++K L
Sbjct: 163 ATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKAL 222

Query: 303 TFDLAAPTVNQFLTQY------------FLHQQPANCKVESLAMFLGELSLIDADPYLKY 350
            + L+  T+  +L  Y             L Q P    ++   +   +L ++D D  L++
Sbjct: 223 KWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELL--DLCVLDVD-CLEF 279

Query: 351 LPSVIAGAA-FHLA----LYTVTGQSW 372
              ++A +A +H +    +  V+G  W
Sbjct: 280 PYGILAASALYHFSSSELMQKVSGYQW 306


>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
          Length = 291

 Score =  102 bits (255), Expect = 5e-22
 Identities = 66/210 (31%), Positives = 112/210 (53%), Gaps = 6/210 (2%)

Query: 225 YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDD 284
           +++ +ETL+LAV  +D +L      + KLQL+G  A ++A+KFEE   P V +FVYI DD
Sbjct: 71  FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130

Query: 285 TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY--FLHQQPANCKVESLAMFLGELSLI 342
            Y + +VL ME  +L VL  D+  P    FL +Y   +H    N K  +L+ ++ E++L 
Sbjct: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIH---TNMKTLTLSRYICEMTLQ 187

Query: 343 DADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAP 402
           +   Y++   S +A A+  LALY      W   L   +GY++  L P +  L++    + 
Sbjct: 188 EYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSS 246

Query: 403 QHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
             + +++  KY +  +  V+ +   + L L
Sbjct: 247 YDSLKAVYYKYSHPVFFEVAKIPALDMLKL 276


>gi|17318565 cyclin E2 [Homo sapiens]
          Length = 404

 Score =  100 bits (248), Expect = 3e-21
 Identities = 48/115 (41%), Positives = 76/115 (66%), Gaps = 1/115 (0%)

Query: 205 DITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF-LSSMSVLRGKLQLVGTAAMLL 263
           D+   MR+IL+DWL+EV E Y L  ET +LA ++ DRF L+   + +  LQL+G  ++ +
Sbjct: 136 DLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFI 195

Query: 264 ASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY 318
           ASK EEIY P++ EF Y+TD   +++ +LRME ++LK L ++L   T+  +L  +
Sbjct: 196 ASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250


>gi|153791755 cyclin domain containing [Homo sapiens]
          Length = 350

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 69/249 (27%), Positives = 116/249 (46%), Gaps = 37/249 (14%)

Query: 123 EDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHEDI 182
           E   A      LPGP +P+  LD                          +    DY +  
Sbjct: 72  ESPSAARGGSPLPGPAQPVAQLD--------------------------LQTFRDYGQSC 105

Query: 183 HTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF 242
           + + +  E    P+   + +QP +T   R  L+ WL+ V  ++ L  E+L L VN +DRF
Sbjct: 106 YAFRKAQESHFHPREA-LARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRF 164

Query: 243 LSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302
           L++  V     QL+G  ++L+A K  E++PP V + + +    ++++Q+  +E +VL  L
Sbjct: 165 LTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKL 224

Query: 303 TFDLAAPTVNQFLTQYFLH--------QQPANCKVESLAMFLGELSLIDADPYLKYLPSV 354
            F L APT++ FL ++F H        +     + ++LA  + ELSL D   +  Y PS+
Sbjct: 225 HFTLGAPTISFFL-EHFTHARVEAGQAEASEALEAQALARGVAELSLADY-AFTSYSPSL 282

Query: 355 IAGAAFHLA 363
           +A     LA
Sbjct: 283 LAICCLALA 291


>gi|16950655 cyclin D1 [Homo sapiens]
          Length = 295

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 53/136 (38%), Positives = 82/136 (60%), Gaps = 2/136 (1%)

Query: 190 EVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSV 248
           E  C P V Y K  Q ++  SMR I+  W++EV EE K + E   LA+NY+DRFLS   V
Sbjct: 35  EETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPV 94

Query: 249 LRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAA 308
            + +LQL+G   M +ASK +E  P    +    TD++   +++L+ME L++  L ++LAA
Sbjct: 95  KKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAA 154

Query: 309 PTVNQFLTQYFLHQQP 324
            T + F+ ++FL + P
Sbjct: 155 MTPHDFI-EHFLSKMP 169


>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
          Length = 292

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 73/232 (31%), Positives = 116/232 (50%), Gaps = 10/232 (4%)

Query: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244
           L  +E +  P+  Y +  Q +I   MR +L  W++EV EE + + E   LA+NY+DR+LS
Sbjct: 31  LLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLS 90

Query: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304
            +   + +LQL+G   MLLASK  E  P  + +    TD   + +Q+   E LVL  L +
Sbjct: 91  CVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKW 150

Query: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIA----G 357
           DLAA   + FL  + LH+       ++L     +  L+L   D  +  Y PS+IA    G
Sbjct: 151 DLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIG 209

Query: 358 AAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQS 408
           AA   L   +++G    E L   TG  ++ L+ C   +     ++ + A Q+
Sbjct: 210 AAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 261


>gi|4502617 cyclin D2 [Homo sapiens]
          Length = 289

 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 72/243 (29%), Positives = 120/243 (49%), Gaps = 14/243 (5%)

Query: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244
           L  +E +  P+  Y K  Q DI   MR ++  W++EV EE K + E   LA+NY+DRFL+
Sbjct: 30  LLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLA 89

Query: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304
            +   +  LQL+G   M LASK +E  P    +    TD++   +++L  E +VL  L +
Sbjct: 90  GVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKW 149

Query: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIAGAAFH 361
           +LAA T + F+ ++ L + P   +  SL     +  ++L   D  +  Y PS+IA  +  
Sbjct: 150 NLAAVTPHDFI-EHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVG 208

Query: 362 LAL---------YTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREK 412
            A+          ++T  +  E L + T   ++ LK C   +    L + Q  +Q  R+ 
Sbjct: 209 AAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDG 268

Query: 413 YKN 415
            K+
Sbjct: 269 SKS 271


>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 307

 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 58/160 (36%), Positives = 88/160 (55%), Gaps = 6/160 (3%)

Query: 206 ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLAS 265
           +T  MRA++VDWLV+V E   L  +TL+LAV+ +D +LS+  V   +LQL+G A + +A 
Sbjct: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162

Query: 266 KFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDL--AAPTVNQFLTQYFLHQQ 323
           K EE   PE A    ++ D++++ ++LR E  +L  L F L    P +   L        
Sbjct: 163 KMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSS 222

Query: 324 PANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLA 363
           P   +V  LA +  ELSL++A+    + P   A AA  LA
Sbjct: 223 P---QVMLLATYFLELSLLEAEA-AGWEPGRRAAAALSLA 258


>gi|197276674 cyclin J isoform 1 [Homo sapiens]
          Length = 383

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 74/264 (28%), Positives = 113/264 (42%), Gaps = 41/264 (15%)

Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
           DIH  LR  E+K      Y  + P +  S+R    D +  V   + L     HLAV  +D
Sbjct: 15  DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69

Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
            F+    +   +L LV  + +LLASKFEE     P++ +   +   T      TK+ +L 
Sbjct: 70  LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129

Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLG-------E 338
           ME L+L+   ++L  PT   F+  Y         LH       +E   +++        E
Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189

Query: 339 LSLIDADPYLKYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPC---LMDL 394
           +SL D   +L Y PS++A A    + +      +WP  L R T Y+ + L  C   L+  
Sbjct: 190 VSLQDY-AFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIA 248

Query: 395 HQTYLK---------APQHAQQSI 409
           H   +K          PQ AQ S+
Sbjct: 249 HDNDVKEANKQRGQAGPQSAQLSV 272


>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
          Length = 211

 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 56/181 (30%), Positives = 89/181 (49%), Gaps = 9/181 (4%)

Query: 236 VNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME 295
           +NY+DR+LS +   + +LQL+G   MLLASK  E  P  + +    TD   + +Q+   E
Sbjct: 1   MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60

Query: 296 HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLP 352
            LVL  L +DLAA   + FL  + LH+       ++L     +  L+L   D  +  Y P
Sbjct: 61  VLVLGKLKWDLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPP 119

Query: 353 SVIA----GAAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQ 407
           S+IA    GAA   L   +++G    E L   TG  ++ L+ C   +     ++ + A Q
Sbjct: 120 SMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQ 179

Query: 408 S 408
           +
Sbjct: 180 T 180


>gi|40254889 cyclin J isoform 2 [Homo sapiens]
          Length = 372

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 69/256 (26%), Positives = 106/256 (41%), Gaps = 36/256 (14%)

Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
           DIH  LR  E+K      Y  + P +  S+R    D +  V   + L     HLAV  +D
Sbjct: 15  DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69

Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
            F+    +   +L LV  + +LLASKFEE     P++ +   +   T      TK+ +L 
Sbjct: 70  LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129

Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLGELSLIDAD 345
           ME L+L+   ++L  PT   F+  Y         LH       +E   +++ +     AD
Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKY----AD 185

Query: 346 PYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPC---LMDLHQTYLK-- 400
            +L+    V A       +      +WP  L R T Y+ + L  C   L+  H   +K  
Sbjct: 186 YFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEA 245

Query: 401 -------APQHAQQSI 409
                   PQ AQ S+
Sbjct: 246 NKQRGQAGPQSAQLSV 261


>gi|197276676 cyclin J isoform 3 [Homo sapiens]
          Length = 371

 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 69/251 (27%), Positives = 103/251 (41%), Gaps = 27/251 (10%)

Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
           DIH  LR  E+K      Y  + P +  S+R    D +  V   + L     HLAV  +D
Sbjct: 15  DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69

Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
            F+    +   +L LV  + +LLASKFEE     P++ +   +   T      TK+ +L 
Sbjct: 70  LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129

Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPS 353
           ME L+L+   ++L  PT   F+  Y           +   M   E + +    Y  Y   
Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189

Query: 354 VIAGAAFHLALYTV---TGQSWPESLIRKTGYTLESLKPC---LMDLHQTYLK------- 400
           V   AA  +A   +      +WP  L R T Y+ + L  C   L+  H   +K       
Sbjct: 190 VSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRG 249

Query: 401 --APQHAQQSI 409
              PQ AQ S+
Sbjct: 250 QAGPQSAQLSV 260


>gi|40805832 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 9/143 (6%)

Query: 186 LREMEVKCKPKVGYMKKQPD-------ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNY 238
           L E E +C+PKV  ++           +T  +R   V  L+ + + +    ET  LAVN 
Sbjct: 20  LLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNL 79

Query: 239 IDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEH 296
           +DRFLS M V    L  VG +   LA K   EE   P   + + I+   +T   ++RME 
Sbjct: 80  LDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139

Query: 297 LVLKVLTFDLAAPTVNQFLTQYF 319
           +VL+ + + + A T  QFL  Y+
Sbjct: 140 IVLEKVCWKVKATTAFQFLQLYY 162


>gi|4757934 cyclin G1 [Homo sapiens]
          Length = 295

 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 9/143 (6%)

Query: 186 LREMEVKCKPKVGYMKKQPD-------ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNY 238
           L E E +C+PKV  ++           +T  +R   V  L+ + + +    ET  LAVN 
Sbjct: 20  LLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNL 79

Query: 239 IDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEH 296
           +DRFLS M V    L  VG +   LA K   EE   P   + + I+   +T   ++RME 
Sbjct: 80  LDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139

Query: 297 LVLKVLTFDLAAPTVNQFLTQYF 319
           +VL+ + + + A T  QFL  Y+
Sbjct: 140 IVLEKVCWKVKATTAFQFLQLYY 162


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 70/291 (24%), Positives = 106/291 (36%), Gaps = 79/291 (27%)

Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
           D+H  LRE E+K      +    P + +  R   VD L  +    +L     HLAV  +D
Sbjct: 14  DVHCTLREKELKLPT---FRAHSPLLKS--RRFFVDILTLLSSHCQLCPAARHLAVYLLD 68

Query: 241 RFLSSMSVLRGK-LQLVGTAAMLLASKFEEIYP--------------------------- 272
            F+   +V   K L  V  + +LLA+    + P                           
Sbjct: 69  HFMDRYNVTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSSNSPASAP 128

Query: 273 ------PEVAEFVYITDD----------------------TYTKKQVLRMEHLVLKVLTF 304
                 P+VAE     +D                      T TKK++L  E L+L+  ++
Sbjct: 129 HPPPTPPQVAETTGKFEDREDHVPKLEQINSTRILSSQNFTLTKKELLSTELLLLEAFSW 188

Query: 305 DLAAPTVNQFLTQYFL----------HQQPANCK------VESLAMFLGELSLIDADPYL 348
           +L  PT   FL  Y L          H  P  C       ++  A +  E++L D   + 
Sbjct: 189 NLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTLQD-HIFY 247

Query: 349 KYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTY 398
           K+ PSV+A A    + +       W   L R + Y+LE L  C+  L   Y
Sbjct: 248 KFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVY 298


>gi|4757936 cyclin G2 [Homo sapiens]
          Length = 344

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 10/146 (6%)

Query: 182 IHTYLREMEVKCKPK---VGYMKKQPDITNSM----RAILVDWLVEVGEEYKLQNETLHL 234
           ++ YL E E + +P+   +  ++  P+  N++    R   V+ L  +   +    ET  L
Sbjct: 21  LNVYL-EQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVL 79

Query: 235 AVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVL 292
           AVN +DRFL+ M V    L  +G  + LLA++   E+   P   + + I+    T   + 
Sbjct: 80  AVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIK 139

Query: 293 RMEHLVLKVLTFDLAAPTVNQFLTQY 318
           RME ++ + L ++L A T   FL  Y
Sbjct: 140 RMEKIISEKLHYELEATTALNFLHLY 165


>gi|5802992 cyclin I [Homo sapiens]
          Length = 377

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 4/125 (3%)

Query: 194 KPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKL 253
           K  V  M    +++ S R  ++ WL ++  ++ L  ET  LA + +DRFL+++      L
Sbjct: 28  KVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYL 87

Query: 254 QLVGTAAMLLASKFEEIYPPEVAEFVYITDDTY---TKKQVLRMEHLVLKVLTFDLAAPT 310
             +  +   LA+K  E     +     +  D++   +  ++LRME ++L  L +DL   T
Sbjct: 88  SCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTAT 146

Query: 311 VNQFL 315
              FL
Sbjct: 147 PLDFL 151


>gi|89886237 cyclin I family, member 2 [Homo sapiens]
          Length = 369

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 3/118 (2%)

Query: 201 KKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAA 260
           K Q +I ++   +++ WL+ +   +     T +LA+    R L S+ V    L      +
Sbjct: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199

Query: 261 MLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLT 316
           + LA+K   EE + P+V +F       Y+  ++LRME  +L  L +DL   T   FLT
Sbjct: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLT 257


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 54/253 (21%), Positives = 101/253 (39%), Gaps = 21/253 (8%)

Query: 27   QEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVT 86
            QE ++ +  E+    Q  R    L      + R L Q ++   R  A L+D  ++ E   
Sbjct: 1391 QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450

Query: 87   VPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDY 146
            V   +   KQ  F   + +A +EAQ++  + +K++RE  +    A SL   ++ L   D 
Sbjct: 1451 VRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSL---KQQLEEKDM 1507

Query: 147  PMDGSFESPHTMDMSI----VLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVG--YM 200
             + G  +   +++  +      E +   S+ +V     D+   +++ E +   + G   M
Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM 1567

Query: 201  KKQPDI-----------TNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVL 249
             +Q  +           T+S      D  VE   +   Q +   + V   + +     VL
Sbjct: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ-SCQKKLKQMEVQLEEEYEDKQKVL 1626

Query: 250  RGKLQLVGTAAML 262
            R K +L G  A L
Sbjct: 1627 REKRELEGKLATL 1639


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 54/253 (21%), Positives = 101/253 (39%), Gaps = 21/253 (8%)

Query: 27   QEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVT 86
            QE ++ +  E+    Q  R    L      + R L Q ++   R  A L+D  ++ E   
Sbjct: 1391 QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450

Query: 87   VPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDY 146
            V   +   KQ  F   + +A +EAQ++  + +K++RE  +    A SL   ++ L   D 
Sbjct: 1451 VRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSL---KQQLEEKDM 1507

Query: 147  PMDGSFESPHTMDMSI----VLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVG--YM 200
             + G  +   +++  +      E +   S+ +V     D+   +++ E +   + G   M
Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM 1567

Query: 201  KKQPDI-----------TNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVL 249
             +Q  +           T+S      D  VE   +   Q +   + V   + +     VL
Sbjct: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ-SCQKKLKQMEVQLEEEYEDKQKVL 1626

Query: 250  RGKLQLVGTAAML 262
            R K +L G  A L
Sbjct: 1627 REKRELEGKLATL 1639


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,182,840
Number of Sequences: 37866
Number of extensions: 771466
Number of successful extensions: 2573
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 2492
Number of HSP's gapped (non-prelim): 88
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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