BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4502613 cyclin A [Homo sapiens] (432 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4502613 cyclin A [Homo sapiens] 863 0.0 gi|161377472 cyclin A1 isoform c [Homo sapiens] 348 4e-96 gi|161377470 cyclin A1 isoform c [Homo sapiens] 348 4e-96 gi|161377468 cyclin A1 isoform b [Homo sapiens] 348 4e-96 gi|4502611 cyclin A1 isoform a [Homo sapiens] 348 4e-96 gi|14327896 cyclin B1 [Homo sapiens] 174 1e-43 gi|4757930 cyclin B2 [Homo sapiens] 155 7e-38 gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 142 6e-34 gi|118572588 cyclin F [Homo sapiens] 107 2e-23 gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 104 2e-22 gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 104 2e-22 gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 102 5e-22 gi|17318565 cyclin E2 [Homo sapiens] 100 3e-21 gi|153791755 cyclin domain containing [Homo sapiens] 97 2e-20 gi|16950655 cyclin D1 [Homo sapiens] 97 4e-20 gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 95 1e-19 gi|4502617 cyclin D2 [Homo sapiens] 93 4e-19 gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 82 7e-16 gi|197276674 cyclin J isoform 1 [Homo sapiens] 71 2e-12 gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 69 8e-12 gi|40254889 cyclin J isoform 2 [Homo sapiens] 68 2e-11 gi|197276676 cyclin J isoform 3 [Homo sapiens] 67 4e-11 gi|40805832 cyclin G1 [Homo sapiens] 63 6e-10 gi|4757934 cyclin G1 [Homo sapiens] 63 6e-10 gi|94680985 cyclin J-like [Homo sapiens] 52 1e-06 gi|4757936 cyclin G2 [Homo sapiens] 51 2e-06 gi|5802992 cyclin I [Homo sapiens] 50 4e-06 gi|89886237 cyclin I family, member 2 [Homo sapiens] 49 9e-06 gi|42794779 myosin 18A isoform b [Homo sapiens] 42 0.001 gi|28416946 myosin 18A isoform a [Homo sapiens] 42 0.001 >gi|4502613 cyclin A [Homo sapiens] Length = 432 Score = 863 bits (2231), Expect = 0.0 Identities = 432/432 (100%), Positives = 432/432 (100%) Query: 1 MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG 60 MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG Sbjct: 1 MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG 60 Query: 61 LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI 120 LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI Sbjct: 61 LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI 120 Query: 121 EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE 180 EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE Sbjct: 121 EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE 180 Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID Sbjct: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240 Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK 300 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK Sbjct: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK 300 Query: 301 VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF 360 VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF Sbjct: 301 VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF 360 Query: 361 HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG 420 HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG Sbjct: 361 HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG 420 Query: 421 VSLLNPPETLNL 432 VSLLNPPETLNL Sbjct: 421 VSLLNPPETLNL 432 >gi|161377472 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 348 bits (894), Expect = 4e-96 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%) Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158 F I++DE E+ + + + + ED ++ G K L + +D + SP + Sbjct: 91 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 143 Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214 D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL Sbjct: 144 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 203 Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274 VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE Sbjct: 204 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 263 Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334 V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA Sbjct: 264 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 322 Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394 ++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 382 Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432 H+ YL P QQ+IREKYK SKY VSL+ PP L L Sbjct: 383 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 >gi|161377470 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 348 bits (894), Expect = 4e-96 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%) Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158 F I++DE E+ + + + + ED ++ G K L + +D + SP + Sbjct: 91 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 143 Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214 D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL Sbjct: 144 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 203 Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274 VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE Sbjct: 204 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 263 Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334 V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA Sbjct: 264 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 322 Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394 ++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 382 Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432 H+ YL P QQ+IREKYK SKY VSL+ PP L L Sbjct: 383 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420 >gi|161377468 cyclin A1 isoform b [Homo sapiens] Length = 464 Score = 348 bits (894), Expect = 4e-96 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%) Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158 F I++DE E+ + + + + ED ++ G K L + +D + SP + Sbjct: 134 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 186 Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214 D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL Sbjct: 187 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 246 Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274 VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE Sbjct: 247 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 306 Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334 V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA Sbjct: 307 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 365 Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394 ++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L Sbjct: 366 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 425 Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432 H+ YL P QQ+IREKYK SKY VSL+ PP L L Sbjct: 426 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 463 >gi|4502611 cyclin A1 isoform a [Homo sapiens] Length = 465 Score = 348 bits (894), Expect = 4e-96 Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%) Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158 F I++DE E+ + + + + ED ++ G K L + +D + SP + Sbjct: 135 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 187 Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214 D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL Sbjct: 188 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 247 Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274 VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE Sbjct: 248 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 307 Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334 V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA Sbjct: 308 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 366 Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394 ++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L Sbjct: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 426 Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432 H+ YL P QQ+IREKYK SKY VSL+ PP L L Sbjct: 427 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464 >gi|14327896 cyclin B1 [Homo sapiens] Length = 433 Score = 174 bits (441), Expect = 1e-43 Identities = 124/397 (31%), Positives = 201/397 (50%), Gaps = 16/397 (4%) Query: 35 PEKAAPVQQPRTRAALAVLKSGNPRG-LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKAN 93 P A +P R A+ GN Q + P + P V D+ + P K Sbjct: 28 PTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVP 87 Query: 94 SKQPA-FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSF 152 P + V E E E + +P + +K+ E L ++A P P + + +F Sbjct: 88 MLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILV-DTASPSPMETSGCAPAEEDLCQAF 146 Query: 153 ESPHTMDMSIVLED---EKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNS 209 D+ + + D E N +Y +DI+ YLR++E + + Y+ + ++T + Sbjct: 147 S-----DVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGN 200 Query: 210 MRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEE 269 MRAIL+DWLV+V +++L ET+++ V+ IDRF+ + V + LQLVG AM +ASK+EE Sbjct: 201 MRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEE 260 Query: 270 IYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKV 329 +YPPE+ +F ++TD+TYTK Q+ +ME +L+ L F L P FL + + + + Sbjct: 261 MYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGE-VDVEQ 319 Query: 330 ESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKP 389 +LA +L EL+++D D + + PS IA AF LAL + W +L YT ESL P Sbjct: 320 HTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLP 378 Query: 390 CLMDLHQTYLKAPQ--HAQQSIREKYKNSKYHGVSLL 424 + L + + Q +++ KY SK+ +S L Sbjct: 379 VMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTL 415 >gi|4757930 cyclin B2 [Homo sapiens] Length = 398 Score = 155 bits (392), Expect = 7e-38 Identities = 96/250 (38%), Positives = 145/250 (58%), Gaps = 5/250 (2%) Query: 177 DYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAV 236 DY +DI+ YLR++EV ++ + DI MRAILVDWLV+V +++L ETL++ V Sbjct: 133 DYVKDIYQYLRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCV 191 Query: 237 NYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEH 296 +DRFL V R KLQLVG A+LLASK+EE++ P + +FVYITD+ YT Q+ ME Sbjct: 192 GIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMET 251 Query: 297 LVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIA 356 L+LK L F+L P FL + + + + +LA +L EL+LID D + Y PS +A Sbjct: 252 LILKELKFELGRPLPLHFLRRASKAGE-VDVEQHTLAKYLMELTLIDYD-MVHYHPSKVA 309 Query: 357 GAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQ--SIREKYK 414 AA L+ + W TGYT + + + + +K ++ + +I+ KY Sbjct: 310 AAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYA 369 Query: 415 NSKYHGVSLL 424 +SK +S++ Sbjct: 370 SSKLLKISMI 379 >gi|90669307 cyclin B3 isoform 3 [Homo sapiens] Length = 1395 Score = 142 bits (358), Expect = 6e-34 Identities = 93/270 (34%), Positives = 148/270 (54%), Gaps = 9/270 (3%) Query: 165 EDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE 224 ED S N P Y ++I +Y++E E + YM +Q +IT+ MRAILVDWLVEV Sbjct: 1118 EDSSDPSFN--PMYAKEIFSYMKEREEQFI-LTDYMNRQIEITSDMRAILVDWLVEVQVS 1174 Query: 225 YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDD 284 +++ +ETL+LAV +D +L + KLQL+G A ++A+KFEE P V +FVYI DD Sbjct: 1175 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 1234 Query: 285 TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY--FLHQQPANCKVESLAMFLGELSLI 342 Y + +VL ME +L VL D+ P FL +Y +H N K +L+ ++ E++L Sbjct: 1235 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIH---TNMKTLTLSRYICEMTLQ 1291 Query: 343 DADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAP 402 + Y++ S +A A+ LALY W L +GY++ L P + L++ + Sbjct: 1292 EYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSS 1350 Query: 403 QHAQQSIREKYKNSKYHGVSLLNPPETLNL 432 + +++ KY + + V+ + + L L Sbjct: 1351 YDSLKAVYYKYSHPVFFEVAKIPALDMLKL 1380 >gi|118572588 cyclin F [Homo sapiens] Length = 786 Score = 107 bits (267), Expect = 2e-23 Identities = 72/227 (31%), Positives = 120/227 (52%), Gaps = 9/227 (3%) Query: 203 QPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAML 262 Q + ++MR IL+DWLVEV + LHL V +DR+L V R +LQL+G A M+ Sbjct: 302 QKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMV 361 Query: 263 LASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQ 322 + ++F + E V++TD+TY + ++RM ++ L + PTV + + L Sbjct: 362 ICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDY-KEVLLTL 420 Query: 323 QPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYT-VTGQSWPESLIRKTG 381 P + + L FL ELSL+ Y P+ +A AA LA T Q W L TG Sbjct: 421 VPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTG 479 Query: 382 YTLESLKPCLMDLHQT--YLKAPQHAQQ----SIREKYKNSKYHGVS 422 ++ E L PC++ LH+ + AP+ +Q ++++++++ +Y +S Sbjct: 480 FSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEIS 526 >gi|17318559 cyclin E1 isoform 1 [Homo sapiens] Length = 410 Score = 104 bits (259), Expect = 2e-22 Identities = 64/207 (30%), Positives = 117/207 (56%), Gaps = 29/207 (14%) Query: 184 TYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFL 243 TYLR+ ++++ P + MRAIL+DWL+EV E YKL ET +LA ++ DR++ Sbjct: 126 TYLRDQH--------FLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYM 177 Query: 244 SSM-SVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302 ++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME +++K L Sbjct: 178 ATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKAL 237 Query: 303 TFDLAAPTVNQFLTQY------------FLHQQPANCKVESLAMFLGELSLIDADPYLKY 350 + L+ T+ +L Y L Q P ++ + +L ++D D L++ Sbjct: 238 KWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELL--DLCVLDVD-CLEF 294 Query: 351 LPSVIAGAA-FHLA----LYTVTGQSW 372 ++A +A +H + + V+G W Sbjct: 295 PYGILAASALYHFSSSELMQKVSGYQW 321 >gi|17318561 cyclin E1 isoform 2 [Homo sapiens] Length = 395 Score = 104 bits (259), Expect = 2e-22 Identities = 64/207 (30%), Positives = 117/207 (56%), Gaps = 29/207 (14%) Query: 184 TYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFL 243 TYLR+ ++++ P + MRAIL+DWL+EV E YKL ET +LA ++ DR++ Sbjct: 111 TYLRDQH--------FLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYM 162 Query: 244 SSM-SVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302 ++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME +++K L Sbjct: 163 ATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKAL 222 Query: 303 TFDLAAPTVNQFLTQY------------FLHQQPANCKVESLAMFLGELSLIDADPYLKY 350 + L+ T+ +L Y L Q P ++ + +L ++D D L++ Sbjct: 223 KWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELL--DLCVLDVD-CLEF 279 Query: 351 LPSVIAGAA-FHLA----LYTVTGQSW 372 ++A +A +H + + V+G W Sbjct: 280 PYGILAASALYHFSSSELMQKVSGYQW 306 >gi|16306525 cyclin B3 isoform 1 [Homo sapiens] Length = 291 Score = 102 bits (255), Expect = 5e-22 Identities = 66/210 (31%), Positives = 112/210 (53%), Gaps = 6/210 (2%) Query: 225 YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDD 284 +++ +ETL+LAV +D +L + KLQL+G A ++A+KFEE P V +FVYI DD Sbjct: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130 Query: 285 TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY--FLHQQPANCKVESLAMFLGELSLI 342 Y + +VL ME +L VL D+ P FL +Y +H N K +L+ ++ E++L Sbjct: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIH---TNMKTLTLSRYICEMTLQ 187 Query: 343 DADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAP 402 + Y++ S +A A+ LALY W L +GY++ L P + L++ + Sbjct: 188 EYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSS 246 Query: 403 QHAQQSIREKYKNSKYHGVSLLNPPETLNL 432 + +++ KY + + V+ + + L L Sbjct: 247 YDSLKAVYYKYSHPVFFEVAKIPALDMLKL 276 >gi|17318565 cyclin E2 [Homo sapiens] Length = 404 Score = 100 bits (248), Expect = 3e-21 Identities = 48/115 (41%), Positives = 76/115 (66%), Gaps = 1/115 (0%) Query: 205 DITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF-LSSMSVLRGKLQLVGTAAMLL 263 D+ MR+IL+DWL+EV E Y L ET +LA ++ DRF L+ + + LQL+G ++ + Sbjct: 136 DLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFI 195 Query: 264 ASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY 318 ASK EEIY P++ EF Y+TD +++ +LRME ++LK L ++L T+ +L + Sbjct: 196 ASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250 >gi|153791755 cyclin domain containing [Homo sapiens] Length = 350 Score = 97.4 bits (241), Expect = 2e-20 Identities = 69/249 (27%), Positives = 116/249 (46%), Gaps = 37/249 (14%) Query: 123 EDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHEDI 182 E A LPGP +P+ LD + DY + Sbjct: 72 ESPSAARGGSPLPGPAQPVAQLD--------------------------LQTFRDYGQSC 105 Query: 183 HTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF 242 + + + E P+ + +QP +T R L+ WL+ V ++ L E+L L VN +DRF Sbjct: 106 YAFRKAQESHFHPREA-LARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRF 164 Query: 243 LSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302 L++ V QL+G ++L+A K E++PP V + + + ++++Q+ +E +VL L Sbjct: 165 LTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKL 224 Query: 303 TFDLAAPTVNQFLTQYFLH--------QQPANCKVESLAMFLGELSLIDADPYLKYLPSV 354 F L APT++ FL ++F H + + ++LA + ELSL D + Y PS+ Sbjct: 225 HFTLGAPTISFFL-EHFTHARVEAGQAEASEALEAQALARGVAELSLADY-AFTSYSPSL 282 Query: 355 IAGAAFHLA 363 +A LA Sbjct: 283 LAICCLALA 291 >gi|16950655 cyclin D1 [Homo sapiens] Length = 295 Score = 96.7 bits (239), Expect = 4e-20 Identities = 53/136 (38%), Positives = 82/136 (60%), Gaps = 2/136 (1%) Query: 190 EVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSV 248 E C P V Y K Q ++ SMR I+ W++EV EE K + E LA+NY+DRFLS V Sbjct: 35 EETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPV 94 Query: 249 LRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAA 308 + +LQL+G M +ASK +E P + TD++ +++L+ME L++ L ++LAA Sbjct: 95 KKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAA 154 Query: 309 PTVNQFLTQYFLHQQP 324 T + F+ ++FL + P Sbjct: 155 MTPHDFI-EHFLSKMP 169 >gi|4502619 cyclin D3 isoform 2 [Homo sapiens] Length = 292 Score = 94.7 bits (234), Expect = 1e-19 Identities = 73/232 (31%), Positives = 116/232 (50%), Gaps = 10/232 (4%) Query: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244 L +E + P+ Y + Q +I MR +L W++EV EE + + E LA+NY+DR+LS Sbjct: 31 LLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLS 90 Query: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304 + + +LQL+G MLLASK E P + + TD + +Q+ E LVL L + Sbjct: 91 CVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKW 150 Query: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIA----G 357 DLAA + FL + LH+ ++L + L+L D + Y PS+IA G Sbjct: 151 DLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIG 209 Query: 358 AAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQS 408 AA L +++G E L TG ++ L+ C + ++ + A Q+ Sbjct: 210 AAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 261 >gi|4502617 cyclin D2 [Homo sapiens] Length = 289 Score = 93.2 bits (230), Expect = 4e-19 Identities = 72/243 (29%), Positives = 120/243 (49%), Gaps = 14/243 (5%) Query: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244 L +E + P+ Y K Q DI MR ++ W++EV EE K + E LA+NY+DRFL+ Sbjct: 30 LLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLA 89 Query: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304 + + LQL+G M LASK +E P + TD++ +++L E +VL L + Sbjct: 90 GVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKW 149 Query: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIAGAAFH 361 +LAA T + F+ ++ L + P + SL + ++L D + Y PS+IA + Sbjct: 150 NLAAVTPHDFI-EHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVG 208 Query: 362 LAL---------YTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREK 412 A+ ++T + E L + T ++ LK C + L + Q +Q R+ Sbjct: 209 AAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDG 268 Query: 413 YKN 415 K+ Sbjct: 269 SKS 271 >gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo sapiens] Length = 307 Score = 82.4 bits (202), Expect = 7e-16 Identities = 58/160 (36%), Positives = 88/160 (55%), Gaps = 6/160 (3%) Query: 206 ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLAS 265 +T MRA++VDWLV+V E L +TL+LAV+ +D +LS+ V +LQL+G A + +A Sbjct: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162 Query: 266 KFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDL--AAPTVNQFLTQYFLHQQ 323 K EE PE A ++ D++++ ++LR E +L L F L P + L Sbjct: 163 KMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSS 222 Query: 324 PANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLA 363 P +V LA + ELSL++A+ + P A AA LA Sbjct: 223 P---QVMLLATYFLELSLLEAEA-AGWEPGRRAAAALSLA 258 >gi|197276674 cyclin J isoform 1 [Homo sapiens] Length = 383 Score = 71.2 bits (173), Expect = 2e-12 Identities = 74/264 (28%), Positives = 113/264 (42%), Gaps = 41/264 (15%) Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240 DIH LR E+K Y + P + S+R D + V + L HLAV +D Sbjct: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69 Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293 F+ + +L LV + +LLASKFEE P++ + + T TK+ +L Sbjct: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129 Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLG-------E 338 ME L+L+ ++L PT F+ Y LH +E +++ E Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189 Query: 339 LSLIDADPYLKYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPC---LMDL 394 +SL D +L Y PS++A A + + +WP L R T Y+ + L C L+ Sbjct: 190 VSLQDY-AFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIA 248 Query: 395 HQTYLK---------APQHAQQSI 409 H +K PQ AQ S+ Sbjct: 249 HDNDVKEANKQRGQAGPQSAQLSV 272 >gi|209862835 cyclin D3 isoform 1 [Homo sapiens] Length = 211 Score = 68.9 bits (167), Expect = 8e-12 Identities = 56/181 (30%), Positives = 89/181 (49%), Gaps = 9/181 (4%) Query: 236 VNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME 295 +NY+DR+LS + + +LQL+G MLLASK E P + + TD + +Q+ E Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60 Query: 296 HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLP 352 LVL L +DLAA + FL + LH+ ++L + L+L D + Y P Sbjct: 61 VLVLGKLKWDLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPP 119 Query: 353 SVIA----GAAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQ 407 S+IA GAA L +++G E L TG ++ L+ C + ++ + A Q Sbjct: 120 SMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQ 179 Query: 408 S 408 + Sbjct: 180 T 180 >gi|40254889 cyclin J isoform 2 [Homo sapiens] Length = 372 Score = 67.8 bits (164), Expect = 2e-11 Identities = 69/256 (26%), Positives = 106/256 (41%), Gaps = 36/256 (14%) Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240 DIH LR E+K Y + P + S+R D + V + L HLAV +D Sbjct: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69 Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293 F+ + +L LV + +LLASKFEE P++ + + T TK+ +L Sbjct: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129 Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLGELSLIDAD 345 ME L+L+ ++L PT F+ Y LH +E +++ + AD Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKY----AD 185 Query: 346 PYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPC---LMDLHQTYLK-- 400 +L+ V A + +WP L R T Y+ + L C L+ H +K Sbjct: 186 YFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEA 245 Query: 401 -------APQHAQQSI 409 PQ AQ S+ Sbjct: 246 NKQRGQAGPQSAQLSV 261 >gi|197276676 cyclin J isoform 3 [Homo sapiens] Length = 371 Score = 66.6 bits (161), Expect = 4e-11 Identities = 69/251 (27%), Positives = 103/251 (41%), Gaps = 27/251 (10%) Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240 DIH LR E+K Y + P + S+R D + V + L HLAV +D Sbjct: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69 Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293 F+ + +L LV + +LLASKFEE P++ + + T TK+ +L Sbjct: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129 Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPS 353 ME L+L+ ++L PT F+ Y + M E + + Y Y Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189 Query: 354 VIAGAAFHLALYTV---TGQSWPESLIRKTGYTLESLKPC---LMDLHQTYLK------- 400 V AA +A + +WP L R T Y+ + L C L+ H +K Sbjct: 190 VSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRG 249 Query: 401 --APQHAQQSI 409 PQ AQ S+ Sbjct: 250 QAGPQSAQLSV 260 >gi|40805832 cyclin G1 [Homo sapiens] Length = 295 Score = 62.8 bits (151), Expect = 6e-10 Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 9/143 (6%) Query: 186 LREMEVKCKPKVGYMKKQPD-------ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNY 238 L E E +C+PKV ++ +T +R V L+ + + + ET LAVN Sbjct: 20 LLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNL 79 Query: 239 IDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEH 296 +DRFLS M V L VG + LA K EE P + + I+ +T ++RME Sbjct: 80 LDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139 Query: 297 LVLKVLTFDLAAPTVNQFLTQYF 319 +VL+ + + + A T QFL Y+ Sbjct: 140 IVLEKVCWKVKATTAFQFLQLYY 162 >gi|4757934 cyclin G1 [Homo sapiens] Length = 295 Score = 62.8 bits (151), Expect = 6e-10 Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 9/143 (6%) Query: 186 LREMEVKCKPKVGYMKKQPD-------ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNY 238 L E E +C+PKV ++ +T +R V L+ + + + ET LAVN Sbjct: 20 LLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNL 79 Query: 239 IDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEH 296 +DRFLS M V L VG + LA K EE P + + I+ +T ++RME Sbjct: 80 LDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139 Query: 297 LVLKVLTFDLAAPTVNQFLTQYF 319 +VL+ + + + A T QFL Y+ Sbjct: 140 IVLEKVCWKVKATTAFQFLQLYY 162 >gi|94680985 cyclin J-like [Homo sapiens] Length = 435 Score = 51.6 bits (122), Expect = 1e-06 Identities = 70/291 (24%), Positives = 106/291 (36%), Gaps = 79/291 (27%) Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240 D+H LRE E+K + P + + R VD L + +L HLAV +D Sbjct: 14 DVHCTLREKELKLPT---FRAHSPLLKS--RRFFVDILTLLSSHCQLCPAARHLAVYLLD 68 Query: 241 RFLSSMSVLRGK-LQLVGTAAMLLASKFEEIYP--------------------------- 272 F+ +V K L V + +LLA+ + P Sbjct: 69 HFMDRYNVTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSSNSPASAP 128 Query: 273 ------PEVAEFVYITDD----------------------TYTKKQVLRMEHLVLKVLTF 304 P+VAE +D T TKK++L E L+L+ ++ Sbjct: 129 HPPPTPPQVAETTGKFEDREDHVPKLEQINSTRILSSQNFTLTKKELLSTELLLLEAFSW 188 Query: 305 DLAAPTVNQFLTQYFL----------HQQPANCK------VESLAMFLGELSLIDADPYL 348 +L PT FL Y L H P C ++ A + E++L D + Sbjct: 189 NLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTLQD-HIFY 247 Query: 349 KYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTY 398 K+ PSV+A A + + W L R + Y+LE L C+ L Y Sbjct: 248 KFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVY 298 >gi|4757936 cyclin G2 [Homo sapiens] Length = 344 Score = 51.2 bits (121), Expect = 2e-06 Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 10/146 (6%) Query: 182 IHTYLREMEVKCKPK---VGYMKKQPDITNSM----RAILVDWLVEVGEEYKLQNETLHL 234 ++ YL E E + +P+ + ++ P+ N++ R V+ L + + ET L Sbjct: 21 LNVYL-EQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVL 79 Query: 235 AVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVL 292 AVN +DRFL+ M V L +G + LLA++ E+ P + + I+ T + Sbjct: 80 AVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIK 139 Query: 293 RMEHLVLKVLTFDLAAPTVNQFLTQY 318 RME ++ + L ++L A T FL Y Sbjct: 140 RMEKIISEKLHYELEATTALNFLHLY 165 >gi|5802992 cyclin I [Homo sapiens] Length = 377 Score = 50.1 bits (118), Expect = 4e-06 Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 4/125 (3%) Query: 194 KPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKL 253 K V M +++ S R ++ WL ++ ++ L ET LA + +DRFL+++ L Sbjct: 28 KVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYL 87 Query: 254 QLVGTAAMLLASKFEEIYPPEVAEFVYITDDTY---TKKQVLRMEHLVLKVLTFDLAAPT 310 + + LA+K E + + D++ + ++LRME ++L L +DL T Sbjct: 88 SCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTAT 146 Query: 311 VNQFL 315 FL Sbjct: 147 PLDFL 151 >gi|89886237 cyclin I family, member 2 [Homo sapiens] Length = 369 Score = 48.9 bits (115), Expect = 9e-06 Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 3/118 (2%) Query: 201 KKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAA 260 K Q +I ++ +++ WL+ + + T +LA+ R L S+ V L + Sbjct: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199 Query: 261 MLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLT 316 + LA+K EE + P+V +F Y+ ++LRME +L L +DL T FLT Sbjct: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLT 257 >gi|42794779 myosin 18A isoform b [Homo sapiens] Length = 2039 Score = 42.0 bits (97), Expect = 0.001 Identities = 54/253 (21%), Positives = 101/253 (39%), Gaps = 21/253 (8%) Query: 27 QEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVT 86 QE ++ + E+ Q R L + R L Q ++ R A L+D ++ E Sbjct: 1391 QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450 Query: 87 VPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDY 146 V + KQ F + +A +EAQ++ + +K++RE + A SL ++ L D Sbjct: 1451 VRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSL---KQQLEEKDM 1507 Query: 147 PMDGSFESPHTMDMSI----VLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVG--YM 200 + G + +++ + E + S+ +V D+ +++ E + + G M Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM 1567 Query: 201 KKQPDI-----------TNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVL 249 +Q + T+S D VE + Q + + V + + VL Sbjct: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ-SCQKKLKQMEVQLEEEYEDKQKVL 1626 Query: 250 RGKLQLVGTAAML 262 R K +L G A L Sbjct: 1627 REKRELEGKLATL 1639 >gi|28416946 myosin 18A isoform a [Homo sapiens] Length = 2054 Score = 42.0 bits (97), Expect = 0.001 Identities = 54/253 (21%), Positives = 101/253 (39%), Gaps = 21/253 (8%) Query: 27 QEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVT 86 QE ++ + E+ Q R L + R L Q ++ R A L+D ++ E Sbjct: 1391 QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450 Query: 87 VPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDY 146 V + KQ F + +A +EAQ++ + +K++RE + A SL ++ L D Sbjct: 1451 VRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSL---KQQLEEKDM 1507 Query: 147 PMDGSFESPHTMDMSI----VLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVG--YM 200 + G + +++ + E + S+ +V D+ +++ E + + G M Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM 1567 Query: 201 KKQPDI-----------TNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVL 249 +Q + T+S D VE + Q + + V + + VL Sbjct: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ-SCQKKLKQMEVQLEEEYEDKQKVL 1626 Query: 250 RGKLQLVGTAAML 262 R K +L G A L Sbjct: 1627 REKRELEGKLATL 1639 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.132 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,182,840 Number of Sequences: 37866 Number of extensions: 771466 Number of successful extensions: 2573 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 2492 Number of HSP's gapped (non-prelim): 88 length of query: 432 length of database: 18,247,518 effective HSP length: 105 effective length of query: 327 effective length of database: 14,271,588 effective search space: 4666809276 effective search space used: 4666809276 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.