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Search of human proteins with 4502613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502613 cyclin A [Homo sapiens]
(432 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502613 cyclin A [Homo sapiens] 863 0.0
gi|161377472 cyclin A1 isoform c [Homo sapiens] 348 4e-96
gi|161377470 cyclin A1 isoform c [Homo sapiens] 348 4e-96
gi|161377468 cyclin A1 isoform b [Homo sapiens] 348 4e-96
gi|4502611 cyclin A1 isoform a [Homo sapiens] 348 4e-96
gi|14327896 cyclin B1 [Homo sapiens] 174 1e-43
gi|4757930 cyclin B2 [Homo sapiens] 155 7e-38
gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 142 6e-34
gi|118572588 cyclin F [Homo sapiens] 107 2e-23
gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 104 2e-22
gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 104 2e-22
gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 102 5e-22
gi|17318565 cyclin E2 [Homo sapiens] 100 3e-21
gi|153791755 cyclin domain containing [Homo sapiens] 97 2e-20
gi|16950655 cyclin D1 [Homo sapiens] 97 4e-20
gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 95 1e-19
gi|4502617 cyclin D2 [Homo sapiens] 93 4e-19
gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 82 7e-16
gi|197276674 cyclin J isoform 1 [Homo sapiens] 71 2e-12
gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 69 8e-12
gi|40254889 cyclin J isoform 2 [Homo sapiens] 68 2e-11
gi|197276676 cyclin J isoform 3 [Homo sapiens] 67 4e-11
gi|40805832 cyclin G1 [Homo sapiens] 63 6e-10
gi|4757934 cyclin G1 [Homo sapiens] 63 6e-10
gi|94680985 cyclin J-like [Homo sapiens] 52 1e-06
gi|4757936 cyclin G2 [Homo sapiens] 51 2e-06
gi|5802992 cyclin I [Homo sapiens] 50 4e-06
gi|89886237 cyclin I family, member 2 [Homo sapiens] 49 9e-06
gi|42794779 myosin 18A isoform b [Homo sapiens] 42 0.001
gi|28416946 myosin 18A isoform a [Homo sapiens] 42 0.001
>gi|4502613 cyclin A [Homo sapiens]
Length = 432
Score = 863 bits (2231), Expect = 0.0
Identities = 432/432 (100%), Positives = 432/432 (100%)
Query: 1 MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG 60
MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG
Sbjct: 1 MLGNSAPGPATREAGSALLALQQTALQEDQENINPEKAAPVQQPRTRAALAVLKSGNPRG 60
Query: 61 LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI 120
LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI
Sbjct: 61 LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKI 120
Query: 121 EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE 180
EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE
Sbjct: 121 EREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHE 180
Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID
Sbjct: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK 300
RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK
Sbjct: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLK 300
Query: 301 VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF 360
VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF
Sbjct: 301 VLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAF 360
Query: 361 HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG 420
HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG
Sbjct: 361 HLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREKYKNSKYHG 420
Query: 421 VSLLNPPETLNL 432
VSLLNPPETLNL
Sbjct: 421 VSLLNPPETLNL 432
>gi|161377472 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 348 bits (894), Expect = 4e-96
Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)
Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
F I++DE E+ + + + + ED ++ G K L + +D + SP +
Sbjct: 91 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 143
Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL
Sbjct: 144 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 203
Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 204 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 263
Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA
Sbjct: 264 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 322
Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 382
Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
H+ YL P QQ+IREKYK SKY VSL+ PP L L
Sbjct: 383 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420
>gi|161377470 cyclin A1 isoform c [Homo sapiens]
Length = 421
Score = 348 bits (894), Expect = 4e-96
Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)
Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
F I++DE E+ + + + + ED ++ G K L + +D + SP +
Sbjct: 91 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 143
Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL
Sbjct: 144 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 203
Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 204 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 263
Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA
Sbjct: 264 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 322
Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L
Sbjct: 323 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 382
Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
H+ YL P QQ+IREKYK SKY VSL+ PP L L
Sbjct: 383 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 420
>gi|161377468 cyclin A1 isoform b [Homo sapiens]
Length = 464
Score = 348 bits (894), Expect = 4e-96
Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)
Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
F I++DE E+ + + + + ED ++ G K L + +D + SP +
Sbjct: 134 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 186
Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL
Sbjct: 187 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 246
Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 247 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 306
Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA
Sbjct: 307 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 365
Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L
Sbjct: 366 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 425
Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
H+ YL P QQ+IREKYK SKY VSL+ PP L L
Sbjct: 426 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 463
>gi|4502611 cyclin A1 isoform a [Homo sapiens]
Length = 465
Score = 348 bits (894), Expect = 4e-96
Identities = 190/338 (56%), Positives = 238/338 (70%), Gaps = 12/338 (3%)
Query: 99 FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTM 158
F I++DE E+ + + + + ED ++ G K L + +D + SP +
Sbjct: 135 FDIYMDELEQGDRDSCSVREGMAFEDVYEVDT-----GTLKS--DLHFLLDFNTVSPMLV 187
Query: 159 DMSIVLEDEKPVSVN----EVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAIL 214
D S++ + E S+ V +Y E+I+ YLRE E++ +PK YMKKQPDIT MR IL
Sbjct: 188 DSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTIL 247
Query: 215 VDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPE 274
VDWLVEVGEEYKL+ ETL+LAVN++DRFLS MSVLRGKLQLVGTAAMLLASK+EEIYPPE
Sbjct: 248 VDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPE 307
Query: 275 VAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAM 334
V EFVYITDDTYTK+Q+L+MEHL+LKVL FDL PT NQFL QY L +Q + E+LA
Sbjct: 308 VDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQY-LRRQGVCVRTENLAK 366
Query: 335 FLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDL 394
++ ELSL++ADP+LKYLPS+IA AAF LA YTV WPE+L TGY+L + PCL +L
Sbjct: 367 YVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSEL 426
Query: 395 HQTYLKAPQHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
H+ YL P QQ+IREKYK SKY VSL+ PP L L
Sbjct: 427 HKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLL 464
>gi|14327896 cyclin B1 [Homo sapiens]
Length = 433
Score = 174 bits (441), Expect = 1e-43
Identities = 124/397 (31%), Positives = 201/397 (50%), Gaps = 16/397 (4%)
Query: 35 PEKAAPVQQPRTRAALAVLKSGNPRG-LAQQQRPKTRRVAPLKDLPVNDEHVTVPPWKAN 93
P A +P R A+ GN Q + P + P V D+ + P K
Sbjct: 28 PTAPAATSKPGLRPRTALGDIGNKVSEQLQAKMPMKKEAKPSATGKVIDKKLPKPLEKVP 87
Query: 94 SKQPA-FTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDYPMDGSF 152
P + V E E E + +P + +K+ E L ++A P P + + +F
Sbjct: 88 MLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILV-DTASPSPMETSGCAPAEEDLCQAF 146
Query: 153 ESPHTMDMSIVLED---EKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNS 209
D+ + + D E N +Y +DI+ YLR++E + + Y+ + ++T +
Sbjct: 147 S-----DVILAVNDVDAEDGADPNLCSEYVKDIYAYLRQLEEEQAVRPKYLLGR-EVTGN 200
Query: 210 MRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEE 269
MRAIL+DWLV+V +++L ET+++ V+ IDRF+ + V + LQLVG AM +ASK+EE
Sbjct: 201 MRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKKMLQLVGVTAMFIASKYEE 260
Query: 270 IYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKV 329
+YPPE+ +F ++TD+TYTK Q+ +ME +L+ L F L P FL + + + +
Sbjct: 261 MYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLPLHFLRRASKIGE-VDVEQ 319
Query: 330 ESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKP 389
+LA +L EL+++D D + + PS IA AF LAL + W +L YT ESL P
Sbjct: 320 HTLAKYLMELTMLDYD-MVHFPPSQIAAGAFCLALKILDNGEWTPTLQHYLSYTEESLLP 378
Query: 390 CLMDLHQTYLKAPQ--HAQQSIREKYKNSKYHGVSLL 424
+ L + + Q +++ KY SK+ +S L
Sbjct: 379 VMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTL 415
>gi|4757930 cyclin B2 [Homo sapiens]
Length = 398
Score = 155 bits (392), Expect = 7e-38
Identities = 96/250 (38%), Positives = 145/250 (58%), Gaps = 5/250 (2%)
Query: 177 DYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAV 236
DY +DI+ YLR++EV ++ + DI MRAILVDWLV+V +++L ETL++ V
Sbjct: 133 DYVKDIYQYLRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCV 191
Query: 237 NYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEH 296
+DRFL V R KLQLVG A+LLASK+EE++ P + +FVYITD+ YT Q+ ME
Sbjct: 192 GIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMET 251
Query: 297 LVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPSVIA 356
L+LK L F+L P FL + + + + +LA +L EL+LID D + Y PS +A
Sbjct: 252 LILKELKFELGRPLPLHFLRRASKAGE-VDVEQHTLAKYLMELTLIDYD-MVHYHPSKVA 309
Query: 357 GAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQ--SIREKYK 414
AA L+ + W TGYT + + + + +K ++ + +I+ KY
Sbjct: 310 AAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYA 369
Query: 415 NSKYHGVSLL 424
+SK +S++
Sbjct: 370 SSKLLKISMI 379
>gi|90669307 cyclin B3 isoform 3 [Homo sapiens]
Length = 1395
Score = 142 bits (358), Expect = 6e-34
Identities = 93/270 (34%), Positives = 148/270 (54%), Gaps = 9/270 (3%)
Query: 165 EDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEE 224
ED S N P Y ++I +Y++E E + YM +Q +IT+ MRAILVDWLVEV
Sbjct: 1118 EDSSDPSFN--PMYAKEIFSYMKEREEQFI-LTDYMNRQIEITSDMRAILVDWLVEVQVS 1174
Query: 225 YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDD 284
+++ +ETL+LAV +D +L + KLQL+G A ++A+KFEE P V +FVYI DD
Sbjct: 1175 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 1234
Query: 285 TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY--FLHQQPANCKVESLAMFLGELSLI 342
Y + +VL ME +L VL D+ P FL +Y +H N K +L+ ++ E++L
Sbjct: 1235 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIH---TNMKTLTLSRYICEMTLQ 1291
Query: 343 DADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAP 402
+ Y++ S +A A+ LALY W L +GY++ L P + L++ +
Sbjct: 1292 EYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSS 1350
Query: 403 QHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
+ +++ KY + + V+ + + L L
Sbjct: 1351 YDSLKAVYYKYSHPVFFEVAKIPALDMLKL 1380
>gi|118572588 cyclin F [Homo sapiens]
Length = 786
Score = 107 bits (267), Expect = 2e-23
Identities = 72/227 (31%), Positives = 120/227 (52%), Gaps = 9/227 (3%)
Query: 203 QPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAML 262
Q + ++MR IL+DWLVEV + LHL V +DR+L V R +LQL+G A M+
Sbjct: 302 QKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACMV 361
Query: 263 LASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQ 322
+ ++F + E V++TD+TY + ++RM ++ L + PTV + + L
Sbjct: 362 ICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDY-KEVLLTL 420
Query: 323 QPANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLALYT-VTGQSWPESLIRKTG 381
P + + L FL ELSL+ Y P+ +A AA LA T Q W L TG
Sbjct: 421 VPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTG 479
Query: 382 YTLESLKPCLMDLHQT--YLKAPQHAQQ----SIREKYKNSKYHGVS 422
++ E L PC++ LH+ + AP+ +Q ++++++++ +Y +S
Sbjct: 480 FSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEIS 526
>gi|17318559 cyclin E1 isoform 1 [Homo sapiens]
Length = 410
Score = 104 bits (259), Expect = 2e-22
Identities = 64/207 (30%), Positives = 117/207 (56%), Gaps = 29/207 (14%)
Query: 184 TYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFL 243
TYLR+ ++++ P + MRAIL+DWL+EV E YKL ET +LA ++ DR++
Sbjct: 126 TYLRDQH--------FLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYM 177
Query: 244 SSM-SVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302
++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME +++K L
Sbjct: 178 ATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKAL 237
Query: 303 TFDLAAPTVNQFLTQY------------FLHQQPANCKVESLAMFLGELSLIDADPYLKY 350
+ L+ T+ +L Y L Q P ++ + +L ++D D L++
Sbjct: 238 KWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELL--DLCVLDVD-CLEF 294
Query: 351 LPSVIAGAA-FHLA----LYTVTGQSW 372
++A +A +H + + V+G W
Sbjct: 295 PYGILAASALYHFSSSELMQKVSGYQW 321
>gi|17318561 cyclin E1 isoform 2 [Homo sapiens]
Length = 395
Score = 104 bits (259), Expect = 2e-22
Identities = 64/207 (30%), Positives = 117/207 (56%), Gaps = 29/207 (14%)
Query: 184 TYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFL 243
TYLR+ ++++ P + MRAIL+DWL+EV E YKL ET +LA ++ DR++
Sbjct: 111 TYLRDQH--------FLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYM 162
Query: 244 SSM-SVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302
++ +V++ LQL+G +++ +A+K EEIYPP++ +F Y+TD + ++L ME +++K L
Sbjct: 163 ATQENVVKTLLQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKAL 222
Query: 303 TFDLAAPTVNQFLTQY------------FLHQQPANCKVESLAMFLGELSLIDADPYLKY 350
+ L+ T+ +L Y L Q P ++ + +L ++D D L++
Sbjct: 223 KWRLSPLTIVSWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELL--DLCVLDVD-CLEF 279
Query: 351 LPSVIAGAA-FHLA----LYTVTGQSW 372
++A +A +H + + V+G W
Sbjct: 280 PYGILAASALYHFSSSELMQKVSGYQW 306
>gi|16306525 cyclin B3 isoform 1 [Homo sapiens]
Length = 291
Score = 102 bits (255), Expect = 5e-22
Identities = 66/210 (31%), Positives = 112/210 (53%), Gaps = 6/210 (2%)
Query: 225 YKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDD 284
+++ +ETL+LAV +D +L + KLQL+G A ++A+KFEE P V +FVYI DD
Sbjct: 71 FEMTHETLYLAVKLVDLYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDD 130
Query: 285 TYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY--FLHQQPANCKVESLAMFLGELSLI 342
Y + +VL ME +L VL D+ P FL +Y +H N K +L+ ++ E++L
Sbjct: 131 NYQRSEVLSMEINILNVLKCDINIPIAYHFLRRYARCIH---TNMKTLTLSRYICEMTLQ 187
Query: 343 DADPYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAP 402
+ Y++ S +A A+ LALY W L +GY++ L P + L++ +
Sbjct: 188 EYH-YVQEKASKLAAASLLLALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSS 246
Query: 403 QHAQQSIREKYKNSKYHGVSLLNPPETLNL 432
+ +++ KY + + V+ + + L L
Sbjct: 247 YDSLKAVYYKYSHPVFFEVAKIPALDMLKL 276
>gi|17318565 cyclin E2 [Homo sapiens]
Length = 404
Score = 100 bits (248), Expect = 3e-21
Identities = 48/115 (41%), Positives = 76/115 (66%), Gaps = 1/115 (0%)
Query: 205 DITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF-LSSMSVLRGKLQLVGTAAMLL 263
D+ MR+IL+DWL+EV E Y L ET +LA ++ DRF L+ + + LQL+G ++ +
Sbjct: 136 DLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFI 195
Query: 264 ASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY 318
ASK EEIY P++ EF Y+TD +++ +LRME ++LK L ++L T+ +L +
Sbjct: 196 ASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250
>gi|153791755 cyclin domain containing [Homo sapiens]
Length = 350
Score = 97.4 bits (241), Expect = 2e-20
Identities = 69/249 (27%), Positives = 116/249 (46%), Gaps = 37/249 (14%)
Query: 123 EDALAFNSAISLPGPRKPLVPLDYPMDGSFESPHTMDMSIVLEDEKPVSVNEVPDYHEDI 182
E A LPGP +P+ LD + DY +
Sbjct: 72 ESPSAARGGSPLPGPAQPVAQLD--------------------------LQTFRDYGQSC 105
Query: 183 HTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF 242
+ + + E P+ + +QP +T R L+ WL+ V ++ L E+L L VN +DRF
Sbjct: 106 YAFRKAQESHFHPREA-LARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRF 164
Query: 243 LSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVL 302
L++ V QL+G ++L+A K E++PP V + + + ++++Q+ +E +VL L
Sbjct: 165 LTTTPVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKL 224
Query: 303 TFDLAAPTVNQFLTQYFLH--------QQPANCKVESLAMFLGELSLIDADPYLKYLPSV 354
F L APT++ FL ++F H + + ++LA + ELSL D + Y PS+
Sbjct: 225 HFTLGAPTISFFL-EHFTHARVEAGQAEASEALEAQALARGVAELSLADY-AFTSYSPSL 282
Query: 355 IAGAAFHLA 363
+A LA
Sbjct: 283 LAICCLALA 291
>gi|16950655 cyclin D1 [Homo sapiens]
Length = 295
Score = 96.7 bits (239), Expect = 4e-20
Identities = 53/136 (38%), Positives = 82/136 (60%), Gaps = 2/136 (1%)
Query: 190 EVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSV 248
E C P V Y K Q ++ SMR I+ W++EV EE K + E LA+NY+DRFLS V
Sbjct: 35 EETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPV 94
Query: 249 LRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAA 308
+ +LQL+G M +ASK +E P + TD++ +++L+ME L++ L ++LAA
Sbjct: 95 KKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAA 154
Query: 309 PTVNQFLTQYFLHQQP 324
T + F+ ++FL + P
Sbjct: 155 MTPHDFI-EHFLSKMP 169
>gi|4502619 cyclin D3 isoform 2 [Homo sapiens]
Length = 292
Score = 94.7 bits (234), Expect = 1e-19
Identities = 73/232 (31%), Positives = 116/232 (50%), Gaps = 10/232 (4%)
Query: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244
L +E + P+ Y + Q +I MR +L W++EV EE + + E LA+NY+DR+LS
Sbjct: 31 LLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQRCEEEVFPLAMNYLDRYLS 90
Query: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304
+ + +LQL+G MLLASK E P + + TD + +Q+ E LVL L +
Sbjct: 91 CVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKW 150
Query: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIA----G 357
DLAA + FL + LH+ ++L + L+L D + Y PS+IA G
Sbjct: 151 DLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIG 209
Query: 358 AAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQS 408
AA L +++G E L TG ++ L+ C + ++ + A Q+
Sbjct: 210 AAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQT 261
>gi|4502617 cyclin D2 [Homo sapiens]
Length = 289
Score = 93.2 bits (230), Expect = 4e-19
Identities = 72/243 (29%), Positives = 120/243 (49%), Gaps = 14/243 (5%)
Query: 186 LREMEVKCKPKVGYMK-KQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLS 244
L +E + P+ Y K Q DI MR ++ W++EV EE K + E LA+NY+DRFL+
Sbjct: 30 LLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLA 89
Query: 245 SMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTF 304
+ + LQL+G M LASK +E P + TD++ +++L E +VL L +
Sbjct: 90 GVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKW 149
Query: 305 DLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLPSVIAGAAFH 361
+LAA T + F+ ++ L + P + SL + ++L D + Y PS+IA +
Sbjct: 150 NLAAVTPHDFI-EHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVG 208
Query: 362 LAL---------YTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQSIREK 412
A+ ++T + E L + T ++ LK C + L + Q +Q R+
Sbjct: 209 AAICGLQQDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDG 268
Query: 413 YKN 415
K+
Sbjct: 269 SKS 271
>gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo
sapiens]
Length = 307
Score = 82.4 bits (202), Expect = 7e-16
Identities = 58/160 (36%), Positives = 88/160 (55%), Gaps = 6/160 (3%)
Query: 206 ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLAS 265
+T MRA++VDWLV+V E L +TL+LAV+ +D +LS+ V +LQL+G A + +A
Sbjct: 103 VTPEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGRVRLHRLQLLGVACLFVAC 162
Query: 266 KFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDL--AAPTVNQFLTQYFLHQQ 323
K EE PE A ++ D++++ ++LR E +L L F L P + L
Sbjct: 163 KMEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRLHHPGPLLCLGLLAALAGSS 222
Query: 324 PANCKVESLAMFLGELSLIDADPYLKYLPSVIAGAAFHLA 363
P +V LA + ELSL++A+ + P A AA LA
Sbjct: 223 P---QVMLLATYFLELSLLEAEA-AGWEPGRRAAAALSLA 258
>gi|197276674 cyclin J isoform 1 [Homo sapiens]
Length = 383
Score = 71.2 bits (173), Expect = 2e-12
Identities = 74/264 (28%), Positives = 113/264 (42%), Gaps = 41/264 (15%)
Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
DIH LR E+K Y + P + S+R D + V + L HLAV +D
Sbjct: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69
Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
F+ + +L LV + +LLASKFEE P++ + + T TK+ +L
Sbjct: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129
Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLG-------E 338
ME L+L+ ++L PT F+ Y LH +E +++ E
Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189
Query: 339 LSLIDADPYLKYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPC---LMDL 394
+SL D +L Y PS++A A + + +WP L R T Y+ + L C L+
Sbjct: 190 VSLQDY-AFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIA 248
Query: 395 HQTYLK---------APQHAQQSI 409
H +K PQ AQ S+
Sbjct: 249 HDNDVKEANKQRGQAGPQSAQLSV 272
>gi|209862835 cyclin D3 isoform 1 [Homo sapiens]
Length = 211
Score = 68.9 bits (167), Expect = 8e-12
Identities = 56/181 (30%), Positives = 89/181 (49%), Gaps = 9/181 (4%)
Query: 236 VNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLRME 295
+NY+DR+LS + + +LQL+G MLLASK E P + + TD + +Q+ E
Sbjct: 1 MNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60
Query: 296 HLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGE--LSLIDAD-PYLKYLP 352
LVL L +DLAA + FL + LH+ ++L + L+L D + Y P
Sbjct: 61 VLVLGKLKWDLAAVIAHDFLA-FILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPP 119
Query: 353 SVIA----GAAFH-LALYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTYLKAPQHAQQ 407
S+IA GAA L +++G E L TG ++ L+ C + ++ + A Q
Sbjct: 120 SMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQ 179
Query: 408 S 408
+
Sbjct: 180 T 180
>gi|40254889 cyclin J isoform 2 [Homo sapiens]
Length = 372
Score = 67.8 bits (164), Expect = 2e-11
Identities = 69/256 (26%), Positives = 106/256 (41%), Gaps = 36/256 (14%)
Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
DIH LR E+K Y + P + S+R D + V + L HLAV +D
Sbjct: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69
Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
F+ + +L LV + +LLASKFEE P++ + + T TK+ +L
Sbjct: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129
Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYF--------LHQQPANCKVESLAMFLGELSLIDAD 345
ME L+L+ ++L PT F+ Y LH +E +++ + AD
Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKY----AD 185
Query: 346 PYLKYLPSVIAGAAFHLALYTVTGQSWPESLIRKTGYTLESLKPC---LMDLHQTYLK-- 400
+L+ V A + +WP L R T Y+ + L C L+ H +K
Sbjct: 186 YFLEVSLQVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEA 245
Query: 401 -------APQHAQQSI 409
PQ AQ S+
Sbjct: 246 NKQRGQAGPQSAQLSV 261
>gi|197276676 cyclin J isoform 3 [Homo sapiens]
Length = 371
Score = 66.6 bits (161), Expect = 4e-11
Identities = 69/251 (27%), Positives = 103/251 (41%), Gaps = 27/251 (10%)
Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
DIH LR E+K Y + P + S+R D + V + L HLAV +D
Sbjct: 15 DIHQALRYKELKLP---SYKGQSPQL--SLRRYFADLIAIVSNRFTLCPSARHLAVYLLD 69
Query: 241 RFLSSMSVLRGKLQLVGTAAMLLASKFEEIYP--PEVAEFVYITDDT-----YTKKQVLR 293
F+ + +L LV + +LLASKFEE P++ + + T TK+ +L
Sbjct: 70 LFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLH 129
Query: 294 MEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKYLPS 353
ME L+L+ ++L PT F+ Y + M E + + Y Y
Sbjct: 130 MELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMICLEKTKLYMAKYADYFLE 189
Query: 354 VIAGAAFHLALYTV---TGQSWPESLIRKTGYTLESLKPC---LMDLHQTYLK------- 400
V AA +A + +WP L R T Y+ + L C L+ H +K
Sbjct: 190 VSLQAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLIAHDNDVKEANKQRG 249
Query: 401 --APQHAQQSI 409
PQ AQ S+
Sbjct: 250 QAGPQSAQLSV 260
>gi|40805832 cyclin G1 [Homo sapiens]
Length = 295
Score = 62.8 bits (151), Expect = 6e-10
Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 9/143 (6%)
Query: 186 LREMEVKCKPKVGYMKKQPD-------ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNY 238
L E E +C+PKV ++ +T +R V L+ + + + ET LAVN
Sbjct: 20 LLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNL 79
Query: 239 IDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEH 296
+DRFLS M V L VG + LA K EE P + + I+ +T ++RME
Sbjct: 80 LDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139
Query: 297 LVLKVLTFDLAAPTVNQFLTQYF 319
+VL+ + + + A T QFL Y+
Sbjct: 140 IVLEKVCWKVKATTAFQFLQLYY 162
>gi|4757934 cyclin G1 [Homo sapiens]
Length = 295
Score = 62.8 bits (151), Expect = 6e-10
Identities = 46/143 (32%), Positives = 70/143 (48%), Gaps = 9/143 (6%)
Query: 186 LREMEVKCKPKVGYMKKQPD-------ITNSMRAILVDWLVEVGEEYKLQNETLHLAVNY 238
L E E +C+PKV ++ +T +R V L+ + + + ET LAVN
Sbjct: 20 LLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNL 79
Query: 239 IDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEH 296
+DRFLS M V L VG + LA K EE P + + I+ +T ++RME
Sbjct: 80 LDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEK 139
Query: 297 LVLKVLTFDLAAPTVNQFLTQYF 319
+VL+ + + + A T QFL Y+
Sbjct: 140 IVLEKVCWKVKATTAFQFLQLYY 162
>gi|94680985 cyclin J-like [Homo sapiens]
Length = 435
Score = 51.6 bits (122), Expect = 1e-06
Identities = 70/291 (24%), Positives = 106/291 (36%), Gaps = 79/291 (27%)
Query: 181 DIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYID 240
D+H LRE E+K + P + + R VD L + +L HLAV +D
Sbjct: 14 DVHCTLREKELKLPT---FRAHSPLLKS--RRFFVDILTLLSSHCQLCPAARHLAVYLLD 68
Query: 241 RFLSSMSVLRGK-LQLVGTAAMLLASKFEEIYP--------------------------- 272
F+ +V K L V + +LLA+ + P
Sbjct: 69 HFMDRYNVTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSSNSPASAP 128
Query: 273 ------PEVAEFVYITDD----------------------TYTKKQVLRMEHLVLKVLTF 304
P+VAE +D T TKK++L E L+L+ ++
Sbjct: 129 HPPPTPPQVAETTGKFEDREDHVPKLEQINSTRILSSQNFTLTKKELLSTELLLLEAFSW 188
Query: 305 DLAAPTVNQFLTQYFL----------HQQPANCK------VESLAMFLGELSLIDADPYL 348
+L PT FL Y L H P C ++ A + E++L D +
Sbjct: 189 NLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKTKECLKEYAHYFLEVTLQD-HIFY 247
Query: 349 KYLPSVIAGAAFHLA-LYTVTGQSWPESLIRKTGYTLESLKPCLMDLHQTY 398
K+ PSV+A A + + W L R + Y+LE L C+ L Y
Sbjct: 248 KFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVY 298
>gi|4757936 cyclin G2 [Homo sapiens]
Length = 344
Score = 51.2 bits (121), Expect = 2e-06
Identities = 41/146 (28%), Positives = 71/146 (48%), Gaps = 10/146 (6%)
Query: 182 IHTYLREMEVKCKPK---VGYMKKQPDITNSM----RAILVDWLVEVGEEYKLQNETLHL 234
++ YL E E + +P+ + ++ P+ N++ R V+ L + + ET L
Sbjct: 21 LNVYL-EQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVL 79
Query: 235 AVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQVL 292
AVN +DRFL+ M V L +G + LLA++ E+ P + + I+ T +
Sbjct: 80 AVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIK 139
Query: 293 RMEHLVLKVLTFDLAAPTVNQFLTQY 318
RME ++ + L ++L A T FL Y
Sbjct: 140 RMEKIISEKLHYELEATTALNFLHLY 165
>gi|5802992 cyclin I [Homo sapiens]
Length = 377
Score = 50.1 bits (118), Expect = 4e-06
Identities = 33/125 (26%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 194 KPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKL 253
K V M +++ S R ++ WL ++ ++ L ET LA + +DRFL+++ L
Sbjct: 28 KVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYL 87
Query: 254 QLVGTAAMLLASKFEEIYPPEVAEFVYITDDTY---TKKQVLRMEHLVLKVLTFDLAAPT 310
+ + LA+K E + + D++ + ++LRME ++L L +DL T
Sbjct: 88 SCIAISCFFLAAKTVE-EDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTAT 146
Query: 311 VNQFL 315
FL
Sbjct: 147 PLDFL 151
>gi|89886237 cyclin I family, member 2 [Homo sapiens]
Length = 369
Score = 48.9 bits (115), Expect = 9e-06
Identities = 34/118 (28%), Positives = 57/118 (48%), Gaps = 3/118 (2%)
Query: 201 KKQPDITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVLRGKLQLVGTAA 260
K Q +I ++ +++ WL+ + + T +LA+ R L S+ V L +
Sbjct: 141 KPQDEICDAFEEVVL-WLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITS 199
Query: 261 MLLASKF--EEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLT 316
+ LA+K EE + P+V +F Y+ ++LRME +L L +DL T FLT
Sbjct: 200 LRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLT 257
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/253 (21%), Positives = 101/253 (39%), Gaps = 21/253 (8%)
Query: 27 QEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVT 86
QE ++ + E+ Q R L + R L Q ++ R A L+D ++ E
Sbjct: 1391 QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450
Query: 87 VPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDY 146
V + KQ F + +A +EAQ++ + +K++RE + A SL ++ L D
Sbjct: 1451 VRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSL---KQQLEEKDM 1507
Query: 147 PMDGSFESPHTMDMSI----VLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVG--YM 200
+ G + +++ + E + S+ +V D+ +++ E + + G M
Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM 1567
Query: 201 KKQPDI-----------TNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVL 249
+Q + T+S D VE + Q + + V + + VL
Sbjct: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ-SCQKKLKQMEVQLEEEYEDKQKVL 1626
Query: 250 RGKLQLVGTAAML 262
R K +L G A L
Sbjct: 1627 REKRELEGKLATL 1639
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/253 (21%), Positives = 101/253 (39%), Gaps = 21/253 (8%)
Query: 27 QEDQENINPEKAAPVQQPRTRAALAVLKSGNPRGLAQQQRPKTRRVAPLKDLPVNDEHVT 86
QE ++ + E+ Q R L + R L Q ++ R A L+D ++ E
Sbjct: 1391 QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQ 1450
Query: 87 VPPWKANSKQPAFTIHVDEAEKEAQKKPAESQKIEREDALAFNSAISLPGPRKPLVPLDY 146
V + KQ F + +A +EAQ++ + +K++RE + A SL ++ L D
Sbjct: 1451 VRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSL---KQQLEEKDM 1507
Query: 147 PMDGSFESPHTMDMSI----VLEDEKPVSVNEVPDYHEDIHTYLREMEVKCKPKVG--YM 200
+ G + +++ + E + S+ +V D+ +++ E + + G M
Sbjct: 1508 DIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM 1567
Query: 201 KKQPDI-----------TNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRFLSSMSVL 249
+Q + T+S D VE + Q + + V + + VL
Sbjct: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ-SCQKKLKQMEVQLEEEYEDKQKVL 1626
Query: 250 RGKLQLVGTAAML 262
R K +L G A L
Sbjct: 1627 REKRELEGKLATL 1639
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,182,840
Number of Sequences: 37866
Number of extensions: 771466
Number of successful extensions: 2573
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 2492
Number of HSP's gapped (non-prelim): 88
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.