Guide to the Human Genome
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Search of human proteins with 4502539

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502539 voltage-dependent calcium channel gamma-1 subunit
[Homo sapiens]
         (222 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Ho...   459   e-130
gi|22027554 voltage-dependent calcium channel gamma-6 subunit is...   166   1e-41
gi|22027557 voltage-dependent calcium channel gamma-6 subunit is...   112   2e-25
gi|22027560 voltage-dependent calcium channel gamma-6 subunit is...    63   2e-10
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is...    48   8e-06
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso...    47   1e-05
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho...    45   4e-05
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H...    42   3e-04
gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho...    38   0.008
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho...    38   0.008
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ...    37   0.013
gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1 [...    37   0.013
gi|31377722 PERP, TP53 apoptosis effector [Homo sapiens]               36   0.023
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H...    35   0.051
gi|22748835 transmembrane protein 178 [Homo sapiens]                   32   0.33 
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]       31   0.74 
gi|226437592 transmembrane protein 114 [Homo sapiens]                  31   0.74 
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo...    31   0.96 
gi|93588657 claudin domain containing 1 protein isoform d [Homo ...    31   0.96 
gi|93588650 claudin domain containing 1 protein isoform a [Homo ...    31   0.96 
gi|93588620 claudin domain containing 1 protein isoform b [Homo ...    31   0.96 
gi|93588614 claudin domain containing 1 protein isoform a [Homo ...    31   0.96 
gi|93588624 claudin domain containing 1 protein isoform a [Homo ...    31   0.96 
gi|11096340 claudin domain containing 1 protein isoform a [Homo ...    31   0.96 
gi|6912500 phosphatidylinositol glycan anchor biosynthesis, clas...    30   1.3  
gi|29029537 phosphatidylinositol glycan anchor biosynthesis, cla...    30   1.3  
gi|169211272 PREDICTED: germ cell-specific gene 1-like protein 2...    29   2.8  
gi|169211660 PREDICTED: germ cell-specific gene 1-like protein 2...    29   2.8  
gi|169210878 PREDICTED: germ cell-specific gene 1-like protein 2...    29   2.8  
gi|112382285 exostoses-like 1 [Homo sapiens]                           29   3.7  

>gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Homo
           sapiens]
          Length = 222

 Score =  459 bits (1181), Expect = e-130
 Identities = 222/222 (100%), Positives = 222/222 (100%)

Query: 1   MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKR 60
           MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKR
Sbjct: 1   MSQTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKR 60

Query: 61  IPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIL 120
           IPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIL
Sbjct: 61  IPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIIL 120

Query: 121 GSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSW 180
           GSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSW
Sbjct: 121 GSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSW 180

Query: 181 SFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH 222
           SFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH
Sbjct: 181 SFACACAAFILLFLGGLALLLFSLPRMPRNPWESCMDAEPEH 222


>gi|22027554 voltage-dependent calcium channel gamma-6 subunit
           isoform a [Homo sapiens]
          Length = 260

 Score =  166 bits (421), Expect = 1e-41
 Identities = 84/211 (39%), Positives = 126/211 (59%), Gaps = 11/211 (5%)

Query: 8   KVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKR-----IP 62
           KV++ L     G  LA+ +V T+ W  L+ +  + +  CEAAH GLW+ CTKR     +P
Sbjct: 38  KVKLALLLAAVGATLAVLSVGTEFWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVP 97

Query: 63  MDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGS 122
           +D   TCGP  LPGE NC+YF+ F  GE++ IF+ TT+KE +++AA IA+  L  + LG 
Sbjct: 98  VDRD-TCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGC 156

Query: 123 LCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMI-----DSEDTVWIEYY 177
           LC+++ L K  ++LLR  ++ +  +GL +LVS+EV R SV+ ++     +      + Y 
Sbjct: 157 LCIIMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYE 216

Query: 178 YSWSFACACAAFILLFLGGLALLLFSLPRMP 208
           YSWS  C   A ++L LG    LL +LP  P
Sbjct: 217 YSWSLGCGVGAGLILLLGAGCFLLLTLPSWP 247


>gi|22027557 voltage-dependent calcium channel gamma-6 subunit
           isoform b [Homo sapiens]
          Length = 214

 Score =  112 bits (281), Expect = 2e-25
 Identities = 69/211 (32%), Positives = 97/211 (45%), Gaps = 57/211 (27%)

Query: 8   KVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKR-----IP 62
           KV++ L     G  LA+ +V T+ W  L+ +  + +  CEAAH GLW+ CTKR     +P
Sbjct: 38  KVKLALLLAAVGATLAVLSVGTEFWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVP 97

Query: 63  MDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGS 122
           + D  TCGP  LPGE NC+YF+ F  GE++ IF+ TT+K                     
Sbjct: 98  V-DRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKK--------------------- 135

Query: 123 LCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMI-----DSEDTVWIEYY 177
                                    GL +LVS+EV R SV+ ++     +      + Y 
Sbjct: 136 -------------------------GLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYE 170

Query: 178 YSWSFACACAAFILLFLGGLALLLFSLPRMP 208
           YSWS  C   A ++L LG    LL +LP  P
Sbjct: 171 YSWSLGCGVGAGLILLLGAGCFLLLTLPSWP 201


>gi|22027560 voltage-dependent calcium channel gamma-6 subunit
           isoform c [Homo sapiens]
          Length = 189

 Score = 63.2 bits (152), Expect = 2e-10
 Identities = 31/74 (41%), Positives = 43/74 (58%), Gaps = 6/74 (8%)

Query: 8   KVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRICTKR-----IP 62
           KV++ L     G  LA+ +V T+ W  L+ +  + +  CEAAH GLW+ CTKR     +P
Sbjct: 38  KVKLALLLAAVGATLAVLSVGTEFWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVP 97

Query: 63  MDDSKTCGPITLPG 76
           + D  TCGP  LPG
Sbjct: 98  V-DRDTCGPAELPG 110



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 5/66 (7%)

Query: 148 GLCILVSVEVMRQSVKRMI-----DSEDTVWIEYYYSWSFACACAAFILLFLGGLALLLF 202
           GL +LVS+EV R SV+ ++     +      + Y YSWS  C   A ++L LG    LL 
Sbjct: 111 GLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLL 170

Query: 203 SLPRMP 208
           +LP  P
Sbjct: 171 TLPSWP 176


>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
           isoform a [Homo sapiens]
          Length = 275

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 55/217 (25%), Positives = 94/217 (43%), Gaps = 35/217 (16%)

Query: 5   KMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHM---EHHNTTCEAA-HFGLWRICTKR 60
           K L +  ++F +  G+ L   AV TD+W  L   +   ++ +T  + + H GLWR+C   
Sbjct: 7   KALTLLSSVFAV-CGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCF-- 63

Query: 61  IPMDDSKTCGPITLPGEKN--CSYFRHFNPGESSEIFEFTTQKEYSI-SAAAIAIFSLGF 117
                        L GE+   C    +  P  +    E T      I SA    + SL F
Sbjct: 64  -------------LAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFF 110

Query: 118 IILGSLCVLLSLGKKRDY---LLRPASMFYAFAGLCILVSVEVMRQSVK-----RMIDSE 169
           + +G   +L ++G  R +   L   + +F+  +GL ++V + +   S+      R  D+E
Sbjct: 111 MFIGF--ILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAE 168

Query: 170 DTVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPR 206
              +  Y Y WSFA A  +F+L    G+  +   + R
Sbjct: 169 --TYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKR 203


>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
           isoform b [Homo sapiens]
          Length = 296

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 53/202 (26%), Positives = 89/202 (44%), Gaps = 35/202 (17%)

Query: 5   KMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHM---EHHNTTCEAA-HFGLWRICTKR 60
           K L +  ++F +  G+ L   AV TD+W  L   +   ++ +T  + + H GLWR+C   
Sbjct: 7   KALTLLSSVFAV-CGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCF-- 63

Query: 61  IPMDDSKTCGPITLPGEKN--CSYFRHFNPGESSEIFEFTTQKEYSI-SAAAIAIFSLGF 117
                        L GE+   C    +  P  +    E T      I SA    + SL F
Sbjct: 64  -------------LAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFF 110

Query: 118 IILGSLCVLLSLGKKRDY---LLRPASMFYAFAGLCILVSVEVMRQSVK-----RMIDSE 169
           + +G   +L ++G  R +   L   + +F+  +GL ++V + +   S+      R  D+E
Sbjct: 111 MFIGF--ILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAE 168

Query: 170 DTVWIEYYYSWSFACACAAFIL 191
              +  Y Y WSFA A  +F+L
Sbjct: 169 --TYFNYKYGWSFAFAAISFLL 188


>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
           sapiens]
          Length = 323

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 54/210 (25%), Positives = 84/210 (40%), Gaps = 30/210 (14%)

Query: 7   LKVRVTLFCILAGIVLAMTAVVTDHW----AVLSPHMEHHNTTCEA-----AHFGLWRIC 57
           +++ +T     A   L   AV TD+W     V        N T +       H GLWR C
Sbjct: 8   VQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTC 67

Query: 58  TKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGF 117
                      C      G   C    HF P ++   +E  T + +  +  A +IF +  
Sbjct: 68  -----------CLEGNFKGL--CKQIDHF-PEDAD--YEADTAEYFLRAVRASSIFPILS 111

Query: 118 IIL---GSLCVLLS-LGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVW 173
           +IL   G LC+  S   K R  ++  A +F+  AGL  ++ + V   +        D+  
Sbjct: 112 VILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKK 171

Query: 174 IEYYYSWSFACACAAFILL-FLGGLALLLF 202
             Y Y WSF     +FI+   +G LA+ +F
Sbjct: 172 NSYSYGWSFYFGALSFIIAEMVGVLAVHMF 201


>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
           sapiens]
          Length = 275

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 44/184 (23%), Positives = 76/184 (41%), Gaps = 26/184 (14%)

Query: 19  GIVLAMTAVVTDHWAVLSPH-MEHHNTTCE---AAHFGLWRICTKRIPMDDSKTCGPITL 74
           G++L   AV TD+W  +    +   N T E   A H GLWR+C                 
Sbjct: 20  GLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVC--------------FFA 65

Query: 75  PGEKN-CSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCVLLSLGK-- 131
             EK  C    +F   E + + E  T+        A     +   ++ +  V+ ++G   
Sbjct: 66  GREKGRCVASEYFLEPEINLVTE-NTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIR 124

Query: 132 -KRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMI---DSEDTVWIEYYYSWSFACACA 187
            +R  L   + +F+  +GL ++V + +   S+   +    S    +  Y Y WSFA A +
Sbjct: 125 PQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAAS 184

Query: 188 AFIL 191
           +F+L
Sbjct: 185 SFLL 188


>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
           sapiens]
          Length = 327

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 48/205 (23%), Positives = 79/205 (38%), Gaps = 38/205 (18%)

Query: 7   LKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHM-EHHNTTCE-----------AAHFGLW 54
           L++ +T     A   L   A+ TD+W   S H+    N T +             H GLW
Sbjct: 8   LQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLW 67

Query: 55  RICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAI-AIF 113
           R+C           C      G  +C    HF P ++    + +      + A+++  I 
Sbjct: 68  RVC-----------CIEGIYKG--HCFRINHF-PEDNDYDHDSSEYLLRIVRASSVFPIL 113

Query: 114 SLGFIILGSLCVLLS--LGKKRDYLLRPASMFYA-----FAGLCILVSVEVMRQSVKRMI 166
           S   ++LG LC+       +K + +L    +F A       G+ + +S      S KR  
Sbjct: 114 STILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDE 173

Query: 167 DSEDTVWIEYYYSWSFACACAAFIL 191
           D ++     Y Y WSF     +FI+
Sbjct: 174 DKKN----HYNYGWSFYFGALSFIV 194


>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
           sapiens]
          Length = 315

 Score = 37.7 bits (86), Expect = 0.008
 Identities = 50/205 (24%), Positives = 76/205 (37%), Gaps = 32/205 (15%)

Query: 7   LKVRVTLFCILAGIVLAMTAVVTDHW----AVLSPHMEHHNTTCEA-----AHFGLWRIC 57
           +++ +T     A   L   AV TD+W     V        N T         H GLWR C
Sbjct: 8   IQMLITTVGAFAAFSLMTIAVGTDYWLYSRGVCRTKSTSDNETSRKNEEVMTHSGLWRTC 67

Query: 58  TKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISA----AAIAIF 113
                      C      G   C    HF   E ++  + T   EY + A    +   I 
Sbjct: 68  -----------CLEGAFRGV--CKKIDHFP--EDADYEQDTA--EYLLRAVRASSVFPIL 110

Query: 114 SLGFIILGSLCVLLS-LGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTV 172
           S+  +  G LCV  S   + R  ++  A +F+  AGL  ++ + V   +        D+ 
Sbjct: 111 SVTLLFFGGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQRDSK 170

Query: 173 WIEYYYSWSFACACAAFILLFLGGL 197
              Y Y WSF     +FI+  + G+
Sbjct: 171 K-SYSYGWSFYFGAFSFIIAEIVGV 194


>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
          [Homo sapiens]
          Length = 173

 Score = 37.0 bits (84), Expect = 0.013
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 7/45 (15%)

Query: 13 LFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRIC 57
          LFC   G +L + A+ TDHW         +  +   AH GLWR C
Sbjct: 9  LFCAWVGTILLVVAMATDHWM-------QYRLSGSFAHQGLWRYC 46


>gi|21361300 lens intrinsic membrane protein 2, 19kDa isoform 1
          [Homo sapiens]
          Length = 215

 Score = 37.0 bits (84), Expect = 0.013
 Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 7/45 (15%)

Query: 13 LFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGLWRIC 57
          LFC   G +L + A+ TDHW         +  +   AH GLWR C
Sbjct: 9  LFCAWVGTILLVVAMATDHWM-------QYRLSGSFAHQGLWRYC 46


>gi|31377722 PERP, TP53 apoptosis effector [Homo sapiens]
          Length = 193

 Score = 36.2 bits (82), Expect = 0.023
 Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 9/136 (6%)

Query: 76  GEKNCSYFRHFNPGESSEIFEFTTQK--EYSISAAAIAIFSLGFIILGSLCVLLSL---- 129
           G+ +  +++    G  S  +E   Q   EY+   AA A+   GFIIL  +C +LS     
Sbjct: 42  GQTSSLWWKCSQEGGGSGSYEEGCQSLMEYAWGRAAAAMLFCGFIIL-VICFILSFFALC 100

Query: 130 GKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYYYSWSFACACAAF 189
           G +    LR      A A +  ++S+ +      +         + Y Y+W++    AA 
Sbjct: 101 GPQMLVFLRVIGGLLALAAVFQIISLVIYPVKYTQTFTLHANPAVTYIYNWAYGFGWAAT 160

Query: 190 ILLFLGGLALLLFSLP 205
           I+L   G A     LP
Sbjct: 161 IILI--GCAFFFCCLP 174


>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
           sapiens]
          Length = 425

 Score = 35.0 bits (79), Expect = 0.051
 Identities = 43/164 (26%), Positives = 66/164 (40%), Gaps = 31/164 (18%)

Query: 50  HFGLWRICTKRIPMDDSKTCGPITLPGEKN--CSYFRHFNPGESSEIFEFTTQKEYSISA 107
           H GLWRIC                L G K   C    HF P ++    +        + A
Sbjct: 84  HSGLWRIC---------------CLEGLKRGVCVKINHF-PEDTDYDHDSAEYLLRVVRA 127

Query: 108 AAI-AIFSLGFIILGSLCVLLS--LGKKRDYLLRPASMFYA-----FAGLCILVSVEVMR 159
           ++I  I S   ++LG +CV  S     KR+ +L    +F A       G+ + +S     
Sbjct: 128 SSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGE 187

Query: 160 QSVKRMIDSEDTVWIEYYYSWSFACACAAFILL-FLGGLALLLF 202
              KR  + ++     Y Y WSF     +FIL   +G LA+ ++
Sbjct: 188 PGPKRDEEKKN----HYSYGWSFYFGGLSFILAEVIGVLAVNIY 227


>gi|22748835 transmembrane protein 178 [Homo sapiens]
          Length = 297

 Score = 32.3 bits (72), Expect = 0.33
 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 9/81 (11%)

Query: 3  QTKMLKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHMEHHNTTCEAAHFGL-------WR 55
          + + L   ++L   L  + L +TA+ TDHW    P    H  +CE +  G          
Sbjct: 2  EPRALVTALSLGLSLCSLGLLVTAIFTDHWYETDP--RRHKESCERSRAGADPPDQKNRL 59

Query: 56 ICTKRIPMDDSKTCGPITLPG 76
          +    +P+ DS   G   LPG
Sbjct: 60 MPLSHLPLRDSPPLGRRLLPG 80


>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 31.2 bits (69), Expect = 0.74
 Identities = 42/203 (20%), Positives = 72/203 (35%), Gaps = 39/203 (19%)

Query: 21  VLAMTAVVTDHWAVL-SPHMEHHNTTCE--------------AAHFGLWRICTKRIPMDD 65
           VL   A+ TD W ++ +  +E      +              ++H GLWR C  + P   
Sbjct: 21  VLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSP--- 77

Query: 66  SKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCV 125
              C P+  P       FR  N   S    +  T      +   +   SL  ++ G +  
Sbjct: 78  ---CTPLMNP-------FRLENVTVSESSRQLLTMHG---TFVILLPLSLILMVFGGMTG 124

Query: 126 LLSLGKKRDYLLRPASMFYAFAGLCILVSVEV--------MRQSVKRMIDSEDTVWIEYY 177
            LS   +   LL    + + F  +  L  + V         R+++  + +      ++  
Sbjct: 125 FLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDIS 184

Query: 178 YSWSFACACAAFILLFLGGLALL 200
           + WS A    +FI   L G A L
Sbjct: 185 FGWSLALGWISFIAELLTGAAFL 207


>gi|226437592 transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 31.2 bits (69), Expect = 0.74
 Identities = 42/203 (20%), Positives = 72/203 (35%), Gaps = 39/203 (19%)

Query: 21  VLAMTAVVTDHWAVL-SPHMEHHNTTCE--------------AAHFGLWRICTKRIPMDD 65
           VL   A+ TD W ++ +  +E      +              ++H GLWR C  + P   
Sbjct: 21  VLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSP--- 77

Query: 66  SKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAIAIFSLGFIILGSLCV 125
              C P+  P       FR  N   S    +  T      +   +   SL  ++ G +  
Sbjct: 78  ---CTPLMNP-------FRLENVTVSESSRQLLTMHG---TFVILLPLSLILMVFGGMTG 124

Query: 126 LLSLGKKRDYLLRPASMFYAFAGLCILVSVEV--------MRQSVKRMIDSEDTVWIEYY 177
            LS   +   LL    + + F  +  L  + V         R+++  + +      ++  
Sbjct: 125 FLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDIS 184

Query: 178 YSWSFACACAAFILLFLGGLALL 200
           + WS A    +FI   L G A L
Sbjct: 185 FGWSLALGWISFIAELLTGAAFL 207


>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
           sapiens]
          Length = 217

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 35/161 (21%), Positives = 59/161 (36%), Gaps = 24/161 (14%)

Query: 48  AAHFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISA 107
           ++H GLWR C  + P      C P+  P       FR  N   S    +  T      + 
Sbjct: 57  SSHSGLWRTCRVQSP------CTPLMNP-------FRLENVTVSESSRQLLTMHG---TF 100

Query: 108 AAIAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEV--------MR 159
             +   SL  ++ G +   LS   +   LL    + + F  +  L  + V         R
Sbjct: 101 VILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFR 160

Query: 160 QSVKRMIDSEDTVWIEYYYSWSFACACAAFILLFLGGLALL 200
           +++  + +      ++  + WS A    +FI   L G A L
Sbjct: 161 EALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFL 201


>gi|93588657 claudin domain containing 1 protein isoform d [Homo
           sapiens]
          Length = 158

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 114 SLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVK---RMIDSED 170
           SLG +  G+L  L +   +  Y      + +  AGLC L SV      ++   + ++  D
Sbjct: 52  SLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPD 111

Query: 171 TVWIEYYYSWSFACACAAFILLFL 194
            V  E  + WSF  AC +  L F+
Sbjct: 112 NVSGE--FGWSFCLACVSAPLQFM 133


>gi|93588650 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 114 SLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVK---RMIDSED 170
           SLG +  G+L  L +   +  Y      + +  AGLC L SV      ++   + ++  D
Sbjct: 147 SLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPD 206

Query: 171 TVWIEYYYSWSFACACAAFILLFL 194
            V  E  + WSF  AC +  L F+
Sbjct: 207 NVSGE--FGWSFCLACVSAPLQFM 228


>gi|93588620 claudin domain containing 1 protein isoform b [Homo
           sapiens]
          Length = 276

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 114 SLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVK---RMIDSED 170
           SLG +  G+L  L +   +  Y      + +  AGLC L SV      ++   + ++  D
Sbjct: 170 SLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPD 229

Query: 171 TVWIEYYYSWSFACACAAFILLFL 194
            V  E  + WSF  AC +  L F+
Sbjct: 230 NVSGE--FGWSFCLACVSAPLQFM 251


>gi|93588614 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 114 SLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVK---RMIDSED 170
           SLG +  G+L  L +   +  Y      + +  AGLC L SV      ++   + ++  D
Sbjct: 147 SLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPD 206

Query: 171 TVWIEYYYSWSFACACAAFILLFL 194
            V  E  + WSF  AC +  L F+
Sbjct: 207 NVSGE--FGWSFCLACVSAPLQFM 228


>gi|93588624 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 114 SLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVK---RMIDSED 170
           SLG +  G+L  L +   +  Y      + +  AGLC L SV      ++   + ++  D
Sbjct: 147 SLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPD 206

Query: 171 TVWIEYYYSWSFACACAAFILLFL 194
            V  E  + WSF  AC +  L F+
Sbjct: 207 NVSGE--FGWSFCLACVSAPLQFM 228


>gi|11096340 claudin domain containing 1 protein isoform a [Homo
           sapiens]
          Length = 253

 Score = 30.8 bits (68), Expect = 0.96
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 5/84 (5%)

Query: 114 SLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVK---RMIDSED 170
           SLG +  G+L  L +   +  Y      + +  AGLC L SV      ++   + ++  D
Sbjct: 147 SLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPD 206

Query: 171 TVWIEYYYSWSFACACAAFILLFL 194
            V  E  + WSF  AC +  L F+
Sbjct: 207 NVSGE--FGWSFCLACVSAPLQFM 228


>gi|6912500 phosphatidylinositol glycan anchor biosynthesis, class N
           [Homo sapiens]
          Length = 931

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 20/87 (22%), Positives = 41/87 (47%)

Query: 118 IILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYY 177
           ++L SLCV+ SL K++D  ++   + +    L  ++S+ V+  +   ++  +    +   
Sbjct: 627 VLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQI 686

Query: 178 YSWSFACACAAFILLFLGGLALLLFSL 204
            SW+   +     LL    L   LFS+
Sbjct: 687 ISWATLASSLVVPLLSSPVLFQRLFSI 713


>gi|29029537 phosphatidylinositol glycan anchor biosynthesis, class
           N [Homo sapiens]
          Length = 931

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 20/87 (22%), Positives = 41/87 (47%)

Query: 118 IILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRMIDSEDTVWIEYY 177
           ++L SLCV+ SL K++D  ++   + +    L  ++S+ V+  +   ++  +    +   
Sbjct: 627 VLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQI 686

Query: 178 YSWSFACACAAFILLFLGGLALLLFSL 204
            SW+   +     LL    L   LFS+
Sbjct: 687 ISWATLASSLVVPLLSSPVLFQRLFSI 713


>gi|169211272 PREDICTED: germ cell-specific gene 1-like protein
           2-like [Homo sapiens]
          Length = 293

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 20/145 (13%)

Query: 50  HFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAA 109
           H GLW+ C + +  +D K            C  FR   P E   +   +   E       
Sbjct: 89  HVGLWQSCEESLNGEDEK------------CRSFRSVVPAEEQGVLWLSIGGE----VLD 132

Query: 110 IAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRM---I 166
           I +     I+LGS     S G     +    ++F   AGL  +V+  +M  ++ ++   +
Sbjct: 133 IVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVA-HMMYTTIFQITVNL 191

Query: 167 DSEDTVWIEYYYSWSFACACAAFIL 191
             ED     + Y WS+  A  +F L
Sbjct: 192 GPEDWKPQTWDYGWSYCLAWGSFAL 216


>gi|169211660 PREDICTED: germ cell-specific gene 1-like protein
           2-like [Homo sapiens]
          Length = 293

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 20/145 (13%)

Query: 50  HFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAA 109
           H GLW+ C + +  +D K            C  FR   P E   +   +   E       
Sbjct: 89  HVGLWQSCEESLNGEDEK------------CRSFRSVVPAEEQGVLWLSIGGE----VLD 132

Query: 110 IAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRM---I 166
           I +     I+LGS     S G     +    ++F   AGL  +V+  +M  ++ ++   +
Sbjct: 133 IVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVA-HMMYTTIFQITVNL 191

Query: 167 DSEDTVWIEYYYSWSFACACAAFIL 191
             ED     + Y WS+  A  +F L
Sbjct: 192 GPEDWKPQTWDYGWSYCLAWGSFAL 216


>gi|169210878 PREDICTED: germ cell-specific gene 1-like protein
           2-like [Homo sapiens]
          Length = 293

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 20/145 (13%)

Query: 50  HFGLWRICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAA 109
           H GLW+ C + +  +D K            C  FR   P E   +   +   E       
Sbjct: 89  HVGLWQSCEESLNGEDEK------------CRSFRSVVPAEEQGVLWLSIGGE----VLD 132

Query: 110 IAIFSLGFIILGSLCVLLSLGKKRDYLLRPASMFYAFAGLCILVSVEVMRQSVKRM---I 166
           I +     I+LGS     S G     +    ++F   AGL  +V+  +M  ++ ++   +
Sbjct: 133 IVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVA-HMMYTTIFQITVNL 191

Query: 167 DSEDTVWIEYYYSWSFACACAAFIL 191
             ED     + Y WS+  A  +F L
Sbjct: 192 GPEDWKPQTWDYGWSYCLAWGSFAL 216


>gi|112382285 exostoses-like 1 [Homo sapiens]
          Length = 676

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 12/53 (22%)

Query: 171 TVWIEYYYSWSFACACAAFILLFLGGLALLLFSLPRMPR----NPWESCMDAE 219
           ++W+    SW         +L+ LGG +LL  +LP  PR      W   +DAE
Sbjct: 9   SLWLALSASW--------LLLVLLGGFSLLRLALPPRPRPGASQGWPRWLDAE 53


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.138    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,401,005
Number of Sequences: 37866
Number of extensions: 345228
Number of successful extensions: 905
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 864
Number of HSP's gapped (non-prelim): 42
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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