Guide to the Human Genome
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Search of human proteins with 42734503

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42734503 membrane component chromosome 11 surface marker 1
isoform 2 [Homo sapiens]
         (694 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42734503 membrane component chromosome 11 surface marker 1 is...  1397   0.0  
gi|42558250 membrane component chromosome 11 surface marker 1 is...  1383   0.0  
gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]          222   1e-57
gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]          222   1e-57
gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens]          179   6e-45
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]      48   3e-05
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    48   3e-05
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    47   6e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     47   8e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          45   3e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          45   3e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          45   3e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          45   3e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          45   3e-04
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho...    44   5e-04
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    44   5e-04
gi|146134388 YLP motif containing 1 [Homo sapiens]                     44   5e-04
gi|56117844 synovial sarcoma translocation, chromosome 18 isofor...    43   9e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              43   9e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       43   0.001
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        43   0.001
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]            43   0.001
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]          43   0.001
gi|56117846 synovial sarcoma translocation, chromosome 18 isofor...    42   0.001
gi|24431935 reticulon 4 isoform A [Homo sapiens]                       42   0.001
gi|119943102 CREB binding protein isoform b [Homo sapiens]             42   0.001
gi|119943104 CREB binding protein isoform a [Homo sapiens]             42   0.001
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ...    42   0.001
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ...    42   0.001
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    42   0.001

>gi|42734503 membrane component chromosome 11 surface marker 1
           isoform 2 [Homo sapiens]
          Length = 694

 Score = 1397 bits (3616), Expect = 0.0
 Identities = 694/694 (100%), Positives = 694/694 (100%)

Query: 1   MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGV 60
           MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGV
Sbjct: 1   MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGV 60

Query: 61  IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALS 120
           IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALS
Sbjct: 61  IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALS 120

Query: 121 QDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSE 180
           QDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSE
Sbjct: 121 QDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSE 180

Query: 181 EELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERV 240
           EELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERV
Sbjct: 181 EELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERV 240

Query: 241 FQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFM 300
           FQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFM
Sbjct: 241 FQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFM 300

Query: 301 AETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQ 360
           AETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQ
Sbjct: 301 AETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQ 360

Query: 361 DLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQP 420
           DLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQP
Sbjct: 361 DLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQP 420

Query: 421 NQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTA 480
           NQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTA
Sbjct: 421 NQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTA 480

Query: 481 SSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQ 540
           SSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQ
Sbjct: 481 SSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQ 540

Query: 541 YQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRS 600
           YQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRS
Sbjct: 541 YQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRS 600

Query: 601 NQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPR 660
           NQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPR
Sbjct: 601 NQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPR 660

Query: 661 DYSGYQRDGYQQNFKRGSGQSGPRGAPRGNILWW 694
           DYSGYQRDGYQQNFKRGSGQSGPRGAPRGNILWW
Sbjct: 661 DYSGYQRDGYQQNFKRGSGQSGPRGAPRGNILWW 694


>gi|42558250 membrane component chromosome 11 surface marker 1
           isoform 1 [Homo sapiens]
          Length = 709

 Score = 1383 bits (3580), Expect = 0.0
 Identities = 689/689 (100%), Positives = 689/689 (100%)

Query: 1   MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGV 60
           MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGV
Sbjct: 1   MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGV 60

Query: 61  IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALS 120
           IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALS
Sbjct: 61  IDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALS 120

Query: 121 QDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSE 180
           QDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSE
Sbjct: 121 QDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSE 180

Query: 181 EELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERV 240
           EELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERV
Sbjct: 181 EELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERV 240

Query: 241 FQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFM 300
           FQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFM
Sbjct: 241 FQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFM 300

Query: 301 AETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQ 360
           AETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQ
Sbjct: 301 AETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQ 360

Query: 361 DLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQP 420
           DLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQP
Sbjct: 361 DLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQP 420

Query: 421 NQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTA 480
           NQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTA
Sbjct: 421 NQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTA 480

Query: 481 SSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQ 540
           SSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQ
Sbjct: 481 SSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQ 540

Query: 541 YQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRS 600
           YQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRS
Sbjct: 541 YQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRS 600

Query: 601 NQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPR 660
           NQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPR
Sbjct: 601 NQPYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSAPR 660

Query: 661 DYSGYQRDGYQQNFKRGSGQSGPRGAPRG 689
           DYSGYQRDGYQQNFKRGSGQSGPRGAPRG
Sbjct: 661 DYSGYQRDGYQQNFKRGSGQSGPRGAPRG 689


>gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]
          Length = 1127

 Score =  222 bits (565), Expect = 1e-57
 Identities = 162/524 (30%), Positives = 244/524 (46%), Gaps = 41/524 (7%)

Query: 2   PSATSHSGSGSKSS--GPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILG 59
           PSA+S S     SS  G   PSG S  E      +A P   H   G        ++  L 
Sbjct: 50  PSASSVSMVQLFSSPFGYQSPSGHSEEEREGNMKSAKPQVNHSQHGESQRALSPLQSTLS 109

Query: 60  ------------------VIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQE 101
                              +  K+RN+EKKK KL+DY++R+  GE LN DQL+AV KY+E
Sbjct: 110 SAASPSQAYETYIENGLICLKHKIRNIEKKKLKLEDYKDRLKSGEHLNPDQLEAVEKYEE 169

Query: 102 VTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGD 161
           V +NLEFAKELQ++F  LS D+ K  KK  RRE +++ EAE+K+L+T+L++QYVL  L  
Sbjct: 170 VLHNLEFAKELQKTFSGLSLDLLKAQKKAQRREHMLKLEAEKKKLRTILQVQYVLQNLTQ 229

Query: 162 DEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGK 221
           + V+ D K GLNG   L  +EL  L +F KL  PER+ SL + +Q E +S++ WDLLEG 
Sbjct: 230 EHVQKDFKGGLNGAVYLPSKELDYLIKFSKLTCPERNESLSVEDQMEQSSLYFWDLLEGS 289

Query: 222 EKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAE 281
           EK V GTTYK LK+++ ++  S YF+S    +N   +E+E    P  E+ + ++E +   
Sbjct: 290 EKAVVGTTYKHLKDLLSKLLNSGYFESIPVPKN--AKEKE---VPLEEEMLIQSEKKTQL 344

Query: 282 EYTE------------QSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQ 329
             TE            Q E++  E++NR++M E  +++ + E+   W  +     N  ++
Sbjct: 345 SKTESVKESESLMEFAQPEIQPQEFLNRRYMTEVDYSNKQGEE-QPWEADYARKPNLPKR 403

Query: 330 QPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAI 389
                 P   E          +   + Q V      ++               +     I
Sbjct: 404 WDMLTEPDGQEKKQ-ESFKSWEASGKHQEVSKPAVSLEQRKQDTSKLRSTLPEEQKKQEI 462

Query: 390 VSAQPMNPTQNMDMPQLVCPPVHSESRLAQ-PNQVPVQPEATQVPLVSSTSEGYTASQPL 448
             ++P       D P+     V  E +  + P   PVQ +  Q P    T + +T S   
Sbjct: 463 SKSKPSPSQWKQDTPKSKAGYVQEEQKKQETPKLWPVQLQKEQDP-KKQTPKSWTPSMQS 521

Query: 449 YQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQV 492
            Q +  +   P  E  D  Q     + +    S      SQ Q+
Sbjct: 522 EQNTTKSWTTPMCEEQDSKQPETPKSWENNVESQKHSLTSQSQI 565



 Score =  180 bits (457), Expect = 3e-45
 Identities = 149/448 (33%), Positives = 218/448 (48%), Gaps = 62/448 (13%)

Query: 264 SAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEV 323
           + P  E+Q    +PE  + +  ++ VES ++           TS  +     W V T  +
Sbjct: 530 TTPMCEEQ-DSKQPETPKSW--ENNVESQKH---------SLTSQSQISPKSWGVATASL 577

Query: 324 V-------NSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDS 376
           +         L  +P+     V +P   +     DP++R++++QDLM Q+QG  NF+Q+S
Sbjct: 578 IPNDQLLPRKLNTEPKDVPKPVHQPVGSSSTLPKDPVLRKEKLQDLMTQIQGTCNFMQES 637

Query: 377 MLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQP-EATQVPLV 435
           +LDF+  +   AI ++QP + T          P    E  L+  +    +P +AT  P+ 
Sbjct: 638 VLDFDKPS--SAIPTSQPPSATPGS-------PVASKEQNLSSQSDFLQEPLQATSSPVT 688

Query: 436 SSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLP--AASQPQVF 493
            S++     +      S  TE    + P    +A I      ++ +S  P  A    Q F
Sbjct: 689 CSSNACLVTTDQASSGSE-TEFMTSETP----EAAIPPGKQPSSLASPNPPMAKGSEQGF 743

Query: 494 QAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSS-- 551
           Q   S P  SS + +N APFQ+MQTVFN+NAP+PP  E E   +++ Y   YNQSF++  
Sbjct: 744 Q---SPPASSSSVTINTAPFQAMQTVFNVNAPLPPRKEQEI--KESPYSPGYNQSFTTAS 798

Query: 552 --QPHQVEQTELQQEQL---QTVVGTYHGSPDQSHQVT-GNHQQPPQQNTGFPRSNQPYY 605
              P Q +   +  EQ    Q     YH  PD + QV+ G+    P Q   FPR  QP+ 
Sbjct: 799 TQTPPQCQLPSIHVEQTVHSQETAANYH--PDGTIQVSNGSLAFYPAQTNVFPRPTQPFV 856

Query: 606 NSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYR--PSFSNTPNSGYTQSQFSAPRDYS 663
           NSRG  RG +RG R + N YR P  G++ G+D YR  PS S   N  Y+Q QF A R+YS
Sbjct: 857 NSRGSVRGCTRGGRLITNSYRSP-GGYK-GFDTYRGLPSIS---NGNYSQLQFQA-REYS 910

Query: 664 G---YQRDGYQQNFKRGSGQSGPRGAPR 688
           G    QRD +QQ +KRG    GPR   R
Sbjct: 911 GAPYSQRDNFQQCYKRGGTSGGPRANSR 938


>gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]
          Length = 1077

 Score =  222 bits (565), Expect = 1e-57
 Identities = 162/524 (30%), Positives = 244/524 (46%), Gaps = 41/524 (7%)

Query: 2   PSATSHSGSGSKSS--GPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILG 59
           PSA+S S     SS  G   PSG S  E      +A P   H   G        ++  L 
Sbjct: 50  PSASSVSMVQLFSSPFGYQSPSGHSEEEREGNMKSAKPQVNHSQHGESQRALSPLQSTLS 109

Query: 60  ------------------VIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQE 101
                              +  K+RN+EKKK KL+DY++R+  GE LN DQL+AV KY+E
Sbjct: 110 SAASPSQAYETYIENGLICLKHKIRNIEKKKLKLEDYKDRLKSGEHLNPDQLEAVEKYEE 169

Query: 102 VTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGD 161
           V +NLEFAKELQ++F  LS D+ K  KK  RRE +++ EAE+K+L+T+L++QYVL  L  
Sbjct: 170 VLHNLEFAKELQKTFSGLSLDLLKAQKKAQRREHMLKLEAEKKKLRTILQVQYVLQNLTQ 229

Query: 162 DEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGK 221
           + V+ D K GLNG   L  +EL  L +F KL  PER+ SL + +Q E +S++ WDLLEG 
Sbjct: 230 EHVQKDFKGGLNGAVYLPSKELDYLIKFSKLTCPERNESLSVEDQMEQSSLYFWDLLEGS 289

Query: 222 EKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAE 281
           EK V GTTYK LK+++ ++  S YF+S    +N   +E+E    P  E+ + ++E +   
Sbjct: 290 EKAVVGTTYKHLKDLLSKLLNSGYFESIPVPKN--AKEKE---VPLEEEMLIQSEKKTQL 344

Query: 282 EYTE------------QSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQ 329
             TE            Q E++  E++NR++M E  +++ + E+   W  +     N  ++
Sbjct: 345 SKTESVKESESLMEFAQPEIQPQEFLNRRYMTEVDYSNKQGEE-QPWEADYARKPNLPKR 403

Query: 330 QPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAI 389
                 P   E          +   + Q V      ++               +     I
Sbjct: 404 WDMLTEPDGQEKKQ-ESFKSWEASGKHQEVSKPAVSLEQRKQDTSKLRSTLPEEQKKQEI 462

Query: 390 VSAQPMNPTQNMDMPQLVCPPVHSESRLAQ-PNQVPVQPEATQVPLVSSTSEGYTASQPL 448
             ++P       D P+     V  E +  + P   PVQ +  Q P    T + +T S   
Sbjct: 463 SKSKPSPSQWKQDTPKSKAGYVQEEQKKQETPKLWPVQLQKEQDP-KKQTPKSWTPSMQS 521

Query: 449 YQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQV 492
            Q +  +   P  E  D  Q     + +    S      SQ Q+
Sbjct: 522 EQNTTKSWTTPMCEEQDSKQPETPKSWENNVESQKHSLTSQSQI 565



 Score =  142 bits (359), Expect = 8e-34
 Identities = 132/444 (29%), Positives = 197/444 (44%), Gaps = 104/444 (23%)

Query: 264 SAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEV 323
           + P  E+Q    +PE  + +  ++ VES ++           TS  +     W V T  +
Sbjct: 530 TTPMCEEQ-DSKQPETPKSW--ENNVESQKH---------SLTSQSQISPKSWGVATASL 577

Query: 324 V-------NSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDS 376
           +         L  +P+     V +P   +     DP++R++++QDLM Q+QG  NF+Q+S
Sbjct: 578 IPNDQLLPRKLNTEPKDVPKPVHQPVGSSSTLPKDPVLRKEKLQDLMTQIQGTCNFMQES 637

Query: 377 MLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVS 436
           +LDF+  +   AI ++QP                         P+  P  P A++   +S
Sbjct: 638 VLDFDKPS--SAIPTSQP-------------------------PSATPGSPVASKEQNLS 670

Query: 437 STSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAG 496
           S S+       L +P  AT       P+        + TDQ ++ S              
Sbjct: 671 SQSDF------LQEPLQATSS-----PVTCSSNACLVTTDQASSGSE------------- 706

Query: 497 TSKPLHSSGINVNAAPFQSMQT--VFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQ-- 552
                           F + +T  VFN+NAP+PP  E E   +++ Y   YNQSF++   
Sbjct: 707 --------------TEFMTSETPEVFNVNAPLPPRKEQEI--KESPYSPGYNQSFTTAST 750

Query: 553 --PHQVEQTELQQEQLQTVVGTYHGSPDQSHQVT-GNHQQPPQQNTGFPRSNQPYYNSRG 609
             P Q +   +  EQ      T +  PD + QV+ G+    P Q   FPR  QP+ NSRG
Sbjct: 751 QTPPQCQLPSIHVEQTVHSQETANYHPDGTIQVSNGSLAFYPAQTNVFPRPTQPFVNSRG 810

Query: 610 VSRGGSRGARGLMNGYRGPANGFRGGYDGYR--PSFSNTPNSGYTQSQFSAPRDYSG--- 664
             RG +RG R + N YR P  G++ G+D YR  PS S   N  Y+Q QF A R+YSG   
Sbjct: 811 SVRGCTRGGRLITNSYRSP-GGYK-GFDTYRGLPSIS---NGNYSQLQFQA-REYSGAPY 864

Query: 665 YQRDGYQQNFKRGSGQSGPRGAPR 688
            QRD +QQ +KRG    GPR   R
Sbjct: 865 SQRDNFQQCYKRGGTSGGPRANSR 888


>gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens]
          Length = 793

 Score =  179 bits (455), Expect = 6e-45
 Identities = 147/445 (33%), Positives = 217/445 (48%), Gaps = 57/445 (12%)

Query: 264 SAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEV 323
           + P  E+Q    +PE  + +  ++ VES ++           TS  +     W V T  +
Sbjct: 197 TTPMCEEQ-DSKQPETPKSW--ENNVESQKH---------SLTSQSQISPKSWGVATASL 244

Query: 324 V-------NSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDS 376
           +         L  +P+     V +P   +     DP++R++++QDLM Q+QG  NF+Q+S
Sbjct: 245 IPNDQLLPRKLNTEPKDVPKPVHQPVGSSSTLPKDPVLRKEKLQDLMTQIQGTCNFMQES 304

Query: 377 MLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQP-EATQVPLV 435
           +LDF+  +   AI ++QP + T          P    E  L+  +    +P +AT  P+ 
Sbjct: 305 VLDFDKPS--SAIPTSQPPSATPGS-------PVASKEQNLSSQSDFLQEPLQATSSPVT 355

Query: 436 SSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLP--AASQPQVF 493
            S++     +      S  TE    + P    +A I      ++ +S  P  A    Q F
Sbjct: 356 CSSNACLVTTDQASSGSE-TEFMTSETP----EAAIPPGKQPSSLASPNPPMAKGSEQGF 410

Query: 494 QAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSS-- 551
           Q   S P  SS + +N APFQ+MQTVFN+NAP+PP  E E   +++ Y   YNQSF++  
Sbjct: 411 Q---SPPASSSSVTINTAPFQAMQTVFNVNAPLPPRKEQEI--KESPYSPGYNQSFTTAS 465

Query: 552 --QPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVT-GNHQQPPQQNTGFPRSNQPYYNSR 608
              P Q +   +  EQ      T +  PD + QV+ G+    P Q   FPR  QP+ NSR
Sbjct: 466 TQTPPQCQLPSIHVEQTVHSQETANYHPDGTIQVSNGSLAFYPAQTNVFPRPTQPFVNSR 525

Query: 609 GVSRGGSRGARGLMNGYRGPANGFRGGYDGYR--PSFSNTPNSGYTQSQFSAPRDYSG-- 664
           G  RG +RG R + N YR P  G++ G+D YR  PS S   N  Y+Q QF A R+YSG  
Sbjct: 526 GSVRGCTRGGRLITNSYRSP-GGYK-GFDTYRGLPSIS---NGNYSQLQFQA-REYSGAP 579

Query: 665 -YQRDGYQQNFKRGSGQSGPRGAPR 688
             QRD +QQ +KRG    GPR   R
Sbjct: 580 YSQRDNFQQCYKRGGTSGGPRANSR 604


>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
          Length = 2382

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 102/476 (21%), Positives = 172/476 (36%), Gaps = 81/476 (17%)

Query: 64  KLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDI 123
           ++ +++K KGK  D  E +     L +D  + V+  QE+  +    +   ++     +D 
Sbjct: 505 RIEDIKKLKGKYKD-NEAIEFSFDLERDVPEDVA--QEMVESGYVCEGDHKTMAKAIKDR 561

Query: 124 QKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEEL 183
              IK+   + QL+REE E+K+ +     Q V            L     G+P  S    
Sbjct: 562 VSLIKRKREQRQLVREEQEKKKQEESSLKQQVEQSSASQTGIKQLPSASTGIPTASTTSA 621

Query: 184 SLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQS 243
           S+  +  +  +PE D   +L  QY+  SI +  L +G      G++          VF  
Sbjct: 622 SVSTQ-VEPEEPEADQHQQL--QYQQPSISV--LSDGTVDSGQGSS----------VFTE 666

Query: 244 NYFDSTHNHQNGLCEEEEAASAPAVEDQVP---EAEPEPAEEYTEQSEVESTEYVNRQFM 300
           +   S      G  + E+A S   V   +P   +A+ +P   Y   S             
Sbjct: 667 SRVSSQQTVSYG-SQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVA----------- 714

Query: 301 AETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQ 360
                                          Q  S   P   SLT V+ + P+   Q+ Q
Sbjct: 715 -------------------------------QGQSQGQPSSSSLTGVSSSQPIQHPQQQQ 743

Query: 361 DLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQP 420
            +  Q   P   +Q S+      +      +AQP++  Q    PQ V P V +  +L   
Sbjct: 744 GIQ-QTAPPQQTVQYSL---SQTSTSSEATTAQPVSQPQ---APQ-VLPQVSAGKQLPVS 795

Query: 421 NQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRP--QKEPIDQIQATISLNTDQT 478
             VP      Q+P+ +  S     S   + P       P   + P+ QI  +    +   
Sbjct: 796 QPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPLLPQYPVSQIPISTPHVSTAQ 855

Query: 479 TASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPET 534
           T  SSLP         AG ++PL +   +   A    + TV  + + +P + +P T
Sbjct: 856 TGFSSLPI-----TMAAGITQPLLTLASSATTAAIPGVSTV--VPSQLPTLLQPVT 904


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 71/295 (24%), Positives = 103/295 (34%), Gaps = 62/295 (21%)

Query: 323  VVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLD--- 379
            V N     P A  P  P P    P +Q  P   R R+ +          F + SM     
Sbjct: 2194 VTNQRHSDPYAHPPGTPRPGISVPYSQP-PATPRPRISE---------GFTRSSMTRPVL 2243

Query: 380  FENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTS 439
              NQ  DP + +AQ   P     +P  +  P  + S+  +P                   
Sbjct: 2244 MPNQ--DPFLQAAQNRGPA----LPGPLVRPPDTCSQTPRP-----------------PG 2280

Query: 440  EGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQT-TASSSLPAASQPQV-----F 493
             G + +     PS A      ++P DQ   T    +D   T+ ++   A QP+      F
Sbjct: 2281 PGLSDTFSRVSPSAA------RDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSF 2334

Query: 494  QAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQP 553
             A ++ P+HS G        Q    V  +  PVP     +T    N  QA   +    Q 
Sbjct: 2335 CASSNSPMHSQG--------QQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKL--RQR 2384

Query: 554  HQVEQTELQQEQLQTVVGTYH----GSPDQSHQVTGNHQQPPQQNTGFPRSNQPY 604
             ++ +  LQQ+Q + + G        SP   H     H QP   N  F R   PY
Sbjct: 2385 QKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPY 2439



 Score = 29.6 bits (65), Expect = 9.8
 Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 9/73 (12%)

Query: 420  PNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPI--DQIQATISLNTDQ 477
            PNQ+PV P+  QVP  S   +G++        S +   R    P+  +  +A +S +   
Sbjct: 2616 PNQLPVHPDLEQVP-PSQQEQGHSVH------SSSMVMRTLNHPLGGEFSEAPLSTSVPS 2668

Query: 478  TTASSSLPAASQP 490
             T S +L   +QP
Sbjct: 2669 ETTSDNLQITTQP 2681


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 113/598 (18%), Positives = 192/598 (32%), Gaps = 72/598 (12%)

Query: 18   PPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQI---LGVIDKKLRNLEKKKGK 74
            PP S  S S++++ + ++   S+       A   E +K +   L  + +  +N  KKK K
Sbjct: 482  PPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEK 541

Query: 75   LDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARRE 134
             D  +++  K +R  + + +  SK +E             S ++  +      K     E
Sbjct: 542  -DKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600

Query: 135  QLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVD 194
                ++ +    +   +L   ++KL  +++   +    +  P L       ++  ++ + 
Sbjct: 601  SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660

Query: 195  PERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQN 254
            P    +LR  E+Y      +   L  K KP       +      + F S+  +S+    +
Sbjct: 661  PS---TLRELERY------VTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSS 711

Query: 255  GLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVD 314
               E+ E   AP  + +      +    +    +++                        
Sbjct: 712  SDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAP--------------------- 750

Query: 315  EWTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQ 374
                    V       PQ   P  P      P     P    Q+    M     P+   Q
Sbjct: 751  ------APVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQ 804

Query: 375  DSMLD--FENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQV 432
              +L+        DP     QP+     + +PQ   PP      L QP +    P   Q 
Sbjct: 805  VPVLEPQLPGSVFDPIGHFTQPI-----LHLPQPELPP-----HLPQPPEHSTPPHLNQH 854

Query: 433  PLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQV 492
             +VS  +      Q   +PS+     P   P       +S    QT      P A  PQV
Sbjct: 855  AVVSPPALHNALPQQPSRPSNRAAALP---PKPARPPAVSPALTQTPLLPQPPMAQPPQV 911

Query: 493  FQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQ 552
                   P         A P  SMQ    +   +  V  P  L    + Q+         
Sbjct: 912  LLEDEEPP---------APPLTSMQMQLYLQ-QLQKVQPPTPLLPSVKVQSQPPPPLPPP 961

Query: 553  PHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGN--HQQPPQQNTGF-----PRSNQP 603
            PH   Q +LQQ+            P Q HQ      H QP Q +T       P+  QP
Sbjct: 962  PHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP 1019


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 75/346 (21%), Positives = 135/346 (39%), Gaps = 70/346 (20%)

Query: 69   EKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNL--------EFAKELQRSFMALS 120
            +K + +L + Q + N+GER+  +  D V+K Q   +N+          + +L + F AL 
Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALE 1307

Query: 121  QDIQKT----------------------IKKTARREQLMREEAEQKRLKTVL-----ELQ 153
              +Q T                       +K + REQL  EE  +  L+  +     ++ 
Sbjct: 1308 SQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVA 1367

Query: 154  YVLDKLGD--------DEVRTDLKQGLNGVPILSEEELSLLDEFYK----LVDPERDMSL 201
             +  K+ D        +EV+  L++ L G+    EE+++  D+  K    L     D+ +
Sbjct: 1368 DMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLV 1427

Query: 202  RLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEE 261
             L+ Q + A       LE K+K       ++L E  E+   + Y            EE +
Sbjct: 1428 DLDHQRQSAC-----NLEKKQKKF----DQLLAE--EKTISAKY-----------AEERD 1465

Query: 262  AASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETV 321
             A A A E +        A E   + + E  E +N+QF  E +     K+ V +   E  
Sbjct: 1466 RAEAEAREKETKALSLARALEEAMEQKAE-LERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524

Query: 322  EVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQ 367
            +   +L+QQ +     + E        +   L     +Q + AQ +
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFE 1570



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 61/272 (22%), Positives = 114/272 (41%), Gaps = 32/272 (11%)

Query: 62   DKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQ 121
            + KL+ LE+++  L+D   ++ K ++L +D++       E T NL   +E  +S   L  
Sbjct: 970  EAKLKKLEEEQIILEDQNCKLAKEKKLLEDRI------AEFTTNLTEEEEKSKSLAKLKN 1023

Query: 122  DIQKTI---KKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVR-TDLKQGLNGVPI 177
              +  I   ++  RRE+  R+E E+ R K   +   + D++ + + +  +LK  L     
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQL----A 1079

Query: 178  LSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEG---------KEKPVCGT 228
              EEEL       +    +++M+L+   + E     L + LE          K+K   G 
Sbjct: 1080 KKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGE 1139

Query: 229  TYKVLKEIVERVFQS----NYFDSTHNHQNGLCE---EEEAASAPAVEDQVPEAEPEPAE 281
              + LK  +E    S        S    +  + +   EEEA +  A   ++ +   +  E
Sbjct: 1140 ELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVE 1199

Query: 282  EYTEQSEVESTEYVNRQFMAETQFTSGEKEQV 313
            E  EQ  +E T+ V        Q    E+ ++
Sbjct: 1200 ELAEQ--LEQTKRVKANLEKAKQTLENERGEL 1229


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 71/293 (24%), Positives = 101/293 (34%), Gaps = 19/293 (6%)

Query: 329 QQPQAASPSVPEP-HSLTPVAQADPLVRRQRVQDLMAQMQGPYN--FIQDSMLDFENQTL 385
           QQP    P   +P H  +    A P  +   +   +AQ  G                Q L
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366

Query: 386 DPAIVSAQPMN---PTQNMDMPQLVCPPVHSESRLAQ---PNQVPVQPEATQVPLVSSTS 439
            PA   AQ      P+     P+ +  P       AQ   P + P Q   T  PL     
Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426

Query: 440 EGYTASQPLYQPSHATEQRPQKEPIDQIQA--TISLNTDQTTASSSLPAASQPQVFQAGT 497
               A  P    +   +  P K P  Q     T +  T  T   S LP  ++P   Q G 
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486

Query: 498 SKPLHSSGINVNAAPFQSMQTVFNMNAP---VPPVNEPETLKQQNQYQASYNQSFSSQPH 554
           +KP      +      Q   T      P    P   +P + K  +Q   S   S + QP 
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS-AQQPS 545

Query: 555 QVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNS 607
             + +   Q+  + V  T  G P Q   V+ + +QPP Q  G P++  P  N+
Sbjct: 546 PAKPS--AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ--GLPKTICPLCNT 594



 Score = 33.1 bits (74), Expect = 0.89
 Identities = 58/246 (23%), Positives = 88/246 (35%), Gaps = 38/246 (15%)

Query: 273 PEAEP-EPAEEYTEQ--SEVESTEYVNRQFMAETQF---TSGEKEQVDEWTVETVEVVNS 326
           P A+P  PA+   +Q  SE  S+E    + +A+      T  ++    +   + V     
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420

Query: 327 LQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLD 386
           L QQP   SP+     + TPV Q  P         + AQ  G                  
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGP-------GKIPAQQAG------------------ 455

Query: 387 PAIVSAQPMNPTQ-NMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTAS 445
           P   SAQ   PT+    +P    PP         P   P QP + + P     S      
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP---PQQPGSAKPPSQQPGSTKPPPQ 512

Query: 446 QPLYQPSHATEQRP-QKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSS 504
           QP   P+  + Q+P   +P  Q   +   +  Q + +      S   V Q G+ KPL   
Sbjct: 513 QP--GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570

Query: 505 GINVNA 510
            ++ +A
Sbjct: 571 TVSPSA 576



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 413  SESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATIS 472
            S S   +P  +P+     ++P+V+  SE  +   P+ QP      R    P+  I A   
Sbjct: 4332 SSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMA--RAAAGPLPPISAD-- 4387

Query: 473  LNTDQTTASSSLPAASQ 489
               DQ  +S SLP   Q
Sbjct: 4388 -TRDQFGSSHSLPEVQQ 4403



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 45/217 (20%), Positives = 83/217 (38%), Gaps = 13/217 (5%)

Query: 260  EEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQF----TSGEKEQVDE 315
            ++   APA E   P+AE  P  + TE  +       ++   AE Q     T  EK    E
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056

Query: 316  WTVETVEV-VNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQ 374
             T    +  +N   + P   +      + +  +   +P      +Q+ +         I 
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116

Query: 375  DSMLDFENQTLDPAIVSAQPMN-PTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVP 433
              + D       P+   A PM  PT++      V P V    +L +  +  V+ EA +V 
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQV----KLVKKQEQEVKTEAEKV- 1171

Query: 434  LVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQAT 470
            ++    E  T S     P   T+Q+ ++  +++ +A+
Sbjct: 1172 ILEKVKE--TLSMEKIPPMVTTDQKQEESKLEKDKAS 1206


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 71/293 (24%), Positives = 101/293 (34%), Gaps = 19/293 (6%)

Query: 329 QQPQAASPSVPEP-HSLTPVAQADPLVRRQRVQDLMAQMQGPYN--FIQDSMLDFENQTL 385
           QQP    P   +P H  +    A P  +   +   +AQ  G                Q L
Sbjct: 307 QQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL 366

Query: 386 DPAIVSAQPMN---PTQNMDMPQLVCPPVHSESRLAQ---PNQVPVQPEATQVPLVSSTS 439
            PA   AQ      P+     P+ +  P       AQ   P + P Q   T  PL     
Sbjct: 367 GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPG 426

Query: 440 EGYTASQPLYQPSHATEQRPQKEPIDQIQA--TISLNTDQTTASSSLPAASQPQVFQAGT 497
               A  P    +   +  P K P  Q     T +  T  T   S LP  ++P   Q G 
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGP 486

Query: 498 SKPLHSSGINVNAAPFQSMQTVFNMNAP---VPPVNEPETLKQQNQYQASYNQSFSSQPH 554
           +KP      +      Q   T      P    P   +P + K  +Q   S   S + QP 
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS-AQQPS 545

Query: 555 QVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNS 607
             + +   Q+  + V  T  G P Q   V+ + +QPP Q  G P++  P  N+
Sbjct: 546 PAKPS--AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQ--GLPKTICPLCNT 594



 Score = 33.1 bits (74), Expect = 0.89
 Identities = 58/246 (23%), Positives = 88/246 (35%), Gaps = 38/246 (15%)

Query: 273 PEAEP-EPAEEYTEQ--SEVESTEYVNRQFMAETQF---TSGEKEQVDEWTVETVEVVNS 326
           P A+P  PA+   +Q  SE  S+E    + +A+      T  ++    +   + V     
Sbjct: 361 PPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420

Query: 327 LQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLD 386
           L QQP   SP+     + TPV Q  P         + AQ  G                  
Sbjct: 421 LAQQPGLQSPAKAPGPTKTPVQQPGP-------GKIPAQQAG------------------ 455

Query: 387 PAIVSAQPMNPTQ-NMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTAS 445
           P   SAQ   PT+    +P    PP         P   P QP + + P     S      
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP---PQQPGSAKPPSQQPGSTKPPPQ 512

Query: 446 QPLYQPSHATEQRP-QKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSS 504
           QP   P+  + Q+P   +P  Q   +   +  Q + +      S   V Q G+ KPL   
Sbjct: 513 QP--GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570

Query: 505 GINVNA 510
            ++ +A
Sbjct: 571 TVSPSA 576



 Score = 31.6 bits (70), Expect = 2.6
 Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 5/77 (6%)

Query: 413  SESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATIS 472
            S S   +P  +P+     ++P+V+  SE  +   P+ QP      R    P+  I A   
Sbjct: 4332 SSSARTKPTSLPISQSRGRIPIVAQNSEEESPLSPVGQPMGMA--RAAAGPLPPISAD-- 4387

Query: 473  LNTDQTTASSSLPAASQ 489
               DQ  +S SLP   Q
Sbjct: 4388 -TRDQFGSSHSLPEVQQ 4403



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 45/217 (20%), Positives = 83/217 (38%), Gaps = 13/217 (5%)

Query: 260  EEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQF----TSGEKEQVDE 315
            ++   APA E   P+AE  P  + TE  +       ++   AE Q     T  EK    E
Sbjct: 997  KKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPE 1056

Query: 316  WTVETVEV-VNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQ 374
             T    +  +N   + P   +      + +  +   +P      +Q+ +         I 
Sbjct: 1057 STCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAIS 1116

Query: 375  DSMLDFENQTLDPAIVSAQPMN-PTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVP 433
              + D       P+   A PM  PT++      V P V    +L +  +  V+ EA +V 
Sbjct: 1117 GQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQV----KLVKKQEQEVKTEAEKV- 1171

Query: 434  LVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQAT 470
            ++    E  T S     P   T+Q+ ++  +++ +A+
Sbjct: 1172 ILEKVKE--TLSMEKIPPMVTTDQKQEESKLEKDKAS 1206


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 67/272 (24%), Positives = 108/272 (39%), Gaps = 36/272 (13%)

Query: 330 QPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAI 389
           QPQA  P+ P PH  T + QA  L  ++           P+  +Q  +     Q   P+ 
Sbjct: 233 QPQA--PTAPVPH--THIQQAPALHPQRPPSPHPPPHPSPHPPLQP-LTGSAGQPSAPS- 286

Query: 390 VSAQPMNPTQNMDMPQ-LVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQ-- 446
             AQP    Q    P  L   P+       QP  +P Q    Q PL +S +  Y  +   
Sbjct: 287 -HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 345

Query: 447 -PLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSG 505
            P  Q +  ++Q P+++P+    A +++   +   ++ +P    PQ  +     P H SG
Sbjct: 346 LPASQSALQSQQPPREQPLPP--APLAMPHIKPPPTTPIPQLPAPQAHK----HPPHLSG 399

Query: 506 -----INVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTE 560
                +N N  P  +++ + +++   PP   P  L+   Q Q     S  +QP  + Q++
Sbjct: 400 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL--PSSPAQPPGLTQSQ 457

Query: 561 LQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQ 592
                           P  SH  TG HQ  PQ
Sbjct: 458 NLPP------------PPASHPPTGLHQVAPQ 477



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 77/317 (24%), Positives = 117/317 (36%), Gaps = 52/317 (16%)

Query: 260 EEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTS-GEKEQVDEWTV 318
           +E AS+P   ++    + E     TE+++  S++    Q ++     S GE E  D  +V
Sbjct: 83  KEEASSPLKSNK---RQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 139

Query: 319 --ETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDS 376
             E       + Q  ++ SPS+P P      + +D   ++Q +Q     +Q P       
Sbjct: 140 NDEGSSDPKDIDQDNRSTSPSIPSPQDNE--SDSDSSAQQQMLQAQPPALQAPTG----- 192

Query: 377 MLDFENQTLDPAIVSAQPMNP---TQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVP 433
                   + PA  SA P  P   T          PP  S +     +Q P QP+A   P
Sbjct: 193 --------VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA----SQAPNQPQAPTAP 240

Query: 434 LVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVF 493
           +  +  +   A  P   PS      P   P  Q           +    S P+ +QP   
Sbjct: 241 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQ-------PLTGSAGQPSAPSHAQP--- 290

Query: 494 QAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETL-KQQNQYQASYNQS-FSS 551
                 PLH  G      P  S+Q    +  P PP  +P  L  Q +Q QA    S  ++
Sbjct: 291 ------PLHGQG---PPGP-HSLQAGPLLQHPGPP--QPFGLPPQASQGQAPLGTSPAAA 338

Query: 552 QPHQVEQTELQQEQLQT 568
            PH   Q    Q  LQ+
Sbjct: 339 YPHTSLQLPASQSALQS 355


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 67/272 (24%), Positives = 108/272 (39%), Gaps = 36/272 (13%)

Query: 330  QPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAI 389
            QPQA  P+ P PH  T + QA  L  ++           P+  +Q  +     Q   P+ 
Sbjct: 787  QPQA--PTAPVPH--THIQQAPALHPQRPPSPHPPPHPSPHPPLQP-LTGSAGQPSAPS- 840

Query: 390  VSAQPMNPTQNMDMPQ-LVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQ-- 446
              AQP    Q    P  L   P+       QP  +P Q    Q PL +S +  Y  +   
Sbjct: 841  -HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899

Query: 447  -PLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSG 505
             P  Q +  ++Q P+++P+    A +++   +   ++ +P    PQ  +     P H SG
Sbjct: 900  LPASQSALQSQQPPREQPLPP--APLAMPHIKPPPTTPIPQLPAPQAHK----HPPHLSG 953

Query: 506  -----INVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTE 560
                 +N N  P  +++ + +++   PP   P  L+   Q Q     S  +QP  + Q++
Sbjct: 954  PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL--PSSPAQPPGLTQSQ 1011

Query: 561  LQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQ 592
                            P  SH  TG HQ  PQ
Sbjct: 1012 NLPP------------PPASHPPTGLHQVAPQ 1031



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 77/317 (24%), Positives = 117/317 (36%), Gaps = 52/317 (16%)

Query: 260 EEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTS-GEKEQVDEWTV 318
           +E AS+P   ++    + E     TE+++  S++    Q ++     S GE E  D  +V
Sbjct: 637 KEEASSPLKSNK---RQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 693

Query: 319 --ETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDS 376
             E       + Q  ++ SPS+P P      + +D   ++Q +Q     +Q P       
Sbjct: 694 NDEGSSDPKDIDQDNRSTSPSIPSPQDNE--SDSDSSAQQQMLQAQPPALQAPTG----- 746

Query: 377 MLDFENQTLDPAIVSAQPMNP---TQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVP 433
                   + PA  SA P  P   T          PP  S +     +Q P QP+A   P
Sbjct: 747 --------VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA----SQAPNQPQAPTAP 794

Query: 434 LVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVF 493
           +  +  +   A  P   PS      P   P  Q           +    S P+ +QP   
Sbjct: 795 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQ-------PLTGSAGQPSAPSHAQP--- 844

Query: 494 QAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETL-KQQNQYQASYNQS-FSS 551
                 PLH  G      P  S+Q    +  P PP  +P  L  Q +Q QA    S  ++
Sbjct: 845 ------PLHGQG---PPGP-HSLQAGPLLQHPGPP--QPFGLPPQASQGQAPLGTSPAAA 892

Query: 552 QPHQVEQTELQQEQLQT 568
            PH   Q    Q  LQ+
Sbjct: 893 YPHTSLQLPASQSALQS 909


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 67/272 (24%), Positives = 108/272 (39%), Gaps = 36/272 (13%)

Query: 330  QPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAI 389
            QPQA  P+ P PH  T + QA  L  ++           P+  +Q  +     Q   P+ 
Sbjct: 787  QPQA--PTAPVPH--THIQQAPALHPQRPPSPHPPPHPSPHPPLQP-LTGSAGQPSAPS- 840

Query: 390  VSAQPMNPTQNMDMPQ-LVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQ-- 446
              AQP    Q    P  L   P+       QP  +P Q    Q PL +S +  Y  +   
Sbjct: 841  -HAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQ 899

Query: 447  -PLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSG 505
             P  Q +  ++Q P+++P+    A +++   +   ++ +P    PQ  +     P H SG
Sbjct: 900  LPASQSALQSQQPPREQPLPP--APLAMPHIKPPPTTPIPQLPAPQAHK----HPPHLSG 953

Query: 506  -----INVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTE 560
                 +N N  P  +++ + +++   PP   P  L+   Q Q     S  +QP  + Q++
Sbjct: 954  PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPL--PSSPAQPPGLTQSQ 1011

Query: 561  LQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQ 592
                            P  SH  TG HQ  PQ
Sbjct: 1012 NLPP------------PPASHPPTGLHQVAPQ 1031



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 77/317 (24%), Positives = 117/317 (36%), Gaps = 52/317 (16%)

Query: 260 EEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTS-GEKEQVDEWTV 318
           +E AS+P   ++    + E     TE+++  S++    Q ++     S GE E  D  +V
Sbjct: 637 KEEASSPLKSNK---RQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 693

Query: 319 --ETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDS 376
             E       + Q  ++ SPS+P P      + +D   ++Q +Q     +Q P       
Sbjct: 694 NDEGSSDPKDIDQDNRSTSPSIPSPQDNE--SDSDSSAQQQMLQAQPPALQAPTG----- 746

Query: 377 MLDFENQTLDPAIVSAQPMNP---TQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVP 433
                   + PA  SA P  P   T          PP  S +     +Q P QP+A   P
Sbjct: 747 --------VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTA----SQAPNQPQAPTAP 794

Query: 434 LVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVF 493
           +  +  +   A  P   PS      P   P  Q           +    S P+ +QP   
Sbjct: 795 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQ-------PLTGSAGQPSAPSHAQP--- 844

Query: 494 QAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETL-KQQNQYQASYNQS-FSS 551
                 PLH  G      P  S+Q    +  P PP  +P  L  Q +Q QA    S  ++
Sbjct: 845 ------PLHGQG---PPGP-HSLQAGPLLQHPGPP--QPFGLPPQASQGQAPLGTSPAAA 892

Query: 552 QPHQVEQTELQQEQLQT 568
            PH   Q    Q  LQ+
Sbjct: 893 YPHTSLQLPASQSALQS 909


>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
           sapiens]
          Length = 898

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 47/169 (27%), Positives = 63/169 (37%), Gaps = 21/169 (12%)

Query: 521 NMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTV-------VGTY 573
           N N+PVPP +  +      Q + SY   + S  HQ +Q    Q              G  
Sbjct: 725 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQS--HQGQQQSYNQSPYSNYGPPQGKQKGYN 782

Query: 574 HGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNSRGVSRGGSRGARGLM------NGYRG 627
           HG    S+  + N       +     S   Y  S G S G S G+ G         GY G
Sbjct: 783 HGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGG 842

Query: 628 PANG---FRGGYDGYRPSFSNTPNSGYTQSQFSAPRDYSGYQRDGYQQN 673
            + G   ++G   GY  S  N+P SG  Q+    P  Y   Q  GY +N
Sbjct: 843 GSGGGSSYQGKQGGYSQSNYNSPGSG--QNYSGPPSSYQSSQ-GGYGRN 888



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 10/98 (10%)

Query: 591 PQQNTGFPRSNQ--PYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPN 648
           P    G P  N+  P  N RG  RGGS   RG   G+ G  +G      GY  + +   +
Sbjct: 625 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHG------GYMNAGAGYGS 678

Query: 649 SGYTQSQFSAPRDYSGYQRDGYQQNFKRGSGQSGPRGA 686
            GY  +  SA   YS +  +G       G G  G  G+
Sbjct: 679 YGYGGN--SATAGYSQFYSNGGHSGNASGGGGGGGGGS 714


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 47/169 (27%), Positives = 63/169 (37%), Gaps = 21/169 (12%)

Query: 521 NMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTV-------VGTY 573
           N N+PVPP +  +      Q + SY   + S  HQ +Q    Q              G  
Sbjct: 721 NYNSPVPPKHAGKKQPHGGQQKPSYGSGYQS--HQGQQQSYNQSPYSNYGPPQGKQKGYN 778

Query: 574 HGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNSRGVSRGGSRGARGLM------NGYRG 627
           HG    S+  + N       +     S   Y  S G S G S G+ G         GY G
Sbjct: 779 HGQGSYSYSNSYNSPGGGGGSDYNYESKFNYSGSGGRSGGNSYGSGGASYNPGSHGGYGG 838

Query: 628 PANG---FRGGYDGYRPSFSNTPNSGYTQSQFSAPRDYSGYQRDGYQQN 673
            + G   ++G   GY  S  N+P SG  Q+    P  Y   Q  GY +N
Sbjct: 839 GSGGGSSYQGKQGGYSQSNYNSPGSG--QNYSGPPSSYQSSQ-GGYGRN 884



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 10/98 (10%)

Query: 591 PQQNTGFPRSNQ--PYYNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPN 648
           P    G P  N+  P  N RG  RGGS   RG   G+ G  +G      GY  + +   +
Sbjct: 621 PGFGMGGPMHNEVPPPPNLRGRGRGGSIRGRGRGRGFGGANHG------GYMNAGAGYGS 674

Query: 649 SGYTQSQFSAPRDYSGYQRDGYQQNFKRGSGQSGPRGA 686
            GY  +  SA   YS +  +G       G G  G  G+
Sbjct: 675 YGYGGN--SATAGYSQFYSNGGHSGNASGGGGGGGGGS 710


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 70/301 (23%), Positives = 114/301 (37%), Gaps = 44/301 (14%)

Query: 272 VPEAEPEPA-EEYTEQSEVESTEYVN--RQFMAETQFTSGEKEQVDEWTVETVEVVNSLQ 328
           +PEA P P     T  +   S+ +++   Q +A+ Q    + +Q+ +  ++ V   + L 
Sbjct: 27  LPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQ----QLQQMHQKQMQCVLQPHHLP 82

Query: 329 QQPQAASPSVP-------EPHSLTPVAQADPLVRRQRVQDLMAQM-----QGPYNFIQDS 376
             P    P +P       +P          P +  Q+ Q    QM      GP   +   
Sbjct: 83  PPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP-- 140

Query: 377 MLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVS 436
            ++ E+    P +     M P+Q+  MP    PP +     +QP   P QP  +Q P   
Sbjct: 141 -MELESPPESPPVPPGSYMPPSQSY-MPPPQPPPSYYPPTSSQPYLPPAQPSPSQSP--- 195

Query: 437 STSEGYTASQPLYQPSHATEQ---RPQKEPIDQIQATISLNTDQTTASSSL---PAASQP 490
             S+ Y A  P Y  S ++ Q      +  +   QA+ S  +   + S  L   P ++ P
Sbjct: 196 -PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPP 254

Query: 491 QVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFS 550
                   +PL S   N +    Q+        AP P   +P T+  Q Q Q  Y Q   
Sbjct: 255 GNKTTVQQEPLESGAKNKSTEQQQA--------APEP---DPSTMTPQEQQQYWYRQHLL 303

Query: 551 S 551
           S
Sbjct: 304 S 304


>gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2
           [Homo sapiens]
          Length = 387

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 52/207 (25%), Positives = 72/207 (34%), Gaps = 34/207 (16%)

Query: 498 SKPLHSSGINVNAAPFQSMQTVFNMNAPVP---PVNEPE------TLKQQNQYQAS---- 544
           S  + S G+     P   MQ   N   P P   P+  P       T    N   +S    
Sbjct: 101 SHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSM 160

Query: 545 --YNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGN---HQQPPQQNTGFPR 599
             YN S  S      Q ++   Q Q + G Y   P+ S Q       HQQPP Q    P+
Sbjct: 161 GGYNHSVPSSQSMPVQNQMTMSQGQPM-GNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQ 219

Query: 600 SNQPYYNSR--------GVSRGGSRGARGLMNGYR----GPANGFRGGYDGYRPSFSN-- 645
               +Y  +         V++G     +  +  YR    GP   + G  D Y   +S+  
Sbjct: 220 GGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGG 279

Query: 646 -TPNSGYTQSQFSAPRDYSGYQRDGYQ 671
             P  G  Q  +       G Q+D YQ
Sbjct: 280 QGPPEGMNQQYYPDGNSQYGQQQDAYQ 306


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 80/397 (20%), Positives = 142/397 (35%), Gaps = 33/397 (8%)

Query: 219  EGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPE 278
            EG E P      +   E VE + ++   D   +      E EEAA     + Q PE+E  
Sbjct: 1904 EGAEAPEAEKEAQPETESVEAL-ETEGEDEPESEGAEAQEAEEAAQEAEGQTQ-PESEVI 1961

Query: 279  PAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVETVEVVNSLQQQPQAASPSV 338
             ++E  E+++ ES +    +   ETQ   GE +   E  VE  E    +Q+  + A P  
Sbjct: 1962 ESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESE-DVEAPEAEGEMQEAEEEAQPE- 2019

Query: 339  PEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQ-PMNP 397
                  +   +A P    +  Q++  + Q      Q      E    +     A+  +  
Sbjct: 2020 ------SDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE 2073

Query: 398  TQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTASQPLYQPSHATEQ 457
             +    P+       SE   AQ  +   QPE+  V    +  E   A + +  P    E 
Sbjct: 2074 AEGEAHPE-------SEDVDAQEAEGEAQPESEGVEAPEAEGEAQKA-EGIEAPETEGEA 2125

Query: 458  RPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHSSGINVNAAPFQSMQ 517
            +P+ E I+  +A             + P +   +   A       S GI    A  ++  
Sbjct: 2126 QPESEGIEAPEA----------EGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQP 2175

Query: 518  TVFNMNAP-VPPVNEPET---LKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVVGTY 573
             +  + AP      +PE+      + + +A         P   E+ + + E ++T     
Sbjct: 2176 ELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEG 2235

Query: 574  HGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYYNSRGV 610
               P+   +  G  +  PQ + G  +S +   +S  V
Sbjct: 2236 EAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPV 2272



 Score = 30.4 bits (67), Expect = 5.8
 Identities = 43/208 (20%), Positives = 70/208 (33%), Gaps = 28/208 (13%)

Query: 259  EEEAASAPAVEDQVPEAEPE--PAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVD-E 315
            E E   AP  E    EAE E  P  E  E  E E           E Q  S + E  + E
Sbjct: 1847 ESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAE----------GEAQPESEDVETPEAE 1896

Query: 316  WTVETVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQD 375
            W V+         +  + A P      +L    + +P       Q+            ++
Sbjct: 1897 WEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQE-----------AEE 1945

Query: 376  SMLDFENQTL-DPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPL 434
            +  + E QT  +  ++ +Q        +   +    V  E++ A+      QPE+  V  
Sbjct: 1946 AAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE---AQPESEDVEA 2002

Query: 435  VSSTSEGYTASQPLYQPSHATEQRPQKE 462
              +  E   A +     S   E +P+ E
Sbjct: 2003 PEAEGEMQEAEEEAQPESDGVEAQPKSE 2030


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 59/266 (22%), Positives = 119/266 (44%), Gaps = 27/266 (10%)

Query: 56   QILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRS 115
            ++L V +K+ + ++  K ++   +E +   +     QL   SK QE+ N L+  +E   +
Sbjct: 820  ELLKVANKE-KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNT 878

Query: 116  FMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGD----DEVRTDLKQG 171
              A+ ++ +K +  T +  Q ++EE E  +       Q+ L +       +E+   LK+ 
Sbjct: 879  MKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK 938

Query: 172  LNGV----PILSEEELSLLDEFYKLVDPERDMSL------RLNEQ-YEHASI-----HLW 215
             N +     +L E E  L  +   L D + +  L      +L +Q Y+ AS       L 
Sbjct: 939  ENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELL 998

Query: 216  DLLEGKEKPVCGTTYKV--LKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVP 273
             ++  +EK + G   ++  LK+ VE   + N   +    +N    E  A++   ++D+V 
Sbjct: 999  KVISEREKEISGLWNELDSLKDAVEHQRKKN---NDLREKNWEAMEALASTEKMLQDKVN 1055

Query: 274  EAEPEPAEEYTEQSEVESTEYVNRQF 299
            +   E  ++  E  E+E+ E + + F
Sbjct: 1056 KTSKE-RQQQVEAVELEAKEVLKKLF 1080


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 59/266 (22%), Positives = 119/266 (44%), Gaps = 27/266 (10%)

Query: 56   QILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRS 115
            ++L V +K+ + ++  K ++   +E +   +     QL   SK QE+ N L+  +E   +
Sbjct: 820  ELLKVANKE-KTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNT 878

Query: 116  FMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGD----DEVRTDLKQG 171
              A+ ++ +K +  T +  Q ++EE E  +       Q+ L +       +E+   LK+ 
Sbjct: 879  MKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK 938

Query: 172  LNGV----PILSEEELSLLDEFYKLVDPERDMSL------RLNEQ-YEHASI-----HLW 215
             N +     +L E E  L  +   L D + +  L      +L +Q Y+ AS       L 
Sbjct: 939  ENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELL 998

Query: 216  DLLEGKEKPVCGTTYKV--LKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVP 273
             ++  +EK + G   ++  LK+ VE   + N   +    +N    E  A++   ++D+V 
Sbjct: 999  KVISEREKEISGLWNELDSLKDAVEHQRKKN---NDLREKNWEAMEALASTEKMLQDKVN 1055

Query: 274  EAEPEPAEEYTEQSEVESTEYVNRQF 299
            +   E  ++  E  E+E+ E + + F
Sbjct: 1056 KTSKE-RQQQVEAVELEAKEVLKKLF 1080


>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
          Length = 1069

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 39/153 (25%), Positives = 78/153 (50%), Gaps = 5/153 (3%)

Query: 55   KQILGVIDKKLRNLEKKKGKLDDYQER-MNKGERLNQDQLDAVSKYQEVTNNLEFAKELQ 113
            KQ L   +++ R LE++  +L +   R ++K E   +     +  Y+++ + L  ++ L+
Sbjct: 892  KQKLIDAEEEKRRLEEESAQLKEMCRRELDKAESEIKKNSSIIGDYKQICSQL--SERLE 949

Query: 114  RSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLN 173
            +   A   +I+K  +K    E+      ++ R+K +   + VLD+  D+E  T LK  L 
Sbjct: 950  KQQTANKVEIEKIRQKVDDCERCREFFNKEGRVKGISSTKEVLDEDTDEEKET-LKNQLR 1008

Query: 174  GVPI-LSEEELSLLDEFYKLVDPERDMSLRLNE 205
             + + L++ +L L++   K+ D E  + L LNE
Sbjct: 1009 EMELELAQTKLQLVEAECKIQDLEHHLGLALNE 1041


>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
          Length = 1075

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 87/348 (25%), Positives = 120/348 (34%), Gaps = 52/348 (14%)

Query: 338  VPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNP 397
            +P+ H + P  QA P +    V + +   QG Y   + S+    +    PA  SA PM  
Sbjct: 714  IPQIH-MGPAVQA-PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPA--SAPPMMQ 769

Query: 398  TQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQ-----------VPLVSSTSEGYTA-S 445
                  P LV    +S      P Q P QP   Q            P++ S     T+ S
Sbjct: 770  AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGS 829

Query: 446  QPLYQPSHATEQRPQKE-PIDQ-IQATI---------SLNTDQTTASSSLPAASQPQVFQ 494
             P    S +T Q P  E P  Q + AT+          L+  Q   +++ P  SQPQ   
Sbjct: 830  HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATT-PTGSQPQSQH 888

Query: 495  AGTSKPLHSSGINVNAAPFQSMQTVFNMNA--PVPPVNEPETLKQQNQYQ-----ASYNQ 547
            A  S   H +G   +    Q  Q +++  A    PP   P    Q  Q       A Y  
Sbjct: 889  AAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAI 948

Query: 548  SFSSQPHQ-VEQTELQQEQLQT-VVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRSNQPYY 605
                 PH       + Q  +QT +       P   H        PPQ + G P+   P  
Sbjct: 949  HHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQS 1008

Query: 606  NSRGVSR---------GGSRGARGLMNGYRGPANGFRGGYDGYRPSFS 644
                +S          G  +G +       G A GF GG D     FS
Sbjct: 1009 GVPALSASTPSPYPYIGHPQGEQ------PGQAPGFPGGADDRIREFS 1050


>gi|56117846 synovial sarcoma translocation, chromosome 18 isoform 1
           [Homo sapiens]
          Length = 418

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 56/227 (24%), Positives = 79/227 (34%), Gaps = 35/227 (15%)

Query: 498 SKPLHSSGINVNAAPFQSMQTVFNMNAPVP---PVNEPE------TLKQQNQYQAS---- 544
           S  + S G+     P   MQ   N   P P   P+  P       T    N   +S    
Sbjct: 101 SHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQLNMTNSSMNMPSSSHGSM 160

Query: 545 --YNQSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGN---HQQPPQQNTGFPR 599
             YN S  S      Q ++   Q Q + G Y   P+ S Q       HQQPP Q    P+
Sbjct: 161 GGYNHSVPSSQSMPVQNQMTMSQGQPM-GNYGPRPNMSMQPNQGPMMHQQPPSQQYNMPQ 219

Query: 600 SNQPYYNSR--------GVSRGGSRGARGLMNGYR----GPANGFRGGYDGYRPSFSN-- 645
               +Y  +         V++G     +  +  YR    GP   + G  D Y   +S+  
Sbjct: 220 GGGQHYQGQQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGG 279

Query: 646 -TPNSGYTQSQFSAPRDYSGYQRDGY-QQNFKRGSGQSGPRGAPRGN 690
             P  G  Q  +    +  GYQ+  Y +Q + R    S       GN
Sbjct: 280 QGPPEGMNQQYYPDGHNDYGYQQPSYPEQGYDRPYEDSSQHYYEGGN 326


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 61/282 (21%), Positives = 103/282 (36%), Gaps = 52/282 (18%)

Query: 260 EEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVE 319
           E+   +P V        P+PA +Y              QF+ E +    E+E+ +E   E
Sbjct: 2   EDLDQSPLVSSSDSPPRPQPAFKY--------------QFVREPEDEEEEEEEEEEDEDE 47

Query: 320 TVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLD 379
            +E +  L+++P A   + P P   T  A   PL                        +D
Sbjct: 48  DLEELEVLERKPAAGLSAAPVP---TAPAAGAPL------------------------MD 80

Query: 380 FENQTLDPA----IVSAQPMNPTQNMDM-PQLVCPPVHSESRLA----QPNQVPVQPEAT 430
           F N  + PA    + +A P+ P +     P  V   V + S L+     P+++P   E  
Sbjct: 81  FGNDFVPPAPRGPLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPP 140

Query: 431 QVPLVSSTSEGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQP 490
             P     +     ++P++ P       P   P    +   S + D+T    +LPAAS+P
Sbjct: 141 ARPPPPPPASVSPQAEPVWTPPAPAPAAPPSTPAAPKRRGSSGSVDETL--FALPAASEP 198

Query: 491 QVFQAGTSKPLHSSGINVNAAPFQSMQTVFNMNAPVPPVNEP 532
            +  +  +  L     N  +A  +   +V    A   P   P
Sbjct: 199 VIRSSAENMDLKEQPGNTISAGQEDFPSVLLETAASLPSLSP 240


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 66/269 (24%), Positives = 93/269 (34%), Gaps = 27/269 (10%)

Query: 354  VRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHS 413
            +R+Q++Q  + Q Q     +         Q   P+  SA P  PTQ    PQ   PP   
Sbjct: 1812 LRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPP--- 1868

Query: 414  ESRLAQPNQVPVQPEATQVPLVSST------SEGYTASQ------PLYQPSHATEQRPQK 461
                AQP   PV       P V+ T      S G   SQ      P   P  A E   Q 
Sbjct: 1869 ----AQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQI 1924

Query: 462  EPIDQIQA---TISLNTDQTTASSSL-PAASQPQVFQAGTSKPLHSSG-INVNAAPFQSM 516
            E   Q Q     +++N       + +    SQ         +P   SG +  +  P Q  
Sbjct: 1925 EREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQ 1984

Query: 517  QTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGS 576
            Q       P+P +  P  +  Q Q   +  +  S QP +       Q+ L+T+      S
Sbjct: 1985 QAPLPQQQPMPGLPRP-VISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSP--SS 2041

Query: 577  PDQSHQVTGNHQQPPQQNTGFPRSNQPYY 605
            P Q  QV    +  PQ    F +     Y
Sbjct: 2042 PQQQQQVLNILKSNPQLMAAFIKQRTAKY 2070



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 60/280 (21%), Positives = 105/280 (37%), Gaps = 35/280 (12%)

Query: 330  QPQAASPSVPEPHSLT-PVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTL--D 386
            Q    S +VP P+ ++ PV  + P  + Q+        Q P   +   ++  + Q     
Sbjct: 1956 QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAP---LPQQQPMPGLPRPVISMQAQAAVAG 2012

Query: 387  PAIVSAQP---MNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYT 443
            P + S QP   ++P+   D+ + +  P   + +    N +   P+     +   T++ Y 
Sbjct: 2013 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK-YV 2071

Query: 444  ASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHS 503
            A+QP  QP    + +P  +P   +    SL  +     + +P    P   QA        
Sbjct: 2072 ANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQ-NLNAMQAGVPRPGVPPQQQA-------M 2123

Query: 504  SGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQ 563
             G+N        M           P + P       QY+    +    Q  Q +Q + QQ
Sbjct: 2124 GGLNPQGQALNIMN----------PGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQ 2173

Query: 564  EQLQTVVGTYHGSPDQSHQVTGNHQ-QPPQQNTGFPRSNQ 602
            +Q Q       GS   +  + G+ Q Q PQ   G+P + Q
Sbjct: 2174 QQQQ------QGSAGMAGGMAGHGQFQQPQGPGGYPPAMQ 2207



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 43/230 (18%), Positives = 78/230 (33%), Gaps = 21/230 (9%)

Query: 262  AASAPAVEDQVPEA--EPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVE 319
            AA  P+++   P     P+PA      + V S+          T             +  
Sbjct: 825  AAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSG------QTPTPTPGSVPSATQTQSTP 878

Query: 320  TVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLD 379
            TV+     Q  PQ  +P  P P   TP        +  + Q      Q P   +  +   
Sbjct: 879  TVQAAAQAQVTPQPQTPVQP-PSVATP--------QSSQQQPTPVHAQPPGTPLSQAAAS 929

Query: 380  FENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTS 439
             +N+   P+ V++   N  Q    P    P +  ++     +  P   E+   P      
Sbjct: 930  IDNRVPTPSSVASAETNSQQ----PGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMME 985

Query: 440  EGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQ 489
            E    +  + + +   EQ+ +   +D+ +  + +   +   SSS   ASQ
Sbjct: 986  EDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQ 1035


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 66/269 (24%), Positives = 93/269 (34%), Gaps = 27/269 (10%)

Query: 354  VRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHS 413
            +R+Q++Q  + Q Q     +         Q   P+  SA P  PTQ    PQ   PP   
Sbjct: 1850 LRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPP--- 1906

Query: 414  ESRLAQPNQVPVQPEATQVPLVSST------SEGYTASQ------PLYQPSHATEQRPQK 461
                AQP   PV       P V+ T      S G   SQ      P   P  A E   Q 
Sbjct: 1907 ----AQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQI 1962

Query: 462  EPIDQIQA---TISLNTDQTTASSSL-PAASQPQVFQAGTSKPLHSSG-INVNAAPFQSM 516
            E   Q Q     +++N       + +    SQ         +P   SG +  +  P Q  
Sbjct: 1963 EREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQ 2022

Query: 517  QTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQEQLQTVVGTYHGS 576
            Q       P+P +  P  +  Q Q   +  +  S QP +       Q+ L+T+      S
Sbjct: 2023 QAPLPQQQPMPGLPRP-VISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSP--SS 2079

Query: 577  PDQSHQVTGNHQQPPQQNTGFPRSNQPYY 605
            P Q  QV    +  PQ    F +     Y
Sbjct: 2080 PQQQQQVLNILKSNPQLMAAFIKQRTAKY 2108



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 60/280 (21%), Positives = 105/280 (37%), Gaps = 35/280 (12%)

Query: 330  QPQAASPSVPEPHSLT-PVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTL--D 386
            Q    S +VP P+ ++ PV  + P  + Q+        Q P   +   ++  + Q     
Sbjct: 1994 QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAP---LPQQQPMPGLPRPVISMQAQAAVAG 2050

Query: 387  PAIVSAQP---MNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYT 443
            P + S QP   ++P+   D+ + +  P   + +    N +   P+     +   T++ Y 
Sbjct: 2051 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK-YV 2109

Query: 444  ASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQPQVFQAGTSKPLHS 503
            A+QP  QP    + +P  +P   +    SL  +     + +P    P   QA        
Sbjct: 2110 ANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQ-NLNAMQAGVPRPGVPPQQQA-------M 2161

Query: 504  SGINVNAAPFQSMQTVFNMNAPVPPVNEPETLKQQNQYQASYNQSFSSQPHQVEQTELQQ 563
             G+N        M           P + P       QY+    +    Q  Q +Q + QQ
Sbjct: 2162 GGLNPQGQALNIMN----------PGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQ 2211

Query: 564  EQLQTVVGTYHGSPDQSHQVTGNHQ-QPPQQNTGFPRSNQ 602
            +Q Q       GS   +  + G+ Q Q PQ   G+P + Q
Sbjct: 2212 QQQQ------QGSAGMAGGMAGHGQFQQPQGPGGYPPAMQ 2245



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 43/230 (18%), Positives = 78/230 (33%), Gaps = 21/230 (9%)

Query: 262  AASAPAVEDQVPEA--EPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVE 319
            AA  P+++   P     P+PA      + V S+          T             +  
Sbjct: 863  AAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSG------QTPTPTPGSVPSATQTQSTP 916

Query: 320  TVEVVNSLQQQPQAASPSVPEPHSLTPVAQADPLVRRQRVQDLMAQMQGPYNFIQDSMLD 379
            TV+     Q  PQ  +P  P P   TP        +  + Q      Q P   +  +   
Sbjct: 917  TVQAAAQAQVTPQPQTPVQP-PSVATP--------QSSQQQPTPVHAQPPGTPLSQAAAS 967

Query: 380  FENQTLDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTS 439
             +N+   P+ V++   N  Q    P    P +  ++     +  P   E+   P      
Sbjct: 968  IDNRVPTPSSVASAETNSQQ----PGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMME 1023

Query: 440  EGYTASQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASSSLPAASQ 489
            E    +  + + +   EQ+ +   +D+ +  + +   +   SSS   ASQ
Sbjct: 1024 EDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQ 1073


>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
           [Homo sapiens]
          Length = 806

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 32/163 (19%)

Query: 555 QVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQ--QNTGFPRSNQPYYNSRGVSR 612
           ++   ELQ+E+ Q ++  Y     ++         PP+  QNTG  +SN+        +R
Sbjct: 632 EITYVELQKEEAQKLLEQYKEESKKA--------LPPEKKQNTGSKKSNKNKSGKNQFNR 683

Query: 613 GGSRGARGLMN----GYRGPANGFRGGYD--GYRP----SFSNTPNSGYTQSQ---FSAP 659
           GG    RG  N     +RG A G RGGY+  G  P        +   GY   +   F   
Sbjct: 684 GGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 743

Query: 660 RDYS---GYQRDG------YQQNFKRGSGQSGPRGAPRGNILW 693
             YS    Y R G      Y QNF+      G +   +G   W
Sbjct: 744 GSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQW 786


>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
           [Homo sapiens]
          Length = 825

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 32/163 (19%)

Query: 555 QVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQ--QNTGFPRSNQPYYNSRGVSR 612
           ++   ELQ+E+ Q ++  Y     ++         PP+  QNTG  +SN+        +R
Sbjct: 651 EITYVELQKEEAQKLLEQYKEESKKA--------LPPEKKQNTGSKKSNKNKSGKNQFNR 702

Query: 613 GGSRGARGLMN----GYRGPANGFRGGYD--GYRP----SFSNTPNSGYTQSQ---FSAP 659
           GG    RG  N     +RG A G RGGY+  G  P        +   GY   +   F   
Sbjct: 703 GGGHRGRGGFNMRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPGR 762

Query: 660 RDYS---GYQRDG------YQQNFKRGSGQSGPRGAPRGNILW 693
             YS    Y R G      Y QNF+      G +   +G   W
Sbjct: 763 GSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRGYKNQSQGYNQW 805


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 77/354 (21%), Positives = 118/354 (33%), Gaps = 39/354 (11%)

Query: 328 QQQPQAASPSVPEPHSLTPVAQADPLVRRQ---RVQDLMAQMQGPYNFIQDSMLDFENQT 384
           Q +PQA  PS P P +     QA P  ++    + Q L AQ Q      Q   L  + Q 
Sbjct: 417 QPKPQAP-PSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQ 475

Query: 385 LDPAIVSAQPMNPTQNMDMPQLVCPPVHSESRLAQPNQVPVQPEATQVPLVSSTSEGYTA 444
             P     QP          Q          +    +    QP   Q P+VS        
Sbjct: 476 QQPPPAQQQPAGTFYQQQQAQT--------QQFQAVHPATQQPAIAQFPVVSQGGSQQQL 527

Query: 445 SQPLYQPSHATEQRPQKEPIDQIQATISLNTDQTTASS--SLPAASQPQVFQAGTSKPLH 502
            Q  YQ     +Q+ Q++ +        L T Q       ++ A  QPQ   A   +P  
Sbjct: 528 MQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQPAP 587

Query: 503 SSGINVNAAPFQSMQTVFNMNAP---------VPPVNEPETLKQQNQ-------YQASYN 546
           +    +  AP +    V     P         + P + P+T +  ++       + A + 
Sbjct: 588 AQEPAIQ-APVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAVFG 646

Query: 547 --QSFSSQPHQVEQTELQQEQLQTVVGTYHGSPDQSHQVTGNHQQPPQQNTGFPRSNQPY 604
              S S+Q  Q    E    + ++   T  GSP  S Q   N   P + +T  P  +  +
Sbjct: 647 VPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQ---NVYNPSEGSTWNPFDDDNF 703

Query: 605 YNSRGVSRGGSRGARGLMNGYRGPANGFRGGYDGYRPSFSNTPNSGYTQSQFSA 658
                        A+ L  G      G  G  +   P F +T    +  + FSA
Sbjct: 704 SKLTAEELLNKDFAK-LGEGKHPEKLG--GSAESLIPGFQSTQGDAFATTSFSA 754


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.125    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,509,550
Number of Sequences: 37866
Number of extensions: 1530083
Number of successful extensions: 12955
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 110
Number of HSP's successfully gapped in prelim test: 638
Number of HSP's that attempted gapping in prelim test: 10881
Number of HSP's gapped (non-prelim): 2438
length of query: 694
length of database: 18,247,518
effective HSP length: 109
effective length of query: 585
effective length of database: 14,120,124
effective search space: 8260272540
effective search space used: 8260272540
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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