Search of human proteins with 42544241

Search of human proteins with 42544241

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42544241 iroquois homeobox protein 6 [Homo sapiens]
         (446 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42544241 iroquois homeobox protein 6 [Homo sapiens]                913   0.0  
gi|7705555 iroquois homeobox 4 [Homo sapiens]                         288   9e-78
gi|226371735 iroquois homeobox 3 [Homo sapiens]                       202   4e-52
gi|51479177 iroquois homeobox protein 1 [Homo sapiens]                197   2e-50
gi|197100900 iroquois homeobox 2 [Homo sapiens]                       177   2e-44
gi|39930475 iroquois homeobox 2 [Homo sapiens]                        177   2e-44
gi|139394646 iroquois homeobox protein 5 [Homo sapiens]               176   5e-44
gi|178057337 mohawk homeobox [Homo sapiens]                            81   2e-15
gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]                   68   2e-11
gi|89257348 homeo box HB9 [Homo sapiens]                               60   4e-09
gi|28178843 TG-interacting factor isoform a [Homo sapiens]             59   1e-08
gi|4507473 TG-interacting factor isoform c [Homo sapiens]              59   1e-08
gi|28178855 TG-interacting factor isoform d [Homo sapiens]             59   1e-08
gi|28178853 TG-interacting factor isoform d [Homo sapiens]             59   1e-08
gi|28178851 TG-interacting factor isoform d [Homo sapiens]             59   1e-08
gi|28178857 TG-interacting factor isoform d [Homo sapiens]             59   1e-08
gi|28178849 TG-interacting factor isoform c [Homo sapiens]             59   1e-08
gi|28178845 TG-interacting factor isoform b [Homo sapiens]             59   1e-08
gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]                    59   1e-08
gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]              57   3e-08
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          55   2e-07
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          55   2e-07
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          55   2e-07
gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo ...    54   2e-07
gi|57863279 Meis1, myeloid ecotropic viral integration site 1 ho...    54   3e-07
gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo ...    53   6e-07
gi|4505151 Meis homeobox 1 [Homo sapiens]                              52   8e-07
gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]                   52   8e-07
gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]                   52   8e-07
gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]                   52   8e-07

>gi|42544241 iroquois homeobox protein 6 [Homo sapiens]
          Length = 446

 Score =  913 bits (2359), Expect = 0.0
 Identities = 446/446 (100%), Positives = 446/446 (100%)

Query: 1   MSFPHFGHPYRGASQFLASASSSTTCCESTQRSVSDVASGSTPAPALCCAPYDSRLLGSA 60
           MSFPHFGHPYRGASQFLASASSSTTCCESTQRSVSDVASGSTPAPALCCAPYDSRLLGSA
Sbjct: 1   MSFPHFGHPYRGASQFLASASSSTTCCESTQRSVSDVASGSTPAPALCCAPYDSRLLGSA 60

Query: 61  RPELGAALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSSLAQ 120
           RPELGAALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSSLAQ
Sbjct: 61  RPELGAALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSSLAQ 120

Query: 121 PGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKI 180
           PGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKI
Sbjct: 121 PGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKI 180

Query: 181 MLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTK 240
           MLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTK
Sbjct: 181 MLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTK 240

Query: 241 EVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGPCAAAR 300
           EVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGPCAAAR
Sbjct: 241 EVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGPCAAAR 300

Query: 301 EGRLERRECGLAAPRFSFNDPSGSEEADFLSAETGSPRLTMHYPCLEKPRIWSLAHTATA 360
           EGRLERRECGLAAPRFSFNDPSGSEEADFLSAETGSPRLTMHYPCLEKPRIWSLAHTATA
Sbjct: 301 EGRLERRECGLAAPRFSFNDPSGSEEADFLSAETGSPRLTMHYPCLEKPRIWSLAHTATA 360

Query: 361 SAVEGAPPARPRPRSPECRMIPGQPPASARRLSVPRDSACDESSCIPKAFGNPKFALQGL 420
           SAVEGAPPARPRPRSPECRMIPGQPPASARRLSVPRDSACDESSCIPKAFGNPKFALQGL
Sbjct: 361 SAVEGAPPARPRPRSPECRMIPGQPPASARRLSVPRDSACDESSCIPKAFGNPKFALQGL 420

Query: 421 PLNCAPCPRRSEPVVQCQYPSGAEAG 446
           PLNCAPCPRRSEPVVQCQYPSGAEAG
Sbjct: 421 PLNCAPCPRRSEPVVQCQYPSGAEAG 446


>gi|7705555 iroquois homeobox 4 [Homo sapiens]
          Length = 519

 Score =  288 bits (736), Expect = 9e-78
 Identities = 194/440 (44%), Positives = 243/440 (55%), Gaps = 42/440 (9%)

Query: 1   MSFPHFGHPYRGASQFLASASSSTTCCESTQRSVSDVASGSTPAPALCCAPYDSRLLGSA 60
           MS+P FG+PY  A QFL + +S +TCCES  R+++D    ++    + C  Y+SRLL +A
Sbjct: 1   MSYPQFGYPYSSAPQFLMATNSLSTCCESGGRTLADSGPAASAQAPVYCPVYESRLLATA 60

Query: 61  RPELG--AALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSSL 118
           R EL   AALG+YG PY  +   Q Y  Y+ Y  E  + Y +LN  ++ K+ +GS    L
Sbjct: 61  RHELNSAAALGVYGGPYGGS---QGYGNYVTYGSEASAFY-SLN-SFDSKDGSGSAHGGL 115

Query: 119 AQPGA-YYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKG 177
           A   A YYPYE  LGQY Y+RYG ++ SG  RRKNATRETTSTLKAWL EHRKNPYPTKG
Sbjct: 116 APAAAAYYPYEPALGQYPYDRYGTMD-SGT-RRKNATRETTSTLKAWLQEHRKNPYPTKG 173

Query: 178 EKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERK-------AEGGEED 230
           EKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+NK  +E++        EGGEE+
Sbjct: 174 EKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWPPRNKCADEKRPYAEGEEEEGGEEE 233

Query: 231 SL-GCLTADTKEVTASQEARGLRLSDLEDLEEEEEEEEEAEDE----------EVVATAG 279
           +    L +        +E + L LSDL+D +  E E    E +          E V  A 
Sbjct: 234 AREEPLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGLERVPAAP 293

Query: 280 DRLTEFRKGA--QSLPGPCAAAREGRLER-RECGLAAPRFSFNDPSGSEEADFLSAETGS 336
           D   +   GA   SL     AA +  LER R C  +A       P          A+ G 
Sbjct: 294 DGPVKEASGALRMSLAAGGGAALDEDLERARSCLRSAAAGPEPLPGAEGGPQVCEAKLGF 353

Query: 337 PRLTMHYPCLEKPRIWSLAHTATASAVEGAPPARPRPRSPEC---RMIPGQP------PA 387
                      KPRIWSLAHTATA+A   A  +  +   P C   R  P  P      PA
Sbjct: 354 VPAGASAGLEAKPRIWSLAHTATAAA--AAATSLSQTEFPSCMLKRQGPAAPAAVSSAPA 411

Query: 388 SARRLSVPRDSACDESSCIP 407
           ++  +++P   A D     P
Sbjct: 412 TSPSVALPHSGALDRHQDSP 431


>gi|226371735 iroquois homeobox 3 [Homo sapiens]
          Length = 501

 Score =  202 bits (515), Expect = 4e-52
 Identities = 156/378 (41%), Positives = 192/378 (50%), Gaps = 81/378 (21%)

Query: 57  LGSARPELGAA-------LGIYGAPYAAAAAA---QSYPGYLPYSPEPPSLYGALNPQYE 106
           LG+   EL A+         +YGAPYAAAAAA   Q Y  +LPY+ E P ++  L  QYE
Sbjct: 36  LGAGASELNASGSLSNVLSSVYGAPYAAAAAAAAAQGYGAFLPYAAELP-IFPQLGAQYE 94

Query: 107 FKEAAG----SFTSSLAQPG-AYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTL 161
            K++ G    +  ++   P  A+YPY    GQYQ+            R KNATRE+TSTL
Sbjct: 95  LKDSPGVQHPAAAAAFPHPHPAFYPY----GQYQF--------GDPSRPKNATRESTSTL 142

Query: 162 KAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEE 221
           KAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAP+++  EE
Sbjct: 143 KAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEE 202

Query: 222 RKAEGGEEDSLGCLTADTKEVTASQEARGLRLSDLEDLEEEEEEE--------EEAEDEE 273
             A G E +         +E     E  G R  +LE+ E   EEE        ++ EDEE
Sbjct: 203 GNAYGSERE---------EEDEEEDEEDGKRELELEEEELGGEEEDTGGEGLADDDEDEE 253

Query: 274 VVATAGDRLTEFRKGAQSLPGPCAAAREGRLERRECGLAAPRFSFNDPSGSEEADF--LS 331
           +     D      +   SL G  AA R+G L       +    S +   G E+     LS
Sbjct: 254 IDLENLDGAA--TEPELSLAG--AARRDGDLGLGPISDSKNSDSEDSSEGLEDRPLPVLS 309

Query: 332 AETGSPRLTMHYP--------------------CLEKPRIWSLAHTATASAVEGAPPARP 371
                P + +  P                     L+KP+IWSLA TAT+       P  P
Sbjct: 310 LAPAPPPVAVASPSLPSPPVSLDPCAPAPAPASALQKPKIWSLAETATS-------PDNP 362

Query: 372 RPRSPECRMIPGQPPASA 389
           R   P      G PP +A
Sbjct: 363 RRSPPGA---GGSPPGAA 377


>gi|51479177 iroquois homeobox protein 1 [Homo sapiens]
          Length = 480

 Score =  197 bits (501), Expect = 2e-50
 Identities = 153/380 (40%), Positives = 195/380 (51%), Gaps = 51/380 (13%)

Query: 1   MSFPHFGHPYRGASQFLASASSSTTCCESTQRSVSDVASGSTPAPALCCAPYDSRLLGSA 60
           MSFP  G+P     Q+L++A          +R     A+ +  A A    P  + L G A
Sbjct: 1   MSFPQLGYP-----QYLSAAGPGAY---GGERPGVLAAAAAAAAAASSGRPGAAELGGGA 52

Query: 61  -RPELGAALGIYGA--PYAAAAAAQSYPGYLPYSPEPPSLYGALNPQYEFKEAAGSFTSS 117
               + + LG+Y A  PYA A    +Y  +LPY+ +  SL+  +  QYE K+  G   ++
Sbjct: 53  GAAAVTSVLGMYAAAGPYAGAP---NYSAFLPYAADL-SLFSQMGSQYELKDNPGVHPAT 108

Query: 118 LAQ--PGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPT 175
            A     AYYPY    GQ+QY           GR KNATRE+TSTLKAWLNEHRKNPYPT
Sbjct: 109 FAAHTAPAYYPY----GQFQY--------GDPGRPKNATRESTSTLKAWLNEHRKNPYPT 156

Query: 176 KGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCL 235
           KGEKIMLAIITKMTLTQVSTWFANARRRLKKENK+TW  ++K  E+    G +       
Sbjct: 157 KGEKIMLAIITKMTLTQVSTWFANARRRLKKENKVTWGARSKDQEDGALFGSD------- 209

Query: 236 TADTKEVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGP 295
           T    E     E   L   D++ ++E + ++   ED+E  A A          A+    P
Sbjct: 210 TEGDPEKAEDDEEIDLESIDIDKIDEHDGDQSN-EDDEDKAEAPHAPAAPSALARDQGSP 268

Query: 296 CAAAREGRLERRECGLA--APRFSFNDPSGSEEADFLSAETGSPRLTMHYPCLEKPRIWS 353
            AAA   + +    GLA  AP        GS       A  G  +   H     KP+IWS
Sbjct: 269 LAAADVLKPQDSPLGLAKEAPE------PGSTRLLSPGAAAGGLQGAPH----GKPKIWS 318

Query: 354 LAHTATASAVEGAPPARPRP 373
           LA TAT+   +GAP A P P
Sbjct: 319 LAETATSP--DGAPKASPPP 336


>gi|197100900 iroquois homeobox 2 [Homo sapiens]
          Length = 471

 Score =  177 bits (449), Expect = 2e-44
 Identities = 137/369 (37%), Positives = 176/369 (47%), Gaps = 42/369 (11%)

Query: 49  CAPYDSRLLGSARPELGAALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGA-LNPQYEF 107
           C  Y +  L + R E  A         A+ +A   YPG   ++ +  + +G+ L    + 
Sbjct: 20  CPAYGASALAAPRSEELARS-------ASGSAFSPYPGSAAFTAQAATGFGSPLQYSADA 72

Query: 108 KEAAGSFTSSLAQPGAYYPYERTLGQYQYERYGAV----ELSGAGRRKNATRETTSTLKA 163
             AA  F S +  P   +    T G   Y  YG+     +L+    RKNATR+ T+TLKA
Sbjct: 73  AAAAAGFPSYMGAPYDAHTTGMT-GAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKA 131

Query: 164 WLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERK 223
           WLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAP+NK  +E +
Sbjct: 132 WLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDE 191

Query: 224 AEGG---EEDSLGCLTADTKEVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGD 280
            EG     +D       +  E +A  E   L +  L D         E++ E++   AGD
Sbjct: 192 DEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTD----HSCSAESDGEKLPCRAGD 247

Query: 281 RLTEFRKGAQSLPGPCAAAREGRLERRECGLAAPRFSFNDPSGSEEADFLS--------- 331
            L E     +          +   E  E GLA P+   + P    EA  LS         
Sbjct: 248 PLCESGSECKDKYDDLEDDEDDD-EEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRG 306

Query: 332 ---AETGSPRLTMHYPCLEKPRIWSLAHTATASAVEGA------PPARPRPRSPECRMIP 382
                 GS       P   KP++WSLA  AT+   + +      PP  P   +P     P
Sbjct: 307 GRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAP 366

Query: 383 --GQP-PAS 388
             G P PAS
Sbjct: 367 PGGSPYPAS 375


>gi|39930475 iroquois homeobox 2 [Homo sapiens]
          Length = 471

 Score =  177 bits (449), Expect = 2e-44
 Identities = 137/369 (37%), Positives = 176/369 (47%), Gaps = 42/369 (11%)

Query: 49  CAPYDSRLLGSARPELGAALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGA-LNPQYEF 107
           C  Y +  L + R E  A         A+ +A   YPG   ++ +  + +G+ L    + 
Sbjct: 20  CPAYGASALAAPRSEELARS-------ASGSAFSPYPGSAAFTAQAATGFGSPLQYSADA 72

Query: 108 KEAAGSFTSSLAQPGAYYPYERTLGQYQYERYGAV----ELSGAGRRKNATRETTSTLKA 163
             AA  F S +  P   +    T G   Y  YG+     +L+    RKNATR+ T+TLKA
Sbjct: 73  AAAAAGFPSYMGAPYDAHTTGMT-GAISYHPYGSAAYPYQLNDPAYRKNATRDATATLKA 131

Query: 164 WLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERK 223
           WLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAP+NK  +E +
Sbjct: 132 WLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRNKSEDEDE 191

Query: 224 AEGG---EEDSLGCLTADTKEVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGD 280
            EG     +D       +  E +A  E   L +  L D         E++ E++   AGD
Sbjct: 192 DEGDATRSKDESPDKAQEGTETSAEDEGISLHVDSLTD----HSCSAESDGEKLPCRAGD 247

Query: 281 RLTEFRKGAQSLPGPCAAAREGRLERRECGLAAPRFSFNDPSGSEEADFLS--------- 331
            L E     +          +   E  E GLA P+   + P    EA  LS         
Sbjct: 248 PLCESGSECKDKYDDLEDDEDDD-EEGERGLAPPKPVTSSPLTGLEAPLLSPPPEAAPRG 306

Query: 332 ---AETGSPRLTMHYPCLEKPRIWSLAHTATASAVEGA------PPARPRPRSPECRMIP 382
                 GS       P   KP++WSLA  AT+   + +      PP  P   +P     P
Sbjct: 307 GRKTPQGSRTSPGAPPPASKPKLWSLAEIATSDLKQPSLGPGCGPPGLPAAAAPASTGAP 366

Query: 383 --GQP-PAS 388
             G P PAS
Sbjct: 367 PGGSPYPAS 375


>gi|139394646 iroquois homeobox protein 5 [Homo sapiens]
          Length = 483

 Score =  176 bits (445), Expect = 5e-44
 Identities = 147/431 (34%), Positives = 181/431 (41%), Gaps = 92/431 (21%)

Query: 49  CAPYDSRLLGSARPE------LGAALGIYGAPYAAAAAAQSYPGYLPYSPEPPSLYGALN 102
           C  Y + ++   R +       G+A   Y    A  A +  Y  +L Y  +P +   A  
Sbjct: 20  CPAYSTSVISGPRTDELGRSSSGSAFSPYAGSTAFTAPSPGYNSHLQYGADPAAAAAAA- 78

Query: 103 PQYEFKEAAGS---FTSSLAQPGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTS 159
               F    GS    T  +A    Y+PY   LG Y Y             RKNATR+ T+
Sbjct: 79  ----FSSYVGSPYDHTPGMAGSLGYHPYAAPLGSYPY--------GDPAYRKNATRDATA 126

Query: 160 TLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPKNKGG 219
           TLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTW P+N+  
Sbjct: 127 TLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSE 186

Query: 220 EERKAEGGEEDSLGCLTADTKEVTASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAG 279
           +E      EE+++                      DLE  +E+E ++ E + +     AG
Sbjct: 187 DEE-----EEENI----------------------DLEKNDEDEPQKPEDKGDPEGPEAG 219

Query: 280 DRLTEFRKGAQSLPGPCAAA---REGRLERRECGLAAPRFSFNDPSGSEEADFLSAETGS 336
               +   G + L GP   A    EG L   +         F +P      D L    G 
Sbjct: 220 GAEQKAASGCERLQGPPTPAGKETEGSLSDSD---------FKEPPSEGRLDALQ---GP 267

Query: 337 PRLTMHYPCLEKPRIWSLAHTATASAVEGAPPARPRPRSPECRMIPG-----------QP 385
           PR     P    P    LA         GAP   P P + E    PG            P
Sbjct: 268 PRTGGPSPA--GPAAARLAEDPAPHYPAGAPAPGPHPAAGEVPPGPGGPSVIHSPPPPPP 325

Query: 386 PA--------SARRLSVPRDSACD------ESSCIPKAFGNPKFALQGLPLNCAPCPRRS 431
           PA        S   ++   D   D       S C P        AL G   + AP P RS
Sbjct: 326 PAVLAKPKLWSLAEIATSSDKVKDGGGGNEGSPCPPCPGPIAGQALGGSRASPAPAPSRS 385

Query: 432 EPVVQCQYPSG 442
            P  QC +P G
Sbjct: 386 -PSAQCPFPGG 395


>gi|178057337 mohawk homeobox [Homo sapiens]
          Length = 352

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 46/96 (47%), Positives = 62/96 (64%), Gaps = 5/96 (5%)

Query: 126 PYERTLGQYQYERYGAVELSGAGRRKN-ATRETTSTLKAWLNEHRKNPYPTKGEKIMLAI 184
           P +  LG  ++ R GA +  G  R K  A ++    LK WL +HR NPYPTK EKI+LA+
Sbjct: 50  PLKDNLG-LRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLAL 108

Query: 185 ITKMTLTQVSTWFANARRRLK---KENKMTWAPKNK 217
            ++MTL QVS WFANARRRLK   ++  ++WA + K
Sbjct: 109 GSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIK 144


>gi|116812644 PBX/knotted 1 homeobox 2 [Homo sapiens]
          Length = 472

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 33/160 (20%)

Query: 155 RETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL---------- 204
           +  T+ +++WL +H  +PYPT+ EK  +A  T +TL QV+ WF NARRR+          
Sbjct: 297 KHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNP 356

Query: 205 ---------KKENKMT---WAPKNKGGEERKAEGGEE----------DSLGCLTADTKEV 242
                    K +++ T   W P +      + +GG            D+L  L++D+  +
Sbjct: 357 DPAPKAKKIKSQHRPTQRFW-PNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATM 415

Query: 243 TASQEARGLRLSDLEDLEEEEEEEEEAEDEEVVATAGDRL 282
              Q         L+  EEE+E+E E E+EE +    D L
Sbjct: 416 AMQQAMMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDEL 455


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 66/227 (29%), Positives = 94/227 (41%), Gaps = 31/227 (13%)

Query: 64  LGAALGIYGAP---YAAAAAAQSYPGYLP-YSPEPPSLYGA--LNPQYEFKEAAGSFTSS 117
           L A   +YG P   Y+AAAAA +  G  P  S   P + GA   +P    K  AG+F   
Sbjct: 152 LPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLD 211

Query: 118 ----LAQPGAYYPYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPY 173
                +  G   P         +       L G  RR   T  T+  L    ++ + N Y
Sbjct: 212 QWLRASTAGMILPK-----MPDFNSQAQSNLLGKCRRPR-TAFTSQQLLELEHQFKLNKY 265

Query: 174 PTKGEKIMLAIITKMTLTQVSTWFANARRRLK-----KENKMTWAPKNKGGEERKAEGGE 228
            ++ ++  +A    +T TQV  WF N R + K     KE     A K KGG     +GG 
Sbjct: 266 LSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGAGKGGA 325

Query: 229 EDSLGCLTADTKEV----TASQEARGLRLSDLEDLEEEEEEEEEAED 271
           E+         +E+        +  G RL DL D + EE+E+E+ ED
Sbjct: 326 EE------PGAEELLGPPAPGDKGSGRRLRDLRDSDPEEDEDEDDED 366


>gi|28178843 TG-interacting factor isoform a [Homo sapiens]
          Length = 401

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 160 AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 219

Query: 202 RRL 204
           RRL
Sbjct: 220 RRL 222



 Score = 30.8 bits (68), Expect = 2.6
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 21/110 (19%)

Query: 306 RRECGLAAPRFSFNDPSGSEEADFLSAETGSPRLTMHYPCLEKPRI------------WS 353
           R   G+ +P  S +   GS+   + ++  G+P+ +     L  PR+            WS
Sbjct: 7   RVSAGVGSPHCSGSGGGGSDSFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYLPPAPWS 66

Query: 354 LAHTATA----SAVEGAPPAR---PRPRSPECRMIPGQPPASARRLSVPR 396
              T +A    S     PPAR   PR  SPE     G  P    R  +PR
Sbjct: 67  SLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAG--PRRPHRWELPR 114


>gi|4507473 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 31  AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 90

Query: 202 RRL 204
           RRL
Sbjct: 91  RRL 93


>gi|28178855 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 11  AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 70

Query: 202 RRL 204
           RRL
Sbjct: 71  RRL 73


>gi|28178853 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 11  AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 70

Query: 202 RRL 204
           RRL
Sbjct: 71  RRL 73


>gi|28178851 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 11  AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 70

Query: 202 RRL 204
           RRL
Sbjct: 71  RRL 73


>gi|28178857 TG-interacting factor isoform d [Homo sapiens]
          Length = 252

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 11  AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 70

Query: 202 RRL 204
           RRL
Sbjct: 71  RRL 73


>gi|28178849 TG-interacting factor isoform c [Homo sapiens]
          Length = 272

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 31  AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 90

Query: 202 RRL 204
           RRL
Sbjct: 91  RRL 93


>gi|28178845 TG-interacting factor isoform b [Homo sapiens]
          Length = 286

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 28/63 (44%), Positives = 41/63 (65%), Gaps = 3/63 (4%)

Query: 145 SGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANAR 201
           +G+G+R+   N  +E+   L+ WL EHR N YP++ EK +L+  T ++  QV  WF NAR
Sbjct: 45  AGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINAR 104

Query: 202 RRL 204
           RRL
Sbjct: 105 RRL 107


>gi|28866955 PBX/knotted 1 homeobox 1 [Homo sapiens]
          Length = 436

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 7/111 (6%)

Query: 145 SGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR- 203
           S   +R    +  T+ +++WL +H  +PYPT+ EK  +A  T +TL QV+ WF NARRR 
Sbjct: 258 SSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRI 317

Query: 204 ----LKKENKMTWAPKNKGGEERKAEGGEEDSL--GCLTADTKEVTASQEA 248
               L      T   K K  + R  +    DS+  G       E+T S+ A
Sbjct: 318 LQPMLDSSCSETPKTKKKTAQNRPVQRFWPDSIASGVAQPPPSELTMSEGA 368


>gi|11141881 TGFB-induced factor homeobox 2 [Homo sapiens]
          Length = 237

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 29/64 (45%), Positives = 41/64 (64%), Gaps = 3/64 (4%)

Query: 144 LSGAGRRK---NATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANA 200
           LS AG+RK   N  +E+   L+ WL  HR N YP++ EK+ L+  T +++ Q+  WF NA
Sbjct: 13  LSLAGKRKRRGNLPKESVKILRDWLYLHRYNAYPSEQEKLSLSGQTNLSVLQICNWFINA 72

Query: 201 RRRL 204
           RRRL
Sbjct: 73  RRRL 76


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 27/231 (11%)

Query: 77   AAAAAQSYPGYLPYSPEPP--------SLYGALNPQYEFKEAAGSFTSS---LAQPGAYY 125
            AA   +SY    P   EPP        S    L P +   E     T +    ++ G ++
Sbjct: 1734 AAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHW 1793

Query: 126  PYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAII 185
            P E    + +  R     L  AGRR + T+ T    +A  +    + YP  GE   LA +
Sbjct: 1794 PIE----EEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASL 1849

Query: 186  TKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTKEVTAS 245
              +    V  WF NAR++ +K          +GG      GG   + GC           
Sbjct: 1850 LGLASRVVVVWFQNARQKARKN-------ACEGG-SMPTGGGTGGASGCRRCHATFSCVF 1901

Query: 246  QEARGL-RLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGP 295
            +  R L +  D + LEEEEEE E  E+EE V    +   E  +G +   GP
Sbjct: 1902 ELVRHLKKCYDDQTLEEEEEEAERGEEEEEVE---EEEVEEEQGLEPPAGP 1949


>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 27/231 (11%)

Query: 77   AAAAAQSYPGYLPYSPEPP--------SLYGALNPQYEFKEAAGSFTSS---LAQPGAYY 125
            AA   +SY    P   EPP        S    L P +   E     T +    ++ G ++
Sbjct: 1650 AAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHW 1709

Query: 126  PYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAII 185
            P E    + +  R     L  AGRR + T+ T    +A  +    + YP  GE   LA +
Sbjct: 1710 PIE----EEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASL 1765

Query: 186  TKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTKEVTAS 245
              +    V  WF NAR++ +K          +GG      GG   + GC           
Sbjct: 1766 LGLASRVVVVWFQNARQKARKN-------ACEGG-SMPTGGGTGGASGCRRCHATFSCVF 1817

Query: 246  QEARGL-RLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGP 295
            +  R L +  D + LEEEEEE E  E+EE V    +   E  +G +   GP
Sbjct: 1818 ELVRHLKKCYDDQTLEEEEEEAERGEEEEEVE---EEEVEEEQGLEPPAGP 1865


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 63/231 (27%), Positives = 91/231 (39%), Gaps = 27/231 (11%)

Query: 77   AAAAAQSYPGYLPYSPEPP--------SLYGALNPQYEFKEAAGSFTSS---LAQPGAYY 125
            AA   +SY    P   EPP        S    L P +   E     T +    ++ G ++
Sbjct: 1650 AAQFRKSYDSLYPPLAEPPKPPDGSLDSPVPHLGPPFLVPEPEAGGTRAPEERSRAGGHW 1709

Query: 126  PYERTLGQYQYERYGAVELSGAGRRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAII 185
            P E    + +  R     L  AGRR + T+ T    +A  +    + YP  GE   LA +
Sbjct: 1710 PIE----EEESSRGNLPPLVPAGRRFSRTKFTEFQTQALQSFFETSAYPKDGEVERLASL 1765

Query: 186  TKMTLTQVSTWFANARRRLKKENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTKEVTAS 245
              +    V  WF NAR++ +K          +GG      GG   + GC           
Sbjct: 1766 LGLASRVVVVWFQNARQKARKN-------ACEGG-SMPTGGGTGGASGCRRCHATFSCVF 1817

Query: 246  QEARGL-RLSDLEDLEEEEEEEEEAEDEEVVATAGDRLTEFRKGAQSLPGP 295
            +  R L +  D + LEEEEEE E  E+EE V    +   E  +G +   GP
Sbjct: 1818 ELVRHLKKCYDDQTLEEEEEEAERGEEEEEVE---EEEVEEEQGLEPPAGP 1865


>gi|34328941 TGFB-induced factor homeobox 2-like, X-linked [Homo
           sapiens]
          Length = 241

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 24/56 (42%), Positives = 36/56 (64%)

Query: 149 RRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 204
           R+ N   E+   L+ W+ +HR   YP++ EK ML+  T ++L Q+S WF NARRR+
Sbjct: 53  RKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLQISNWFINARRRI 108


>gi|57863279 Meis1, myeloid ecotropic viral integration site 1
           homolog 3 isoform 2 [Homo sapiens]
          Length = 358

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 26/61 (42%), Positives = 39/61 (63%), Gaps = 5/61 (8%)

Query: 149 RRKNATRE-----TTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRR 203
           RR+N  R       T+ ++AWL +H  +PYP++ +K  LA  T +T+ QV+ WF NARRR
Sbjct: 243 RRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRR 302

Query: 204 L 204
           +
Sbjct: 303 I 303


>gi|21245108 TGFB-induced factor homeobox 2-like, Y-linked [Homo
           sapiens]
          Length = 185

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 23/56 (41%), Positives = 36/56 (64%)

Query: 149 RRKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 204
           R+ N   E+   L+ W+ +HR   YP++ EK ML+  T ++L ++S WF NARRR+
Sbjct: 53  RKGNLPAESVKILRDWMYKHRFKAYPSEEEKQMLSEKTNLSLLRISNWFINARRRI 108


>gi|4505151 Meis homeobox 1 [Homo sapiens]
          Length = 390

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 22/47 (46%), Positives = 34/47 (72%)

Query: 158 TSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 204
           T+ ++AWL +H  +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct: 284 TNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI 330


>gi|27502383 Meis homeobox 2 isoform h [Homo sapiens]
          Length = 306

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 22/47 (46%), Positives = 34/47 (72%)

Query: 158 TSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 204
           T+ ++AWL +H  +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct: 200 TNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI 246


>gi|27502381 Meis homeobox 2 isoform g [Homo sapiens]
          Length = 388

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 22/47 (46%), Positives = 34/47 (72%)

Query: 158 TSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 204
           T+ ++AWL +H  +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct: 275 TNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI 321


>gi|24762244 Meis homeobox 2 isoform a [Homo sapiens]
          Length = 401

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 22/47 (46%), Positives = 34/47 (72%)

Query: 158 TSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRL 204
           T+ ++AWL +H  +PYP++ +K  LA  T +T+ QV+ WF NARRR+
Sbjct: 288 TNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI 334


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,417,781
Number of Sequences: 37866
Number of extensions: 1117611
Number of successful extensions: 14121
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 425
Number of HSP's successfully gapped in prelim test: 371
Number of HSP's that attempted gapping in prelim test: 8585
Number of HSP's gapped (non-prelim): 2830
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.