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Search of human proteins with 125988409
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|125988409 RED protein [Homo sapiens]
(557 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|125988409 RED protein [Homo sapiens] 1126 0.0
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 85 2e-16
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 81 3e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 77 4e-14
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 76 9e-14
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 76 9e-14
gi|14670268 RD RNA-binding protein [Homo sapiens] 75 2e-13
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 74 4e-13
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 72 2e-12
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 71 2e-12
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 71 3e-12
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 71 3e-12
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 70 4e-12
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 69 9e-12
gi|10190682 chromobox homolog 8 [Homo sapiens] 69 1e-11
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 67 3e-11
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 65 2e-10
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 64 5e-10
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 64 5e-10
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 64 5e-10
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 63 6e-10
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 63 6e-10
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 62 1e-09
gi|148746195 trichohyalin [Homo sapiens] 62 2e-09
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 62 2e-09
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 60 5e-09
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 60 5e-09
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 60 7e-09
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 60 7e-09
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 59 1e-08
>gi|125988409 RED protein [Homo sapiens]
Length = 557
Score = 1126 bits (2913), Expect = 0.0
Identities = 557/557 (100%), Positives = 557/557 (100%)
Query: 1 MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEM 60
MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEM
Sbjct: 1 MPERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEM 60
Query: 61 PREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELI 120
PREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELI
Sbjct: 61 PREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELI 120
Query: 121 STTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIAS 180
STTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIAS
Sbjct: 121 STTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIAS 180
Query: 181 KEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYV 240
KEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYV
Sbjct: 181 KEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYV 240
Query: 241 VDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKK 300
VDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKK
Sbjct: 241 VDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKK 300
Query: 301 KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERER 360
KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERER
Sbjct: 301 KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERER 360
Query: 361 ERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGW 420
ERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGW
Sbjct: 361 ERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGW 420
Query: 421 EGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGR 480
EGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGR
Sbjct: 421 EGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGR 480
Query: 481 WDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIE 540
WDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIE
Sbjct: 481 WDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIE 540
Query: 541 KRKKMEADGVEVKRPKY 557
KRKKMEADGVEVKRPKY
Sbjct: 541 KRKKMEADGVEVKRPKY 557
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 84.7 bits (208), Expect = 2e-16
Identities = 85/329 (25%), Positives = 142/329 (43%), Gaps = 60/329 (18%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYE 115
R + RE ++D R RK+ + + R +E ERER+ ++ RDR +E+ K+ E
Sbjct: 73 RETDRKRERRREKD---RHRKRDRHRERQRDREKERERQ-TDRERDRQREKERNRQKERE 128
Query: 116 -ETELISTTANYRAVGPTAEADKSA-AEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQK 173
ETE R E ++ AEK R+ + + ++
Sbjct: 129 RETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE--------------------RQ 168
Query: 174 VRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFK-TRLGRNVYRMLFKSKAYERNELF 232
+ E +++ E E + ++E ++ + ENK E + + GR R ER
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQ- 227
Query: 233 LPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQG 292
D D T R K +A+ + R+
Sbjct: 228 -----------TDRERDRQRKTEREREK------QAERERASE--------------RET 256
Query: 293 TRNKKLKK-KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERD 351
R+K+ ++ +D+ + +++ E + +T R +ER+R RERER+R R
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316
Query: 352 RDRDRERERERDRERERERDREREEEKKR 380
R+R+RERERER+R+RE ERDRE+E E+KR
Sbjct: 317 RERERERERERERQRETERDREKERERKR 345
Score = 74.3 bits (181), Expect = 3e-13
Identities = 86/393 (21%), Positives = 157/393 (39%), Gaps = 85/393 (21%)
Query: 62 REYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELIS 121
RE N ++ RR K+++ R++E RE++ K RDR +ER+ K+ E
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRK-RDRHRERQRDREKERERQ---- 108
Query: 122 TTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASK 181
R E +++ ++R + + G D + ++ R A K
Sbjct: 109 ---TDRERDRQREKERNRQKERERETEREGERGRDRQTD--------GQRERERQRDAEK 157
Query: 182 EKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVV 241
E+E + E+ Q++T+++ E + E + R R K E
Sbjct: 158 ERERQTDRER-QRQTERNRQKEREREKNRQERRERERQREKENKTE-------------- 202
Query: 242 DLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKK 301
D +++ R + QT R+ R +K +++
Sbjct: 203 ---DRHSERGRERERERETETETERKRQTD------------------RERDRQRKTERE 241
Query: 302 DKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRER----------- 350
+ + E ++ E + T RDKERER R+R+RDR+R
Sbjct: 242 REKQAERERASERE----------------TERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 351 ------DRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTK 404
+RDR+ ER+RER RERERER+R R+ E++R E+ + + D +K +
Sbjct: 286 KRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKR 345
Query: 405 ELIKSINEKFAGSAGWEGTESLKKPEDKKQLGD 437
+ ++ + G EG ++ ++++ D
Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERD 378
Score = 73.6 bits (179), Expect = 5e-13
Identities = 85/377 (22%), Positives = 153/377 (40%), Gaps = 41/377 (10%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELA-EKYRDRAKER---RDG 109
+ R E R+ + + D R+R+K+ K R++E ERE E ++ D +ER RD
Sbjct: 99 RDREKERERQTDRERD---RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDA 155
Query: 110 VNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFA 169
+ +T+ R E +K+ E+R + Q K E H +G +
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK--ENKTEDRHSERGRERE 213
Query: 170 LLQKVRAEIASKEK--EEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYE 227
++ E K + E + K ++E +K + E E +T + R + + +
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 228 RNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILS 287
R + R + D T R + E + K +
Sbjct: 274 RRQ---KERERQTDRKRQRRTERDRETERKRERQRERERERERN--------RKRERERE 322
Query: 288 YLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERE-- 345
R+ R ++ ++ + + E K+ + +M+ + + R++ERER R+R+
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSA 382
Query: 346 ---RDRERDRDRDRERERERD--------------RERERERDREREEEKKRHSYFEKPK 388
+RERDRDRDR++ERER RERE++R+ ER E+ R +K +
Sbjct: 383 REREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR 442
Query: 389 VDDEPMDVDKGPGSTKE 405
D D+ G ++
Sbjct: 443 ERDRERQTDRQAGRQRK 459
Score = 71.6 bits (174), Expect = 2e-12
Identities = 36/107 (33%), Positives = 64/107 (59%)
Query: 292 GTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERD 351
G ++ ++K++ + EK+ E + + + K R +ER+R RE+ER+R+ D
Sbjct: 51 GDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD 110
Query: 352 RDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDK 398
R+RDR+RE+ER+R++ERER+ ERE E+ R + + + D +K
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEK 157
Score = 57.4 bits (137), Expect = 3e-08
Identities = 47/198 (23%), Positives = 84/198 (42%), Gaps = 28/198 (14%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
R KERER RE+ R ER+ DR RER RE+DR R+R+R RER+ ++++ E+ + D
Sbjct: 58 RQKERERRREK-RQTERETDRKRERRREKDRHRKRDRHRERQRDREK----ERERQTDRE 112
Query: 394 MDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPATM 453
D + ++ + + G G + ++ ++++
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR------------------- 153
Query: 454 DDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEG 513
D + + + D + Q + R ++E E +E K ++ G
Sbjct: 154 -DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHS---ERG 209
Query: 514 RKTRRFKETNDKAELDRQ 531
R+ R +ET + E RQ
Sbjct: 210 RERERERETETETERKRQ 227
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 80.9 bits (198), Expect = 3e-15
Identities = 48/105 (45%), Positives = 66/105 (62%), Gaps = 7/105 (6%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
R+K+R R RE+ RDRER+R+R+RERERER+RERERER+RERE E++R EK K D
Sbjct: 377 RNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER--EKDKKRDRE 434
Query: 394 MDVDKGPGSTKELIKSINEKFAG----SAGWEGTESLKKPEDKKQ 434
D ++ ++L + + EK A WE E K E +K+
Sbjct: 435 ED-EEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKE 478
Score = 80.1 bits (196), Expect = 5e-15
Identities = 74/316 (23%), Positives = 143/316 (45%), Gaps = 40/316 (12%)
Query: 252 IPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLE-EKK 310
IP LI +K D +E + D++ ++++ ++ K K+K++ ++E E++
Sbjct: 254 IPYPLI-TKEDINAIEMEED--KRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERR 310
Query: 311 PPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERER 370
E + E + + R++ERE+ +ERER+RERDRDRDR +ER+RDR+RER+R
Sbjct: 311 ERERER---ERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDR 367
Query: 371 DREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPE 430
DR+RE R+ + + + ++ +E + + E ++ +
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK 427
Query: 431 DKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGP------LGRWDFD 484
DKK+ D D ++ + K+++ ++ L W+
Sbjct: 428 DKKR--------------------DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIR 467
Query: 485 TQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISA----IIE 540
+++ EY E + + E ++ + F E D D ++ + SA + +
Sbjct: 468 ERKKTREYEKEAEREEERRREMA---KEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRD 524
Query: 541 KRKKMEADGVEVKRPK 556
+ K+MEAD + KR K
Sbjct: 525 REKEMEADERDRKREK 540
Score = 55.5 bits (132), Expect = 1e-07
Identities = 85/417 (20%), Positives = 165/417 (39%), Gaps = 72/417 (17%)
Query: 55 SRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDY 114
S+ + ++ E++ + R++ + R++E ERERE E+ R+R +ER K+
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 115 EETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKV 174
E + D+ ++R + + D E + + K
Sbjct: 342 ERER-------------ERDRDRDRTKERDRDRDRERDRDRDRERS--------SDRNKD 380
Query: 175 RAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLP 234
R+ K ++ E E+ ++E +++ + E + E + R R K K +R E
Sbjct: 381 RSRSREKSRDRERERER-EREREREREREREREREREREREREREREKDKKRDREE---- 435
Query: 235 GRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTR 294
D +D Y + L +A Q L +I K T+ Y ++ R
Sbjct: 436 -------DEEDAYERRKLERKLREKEA-----AYQERLKNWEIRERKKTR--EYEKEAER 481
Query: 295 NKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRER-ERDRERDRD 353
++ +++ + + K D + D Y + R ++RE+ E ERDR+R+++
Sbjct: 482 EEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE 541
Query: 354 R-----------------------DRERERERDRERERERDREREEEKKRHSYFEKPKVD 390
++E ER R + ++E + E EEE+K+ EK +
Sbjct: 542 ELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQ----EKEEKR 597
Query: 391 DEPMDVDKGPGS---TKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNS 444
+EPM+ ++ P K ++ I+ + S+ G + P D+ G NS
Sbjct: 598 EEPMEEEEEPEQKPCLKPTLRPISSAPSVSSA-SGNATPNTPGDESPCGIIIPHENS 653
Score = 40.0 bits (92), Expect = 0.006
Identities = 41/185 (22%), Positives = 80/185 (43%), Gaps = 32/185 (17%)
Query: 54 KSRHHEMPREYNEDEDPA-------------------------ARRRKKKSYYAKLRQQE 88
+ R + R+ EDE+ A R RKK Y K ++E
Sbjct: 423 REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAERE 482
Query: 89 IERERELAEKYRDRAKERRDGVNKDYEETELISTTA---NYRAVGPTAEADKSAAEKRRQ 145
ER RE+A++ + R KE + + D ++ + +A R EAD+ ++ ++
Sbjct: 483 EERRREMAKEAK-RLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE 541
Query: 146 LIQESK---FLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDP 202
++E + G + ++ ++ ++ + +I + + EEE EK +KE K++E
Sbjct: 542 ELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPM 601
Query: 203 ENKIE 207
E + E
Sbjct: 602 EEEEE 606
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 77.0 bits (188), Expect = 4e-14
Identities = 70/231 (30%), Positives = 109/231 (47%), Gaps = 36/231 (15%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDR-----------ERERERDREREEEKKRHS 382
R++ERER +ER+R+R+RDRD DRERERER+R ERERER+RERE E++R
Sbjct: 713 REREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERER 772
Query: 383 YFEKPKVDDEPM-------DVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQL 435
E+ + D+ D DKG +E + I E G + +S K+ ++
Sbjct: 773 ERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNE--- 829
Query: 436 GDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNN 495
+ P + + DSD Y+ D N+K L QE S ++
Sbjct: 830 ------GSPSPRQSPKRRREHSPDSDA---YNSGDDKNEKHRLLSQVVRPQESRSLSPSH 880
Query: 496 KEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKME 546
+ G E RK R KE++ + E +K+S++ ++R++ E
Sbjct: 881 -----LTEDRQGRWKEEDRKPER-KESSRRYEEQELKEKVSSVDKQREQTE 925
Score = 74.7 bits (182), Expect = 2e-13
Identities = 36/80 (45%), Positives = 55/80 (68%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
R+++RER R+RER+RER+R+RDRERE+ER+ ERER R+RERE EK+R ++ + D
Sbjct: 677 RERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRE 736
Query: 394 MDVDKGPGSTKELIKSINEK 413
+ ++ KE + E+
Sbjct: 737 RERERERDREKEREREREER 756
Score = 72.8 bits (177), Expect = 8e-13
Identities = 35/63 (55%), Positives = 46/63 (73%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPM 394
D+ ER RER+R+RERDR+R+RERERERDRERE+ER+ ERE ++R EK + +
Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729
Query: 395 DVD 397
D D
Sbjct: 730 DRD 732
Score = 71.6 bits (174), Expect = 2e-12
Identities = 36/75 (48%), Positives = 48/75 (64%)
Query: 331 KTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVD 390
+ R +R R RERDRER+RDR+RERERER+R+RERE++RE E E+ R E+ K
Sbjct: 664 RVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER 723
Query: 391 DEPMDVDKGPGSTKE 405
D D D+ +E
Sbjct: 724 DRERDRDRDHDRERE 738
Score = 71.2 bits (173), Expect = 2e-12
Identities = 55/171 (32%), Positives = 86/171 (50%), Gaps = 21/171 (12%)
Query: 333 PRDKERERYRERERDRERDRDRDRERERER------DRERERERDREREEEKKRHSYFEK 386
PR+++R+R RERER+RERD+ RD +RERER +R+R+R+RDR E + +
Sbjct: 1332 PRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCE 1391
Query: 387 PKVDDE-PMDVDKGPGSTKELIKSINEKFAGSAGW-------EGTESLKKPEDKKQLGDF 438
K++ E D++ + L K +K GS E TESL+ +D+ +L D
Sbjct: 1392 AKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDA 1451
Query: 439 FGMSNSYAECYPATMDD-----MAVDSDEEVDYSKMDQGNKKGPLGRWDFD 484
+ + E Y DD +A D+++ D + D+ PL D D
Sbjct: 1452 HSLGSGAGEGYEPISDDELDEILAGDAEKRED--QQDEEKMPDPLDVIDVD 1500
Score = 69.3 bits (168), Expect = 9e-12
Identities = 31/59 (52%), Positives = 47/59 (79%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDE 392
+++E ER R RER+RER+++RDRER+R+RD +RERER+RER+ EK+R E+ + + E
Sbjct: 703 KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERE 761
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/112 (36%), Positives = 66/112 (58%), Gaps = 19/112 (16%)
Query: 287 SYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERER 346
S +R RN +L++ ++ EE++ D + R +ER+R RER+R
Sbjct: 643 SPIRHQGRNDELERDERR--EERRVDRVD-------------DRRDERARERDRERERDR 687
Query: 347 DRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDK 398
+RER+R+R+R+RERE++RE ERER RERE E+++ E+ + D D D+
Sbjct: 688 ERERERERERDREREKERELERERAREREREREK----ERDRERDRDRDHDR 735
Score = 68.6 bits (166), Expect = 1e-11
Identities = 30/59 (50%), Positives = 46/59 (77%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDE 392
R++E+ER ERER RER+R+R++ER+RERDR+R+ +R+RERE E+ R E+ + + E
Sbjct: 699 REREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERE 757
Score = 67.8 bits (164), Expect = 3e-11
Identities = 51/192 (26%), Positives = 83/192 (43%), Gaps = 17/192 (8%)
Query: 299 KKKDKGKLEEKKPPEADMNIFEDIG-----DYVPSTTKTPRDKERERYRERERDRERDRD 353
++ + + PE+D + G D + + D+ERER R R RE DRD
Sbjct: 1267 RQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRD 1326
Query: 354 RDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKG-------PGSTKEL 406
D++ R RDR+R RER+RERE +K+R E+ ++ + ++ D+ S E
Sbjct: 1327 ADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIES 1386
Query: 407 IKSINEKFAG--SAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEV 464
+K K G E T DK+++ G + E + + D+E
Sbjct: 1387 VKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDE- 1445
Query: 465 DYSKMDQGNKKG 476
SK+D + G
Sbjct: 1446 --SKLDDAHSLG 1455
Score = 67.4 bits (163), Expect = 3e-11
Identities = 29/59 (49%), Positives = 47/59 (79%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDE 392
R+KERE RER R+RER+R+++R+RER+RDR+ +RER+RERE ++++ E+ + + E
Sbjct: 701 REKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERE 759
Score = 47.4 bits (111), Expect = 4e-05
Identities = 50/247 (20%), Positives = 103/247 (41%), Gaps = 22/247 (8%)
Query: 180 SKEKEEEELMEKPQKETKKDEDPENKI------EFKTRLGRNVYRMLF----KSKAYERN 229
S++ + M ++TK+ DP + +++ R GR+ +R +S++Y RN
Sbjct: 473 SRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRN 532
Query: 230 ELFLPGRMAYVVDLDDEYADTDIPTTLI-RSKADCPTMEAQTTLTTNDIVISKLTQILSY 288
L + + + ++I + RS+ P + + + + I + +Y
Sbjct: 533 HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592
Query: 289 LRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIG----------DYVPSTTKTPRDKER 338
++D+ + + D + G D PS+ + +
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 652
Query: 339 ERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDK 398
E R+ ER ER DR +R ER RER+RER+R+RE E++R ++ + + ++ ++
Sbjct: 653 ELERD-ERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERER 711
Query: 399 GPGSTKE 405
+E
Sbjct: 712 ARERERE 718
Score = 43.1 bits (100), Expect = 7e-04
Identities = 112/540 (20%), Positives = 200/540 (37%), Gaps = 112/540 (20%)
Query: 3 ERDSEPFSNPLAPDGH--DVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEM 60
ERD P S+P+ G +++ + ++ D R+ RA + R E
Sbjct: 636 ERDQRP-SSPIRHQGRNDELERDERREERRVDRVDDRR---DERARERDRERERDRERER 691
Query: 61 PREYNEDEDPAARRRKKKSYYAKLRQQEIEREREL---AEKYRDRAKERRDGVNKDYEET 117
RE D + R ++++ + R++E ERE+E ++ RD +ER +D E+
Sbjct: 692 ERERERDRE---REKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKE 748
Query: 118 ELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAE 177
E ++ E+ R+ +E + ++ R
Sbjct: 749 R---------------EREREERERERERERERE-----------------RERERERER 776
Query: 178 IASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNE-----LF 232
++KE E + K+ +D+ E + E + KSK RNE
Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQ 836
Query: 233 LPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQG 292
P R D Y D R + + +L+ S LT+ RQG
Sbjct: 837 SPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSP-----SHLTED----RQG 887
Query: 293 TRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDR 352
R K+ +K + K ++ E +++ + V S DK+RE+ E R R +
Sbjct: 888 -RWKEEDRKPERKESSRRYEE------QELKEKVSSV-----DKQREQTEILESSRMRAQ 935
Query: 353 DRDRERERERDRERERERDREREEEKKRHSYFEKP--KVDDEPMDVDKGPGSTKELIKSI 410
D + E DRE DR +E KK+ +KP K ++ + +++G E
Sbjct: 936 DIIGHHQSE-DRETS---DRAHDENKKKAKIQKKPIKKKKEDDVGIERG---NIETTSED 988
Query: 411 NEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDEEVDYSKMD 470
+ F+ G + KK +KK+ + D + +E SK
Sbjct: 989 GQVFSPKKGQK-----KKSIEKKR---------------KKSKGDSDISDEEAAQQSKKK 1028
Query: 471 QGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDR 530
+G + P+ T+EE E N K + ++ S+ ++ F + +D+ DR
Sbjct: 1029 RGPRTPPI-----TTKEELVEMCNGKNGI--------LEDSQKKEDTAFSDWSDEDVPDR 1075
Score = 37.4 bits (85), Expect = 0.036
Identities = 47/210 (22%), Positives = 89/210 (42%), Gaps = 21/210 (10%)
Query: 180 SKEKEEEELMEKPQKETKKDEDPENKI--EFKTRLGRNVYRMLFKSKAYERNELFLPGRM 237
+KE+ E E + ET +D+ I ++ L + R + + + + + R
Sbjct: 130 TKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKRE 189
Query: 238 AYVV--DLDDEYADTDI-PTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTR 294
++ ++ E + + P+ +R + P ++ ++ K + + S L R
Sbjct: 190 EIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQR 249
Query: 295 NKKLKK-KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE-RDR 352
N K + K KG PP I EDI + K ++K + + R E+ R+ +DR
Sbjct: 250 NSKTNQSKKKGPRTPSPPPP----IPEDI-----ALGKKYKEKYKVKDRIEEKTRDGKDR 300
Query: 353 DRDRERERERDRERERERDREREEEKKRHS 382
RD ER+RE+ R++ R + HS
Sbjct: 301 GRDFERQREK-----RDKPRSTSPAGQHHS 325
Score = 37.0 bits (84), Expect = 0.048
Identities = 19/74 (25%), Positives = 33/74 (44%)
Query: 307 EEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRER 366
+ K+ P + + G + T D+ ER + R+R++D ERE E+D+
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 367 ERERDREREEEKKR 380
R+ +RE R
Sbjct: 443 SRDHRDDREPRDGR 456
Score = 35.8 bits (81), Expect = 0.11
Identities = 29/102 (28%), Positives = 44/102 (43%), Gaps = 13/102 (12%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
R+ TR K+ ++KD E++ E D + D D + PRD R RDR
Sbjct: 417 REDTRGKRDREKDS---REEREYEQDQSSSRDHRD-----DREPRDGRDRRDARDTRDRR 468
Query: 350 RDRD----RDRERERERDRERERERD-REREEEKKRHSYFEK 386
RD RD R+ R+ + RD R+ + H Y ++
Sbjct: 469 ELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDR 510
Score = 35.0 bits (79), Expect = 0.18
Identities = 26/118 (22%), Positives = 50/118 (42%), Gaps = 17/118 (14%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
+Q + ++KG+ + ++ ++ E D T+ RD+E++ ERE +++
Sbjct: 385 KQSPPRHRSPMREKGRHDHERTSQSHDRRHERRED-----TRGKRDREKDSREEREYEQD 439
Query: 350 RDRDRDRERERE----RDR--------ERERERDREREEEKKRHSYFEKPKVDDEPMD 395
+ RD +RE RDR RE R+ + ++ Y K +P D
Sbjct: 440 QSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRD 497
Score = 29.6 bits (65), Expect = 7.6
Identities = 18/78 (23%), Positives = 33/78 (42%), Gaps = 4/78 (5%)
Query: 327 PSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERD----REREEEKKRHS 382
PS + + +++ R R RE+ R + DR ER D R+RE++ +
Sbjct: 375 PSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREER 434
Query: 383 YFEKPKVDDEPMDVDKGP 400
+E+ + D+ P
Sbjct: 435 EYEQDQSSSRDHRDDREP 452
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 75.9 bits (185), Expect = 9e-14
Identities = 36/80 (45%), Positives = 58/80 (72%), Gaps = 4/80 (5%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
R+KERER +ERE+++ER +++DR++ERE+DRE+++E+DRERE EK+ EK + ++
Sbjct: 395 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH----EKDRDKEKE 450
Query: 394 MDVDKGPGSTKELIKSINEK 413
+ DK K+ K I+EK
Sbjct: 451 KEQDKEKEREKDRSKEIDEK 470
Score = 68.9 bits (167), Expect = 1e-11
Identities = 36/114 (31%), Positives = 67/114 (58%), Gaps = 20/114 (17%)
Query: 290 RQGTRNK-----KLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRER 344
R+ TR K ++K+KD+ K E++ + R K ++R +ER
Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREK---------------EKERGKNKDRDKER 421
Query: 345 ERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDK 398
E+DRE+D+++DRERERE++ E++R++++E+E++K++ ++ K DE DK
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 475
Score = 47.4 bits (111), Expect = 4e-05
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 35/113 (30%)
Query: 328 STTKTPRDKERERYRERERDRERDRDR--------------------------------- 354
S K + K R R R R R++DR R
Sbjct: 324 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 383
Query: 355 --DRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKE 405
++ER +E+DRE+ERER++ERE+EK+R ++ K ++ + DK +E
Sbjct: 384 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/105 (26%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Query: 330 TKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKV 389
+K+P K+R + RER + R R RD+ ++ R++ +E+ER +E++ EK+R E+ K
Sbjct: 351 SKSPH-KKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREKEREREKEREKE 408
Query: 390 DDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQ 434
+ + D+ K+ K + E + K ++K+Q
Sbjct: 409 KERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 453
Score = 43.9 bits (102), Expect = 4e-04
Identities = 74/358 (20%), Positives = 133/358 (37%), Gaps = 88/358 (24%)
Query: 25 SFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKL 84
S H+S+ N + R+ SKSR R + D R+K ++
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 390
Query: 85 RQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRR 144
++++ E+ERE EK R++ KER G NKD ++ E DK +R
Sbjct: 391 KEKDREKERE-REKEREKEKER--GKNKDRDKER-----------EKDREKDKEKDRERE 436
Query: 145 QLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKP-QKETKKDEDPE 203
+ +K + KEKE+E+ EK +K+ K+ D +
Sbjct: 437 R--------------------------EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 204 NKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADC 263
K + K+R Y +S++ R R + RS
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS------------------SRSPRTS 512
Query: 264 PTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGK--LEEKKPPEADMNIFED 321
T++ +++ + + +RNKK KK++K + + E++ E ++ +
Sbjct: 513 KTIKRKSSRSPS---------------PRSRNKKDKKREKERDHISERRERERSTSMRKS 557
Query: 322 IGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
D K +K +E+E ++E D +E + ++D R EE K
Sbjct: 558 SND---RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD---------DKDAPRTEENK 603
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 15/96 (15%)
Query: 299 KKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRER 358
K KD+ K E +K E D +D + RDKE+E+ +++E++RE+DR ++ +
Sbjct: 413 KNKDRDK-EREKDREKDKE--KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 469
Query: 359 ERERDRE------------RERERDREREEEKKRHS 382
+R++D++ R R RER + R S
Sbjct: 470 KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 505
Score = 36.6 bits (83), Expect = 0.062
Identities = 67/365 (18%), Positives = 132/365 (36%), Gaps = 56/365 (15%)
Query: 41 MTPRAAPTSAPPSKSRHHEM---------PREYNEDEDPAARRRKKKSYYAKLRQQEIER 91
MTP+AA R E P +E R R ++ + R
Sbjct: 266 MTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 325
Query: 92 ERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESK 151
+ K+R R+ R KD R+ P + KS ++ + S+
Sbjct: 326 RKRSQSKHRSRSHNRSRSRQKDRR-----------RSKSPHKKRSKSRERRKSRSRSHSR 374
Query: 152 FLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTR 211
D K ++V+ + KE+E E+ EK +KE K++D + + E
Sbjct: 375 DKRKDTREKIKEK-------ERVKEKDREKEREREKEREK-EKERGKNKDRDKEREKDRE 426
Query: 212 LGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTT 271
+ R + K +E++ D+ + + R K ++ +
Sbjct: 427 KDKEKDREREREKEHEKDR--------------DKEKEKEQDKEKEREKDRSKEIDEKRK 472
Query: 272 LTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTK 331
+ R +R ++ ++ + P I +++
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS----RSPRTSKTIKR-------KSSR 521
Query: 332 TPRDKERERYRERERDRERDRDRDRERERERDRE-RERERDREREEEKKRHSYFEKPKVD 390
+P + R + ++++R++ERD +R RERER R+ DR+ +E+ +++S K K
Sbjct: 522 SPSPRSRNK-KDKKREKERDHISER-RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 579
Query: 391 DEPMD 395
++ D
Sbjct: 580 NKEPD 584
Score = 36.2 bits (82), Expect = 0.081
Identities = 25/107 (23%), Positives = 48/107 (44%), Gaps = 8/107 (7%)
Query: 330 TKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKV 389
+K+ + R+R + + R R +R R R++DR R + ++R + ++R +
Sbjct: 314 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 373
Query: 390 DDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLG 436
D+ D T+E IK E+ + E K+ E +K+ G
Sbjct: 374 RDKRKD-------TREKIKE-KERVKEKDREKEREREKEREKEKERG 412
Score = 35.8 bits (81), Expect = 0.11
Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 19/129 (14%)
Query: 296 KKLKKKDKGKLEEK-KPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDR 354
+K K++DK K EK + E D +D P + + R RER R R R R
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 507
Query: 355 D------------------RERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDV 396
++++ RE+ER+ ER E ++ S + D +
Sbjct: 508 SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKL 567
Query: 397 DKGPGSTKE 405
+K S KE
Sbjct: 568 EKNSTSLKE 576
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 75.9 bits (185), Expect = 9e-14
Identities = 36/80 (45%), Positives = 58/80 (72%), Gaps = 4/80 (5%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
R+KERER +ERE+++ER +++DR++ERE+DRE+++E+DRERE EK+ EK + ++
Sbjct: 279 REKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEH----EKDRDKEKE 334
Query: 394 MDVDKGPGSTKELIKSINEK 413
+ DK K+ K I+EK
Sbjct: 335 KEQDKEKEREKDRSKEIDEK 354
Score = 68.9 bits (167), Expect = 1e-11
Identities = 36/114 (31%), Positives = 67/114 (58%), Gaps = 20/114 (17%)
Query: 290 RQGTRNK-----KLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRER 344
R+ TR K ++K+KD+ K E++ + R K ++R +ER
Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREK---------------EKERGKNKDRDKER 305
Query: 345 ERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDK 398
E+DRE+D+++DRERERE++ E++R++++E+E++K++ ++ K DE DK
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDK 359
Score = 47.4 bits (111), Expect = 4e-05
Identities = 31/113 (27%), Positives = 49/113 (43%), Gaps = 35/113 (30%)
Query: 328 STTKTPRDKERERYRERERDRERDRDR--------------------------------- 354
S K + K R R R R R++DR R
Sbjct: 208 SRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK 267
Query: 355 --DRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKE 405
++ER +E+DRE+ERER++ERE+EK+R ++ K ++ + DK +E
Sbjct: 268 IKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/105 (26%), Positives = 54/105 (51%), Gaps = 2/105 (1%)
Query: 330 TKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKV 389
+K+P K+R + RER + R R RD+ ++ R++ +E+ER +E++ EK+R E+ K
Sbjct: 235 SKSPH-KKRSKSRERRKSRSRSHSRDKRKDT-REKIKEKERVKEKDREKEREREKEREKE 292
Query: 390 DDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQ 434
+ + D+ K+ K + E + K ++K+Q
Sbjct: 293 KERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQ 337
Score = 43.9 bits (102), Expect = 4e-04
Identities = 74/358 (20%), Positives = 133/358 (37%), Gaps = 88/358 (24%)
Query: 25 SFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKL 84
S H+S+ N + R+ SKSR R + D R+K ++
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 274
Query: 85 RQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRR 144
++++ E+ERE EK R++ KER G NKD ++ E DK +R
Sbjct: 275 KEKDREKERE-REKEREKEKER--GKNKDRDKER-----------EKDREKDKEKDRERE 320
Query: 145 QLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKP-QKETKKDEDPE 203
+ +K + KEKE+E+ EK +K+ K+ D +
Sbjct: 321 R--------------------------EKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 204 NKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADC 263
K + K+R Y +S++ R R + RS
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS------------------SRSPRTS 396
Query: 264 PTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGK--LEEKKPPEADMNIFED 321
T++ +++ + + +RNKK KK++K + + E++ E ++ +
Sbjct: 397 KTIKRKSSRSPS---------------PRSRNKKDKKREKERDHISERRERERSTSMRKS 441
Query: 322 IGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
D K +K +E+E ++E D +E + ++D R EE K
Sbjct: 442 SND---RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVD---------DKDAPRTEENK 487
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 15/96 (15%)
Query: 299 KKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRER 358
K KD+ K E +K E D +D + RDKE+E+ +++E++RE+DR ++ +
Sbjct: 297 KNKDRDK-EREKDREKDKE--KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE 353
Query: 359 ERERDRE------------RERERDREREEEKKRHS 382
+R++D++ R R RER + R S
Sbjct: 354 KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSS 389
Score = 36.6 bits (83), Expect = 0.062
Identities = 67/365 (18%), Positives = 132/365 (36%), Gaps = 56/365 (15%)
Query: 41 MTPRAAPTSAPPSKSRHHEM---------PREYNEDEDPAARRRKKKSYYAKLRQQEIER 91
MTP+AA R E P +E R R ++ + R
Sbjct: 150 MTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSR 209
Query: 92 ERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESK 151
+ K+R R+ R KD R+ P + KS ++ + S+
Sbjct: 210 RKRSQSKHRSRSHNRSRSRQKDRR-----------RSKSPHKKRSKSRERRKSRSRSHSR 258
Query: 152 FLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTR 211
D K ++V+ + KE+E E+ EK +KE K++D + + E
Sbjct: 259 DKRKDTREKIKEK-------ERVKEKDREKEREREKEREK-EKERGKNKDRDKEREKDRE 310
Query: 212 LGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTT 271
+ R + K +E++ D+ + + R K ++ +
Sbjct: 311 KDKEKDREREREKEHEKDR--------------DKEKEKEQDKEKEREKDRSKEIDEKRK 356
Query: 272 LTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTK 331
+ R +R ++ ++ + P I +++
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS----RSPRTSKTIKR-------KSSR 405
Query: 332 TPRDKERERYRERERDRERDRDRDRERERERDRE-RERERDREREEEKKRHSYFEKPKVD 390
+P + R + ++++R++ERD +R RERER R+ DR+ +E+ +++S K K
Sbjct: 406 SPSPRSRNK-KDKKREKERDHISER-RERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 463
Query: 391 DEPMD 395
++ D
Sbjct: 464 NKEPD 468
Score = 36.2 bits (82), Expect = 0.081
Identities = 25/107 (23%), Positives = 48/107 (44%), Gaps = 8/107 (7%)
Query: 330 TKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKV 389
+K+ + R+R + + R R +R R R++DR R + ++R + ++R +
Sbjct: 198 SKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHS 257
Query: 390 DDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLG 436
D+ D T+E IK E+ + E K+ E +K+ G
Sbjct: 258 RDKRKD-------TREKIKE-KERVKEKDREKEREREKEREKEKERG 296
Score = 35.8 bits (81), Expect = 0.11
Identities = 32/129 (24%), Positives = 50/129 (38%), Gaps = 19/129 (14%)
Query: 296 KKLKKKDKGKLEEK-KPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDR 354
+K K++DK K EK + E D +D P + + R RER R R R R
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR 391
Query: 355 D------------------RERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDV 396
++++ RE+ER+ ER E ++ S + D +
Sbjct: 392 SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKL 451
Query: 397 DKGPGSTKE 405
+K S KE
Sbjct: 452 EKNSTSLKE 460
>gi|14670268 RD RNA-binding protein [Homo sapiens]
Length = 380
Score = 75.1 bits (183), Expect = 2e-13
Identities = 30/53 (56%), Positives = 46/53 (86%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEK 386
RD++R+R R+R+RDR+RDR+RDR+R+R+RDR+RER+RDRER+ ++ R F +
Sbjct: 196 RDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRR 248
Score = 74.3 bits (181), Expect = 3e-13
Identities = 31/47 (65%), Positives = 42/47 (89%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKR 380
RD+ ER R+R+RDRERDRDRDR+R+RERDR+R+R+RDR+RE ++ R
Sbjct: 188 RDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDR 234
Score = 72.8 bits (177), Expect = 8e-13
Identities = 31/64 (48%), Positives = 48/64 (75%)
Query: 328 STTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
S+ PR + R+R ER RDR+RDR+RDR+R+R+RDRER+R+RDR+R+ +++R E+
Sbjct: 178 SSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERD 237
Query: 388 KVDD 391
+ D
Sbjct: 238 RDRD 241
Score = 72.0 bits (175), Expect = 1e-12
Identities = 30/54 (55%), Positives = 44/54 (81%)
Query: 327 PSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKR 380
P + R ER R R+R+R+R+RDRDRDR+RER+RDR+R+R+RDRER+ +++R
Sbjct: 183 PRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRER 236
Score = 71.2 bits (173), Expect = 2e-12
Identities = 34/53 (64%), Positives = 44/53 (83%), Gaps = 2/53 (3%)
Query: 334 RDKERERYRERERDRERD--RDRDRERERERDRERERERDREREEEKKRHSYF 384
RD+ER+R R+R+RDRERD RDRDR+R+RERDR+RER+RDR+RE +R F
Sbjct: 200 RDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSF 252
Score = 70.5 bits (171), Expect = 4e-12
Identities = 30/53 (56%), Positives = 44/53 (83%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
++ R+R R+RERDR+RDRDRDRER+R+RDR+R+R+R+R+R+ E+ R E P
Sbjct: 193 ERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDREGP 245
Score = 67.0 bits (162), Expect = 4e-11
Identities = 29/70 (41%), Positives = 47/70 (67%)
Query: 311 PPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERER 370
P D E G + ++ R ++R R R+RDR+R+RDRDR+R+R+R+R+R+R+R
Sbjct: 163 PRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDR 222
Query: 371 DREREEEKKR 380
DR+R+ E+ R
Sbjct: 223 DRDRDRERDR 232
Score = 64.7 bits (156), Expect = 2e-10
Identities = 28/58 (48%), Positives = 41/58 (70%)
Query: 338 RERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMD 395
R R R+R +R RDRDRDRER+R+RDR+R+RERDR+R+ ++ R ++ + D D
Sbjct: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRD 241
Score = 60.5 bits (145), Expect = 4e-09
Identities = 28/62 (45%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Query: 340 RYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDK- 398
R R R+R ER+RDRDR+RER+RDR+R+R+R+R+R+ ++ R E+ + + D D+
Sbjct: 184 RSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDRDRDRDRDRDRERDRDRERDRDRDRE 243
Query: 399 GP 400
GP
Sbjct: 244 GP 245
Score = 51.2 bits (121), Expect = 2e-06
Identities = 25/76 (32%), Positives = 41/76 (53%)
Query: 323 GDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382
GD P + ++ + R R RDR ER R+RDR+RER+RDR+R+ +++R
Sbjct: 159 GDGPPRSFDWGYEERSGAHSSASPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRERDR 218
Query: 383 YFEKPKVDDEPMDVDK 398
++ + D D D+
Sbjct: 219 DRDRDRDRDRERDRDR 234
Score = 45.8 bits (107), Expect = 1e-04
Identities = 21/50 (42%), Positives = 31/50 (62%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSY 383
RD++R+R R+R+R+R+RDR+RDR+R+RE R R K Y
Sbjct: 216 RDRDRDRDRDRDRERDRDRERDRDRDREGPFRRSDSFPERRAPRKGNTLY 265
Score = 31.6 bits (70), Expect = 2.0
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 46 APTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKE 105
A +SA P +SR + E N D D R + + R ++ ER+R+ ++ RDR +E
Sbjct: 176 AHSSASPPRSRSRDRSHERNRDRDRDRERDRDRD-----RDRDRERDRD-RDRDRDRDRE 229
Query: 106 R 106
R
Sbjct: 230 R 230
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 73.9 bits (180), Expect = 4e-13
Identities = 40/112 (35%), Positives = 63/112 (56%)
Query: 294 RNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRD 353
+ +K + +D+ + E++ E + N D R+K++ R RER+R RER+RD
Sbjct: 87 KTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERD 146
Query: 354 RDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKE 405
RDRE+ERER E++R+ RE E E++R EK K + D D+ + KE
Sbjct: 147 RDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKE 198
Score = 71.6 bits (174), Expect = 2e-12
Identities = 47/161 (29%), Positives = 80/161 (49%), Gaps = 7/161 (4%)
Query: 281 KLTQILSYLRQGTRNKKLKKKDKGKLEEK---KPPEADMNIFEDIGDYVPSTTKTPRDKE 337
K T+I + + + +++D+G+ E+ + E + +D + T+ RD+E
Sbjct: 117 KQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRE 176
Query: 338 RERYRERERDRERDRDRDRERERERDRERERERDR----EREEEKKRHSYFEKPKVDDEP 393
RE+ +ERE +R+RDR RD E+ERER +RER+R R ER+ E R E + +
Sbjct: 177 REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQ 236
Query: 394 MDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQ 434
D D+G +E + K + KK E+K++
Sbjct: 237 RDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRR 277
Score = 68.6 bits (166), Expect = 1e-11
Identities = 37/111 (33%), Positives = 64/111 (57%), Gaps = 8/111 (7%)
Query: 289 LRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDR 348
+R+ T ++ + + + + +K E + N + + + + K RER R+R R+R
Sbjct: 84 VREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRER 143
Query: 349 ERDRDRDRERER--------ERDRERERERDREREEEKKRHSYFEKPKVDD 391
ERDRDR++ERER +R+ E ERERDRERE++K+R + ++ + D
Sbjct: 144 ERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Score = 62.8 bits (151), Expect = 8e-10
Identities = 29/60 (48%), Positives = 43/60 (71%)
Query: 331 KTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVD 390
+T R+ ERE R RER R+RDR ++R+RER+R ER++ER +ER++E+K EK + D
Sbjct: 220 ETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
Score = 61.2 bits (147), Expect = 2e-09
Identities = 33/75 (44%), Positives = 45/75 (60%), Gaps = 19/75 (25%)
Query: 324 DYVPSTTKTPRDKERERYRER-------------------ERDRERDRDRDRERERERDR 364
D V T+ RD++R+R RER ERDRER++ + RERER+R R
Sbjct: 82 DRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGR 141
Query: 365 ERERERDREREEEKK 379
ERER+RDRE+E E++
Sbjct: 142 ERERDRDREKERERQ 156
Score = 60.1 bits (144), Expect = 5e-09
Identities = 26/55 (47%), Positives = 41/55 (74%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
R+ +R R R+R+RDR ++RDR+R+R+ ER +ER++ER +ER+E+KK E K
Sbjct: 227 RETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKK 281
Score = 55.1 bits (131), Expect = 2e-07
Identities = 68/299 (22%), Positives = 117/299 (39%), Gaps = 96/299 (32%)
Query: 85 RQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRR 144
RQ+E +R RE EK RDR ++R D E T R E ++ +++
Sbjct: 77 RQRERDRVREKTEKERDRDRKR------DRERRRKEKETNRNRDREKQTEIERDREREKQ 130
Query: 145 QLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPEN 204
+ + + G + E +EKE E ++T+KD D +
Sbjct: 131 KGRERERDRGRERERDR------------------DREKERE-------RQTEKDRDGQR 165
Query: 205 KIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCP 264
+ E T R+ R K + ER+ D DT+
Sbjct: 166 ETE--TERERDREREKQKERETERDR--------------DRQRDTE------------K 197
Query: 265 TMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGD 324
E QT R+ R +K + + + + + + E D
Sbjct: 198 ERERQTD------------------RERDRQRKTQTERQRETDREGERETDRR------- 232
Query: 325 YVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERER---ERDREREEEKKR 380
R+++R+R R +ERDRERDR +R++ER+++R++ER +++ +R E+KKR
Sbjct: 233 ---------RERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 55.1 bits (131), Expect = 2e-07
Identities = 30/73 (41%), Positives = 46/73 (63%), Gaps = 8/73 (10%)
Query: 334 RDKERERYRER-ERDRERDRDRDRERER-------ERDRERERERDREREEEKKRHSYFE 385
R +ER+R RE+ E++R+RDR RDRER R RDRE++ E +R+RE EK++ E
Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRERE 136
Query: 386 KPKVDDEPMDVDK 398
+ + + D D+
Sbjct: 137 RDRGRERERDRDR 149
Score = 53.9 bits (128), Expect = 4e-07
Identities = 30/63 (47%), Positives = 42/63 (66%), Gaps = 2/63 (3%)
Query: 335 DKERERYRERER-DRERDRDRDRERERER-DRERERERDREREEEKKRHSYFEKPKVDDE 392
D++RER R RE+ ++ERDRDR R+RER R ++E R RDRE++ E +R EK K +
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQKGRER 135
Query: 393 PMD 395
D
Sbjct: 136 ERD 138
Score = 45.4 bits (106), Expect = 1e-04
Identities = 26/62 (41%), Positives = 40/62 (64%), Gaps = 2/62 (3%)
Query: 345 ERDRERDRDRDR-ERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGST 403
+R RERDR R++ E+ER+RDR+R+RER R +E+E R+ EK + + +K G
Sbjct: 76 DRQRERDRVREKTEKERDRDRKRDRER-RRKEKETNRNRDREKQTEIERDREREKQKGRE 134
Query: 404 KE 405
+E
Sbjct: 135 RE 136
Score = 38.1 bits (87), Expect = 0.021
Identities = 18/39 (46%), Positives = 30/39 (76%), Gaps = 2/39 (5%)
Query: 343 ERERDRERDRDRDRERERERDR-ERERERDREREEEKKR 380
+ +D + D DR RER+R R++ E+ER+RDR+R+ E++R
Sbjct: 67 QAHKDADGD-DRQRERDRVREKTEKERDRDRKRDRERRR 104
Score = 32.7 bits (73), Expect = 0.90
Identities = 36/161 (22%), Positives = 67/161 (41%), Gaps = 31/161 (19%)
Query: 54 KSRHHEMPREYNEDEDPAARR-----RKKKSYYAKLRQQEIERERELAEKYRDRAKERRD 108
+ R E RE ++D +R R++ K +++E ER+R+ + RD KER
Sbjct: 145 RDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD---RQRDTEKERER 201
Query: 109 GVNKDYEETELISTTANYRAVGPTAEADKSAAEK--RRQLIQESKFLGGDMEHTHLVKGL 166
+++ + T E D+ + RR+ Q + G + +
Sbjct: 202 QTDRERDRQRKTQTERQ-------RETDREGERETDRRRERQRDRDRGKERDR------- 247
Query: 167 DFALLQKVRAEIASKEKEEEELMEKPQ--KETKKDEDPENK 205
++ R E KE+++E E+ + KE K+ ED + K
Sbjct: 248 -----ERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 32.0 bits (71), Expect = 1.5
Identities = 43/183 (23%), Positives = 77/183 (42%), Gaps = 16/183 (8%)
Query: 33 NEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERE 92
N D K R + R + RE D D + R++++ + Q+E E E
Sbjct: 112 NRDREKQTEIERDREREKQKGRERERDRGRERERDRD-REKERERQTEKDRDGQRETETE 170
Query: 93 RELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEAD---KSAAEKRRQLIQE 149
RE ++ R++ KER ++D + T R E D K+ E++R+ +E
Sbjct: 171 RE-RDREREKQKERETERDRDRQRD-----TEKERERQTDRERDRQRKTQTERQRETDRE 224
Query: 150 SKFLGGDME-HTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEF 208
G+ E + D ++ E KE+ ++E ++ +KE K+ + E + E
Sbjct: 225 -----GERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRED 279
Query: 209 KTR 211
K R
Sbjct: 280 KKR 282
Score = 29.6 bits (65), Expect = 7.6
Identities = 36/192 (18%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 19 DVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKK 78
+V P F + +L +++ + +A + + R + RE E E R+R ++
Sbjct: 42 EVTIPLDFSRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRE 101
Query: 79 SYYAKLRQQEIEREREL---AEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEA 135
+ +++E R R+ E RDR +E++ G ++ R G E
Sbjct: 102 R---RRKEKETNRNRDREKQTEIERDREREKQKGRERE-------------RDRGRERER 145
Query: 136 DKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKE 195
D+ ++R + Q K G E T + D ++ E + + ++ +++
Sbjct: 146 DRDREKERER--QTEKDRDGQRE-TETERERDREREKQKERETERDRDRQRDTEKERERQ 202
Query: 196 TKKDEDPENKIE 207
T ++ D + K +
Sbjct: 203 TDRERDRQRKTQ 214
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 71.6 bits (174), Expect = 2e-12
Identities = 48/159 (30%), Positives = 80/159 (50%), Gaps = 16/159 (10%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
RQ R+++ ++ + E ++ E D + T+ R+++R+R R+R+ DRE
Sbjct: 38 RQRDRHRERDRQTDREKERERQKERDRQRQRE--RETERETERQRERQRQRERKRQTDRE 95
Query: 350 RDRDRDRERERERDRERER--------------ERDREREEEKKRHSYFEKPKVDDEPMD 395
RD+DRDRER+RE DR RER ERDRERE +++R ++ + D
Sbjct: 96 RDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
Query: 396 VDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQ 434
++ + +E K +K E + K+ EDKK+
Sbjct: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 67.0 bits (162), Expect = 4e-11
Identities = 32/106 (30%), Positives = 63/106 (59%), Gaps = 2/106 (1%)
Query: 329 TTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
T + R ++R+R+RER+R +R+++R+R++ER+R R+RERE +RE E +++R E+ +
Sbjct: 31 TERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKR 90
Query: 389 VDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQ 434
D D D+ +E + N + G E + ++ D+++
Sbjct: 91 QTDRERDKDRDRERKRETDR--NRERNRKGGRERDKQTERERDRER 134
Score = 55.5 bits (132), Expect = 1e-07
Identities = 27/63 (42%), Positives = 41/63 (65%), Gaps = 9/63 (14%)
Query: 335 DKERERYRERERDRERDRDRDRERERE---------RDRERERERDREREEEKKRHSYFE 385
+++RER RE +R +E +R+RDR+RERE R R+R RERDR+ + EK+R E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 386 KPK 388
+ +
Sbjct: 62 RDR 64
Score = 55.1 bits (131), Expect = 2e-07
Identities = 54/215 (25%), Positives = 89/215 (41%), Gaps = 20/215 (9%)
Query: 343 ERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGS 402
ER+R+R+R+ DR +E ERERDR+RERE ERE RH ++ + D D +K
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERE---NRHRQRDRHRERDRQTDREKERER 58
Query: 403 TKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPATMDDMAVDSDE 462
KE + + E ++ ++K+ D D D +
Sbjct: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTD--------------RERDKDRDRER 104
Query: 463 EVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMSEGRKTRRFKET 522
+ + + + N+KG R +E E ++ + Q K R+ +R+ E
Sbjct: 105 KRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAE- 163
Query: 523 NDKAELDRQWKKISAIIEKRKKMEADGVEVKRPKY 557
+ E ++ KK K KK E E K+ K+
Sbjct: 164 --REERKKERKKERKKERKEKKKEEKRREDKKRKW 196
Score = 41.2 bits (95), Expect = 0.003
Identities = 21/91 (23%), Positives = 52/91 (57%), Gaps = 1/91 (1%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
R+ RN++ +K + +++ E D + R +E +R R+R +RE
Sbjct: 106 RETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAERE 165
Query: 350 RDRDRDRERERERDRERERERDREREEEKKR 380
+R ++R++ER+++R+ +++ ++ RE++K++
Sbjct: 166 -ERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 34.7 bits (78), Expect = 0.24
Identities = 34/151 (22%), Positives = 65/151 (43%), Gaps = 8/151 (5%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVN-- 111
+ RH E R+ + +++ R R+K+ + R++E ERE E ++ R R +ER+ +
Sbjct: 40 RDRHRERDRQTDREKE---RERQKERDRQRQRERETERETE-RQRERQRQRERKRQTDRE 95
Query: 112 --KDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFA 169
KD + T N E+ R +E + + +
Sbjct: 96 RDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETD 155
Query: 170 LLQKVRAEIASKEKEEEELMEKPQKETKKDE 200
++ AE ++KE ++ +K +KE KK+E
Sbjct: 156 RERQRWAEREERKKERKKERKKERKEKKKEE 186
Score = 29.6 bits (65), Expect = 7.6
Identities = 18/75 (24%), Positives = 38/75 (50%), Gaps = 1/75 (1%)
Query: 42 TPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRD 101
T R + + R + RE + + + R+R+++ + R++E +RER+ + +
Sbjct: 108 TDRNRERNRKGGRERDKQTERERDRERE-RQRQRERERQRQRERKRETDRERQRWAEREE 166
Query: 102 RAKERRDGVNKDYEE 116
R KER+ K+ +E
Sbjct: 167 RKKERKKERKKERKE 181
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 71.2 bits (173), Expect = 2e-12
Identities = 37/120 (30%), Positives = 80/120 (66%), Gaps = 6/120 (5%)
Query: 294 RNKKLKKKDKGKLEEKKPP---EADMNIFEDIG--DYVPSTTKTPRDKERERYRERERDR 348
R +K +++++ ++EE++ E + E +G + PS + R++ERE+ RERE++
Sbjct: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEI-REREREKEREREKEL 519
Query: 349 ERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIK 408
E++++++RE+ERE+DRER++E+++E E+E+++ EK + ++ ++++ KEL K
Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQK 579
Score = 62.4 bits (150), Expect = 1e-09
Identities = 36/118 (30%), Positives = 69/118 (58%), Gaps = 10/118 (8%)
Query: 290 RQGTRNKKLKKKDK--GKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERD 347
R+ +KLK+ D+ G LE++ PE + + R+KE E+ +E+ER+
Sbjct: 477 RKAACAEKLKRLDEKLGILEKQPSPEEIRERERE--------KEREREKELEKEQEQERE 528
Query: 348 RERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKE 405
+ER++DR+R++E+E++ E+E+E+ RE E+E+K+ E + ++ ++ K KE
Sbjct: 529 KEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
Score = 48.1 bits (113), Expect = 2e-05
Identities = 25/116 (21%), Positives = 66/116 (56%), Gaps = 12/116 (10%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
++ R K+L+K+ + + E+++ + + + ++ E+E+ ++RE ++E
Sbjct: 511 KEREREKELEKEQEQEREKEREKDRERQ------------QEKEKELEKEQEKQREMEKE 558
Query: 350 RDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKE 405
R +++++E ER++++E+E ++ +E+E+E + EK + EP + + P K+
Sbjct: 559 RKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQ 614
Score = 37.7 bits (86), Expect = 0.028
Identities = 24/108 (22%), Positives = 56/108 (51%), Gaps = 7/108 (6%)
Query: 291 QGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERD--- 347
Q +K ++KD+ + +EK E ++ ++ + K ++KE ER +E+E++
Sbjct: 523 QEQEREKEREKDRERQQEK---EKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQK 579
Query: 348 -RERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPM 394
+E++++ + E+ERE+ E+ R+ E ++ ++EP+
Sbjct: 580 MKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627
Score = 33.9 bits (76), Expect = 0.40
Identities = 32/123 (26%), Positives = 61/123 (49%), Gaps = 10/123 (8%)
Query: 85 RQQEIEREREL-AEKYRDRAKER-RDGVNKDYEETELISTTANYRAVGPTAEADK-SAAE 141
R++E ERE+EL E+ ++R KER +D + +E EL R + + +K E
Sbjct: 509 REKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELE 568
Query: 142 KRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKET--KKD 199
++++ +E + + + L K +K+ +I +E E ++EK + E K+
Sbjct: 569 RQKEKEKELQKMKEQEKECELEKE-----REKLEEKIEPREPNLEPMVEKQESENSCNKE 623
Query: 200 EDP 202
E+P
Sbjct: 624 EEP 626
Score = 33.5 bits (75), Expect = 0.53
Identities = 18/93 (19%), Positives = 48/93 (51%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
R+ R K +++ + + E +K E + ++ + ++KE+E + +E+++E
Sbjct: 527 REKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKE 586
Query: 350 RDRDRDRERERERDRERERERDREREEEKKRHS 382
+ +++RE+ E+ RE + E+++ +S
Sbjct: 587 CELEKEREKLEEKIEPREPNLEPMVEKQESENS 619
Score = 33.5 bits (75), Expect = 0.53
Identities = 21/100 (21%), Positives = 53/100 (53%), Gaps = 12/100 (12%)
Query: 290 RQGTRNKKLKKKDKGK--LEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERD 347
RQ + K+L+K+ + + +E+++ E + + + ++KE ++ +E+E++
Sbjct: 537 RQQEKEKELEKEQEKQREMEKERKQEKEKEL----------ERQKEKEKELQKMKEQEKE 586
Query: 348 RERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
E +++R++ E+ RE E E++E + + E+P
Sbjct: 587 CELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEP 626
Score = 32.0 bits (71), Expect = 1.5
Identities = 27/111 (24%), Positives = 48/111 (43%), Gaps = 13/111 (11%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRER----------ERERDREREEEKKRHSYF 384
++ R+R E ER E R + +R E+ E R+RERE+E++R
Sbjct: 460 ERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKEL 519
Query: 385 EKPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQL 435
EK + + + +K +E K + ++ E +K E +K+L
Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELEKE---QEKQREMEKERKQEKEKEL 567
Score = 30.0 bits (66), Expect = 5.8
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 10/97 (10%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKD 113
K R E E E E + R+K + +++E+E+E+ EK R+ KER K
Sbjct: 511 KEREREKELE-KEQEQEREKEREKDRERQQEKEKELEKEQ---EKQREMEKER-----KQ 561
Query: 114 YEETELISTTANYRAVGPTAEADKSA-AEKRRQLIQE 149
+E EL + + E +K EK R+ ++E
Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKECELEKEREKLEE 598
Score = 30.0 bits (66), Expect = 5.8
Identities = 35/177 (19%), Positives = 73/177 (41%), Gaps = 8/177 (4%)
Query: 27 HQSKLTNEDFRKLLMTPRAAPTSAPPSK-SRHHEMPREYNEDEDPAARRRKKKSYYAKLR 85
+QS +K L P+ SA S+ SR + N + P +R + + K+
Sbjct: 891 NQSACFEAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVT 950
Query: 86 QQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQ 145
+ I+ + + R K +++G + E + Y++ T + ++ +R +
Sbjct: 951 SRCIDSKEPIE---RPEEKPKKEGFIRSSEGPKPEKV---YKSKSETRWGPRPSSNRREE 1004
Query: 146 LIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDP 202
+ G ++ +++ + Q+ E EK E+++ KP+K KKD P
Sbjct: 1005 VNDRPVRRSGPIKKP-VLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPP 1060
Score = 29.3 bits (64), Expect = 9.9
Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 8/60 (13%)
Query: 327 PSTTKTPRDKERERYRERERDRERDRDRDRERERE--------RDRERERERDREREEEK 378
P K + K R+ R R+ DR R RD + ERE+ +E+E EK
Sbjct: 979 PKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEK 1038
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 70.9 bits (172), Expect = 3e-12
Identities = 34/63 (53%), Positives = 48/63 (76%), Gaps = 2/63 (3%)
Query: 328 STTKTPRDKE--RERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFE 385
S + D+E RER RERER+RER+ DR+RE+ERER+RE+ERE+++ERE EK+R E
Sbjct: 223 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 282
Query: 386 KPK 388
+ +
Sbjct: 283 RQR 285
Score = 63.9 bits (154), Expect = 4e-10
Identities = 25/49 (51%), Positives = 44/49 (89%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382
R++ERER +RER++ER+R+R++ERE+E++RERE+ER+RE E ++++ +
Sbjct: 241 REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 289
Score = 61.2 bits (147), Expect = 2e-09
Identities = 24/46 (52%), Positives = 41/46 (89%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
R++E +R RE+ER+RER+++R++E+ERER++ERERE +R+RE+ +
Sbjct: 245 REREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 290
Score = 60.1 bits (144), Expect = 5e-09
Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 8/98 (8%)
Query: 343 ERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGP-G 401
+ E RER+R+R+RERERE DRERE+ER+RERE+E+++ E+ K + ++ +
Sbjct: 230 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 289
Query: 402 STKELI--KSINEKFAGSAGWEG-----TESLKKPEDK 432
KEL+ K++ F A G TE KP ++
Sbjct: 290 REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQ 327
Score = 60.1 bits (144), Expect = 5e-09
Identities = 25/46 (54%), Positives = 39/46 (84%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
R+ +RER +ERER+RE++R++++ERERE++RERE ER RE+ +K
Sbjct: 247 READREREKEREREREKEREQEKEREREKERERELERQREQRAREK 292
Score = 58.5 bits (140), Expect = 2e-08
Identities = 26/44 (59%), Positives = 40/44 (90%), Gaps = 1/44 (2%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERD-REREEE 377
D+ERE+ RERER++ER+++++RERE+ER+RE ER+R+ R RE+E
Sbjct: 250 DREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 293
Score = 35.4 bits (80), Expect = 0.14
Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 54 KSRHHEMPREYN-EDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKER 106
+ R E RE + E E R R+K+ K R++E EREREL + RA+E+
Sbjct: 239 REREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREK 292
Score = 32.7 bits (73), Expect = 0.90
Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYE 115
R E RE E E A R R+K+ + +++E E+ERE EK R+R ER+ +
Sbjct: 235 RERERERE-REREREADREREKEREREREKEREQEKERE-REKERERELERQR--EQRAR 290
Query: 116 ETELISTTANYRAVGPTAE 134
E EL++ A + P AE
Sbjct: 291 EKELLAAKALEPSFLPVAE 309
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 70.9 bits (172), Expect = 3e-12
Identities = 34/63 (53%), Positives = 48/63 (76%), Gaps = 2/63 (3%)
Query: 328 STTKTPRDKE--RERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFE 385
S + D+E RER RERER+RER+ DR+RE+ERER+RE+ERE+++ERE EK+R E
Sbjct: 327 SAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELE 386
Query: 386 KPK 388
+ +
Sbjct: 387 RQR 389
Score = 63.9 bits (154), Expect = 4e-10
Identities = 25/49 (51%), Positives = 44/49 (89%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382
R++ERER +RER++ER+R+R++ERE+E++RERE+ER+RE E ++++ +
Sbjct: 345 REREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
Score = 61.2 bits (147), Expect = 2e-09
Identities = 24/46 (52%), Positives = 41/46 (89%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
R++E +R RE+ER+RER+++R++E+ERER++ERERE +R+RE+ +
Sbjct: 349 REREADREREKEREREREKEREQEKEREREKERERELERQREQRAR 394
Score = 60.1 bits (144), Expect = 5e-09
Identities = 37/98 (37%), Positives = 57/98 (58%), Gaps = 8/98 (8%)
Query: 343 ERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGP-G 401
+ E RER+R+R+RERERE DRERE+ER+RERE+E+++ E+ K + ++ +
Sbjct: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
Query: 402 STKELI--KSINEKFAGSAGWEG-----TESLKKPEDK 432
KEL+ K++ F A G TE KP ++
Sbjct: 394 REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQ 431
Score = 60.1 bits (144), Expect = 5e-09
Identities = 25/46 (54%), Positives = 39/46 (84%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
R+ +RER +ERER+RE++R++++ERERE++RERE ER RE+ +K
Sbjct: 351 READREREKEREREREKEREQEKEREREKERERELERQREQRAREK 396
Score = 58.5 bits (140), Expect = 2e-08
Identities = 26/44 (59%), Positives = 40/44 (90%), Gaps = 1/44 (2%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERD-REREEE 377
D+ERE+ RERER++ER+++++RERE+ER+RE ER+R+ R RE+E
Sbjct: 354 DREREKEREREREKEREQEKEREREKERERELERQREQRAREKE 397
Score = 35.4 bits (80), Expect = 0.14
Identities = 21/54 (38%), Positives = 30/54 (55%), Gaps = 1/54 (1%)
Query: 54 KSRHHEMPREYN-EDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKER 106
+ R E RE + E E R R+K+ K R++E EREREL + RA+E+
Sbjct: 343 REREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREK 396
Score = 32.7 bits (73), Expect = 0.90
Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 4/79 (5%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYE 115
R E RE E E A R R+K+ + +++E E+ERE EK R+R ER+ +
Sbjct: 339 RERERERE-REREREADREREKEREREREKEREQEKERE-REKERERELERQR--EQRAR 394
Query: 116 ETELISTTANYRAVGPTAE 134
E EL++ A + P AE
Sbjct: 395 EKELLAAKALEPSFLPVAE 413
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 70.5 bits (171), Expect = 4e-12
Identities = 43/139 (30%), Positives = 79/139 (56%), Gaps = 9/139 (6%)
Query: 269 QTTLTTNDIVISKLTQIL-SYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVP 327
++ + D++I + +++ + +R+ R ++ +++ K E + E D I +D
Sbjct: 36 RSQIEDRDVLILRGSRVAPAIIRERERQRERERQRKRAKERHR--EKDREIEKD------ 87
Query: 328 STTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
+ RD+ER+R+R+R+R RER DRDRE E ER ERER+RDR+RE++++R E
Sbjct: 88 RDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIG 147
Query: 388 KVDDEPMDVDKGPGSTKEL 406
D ++ +K +E+
Sbjct: 148 IDKDREIETEKDRDREREM 166
Score = 66.6 bits (161), Expect = 6e-11
Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 10/100 (10%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTK---TPRDKERERYRERER 346
RQ R + K + + E+ + E +M E D K T RD++RER RE+E
Sbjct: 140 RQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKE- 198
Query: 347 DRERDRDRDRERERERDRERE------RERDREREEEKKR 380
DRERDRDR +ERE++R RERE +ERDRER+ EK R
Sbjct: 199 DRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
Score = 63.5 bits (153), Expect = 5e-10
Identities = 42/140 (30%), Positives = 79/140 (56%), Gaps = 24/140 (17%)
Query: 290 RQGTRNKKLKKKDKGKLEEKK---------PPEADMNIFEDIGDYVPSTTKTPRDKERER 340
R+ R++K ++KD+ + +++ E D + ++G+ T+ RD+ERER
Sbjct: 126 RERQRDRK-REKDRERQRQREIGIDKDREIETEKDRDREREMGE-----TERYRDRERER 179
Query: 341 YRERE----RDRER-----DRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDD 391
++RE RDRER DR+RDR+R++ER+++R RER+ R+ +K+R ++ K D
Sbjct: 180 QKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRD 239
Query: 392 EPMDVDKGPGSTKELIKSIN 411
+D PG + + +++
Sbjct: 240 RQKAIDCVPGRWEVTVMAVD 259
Score = 42.7 bits (99), Expect = 9e-04
Identities = 50/207 (24%), Positives = 81/207 (39%), Gaps = 42/207 (20%)
Query: 53 SKSRHHEMPREYNEDEDPAARR-----------RKKKSYYAKLRQQEIERERE------- 94
+K RH E RE +D D +R RK++ + + R+ E ER+ E
Sbjct: 73 AKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDR 132
Query: 95 LAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLG 154
EK R+R ++R G++KD E E R +G T E+++Q +E++
Sbjct: 133 KREKDRERQRQREIGIDKD-REIETEKDRDREREMGETERYRDRERERQKQ--RETR--- 186
Query: 155 GDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGR 214
+ R +EKE+ E QKE +KD E + R
Sbjct: 187 ------------------RDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228
Query: 215 NVYRMLFKSKAYERNELFLPGRMAYVV 241
+ R K + ++ +PGR V
Sbjct: 229 DRERQREKDRDRQKAIDCVPGRWEVTV 255
Score = 32.0 bits (71), Expect = 1.5
Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 27/167 (16%)
Query: 52 PSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEK-------YRDRAK 104
P+ R E RE A R ++K +EIE++R+ K +RDR +
Sbjct: 54 PAIIRERERQRERERQRKRAKERHREKD-------REIEKDRDRQRKRDRERQRWRDRDR 106
Query: 105 ERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVK 164
+R ++D ETE R E D+ +R I + + + + +
Sbjct: 107 KRERWGDRD-RETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDR----- 160
Query: 165 GLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTR 211
+ R ++ + E + Q+ET++D D E + E + R
Sbjct: 161 -------DREREMGETERYRDRERERQKQRETRRDRDRERQREKEDR 200
Score = 29.6 bits (65), Expect = 7.6
Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 9/70 (12%)
Query: 44 RAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIE----RERELAE-- 97
R T + R + R+ +D + R+R+++ K R+ E E RERE+ E
Sbjct: 114 RDRETETERQEERERQRDRKREKDRE---RQRQREIGIDKDREIETEKDRDREREMGETE 170
Query: 98 KYRDRAKERR 107
+YRDR +ER+
Sbjct: 171 RYRDRERERQ 180
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 69.3 bits (168), Expect = 9e-12
Identities = 38/76 (50%), Positives = 50/76 (65%), Gaps = 8/76 (10%)
Query: 334 RDKERERYRERERDRERDRDRDRE----RERERDRERERERDREREEEKKRHSYFEKPKV 389
R ER+R R+RER+RERDRDR+RE RE ER RERER+RDR+RE E++R +K +
Sbjct: 42 RHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERER----DKERE 97
Query: 390 DDEPMDVDKGPGSTKE 405
D + D+ KE
Sbjct: 98 TDRHTETDRERQKQKE 113
Score = 66.6 bits (161), Expect = 6e-11
Identities = 32/86 (37%), Positives = 55/86 (63%), Gaps = 6/86 (6%)
Query: 334 RDKERERYRERERDRERDR------DRDRERERERDRERERERDREREEEKKRHSYFEKP 387
R ++RER RER+RDRER++ +R RERER+RDR+RE ER+R++E E RH+ ++
Sbjct: 48 RQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
Query: 388 KVDDEPMDVDKGPGSTKELIKSINEK 413
+ + ++++ +E K + +
Sbjct: 108 RQKQKEREMERVRDREREKQKEMGRE 133
Score = 66.2 bits (160), Expect = 7e-11
Identities = 37/100 (37%), Positives = 57/100 (57%), Gaps = 1/100 (1%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
R+K+ +R ER+R+RERDRDR RE ERERD+ERE +R E + E+++ E +V D
Sbjct: 64 REKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRE 123
Query: 394 MDVDKGPGSTKELIKSINEKFAGSAGWE-GTESLKKPEDK 432
+ K G ++ + + + A E T +K ED+
Sbjct: 124 REKQKEMGRERQTDRETDRERERQAERERETGRERKTEDR 163
Score = 65.9 bits (159), Expect = 1e-10
Identities = 28/54 (51%), Positives = 43/54 (79%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
D+ ER R+R+R+R R+RDRDRERE++ DRE ER+R+RER+ +++R + E+ K
Sbjct: 41 DRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDK 94
Score = 62.0 bits (149), Expect = 1e-09
Identities = 38/89 (42%), Positives = 53/89 (59%), Gaps = 14/89 (15%)
Query: 323 GDYVPSTTKTPRDKERERYRE--RERDR-----------ERDRDRDRERERERDRERERE 369
G + + T+T D++RER RE RERDR ERDR RDRER RERDR+RERE
Sbjct: 7 GRHTHTETET-MDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE 65
Query: 370 RDREREEEKKRHSYFEKPKVDDEPMDVDK 398
+ +RE E++R ++ + + + DK
Sbjct: 66 KQTDREGERQRERERDRDRQRETERERDK 94
Score = 61.6 bits (148), Expect = 2e-09
Identities = 32/79 (40%), Positives = 49/79 (62%), Gaps = 4/79 (5%)
Query: 331 KTPRDKERERYRERERDRERDRDRDRERERERDR----ERERERDREREEEKKRHSYFEK 386
+T R+ ER+R RER+RDR+R+ +R+R++ERE DR +RER++ +ERE E+ R EK
Sbjct: 67 QTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREK 126
Query: 387 PKVDDEPMDVDKGPGSTKE 405
K D+ +E
Sbjct: 127 QKEMGRERQTDRETDRERE 145
Score = 59.7 bits (143), Expect = 7e-09
Identities = 25/75 (33%), Positives = 48/75 (64%)
Query: 331 KTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVD 390
+ K +R+ ER+R R+R+R+R+R+R+RER+++ +RE +R+RE E+ R E +
Sbjct: 33 RAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERER 92
Query: 391 DEPMDVDKGPGSTKE 405
D+ + D+ + +E
Sbjct: 93 DKERETDRHTETDRE 107
Score = 59.3 bits (142), Expect = 9e-09
Identities = 28/48 (58%), Positives = 39/48 (81%), Gaps = 1/48 (2%)
Query: 334 RDKERERYRERERDRE-RDRDRDRERERERDRERERERDREREEEKKR 380
R++ERER RERER RE ++R+R + ERER RE +R+RDR+RE E++R
Sbjct: 165 RERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 58.9 bits (141), Expect = 1e-08
Identities = 39/128 (30%), Positives = 66/128 (51%), Gaps = 18/128 (14%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
R+ + ++ + + E +K E +M D + ++ RER +RE DRE
Sbjct: 90 RERDKERETDRHTETDRERQKQKEREMERVRD------REREKQKEMGRERQTDRETDRE 143
Query: 350 RDRDRDRERE-----------RERDRERERERDRERE-EEKKRHSYFEKPKVDDEPMDVD 397
R+R +RERE RER+RER+RER+R+RE +E++RH+ E+ + + D
Sbjct: 144 RERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRD 203
Query: 398 KGPGSTKE 405
+ S +E
Sbjct: 204 RQRESERE 211
Score = 58.9 bits (141), Expect = 1e-08
Identities = 38/116 (32%), Positives = 65/116 (56%), Gaps = 16/116 (13%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
R +++ +K+ + ++E + E + +++G + +T R++ER+ RERE RE
Sbjct: 100 RHTETDRERQKQKEREMERVRDREREKQ--KEMGRERQTDRETDRERERQAERERETGRE 157
Query: 350 R---DRDRDRERERERDRERERE-----------RDREREEEKKRHSYFEKPKVDD 391
R DR R+RERER+R+RER+RE R+R+RE ++KR E + D
Sbjct: 158 RKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 58.5 bits (140), Expect = 2e-08
Identities = 33/99 (33%), Positives = 56/99 (56%), Gaps = 8/99 (8%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
R+ R+++ +K+ + E ++ E D + + T+ RDKERE R E DRE
Sbjct: 56 RERDRDREREKQTDREGERQRERERDRDRQRE--------TERERDKERETDRHTETDRE 107
Query: 350 RDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
R + ++RE ER RDRERE++++ RE + R + E+ +
Sbjct: 108 RQKQKEREMERVRDREREKQKEMGRERQTDRETDRERER 146
Score = 58.2 bits (139), Expect = 2e-08
Identities = 36/100 (36%), Positives = 51/100 (51%), Gaps = 9/100 (9%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
RQ R + ++ + + E K E D + D + R ++RER +++E RE
Sbjct: 74 RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRE 133
Query: 350 RDRDRDRERERERDRERERE---------RDREREEEKKR 380
R DR+ +RERER ERERE R RERE E+KR
Sbjct: 134 RQTDRETDRERERQAERERETGRERKTEDRHRERERERKR 173
Score = 32.0 bits (71), Expect = 1.5
Identities = 37/162 (22%), Positives = 65/162 (40%), Gaps = 27/162 (16%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKER---RDGVNK 112
R E RE + + D A + + + + RQ++ ER R E+ RDR +E+ R+G +
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNR---ERDRDREREKQTDREGERQ 75
Query: 113 DYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQ 172
E + R E D+ R + Q+ + +ME
Sbjct: 76 RERERDRDRQRETERERDKERETDRHTETDRERQKQKER----EME-------------- 117
Query: 173 KVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGR 214
R +EK++E E+ Q + + D + E + E + GR
Sbjct: 118 --RVRDREREKQKEMGRER-QTDRETDRERERQAERERETGR 156
Score = 30.8 bits (68), Expect = 3.4
Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 5/54 (9%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERR 107
+ + EM RE D + R ++ R++E RER+ +++R+R +ER+
Sbjct: 124 REKQKEMGRERQTDRETDRERERQAE-----RERETGRERKTEDRHRERERERK 172
>gi|10190682 chromobox homolog 8 [Homo sapiens]
Length = 389
Score = 68.6 bits (166), Expect = 1e-11
Identities = 40/84 (47%), Positives = 50/84 (59%), Gaps = 15/84 (17%)
Query: 328 STTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
S+T T E R+R+RDR+RDR+RDRERERER+RERERER+RER
Sbjct: 134 SSTSTSSTCRAEAPRDRDRDRDRDRERDRERERERERERERERERERGTS---------- 183
Query: 388 KVDDEP-----MDVDKGPGSTKEL 406
+VDD+P +GP KEL
Sbjct: 184 RVDDKPSSPGDSSKKRGPKPRKEL 207
Score = 62.8 bits (151), Expect = 8e-10
Identities = 32/70 (45%), Positives = 44/70 (62%)
Query: 331 KTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVD 390
+ PRD++R+R R+RERDRER+R+R+RERERER+RER R ++ S PK
Sbjct: 145 EAPRDRDRDRDRDRERDRERERERERERERERERERGTSRVDDKPSSPGDSSKKRGPKPR 204
Query: 391 DEPMDVDKGP 400
E D + P
Sbjct: 205 KELPDPSQRP 214
Score = 50.4 bits (119), Expect = 4e-06
Identities = 30/78 (38%), Positives = 39/78 (50%), Gaps = 11/78 (14%)
Query: 287 SYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERER 346
S R+G RN L PP + + P RD++RER RERER
Sbjct: 118 SRAREGLRNMGLS-----------PPASSTSTSSTCRAEAPRDRDRDRDRDRERDRERER 166
Query: 347 DRERDRDRDRERERERDR 364
+RER+R+R+RERER R
Sbjct: 167 ERERERERERERERGTSR 184
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 67.4 bits (163), Expect = 3e-11
Identities = 31/55 (56%), Positives = 38/55 (69%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
R +ER R RERERDR RDRDR R RER+RD+ R+RER R+R++ K PK
Sbjct: 2171 RSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPK 2225
Score = 60.1 bits (144), Expect = 5e-09
Identities = 31/62 (50%), Positives = 43/62 (69%), Gaps = 2/62 (3%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERE--RDREREEEKKRHSYFEKPKVDD 391
R KE +R RER R+RER+RDR R+R+R R RER+R+ RDRER ++K S ++ D
Sbjct: 2165 RGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDP 2224
Query: 392 EP 393
+P
Sbjct: 2225 KP 2226
Score = 59.3 bits (142), Expect = 9e-09
Identities = 27/47 (57%), Positives = 36/47 (76%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKR 380
RD+ERE R +E DR R+R R+RERER+R R+R+R R RER+ +K R
Sbjct: 2157 RDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKAR 2203
Score = 58.5 bits (140), Expect = 2e-08
Identities = 27/64 (42%), Positives = 39/64 (60%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPM 394
D+ RER R+R+RE DR ++ +R RER R RERERDR R+ ++ R ++ K D
Sbjct: 2148 DRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRER 2207
Query: 395 DVDK 398
D+
Sbjct: 2208 GRDR 2211
Score = 55.8 bits (133), Expect = 1e-07
Identities = 23/47 (48%), Positives = 37/47 (78%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKR 380
R++E +R +E +R RER R+R+RER+R RDR+R R R+R+R++ + R
Sbjct: 2159 REREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDR 2205
Score = 54.3 bits (129), Expect = 3e-07
Identities = 24/55 (43%), Positives = 38/55 (69%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
R++ER R+RER+ +R ++ DR RER R+RERER+R R+R+ + R +K +
Sbjct: 2149 RNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKAR 2203
Score = 52.8 bits (125), Expect = 8e-07
Identities = 27/76 (35%), Positives = 42/76 (55%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
RD +R R +R RD++ RD DR RER +R+RERE DR +E ++ R + + D
Sbjct: 2127 RDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRR 2186
Query: 394 MDVDKGPGSTKELIKS 409
D D+ ++ K+
Sbjct: 2187 RDRDRSRSRERDRDKA 2202
Score = 52.8 bits (125), Expect = 8e-07
Identities = 26/72 (36%), Positives = 41/72 (56%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
+D R+ R RER RDR+R+ +R +E DR RER R+RERE +++R + + D
Sbjct: 2141 KDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRD 2200
Query: 394 MDVDKGPGSTKE 405
D+ G ++
Sbjct: 2201 KARDRERGRDRK 2212
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 5/58 (8%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDD 391
R+++R R R+R R RERDRD+ R+RER RDR +DR + +E R E + D
Sbjct: 2181 RERDRRRDRDRSRSRERDRDKARDRERGRDR-----KDRSKSKESARDPKPEASRASD 2233
Score = 47.8 bits (112), Expect = 3e-05
Identities = 23/50 (46%), Positives = 29/50 (58%)
Query: 331 KTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKR 380
+ D+ RER R R RERD DR RE +R RD++ R+ DR RE R
Sbjct: 2108 RASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANR 2157
Score = 38.9 bits (89), Expect = 0.013
Identities = 24/93 (25%), Positives = 43/93 (46%)
Query: 345 ERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTK 404
+R RER+R R+ RER+ DR RE +R R+++ + E+ D + D+G +
Sbjct: 2112 DRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDR 2171
Query: 405 ELIKSINEKFAGSAGWEGTESLKKPEDKKQLGD 437
+S N + + S + D+ + D
Sbjct: 2172 SRERSRNRERERDRRRDRDRSRSRERDRDKARD 2204
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 64.7 bits (156), Expect = 2e-10
Identities = 34/74 (45%), Positives = 52/74 (70%), Gaps = 2/74 (2%)
Query: 334 RDKERE-RYRERERDRERDRDRDR-ERERERDRERERERDREREEEKKRHSYFEKPKVDD 391
R++ERE R RERER+RERDR+R+R +RERER+RE ER+++R+R +E+ ++ + D
Sbjct: 406 RERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDR 465
Query: 392 EPMDVDKGPGSTKE 405
+ D D+ KE
Sbjct: 466 QHRDRDREKEREKE 479
Score = 64.3 bits (155), Expect = 3e-10
Identities = 32/48 (66%), Positives = 43/48 (89%), Gaps = 2/48 (4%)
Query: 334 RDKERERYRE-RERDRERDRDRDRERERERDRERERERDREREEEKKR 380
R++ERER RE R+R+RER+R+RDRERER R RERERER+ ER++E++R
Sbjct: 402 RERERERERENRQRERERERERDRERER-RQREREREREHERDKERQR 448
Score = 60.8 bits (146), Expect = 3e-09
Identities = 35/74 (47%), Positives = 45/74 (60%), Gaps = 4/74 (5%)
Query: 323 GDYVPSTTKTPRDKERERYRERERDRERD-RDRDRERERERDRERER---ERDREREEEK 378
G Y + + YRERER+RER+ R R+RERERERDRERER ER+RERE E+
Sbjct: 383 GQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQREREREREHER 442
Query: 379 KRHSYFEKPKVDDE 392
+ K + + E
Sbjct: 443 DKERQRRKEEWERE 456
Score = 59.7 bits (143), Expect = 7e-09
Identities = 31/73 (42%), Positives = 45/73 (61%), Gaps = 3/73 (4%)
Query: 335 DKERERYRERERDRERDR---DRDRERERERDRERERERDREREEEKKRHSYFEKPKVDD 391
+++RER RERERDRER+R +R+RERE ERD+ER+R ++ E KR + + D
Sbjct: 412 NRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRD 471
Query: 392 EPMDVDKGPGSTK 404
+ +K G K
Sbjct: 472 REKEREKEKGKPK 484
Score = 56.6 bits (135), Expect = 6e-08
Identities = 31/70 (44%), Positives = 46/70 (65%), Gaps = 11/70 (15%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDR-ERER---------ERDREREEEKKRHSY 383
RD+ERER R+RER+RER+ +RD+ER+R ++ ERER RDR+RE+E+++
Sbjct: 423 RDRERER-RQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKG 481
Query: 384 FEKPKVDDEP 393
KP+ P
Sbjct: 482 KPKPRSPQPP 491
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/49 (46%), Positives = 35/49 (71%), Gaps = 2/49 (4%)
Query: 334 RDKERERYRERERDRERDRD-RDRERERERD-RERERERDREREEEKKR 380
R + E +R + + E + R+RERERER+ R+RERER+RER+ E++R
Sbjct: 381 RGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERDRERER 429
Score = 30.0 bits (66), Expect = 5.8
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 63 EYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETE 118
+Y E E R +++ + RQ+E ERERE RDR +ERR + E E
Sbjct: 391 QYTETEPYHNYRERERERERENRQRERERERE-----RDRERERRQREREREREHE 441
Score = 29.3 bits (64), Expect = 9.9
Identities = 14/65 (21%), Positives = 36/65 (55%), Gaps = 4/65 (6%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKD 113
++R E RE D + R+R+++ + R+ E ++ER+ ++ +R + +RD ++
Sbjct: 411 ENRQRERERERERDRERERRQRERE----REREHERDKERQRRKEEWERERAKRDEKDRQ 466
Query: 114 YEETE 118
+ + +
Sbjct: 467 HRDRD 471
Score = 29.3 bits (64), Expect = 9.9
Identities = 15/57 (26%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNK 112
R E RE + D +RRK++ + + R + E++R+ ++ R++ +E+ G K
Sbjct: 430 RQREREREREHERDKERQRRKEE--WERERAKRDEKDRQHRDRDREKEREKEKGKPK 484
>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
Length = 520
Score = 63.5 bits (153), Expect = 5e-10
Identities = 30/51 (58%), Positives = 39/51 (76%), Gaps = 2/51 (3%)
Query: 327 PSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEE 377
PS T K+ + Y RE+DR+R+RDRDRER+R+RDRERER R+RERE +
Sbjct: 368 PSLVDT--SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD 416
Score = 54.3 bits (129), Expect = 3e-07
Identities = 22/33 (66%), Positives = 31/33 (93%)
Query: 348 RERDRDRDRERERERDRERERERDREREEEKKR 380
RE+DRDR+R+R+RERDR+R+RER+R RE E++R
Sbjct: 383 REKDRDRERDRDRERDRDRDRERERTRERERER 415
Score = 54.3 bits (129), Expect = 3e-07
Identities = 30/68 (44%), Positives = 39/68 (57%), Gaps = 20/68 (29%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDR--------------------ERERERDRE 373
RD+ER+R RER+RDR+R+R+R RERERERD ER ER R
Sbjct: 387 RDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA 446
Query: 374 REEEKKRH 381
E+++RH
Sbjct: 447 SREKEERH 454
Score = 44.3 bits (103), Expect = 3e-04
Identities = 18/33 (54%), Positives = 27/33 (81%)
Query: 354 RDRERERERDRERERERDREREEEKKRHSYFEK 386
R+++R+RERDR+RER+RDR+RE E+ R E+
Sbjct: 383 REKDRDRERDRDRERDRDRDRERERTRERERER 415
Score = 38.5 bits (88), Expect = 0.016
Identities = 16/45 (35%), Positives = 29/45 (64%)
Query: 347 DRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDD 391
D + D RE++RDRER+R+R+R+R+ +++R E+ + D
Sbjct: 372 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD 416
Score = 38.5 bits (88), Expect = 0.016
Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 324 DYVPSTTKTPRDKERERYRE-RERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382
D+ P+ + D+ER RYRE ER ER R + ER R+R R RE++ R + + +S
Sbjct: 416 DHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNS 474
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 351 DRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSI 410
D + + R+++R+RERDR+RE ++ R E+ + + + D P T + S
Sbjct: 372 DTSKQWDYYARREKDRDRERDRDRERDRDRDR--ERERTRERERERDHSP--TPSVFNSD 427
Query: 411 NEKFA----GSAGWEGTESLKKPEDK 432
E++ G+E + ++ E++
Sbjct: 428 EERYRYREYAERGYERHRASREKEER 453
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSY-YAKLRQQEIERERELAEKYRDRAKERRDGVNK 112
+ R E RE + P+ ++ Y Y + ++ ER R EK +R +ERR ++
Sbjct: 405 RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREK-EERHRERR---HR 460
Query: 113 DYEETELISTTANYRAVGPTAEADKSAAEKRRQ 145
+ EET S+ +N R + E D K ++
Sbjct: 461 EKEETRHKSSRSNSRRRHESEEGDSHRRHKHKK 493
>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
Length = 588
Score = 63.5 bits (153), Expect = 5e-10
Identities = 30/51 (58%), Positives = 39/51 (76%), Gaps = 2/51 (3%)
Query: 327 PSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEE 377
PS T K+ + Y RE+DR+R+RDRDRER+R+RDRERER R+RERE +
Sbjct: 436 PSLVDT--SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD 484
Score = 54.3 bits (129), Expect = 3e-07
Identities = 22/33 (66%), Positives = 31/33 (93%)
Query: 348 RERDRDRDRERERERDRERERERDREREEEKKR 380
RE+DRDR+R+R+RERDR+R+RER+R RE E++R
Sbjct: 451 REKDRDRERDRDRERDRDRDRERERTRERERER 483
Score = 54.3 bits (129), Expect = 3e-07
Identities = 30/68 (44%), Positives = 39/68 (57%), Gaps = 20/68 (29%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDR--------------------ERERERDRE 373
RD+ER+R RER+RDR+R+R+R RERERERD ER ER R
Sbjct: 455 RDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA 514
Query: 374 REEEKKRH 381
E+++RH
Sbjct: 515 SREKEERH 522
Score = 44.3 bits (103), Expect = 3e-04
Identities = 18/33 (54%), Positives = 27/33 (81%)
Query: 354 RDRERERERDRERERERDREREEEKKRHSYFEK 386
R+++R+RERDR+RER+RDR+RE E+ R E+
Sbjct: 451 REKDRDRERDRDRERDRDRDRERERTRERERER 483
Score = 38.5 bits (88), Expect = 0.016
Identities = 16/45 (35%), Positives = 29/45 (64%)
Query: 347 DRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDD 391
D + D RE++RDRER+R+R+R+R+ +++R E+ + D
Sbjct: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD 484
Score = 38.5 bits (88), Expect = 0.016
Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 324 DYVPSTTKTPRDKERERYRE-RERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382
D+ P+ + D+ER RYRE ER ER R + ER R+R R RE++ R + + +S
Sbjct: 484 DHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNS 542
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 351 DRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSI 410
D + + R+++R+RERDR+RE ++ R E+ + + + D P T + S
Sbjct: 440 DTSKQWDYYARREKDRDRERDRDRERDRDRDR--ERERTRERERERDHSP--TPSVFNSD 495
Query: 411 NEKFA----GSAGWEGTESLKKPEDK 432
E++ G+E + ++ E++
Sbjct: 496 EERYRYREYAERGYERHRASREKEER 521
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSY-YAKLRQQEIERERELAEKYRDRAKERRDGVNK 112
+ R E RE + P+ ++ Y Y + ++ ER R EK +R +ERR ++
Sbjct: 473 RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREK-EERHRERR---HR 528
Query: 113 DYEETELISTTANYRAVGPTAEADKSAAEKRRQ 145
+ EET S+ +N R + E D K ++
Sbjct: 529 EKEETRHKSSRSNSRRRHESEEGDSHRRHKHKK 561
>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
Length = 594
Score = 63.5 bits (153), Expect = 5e-10
Identities = 30/51 (58%), Positives = 39/51 (76%), Gaps = 2/51 (3%)
Query: 327 PSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEE 377
PS T K+ + Y RE+DR+R+RDRDRER+R+RDRERER R+RERE +
Sbjct: 442 PSLVDT--SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD 490
Score = 54.3 bits (129), Expect = 3e-07
Identities = 22/33 (66%), Positives = 31/33 (93%)
Query: 348 RERDRDRDRERERERDRERERERDREREEEKKR 380
RE+DRDR+R+R+RERDR+R+RER+R RE E++R
Sbjct: 457 REKDRDRERDRDRERDRDRDRERERTRERERER 489
Score = 54.3 bits (129), Expect = 3e-07
Identities = 30/68 (44%), Positives = 39/68 (57%), Gaps = 20/68 (29%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDR--------------------ERERERDRE 373
RD+ER+R RER+RDR+R+R+R RERERERD ER ER R
Sbjct: 461 RDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA 520
Query: 374 REEEKKRH 381
E+++RH
Sbjct: 521 SREKEERH 528
Score = 44.3 bits (103), Expect = 3e-04
Identities = 18/33 (54%), Positives = 27/33 (81%)
Query: 354 RDRERERERDRERERERDREREEEKKRHSYFEK 386
R+++R+RERDR+RER+RDR+RE E+ R E+
Sbjct: 457 REKDRDRERDRDRERDRDRDRERERTRERERER 489
Score = 38.5 bits (88), Expect = 0.016
Identities = 16/45 (35%), Positives = 29/45 (64%)
Query: 347 DRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDD 391
D + D RE++RDRER+R+R+R+R+ +++R E+ + D
Sbjct: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD 490
Score = 38.5 bits (88), Expect = 0.016
Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 324 DYVPSTTKTPRDKERERYRE-RERDRERDRDRDRERERERDRERERERDREREEEKKRHS 382
D+ P+ + D+ER RYRE ER ER R + ER R+R R RE++ R + + +S
Sbjct: 490 DHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNS 548
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 8/86 (9%)
Query: 351 DRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSI 410
D + + R+++R+RERDR+RE ++ R E+ + + + D P T + S
Sbjct: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDR--ERERTRERERERDHSP--TPSVFNSD 501
Query: 411 NEKFA----GSAGWEGTESLKKPEDK 432
E++ G+E + ++ E++
Sbjct: 502 EERYRYREYAERGYERHRASREKEER 527
Score = 32.0 bits (71), Expect = 1.5
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSY-YAKLRQQEIERERELAEKYRDRAKERRDGVNK 112
+ R E RE + P+ ++ Y Y + ++ ER R EK +R +ERR ++
Sbjct: 479 RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREK-EERHRERR---HR 534
Query: 113 DYEETELISTTANYRAVGPTAEADKSAAEKRRQ 145
+ EET S+ +N R + E D K ++
Sbjct: 535 EKEETRHKSSRSNSRRRHESEEGDSHRRHKHKK 567
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 63.2 bits (152), Expect = 6e-10
Identities = 35/79 (44%), Positives = 49/79 (62%), Gaps = 3/79 (3%)
Query: 303 KGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERER 362
+ + +K+ + DM + +D + R + RER RERERDR RD RDRER+R R
Sbjct: 627 EARYRDKRVHDYDMRV-DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGR 685
Query: 363 DRERERER--DREREEEKK 379
DRERERER DR+R+ ++
Sbjct: 686 DRERERERLCDRDRDRGER 704
Score = 53.9 bits (128), Expect = 4e-07
Identities = 26/50 (52%), Positives = 36/50 (72%), Gaps = 2/50 (4%)
Query: 333 PRDKERERYRERERDRERDRDRDR--ERERERDRERERERDREREEEKKR 380
PR+++RER R+R RD RDR+RDR +RERER+R +R+RDR +R
Sbjct: 660 PRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 709
Score = 50.1 bits (118), Expect = 5e-06
Identities = 21/43 (48%), Positives = 31/43 (72%)
Query: 346 RDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
R R R+RDR+RER+R RD R+RERDR R+ E++R ++ +
Sbjct: 657 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDR 699
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPM 394
+++ E E E D E D + D + E E + E E E + E EEE+ ++ + ++
Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265
Query: 395 DVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLG 436
+ S E + + +G +G++ KK E K+ G
Sbjct: 266 TRSEASDSGSESVSFTDGSVRSGSGTDGSDE-KKKERKRARG 306
Score = 40.0 bits (92), Expect = 0.006
Identities = 18/44 (40%), Positives = 28/44 (63%)
Query: 352 RDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMD 395
R R RER+RER+R+R R+ R+RE ++ R E+ ++ D D
Sbjct: 657 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRD 700
Score = 36.6 bits (83), Expect = 0.062
Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 333 PRDKERERYRERERDRERDRDRDRERERERDRERERERD--REREEEKKRHSYFEKPKVD 390
P D+ + Y+ + R + R + R R R RE RD R R E+ H+ +KP++
Sbjct: 475 PPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYDIHNSRKKPRI- 533
Query: 391 DEPMDVDKGPGSTKE-LIKSINEKFAG 416
D P + + PG K+ + ++ +F+G
Sbjct: 534 DYPPEFHQRPGYLKDPRYQEVDRRFSG 560
Score = 36.6 bits (83), Expect = 0.062
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 356 RERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPG 401
R R RERDRERER+R R+ +++R ++ + + D D+ G
Sbjct: 657 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 702
Score = 32.7 bits (73), Expect = 0.90
Identities = 17/73 (23%), Positives = 33/73 (45%)
Query: 320 EDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
E+ G + + D++ E E D + D E E + + + E + D E EEE++
Sbjct: 177 EEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEE 236
Query: 380 RHSYFEKPKVDDE 392
E+ + ++E
Sbjct: 237 EEEEEEEEEEEEE 249
Score = 31.2 bits (69), Expect = 2.6
Identities = 33/171 (19%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 326 VPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRE---RERERDREREEEKKRHS 382
V + K+ + + E Y+ ER++ D DR RE + E+ R+ + +R +
Sbjct: 85 VSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRA 144
Query: 383 YFEKPKVDDE-PMDVDKGPGSTKELIK-SINEKFAGSAGWEGTESLKKPEDKKQLGDFFG 440
P + ++VD+ + + K +N + GS G+ + + G
Sbjct: 145 KSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEG 204
Query: 441 MSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSE 491
+ E D + DEEVD ++ ++ + + +EEY +
Sbjct: 205 VEEDVEEDEEVEED---AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Score = 30.8 bits (68), Expect = 3.4
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 11/81 (13%)
Query: 45 AAPTSAPPSKSRHHEMPRE----------YNEDEDPAARRRKKKSYYAKLRQQEIERERE 94
A P A P S HH +P E Y+ D RR + + R +E +RERE
Sbjct: 609 APPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERE 668
Query: 95 LAEKYRDRAKERRDGVNKDYE 115
++ RD ++R +D E
Sbjct: 669 -RDRPRDNRRDRERDRGRDRE 688
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 63.2 bits (152), Expect = 6e-10
Identities = 35/79 (44%), Positives = 49/79 (62%), Gaps = 3/79 (3%)
Query: 303 KGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERER 362
+ + +K+ + DM + +D + R + RER RERERDR RD RDRER+R R
Sbjct: 645 EARYRDKRVHDYDMRV-DDFLRRTQAVVSGRRSRPRERDRERERDRPRDNRRDRERDRGR 703
Query: 363 DRERERER--DREREEEKK 379
DRERERER DR+R+ ++
Sbjct: 704 DRERERERLCDRDRDRGER 722
Score = 53.9 bits (128), Expect = 4e-07
Identities = 26/50 (52%), Positives = 36/50 (72%), Gaps = 2/50 (4%)
Query: 333 PRDKERERYRERERDRERDRDRDR--ERERERDRERERERDREREEEKKR 380
PR+++RER R+R RD RDR+RDR +RERER+R +R+RDR +R
Sbjct: 678 PRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRGERGRYRR 727
Score = 50.1 bits (118), Expect = 5e-06
Identities = 21/43 (48%), Positives = 31/43 (72%)
Query: 346 RDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
R R R+RDR+RER+R RD R+RERDR R+ E++R ++ +
Sbjct: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDR 717
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 1/102 (0%)
Query: 335 DKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPM 394
+++ E E E D E D + D + E E + E E E + E EEE+ ++ + ++
Sbjct: 206 EEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYD 265
Query: 395 DVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLG 436
+ S E + + +G +G++ KK E K+ G
Sbjct: 266 TRSEASDSGSESVSFTDGSVRSGSGTDGSDE-KKKERKRARG 306
Score = 40.0 bits (92), Expect = 0.006
Identities = 18/44 (40%), Positives = 28/44 (63%)
Query: 352 RDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMD 395
R R RER+RER+R+R R+ R+RE ++ R E+ ++ D D
Sbjct: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRD 718
Score = 36.6 bits (83), Expect = 0.062
Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 333 PRDKERERYRERERDRERDRDRDRERERERDRERERERD--REREEEKKRHSYFEKPKVD 390
P D+ + Y+ + R + R + R R R RE RD R R E+ H+ +KP++
Sbjct: 493 PPDESIDLYQVIHKMRHKRRMHSQPRSRGRPSRREPVRDVGRRRPEDYDIHNSRKKPRI- 551
Query: 391 DEPMDVDKGPGSTKE-LIKSINEKFAG 416
D P + + PG K+ + ++ +F+G
Sbjct: 552 DYPPEFHQRPGYLKDPRYQEVDRRFSG 578
Score = 36.6 bits (83), Expect = 0.062
Identities = 17/46 (36%), Positives = 27/46 (58%)
Query: 356 RERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPG 401
R R RERDRERER+R R+ +++R ++ + + D D+ G
Sbjct: 675 RSRPRERDRERERDRPRDNRRDRERDRGRDRERERERLCDRDRDRG 720
Score = 32.7 bits (73), Expect = 0.90
Identities = 17/73 (23%), Positives = 33/73 (45%)
Query: 320 EDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
E+ G + + D++ E E D + D E E + + + E + D E EEE++
Sbjct: 177 EEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEE 236
Query: 380 RHSYFEKPKVDDE 392
E+ + ++E
Sbjct: 237 EEEEEEEEEEEEE 249
Score = 31.2 bits (69), Expect = 2.6
Identities = 33/171 (19%), Positives = 67/171 (39%), Gaps = 8/171 (4%)
Query: 326 VPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRE---RERERDREREEEKKRHS 382
V + K+ + + E Y+ ER++ D DR RE + E+ R+ + +R +
Sbjct: 85 VSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRA 144
Query: 383 YFEKPKVDDE-PMDVDKGPGSTKELIK-SINEKFAGSAGWEGTESLKKPEDKKQLGDFFG 440
P + ++VD+ + + K +N + GS G+ + + G
Sbjct: 145 KSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEG 204
Query: 441 MSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSE 491
+ E D + DEEVD ++ ++ + + +EEY +
Sbjct: 205 VEEDVEEDEEVEED---AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Score = 30.8 bits (68), Expect = 3.4
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 11/81 (13%)
Query: 45 AAPTSAPPSKSRHHEMPRE----------YNEDEDPAARRRKKKSYYAKLRQQEIERERE 94
A P A P S HH +P E Y+ D RR + + R +E +RERE
Sbjct: 627 APPPQAHPPYSGHHPVPHEARYRDKRVHDYDMRVDDFLRRTQAVVSGRRSRPRERDRERE 686
Query: 95 LAEKYRDRAKERRDGVNKDYE 115
++ RD ++R +D E
Sbjct: 687 -RDRPRDNRRDRERDRGRDRE 706
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 62.0 bits (149), Expect = 1e-09
Identities = 36/101 (35%), Positives = 57/101 (56%), Gaps = 2/101 (1%)
Query: 283 TQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYR 342
+QI+ + K ++K + + EE++ E + + + + +ER+R R
Sbjct: 1232 SQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRER 1291
Query: 343 ERERDRER-DRDRDRERERERDRERERERDREREEEKKRHS 382
ERER+R+R DRDRDRER+RER RER+R RD +R + S
Sbjct: 1292 ERERERDRGDRDRDRERDRERGRERDR-RDTKRHSRSRSRS 1331
Score = 58.2 bits (139), Expect = 2e-08
Identities = 57/205 (27%), Positives = 90/205 (43%), Gaps = 22/205 (10%)
Query: 174 VRAEIASKEKEEEELMEKPQKETKKDEDPEN---KIEFKTRLGRNVYRMLFKSKAYERNE 230
VR + A +E+E E E+ + E + D D + ++R R R K K E+ E
Sbjct: 1142 VREQWAEREREMER-RERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKE 1200
Query: 231 LFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLR 290
A ++D L R P + T+ ++ K + +
Sbjct: 1201 KAQEEPPAKLLD------------DLFRKTKAAPCI--YWLPLTDSQIVQKEAERAERAK 1246
Query: 291 QGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERER-DRE 349
+ + +K +++++ K EK EA+ + RD+ERER RER+R DR+
Sbjct: 1247 EREKRRKEQEEEEQKEREK---EAERERNRQLEREKRREHSRERDRERERERERDRGDRD 1303
Query: 350 RDRDRDRERERERDRERERERDRER 374
RDR+RDRER RERDR + R R
Sbjct: 1304 RDRERDRERGRERDRRDTKRHSRSR 1328
Score = 58.2 bits (139), Expect = 2e-08
Identities = 30/60 (50%), Positives = 41/60 (68%), Gaps = 5/60 (8%)
Query: 336 KERERYRERERDRERDRDRDRERERERDRERERER-----DREREEEKKRHSYFEKPKVD 390
KERE+ ERER+R+ +R++ RE RERDRERERER DR+R+ E+ R E+ + D
Sbjct: 1261 KEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRD 1320
Score = 55.5 bits (132), Expect = 1e-07
Identities = 34/116 (29%), Positives = 65/116 (56%), Gaps = 7/116 (6%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGD-----YVPSTTKTPRDKERERYRER 344
++ ++K+ K + K K +E+ P + ++F ++P T KE ER ER
Sbjct: 1186 KERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAER-AER 1244
Query: 345 ERDRERDR-DRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKG 399
++RE+ R +++ E ++ER++E ERER+R+ E EK+R E+ + + + D+G
Sbjct: 1245 AKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRG 1300
Score = 45.1 bits (105), Expect = 2e-04
Identities = 26/64 (40%), Positives = 37/64 (57%), Gaps = 8/64 (12%)
Query: 338 RERYRERERDRER------DRDRDRERERERDRERERERDREREE--EKKRHSYFEKPKV 389
RE++ ERER+ ER +R+ DR++ RE R R R RDR R+E + K +K K
Sbjct: 1143 REQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKA 1202
Query: 390 DDEP 393
+EP
Sbjct: 1203 QEEP 1206
Score = 40.8 bits (94), Expect = 0.003
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 17/205 (8%)
Query: 35 DFRKLLMTPRAAPTSAPPS---KSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIER 91
D+ + L+ R + T + H P + P A +R+++ +R+Q ER
Sbjct: 1093 DYHRGLLVDRPSETKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQER---AVREQWAER 1149
Query: 92 ERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQE-- 149
ERE+ + R+R + R+ E + + R A++ + +EK+ + +E
Sbjct: 1150 EREM--ERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPP 1207
Query: 150 SKFLGGDMEHTHLVKGL------DFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPE 203
+K L T + D ++QK AE A + KE E+ ++ ++E +K+ + E
Sbjct: 1208 AKLLDDLFRKTKAAPCIYWLPLTDSQIVQK-EAERAERAKEREKRRKEQEEEEQKEREKE 1266
Query: 204 NKIEFKTRLGRNVYRMLFKSKAYER 228
+ E +L R R + + ER
Sbjct: 1267 AERERNRQLEREKRREHSRERDRER 1291
Score = 40.0 bits (92), Expect = 0.006
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 330 TKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEE 377
T++ R+ +R++ RE R R R RDR R +ER + +E++ E+ + +EE
Sbjct: 1159 TRSEREWDRDKVREGPRSRSRSRDR-RRKERAKSKEKKSEKKEKAQEE 1205
Score = 37.7 bits (86), Expect = 0.028
Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKD 113
K R E RE N + RR + + R++E ERER+ ++ RDR ++R G +D
Sbjct: 1261 KEREKEAERERNRQLEREKRREHSRE---RDRERERERERDRGDRDRDRERDRERGRERD 1317
Query: 114 YEETE 118
+T+
Sbjct: 1318 RRDTK 1322
Score = 37.4 bits (85), Expect = 0.036
Identities = 54/231 (23%), Positives = 82/231 (35%), Gaps = 31/231 (13%)
Query: 327 PSTTKTPRDKERERYRERERD-RERDRDRDRERERERDRERERERDREREEEKKRHSYFE 385
P P R RE+ER RE+ +R+RE ER ERE DR++ E R
Sbjct: 1121 PPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRS 1180
Query: 386 KPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSY 445
+ + KE KS +K E E ++ K L D F + +
Sbjct: 1181 RDR-------------RRKERAKSKEKKS------EKKEKAQEEPPAKLLDDLFRKTKAA 1221
Query: 446 AECY--PATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAA 503
Y P T + E + +K + +K QEE + KEA +
Sbjct: 1222 PCIYWLPLTDSQIVQKEAERAERAKEREKRRK---------EQEEEEQKEREKEAERERN 1272
Query: 504 FQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGVEVKR 554
Q + R +E + E DR + ++ + E D + KR
Sbjct: 1273 RQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKR 1323
Score = 33.9 bits (76), Expect = 0.40
Identities = 51/247 (20%), Positives = 93/247 (37%), Gaps = 17/247 (6%)
Query: 136 DKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKE 195
D S + K +L E L G V L AL Q+ A+ K + L E
Sbjct: 52 DPSTSRKMAEL--EEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLE 109
Query: 196 T-KKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAY----VVDLDDEYADT 250
+K P + +++G + + F + E+ + L R+ +L++ A++
Sbjct: 110 NLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAES 169
Query: 251 DIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKK 310
+ A + Q++L ++ +S R R ++KG +++K
Sbjct: 170 EDEMIHPEGVASLLPPDFQSSLERPELELS---------RHSPRKSSSISEEKGDSDDEK 220
Query: 311 PPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDR-DRDRERERERDRERERE 369
P + + ++ + E E +E R R DR+ + E E + E E E
Sbjct: 221 PRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEE 280
Query: 370 RDREREE 376
D E EE
Sbjct: 281 EDDEEEE 287
Score = 32.0 bits (71), Expect = 1.5
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 14/100 (14%)
Query: 312 PEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRE------ 365
P +I E+ GD S + PR ER R R+ + + + E E D+E
Sbjct: 203 PRKSSSISEEKGD---SDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNL 259
Query: 366 -----RERERDREREEEKKRHSYFEKPKVDDEPMDVDKGP 400
R + + E EEE++ E+ + DDE + P
Sbjct: 260 RVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAP 299
Score = 30.0 bits (66), Expect = 5.8
Identities = 20/60 (33%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELA-EKYRDRAKER-RDGVNKD 113
R E + E E+ + R+K++ + RQ E E+ RE + E+ R+R +ER RD ++D
Sbjct: 1244 RAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRD 1303
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 61.6 bits (148), Expect = 2e-09
Identities = 86/392 (21%), Positives = 173/392 (44%), Gaps = 46/392 (11%)
Query: 54 KSRHHEMPREYNED------------EDPAARRR----KKKSYYAKLRQQEIERERELAE 97
K R E R+Y +D E+P RRR KK +L+Q+E + RE E
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 98 KYRDRAKER--RDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGG 155
K R + ER R EE +L+ R + E ++ E+ +L QE + L G
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRL---QERERQYREEE-ELQQEEEQLLG 1065
Query: 156 DMEHTHLVKGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRN 215
+ T + L+ ++ R E +++EE+ L E+P+K +++ + + + E L +
Sbjct: 1066 EERETRRRQELE----RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE--EELQQE 1119
Query: 216 VYRMLFKSKAYERN-ELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTT 274
++L + + R EL R V ++E + P R + + E +
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 275 NDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIG-DYVPSTTKTP 333
+ ++ + + R+ R ++ +++++ + +++K D + D+ + P
Sbjct: 1180 EEQLLREEQE----KRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 334 RD-------KERERYRERERDRERDRDRDRERER--ERDRERERERDREREEEKKRHSYF 384
RD +E E++R+ E + RDR ++ + +ER+RE++R R +++ RH
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 385 EKPKVDDEPMDV---DKGPGSTKELIKSINEK 413
E+ +E + D+ K+L++ E+
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREE 1327
Score = 58.5 bits (140), Expect = 2e-08
Identities = 74/352 (21%), Positives = 145/352 (41%), Gaps = 58/352 (16%)
Query: 56 RHHEMPREYNEDED------------PAARRRKKKSYYAKLRQQEIERERELAEKYRDRA 103
R E+ R+Y ++E+ P RRR+++ + ++E+++E E + +R
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR-EEEELQQEEEQLLR-EERE 1129
Query: 104 KERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLV 163
K RR + + Y E E + E +K ++ + +E + L E L+
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLL---REEPEKRRRQELERQYREEEEL--QQEEEQLL 1184
Query: 164 KGLDFALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKS 223
+ +K R E + +EEEEL + +K+ +DED + ++++ + + +
Sbjct: 1185 REEQ----EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE--NAVRDN 1238
Query: 224 KAY---ERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVIS 280
K Y NE F R L D + D+ L+ + + + + D
Sbjct: 1239 KVYCKGRENEQF---RQLEDSQLRDRQSQQDLQH-LLGEQQERDREQERRRWQQRDRHFP 1294
Query: 281 KLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERER 340
+ Q+ + K+ K++D+ EEK+ R++ E+
Sbjct: 1295 EEEQL-----EREEQKEAKRRDRKSQEEKQ---------------------LLREEREEK 1328
Query: 341 YRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDE 392
R +E DR+ + +ERE R +ERDR+ EE+ RH + +++E
Sbjct: 1329 RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Score = 52.8 bits (125), Expect = 8e-07
Identities = 68/340 (20%), Positives = 145/340 (42%), Gaps = 47/340 (13%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYE 115
R E R++ E+E R+++++ + + +Q + + + RDR + + ++ E
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQERE 1568
Query: 116 ETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVR 175
E +L + + + +K R+ QE KF+ D + +G Q++R
Sbjct: 1569 EQQLSRQERDRKF--------RLEEQKVRRQEQERKFME-DEQQLRRQEGQ-----QQLR 1614
Query: 176 AEIASKEKEEEELM-EKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKS----KAYERNE 230
E K +E+E+L+ E+ +++ + E +E + +L R + K E +
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674
Query: 231 LFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLR 290
L G + + + + L R + + ++ + L ++ + + LR
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL--ERKFREEEQLR 1732
Query: 291 QGTRNKKLKKKDKGKL---EEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERD 347
Q T ++L+++++ + EE+ PE +E ++ R +ERD
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPE----------------------REEQQLRRQERD 1770
Query: 348 RERDRDRDRERERERDRERERERDRE-REEEKKRHSYFEK 386
R+ + +ERE + R +E DR+ REEE+ R E+
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Score = 52.0 bits (123), Expect = 1e-06
Identities = 75/394 (19%), Positives = 155/394 (39%), Gaps = 40/394 (10%)
Query: 2 PERDSEPFSNPLAPDGHDVDDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMP 61
PE+++ N + G + + S+L + ++ L + R
Sbjct: 1229 PEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQ 1288
Query: 62 REYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELIS 121
R+ + E+ R ++K AK R ++ + E++L + R+ + R++ K EE +L+
Sbjct: 1289 RDRHFPEEEQLEREEQKE--AKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Query: 122 TTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASK 181
++ RRQ ++ KF ++ H + + R E K
Sbjct: 1347 --------------EREEQPLRRQE-RDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Query: 182 EKEEEELMEKPQKETKKDEDPENKI-EFKTRLGRNVYRMLFKS-----KAYERNELFLPG 235
+EE+ + ++E + +D + K E + +L R F+ + ER FL
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE 1451
Query: 236 RMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRN 295
+ ++ + + L++ + E Q D K + LR+ R+
Sbjct: 1452 EQQLRQERHRKFREEE---QLLQERE-----EQQLHRQERD---RKFLEEEQQLRRQERD 1500
Query: 296 KKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRD 355
+K ++ +E + E + E+ + +E ++ R +ER ++R +DRD
Sbjct: 1501 RKFRE------QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRD 1554
Query: 356 RERERERDRERERERDREREEEKKRHSYFEKPKV 389
R+ E +ERE + +E+ R E+ KV
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Score = 48.9 bits (115), Expect = 1e-05
Identities = 100/539 (18%), Positives = 215/539 (39%), Gaps = 93/539 (17%)
Query: 59 EMPREYNEDEDPAARRRKKKSYYAKLRQQE----IERERELAEKYRDRAKERRDGVNKDY 114
E RE E + RR +++ +L++QE +++ ++ R +ERR+ + K
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 115 EETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKV 174
EE L R + E+R QL++ + + L + + L Q++
Sbjct: 554 EEKRLEQERREQRL-------KREQEERRDQLLKREE----ERRQQRLKREQEERLEQRL 602
Query: 175 RAE----IASKEKEEEELM-EKPQKETK----KDEDPENKIEFKTRLGRNVYR--MLFKS 223
+ E + +E+ E+ L E+P++E + K E+ E + + + R + R L +
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 224 KAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPT----MEAQTTLTTNDIVI 279
+ ER E L R + E A+ + R K+ P +E++ + +
Sbjct: 663 EEEERLEQRLK-REHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYS 721
Query: 280 SKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPS----------- 328
Q RQ K+ +++ + + +E++ E D+
Sbjct: 722 RPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 329 ---TTKTPRDKERERY-RERERDRERDRDRDRERERERDRERERERDR-----EREEEKK 379
+ + P ++RER R ER + R E E+E+ R + RER++ E EE+ +
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Query: 380 RHSYFEKPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGDFF 439
R ++ + +++ + D +E +S ++ W+ E K+
Sbjct: 842 RRERAQQLQEEEDGLQED------QERRRSQEQRRDQKWRWQLEEERKRRR--------- 886
Query: 440 GMSNSYAECYPATMDDMAVD----SDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNN 495
YA+ PA + + + +EE + + ++ ++ QE+ +Y
Sbjct: 887 --HTLYAK--PALQEQLRKEQQLLQEEEEELQREEREKRR---------RQEQERQYREE 933
Query: 496 KEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGVEVKR 554
++ ++ E + R +E + E +RQ++K + +K +++ + E +R
Sbjct: 934 EQ----------LQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Score = 47.4 bits (111), Expect = 4e-05
Identities = 71/339 (20%), Positives = 146/339 (43%), Gaps = 49/339 (14%)
Query: 59 EMPREYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETE 118
E R++ EDE R +++ + + ++ +E E +L + R++ + R D K EE +
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ-QLRHDRDRKFREEEQ 1674
Query: 119 LISTTANYRAVGPTAEADKSAAEKRRQLIQ---ESKFLGGDMEHTHLVKGLDFALLQKVR 175
L+ + E D+ E+ +QL + E KFL + Q R
Sbjct: 1675 LLQEGEEQQL--RRQERDRKFREEEQQLRRQERERKFLQEEQ--------------QLRR 1718
Query: 176 AEIASKEKEEEELMEKPQKETKKDEDPENKI--EFKTRLGRNVYRMLFKSKAYERNELFL 233
E+ K +EEE+L ++ ++E + ++ KI E + R R ++ + ER+ F
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL----RRQERDRKFR 1774
Query: 234 PGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGT 293
++E + +RS+ + L + + LR
Sbjct: 1775 ----------EEEQLRQEREEQQLRSQESDRKFREEEQL--------RQEREEQQLRPQQ 1816
Query: 294 RNKKLK-KKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDR 352
R+ K + ++++ +LEE++ + + +T + R +E+E ++E E+ R ++R
Sbjct: 1817 RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876
Query: 353 DRDRERERERDRERERERDRE----REEEKKRHSYFEKP 387
+R E R +++E +R R+ + +E K H +P
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEP 1915
Score = 47.0 bits (110), Expect = 5e-05
Identities = 72/388 (18%), Positives = 160/388 (41%), Gaps = 63/388 (16%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKK--KSYYAKLRQQEIERERELAEKYRDRAKERRDGVN 111
+ R R + E+E+ R+R+ + KL+++E +R+REL E+ K R +
Sbjct: 228 QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR 287
Query: 112 KDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALL 171
++ +E E + + + + E+RR+ +E + E
Sbjct: 288 RERQEEE-----QQQQRLRREQQLRRKQEEERREQQEERREQQERREQ------------ 330
Query: 172 QKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNEL 231
Q+ R E +E+EE E+ + +++E E ++ + R ++ + + +L
Sbjct: 331 QEERRE-QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389
Query: 232 FLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQ 291
++ L E + + + Q+ Q
Sbjct: 390 RREQQLRREQQLRREQQ------------------------LRREQQLRREQQLRR--EQ 423
Query: 292 GTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERD 351
R ++ +++ + K E+++ + E+ D++ +T R ++ R ++ +RD+E +
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Query: 352 RDRDR----ERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELI 407
R R+R E E R+++ RE+ RE+E++R ++ K +E + + S ++L
Sbjct: 484 R-RERWLKLEEEERREQQERREQQLRREQEERRE---QRLKRQEEEERLQQRLRSEQQLR 539
Query: 408 KSINEKFAGSAGWEGTESLKKPEDKKQL 435
+ E+ E L K E++K+L
Sbjct: 540 REQEER---------REQLLKREEEKRL 558
Score = 46.6 bits (109), Expect = 6e-05
Identities = 75/382 (19%), Positives = 150/382 (39%), Gaps = 39/382 (10%)
Query: 21 DDPHSFHQSKLTNEDFRKLLMTPRAAPTSAPPSKSRHH---EMPREYNEDEDPAARRRKK 77
D S Q + ED R+ PR P + R E RE E E+ + ++ +
Sbjct: 104 DGKESLLQDRRQEEDQRRF--EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERL 161
Query: 78 KSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADK 137
+ + R +E+ R+R+ ++ +R E + ETE R K
Sbjct: 162 EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRK 221
Query: 138 SAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKE--------KEEEELM 189
EK++Q + + + E K +L+K ++ +E +EEE+L
Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRK--RETVLRKEEEKLQEEEPQRQRELQEEEEQLR 279
Query: 190 EKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSK---------AYERNELFLPGRMAYV 240
+ ++E +++ E + + + R + + R + + ER E R +
Sbjct: 280 KLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Query: 241 VDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKK 300
+E + +R + + E Q + + Q L +Q R ++L++
Sbjct: 340 RREQEERREQQ-----LRREQEEERREQQLRREQEE---ERREQQLRREQQLRREQQLRR 391
Query: 301 KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERER 360
+ + + E++ E + + + + +E++ RE+E +R + RE+
Sbjct: 392 EQQLRREQQLRREQQLRREQQL------RREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 361 ERDRERERERD-REREEEKKRH 381
RE+E RD +REEE +RH
Sbjct: 446 RLKREQEERRDWLKREEETERH 467
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/345 (19%), Positives = 141/345 (40%), Gaps = 61/345 (17%)
Query: 54 KSRHHEMPR---EYNEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGV 110
++ HE R + D++ R R K + R+Q+ RE++L R +ERR+
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL----RREQEERREQR 518
Query: 111 NKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFAL 170
K EE E + + + + + E+R QL++ + + L
Sbjct: 519 LKRQEEEERLQ-----QRLRSEQQLRREQEERREQLLKREE---------------EKRL 558
Query: 171 LQKVRAEIASKEKEE--EELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYER 228
Q+ R + +E+EE ++L+++ ++ ++ E + + RL R L + + E+
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618
Query: 229 NELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSY 288
R K + P E + L ++ + Q L
Sbjct: 619 -----------------------------RLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 289 LRQGTRNKKLKK-KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERD 347
+Q R ++LK+ +++ +LE++ E + E + + R++ + R + +
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEERREQ--ELAEEEQEQARERIKSRIPKWQWQ 707
Query: 348 RERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDE 392
E + D + + R R++E +R R+ +EEK+R E ++E
Sbjct: 708 LESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Score = 45.8 bits (107), Expect = 1e-04
Identities = 62/359 (17%), Positives = 147/359 (40%), Gaps = 31/359 (8%)
Query: 52 PSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQEIERE-RELAEKYRDRAKER---- 106
P K R E+ R+Y E+E+ + + R+QE ER+ RE E R + K+R
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Query: 107 --RDGVNKDYEETELISTTAN-----------YRAVGPTAEADKSAAEKRRQLIQESKFL 153
R + +E + + N +R + + D+ + + + L+ E +
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
Query: 154 GGDMEHT-------HLVKGLDFALLQKVRAEIAS-KEKEEEELMEKPQKETKKDEDPENK 205
+ E H + ++ A+ K +EE++L+ + ++E ++ ++ + K
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRK 1337
Query: 206 IEFKTRL----GRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKA 261
+ +L R + + + EL + ++ + + ++ +
Sbjct: 1338 FREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397
Query: 262 DCPTMEAQTTLTTN-DIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFE 320
E + L + D + Q LS + + ++ +++ + + E+K E + + +
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 321 DIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKK 379
+ + +++E ++ +ERDR+ + + R +ERDR+ + R +E E+K
Sbjct: 1458 ERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Score = 45.4 bits (106), Expect = 1e-04
Identities = 94/540 (17%), Positives = 217/540 (40%), Gaps = 47/540 (8%)
Query: 49 SAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYA---KLRQQEIERERELAEKYRDRAKE 105
S + R ++ RE E + +R +++ K +E RE+ELAE+ +++A+E
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Query: 106 R-RDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQE------SKFLGGDME 158
R + + K + E + A+ R + K ++RRQ +E S+ + E
Sbjct: 696 RIKSRIPKWQWQLE---SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Query: 159 HTHLVKG-----LDFALL-----------QKVRAEIASKEKEEEELM--EKPQKETKKDE 200
H + DF Q++ A +E+ E +L E+ Q+E +
Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812
Query: 201 DPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSK 260
+ E K + + + + F E +L R + + +D + +
Sbjct: 813 EEEEKEQRRRQRREREKELQFLE---EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869
Query: 261 ADCP---TMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMN 317
D +E + + + Q Q ++ ++ + + E+++ E +
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Query: 318 IFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEE 377
E+ + + + +ERE+ R +ER+R+ +D+ +++ E+ E E+ R +E E
Sbjct: 930 YREE--EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Query: 378 KKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQLGD 437
KK E + +++ + ++ +E + +K E + L++ +K++L +
Sbjct: 988 KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK--DELQQEEEQLLREEREKRRLQE 1045
Query: 438 FFGMSNSYAECYPATMDDMAVDSDEEVDYSKMD---QGNKKGPLGRWDFDTQEEYSEYMN 494
Y E ++ + +E + + Q K+ L + + E E
Sbjct: 1046 ---RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 495 NKEALPKAAFQYGIKMSEGRKTRRFKETNDKAELDRQWKKISAIIEKRKKMEADGVEVKR 554
+E + + ++ E + R +E + EL+RQ+++ + ++ +++ + E +R
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162
Score = 44.7 bits (104), Expect = 2e-04
Identities = 65/364 (17%), Positives = 147/364 (40%), Gaps = 50/364 (13%)
Query: 54 KSRHHEMPREYNEDED------------PAARRRKKKSYYAKLRQQEIERERELAEKYRD 101
K R E+ R+Y E+E+ P RRR++ + ++ + E +L + ++
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQE 1189
Query: 102 RAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTH 161
+ ++ R+ ++ EE + YR ++ ++ ++++K E+
Sbjct: 1190 KRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQ 1249
Query: 162 LVKGLDFAL--------LQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLG 213
+ D L LQ + E +++E+E + + +E+ + E K
Sbjct: 1250 FRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 214 RNVYRMLFKSKAYERNELFLPGR--MAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTT 271
R+ K+ E +L R + D ++ + + L++ + + P +
Sbjct: 1310 RD-------RKSQEEKQLLREEREEKRRRQETDRKFREEE---QLLQEREEQPLRRQERD 1359
Query: 272 LTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEK--KPPEADMNIFEDIGDYVPST 329
+ + Q +L + R ++ +++ K EE+ + E + + +D
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQD-------- 1411
Query: 330 TKTPRDKERERYRERERDRER-DRDRDRERERERDRERERERDREREEEKKRHSYFEKPK 388
RD+ ++RE E+ R +RDR E ++ R +ERER EE++ R K +
Sbjct: 1412 ----RDR---KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 389 VDDE 392
+++
Sbjct: 1465 EEEQ 1468
Score = 42.7 bits (99), Expect = 9e-04
Identities = 74/385 (19%), Positives = 155/385 (40%), Gaps = 67/385 (17%)
Query: 56 RHHEMPREYNEDEDPAARRRKKKSYYAK---LRQQEIE------RERELAEKYRDRAKER 106
RH E R++ E+E R+ +++ + + LR QE E R+R+ E+ + +++
Sbjct: 1368 RHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQE 1427
Query: 107 RDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGL 166
RD K EE + + R E ++ ++R + +E + L + E L
Sbjct: 1428 RD--RKFREEEQQVRRQERERKF---LEEEQQLRQERHRKFREEEQLLQEREEQQLH--- 1479
Query: 167 DFALLQKVRAEIASKEKEEEELMEKPQKETK------KDEDPENK-IEFKTRLGRNVYRM 219
R E K EEE+ + + +++ K + ++PE K +E + +L R +
Sbjct: 1480 --------RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Query: 220 LF--KSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDI 277
F + + R E R D D ++ + + R + E +
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQ----DRDRKFREEE-QLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 278 VISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRD-- 335
+ + Q ++ + ++ + + + + E + D + ++ + + R
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 336 KERERYRERERDRERDRDRDRE----------------RERERDRE----------RERE 369
+E + R +ER+++ DRDR+ R +ERDR+ +ERE
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706
Query: 370 RDREREEEKKRHSYFEKPKVDDEPM 394
R +EE++ R E+ ++E +
Sbjct: 1707 RKFLQEEQQLRRQELERKFREEEQL 1731
Score = 40.0 bits (92), Expect = 0.006
Identities = 73/320 (22%), Positives = 131/320 (40%), Gaps = 43/320 (13%)
Query: 67 DEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANY 126
DE+ AR K+S RQ+E +R E ++ + +R + +E EL
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL------- 148
Query: 127 RAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKEK--- 183
AE ++ + EK+ +L Q + + L + R E +E+
Sbjct: 149 ------AEGEEQS-EKQERLEQRDRQRRDEE-------------LWRQRQEWQEREERRA 188
Query: 184 EEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDL 243
EEE+L ET++ D E + + R + R + K +R E R V
Sbjct: 189 EEEQLQSCKGHETEEFPDEE---QLRRRELLELRRKGREEKQQQRRE-----RQDRVFQE 240
Query: 244 DDEYADTDIPTTLIRSKADCPTMEAQTT--LTTNDIVISKLT-QILSYLRQGTRNKKLKK 300
++E T L + + E Q L + + KL Q L RQ ++ +
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300
Query: 301 KDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDRDRDRERER 360
+ + +L K+ E E+ + + +E++ RE+E RE+ R++E ER
Sbjct: 301 RREQQLRRKQEEERREQQ-EERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 361 ERDRERERERDREREEEKKR 380
R+++ RE++ ER E++ R
Sbjct: 360 -REQQLRREQEEERREQQLR 378
Score = 35.0 bits (79), Expect = 0.18
Identities = 64/354 (18%), Positives = 147/354 (41%), Gaps = 31/354 (8%)
Query: 54 KSRHHEMPREYNEDEDPAARRRKKKSYYA--KLRQQEIER---ERELAEKYRDRAKERRD 108
K R E R+ E++ + + R +K K+R+QE ER E E + ++ ++ R
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615
Query: 109 GVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLIQESKFLGGDMEHTHLVKGLDF 168
++ + E E + + + E D+ E+ QL ++ + + H K +
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLH-RQERDRKFLEEEPQLRRQER--EQQLRHDRDRKFREE 1672
Query: 169 ALLQKVRAEIASKEKEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYER 228
L + E + +E + + +++ ++ E ++ + +L R F+ + R
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 229 NELF---LPGRMAYVVDLDDEYADTDIPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQI 285
E L + Y L++E + +R + + L + +
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQL--------RQERE 1784
Query: 286 LSYLRQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERE 345
LR ++K +++++ + E + E + + G Y + +++ +R R+ E
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQERE---EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ-E 1840
Query: 346 RDRE-------RDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDE 392
RDR+ +++ R E+E +E E++R +ER E K R + + + +++
Sbjct: 1841 RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER-ERKLREEHIRRQQKEEQ 1893
Score = 33.9 bits (76), Expect = 0.40
Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 16/132 (12%)
Query: 277 IVISKLTQILSY-LRQGT---RNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYV---PST 329
+ I K+ Q Y L Q T K+ + K L + + E D FE + P
Sbjct: 76 LFIFKVAQACYYALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQ 135
Query: 330 TKTPRDKERERY--------RERERDRERDRDR-DRERERERDRERERERDREREEEKKR 380
+ + +E+ER ++ER +RDR R D E R+R +ERE R EE+ +
Sbjct: 136 RRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQS 195
Query: 381 HSYFEKPKVDDE 392
E + DE
Sbjct: 196 CKGHETEEFPDE 207
Score = 30.8 bits (68), Expect = 3.4
Identities = 19/73 (26%), Positives = 42/73 (57%), Gaps = 8/73 (10%)
Query: 334 RDKERERYRER-------ERDRE-RDRDRDRERERERDRERERERDREREEEKKRHSYFE 385
R++++++ RER E ++E R R+ +E E+ +E E +R RE +EE+++ E
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 386 KPKVDDEPMDVDK 398
+ ++ E + ++
Sbjct: 283 RQELRRERQEEEQ 295
Score = 29.3 bits (64), Expect = 9.9
Identities = 14/56 (25%), Positives = 30/56 (53%)
Query: 331 KTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEK 386
+T + E+ R RE R + R+ ++++ R+R+ ++ E +E +KR + K
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 61.6 bits (148), Expect = 2e-09
Identities = 33/73 (45%), Positives = 45/73 (61%), Gaps = 1/73 (1%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVD-DE 392
RD++RER +E ER R RDRD D+ER ER++ERER R+R +E+ + +K K D D+
Sbjct: 350 RDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD 409
Query: 393 PMDVDKGPGSTKE 405
D S KE
Sbjct: 410 RRHRDDKRDSKKE 422
Score = 55.8 bits (133), Expect = 1e-07
Identities = 28/71 (39%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query: 328 STTKTPRDKERERYRERERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKP 387
S ++ + R+R RERE++ ER R RDR+ ++ER ERE+ER+R RE K++ S +
Sbjct: 340 SRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRS---RG 396
Query: 388 KVDDEPMDVDK 398
+V+++ DK
Sbjct: 397 EVEEKKHKEDK 407
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/159 (24%), Positives = 70/159 (44%), Gaps = 23/159 (14%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEA---DMNIFEDIGDYVPSTTKTPRDKERERYRER-- 344
R +R++K ++D+ + EK+ D + ++ G+ R+KERER RER
Sbjct: 339 RSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGN--------EREKERERSRERSK 390
Query: 345 ---------ERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMD 395
E+ + D+D R R+ +RD ++E++ R R E+K S
Sbjct: 391 EQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRS 450
Query: 396 VDKGPGST-KELIKSINEKFAGSAGWEGTESLKKPEDKK 433
K S K K + K + S T+S++K + ++
Sbjct: 451 RSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/89 (33%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 293 TRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPR-DKERERYRERERDRERD 351
TR +K+KK K EE D ++ E P + +PR R R R R+
Sbjct: 235 TRPRKIKKDGKEGAEE-----IDRHV-ERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGS 288
Query: 352 RDRDRERERERDRERERERDREREEEKKR 380
DRE ERE++R+R +ERE+E++R
Sbjct: 289 SSFDRELEREKERQRLEREAKEREKERRR 317
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 3/94 (3%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRE 349
R +R+K+ K K + +EK + + D V + K +E+ R+R R +E
Sbjct: 447 RSRSRSKEKSSKHKNESKEKSNKRSRSGS-QGRTDSVEKSKKREHSPSKEKSRKRSRSKE 505
Query: 350 RDRDRDRERERERDRERERERDR--EREEEKKRH 381
R RD +++ + +R R + E+E ++K+H
Sbjct: 506 RSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539
Score = 38.5 bits (88), Expect = 0.016
Identities = 21/93 (22%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 290 RQGTRNKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTP-RDKERERYRERERDR 348
R ++ K K K++ K + K + D + +P ++K R+R R +ER
Sbjct: 449 RSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSH 508
Query: 349 ERDRDRDRERERERDRERERERDREREEEKKRH 381
+RD +++ + DR R + ++E +E++ ++
Sbjct: 509 KRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKN 541
Score = 34.7 bits (78), Expect = 0.24
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 10/104 (9%)
Query: 295 NKKLKKKDKGKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRERERDRERDR-- 352
+KK KK + + E+K + + G S +K K + +E+ R R
Sbjct: 419 SKKEKKHSRSRSRERKHRSRSRS--RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQ 476
Query: 353 ------DRDRERERERDRERERERDREREEEKKRHSYFEKPKVD 390
++ ++RE +E+ R+R R +E KR K + D
Sbjct: 477 GRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSD 520
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 60.1 bits (144), Expect = 5e-09
Identities = 99/517 (19%), Positives = 200/517 (38%), Gaps = 45/517 (8%)
Query: 65 NEDEDPAARRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTA 124
++DE+ AAR R++++ +LRQ++ E E + D+ + D EE + +T
Sbjct: 31 DDDEEEAARERRRRARQERLRQKQ---EEESLGQVTDQVEVNAQNSVPD-EEAKTTTTNT 86
Query: 125 NYRAVGPTAEADKSAA--EKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIASKE 182
A ++ A E+R++ +QE+ + + T L + ++
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 183 KEEEELMEKPQKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLP-----GRM 237
E+EE E Q+ + +E ++ R+ + K E E P G
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 238 AYVVDLDDEYADTDIPTTLIRSK-----ADCPTMEAQTTLTTNDIVISKLTQILSYLRQG 292
V ++++ ++ T ++ K ++ P E + +++I + + R
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266
Query: 293 TRNKKLKKKDKGKLEEKKPPE-ADMNIFEDIGDYVPSTTKTPRD-KERERYRERERDRER 350
+L+ +++ +++ ++ + AD + + + + R+ +ERER RE E+
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Query: 351 DRDRDRERERERDRERER----------ERDREREEEKKRHSYFEKPKVDDEPMDVDKGP 400
+R R +E E+ ER+R ER R +EEEK+ ++ + ++E +
Sbjct: 327 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Query: 401 GSTKEL---------IKSINEKFAGSAGWEGTESLKKPEDKKQLGDFFGMSNSYAECYPA 451
K+L K EK + K EDK Q A
Sbjct: 387 KRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQA 446
Query: 452 TMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYGIKMS 511
+ + D D+ KK D + +EE +M+ K+ + Q G M+
Sbjct: 447 KREKLQEDKPTFKKEEIKDEKIKK------DKEPKEEVKSFMDRKKGFTEVKSQNGEFMT 500
Query: 512 EGRK--TRRFKETNDKAELDRQWKKISAIIEKRKKME 546
K F +A +D + + + +E K++E
Sbjct: 501 HKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLE 537
Score = 51.2 bits (121), Expect = 2e-06
Identities = 87/417 (20%), Positives = 164/417 (39%), Gaps = 55/417 (13%)
Query: 28 QSKLTNEDFRKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYYAKLRQQ 87
Q K ++ ++ +AA ++ E RE + +R K++ A +Q
Sbjct: 284 QDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQ 343
Query: 88 EIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKRRQLI 147
I+ E + A + R R KE + EE + +A + +K EK+ +
Sbjct: 344 RIKEEEKRAAEERQRIKEEE---KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAM- 399
Query: 148 QESKFLGGDMEHTHLVKG------------LDFALLQKVRAEIASKEKEEEELMEKPQKE 195
QE+K G +E ++G L A+L+K E +K + + E +++ +
Sbjct: 400 QETKIKGEKVEQK--IEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPT 457
Query: 196 TKKDEDPENKIEFKTRLGRNVYRMLFKSKAY----ERNELFLPGRMAYVVDLDDEYADTD 251
KK+E + KI+ V + + K + +N F+ ++ + T+
Sbjct: 458 FKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKH----------TE 507
Query: 252 IPTTLIRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKP 311
+ +A T EA+ + K + L R T +++ +K ++K
Sbjct: 508 NTFSRPGGRASVDTKEAEGA---PQVEAGKRLEELRRRRGETESEEFEKL------KQKQ 558
Query: 312 PEADMNIFEDIGDYVPSTTKTPRDKERERYRERE-RDRERDRDRDRERERERDRERERER 370
EA + + E K R++ R+ E E R ++ + DR E E+ R +E
Sbjct: 559 QEAALELEE---------LKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIE 609
Query: 371 DREREEEKKRHSYFEKPKVDD-EPMDVDKGPGST---KELIKSINEKFAGSAGWEGT 423
R E +KR E DD +P GS+ +E + +N+ S+G + T
Sbjct: 610 RRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKST 666
Score = 33.1 bits (74), Expect = 0.69
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 334 RDKERERYRERERDR-ERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDE 392
R K E E ER +R+ D + E RER R +ER R+++EE+ ++ +V+ +
Sbjct: 12 RQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQ 71
Query: 393 PMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKKQ 434
D+ +T + N + G E L + E+++Q
Sbjct: 72 NSVPDEEAKTT-----TTNTQVEGDDEAAFLERLARREERRQ 108
Score = 32.7 bits (73), Expect = 0.90
Identities = 30/128 (23%), Positives = 51/128 (39%), Gaps = 9/128 (7%)
Query: 27 HQSKLTNEDF-----RKLLMTPRAAPTSAPPSKSRHHEMPREYNEDEDPAARRRKKKSYY 81
H+ K T F R + T A + R E+ R E E + K+K
Sbjct: 501 HKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQE 560
Query: 82 AKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAE 141
A L +E++++RE K + ++RR K E + R + E ++ A
Sbjct: 561 AALELEELKKKREERRKVLEEEEQRR----KQEEADRKLREEEEKRRLKEEIERRRAEAA 616
Query: 142 KRRQLIQE 149
++RQ + E
Sbjct: 617 EKRQKMPE 624
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 60.1 bits (144), Expect = 5e-09
Identities = 30/67 (44%), Positives = 38/67 (56%), Gaps = 5/67 (7%)
Query: 334 RDKERERYRERERDRERDRDRDRERERERD-----RERERERDREREEEKKRHSYFEKPK 388
RD+ +++ R R RDR RDRDRDRER R+RD R R R R R RE K + Y + +
Sbjct: 168 RDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSR 227
Query: 389 VDDEPMD 395
P D
Sbjct: 228 SQSPPKD 234
Score = 54.7 bits (130), Expect = 2e-07
Identities = 46/192 (23%), Positives = 83/192 (43%), Gaps = 30/192 (15%)
Query: 276 DIVISKLTQILSYLRQGTRNKKLK------KKDKGKLEEKKP--------------PEAD 315
D +IS L +++ +R + K K +K KL+E P E D
Sbjct: 79 DSLISNLLRLIQTMRPPAKPSTSKDPVVKPKTEKEKLKELFPVLCQPDNPSVRTMLDEDD 138
Query: 316 MNIFEDIGDYVPSTTKTPRDKERER---YRERERDRERDRDRDRERERERDRERERERD- 371
+ + D+ + + + +E++R +R+R + ++R R RDR R+R+RDRER R+RD
Sbjct: 139 VKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDH 198
Query: 372 --REREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKELIKSINEKFA--GSAGWEGTESLK 427
R R + R E+ KV + K+ + +K+ W +
Sbjct: 199 KRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKD--RKDRDKYGERNLDRWRDKHVDR 256
Query: 428 KPEDKKQLGDFF 439
P ++ +GD +
Sbjct: 257 PPPEEPTIGDIY 268
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 59.7 bits (143), Expect = 7e-09
Identities = 103/487 (21%), Positives = 197/487 (40%), Gaps = 53/487 (10%)
Query: 89 IERERELAEKYRD----RAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKR- 143
I+ E+EL E+ + +AK+R+ NKD + + + A +A A A K+
Sbjct: 586 IKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQF 645
Query: 144 RQLIQE---SKFLGGDMEHTHLVKGLDFALLQ-KVRAEIAS---KEKEEEELMEKPQKET 196
+ ++ E S F + E +V + LL K R ++ K + EEE EK K
Sbjct: 646 KDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIM 705
Query: 197 KKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTL 256
+ ED + +E R + A + R + + D A +
Sbjct: 706 QAKEDFKKMMEEAKFNPRATFSEFAAKHAKD-------SRFKAIEKMKDREALFNEFVAA 758
Query: 257 IRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADM 316
R K E + + T + + S ++LS ++++ K KDK + + +
Sbjct: 759 ARKK------EKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSS 812
Query: 317 NIFEDI-GDYVPSTTKTPRDKERERYRERERDRERD-RDRDRERERERDRERERERDRER 374
++ ED+ Y+ K D E+E+ ER+ E R+R+RE ++ R E+ +E DRER
Sbjct: 813 SMREDLFKQYIEKIAKN-LDSEKEKELERQARIEASLREREREVQKARS-EQTKEIDRER 870
Query: 375 EEEKKRHSYFE-KPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKK 433
E+ K+ + K + D D T+ ++ + WE L++ E +K
Sbjct: 871 EQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHR-------WESGSLLEREEKEK 923
Query: 434 QLGDFF-GMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGP----LGRWDFDTQEE 488
+ ++ E + +D+ + + + ++ + K+ P D Q E
Sbjct: 924 LFNEHIEALTKKKREHFRQLLDETSAITLTST-WKEVKKIIKEDPRCIKFSSSDRKKQRE 982
Query: 489 YSEYMNNKEALPKAAFQ----------YGIKMSEGRKTRRFKETNDKAELDRQWKKISAI 538
+ EY+ +K KA F+ Y K + K+ + D+++ + +
Sbjct: 983 FEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCV 1042
Query: 539 IEKRKKM 545
E+R+K+
Sbjct: 1043 PEERRKL 1049
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 59.7 bits (143), Expect = 7e-09
Identities = 103/487 (21%), Positives = 197/487 (40%), Gaps = 53/487 (10%)
Query: 89 IERERELAEKYRD----RAKERRDGVNKDYEETELISTTANYRAVGPTAEADKSAAEKR- 143
I+ E+EL E+ + +AK+R+ NKD + + + A +A A A K+
Sbjct: 607 IKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQF 666
Query: 144 RQLIQE---SKFLGGDMEHTHLVKGLDFALLQ-KVRAEIAS---KEKEEEELMEKPQKET 196
+ ++ E S F + E +V + LL K R ++ K + EEE EK K
Sbjct: 667 KDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIM 726
Query: 197 KKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNELFLPGRMAYVVDLDDEYADTDIPTTL 256
+ ED + +E R + A + R + + D A +
Sbjct: 727 QAKEDFKKMMEEAKFNPRATFSEFAAKHAKD-------SRFKAIEKMKDREALFNEFVAA 779
Query: 257 IRSKADCPTMEAQTTLTTNDIVISKLTQILSYLRQGTRNKKLKKKDKGKLEEKKPPEADM 316
R K E + + T + + S ++LS ++++ K KDK + + +
Sbjct: 780 ARKK------EKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSS 833
Query: 317 NIFEDI-GDYVPSTTKTPRDKERERYRERERDRERD-RDRDRERERERDRERERERDRER 374
++ ED+ Y+ K D E+E+ ER+ E R+R+RE ++ R E+ +E DRER
Sbjct: 834 SMREDLFKQYIEKIAKN-LDSEKEKELERQARIEASLREREREVQKARS-EQTKEIDRER 891
Query: 375 EEEKKRHSYFE-KPKVDDEPMDVDKGPGSTKELIKSINEKFAGSAGWEGTESLKKPEDKK 433
E+ K+ + K + D D T+ ++ + WE L++ E +K
Sbjct: 892 EQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHR-------WESGSLLEREEKEK 944
Query: 434 QLGDFF-GMSNSYAECYPATMDDMAVDSDEEVDYSKMDQGNKKGP----LGRWDFDTQEE 488
+ ++ E + +D+ + + + ++ + K+ P D Q E
Sbjct: 945 LFNEHIEALTKKKREHFRQLLDETSAITLTST-WKEVKKIIKEDPRCIKFSSSDRKKQRE 1003
Query: 489 YSEYMNNKEALPKAAFQ----------YGIKMSEGRKTRRFKETNDKAELDRQWKKISAI 538
+ EY+ +K KA F+ Y K + K+ + D+++ + +
Sbjct: 1004 FEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCV 1063
Query: 539 IEKRKKM 545
E+R+K+
Sbjct: 1064 PEERRKL 1070
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 58.9 bits (141), Expect = 1e-08
Identities = 74/282 (26%), Positives = 119/282 (42%), Gaps = 34/282 (12%)
Query: 291 QGTRNKKLKKKDK--GKLEEKKPPEADMNIFEDIGDYVPSTTKTPRDKERERYRE----- 343
Q KK KK+D G +++ + + + + ST +T ++ + RE
Sbjct: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
Query: 344 ----------RERDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEP 393
++R RE R+ R RE ER R+RE ER + +EEEK++ EK K D
Sbjct: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRI 256
Query: 394 MDVDKGPGSTK-----ELIKSINEKFAGSAGWEGTE-SLKKPEDKKQLGDFFGMSNSYAE 447
+ DK K L++++N+K +G E L K E K+L D +S+ A
Sbjct: 257 PERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKL-DKENLSDERAS 315
Query: 448 CYPATMDDMAVDSDEEVDYSKMDQGNKKGPLGRWDFDTQEEYSEYMNNKEALPKAAFQYG 507
T+ SD E+ K K P D +E EY ++E + + +
Sbjct: 316 GQSCTLPKR---SDSELKDEK-----PKRPEDESGRDYREREREYERDQERILRERERLK 367
Query: 508 IKMSEGR--KTRRFKETNDKAELDRQWKKISAIIEKRKKMEA 547
+ E R K R KE K + + K+ + +K KK E+
Sbjct: 368 RQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAES 409
Score = 49.7 bits (117), Expect = 7e-06
Identities = 39/150 (26%), Positives = 70/150 (46%), Gaps = 29/150 (19%)
Query: 294 RNKKLKKKDKGKLEEKK--------PPEADMNIFEDIGDYVPSTTKTPRDKERERYRERE 345
+ +K KK DK L +++ P +D + ++ K P D+ YRERE
Sbjct: 297 KREKAKKLDKENLSDERASGQSCTLPKRSDSELKDE-------KPKRPEDESGRDYRERE 349
Query: 346 RDRERDRDRDRERERERDRERERERDREREEEKKRHSYFEKPKVDDEPMDVDKGPGSTKE 405
R+ ERD++R R+RER + ++ ER +K+R+ + K +E M +K
Sbjct: 350 REYERDQERIL-----RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEK------- 397
Query: 406 LIKSINEKFAGSAGWEGTESLKKPEDKKQL 435
++ +K + E S +K E K+++
Sbjct: 398 --DTLRDKGKKAESTESIGSSEKTEKKEEV 425
Score = 29.3 bits (64), Expect = 9.9
Identities = 40/181 (22%), Positives = 73/181 (40%), Gaps = 22/181 (12%)
Query: 73 RRRKKKSYYAKLRQQEIERERELAEKYRDRAKERRDGVNKDYEETELISTTANYRAV--G 130
++R ++ + R++EIER+R+ E+ R + KE KD E+ + I +
Sbjct: 207 KQRMREEKREERRRREIERKRQ-REEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDE 265
Query: 131 PTAEADK---SAAEKRRQLIQESKFLGGDMEHTHLVKGLDFALLQKVRAEIAS----KEK 183
P + + A ++ L + K +++ K LD L RA S K
Sbjct: 266 PKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRS 325
Query: 184 EEEELMEKP------------QKETKKDEDPENKIEFKTRLGRNVYRMLFKSKAYERNEL 231
+ E EKP ++E + + D E + + RL R + + YE+ +
Sbjct: 326 DSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKT 385
Query: 232 F 232
F
Sbjct: 386 F 386
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,622,883
Number of Sequences: 37866
Number of extensions: 1139550
Number of successful extensions: 27092
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 494
Number of HSP's successfully gapped in prelim test: 561
Number of HSP's that attempted gapping in prelim test: 8113
Number of HSP's gapped (non-prelim): 7881
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.