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Search of human proteins with 125987596
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
sapiens]
(1137 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa... 2305 0.0
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap... 2263 0.0
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans... 1303 0.0
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo... 1296 0.0
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans... 1295 0.0
gi|155722998 solute carrier family 4, sodium bicarbonate transpo... 974 0.0
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp... 966 0.0
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp... 964 0.0
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans... 842 0.0
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans... 821 0.0
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 598 e-170
gi|157671953 solute carrier family 4, anion exchanger, member 3 ... 598 e-170
gi|156071474 solute carrier family 4, anion exchanger, member 2 ... 593 e-169
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H... 525 e-148
gi|14042960 solute carrier family 4 member 11 [Homo sapiens] 212 2e-54
gi|55956899 keratin 9 [Homo sapiens] 60 1e-08
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s... 59 3e-08
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 57 8e-08
gi|33620755 YEATS domain containing 2 [Homo sapiens] 57 1e-07
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 57 1e-07
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 57 1e-07
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 57 1e-07
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 56 2e-07
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] 55 3e-07
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 55 3e-07
gi|109452587 family with sequence similarity 98, member B isofor... 55 3e-07
gi|195972866 keratin 10 [Homo sapiens] 55 4e-07
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 54 6e-07
gi|12056465 fibrillarin [Homo sapiens] 54 8e-07
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol... 53 2e-06
>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
sapiens]
Length = 1137
Score = 2305 bits (5973), Expect = 0.0
Identities = 1137/1137 (100%), Positives = 1137/1137 (100%)
Query: 1 MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60
MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG
Sbjct: 1 MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60
Query: 61 LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120
LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL
Sbjct: 61 LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120
Query: 121 QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180
QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS
Sbjct: 121 QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180
Query: 181 GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240
GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR
Sbjct: 181 GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240
Query: 241 SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300
SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK
Sbjct: 241 SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300
Query: 301 DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360
DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI
Sbjct: 301 DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360
Query: 361 GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420
GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA
Sbjct: 361 GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420
Query: 421 DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA
Sbjct: 421 DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
Query: 481 MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540
MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG
Sbjct: 481 MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540
Query: 541 GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600
GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL
Sbjct: 541 GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600
Query: 601 DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660
DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF
Sbjct: 601 DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660
Query: 661 KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720
KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL
Sbjct: 661 KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720
Query: 721 SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780
SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD
Sbjct: 721 SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780
Query: 781 FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840
FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL
Sbjct: 781 FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840
Query: 841 LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900
LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI
Sbjct: 841 LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900
Query: 901 AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960
AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF
Sbjct: 901 AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960
Query: 961 LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1020
LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF
Sbjct: 961 LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1020
Query: 1021 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1080
TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE
Sbjct: 1021 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1080
Query: 1081 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1137
TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL
Sbjct: 1081 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1137
>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
Length = 1121
Score = 2263 bits (5863), Expect = 0.0
Identities = 1121/1137 (98%), Positives = 1121/1137 (98%), Gaps = 16/1137 (1%)
Query: 1 MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60
MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG
Sbjct: 1 MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60
Query: 61 LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120
LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL
Sbjct: 61 LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120
Query: 121 QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180
QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS
Sbjct: 121 QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180
Query: 181 GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240
GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR
Sbjct: 181 GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240
Query: 241 SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300
SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK
Sbjct: 241 SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300
Query: 301 DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360
DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI
Sbjct: 301 DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360
Query: 361 GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420
GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA
Sbjct: 361 GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420
Query: 421 DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA
Sbjct: 421 DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
Query: 481 MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540
MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG
Sbjct: 481 MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540
Query: 541 GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600
GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL
Sbjct: 541 GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600
Query: 601 DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660
DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF
Sbjct: 601 DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660
Query: 661 KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720
KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL
Sbjct: 661 KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720
Query: 721 SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780
SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD
Sbjct: 721 SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780
Query: 781 FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840
FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL
Sbjct: 781 FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840
Query: 841 LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900
LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI
Sbjct: 841 LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900
Query: 901 AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960
AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF
Sbjct: 901 AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960
Query: 961 LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1020
LYMGVASLNGIQ FWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF
Sbjct: 961 LYMGVASLNGIQ----------------FWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1004
Query: 1021 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1080
TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE
Sbjct: 1005 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1064
Query: 1081 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1137
TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL
Sbjct: 1065 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1121
>gi|148596928 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 1 [Homo sapiens]
Length = 1079
Score = 1303 bits (3371), Expect = 0.0
Identities = 671/1101 (60%), Positives = 825/1101 (74%), Gaps = 86/1101 (7%)
Query: 31 IHIGLPVPTYPQRKTDQK---GHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLI 87
I+IG+ VP +R+ K GH +K ++ + + ++ +SS ++
Sbjct: 29 IYIGVHVPKSYRRRRRHKRKTGHKEKKEK-------ERISENYSDKSDIENADESSSSIL 81
Query: 88 SRTRSPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEG 145
SPAAE+++ ILGEED++P P LFTE+D L DG +MEWKE+ARWIKFEEKVE+G
Sbjct: 82 KPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQG 141
Query: 146 GERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELR 205
GERWSKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+
Sbjct: 142 GERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELK 201
Query: 206 ERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSA 265
++V+Y LLR+HRHQTKK RSLADIGK+VS+ +R P++ H
Sbjct: 202 DKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR---------- 251
Query: 266 NYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRL 325
+ S S+NDIS P DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL
Sbjct: 252 ------NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRL 305
Query: 326 IQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNRED 385
Q+ MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R D
Sbjct: 306 QQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHD 365
Query: 386 LIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGA 445
LIAGIDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S E QMNG GG
Sbjct: 366 LIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH 425
Query: 446 PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRK 505
GGG+G EEL TGRF GGL DIKRK
Sbjct: 426 GGGGHGDC--------------------------------EELQRTGRFCGGLIKDIKRK 453
Query: 506 LPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGS 565
P+F SDFYD +IQ++SAILFIYL +TNAITFGGLLGDATDN QGV+ESFLGTA++G+
Sbjct: 454 APFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGA 513
Query: 566 LFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDA 625
+FCLF+GQPL ILSSTGP+L+FE+LLF+FSK N DY+EFRLWIGL SA CLILVATDA
Sbjct: 514 IFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDA 573
Query: 626 SFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPD 685
SF+++Y TRFTEEGFS+LISFIFIYDA KKMI YYPIN +FK + T + C CV PD
Sbjct: 574 SFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPD 633
Query: 686 TVNTTVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDL 743
N ++ N + LAP+ S ++ + T DW+ LSKKEC YGG L+GN+C F+PD+
Sbjct: 634 PANISISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692
Query: 744 ALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPK 803
LMSFILF GTY+ ++ LKKFK S YFPT R L++DF+I+ SIL+FC IDA G++TPK
Sbjct: 693 TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPK 752
Query: 804 LHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENK 863
L VPS KPT P+RGWFV PFG+NPWWV A+ +PALLVTILIFMDQQITAVIVNRKE+K
Sbjct: 753 LIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHK 812
Query: 864 LKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLG 923
LKK AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLG
Sbjct: 813 LKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLG 872
Query: 924 VREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQ 983
VREQRVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q
Sbjct: 873 VREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ----------- 921
Query: 984 KKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIF 1043
F +R KL LMP KHQPD +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIF
Sbjct: 922 -----FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIF 976
Query: 1044 PVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQF 1101
PVMIL L+ VR+ +D++FSQHDL+++D+++PEK+ KKE +KK+K+KKG+ + +++
Sbjct: 977 PVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDC 1036
Query: 1102 P----PPSVIKIPMESVQSDP 1118
P PS IKIPM+ ++ P
Sbjct: 1037 PYSEKVPS-IKIPMDIMEQQP 1056
>gi|4507025 solute carrier family 4, sodium bicarbonate cotransporter,
member 4 isoform 2 [Homo sapiens]
Length = 1035
Score = 1296 bits (3354), Expect = 0.0
Identities = 659/1037 (63%), Positives = 799/1037 (77%), Gaps = 76/1037 (7%)
Query: 92 SPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEGGERW 149
SPAAE+++ ILGEED++P P LFTE+D L DG +MEWKE+ARWIKFEEKVE+GGERW
Sbjct: 42 SPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERW 101
Query: 150 SKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVS 209
SKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+++V+
Sbjct: 102 SKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVT 161
Query: 210 YVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGR 269
Y LLR+HRHQTKK RSLADIGK+VS+ +R P++ H
Sbjct: 162 YTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR-------------- 207
Query: 270 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329
+ S S+NDIS P DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL Q+
Sbjct: 208 --NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAV 265
Query: 330 MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389
MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R DLIAG
Sbjct: 266 MLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAG 325
Query: 390 IDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGG 449
IDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S E QMNG GG GGG
Sbjct: 326 IDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGG 385
Query: 450 NGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWF 509
+G EEL TGRF GGL DIKRK P+F
Sbjct: 386 HGDC--------------------------------EELQRTGRFCGGLIKDIKRKAPFF 413
Query: 510 PSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCL 569
SDFYD +IQ++SAILFIYL +TNAITFGGLLGDATDN QGV+ESFLGTA++G++FCL
Sbjct: 414 ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 473
Query: 570 FSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFII 629
F+GQPL ILSSTGP+L+FE+LLF+FSK N DY+EFRLWIGL SA CLILVATDASF++
Sbjct: 474 FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 533
Query: 630 KYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNT 689
+Y TRFTEEGFS+LISFIFIYDA KKMI YYPIN +FK + T + C CV PD N
Sbjct: 534 QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 593
Query: 690 TVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMS 747
++ N + LAP+ S ++ + T DW+ LSKKEC YGG L+GN+C F+PD+ LMS
Sbjct: 594 SISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMS 652
Query: 748 FILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVP 807
FILF GTY+ ++ LKKFK S YFPT R L++DF+I+ SIL+FC IDA G++TPKL VP
Sbjct: 653 FILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVP 712
Query: 808 SVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKA 867
S KPT P+RGWFV PFG+NPWWV A+ +PALLVTILIFMDQQITAVIVNRKE+KLKK
Sbjct: 713 SEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKG 772
Query: 868 AGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQ 927
AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLGVREQ
Sbjct: 773 AGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQ 832
Query: 928 RVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLT 987
RVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q
Sbjct: 833 RVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ--------------- 877
Query: 988 PFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMI 1047
F +R KL LMP KHQPD +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIFPVMI
Sbjct: 878 -FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMI 936
Query: 1048 LGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQFP--- 1102
L L+ VR+ +D++FSQHDL+++D+++PEK+ KKE +KK+K+KKG+ + +++ P
Sbjct: 937 LALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSE 996
Query: 1103 -PPSVIKIPMESVQSDP 1118
PS IKIPM+ ++ P
Sbjct: 997 KVPS-IKIPMDIMEQQP 1012
>gi|197927160 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 3 [Homo sapiens]
Length = 1094
Score = 1295 bits (3352), Expect = 0.0
Identities = 665/1078 (61%), Positives = 813/1078 (75%), Gaps = 82/1078 (7%)
Query: 31 IHIGLPVPTYPQRKTDQK---GHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLI 87
I+IG+ VP +R+ K GH +K ++ + + ++ +SS ++
Sbjct: 29 IYIGVHVPKSYRRRRRHKRKTGHKEKKEK-------ERISENYSDKSDIENADESSSSIL 81
Query: 88 SRTRSPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEG 145
SPAAE+++ ILGEED++P P LFTE+D L DG +MEWKE+ARWIKFEEKVE+G
Sbjct: 82 KPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQG 141
Query: 146 GERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELR 205
GERWSKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+
Sbjct: 142 GERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELK 201
Query: 206 ERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSA 265
++V+Y LLR+HRHQTKK RSLADIGK+VS+ +R P++ H
Sbjct: 202 DKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR---------- 251
Query: 266 NYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRL 325
+ S S+NDIS P DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL
Sbjct: 252 ------NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRL 305
Query: 326 IQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNRED 385
Q+ MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R D
Sbjct: 306 QQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHD 365
Query: 386 LIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGA 445
LIAGIDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S E QMNG GG
Sbjct: 366 LIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH 425
Query: 446 PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRK 505
GGG+G EEL TGRF GGL DIKRK
Sbjct: 426 GGGGHGDC--------------------------------EELQRTGRFCGGLIKDIKRK 453
Query: 506 LPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGS 565
P+F SDFYD +IQ++SAILFIYL +TNAITFGGLLGDATDN QGV+ESFLGTA++G+
Sbjct: 454 APFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGA 513
Query: 566 LFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDA 625
+FCLF+GQPL ILSSTGP+L+FE+LLF+FSK N DY+EFRLWIGL SA CLILVATDA
Sbjct: 514 IFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDA 573
Query: 626 SFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPD 685
SF+++Y TRFTEEGFS+LISFIFIYDA KKMI YYPIN +FK + T + C CV PD
Sbjct: 574 SFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPD 633
Query: 686 TVNTTVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDL 743
N ++ N + LAP+ S ++ + T DW+ LSKKEC YGG L+GN+C F+PD+
Sbjct: 634 PANISISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692
Query: 744 ALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPK 803
LMSFILF GTY+ ++ LKKFK S YFPT R L++DF+I+ SIL+FC IDA G++TPK
Sbjct: 693 TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPK 752
Query: 804 LHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENK 863
L VPS KPT P+RGWFV PFG+NPWWV A+ +PALLVTILIFMDQQITAVIVNRKE+K
Sbjct: 753 LIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHK 812
Query: 864 LKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLG 923
LKK AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLG
Sbjct: 813 LKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLG 872
Query: 924 VREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQ 983
VREQRVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q
Sbjct: 873 VREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ----------- 921
Query: 984 KKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIF 1043
F +R KL LMP KHQPD +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIF
Sbjct: 922 -----FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIF 976
Query: 1044 PVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGA-HEDCDEE 1098
PVMIL L+ VR+ +D++FSQHDL+++D+++PEK+ KKE +KK+K+KKG+ D D+E
Sbjct: 977 PVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDE 1034
>gi|155722998 solute carrier family 4, sodium bicarbonate
transporter-like, member 10 [Homo sapiens]
Length = 1088
Score = 974 bits (2517), Expect = 0.0
Identities = 521/1105 (47%), Positives = 705/1105 (63%), Gaps = 115/1105 (10%)
Query: 44 KTDQKGHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMD--LISRTRSPA----AEQ 97
K D +GH + VH L + + G +D D L SP+ +++
Sbjct: 39 KEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQR 98
Query: 98 LQDILGEEDEAPNPT---LFTEMDTL-QHDGDQMEWKESARWIKFEEKVEEGGERWSKPH 153
+Q ILG ED+ LFTE+D + +G+ EW+E+ARW+KFEE VE+GGERWSKP+
Sbjct: 99 VQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPY 158
Query: 154 VSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLL 213
V+TLSLHSLFELR+C+ GTVLLD+ + +L +I D V+++Q+ G L ++R RV L+
Sbjct: 159 VATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALM 218
Query: 214 RRHRHQTKK------PIHRSLADIGKSVSTTNRSPAR-----SPGAGPSLHHSTEDLRMR 262
++H HQ +K PI RS ADIGK S N SP + P+ + D+
Sbjct: 219 KQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRE 278
Query: 263 QSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAF 322
S T + + FMKKIP +EASN+LVGE++FLD+ +AF
Sbjct: 279 NS-------------------TVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAF 319
Query: 323 VRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARN 382
VRL + +L G+ EVP+PTRFLFILLGP G+ + Y+EIGR+IATLM D++F DVAYKA++
Sbjct: 320 VRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKD 379
Query: 383 REDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGG 442
R DL++GIDEFLD+V VLPPGEWDP+IRIEPPK VPS +KRK NG+ G
Sbjct: 380 RNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIP------AVPNGTAAHG 433
Query: 443 GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDI 502
P GG+ G EL TGR FGGL LDI
Sbjct: 434 EAEPHGGHSG---------------------------------PELQRTGRIFGGLILDI 460
Query: 503 KRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAM 562
KRK P+F SDF D F +Q +++ LF+Y C++ ITFGGLLG+AT+ +ES G +M
Sbjct: 461 KRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASM 520
Query: 563 AGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVA 622
G + LF GQPL IL STGP+L+FEK+LF F K GL Y+ R IGL +A C+ILVA
Sbjct: 521 TGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVA 580
Query: 623 TDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECV 682
TDAS ++ YITRFTEE F++LI IFIY+A++K+ + YPINM +T Y C CV
Sbjct: 581 TDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCV 640
Query: 683 APDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSC----K 738
P + N + ++N S +++ W L+ EC S G +G +C
Sbjct: 641 EPHNPS----NGTLKEWRESNISASDII------WENLTVSECKSLHGEYVGRACGHDHP 690
Query: 739 FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFG 798
++PD+ S ILFF T +++ TLK+FK SRYFPTKVR++V+DF++ +IL ID G
Sbjct: 691 YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIG 750
Query: 799 LETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVN 858
+ +PKL VPSV KPTR DRGWFV P G NPWW A+I+PALL TILIFMDQQITAVI+N
Sbjct: 751 IPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN 810
Query: 859 RKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQ 918
RKE+KLKK GYHLDL V +++ +CS MGLPW+VAATV+SI H++SLK+E+E SAPGEQ
Sbjct: 811 RKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ 870
Query: 919 PQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGS 978
P+FLG+REQRVTG+++FIL G SVF+ ILK IP+PVLYGVFLYMG +SL GIQ
Sbjct: 871 PKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQ------ 924
Query: 979 EFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTV 1038
F++R KLF MPAKHQPD +LRHVPLR++HLFT++Q+ CL +LWI+K +
Sbjct: 925 ----------FFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSR 974
Query: 1039 AAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKETDKKRKRKKGAHEDCDEE 1098
AAI+FP+M+L L+ VR+L+D +F++ +L+W+D+++PE +KK+ + K ++ + ++E
Sbjct: 975 AAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDE 1034
Query: 1099 PQFPPPSVIKIPMESVQSDPQNGIH 1123
+++P+E D + I+
Sbjct: 1035 ------GTVQLPLEGHYRDDPSVIN 1053
>gi|90403614 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform a [Homo sapiens]
Length = 1093
Score = 966 bits (2498), Expect = 0.0
Identities = 514/1068 (48%), Positives = 695/1068 (65%), Gaps = 100/1068 (9%)
Query: 72 GPGSGASSQDSSMDLISRTRSPAAEQLQDILG-EEDEAPNP-TLFTEMDTL-QHDGDQME 128
G G GAS + ++ ++ ++++Q ILG EEDE P LFTE+D + +G+ E
Sbjct: 75 GRGKGASQGEEGLEALAH--DTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAE 132
Query: 129 WKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIID 188
WKE+ARW+KFEE VE+GGERWSKP+V+TLSLHSLFELR+CL GTVLLD+ + S+ +I D
Sbjct: 133 WKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISD 192
Query: 189 DVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSP 242
++++Q L +R +V LL++H HQ +K PI RS A++GK S +
Sbjct: 193 LILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMD 252
Query: 243 ARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDS 302
P +T +L ++ N C ++ + L FMKKIP +
Sbjct: 253 KHGQTVSPQSVPTT-NLEVKNGVN----CEHSPVDLSKVDL---------HFMKKIPTGA 298
Query: 303 EASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGR 362
EASNVLVGEVD LD+P +AFVRL + +L G+TEVP+PTRFLFILLGP G+ + Y+EIGR
Sbjct: 299 EASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGR 358
Query: 363 AIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADK 422
++AT+M D++F DVAYKA+ R+DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK VPS +K
Sbjct: 359 SMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEK 418
Query: 423 RKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482
RK G NG+V P GG+ G
Sbjct: 419 RKMP------GVPNGNVCHIEQEPHGGHSG------------------------------ 442
Query: 483 EIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGL 542
EL TGR FGGL LDIKRK PW+ SD+ D +Q +++ LF+Y C++ ITFGGL
Sbjct: 443 ---PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGL 499
Query: 543 LGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDY 602
LG+AT+ +ES G +M G + LF+GQ L IL STGP+L+FEK+LF F K L Y
Sbjct: 500 LGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSY 559
Query: 603 MEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKY 662
+ R IGL +A C++LVATDAS ++ YITRFTEE F++LI IFIY+AI+K+I +
Sbjct: 560 LSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAET 619
Query: 663 YPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSK 722
YPI+M + + ++ Y C C P+ N N + D N + + W+ L+
Sbjct: 620 YPIHMHSQLDHLSLYYCRCTLPENPN----NHTLQYWKDHN------IVTAEVHWANLTV 669
Query: 723 KECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALV 778
EC G +G++C + PD+ S ILFF T+ ++ TLK FK SRYFPT+VR++V
Sbjct: 670 SECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMV 729
Query: 779 ADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILP 838
+DF++ +I ID G+ +PKL VPSV KPTR DRGW + P G NPWW A+I+P
Sbjct: 730 SDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIP 789
Query: 839 ALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVI 898
ALL TILIFMDQQITAVI+NRKE+KLKK GYHLDL V I++ +CS MGLPW+VAATV+
Sbjct: 790 ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849
Query: 899 SIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYG 958
SI H++SLK+E+E SAPGEQP+FLG+REQRVTG+++F+L G SVF+ ILK IP+PVLYG
Sbjct: 850 SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909
Query: 959 VFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIH 1018
VFLYMGV+SL GIQ F++R KLF MPAKHQPD +LRHVPLR++H
Sbjct: 910 VFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVH 953
Query: 1019 LFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEK 1078
LFTL+Q+ CL +LW++K++ AAI+FP+M+L L+ VR+++D FS+ +L+W+D+++PE +K
Sbjct: 954 LFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKK 1013
Query: 1079 KETDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMES--VQSDPQNGIHC 1124
K+ D +K+ K + +E + K P+ES + S P I C
Sbjct: 1014 KKLDDAKKKAK----EEEEAEKMLEIGGDKFPLESRKLLSSPGKNISC 1057
>gi|90568034 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform b [Homo sapiens]
Length = 1044
Score = 964 bits (2492), Expect = 0.0
Identities = 505/1031 (48%), Positives = 681/1031 (66%), Gaps = 94/1031 (9%)
Query: 72 GPGSGASSQDSSMDLISRTRSPAAEQLQDILG-EEDEAPNP-TLFTEMDTL-QHDGDQME 128
G G GAS + ++ ++ ++++Q ILG EEDE P LFTE+D + +G+ E
Sbjct: 75 GRGKGASQGEEGLEALAH--DTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAE 132
Query: 129 WKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIID 188
WKE+ARW+KFEE VE+GGERWSKP+V+TLSLHSLFELR+CL GTVLLD+ + S+ +I D
Sbjct: 133 WKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISD 192
Query: 189 DVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSP 242
++++Q L +R +V LL++H HQ +K PI RS A++GK S +
Sbjct: 193 LILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMD 252
Query: 243 ARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDS 302
P +T +L ++ N C ++ + L FMKKIP +
Sbjct: 253 KHGQTVSPQSVPTT-NLEVKNGVN----CEHSPVDLSKVDL---------HFMKKIPTGA 298
Query: 303 EASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGR 362
EASNVLVGEVD LD+P +AFVRL + +L G+TEVP+PTRFLFILLGP G+ + Y+EIGR
Sbjct: 299 EASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGR 358
Query: 363 AIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADK 422
++AT+M D++F DVAYKA+ R+DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK VPS +K
Sbjct: 359 SMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEK 418
Query: 423 RKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482
RK G NG+V P GG+ G
Sbjct: 419 RKMP------GVPNGNVCHIEQEPHGGHSG------------------------------ 442
Query: 483 EIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGL 542
EL TGR FGGL LDIKRK PW+ SD+ D +Q +++ LF+Y C++ ITFGGL
Sbjct: 443 ---PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGL 499
Query: 543 LGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDY 602
LG+AT+ +ES G +M G + LF+GQ L IL STGP+L+FEK+LF F K L Y
Sbjct: 500 LGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSY 559
Query: 603 MEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKY 662
+ R IGL +A C++LVATDAS ++ YITRFTEE F++LI IFIY+AI+K+I +
Sbjct: 560 LSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAET 619
Query: 663 YPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSK 722
YPI+M + + ++ Y C C P+ N N + D N + + W+ L+
Sbjct: 620 YPIHMHSQLDHLSLYYCRCTLPENPN----NHTLQYWKDHN------IVTAEVHWANLTV 669
Query: 723 KECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALV 778
EC G +G++C + PD+ S ILFF T+ ++ TLK FK SRYFPT+VR++V
Sbjct: 670 SECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMV 729
Query: 779 ADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILP 838
+DF++ +I ID G+ +PKL VPSV KPTR DRGW + P G NPWW A+I+P
Sbjct: 730 SDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIP 789
Query: 839 ALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVI 898
ALL TILIFMDQQITAVI+NRKE+KLKK GYHLDL V I++ +CS MGLPW+VAATV+
Sbjct: 790 ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849
Query: 899 SIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYG 958
SI H++SLK+E+E SAPGEQP+FLG+REQRVTG+++F+L G SVF+ ILK IP+PVLYG
Sbjct: 850 SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909
Query: 959 VFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIH 1018
VFLYMGV+SL GIQ F++R KLF MPAKHQPD +LRHVPLR++H
Sbjct: 910 VFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVH 953
Query: 1019 LFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEK 1078
LFTL+Q+ CL +LW++K++ AAI+FP+M+L L+ VR+++D FS+ +L+W+D+++PE +K
Sbjct: 954 LFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKK 1013
Query: 1079 KETDKKRKRKK 1089
K+ D +K+ K
Sbjct: 1014 KKLDDAKKKAK 1024
>gi|151101449 solute carrier family 4, sodium bicarbonate
cotransporter, member 9 [Homo sapiens]
Length = 959
Score = 842 bits (2174), Expect = 0.0
Identities = 466/993 (46%), Positives = 607/993 (61%), Gaps = 102/993 (10%)
Query: 93 PAAEQLQDILGEEDEAP-NPTLFTEMDTLQHDGDQMEWKESARWIKFEEKVEEGGERWSK 151
P+ + D +E P +P LF +++ L +EW+E+ RW+ FEEK+E RWS
Sbjct: 35 PSPDGPSDTESKELGVPKDPLLFIQLNELLGWPQALEWRETGRWVLFEEKLEVAAGRWSA 94
Query: 152 PHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYV 211
PHV TL+L SL +LR+ L G VLLD + SL ++++ V + L PELR ++ +
Sbjct: 95 PHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVES----LSPELRGQLQAL 150
Query: 212 LLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGRLC 271
LL+R +H + TT P S H
Sbjct: 151 LLQRPQHYNQ---------------TTGTRPCWG-----STH------------------ 172
Query: 272 HAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAML 331
R +D P +Q +N +K+P +EA VL GE+ FL QP AFVRL +L
Sbjct: 173 ---PRKASDNEEAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVL 229
Query: 332 GGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGID 391
G +TEV +P+RF +LLGP K Y+E+GRA A L+ D F +A N DL+A +D
Sbjct: 230 GSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALD 289
Query: 392 EFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNG 451
FL+EV VLPPG WDP RI PPK +PS KR L + G
Sbjct: 290 AFLEEVTVLPPGRWDPTARIPPPKCLPSQHKR--------LPSQQREIRGPA-------- 333
Query: 452 GGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPS 511
+S +D H EL TGR FGGL D++RK+PW+PS
Sbjct: 334 ---------------VPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPS 378
Query: 512 DFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFS 571
DF D H+Q SA+L+IYL +TNAITFGGLLGDATD QGV+ESFLGTA+AG+ FCL +
Sbjct: 379 DFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMA 438
Query: 572 GQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKY 631
GQPL ILSSTGP+L+FE+LLF FS+ LDY+ FRLW+G+ A CL+LVAT+AS +++Y
Sbjct: 439 GQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRY 498
Query: 632 ITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTV-NTT 690
TRFTEEGF LIS IFIYDA+ KM+ YPI KP + Y C C P N +
Sbjct: 499 FTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPGS-SAYGCLCQYPGPGGNES 554
Query: 691 VFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFIL 750
+ + P D S+ +L ++ SLL EC GG G C +PD+A S +L
Sbjct: 555 QWIRTRPKDRDDIVSM----DLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLL 610
Query: 751 FFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVPSVI 810
F ++ + LK K SR+FP+ VR ++DFS V +IL+ CG+DA GL TPKL VP
Sbjct: 611 FLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREF 670
Query: 811 KPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGY 870
KPT P RGW V+PFG NPWW A+ LPALL++ILIFMDQQITAVI+NR E +L+K AG+
Sbjct: 671 KPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGF 730
Query: 871 HLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVT 930
HLDLF V +LM L S +GLPWYV+ATVIS+AH+DSL+ E+ APGE+P FLG+REQR+T
Sbjct: 731 HLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLT 790
Query: 931 GIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFW 990
G++VFILTG S+FLAP+LK IP+PVLYG+FLYMGVA+L+ IQ F
Sbjct: 791 GLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQ----------------FT 834
Query: 991 ERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGL 1050
R KL LMPAKHQPD LRHVPL R+HLFT +Q+ CL +LWI+KST AAIIFP+M+LGL
Sbjct: 835 NRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGL 894
Query: 1051 IIVRRLLDFIFSQHDLAWIDNILPEKEKKETDK 1083
+ VR+ L+ +FS +L W+D ++PE+E+ +K
Sbjct: 895 VGVRKALERVFSPQELLWLDELMPEEERSIPEK 927
>gi|134288865 solute carrier family 4, sodium bicarbonate
cotransporter, member 7 [Homo sapiens]
Length = 1214
Score = 821 bits (2121), Expect = 0.0
Identities = 419/842 (49%), Positives = 573/842 (68%), Gaps = 79/842 (9%)
Query: 294 FMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGR 353
FM+KIP +EASNVLVGEVDFL++P IAFVRL + +L G+TEVPVPTRFLF+LLGP+G+
Sbjct: 418 FMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGK 477
Query: 354 AKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEP 413
A Y+EIGR+IATLM D++F DVAYKA++R DL++GIDEFLD+V VLPPGEWDP+IRIEP
Sbjct: 478 APQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEP 537
Query: 414 PKKVPSADKRK-SVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
PK VPS +KRK VF NGS G P
Sbjct: 538 PKSVPSQEKRKIPVFH-------NGSTPTLGETP-------------------------- 564
Query: 473 GDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGC 532
A H G EL TGR FGGL LDIKRK P+F SDF D +Q +++ILF+Y C
Sbjct: 565 -----KEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCAC 619
Query: 533 ITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLF 592
++ ITFGGLLG+AT+ +ES G ++ G + LF+GQPL IL STGP+L+FEK+L+
Sbjct: 620 MSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILY 679
Query: 593 DFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDA 652
F + L Y+ R IGL ++ C++LVATDAS ++ YITRFTEE F+ LI IFIY+A
Sbjct: 680 KFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEA 739
Query: 653 IKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNL 712
++K+ + Y NM + +T+Y C C P P + + + N+
Sbjct: 740 LEKLFDLGETYAFNMHNNLDKLTSYSCVCTEP------------PNPSNETLAQWKKDNI 787
Query: 713 TA--LDWSLLSKKECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKF 766
TA + W L+ EC G LG++C +IPD+ ILFF T+ ++ LK+FK
Sbjct: 788 TAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKT 847
Query: 767 SRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGK 826
RYFPTKVR+ ++DF++ +I++ ID G+ +PKLHVP +PT P+RGW ++P G
Sbjct: 848 KRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGD 907
Query: 827 NPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSF 886
NPWW + +PALL TILIFMDQQITAVI+NRKE+KLKK AGYHLDL VG+++ +CS
Sbjct: 908 NPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSV 967
Query: 887 MGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAP 946
MGLPW+VAATV+SI+H++SLK+E+E SAPGEQP+FLG+REQRVTG+++FIL G+SVF+
Sbjct: 968 MGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTS 1027
Query: 947 ILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDH 1006
+LK IP+PVLYGVFLYMGV+SL GIQ+ ++R KLF MPAKHQPD
Sbjct: 1028 VLKFIPMPVLYGVFLYMGVSSLKGIQL----------------FDRIKLFGMPAKHQPDL 1071
Query: 1007 AFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDL 1066
+LR+VPL ++H+FT++Q+ CL +LW++K + AA++FP+M+L L+ VR+L+D F++ +L
Sbjct: 1072 IYLRYVPLWKVHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKREL 1131
Query: 1067 AWIDNILPE-KEKKETDKKRKRKKGAH---EDCDEEPQFP--PPSVIKIPMESVQSDPQN 1120
+W+D+++PE K+KKE DKK+K K+ A +D D+ P S+++IP+++++ P
Sbjct: 1132 SWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDDDTVHLPFEGGSLLQIPVKALKYSPDK 1191
Query: 1121 GI 1122
+
Sbjct: 1192 PV 1193
Score = 154 bits (389), Expect = 5e-37
Identities = 96/235 (40%), Positives = 132/235 (56%), Gaps = 30/235 (12%)
Query: 31 IHIGLPVPTYPQ--RKTDQKGHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLIS 88
++IG+ VP + R+ +GH K H R D+ + G S + S
Sbjct: 43 VYIGVHVPFSKESRRRHRHRGH-----KHHHRRRKDKESDKEDGRESPSYDTPS------ 91
Query: 89 RTRSPAAEQLQDILGEEDEAPNPT---LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEE 144
+++Q ILG ED+ LFTEMD L + DG++ EWKE+ARW+KFEE VE+
Sbjct: 92 -------QRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVED 144
Query: 145 GGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPEL 204
GG+RWSKP+V+TLSLHSLFELR+C+ GTV+LD+ + +L +I D V++ I G L +
Sbjct: 145 GGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESI 204
Query: 205 RERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSPARSPGAGPSLH 253
RE V LL+RH HQ +K P+ RS ADIGK S + G S H
Sbjct: 205 RENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRH 259
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 598 bits (1541), Expect = e-170
Identities = 369/976 (37%), Positives = 536/976 (54%), Gaps = 103/976 (10%)
Query: 113 LFTEMDTLQHDGDQM-EWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQT 171
+F E++ L D Q W+E+ARWIKFEE VEE ERW KPHV++LS SL ELR +
Sbjct: 321 VFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 380
Query: 172 GTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIH 225
G LLDL+ +LP I V+E I +RPE R V LL +H H P +
Sbjct: 381 GAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRN 440
Query: 226 RSLADIGKSVSTTNRSPARSP-GAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLT 284
S + + + + +P+ P GA P++ +DL + + A+ + ++
Sbjct: 441 PSSSSMNSVLGNHHPTPSHGPDGAVPTM---ADDLG-EPAPLWPHDPDAKEKPLH----M 492
Query: 285 PNTDQRKNKFMK---KIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPT 341
P D + K +K KIP+D+EA+ VLVG V FL+QP AFVRL ++ +L V EVPVP
Sbjct: 493 PGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPV 552
Query: 342 RFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLP 401
RFLF++LGPS + Y+E+GR+IATLM D LF + AY+A +R+DL++ I EFLD IV+P
Sbjct: 553 RFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIP 612
Query: 402 PGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGG 461
P E + + RK E ++ + GG APG
Sbjct: 613 PSEVEGRDLLRSVAAFQRELLRKR--REREQTKVEMTTRGGYTAPG----------KELS 660
Query: 462 AGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQS 521
GG+ T D L+ TG FGGL D++R+ P +PSD D H Q
Sbjct: 661 LELGGSEATPEDDP------------LLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQC 708
Query: 522 ISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSST 581
++A+LFIY ++ AITFGGLLG+ T+ GV E + TA+ G LF L QPL+++ +
Sbjct: 709 VAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFS 768
Query: 582 GPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFS 641
GP+L+FE+ F F + L+Y+ R+W+GL V L LVA + SF+++YI+ FT+E F+
Sbjct: 769 GPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFA 828
Query: 642 TLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPD 701
LIS IFIY+ K+ F +P+ + Y E +++ + + L P
Sbjct: 829 FLISLIFIYETFYKLYKVFTEHPL--------LPFYPPEGALEGSLDAGLEPNGSALPPT 880
Query: 702 TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTL 761
S + P+ AL+S IL GT+ + L
Sbjct: 881 EGPP------------------------------SPRNQPNTALLSLILMLGTFFIAFFL 910
Query: 762 KKFKFSRYFPTKVRALVADFSIVFSILMFCGID-ACFGLETPKLHVPSVIKPTRPD-RGW 819
+KF+ SR+ K R ++ DF I SIL+ +D + T KL VP+ + T PD R W
Sbjct: 911 RKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSW 970
Query: 820 FVAPFGKN---PWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFW 876
F+ P G P W+ A+ +PALLV ILIFM+ QITA+IV++K +L K +G+HLDL
Sbjct: 971 FIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLL 1030
Query: 877 VGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFI 936
+G L LC GLPW AATV S+ H+++L + APG++PQ VREQRVTG+++
Sbjct: 1031 IGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIAS 1090
Query: 937 LTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLF 996
L G+S+ + +L+ IPL VL+G+FLYMGV SL+GIQ+ +R L
Sbjct: 1091 LVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLS----------------QRLLLI 1134
Query: 997 LMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRR- 1055
LMPAKH P+ ++ V R+HLFT +Q+ C+A+LW++KST A++ FP ++L + +R
Sbjct: 1135 LMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHC 1194
Query: 1056 LLDFIFSQHDLAWIDN 1071
LL +F +L +D+
Sbjct: 1195 LLPRLFQDRELQALDS 1210
>gi|157671953 solute carrier family 4, anion exchanger, member 3
isoform 2 [Homo sapiens]
Length = 1259
Score = 598 bits (1541), Expect = e-170
Identities = 369/976 (37%), Positives = 536/976 (54%), Gaps = 103/976 (10%)
Query: 113 LFTEMDTLQHDGDQM-EWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQT 171
+F E++ L D Q W+E+ARWIKFEE VEE ERW KPHV++LS SL ELR +
Sbjct: 348 VFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 407
Query: 172 GTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIH 225
G LLDL+ +LP I V+E I +RPE R V LL +H H P +
Sbjct: 408 GAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRN 467
Query: 226 RSLADIGKSVSTTNRSPARSP-GAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLT 284
S + + + + +P+ P GA P++ +DL + + A+ + ++
Sbjct: 468 PSSSSMNSVLGNHHPTPSHGPDGAVPTM---ADDLG-EPAPLWPHDPDAKEKPLH----M 519
Query: 285 PNTDQRKNKFMK---KIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPT 341
P D + K +K KIP+D+EA+ VLVG V FL+QP AFVRL ++ +L V EVPVP
Sbjct: 520 PGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPV 579
Query: 342 RFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLP 401
RFLF++LGPS + Y+E+GR+IATLM D LF + AY+A +R+DL++ I EFLD IV+P
Sbjct: 580 RFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIP 639
Query: 402 PGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGG 461
P E + + RK E ++ + GG APG
Sbjct: 640 PSEVEGRDLLRSVAAFQRELLRKR--REREQTKVEMTTRGGYTAPG----------KELS 687
Query: 462 AGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQS 521
GG+ T D L+ TG FGGL D++R+ P +PSD D H Q
Sbjct: 688 LELGGSEATPEDDP------------LLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQC 735
Query: 522 ISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSST 581
++A+LFIY ++ AITFGGLLG+ T+ GV E + TA+ G LF L QPL+++ +
Sbjct: 736 VAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFS 795
Query: 582 GPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFS 641
GP+L+FE+ F F + L+Y+ R+W+GL V L LVA + SF+++YI+ FT+E F+
Sbjct: 796 GPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFA 855
Query: 642 TLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPD 701
LIS IFIY+ K+ F +P+ + Y E +++ + + L P
Sbjct: 856 FLISLIFIYETFYKLYKVFTEHPL--------LPFYPPEGALEGSLDAGLEPNGSALPPT 907
Query: 702 TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTL 761
S + P+ AL+S IL GT+ + L
Sbjct: 908 EGPP------------------------------SPRNQPNTALLSLILMLGTFFIAFFL 937
Query: 762 KKFKFSRYFPTKVRALVADFSIVFSILMFCGID-ACFGLETPKLHVPSVIKPTRPD-RGW 819
+KF+ SR+ K R ++ DF I SIL+ +D + T KL VP+ + T PD R W
Sbjct: 938 RKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSW 997
Query: 820 FVAPFGKN---PWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFW 876
F+ P G P W+ A+ +PALLV ILIFM+ QITA+IV++K +L K +G+HLDL
Sbjct: 998 FIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLL 1057
Query: 877 VGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFI 936
+G L LC GLPW AATV S+ H+++L + APG++PQ VREQRVTG+++
Sbjct: 1058 IGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIAS 1117
Query: 937 LTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLF 996
L G+S+ + +L+ IPL VL+G+FLYMGV SL+GIQ+ +R L
Sbjct: 1118 LVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLS----------------QRLLLI 1161
Query: 997 LMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRR- 1055
LMPAKH P+ ++ V R+HLFT +Q+ C+A+LW++KST A++ FP ++L + +R
Sbjct: 1162 LMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHC 1221
Query: 1056 LLDFIFSQHDLAWIDN 1071
LL +F +L +D+
Sbjct: 1222 LLPRLFQDRELQALDS 1237
>gi|156071474 solute carrier family 4, anion exchanger, member 2
(erythrocyte membrane protein band 3-like 1) [Homo
sapiens]
Length = 1241
Score = 593 bits (1529), Expect = e-169
Identities = 369/1003 (36%), Positives = 550/1003 (54%), Gaps = 120/1003 (11%)
Query: 103 GEEDEAPNPT-------------LFTEMDTLQHDGDQM-EWKESARWIKFEEKVEEGGER 148
G E P PT +F E++ L D +Q +W+E+ARWIKFEE VEE ER
Sbjct: 300 GREGREPGPTPRARPRAPHKPHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETER 359
Query: 149 WSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERV 208
W KPHV++LS SL ELR L G VLLDLD +LP + V+E+ + ++ E R V
Sbjct: 360 WGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANV 419
Query: 209 SYVLLRRHRHQTKK-----PIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQ 263
LL +H H + + P + S +G + + A S H TE L
Sbjct: 420 LRALLLKHSHPSDEKDFSFPRNISAGSLGSLLGHHHGQGAESDP------HVTEPLM--G 471
Query: 264 SANYGRLCHAQSRSMND----ISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPF 319
RL + R + +T + + + K ++KIP+++EA+ VLVG V+FL +P
Sbjct: 472 GVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPT 531
Query: 320 IAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYK 379
+AFVRL ++ L V EVPVP RFLF+LLGPS Y+EIGR+I+TLM D F + AY
Sbjct: 532 MAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYL 591
Query: 380 ARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSV 439
A REDL+ I+ FLD +VLPP E ++ E + + +R+ + E G++
Sbjct: 592 ADEREDLLTAINAFLDCSVVLPPSE----VQGEELLRSVAHFQRQMLKKREEQGRL---- 643
Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIG----EELIWTGRFF 495
P G G S+ D + + G + L TGR F
Sbjct: 644 -----LPTGA----------------GLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPF 682
Query: 496 GGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVME 555
GGL D++R+ P + SDF D Q ++A++FIY ++ AITFGGLLG+ T + GV E
Sbjct: 683 GGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSE 742
Query: 556 SFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAV 615
+ TA+ G +FCL QPL+++ +GP+L+FE+ F F N L+Y+ R+WIG
Sbjct: 743 LIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVF 802
Query: 616 QCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFIT 675
L++VA + SF++++++RFT+E F+ LIS IFIY+ K++ F+ +P++ N
Sbjct: 803 LALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCSASNSSE 862
Query: 676 TYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGN 735
E N T A L P S G+
Sbjct: 863 VDGGE-------NMTWAGARPTLGPGNR-----------------------SLAGQSGQG 892
Query: 736 SCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDA 795
+ P+ AL+S +L GT+ + L+KFK SR+FP ++R ++ DF + +IL+ +D
Sbjct: 893 KPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVD- 951
Query: 796 CFGLE---TPKLHVPSVIKPTRPD-RGWFVAPFGKN---PWWVYPASILPALLVTILIFM 848
+ +E T KL VPS T P+ RGW + P G+ P W+ AS+LPA+LV ILIFM
Sbjct: 952 -YSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFM 1010
Query: 849 DQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKM 908
+ QIT +I+++KE L+K +G+HLDL + + +C+ GLPW AATV S+ H ++L +
Sbjct: 1011 ETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTV 1070
Query: 909 ETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASL 968
++ APG++P+ V+EQRVTG++V +L G+S+ + +L+ IPL VL+G+FLYMGV SL
Sbjct: 1071 MSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSL 1130
Query: 969 NGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCL 1028
NGIQ F+ER L LMP KH PD +++ V R+HLFT +Q+LCL
Sbjct: 1131 NGIQ----------------FYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCL 1174
Query: 1029 AVLWILKSTVAAIIFP-VMILGLIIVRRLLDFIFSQHDLAWID 1070
A+LW + ST A++ FP ++IL + + +L IF+ ++ +D
Sbjct: 1175 ALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKCLD 1217
>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
sapiens]
Length = 911
Score = 525 bits (1351), Expect = e-148
Identities = 345/998 (34%), Positives = 515/998 (51%), Gaps = 154/998 (15%)
Query: 88 SRTRSPAAEQLQDILGEEDEAPNP---TLFTEMDTLQHD--GDQMEWKESARWIKFEEKV 142
S+ PAA + + +P ++ E+ L D ++ W E+ARW++ EE +
Sbjct: 29 SQMEEPAAHDTEATATDYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENL 88
Query: 143 EEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRP 202
E G W +PH+S L+ SL ELR GTVLLDL SL + + ++++ I + +RP
Sbjct: 89 GENGA-WGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRP 147
Query: 203 ELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSL--HHSTEDLR 260
+ RE + LL +H H + +L + +V T + P++ P L H S E
Sbjct: 148 QDREELLRALLLKHSHAGEL---EALGGVKPAVLTRSGDPSQ-----PLLPQHSSLETQL 199
Query: 261 MRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFI 320
+ + G H+ S ++KIP DSEA+ VLVG DFL+QP +
Sbjct: 200 FCEQGDGGTEGHSPSG-----------------ILEKIPPDSEATLVLVGRADFLEQPVL 242
Query: 321 AFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKA 380
FVRL ++A L V E+PVP RFLF+LLGP Y ++GRA ATLM + +F AY A
Sbjct: 243 GFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMA 301
Query: 381 RNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQ--MNGS 438
++R +L+ ++ FLD +VL PP PS +++ SL + + +
Sbjct: 302 QSRGELLHSLEGFLDCSLVL------------PPTDAPS---EQALLSLVPVQRELLRRR 346
Query: 439 VGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGL 498
P S G GG + L TG+ FGGL
Sbjct: 347 YQSSPAKPD----------SSFYKGLDLNGGPD--------------DPLQQTGQLFGGL 382
Query: 499 CLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFL 558
DI+R+ P++ SD D F Q ++A++FIY ++ AITFGGLLG+ T N GV E +
Sbjct: 383 VRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLI 442
Query: 559 GTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCL 618
TA+ G LF L QPL+++ +GP+L+FE+ F F + NGL+Y+ R+WIG + +
Sbjct: 443 STAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVV 502
Query: 619 ILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYK 678
++VA + SF++++I+R+T+E FS LIS IFIY+ K+I F+ +P+
Sbjct: 503 LVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQK----------- 551
Query: 679 CECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCK 738
T N V P P
Sbjct: 552 -------TYNYNVLMVPKPQGP-------------------------------------- 566
Query: 739 FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACF- 797
+P+ AL+S +L GT+ + L+KFK S YFP K+R ++ DF + SIL+ +D
Sbjct: 567 -LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQ 625
Query: 798 GLETPKLHVPSVIKPTRPD-RGWFVAPFGKN---PWWVYPASILPALLVTILIFMDQQIT 853
T KL VP K + RGW + P G P W+ AS LPALLV ILIF++ QIT
Sbjct: 626 DTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQIT 685
Query: 854 AVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETS 913
+IV++ E K+ K +G+HLDL V + + + G+PW A TV S+ H ++L + + S
Sbjct: 686 TLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKAS 745
Query: 914 APGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQM 973
PG Q V+EQR++G++V +L G+S+ + PIL IPL VL+G+FLYMGV SL+GIQ+
Sbjct: 746 TPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQL 805
Query: 974 GTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWI 1033
++R L P K+ PD +++ V R+HLFT +QI+CLAVLW+
Sbjct: 806 ----------------FDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWV 849
Query: 1034 LKSTVAAIIFP-VMILGLIIVRRLLDFIFSQHDLAWID 1070
+KST A++ P V+IL + + R LL IF +L +D
Sbjct: 850 VKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD 887
>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
Length = 891
Score = 212 bits (539), Expect = 2e-54
Identities = 162/576 (28%), Positives = 274/576 (47%), Gaps = 57/576 (9%)
Query: 494 FFGGLCLDIKRKLPWFPSDFYDGFHIQS------ISAILFIYLGCITNAITFGGLLGDAT 547
F G+ DI R+ P +P DF DG ++ I+ LF+Y C+ I FG L + T
Sbjct: 342 FGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENT 401
Query: 548 DNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRL 607
D V ++ G ++ G L+ LFSGQPL+IL +T P+ ++ +++ LD+ F
Sbjct: 402 DGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYA 461
Query: 608 WIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF-KYYPIN 666
W GL ++ + + S ++ R TEE + IS F+ DA+K + F KYY
Sbjct: 462 WTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYY--- 518
Query: 667 MDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECL 726
+++ Y T T+ + + L NASL+ LN + L + ++
Sbjct: 519 ---YGHYLDDY-------HTKRTSSLVSLSGLGASLNASLHTALNASFL--ASPTELPSA 566
Query: 727 SYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFS 786
++ G+ A++S ++ GT + TL +FK S Y VR +++D ++ +
Sbjct: 567 THSGQA----------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIA 616
Query: 787 ILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILI 846
+L F I + G ++ S + + + +A ++ L+++L
Sbjct: 617 VLAFSLISS-HGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLF 672
Query: 847 FMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSL 906
F++Q + A +VN EN+L K YH DL + I+ S GLPW AA S H+ +L
Sbjct: 673 FIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRAL 732
Query: 907 KMETETSAPGE-QPQFLGVREQRVTGIIVFILTGISVFLAPI-LKCIPLPVLYGVFLYMG 964
+ E G + V+E R+T + +L G+S+ L P+ L+ IP PVLYG+FLY+
Sbjct: 733 ALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIA 792
Query: 965 VASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFT--- 1021
+ SL+G Q+ +R L L P ++R VP R+IH FT
Sbjct: 793 LTSLDGNQL----------------VQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQ 836
Query: 1022 LVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLL 1057
++Q+L L + +IFP++++ +I +R +L
Sbjct: 837 VLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYIL 872
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 60.1 bits (144), Expect = 1e-08
Identities = 32/65 (49%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTG 492
G G+ GGG G+ GGG+GGG GGGSG GSGG+ G SG GE + GEE +G
Sbjct: 552 GGSGGNYGGGSGS-GGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSG 610
Query: 493 RFFGG 497
+GG
Sbjct: 611 GGYGG 615
Score = 53.9 bits (128), Expect = 8e-07
Identities = 26/44 (59%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G GS GGG G+ GGG+GGG GGGSGGG G GG S G G
Sbjct: 514 GGSGGSYGGGSGS-GGGSGGGYGGGSGGGHSGGSGGGHSGGSGG 556
Score = 52.8 bits (125), Expect = 2e-06
Identities = 25/46 (54%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGSGGAGGTSSGDDG 476
G +GS GG GG+ GGG+G GG GGG GGG+G G +GG+ G G
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552
Score = 52.0 bits (123), Expect = 3e-06
Identities = 26/44 (59%), Positives = 29/44 (65%), Gaps = 1/44 (2%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G +GS GG GG GGG+GGG GGSGGG SGG+GG G G
Sbjct: 521 GGGSGSGGGSGGGYGGGSGGGHSGGSGGG-HSGGSGGNYGGGSG 563
Score = 52.0 bits (123), Expect = 3e-06
Identities = 25/50 (50%), Positives = 26/50 (52%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482
G G GG GG GG+GG GGGSG G GSGG G SG G H
Sbjct: 537 GSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSH 586
Score = 50.8 bits (120), Expect = 7e-06
Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 6/66 (9%)
Query: 433 GQMNGSVGGGGGAPGGGNGG-GGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWT 491
G G GGG G+ GG G GGG GSGGG+G G GG+ G G H G +
Sbjct: 500 GGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGG-----S 554
Query: 492 GRFFGG 497
G +GG
Sbjct: 555 GGNYGG 560
Score = 49.7 bits (117), Expect = 2e-05
Identities = 25/41 (60%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 437 GSVGGGGGA-PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
GS GG GG+ GGG+GGG GGGSG GSGG+ G SG G
Sbjct: 488 GSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528
Score = 49.7 bits (117), Expect = 2e-05
Identities = 22/41 (53%), Positives = 25/41 (60%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
G GS GG GG GGG+ GG GGG GG+G GG+ SG
Sbjct: 525 GSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSG 565
Score = 45.8 bits (107), Expect = 2e-04
Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 6/68 (8%)
Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG------EMPA 480
F A G + S G GGG GG GG GGG G G GG GG + G DG E
Sbjct: 97 FGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKST 156
Query: 481 MHEIGEEL 488
M E+ L
Sbjct: 157 MQELNSRL 164
Score = 45.4 bits (106), Expect = 3e-04
Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGSGGAGGTSSGDDGE 477
G +GS GG GG+ GGG+G GG GG GGG + G+GG G G+
Sbjct: 573 GGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGK 619
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/40 (50%), Positives = 22/40 (55%)
Query: 437 GSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G GG GG+ G G+ GG GG GGG GG GG S G
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515
Score = 43.5 bits (101), Expect = 0.001
Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 3/47 (6%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGS-GGAGGTSSGDDG 476
G GS G G GG+ GGG GGG GGG+GS GG+GG+ G G
Sbjct: 479 GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG 525
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/56 (50%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 427 FSLAELGQMNGSVGGG----GGAPGGGNGGGGGGGSGGGAGSGG--AGGTSSGDDG 476
FS + LG G GGG GGA GGG GG G G G GSGG GG SG G
Sbjct: 81 FSASSLG---GGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGG 133
Score = 38.9 bits (89), Expect = 0.028
Identities = 19/37 (51%), Positives = 21/37 (56%)
Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G GGG GGG GGGS G G+ G G +SSG G
Sbjct: 76 GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFG 112
Score = 37.4 bits (85), Expect = 0.082
Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 4/53 (7%)
Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGGGG----GGSGGGAGSGGAGGTSSGDDG 476
+L E GQ + G G GG GG GG G GG GS G GG+ G G
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGG 508
Score = 37.0 bits (84), Expect = 0.11
Identities = 18/36 (50%), Positives = 20/36 (55%)
Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
GGGG+ G GGG GGG + GG GG S G G
Sbjct: 64 GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGG 99
Score = 34.3 bits (77), Expect = 0.69
Identities = 18/44 (40%), Positives = 20/44 (45%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G G GGG + GG GGG G G SGG +S G G
Sbjct: 70 GYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGG 113
Score = 33.9 bits (76), Expect = 0.90
Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 27/96 (28%)
Query: 427 FSLAELGQMNGSVGGGGGAPGGGN-----------GGGGGGGS-------GGGA------ 462
FS + L + G GGGGG GG+ GGGGGGG GGG+
Sbjct: 6 FSSSYLSRSGG--GGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGR 63
Query: 463 GSGGAGGTS-SGDDGEMPAMHEIGEELIWTGRFFGG 497
G GG+ G S G G + +G R FGG
Sbjct: 64 GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGG 99
Score = 32.3 bits (72), Expect = 2.6
Identities = 17/32 (53%), Positives = 20/32 (62%), Gaps = 2/32 (6%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGS 464
G+ GS GGG A G+GGG GGGSG + S
Sbjct: 594 GESGGSYGGGEEA--SGSGGGYGGGSGKSSHS 623
Score = 30.4 bits (67), Expect = 10.0
Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 8/51 (15%)
Query: 434 QMNGSVGGGGGAPGGGNGGGGGG--------GSGGGAGSGGAGGTSSGDDG 476
Q + S G GGG G GG S GG G GG +SSG G
Sbjct: 5 QFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGG 55
>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
sapiens]
Length = 419
Score = 58.9 bits (141), Expect = 3e-08
Identities = 29/53 (54%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIG 485
G G GGGG PGGG GGGGGGG GGG G G GG G P MH +G
Sbjct: 146 GPGGGGGPGGGGGPGGGPGGGGGGGPGGG-GGGPGGGLLGGSAHPHPHMHSLG 197
Score = 51.2 bits (121), Expect = 5e-06
Identities = 25/55 (45%), Positives = 28/55 (50%)
Query: 425 SVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMP 479
S+ +A G + GGGG G G GGG GGG G G G GG GG G G P
Sbjct: 124 SLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGP 178
Score = 43.1 bits (100), Expect = 0.001
Identities = 22/49 (44%), Positives = 23/49 (46%)
Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
S L M G+ G G A GGG G GGG G G G G GG G G
Sbjct: 121 SSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGG 169
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 57.4 bits (137), Expect = 8e-08
Identities = 32/57 (56%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
Query: 413 PPKKVPSADKRKSVFSL--AELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA 467
P PSA S +L AE GQ+ G GGGGG GGG GGGGGGG GGG G GA
Sbjct: 422 PGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGG-GGGGGGGGGGGGGGGGGEAGA 477
Score = 45.4 bits (106), Expect = 3e-04
Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 24/100 (24%)
Query: 401 PPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGN---------- 450
PP P+ RI+ + + + G + G G PG G+
Sbjct: 377 PPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWH 436
Query: 451 --------------GGGGGGGSGGGAGSGGAGGTSSGDDG 476
GGGGGGG GGG G GG GG G+ G
Sbjct: 437 TLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAG 476
>gi|33620755 YEATS domain containing 2 [Homo sapiens]
Length = 1422
Score = 57.0 bits (136), Expect = 1e-07
Identities = 28/59 (47%), Positives = 33/59 (55%), Gaps = 1/59 (1%)
Query: 434 QMNGSVGGGGGAPGGGNGGGGGG-GSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWT 491
Q + GG GA GGG GGGGGG GSGGG +GG GGT+ G I + L +T
Sbjct: 792 QSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYT 850
Score = 47.8 bits (112), Expect = 6e-05
Identities = 23/47 (48%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 430 AELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
A G GGGGG GGG+G GGGG +GGG G+ G G S+ G
Sbjct: 796 AASGGSGAGGGGGGGG-GGGSGSGGGGSTGGGGGTAGGGTQSTAGPG 841
Score = 47.4 bits (111), Expect = 8e-05
Identities = 19/41 (46%), Positives = 23/41 (56%)
Query: 436 NGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
N ++ G A GG GGGGGG GGG G GG++ G G
Sbjct: 788 NANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGG 828
Score = 47.0 bits (110), Expect = 1e-04
Identities = 22/44 (50%), Positives = 24/44 (54%)
Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTS 471
S A G G GGGGG G G+GGGG G GGG GG T+
Sbjct: 795 SAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTA 838
Score = 40.0 bits (92), Expect = 0.013
Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Query: 433 GQMNGSVGGGGGAPGGGN-GGGGGGGSGGGAGSGGAGGTS 471
G G GGG G+ GGG+ GGGGG GG + G GG S
Sbjct: 805 GGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGIS 844
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 56.6 bits (135), Expect = 1e-07
Identities = 24/36 (66%), Positives = 25/36 (69%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAG 468
G GGGGG GGG GG GGGG GGGAG+GGAG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG 277
Score = 52.0 bits (123), Expect = 3e-06
Identities = 21/33 (63%), Positives = 22/33 (66%)
Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
G GG GGG GGGGG G GGG G GAGG +G
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279
Score = 51.6 bits (122), Expect = 4e-06
Identities = 21/33 (63%), Positives = 23/33 (69%)
Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
GGGGG GGG GGGGGG G GAG GAG ++
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAA 283
Score = 47.8 bits (112), Expect = 6e-05
Identities = 19/28 (67%), Positives = 20/28 (71%)
Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
G PG G GGGGGGG GGG+G GG GG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGG 269
Score = 47.8 bits (112), Expect = 6e-05
Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 17/64 (26%)
Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSG-----------------GGAGSGGAGG 469
+S G G GGGGG GGG GGGG G G GG G GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 470 TSSG 473
+S+G
Sbjct: 303 SSAG 306
Score = 32.7 bits (73), Expect = 2.0
Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 8/45 (17%)
Query: 440 GGGGGAPGGGNGGGG--------GGGSGGGAGSGGAGGTSSGDDG 476
GGGGG GG + G G GGG G G GGA S G
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 56.6 bits (135), Expect = 1e-07
Identities = 24/36 (66%), Positives = 25/36 (69%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAG 468
G GGGGG GGG GG GGGG GGGAG+GGAG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG 277
Score = 52.0 bits (123), Expect = 3e-06
Identities = 21/33 (63%), Positives = 22/33 (66%)
Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
G GG GGG GGGGG G GGG G GAGG +G
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279
Score = 51.6 bits (122), Expect = 4e-06
Identities = 21/33 (63%), Positives = 23/33 (69%)
Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
GGGGG GGG GGGGGG G GAG GAG ++
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAA 283
Score = 47.8 bits (112), Expect = 6e-05
Identities = 19/28 (67%), Positives = 20/28 (71%)
Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
G PG G GGGGGGG GGG+G GG GG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGG 269
Score = 47.8 bits (112), Expect = 6e-05
Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 17/64 (26%)
Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSG-----------------GGAGSGGAGG 469
+S G G GGGGG GGG GGGG G G GG G GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 470 TSSG 473
+S+G
Sbjct: 303 SSAG 306
Score = 32.7 bits (73), Expect = 2.0
Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 8/45 (17%)
Query: 440 GGGGGAPGGGNGGGG--------GGGSGGGAGSGGAGGTSSGDDG 476
GGGGG GG + G G GGG G G GGA S G
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 56.6 bits (135), Expect = 1e-07
Identities = 24/36 (66%), Positives = 25/36 (69%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAG 468
G GGGGG GGG GG GGGG GGGAG+GGAG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG 277
Score = 52.0 bits (123), Expect = 3e-06
Identities = 21/33 (63%), Positives = 22/33 (66%)
Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
G GG GGG GGGGG G GGG G GAGG +G
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279
Score = 51.6 bits (122), Expect = 4e-06
Identities = 21/33 (63%), Positives = 23/33 (69%)
Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
GGGGG GGG GGGGGG G GAG GAG ++
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAA 283
Score = 47.8 bits (112), Expect = 6e-05
Identities = 19/28 (67%), Positives = 20/28 (71%)
Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
G PG G GGGGGGG GGG+G GG GG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGG 269
Score = 47.8 bits (112), Expect = 6e-05
Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 17/64 (26%)
Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSG-----------------GGAGSGGAGG 469
+S G G GGGGG GGG GGGG G G GG G GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302
Query: 470 TSSG 473
+S+G
Sbjct: 303 SSAG 306
Score = 32.7 bits (73), Expect = 2.0
Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 8/45 (17%)
Query: 440 GGGGGAPGGGNGGGG--------GGGSGGGAGSGGAGGTSSGDDG 476
GGGGG GG + G G GGG G G GGA S G
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 56.2 bits (134), Expect = 2e-07
Identities = 24/35 (68%), Positives = 25/35 (71%)
Query: 438 SVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
+ GGGGG GGG GGGGGGG GGG GGAGG S
Sbjct: 58 AAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRS 92
Score = 54.3 bits (129), Expect = 6e-07
Identities = 25/41 (60%), Positives = 27/41 (65%)
Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
GGGGG GGG GGGGGG GGGAG G GG S + +M A
Sbjct: 61 GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGA 101
Score = 51.6 bits (122), Expect = 4e-06
Identities = 23/32 (71%), Positives = 24/32 (75%), Gaps = 2/32 (6%)
Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
GGG GGG GGGGGGG GGG G GGAGG + G
Sbjct: 60 GGG--GGGGGGGGGGGGGGGVGGGGAGGGAGG 89
Score = 50.8 bits (120), Expect = 7e-06
Identities = 26/59 (44%), Positives = 31/59 (52%), Gaps = 7/59 (11%)
Query: 437 GSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA-------GGTSSGDDGEMPAMHEIGEEL 488
G GGGGG GGG GG GGGG+GGGAG G + G + P + E+ EL
Sbjct: 62 GGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPEL 120
Score = 48.5 bits (114), Expect = 4e-05
Identities = 21/40 (52%), Positives = 23/40 (57%)
Query: 445 APGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEI 484
A GGG GGGGGGG GGG G G GG G G + E+
Sbjct: 58 AAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVREL 97
Score = 47.8 bits (112), Expect = 6e-05
Identities = 23/49 (46%), Positives = 25/49 (51%)
Query: 431 ELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMP 479
E G+ + S A GGG GGGGGGG GGG G GG G G P
Sbjct: 45 EAGRDDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSP 93
>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
Length = 332
Score = 55.5 bits (132), Expect = 3e-07
Identities = 26/51 (50%), Positives = 28/51 (54%)
Query: 420 ADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGT 470
AD LA G NG+ GGGG G G G G GGG GGAG GG GG+
Sbjct: 20 ADSHHRSILLASSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGS 70
Score = 53.1 bits (126), Expect = 1e-06
Identities = 25/39 (64%), Positives = 25/39 (64%), Gaps = 1/39 (2%)
Query: 438 SVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
S GGG GA GGG G GGG G G GAG GGAGG G G
Sbjct: 31 SSGGGNGA-GGGGGAGGGSGGGNGAGGGGAGGAGGGGGG 68
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 55.5 bits (132), Expect = 3e-07
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 398 IVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAEL----GQMNGSVGGGGGAPGGGNGGG 453
+V P E + + P +A + +++ + G +G GGG G G GGG
Sbjct: 440 LVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGG 499
Query: 454 GGGGSGGGAGSGGAGGTSSGDDG 476
GG G GGG SGG GT+ G G
Sbjct: 500 GGAGGGGGGSSGGGSGTAGGHSG 522
Score = 50.8 bits (120), Expect = 7e-06
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 3/79 (3%)
Query: 401 PPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGG---G 457
PPG P+ + + A + + A ++ GGG GG GG GGG G
Sbjct: 437 PPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSG 496
Query: 458 SGGGAGSGGAGGTSSGDDG 476
GGG GG GG+S G G
Sbjct: 497 GGGGGAGGGGGGSSGGGSG 515
Score = 47.8 bits (112), Expect = 6e-05
Identities = 26/42 (61%), Positives = 28/42 (66%), Gaps = 2/42 (4%)
Query: 433 GQMNGSVGGGG-GAPGGGNGGGGGGGSGGGAG-SGGAGGTSS 472
G GS GG G G GGG GGGGGG SGGG+G +GG G SS
Sbjct: 484 GAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSS 525
Score = 41.6 bits (96), Expect = 0.004
Identities = 18/40 (45%), Positives = 21/40 (52%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
G G G GGG G G GGGG G G G G +G +S+
Sbjct: 487 GGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSN 526
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 55.5 bits (132), Expect = 3e-07
Identities = 31/71 (43%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 407 PNIRIEPPKKVPSADKRKSVFS-LAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSG 465
PN PP ++P KR+ G G G GGG GGG GG GGGG G G G G
Sbjct: 312 PNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371
Query: 466 GAGGTSSGDDG 476
G GG G G
Sbjct: 372 GGGGWGGGGGG 382
Score = 46.6 bits (109), Expect = 1e-04
Identities = 25/49 (51%), Positives = 25/49 (51%), Gaps = 7/49 (14%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGG-------GGSGGGAGSGGAGGTSSGD 474
G G GGGGG GGG GG GG GG GG G GG GG GD
Sbjct: 364 GGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGD 412
Score = 42.0 bits (97), Expect = 0.003
Identities = 19/33 (57%), Positives = 19/33 (57%)
Query: 437 GSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
G GG GG G G G GGG GGG G GG GG
Sbjct: 397 GGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
Score = 40.0 bits (92), Expect = 0.013
Identities = 21/42 (50%), Positives = 21/42 (50%), Gaps = 7/42 (16%)
Query: 434 QMNGSVGGGGGAPGGGNGGG-------GGGGSGGGAGSGGAG 468
Q G GG GG G G GG GGGG GGG G GG G
Sbjct: 388 QGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
Score = 39.7 bits (91), Expect = 0.016
Identities = 18/29 (62%), Positives = 18/29 (62%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGG 461
G G G G G P GG GGGGGGG GGG
Sbjct: 400 GGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 55.1 bits (131), Expect = 4e-07
Identities = 26/44 (59%), Positives = 29/44 (65%), Gaps = 3/44 (6%)
Query: 433 GQMNGSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
G G GGG GG+ GGG+GGG GG SGGG G G +GG SSG
Sbjct: 467 GSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510
Score = 54.7 bits (130), Expect = 5e-07
Identities = 28/48 (58%), Positives = 31/48 (64%), Gaps = 3/48 (6%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGG---GGGSGGGAGSGGAGGTSSGDDGE 477
G GS GGGGG GGG+ GGG GGG GGG+ SGG +SSG GE
Sbjct: 529 GYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGE 576
Score = 51.6 bits (122), Expect = 4e-06
Identities = 26/46 (56%), Positives = 29/46 (63%), Gaps = 2/46 (4%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGSGGAGGTSSGDDG 476
G G G GG GGG+ GGG GGG GGG+ SGG GG+SSG G
Sbjct: 486 GHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYG 531
Score = 51.2 bits (121), Expect = 5e-06
Identities = 25/40 (62%), Positives = 29/40 (72%), Gaps = 2/40 (5%)
Query: 436 NGSVGGGGGAPGGGNGGGGGGGSGGGAGSGG--AGGTSSG 473
+ S G GGG+ GGG GG GGG SGGG+ SGG GG+SSG
Sbjct: 525 SSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG 564
Score = 50.8 bits (120), Expect = 7e-06
Identities = 27/43 (62%), Positives = 29/43 (67%), Gaps = 3/43 (6%)
Query: 437 GSVGGG-GGAPGGGNGGGGGGGSGGGAGSGG--AGGTSSGDDG 476
GS GGG GG GG +GGG GGGS GG SGG GG+SSG G
Sbjct: 481 GSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHG 523
Score = 50.4 bits (119), Expect = 9e-06
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 433 GQMNGSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G G GGG GG+ GGG GGG G GG+ SGG GG SSG G
Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGG 539
Score = 48.9 bits (115), Expect = 3e-05
Identities = 27/50 (54%), Positives = 30/50 (60%), Gaps = 1/50 (2%)
Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGG-GGGGSGGGAGSGGAGGTSSGDDG 476
SL E +G G GGG+ GGG GGG GGGS GG GG GG+S G G
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYG 500
Score = 48.9 bits (115), Expect = 3e-05
Identities = 22/39 (56%), Positives = 24/39 (61%)
Query: 438 SVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
S GG GG+ GG GGG GG GGG G G +GG SS G
Sbjct: 518 SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGG 556
Score = 48.1 bits (113), Expect = 5e-05
Identities = 22/42 (52%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Query: 437 GSVGGG--GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
GS GGG GG+ GG+GG GG GGG+ GG GG G G
Sbjct: 507 GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSG 548
Score = 46.6 bits (109), Expect = 1e-04
Identities = 24/42 (57%), Positives = 27/42 (64%), Gaps = 3/42 (7%)
Query: 437 GSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDD 475
GS GGG GG+ GGG GGGG G G G G GG GG SG++
Sbjct: 105 GSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNE 146
Score = 45.8 bits (107), Expect = 2e-04
Identities = 27/45 (60%), Positives = 29/45 (64%), Gaps = 5/45 (11%)
Query: 437 GSVGG--GGGAPGGGN-GGG--GGGGSGGGAGSGGAGGTSSGDDG 476
GS GG GGG+ GGG+ GGG GGGG GGG GG GG GD G
Sbjct: 96 GSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGG 140
Score = 44.7 bits (104), Expect = 5e-04
Identities = 20/46 (43%), Positives = 25/46 (54%)
Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGE 486
GGG + GGG G GGG GG + GG GG SS + + +GE
Sbjct: 531 GGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGE 576
Score = 43.9 bits (102), Expect = 9e-04
Identities = 23/47 (48%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 433 GQMNGSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G GS GGG GG GG + GG GG S GG G G +GG G G
Sbjct: 498 GYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGG 544
Score = 40.8 bits (94), Expect = 0.007
Identities = 21/43 (48%), Positives = 23/43 (53%), Gaps = 2/43 (4%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA--GGTSSG 473
G GS GG G G GGG G GGG GG+ GG+SSG
Sbjct: 512 GYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSG 554
Score = 38.5 bits (88), Expect = 0.037
Identities = 25/53 (47%), Positives = 28/53 (52%), Gaps = 9/53 (16%)
Query: 428 SLAELGQMNGSVGGG---GGAPGG----GNGGGG--GGGSGGGAGSGGAGGTS 471
S + GS+GGG GG GG G+ GGG GG SGG G GG GG S
Sbjct: 32 SSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGS 84
Score = 37.4 bits (85), Expect = 0.082
Identities = 17/40 (42%), Positives = 20/40 (50%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
G G GGG + GGG GGG G + SG G +SS
Sbjct: 540 GGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSS 579
Score = 36.6 bits (83), Expect = 0.14
Identities = 22/42 (52%), Positives = 22/42 (52%), Gaps = 12/42 (28%)
Query: 440 GGGGGAPGGGNGGGGG----------GGSGGGAGSGGAGGTS 471
GGGGG GGG GGGGG G GGG SGG G S
Sbjct: 17 GGGGG--GGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGS 56
Score = 36.2 bits (82), Expect = 0.18
Identities = 22/44 (50%), Positives = 24/44 (54%), Gaps = 4/44 (9%)
Query: 437 GSVGGG--GGAPGG--GNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
GS GGG GG+ GG G GG GGG G GS GG+ G G
Sbjct: 60 GSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFG 103
Score = 34.3 bits (77), Expect = 0.69
Identities = 25/57 (43%), Positives = 26/57 (45%), Gaps = 20/57 (35%)
Query: 440 GGGGGAPGGGNG-------------GGG---GGGSGG----GAGSGGAGGTSSGDDG 476
GGGGG GGG G GGG GG SGG G+ GG G SSG G
Sbjct: 19 GGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75
Score = 33.9 bits (76), Expect = 0.90
Identities = 23/61 (37%), Positives = 26/61 (42%), Gaps = 20/61 (32%)
Query: 436 NGSVGGGGGAPGGGN-------------GGG-------GGGGSGGGAGSGGAGGTSSGDD 475
+G GGGGG GGG GGG GG S G +G G GG+S G
Sbjct: 16 SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75
Query: 476 G 476
G
Sbjct: 76 G 76
Score = 33.9 bits (76), Expect = 0.90
Identities = 24/57 (42%), Positives = 24/57 (42%), Gaps = 13/57 (22%)
Query: 433 GQMNGSVGGGGGAPGGGNG-----------GGGGGGS--GGGAGSGGAGGTSSGDDG 476
G GS GG GG G G G GG GGS GG G G GG S G G
Sbjct: 65 GCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGG 121
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 54.3 bits (129), Expect = 6e-07
Identities = 27/68 (39%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Query: 407 PNIRIEPPKKVPS--ADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGS 464
P+ + P KKV S A+ S + ++ G+ VGG GG GG GGGG +GGG G
Sbjct: 124 PDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGG 183
Query: 465 GGAGGTSS 472
GG +S
Sbjct: 184 ASGGGANS 191
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 53.9 bits (128), Expect = 8e-07
Identities = 25/44 (56%), Positives = 26/44 (59%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
G G G GGG G G GGGGGGG GGG G GG G S G+ G
Sbjct: 28 GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRG 71
Score = 45.1 bits (105), Expect = 4e-04
Identities = 22/41 (53%), Positives = 23/41 (56%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
G+ G G G G GGG GGGGGG GGG SGG G G
Sbjct: 35 GRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRG 75
Score = 43.9 bits (102), Expect = 9e-04
Identities = 25/51 (49%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Query: 437 GSVGGGGGAPGGGNGGGGGG---GSGGGAGSGGAGGTSSGDDGEM-PAMHE 483
G GGGGG GGG G GGGG G G G GG G SG + + P HE
Sbjct: 44 GRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHE 94
Score = 41.2 bits (95), Expect = 0.006
Identities = 22/45 (48%), Positives = 22/45 (48%), Gaps = 5/45 (11%)
Query: 437 GSVGGGGGAPGGGNGGGGGG-----GSGGGAGSGGAGGTSSGDDG 476
G GG GG G G G G GG G GGG G GG GG G G
Sbjct: 19 GDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63
Score = 37.4 bits (85), Expect = 0.082
Identities = 18/37 (48%), Positives = 18/37 (48%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
G G G GG G G GGG G GG G GG GG
Sbjct: 19 GDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG 55
Score = 35.4 bits (80), Expect = 0.31
Identities = 21/45 (46%), Positives = 21/45 (46%), Gaps = 5/45 (11%)
Query: 437 GSVGGGGG-APGGGNGGGGGGGSGGGAGSG----GAGGTSSGDDG 476
G GG GG GG GG GG G G G G G G GG G G
Sbjct: 10 GGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGG 54
Score = 34.3 bits (77), Expect = 0.69
Identities = 17/34 (50%), Positives = 17/34 (50%)
Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
GGG G GG GG GG GG G G GG G
Sbjct: 9 GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRG 42
Score = 32.0 bits (71), Expect = 3.4
Identities = 16/34 (47%), Positives = 16/34 (47%)
Query: 443 GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
GG GG G G GG GG G GG G G G
Sbjct: 9 GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRG 42
>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
isoform b [Homo sapiens]
Length = 373
Score = 52.8 bits (125), Expect = 2e-06
Identities = 25/41 (60%), Positives = 26/41 (63%), Gaps = 4/41 (9%)
Query: 433 GQMNGSVGGGGGAPGGG----NGGGGGGGSGGGAGSGGAGG 469
G S GG GGA GGG GGGGGGG GGG G+ GAGG
Sbjct: 204 GSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGG 244
Score = 52.8 bits (125), Expect = 2e-06
Identities = 23/38 (60%), Positives = 26/38 (68%)
Query: 430 AELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA 467
A G G+ GGG + GGG GGGGGGG GG AG+GGA
Sbjct: 208 ASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGA 245
Score = 44.3 bits (103), Expect = 7e-04
Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 437 GSVGGGGGAPGGGNGGGGGG-GSGGGAGSGGAGGTSSGDDGEMPAMH 482
G+ G + GG G GGGG S GG G GG GG G G A+H
Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALH 247
Score = 35.4 bits (80), Expect = 0.31
Identities = 20/64 (31%), Positives = 24/64 (37%), Gaps = 11/64 (17%)
Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGS-----------GGGAGSGGAGGTSSGDDGEMPAM 481
G + G GA G GG G GGG G GG GG ++G G +
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPH 249
Query: 482 HEIG 485
H G
Sbjct: 250 HAAG 253
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.140 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,732,029
Number of Sequences: 37866
Number of extensions: 2363618
Number of successful extensions: 38331
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 481
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 18189
Number of HSP's gapped (non-prelim): 8585
length of query: 1137
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1024
effective length of database: 13,968,660
effective search space: 14303907840
effective search space used: 14303907840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.