Guide to the Human Genome
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Search of human proteins with 125987596

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
sapiens]
         (1137 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa...  2305   0.0  
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap...  2263   0.0  
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans...  1303   0.0  
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo...  1296   0.0  
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans...  1295   0.0  
gi|155722998 solute carrier family 4, sodium bicarbonate transpo...   974   0.0  
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp...   966   0.0  
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp...   964   0.0  
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans...   842   0.0  
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans...   821   0.0  
gi|157671951 solute carrier family 4, anion exchanger, member 3 ...   598   e-170
gi|157671953 solute carrier family 4, anion exchanger, member 3 ...   598   e-170
gi|156071474 solute carrier family 4, anion exchanger, member 2 ...   593   e-169
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H...   525   e-148
gi|14042960 solute carrier family 4 member 11 [Homo sapiens]          212   2e-54
gi|55956899 keratin 9 [Homo sapiens]                                   60   1e-08
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    59   3e-08
gi|21322252 androgen receptor isoform 1 [Homo sapiens]                 57   8e-08
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   57   1e-07
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    57   1e-07
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    57   1e-07
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    57   1e-07
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]          56   2e-07
gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]               55   3e-07
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]     55   3e-07
gi|109452587 family with sequence similarity 98, member B isofor...    55   3e-07
gi|195972866 keratin 10 [Homo sapiens]                                 55   4e-07
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]         54   6e-07
gi|12056465 fibrillarin [Homo sapiens]                                 54   8e-07
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...    53   2e-06

>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
            sapiens]
          Length = 1137

 Score = 2305 bits (5973), Expect = 0.0
 Identities = 1137/1137 (100%), Positives = 1137/1137 (100%)

Query: 1    MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60
            MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG
Sbjct: 1    MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60

Query: 61   LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120
            LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL
Sbjct: 61   LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120

Query: 121  QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180
            QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS
Sbjct: 121  QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180

Query: 181  GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240
            GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR
Sbjct: 181  GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240

Query: 241  SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300
            SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK
Sbjct: 241  SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300

Query: 301  DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360
            DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI
Sbjct: 301  DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360

Query: 361  GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420
            GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA
Sbjct: 361  GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420

Query: 421  DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
            DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA
Sbjct: 421  DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480

Query: 481  MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540
            MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG
Sbjct: 481  MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540

Query: 541  GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600
            GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL
Sbjct: 541  GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600

Query: 601  DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660
            DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF
Sbjct: 601  DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660

Query: 661  KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720
            KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL
Sbjct: 661  KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720

Query: 721  SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780
            SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD
Sbjct: 721  SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780

Query: 781  FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840
            FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL
Sbjct: 781  FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840

Query: 841  LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900
            LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI
Sbjct: 841  LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900

Query: 901  AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960
            AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF
Sbjct: 901  AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960

Query: 961  LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1020
            LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF
Sbjct: 961  LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1020

Query: 1021 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1080
            TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE
Sbjct: 1021 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1080

Query: 1081 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1137
            TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL
Sbjct: 1081 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1137


>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
          Length = 1121

 Score = 2263 bits (5863), Expect = 0.0
 Identities = 1121/1137 (98%), Positives = 1121/1137 (98%), Gaps = 16/1137 (1%)

Query: 1    MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60
            MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG
Sbjct: 1    MKVKEEKAGVGKLDHTNHRRRFPDQKECPPIHIGLPVPTYPQRKTDQKGHLSGLQKVHWG 60

Query: 61   LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120
            LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL
Sbjct: 61   LRPDQPQQELTGPGSGASSQDSSMDLISRTRSPAAEQLQDILGEEDEAPNPTLFTEMDTL 120

Query: 121  QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180
            QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS
Sbjct: 121  QHDGDQMEWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDS 180

Query: 181  GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240
            GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR
Sbjct: 181  GSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNR 240

Query: 241  SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300
            SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK
Sbjct: 241  SPARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPK 300

Query: 301  DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360
            DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI
Sbjct: 301  DSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEI 360

Query: 361  GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420
            GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA
Sbjct: 361  GRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSA 420

Query: 421  DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
            DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA
Sbjct: 421  DKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480

Query: 481  MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540
            MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG
Sbjct: 481  MHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFG 540

Query: 541  GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600
            GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL
Sbjct: 541  GLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGL 600

Query: 601  DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660
            DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF
Sbjct: 601  DYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF 660

Query: 661  KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720
            KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL
Sbjct: 661  KYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLL 720

Query: 721  SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780
            SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD
Sbjct: 721  SKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVAD 780

Query: 781  FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840
            FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL
Sbjct: 781  FSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPAL 840

Query: 841  LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900
            LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI
Sbjct: 841  LVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISI 900

Query: 901  AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960
            AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF
Sbjct: 901  AHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVF 960

Query: 961  LYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1020
            LYMGVASLNGIQ                FWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF
Sbjct: 961  LYMGVASLNGIQ----------------FWERCKLFLMPAKHQPDHAFLRHVPLRRIHLF 1004

Query: 1021 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1080
            TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE
Sbjct: 1005 TLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKE 1064

Query: 1081 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1137
            TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL
Sbjct: 1065 TDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMESVQSDPQNGIHCIARKRSSSWSYSL 1121


>gi|148596928 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 1 [Homo sapiens]
          Length = 1079

 Score = 1303 bits (3371), Expect = 0.0
 Identities = 671/1101 (60%), Positives = 825/1101 (74%), Gaps = 86/1101 (7%)

Query: 31   IHIGLPVPTYPQRKTDQK---GHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLI 87
            I+IG+ VP   +R+   K   GH    +K       ++  +  +      ++ +SS  ++
Sbjct: 29   IYIGVHVPKSYRRRRRHKRKTGHKEKKEK-------ERISENYSDKSDIENADESSSSIL 81

Query: 88   SRTRSPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEG 145
                SPAAE+++ ILGEED++P P  LFTE+D L   DG +MEWKE+ARWIKFEEKVE+G
Sbjct: 82   KPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQG 141

Query: 146  GERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELR 205
            GERWSKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+
Sbjct: 142  GERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELK 201

Query: 206  ERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSA 265
            ++V+Y LLR+HRHQTKK   RSLADIGK+VS+ +R         P++ H           
Sbjct: 202  DKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR---------- 251

Query: 266  NYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRL 325
                  +  S S+NDIS  P  DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL
Sbjct: 252  ------NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRL 305

Query: 326  IQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNRED 385
             Q+ MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R D
Sbjct: 306  QQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHD 365

Query: 386  LIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGA 445
            LIAGIDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S  E  QMNG     GG 
Sbjct: 366  LIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH 425

Query: 446  PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRK 505
             GGG+G                                  EEL  TGRF GGL  DIKRK
Sbjct: 426  GGGGHGDC--------------------------------EELQRTGRFCGGLIKDIKRK 453

Query: 506  LPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGS 565
             P+F SDFYD  +IQ++SAILFIYL  +TNAITFGGLLGDATDN QGV+ESFLGTA++G+
Sbjct: 454  APFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGA 513

Query: 566  LFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDA 625
            +FCLF+GQPL ILSSTGP+L+FE+LLF+FSK N  DY+EFRLWIGL SA  CLILVATDA
Sbjct: 514  IFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDA 573

Query: 626  SFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPD 685
            SF+++Y TRFTEEGFS+LISFIFIYDA KKMI    YYPIN +FK  + T + C CV PD
Sbjct: 574  SFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPD 633

Query: 686  TVNTTVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDL 743
              N ++ N +  LAP+     S  ++ + T  DW+ LSKKEC  YGG L+GN+C F+PD+
Sbjct: 634  PANISISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692

Query: 744  ALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPK 803
             LMSFILF GTY+ ++ LKKFK S YFPT  R L++DF+I+ SIL+FC IDA  G++TPK
Sbjct: 693  TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPK 752

Query: 804  LHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENK 863
            L VPS  KPT P+RGWFV PFG+NPWWV  A+ +PALLVTILIFMDQQITAVIVNRKE+K
Sbjct: 753  LIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHK 812

Query: 864  LKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLG 923
            LKK AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLG
Sbjct: 813  LKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLG 872

Query: 924  VREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQ 983
            VREQRVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q           
Sbjct: 873  VREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ----------- 921

Query: 984  KKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIF 1043
                 F +R KL LMP KHQPD  +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIF
Sbjct: 922  -----FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIF 976

Query: 1044 PVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQF 1101
            PVMIL L+ VR+ +D++FSQHDL+++D+++PEK+  KKE +KK+K+KKG+ +  +++   
Sbjct: 977  PVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDC 1036

Query: 1102 P----PPSVIKIPMESVQSDP 1118
            P     PS IKIPM+ ++  P
Sbjct: 1037 PYSEKVPS-IKIPMDIMEQQP 1056


>gi|4507025 solute carrier family 4, sodium bicarbonate cotransporter,
            member 4 isoform 2 [Homo sapiens]
          Length = 1035

 Score = 1296 bits (3354), Expect = 0.0
 Identities = 659/1037 (63%), Positives = 799/1037 (77%), Gaps = 76/1037 (7%)

Query: 92   SPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEGGERW 149
            SPAAE+++ ILGEED++P P  LFTE+D L   DG +MEWKE+ARWIKFEEKVE+GGERW
Sbjct: 42   SPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERW 101

Query: 150  SKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVS 209
            SKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+++V+
Sbjct: 102  SKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVT 161

Query: 210  YVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGR 269
            Y LLR+HRHQTKK   RSLADIGK+VS+ +R         P++ H               
Sbjct: 162  YTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR-------------- 207

Query: 270  LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329
              +  S S+NDIS  P  DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL Q+ 
Sbjct: 208  --NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAV 265

Query: 330  MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389
            MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R DLIAG
Sbjct: 266  MLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAG 325

Query: 390  IDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGG 449
            IDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S  E  QMNG     GG  GGG
Sbjct: 326  IDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGG 385

Query: 450  NGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWF 509
            +G                                  EEL  TGRF GGL  DIKRK P+F
Sbjct: 386  HGDC--------------------------------EELQRTGRFCGGLIKDIKRKAPFF 413

Query: 510  PSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCL 569
             SDFYD  +IQ++SAILFIYL  +TNAITFGGLLGDATDN QGV+ESFLGTA++G++FCL
Sbjct: 414  ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 473

Query: 570  FSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFII 629
            F+GQPL ILSSTGP+L+FE+LLF+FSK N  DY+EFRLWIGL SA  CLILVATDASF++
Sbjct: 474  FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 533

Query: 630  KYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNT 689
            +Y TRFTEEGFS+LISFIFIYDA KKMI    YYPIN +FK  + T + C CV PD  N 
Sbjct: 534  QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 593

Query: 690  TVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMS 747
            ++ N +  LAP+     S  ++ + T  DW+ LSKKEC  YGG L+GN+C F+PD+ LMS
Sbjct: 594  SISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMS 652

Query: 748  FILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVP 807
            FILF GTY+ ++ LKKFK S YFPT  R L++DF+I+ SIL+FC IDA  G++TPKL VP
Sbjct: 653  FILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVP 712

Query: 808  SVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKA 867
            S  KPT P+RGWFV PFG+NPWWV  A+ +PALLVTILIFMDQQITAVIVNRKE+KLKK 
Sbjct: 713  SEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKG 772

Query: 868  AGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQ 927
            AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLGVREQ
Sbjct: 773  AGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQ 832

Query: 928  RVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLT 987
            RVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q               
Sbjct: 833  RVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ--------------- 877

Query: 988  PFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMI 1047
             F +R KL LMP KHQPD  +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIFPVMI
Sbjct: 878  -FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMI 936

Query: 1048 LGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQFP--- 1102
            L L+ VR+ +D++FSQHDL+++D+++PEK+  KKE +KK+K+KKG+ +  +++   P   
Sbjct: 937  LALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSE 996

Query: 1103 -PPSVIKIPMESVQSDP 1118
              PS IKIPM+ ++  P
Sbjct: 997  KVPS-IKIPMDIMEQQP 1012


>gi|197927160 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 3 [Homo sapiens]
          Length = 1094

 Score = 1295 bits (3352), Expect = 0.0
 Identities = 665/1078 (61%), Positives = 813/1078 (75%), Gaps = 82/1078 (7%)

Query: 31   IHIGLPVPTYPQRKTDQK---GHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLI 87
            I+IG+ VP   +R+   K   GH    +K       ++  +  +      ++ +SS  ++
Sbjct: 29   IYIGVHVPKSYRRRRRHKRKTGHKEKKEK-------ERISENYSDKSDIENADESSSSIL 81

Query: 88   SRTRSPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEG 145
                SPAAE+++ ILGEED++P P  LFTE+D L   DG +MEWKE+ARWIKFEEKVE+G
Sbjct: 82   KPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQG 141

Query: 146  GERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELR 205
            GERWSKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+
Sbjct: 142  GERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELK 201

Query: 206  ERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSA 265
            ++V+Y LLR+HRHQTKK   RSLADIGK+VS+ +R         P++ H           
Sbjct: 202  DKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR---------- 251

Query: 266  NYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRL 325
                  +  S S+NDIS  P  DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL
Sbjct: 252  ------NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRL 305

Query: 326  IQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNRED 385
             Q+ MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R D
Sbjct: 306  QQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHD 365

Query: 386  LIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGA 445
            LIAGIDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S  E  QMNG     GG 
Sbjct: 366  LIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH 425

Query: 446  PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRK 505
             GGG+G                                  EEL  TGRF GGL  DIKRK
Sbjct: 426  GGGGHGDC--------------------------------EELQRTGRFCGGLIKDIKRK 453

Query: 506  LPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGS 565
             P+F SDFYD  +IQ++SAILFIYL  +TNAITFGGLLGDATDN QGV+ESFLGTA++G+
Sbjct: 454  APFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGA 513

Query: 566  LFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDA 625
            +FCLF+GQPL ILSSTGP+L+FE+LLF+FSK N  DY+EFRLWIGL SA  CLILVATDA
Sbjct: 514  IFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDA 573

Query: 626  SFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPD 685
            SF+++Y TRFTEEGFS+LISFIFIYDA KKMI    YYPIN +FK  + T + C CV PD
Sbjct: 574  SFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPD 633

Query: 686  TVNTTVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDL 743
              N ++ N +  LAP+     S  ++ + T  DW+ LSKKEC  YGG L+GN+C F+PD+
Sbjct: 634  PANISISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 692

Query: 744  ALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPK 803
             LMSFILF GTY+ ++ LKKFK S YFPT  R L++DF+I+ SIL+FC IDA  G++TPK
Sbjct: 693  TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPK 752

Query: 804  LHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENK 863
            L VPS  KPT P+RGWFV PFG+NPWWV  A+ +PALLVTILIFMDQQITAVIVNRKE+K
Sbjct: 753  LIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHK 812

Query: 864  LKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLG 923
            LKK AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLG
Sbjct: 813  LKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLG 872

Query: 924  VREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQ 983
            VREQRVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q           
Sbjct: 873  VREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ----------- 921

Query: 984  KKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIF 1043
                 F +R KL LMP KHQPD  +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIF
Sbjct: 922  -----FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIF 976

Query: 1044 PVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGA-HEDCDEE 1098
            PVMIL L+ VR+ +D++FSQHDL+++D+++PEK+  KKE +KK+K+KKG+   D D+E
Sbjct: 977  PVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDE 1034


>gi|155722998 solute carrier family 4, sodium bicarbonate
            transporter-like, member 10 [Homo sapiens]
          Length = 1088

 Score =  974 bits (2517), Expect = 0.0
 Identities = 521/1105 (47%), Positives = 705/1105 (63%), Gaps = 115/1105 (10%)

Query: 44   KTDQKGHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMD--LISRTRSPA----AEQ 97
            K D +GH +    VH  L   +  +     G     +D   D  L     SP+    +++
Sbjct: 39   KEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQR 98

Query: 98   LQDILGEEDEAPNPT---LFTEMDTL-QHDGDQMEWKESARWIKFEEKVEEGGERWSKPH 153
            +Q ILG ED+        LFTE+D +   +G+  EW+E+ARW+KFEE VE+GGERWSKP+
Sbjct: 99   VQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPY 158

Query: 154  VSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLL 213
            V+TLSLHSLFELR+C+  GTVLLD+ + +L +I D V+++Q+  G L  ++R RV   L+
Sbjct: 159  VATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALM 218

Query: 214  RRHRHQTKK------PIHRSLADIGKSVSTTNRSPAR-----SPGAGPSLHHSTEDLRMR 262
            ++H HQ +K      PI RS ADIGK  S  N          SP + P+   +  D+   
Sbjct: 219  KQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRE 278

Query: 263  QSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAF 322
             S                   T +  +    FMKKIP  +EASN+LVGE++FLD+  +AF
Sbjct: 279  NS-------------------TVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTVVAF 319

Query: 323  VRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARN 382
            VRL  + +L G+ EVP+PTRFLFILLGP G+ + Y+EIGR+IATLM D++F DVAYKA++
Sbjct: 320  VRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKD 379

Query: 383  REDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGG 442
            R DL++GIDEFLD+V VLPPGEWDP+IRIEPPK VPS +KRK           NG+   G
Sbjct: 380  RNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIP------AVPNGTAAHG 433

Query: 443  GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDI 502
               P GG+ G                                  EL  TGR FGGL LDI
Sbjct: 434  EAEPHGGHSG---------------------------------PELQRTGRIFGGLILDI 460

Query: 503  KRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAM 562
            KRK P+F SDF D F +Q +++ LF+Y  C++  ITFGGLLG+AT+     +ES  G +M
Sbjct: 461  KRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASM 520

Query: 563  AGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVA 622
             G  + LF GQPL IL STGP+L+FEK+LF F K  GL Y+  R  IGL +A  C+ILVA
Sbjct: 521  TGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVA 580

Query: 623  TDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECV 682
            TDAS ++ YITRFTEE F++LI  IFIY+A++K+    + YPINM      +T Y C CV
Sbjct: 581  TDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCV 640

Query: 683  APDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSC----K 738
             P   +    N +     ++N S  +++      W  L+  EC S  G  +G +C     
Sbjct: 641  EPHNPS----NGTLKEWRESNISASDII------WENLTVSECKSLHGEYVGRACGHDHP 690

Query: 739  FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFG 798
            ++PD+   S ILFF T +++ TLK+FK SRYFPTKVR++V+DF++  +IL    ID   G
Sbjct: 691  YVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIG 750

Query: 799  LETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVN 858
            + +PKL VPSV KPTR DRGWFV P G NPWW   A+I+PALL TILIFMDQQITAVI+N
Sbjct: 751  IPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIIN 810

Query: 859  RKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQ 918
            RKE+KLKK  GYHLDL  V +++ +CS MGLPW+VAATV+SI H++SLK+E+E SAPGEQ
Sbjct: 811  RKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ 870

Query: 919  PQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGS 978
            P+FLG+REQRVTG+++FIL G SVF+  ILK IP+PVLYGVFLYMG +SL GIQ      
Sbjct: 871  PKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQ------ 924

Query: 979  EFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTV 1038
                      F++R KLF MPAKHQPD  +LRHVPLR++HLFT++Q+ CL +LWI+K + 
Sbjct: 925  ----------FFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSR 974

Query: 1039 AAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKETDKKRKRKKGAHEDCDEE 1098
            AAI+FP+M+L L+ VR+L+D +F++ +L+W+D+++PE +KK+ +   K ++ +    ++E
Sbjct: 975  AAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDE 1034

Query: 1099 PQFPPPSVIKIPMESVQSDPQNGIH 1123
                    +++P+E    D  + I+
Sbjct: 1035 ------GTVQLPLEGHYRDDPSVIN 1053


>gi|90403614 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform a [Homo sapiens]
          Length = 1093

 Score =  966 bits (2498), Expect = 0.0
 Identities = 514/1068 (48%), Positives = 695/1068 (65%), Gaps = 100/1068 (9%)

Query: 72   GPGSGASSQDSSMDLISRTRSPAAEQLQDILG-EEDEAPNP-TLFTEMDTL-QHDGDQME 128
            G G GAS  +  ++ ++      ++++Q ILG EEDE   P  LFTE+D +   +G+  E
Sbjct: 75   GRGKGASQGEEGLEALAH--DTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAE 132

Query: 129  WKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIID 188
            WKE+ARW+KFEE VE+GGERWSKP+V+TLSLHSLFELR+CL  GTVLLD+ + S+ +I D
Sbjct: 133  WKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISD 192

Query: 189  DVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSP 242
             ++++Q     L   +R +V   LL++H HQ +K      PI RS A++GK  S  +   
Sbjct: 193  LILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMD 252

Query: 243  ARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDS 302
                   P    +T +L ++   N    C      ++ + L          FMKKIP  +
Sbjct: 253  KHGQTVSPQSVPTT-NLEVKNGVN----CEHSPVDLSKVDL---------HFMKKIPTGA 298

Query: 303  EASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGR 362
            EASNVLVGEVD LD+P +AFVRL  + +L G+TEVP+PTRFLFILLGP G+ + Y+EIGR
Sbjct: 299  EASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGR 358

Query: 363  AIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADK 422
            ++AT+M D++F DVAYKA+ R+DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK VPS +K
Sbjct: 359  SMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEK 418

Query: 423  RKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482
            RK        G  NG+V      P GG+ G                              
Sbjct: 419  RKMP------GVPNGNVCHIEQEPHGGHSG------------------------------ 442

Query: 483  EIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGL 542
                EL  TGR FGGL LDIKRK PW+ SD+ D   +Q +++ LF+Y  C++  ITFGGL
Sbjct: 443  ---PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGL 499

Query: 543  LGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDY 602
            LG+AT+     +ES  G +M G  + LF+GQ L IL STGP+L+FEK+LF F K   L Y
Sbjct: 500  LGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSY 559

Query: 603  MEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKY 662
            +  R  IGL +A  C++LVATDAS ++ YITRFTEE F++LI  IFIY+AI+K+I   + 
Sbjct: 560  LSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAET 619

Query: 663  YPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSK 722
            YPI+M  + + ++ Y C C  P+  N    N +     D N      +    + W+ L+ 
Sbjct: 620  YPIHMHSQLDHLSLYYCRCTLPENPN----NHTLQYWKDHN------IVTAEVHWANLTV 669

Query: 723  KECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALV 778
             EC    G  +G++C     + PD+   S ILFF T+ ++ TLK FK SRYFPT+VR++V
Sbjct: 670  SECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMV 729

Query: 779  ADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILP 838
            +DF++  +I     ID   G+ +PKL VPSV KPTR DRGW + P G NPWW   A+I+P
Sbjct: 730  SDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIP 789

Query: 839  ALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVI 898
            ALL TILIFMDQQITAVI+NRKE+KLKK  GYHLDL  V I++ +CS MGLPW+VAATV+
Sbjct: 790  ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849

Query: 899  SIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYG 958
            SI H++SLK+E+E SAPGEQP+FLG+REQRVTG+++F+L G SVF+  ILK IP+PVLYG
Sbjct: 850  SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909

Query: 959  VFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIH 1018
            VFLYMGV+SL GIQ                F++R KLF MPAKHQPD  +LRHVPLR++H
Sbjct: 910  VFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVH 953

Query: 1019 LFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEK 1078
            LFTL+Q+ CL +LW++K++ AAI+FP+M+L L+ VR+++D  FS+ +L+W+D+++PE +K
Sbjct: 954  LFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKK 1013

Query: 1079 KETDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMES--VQSDPQNGIHC 1124
            K+ D  +K+ K    + +E  +       K P+ES  + S P   I C
Sbjct: 1014 KKLDDAKKKAK----EEEEAEKMLEIGGDKFPLESRKLLSSPGKNISC 1057


>gi|90568034 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform b [Homo sapiens]
          Length = 1044

 Score =  964 bits (2492), Expect = 0.0
 Identities = 505/1031 (48%), Positives = 681/1031 (66%), Gaps = 94/1031 (9%)

Query: 72   GPGSGASSQDSSMDLISRTRSPAAEQLQDILG-EEDEAPNP-TLFTEMDTL-QHDGDQME 128
            G G GAS  +  ++ ++      ++++Q ILG EEDE   P  LFTE+D +   +G+  E
Sbjct: 75   GRGKGASQGEEGLEALAH--DTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAE 132

Query: 129  WKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIID 188
            WKE+ARW+KFEE VE+GGERWSKP+V+TLSLHSLFELR+CL  GTVLLD+ + S+ +I D
Sbjct: 133  WKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISD 192

Query: 189  DVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSP 242
             ++++Q     L   +R +V   LL++H HQ +K      PI RS A++GK  S  +   
Sbjct: 193  LILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMD 252

Query: 243  ARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDS 302
                   P    +T +L ++   N    C      ++ + L          FMKKIP  +
Sbjct: 253  KHGQTVSPQSVPTT-NLEVKNGVN----CEHSPVDLSKVDL---------HFMKKIPTGA 298

Query: 303  EASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGR 362
            EASNVLVGEVD LD+P +AFVRL  + +L G+TEVP+PTRFLFILLGP G+ + Y+EIGR
Sbjct: 299  EASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGR 358

Query: 363  AIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADK 422
            ++AT+M D++F DVAYKA+ R+DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK VPS +K
Sbjct: 359  SMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEK 418

Query: 423  RKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482
            RK        G  NG+V      P GG+ G                              
Sbjct: 419  RKMP------GVPNGNVCHIEQEPHGGHSG------------------------------ 442

Query: 483  EIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGL 542
                EL  TGR FGGL LDIKRK PW+ SD+ D   +Q +++ LF+Y  C++  ITFGGL
Sbjct: 443  ---PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGL 499

Query: 543  LGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDY 602
            LG+AT+     +ES  G +M G  + LF+GQ L IL STGP+L+FEK+LF F K   L Y
Sbjct: 500  LGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSY 559

Query: 603  MEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKY 662
            +  R  IGL +A  C++LVATDAS ++ YITRFTEE F++LI  IFIY+AI+K+I   + 
Sbjct: 560  LSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAET 619

Query: 663  YPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSK 722
            YPI+M  + + ++ Y C C  P+  N    N +     D N      +    + W+ L+ 
Sbjct: 620  YPIHMHSQLDHLSLYYCRCTLPENPN----NHTLQYWKDHN------IVTAEVHWANLTV 669

Query: 723  KECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALV 778
             EC    G  +G++C     + PD+   S ILFF T+ ++ TLK FK SRYFPT+VR++V
Sbjct: 670  SECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMV 729

Query: 779  ADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILP 838
            +DF++  +I     ID   G+ +PKL VPSV KPTR DRGW + P G NPWW   A+I+P
Sbjct: 730  SDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIP 789

Query: 839  ALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVI 898
            ALL TILIFMDQQITAVI+NRKE+KLKK  GYHLDL  V I++ +CS MGLPW+VAATV+
Sbjct: 790  ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849

Query: 899  SIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYG 958
            SI H++SLK+E+E SAPGEQP+FLG+REQRVTG+++F+L G SVF+  ILK IP+PVLYG
Sbjct: 850  SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909

Query: 959  VFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIH 1018
            VFLYMGV+SL GIQ                F++R KLF MPAKHQPD  +LRHVPLR++H
Sbjct: 910  VFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVH 953

Query: 1019 LFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEK 1078
            LFTL+Q+ CL +LW++K++ AAI+FP+M+L L+ VR+++D  FS+ +L+W+D+++PE +K
Sbjct: 954  LFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKK 1013

Query: 1079 KETDKKRKRKK 1089
            K+ D  +K+ K
Sbjct: 1014 KKLDDAKKKAK 1024


>gi|151101449 solute carrier family 4, sodium bicarbonate
            cotransporter, member 9 [Homo sapiens]
          Length = 959

 Score =  842 bits (2174), Expect = 0.0
 Identities = 466/993 (46%), Positives = 607/993 (61%), Gaps = 102/993 (10%)

Query: 93   PAAEQLQDILGEEDEAP-NPTLFTEMDTLQHDGDQMEWKESARWIKFEEKVEEGGERWSK 151
            P+ +   D   +E   P +P LF +++ L      +EW+E+ RW+ FEEK+E    RWS 
Sbjct: 35   PSPDGPSDTESKELGVPKDPLLFIQLNELLGWPQALEWRETGRWVLFEEKLEVAAGRWSA 94

Query: 152  PHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYV 211
            PHV TL+L SL +LR+ L  G VLLD  + SL ++++ V   +     L PELR ++  +
Sbjct: 95   PHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVES----LSPELRGQLQAL 150

Query: 212  LLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGRLC 271
            LL+R +H  +               TT   P        S H                  
Sbjct: 151  LLQRPQHYNQ---------------TTGTRPCWG-----STH------------------ 172

Query: 272  HAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAML 331
                R  +D    P  +Q +N   +K+P  +EA  VL GE+ FL QP  AFVRL    +L
Sbjct: 173  ---PRKASDNEEAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVL 229

Query: 332  GGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGID 391
            G +TEV +P+RF  +LLGP    K Y+E+GRA A L+ D  F     +A N  DL+A +D
Sbjct: 230  GSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALD 289

Query: 392  EFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNG 451
             FL+EV VLPPG WDP  RI PPK +PS  KR        L      + G          
Sbjct: 290  AFLEEVTVLPPGRWDPTARIPPPKCLPSQHKR--------LPSQQREIRGPA-------- 333

Query: 452  GGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPS 511
                               +S +D      H    EL  TGR FGGL  D++RK+PW+PS
Sbjct: 334  ---------------VPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPS 378

Query: 512  DFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFS 571
            DF D  H+Q  SA+L+IYL  +TNAITFGGLLGDATD  QGV+ESFLGTA+AG+ FCL +
Sbjct: 379  DFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMA 438

Query: 572  GQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKY 631
            GQPL ILSSTGP+L+FE+LLF FS+   LDY+ FRLW+G+  A  CL+LVAT+AS +++Y
Sbjct: 439  GQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRY 498

Query: 632  ITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTV-NTT 690
             TRFTEEGF  LIS IFIYDA+ KM+     YPI    KP   + Y C C  P    N +
Sbjct: 499  FTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPGS-SAYGCLCQYPGPGGNES 554

Query: 691  VFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFIL 750
             +  + P   D   S+    +L  ++ SLL   EC   GG   G  C  +PD+A  S +L
Sbjct: 555  QWIRTRPKDRDDIVSM----DLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLL 610

Query: 751  FFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVPSVI 810
            F  ++   + LK  K SR+FP+ VR  ++DFS V +IL+ CG+DA  GL TPKL VP   
Sbjct: 611  FLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREF 670

Query: 811  KPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGY 870
            KPT P RGW V+PFG NPWW   A+ LPALL++ILIFMDQQITAVI+NR E +L+K AG+
Sbjct: 671  KPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGF 730

Query: 871  HLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVT 930
            HLDLF V +LM L S +GLPWYV+ATVIS+AH+DSL+ E+   APGE+P FLG+REQR+T
Sbjct: 731  HLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLT 790

Query: 931  GIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFW 990
            G++VFILTG S+FLAP+LK IP+PVLYG+FLYMGVA+L+ IQ                F 
Sbjct: 791  GLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQ----------------FT 834

Query: 991  ERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGL 1050
             R KL LMPAKHQPD   LRHVPL R+HLFT +Q+ CL +LWI+KST AAIIFP+M+LGL
Sbjct: 835  NRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGL 894

Query: 1051 IIVRRLLDFIFSQHDLAWIDNILPEKEKKETDK 1083
            + VR+ L+ +FS  +L W+D ++PE+E+   +K
Sbjct: 895  VGVRKALERVFSPQELLWLDELMPEEERSIPEK 927


>gi|134288865 solute carrier family 4, sodium bicarbonate
            cotransporter, member 7 [Homo sapiens]
          Length = 1214

 Score =  821 bits (2121), Expect = 0.0
 Identities = 419/842 (49%), Positives = 573/842 (68%), Gaps = 79/842 (9%)

Query: 294  FMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGR 353
            FM+KIP  +EASNVLVGEVDFL++P IAFVRL  + +L G+TEVPVPTRFLF+LLGP+G+
Sbjct: 418  FMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGK 477

Query: 354  AKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEP 413
            A  Y+EIGR+IATLM D++F DVAYKA++R DL++GIDEFLD+V VLPPGEWDP+IRIEP
Sbjct: 478  APQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEP 537

Query: 414  PKKVPSADKRK-SVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
            PK VPS +KRK  VF        NGS    G  P                          
Sbjct: 538  PKSVPSQEKRKIPVFH-------NGSTPTLGETP-------------------------- 564

Query: 473  GDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGC 532
                   A H  G EL  TGR FGGL LDIKRK P+F SDF D   +Q +++ILF+Y  C
Sbjct: 565  -----KEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCAC 619

Query: 533  ITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLF 592
            ++  ITFGGLLG+AT+     +ES  G ++ G  + LF+GQPL IL STGP+L+FEK+L+
Sbjct: 620  MSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILY 679

Query: 593  DFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDA 652
             F +   L Y+  R  IGL ++  C++LVATDAS ++ YITRFTEE F+ LI  IFIY+A
Sbjct: 680  KFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEA 739

Query: 653  IKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNL 712
            ++K+    + Y  NM    + +T+Y C C  P            P   +   + +   N+
Sbjct: 740  LEKLFDLGETYAFNMHNNLDKLTSYSCVCTEP------------PNPSNETLAQWKKDNI 787

Query: 713  TA--LDWSLLSKKECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKF 766
            TA  + W  L+  EC    G  LG++C     +IPD+     ILFF T+ ++  LK+FK 
Sbjct: 788  TAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKT 847

Query: 767  SRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGK 826
             RYFPTKVR+ ++DF++  +I++   ID   G+ +PKLHVP   +PT P+RGW ++P G 
Sbjct: 848  KRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGD 907

Query: 827  NPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSF 886
            NPWW    + +PALL TILIFMDQQITAVI+NRKE+KLKK AGYHLDL  VG+++ +CS 
Sbjct: 908  NPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSV 967

Query: 887  MGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAP 946
            MGLPW+VAATV+SI+H++SLK+E+E SAPGEQP+FLG+REQRVTG+++FIL G+SVF+  
Sbjct: 968  MGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTS 1027

Query: 947  ILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDH 1006
            +LK IP+PVLYGVFLYMGV+SL GIQ+                ++R KLF MPAKHQPD 
Sbjct: 1028 VLKFIPMPVLYGVFLYMGVSSLKGIQL----------------FDRIKLFGMPAKHQPDL 1071

Query: 1007 AFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDL 1066
             +LR+VPL ++H+FT++Q+ CL +LW++K + AA++FP+M+L L+ VR+L+D  F++ +L
Sbjct: 1072 IYLRYVPLWKVHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKREL 1131

Query: 1067 AWIDNILPE-KEKKETDKKRKRKKGAH---EDCDEEPQFP--PPSVIKIPMESVQSDPQN 1120
            +W+D+++PE K+KKE DKK+K K+ A    +D D+    P    S+++IP+++++  P  
Sbjct: 1132 SWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDDDTVHLPFEGGSLLQIPVKALKYSPDK 1191

Query: 1121 GI 1122
             +
Sbjct: 1192 PV 1193



 Score =  154 bits (389), Expect = 5e-37
 Identities = 96/235 (40%), Positives = 132/235 (56%), Gaps = 30/235 (12%)

Query: 31  IHIGLPVPTYPQ--RKTDQKGHLSGLQKVHWGLRPDQPQQELTGPGSGASSQDSSMDLIS 88
           ++IG+ VP   +  R+   +GH     K H   R D+   +  G  S +    S      
Sbjct: 43  VYIGVHVPFSKESRRRHRHRGH-----KHHHRRRKDKESDKEDGRESPSYDTPS------ 91

Query: 89  RTRSPAAEQLQDILGEEDEAPNPT---LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEE 144
                  +++Q ILG ED+        LFTEMD L + DG++ EWKE+ARW+KFEE VE+
Sbjct: 92  -------QRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVED 144

Query: 145 GGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPEL 204
           GG+RWSKP+V+TLSLHSLFELR+C+  GTV+LD+ + +L +I D V++  I  G L   +
Sbjct: 145 GGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESI 204

Query: 205 RERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSPARSPGAGPSLH 253
           RE V   LL+RH HQ +K      P+ RS ADIGK  S  +       G   S H
Sbjct: 205 RENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRH 259


>gi|157671951 solute carrier family 4, anion exchanger, member 3
            isoform 1 [Homo sapiens]
          Length = 1232

 Score =  598 bits (1541), Expect = e-170
 Identities = 369/976 (37%), Positives = 536/976 (54%), Gaps = 103/976 (10%)

Query: 113  LFTEMDTLQHDGDQM-EWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQT 171
            +F E++ L  D  Q   W+E+ARWIKFEE VEE  ERW KPHV++LS  SL ELR  +  
Sbjct: 321  VFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 380

Query: 172  GTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIH 225
            G  LLDL+  +LP I   V+E  I    +RPE R  V   LL +H H          P +
Sbjct: 381  GAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRN 440

Query: 226  RSLADIGKSVSTTNRSPARSP-GAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLT 284
             S + +   +   + +P+  P GA P++    +DL    +  +     A+ + ++     
Sbjct: 441  PSSSSMNSVLGNHHPTPSHGPDGAVPTM---ADDLG-EPAPLWPHDPDAKEKPLH----M 492

Query: 285  PNTDQRKNKFMK---KIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPT 341
            P  D  + K +K   KIP+D+EA+ VLVG V FL+QP  AFVRL ++ +L  V EVPVP 
Sbjct: 493  PGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPV 552

Query: 342  RFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLP 401
            RFLF++LGPS  +  Y+E+GR+IATLM D LF + AY+A +R+DL++ I EFLD  IV+P
Sbjct: 553  RFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIP 612

Query: 402  PGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGG 461
            P E +    +           RK      E  ++  +  GG  APG              
Sbjct: 613  PSEVEGRDLLRSVAAFQRELLRKR--REREQTKVEMTTRGGYTAPG----------KELS 660

Query: 462  AGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQS 521
               GG+  T   D             L+ TG  FGGL  D++R+ P +PSD  D  H Q 
Sbjct: 661  LELGGSEATPEDDP------------LLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQC 708

Query: 522  ISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSST 581
            ++A+LFIY   ++ AITFGGLLG+ T+   GV E  + TA+ G LF L   QPL+++  +
Sbjct: 709  VAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFS 768

Query: 582  GPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFS 641
            GP+L+FE+  F F +   L+Y+  R+W+GL   V  L LVA + SF+++YI+ FT+E F+
Sbjct: 769  GPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFA 828

Query: 642  TLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPD 701
             LIS IFIY+   K+   F  +P+        +  Y  E     +++  +    + L P 
Sbjct: 829  FLISLIFIYETFYKLYKVFTEHPL--------LPFYPPEGALEGSLDAGLEPNGSALPPT 880

Query: 702  TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTL 761
                                              S +  P+ AL+S IL  GT+ +   L
Sbjct: 881  EGPP------------------------------SPRNQPNTALLSLILMLGTFFIAFFL 910

Query: 762  KKFKFSRYFPTKVRALVADFSIVFSILMFCGID-ACFGLETPKLHVPSVIKPTRPD-RGW 819
            +KF+ SR+   K R ++ DF I  SIL+   +D +     T KL VP+ +  T PD R W
Sbjct: 911  RKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSW 970

Query: 820  FVAPFGKN---PWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFW 876
            F+ P G     P W+  A+ +PALLV ILIFM+ QITA+IV++K  +L K +G+HLDL  
Sbjct: 971  FIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLL 1030

Query: 877  VGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFI 936
            +G L  LC   GLPW  AATV S+ H+++L +     APG++PQ   VREQRVTG+++  
Sbjct: 1031 IGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIAS 1090

Query: 937  LTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLF 996
            L G+S+ +  +L+ IPL VL+G+FLYMGV SL+GIQ+                 +R  L 
Sbjct: 1091 LVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLS----------------QRLLLI 1134

Query: 997  LMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRR- 1055
            LMPAKH P+  ++  V   R+HLFT +Q+ C+A+LW++KST A++ FP ++L  + +R  
Sbjct: 1135 LMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHC 1194

Query: 1056 LLDFIFSQHDLAWIDN 1071
            LL  +F   +L  +D+
Sbjct: 1195 LLPRLFQDRELQALDS 1210


>gi|157671953 solute carrier family 4, anion exchanger, member 3
            isoform 2 [Homo sapiens]
          Length = 1259

 Score =  598 bits (1541), Expect = e-170
 Identities = 369/976 (37%), Positives = 536/976 (54%), Gaps = 103/976 (10%)

Query: 113  LFTEMDTLQHDGDQM-EWKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQT 171
            +F E++ L  D  Q   W+E+ARWIKFEE VEE  ERW KPHV++LS  SL ELR  +  
Sbjct: 348  VFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 407

Query: 172  GTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIH 225
            G  LLDL+  +LP I   V+E  I    +RPE R  V   LL +H H          P +
Sbjct: 408  GAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRN 467

Query: 226  RSLADIGKSVSTTNRSPARSP-GAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLT 284
             S + +   +   + +P+  P GA P++    +DL    +  +     A+ + ++     
Sbjct: 468  PSSSSMNSVLGNHHPTPSHGPDGAVPTM---ADDLG-EPAPLWPHDPDAKEKPLH----M 519

Query: 285  PNTDQRKNKFMK---KIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPT 341
            P  D  + K +K   KIP+D+EA+ VLVG V FL+QP  AFVRL ++ +L  V EVPVP 
Sbjct: 520  PGGDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPV 579

Query: 342  RFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLP 401
            RFLF++LGPS  +  Y+E+GR+IATLM D LF + AY+A +R+DL++ I EFLD  IV+P
Sbjct: 580  RFLFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIP 639

Query: 402  PGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGG 461
            P E +    +           RK      E  ++  +  GG  APG              
Sbjct: 640  PSEVEGRDLLRSVAAFQRELLRKR--REREQTKVEMTTRGGYTAPG----------KELS 687

Query: 462  AGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQS 521
               GG+  T   D             L+ TG  FGGL  D++R+ P +PSD  D  H Q 
Sbjct: 688  LELGGSEATPEDDP------------LLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQC 735

Query: 522  ISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSST 581
            ++A+LFIY   ++ AITFGGLLG+ T+   GV E  + TA+ G LF L   QPL+++  +
Sbjct: 736  VAAVLFIYFAALSPAITFGGLLGEKTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFS 795

Query: 582  GPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFS 641
            GP+L+FE+  F F +   L+Y+  R+W+GL   V  L LVA + SF+++YI+ FT+E F+
Sbjct: 796  GPLLVFEEAFFKFCRAQDLEYLTGRVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFA 855

Query: 642  TLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPD 701
             LIS IFIY+   K+   F  +P+        +  Y  E     +++  +    + L P 
Sbjct: 856  FLISLIFIYETFYKLYKVFTEHPL--------LPFYPPEGALEGSLDAGLEPNGSALPPT 907

Query: 702  TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTL 761
                                              S +  P+ AL+S IL  GT+ +   L
Sbjct: 908  EGPP------------------------------SPRNQPNTALLSLILMLGTFFIAFFL 937

Query: 762  KKFKFSRYFPTKVRALVADFSIVFSILMFCGID-ACFGLETPKLHVPSVIKPTRPD-RGW 819
            +KF+ SR+   K R ++ DF I  SIL+   +D +     T KL VP+ +  T PD R W
Sbjct: 938  RKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSW 997

Query: 820  FVAPFGKN---PWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFW 876
            F+ P G     P W+  A+ +PALLV ILIFM+ QITA+IV++K  +L K +G+HLDL  
Sbjct: 998  FIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLL 1057

Query: 877  VGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFI 936
            +G L  LC   GLPW  AATV S+ H+++L +     APG++PQ   VREQRVTG+++  
Sbjct: 1058 IGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIAS 1117

Query: 937  LTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLF 996
            L G+S+ +  +L+ IPL VL+G+FLYMGV SL+GIQ+                 +R  L 
Sbjct: 1118 LVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGIQLS----------------QRLLLI 1161

Query: 997  LMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRR- 1055
            LMPAKH P+  ++  V   R+HLFT +Q+ C+A+LW++KST A++ FP ++L  + +R  
Sbjct: 1162 LMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLLLLTVPLRHC 1221

Query: 1056 LLDFIFSQHDLAWIDN 1071
            LL  +F   +L  +D+
Sbjct: 1222 LLPRLFQDRELQALDS 1237


>gi|156071474 solute carrier family 4, anion exchanger, member 2
            (erythrocyte membrane protein band 3-like 1) [Homo
            sapiens]
          Length = 1241

 Score =  593 bits (1529), Expect = e-169
 Identities = 369/1003 (36%), Positives = 550/1003 (54%), Gaps = 120/1003 (11%)

Query: 103  GEEDEAPNPT-------------LFTEMDTLQHDGDQM-EWKESARWIKFEEKVEEGGER 148
            G E   P PT             +F E++ L  D +Q  +W+E+ARWIKFEE VEE  ER
Sbjct: 300  GREGREPGPTPRARPRAPHKPHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETER 359

Query: 149  WSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERV 208
            W KPHV++LS  SL ELR  L  G VLLDLD  +LP +   V+E+ +    ++ E R  V
Sbjct: 360  WGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANV 419

Query: 209  SYVLLRRHRHQTKK-----PIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQ 263
               LL +H H + +     P + S   +G  +   +   A S        H TE L    
Sbjct: 420  LRALLLKHSHPSDEKDFSFPRNISAGSLGSLLGHHHGQGAESDP------HVTEPLM--G 471

Query: 264  SANYGRLCHAQSRSMND----ISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPF 319
                 RL   + R +        +T +  + + K ++KIP+++EA+ VLVG V+FL +P 
Sbjct: 472  GVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPT 531

Query: 320  IAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYK 379
            +AFVRL ++  L  V EVPVP RFLF+LLGPS     Y+EIGR+I+TLM D  F + AY 
Sbjct: 532  MAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYL 591

Query: 380  ARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSV 439
            A  REDL+  I+ FLD  +VLPP E    ++ E   +  +  +R+ +    E G++    
Sbjct: 592  ADEREDLLTAINAFLDCSVVLPPSE----VQGEELLRSVAHFQRQMLKKREEQGRL---- 643

Query: 440  GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIG----EELIWTGRFF 495
                  P G                 G    S+ D   +  +   G    + L  TGR F
Sbjct: 644  -----LPTGA----------------GLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPF 682

Query: 496  GGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVME 555
            GGL  D++R+ P + SDF D    Q ++A++FIY   ++ AITFGGLLG+ T +  GV E
Sbjct: 683  GGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSE 742

Query: 556  SFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAV 615
              + TA+ G +FCL   QPL+++  +GP+L+FE+  F F   N L+Y+  R+WIG     
Sbjct: 743  LIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVF 802

Query: 616  QCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFIT 675
              L++VA + SF++++++RFT+E F+ LIS IFIY+   K++  F+ +P++     N   
Sbjct: 803  LALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCSASNSSE 862

Query: 676  TYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGN 735
                E       N T   A   L P                          S  G+    
Sbjct: 863  VDGGE-------NMTWAGARPTLGPGNR-----------------------SLAGQSGQG 892

Query: 736  SCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDA 795
              +  P+ AL+S +L  GT+ +   L+KFK SR+FP ++R ++ DF +  +IL+   +D 
Sbjct: 893  KPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVD- 951

Query: 796  CFGLE---TPKLHVPSVIKPTRPD-RGWFVAPFGKN---PWWVYPASILPALLVTILIFM 848
             + +E   T KL VPS    T P+ RGW + P G+    P W+  AS+LPA+LV ILIFM
Sbjct: 952  -YSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFM 1010

Query: 849  DQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKM 908
            + QIT +I+++KE  L+K +G+HLDL  +  +  +C+  GLPW  AATV S+ H ++L +
Sbjct: 1011 ETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTV 1070

Query: 909  ETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASL 968
             ++  APG++P+   V+EQRVTG++V +L G+S+ +  +L+ IPL VL+G+FLYMGV SL
Sbjct: 1071 MSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSL 1130

Query: 969  NGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCL 1028
            NGIQ                F+ER  L LMP KH PD  +++ V   R+HLFT +Q+LCL
Sbjct: 1131 NGIQ----------------FYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCL 1174

Query: 1029 AVLWILKSTVAAIIFP-VMILGLIIVRRLLDFIFSQHDLAWID 1070
            A+LW + ST A++ FP ++IL + +   +L  IF+  ++  +D
Sbjct: 1175 ALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKCLD 1217


>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
            sapiens]
          Length = 911

 Score =  525 bits (1351), Expect = e-148
 Identities = 345/998 (34%), Positives = 515/998 (51%), Gaps = 154/998 (15%)

Query: 88   SRTRSPAAEQLQDILGEEDEAPNP---TLFTEMDTLQHD--GDQMEWKESARWIKFEEKV 142
            S+   PAA   +    +     +P    ++ E+  L  D    ++ W E+ARW++ EE +
Sbjct: 29   SQMEEPAAHDTEATATDYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENL 88

Query: 143  EEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRP 202
             E G  W +PH+S L+  SL ELR     GTVLLDL   SL  + + ++++ I +  +RP
Sbjct: 89   GENGA-WGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRP 147

Query: 203  ELRERVSYVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSL--HHSTEDLR 260
            + RE +   LL +H H  +     +L  +  +V T +  P++     P L  H S E   
Sbjct: 148  QDREELLRALLLKHSHAGEL---EALGGVKPAVLTRSGDPSQ-----PLLPQHSSLETQL 199

Query: 261  MRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFI 320
              +  + G   H+ S                   ++KIP DSEA+ VLVG  DFL+QP +
Sbjct: 200  FCEQGDGGTEGHSPSG-----------------ILEKIPPDSEATLVLVGRADFLEQPVL 242

Query: 321  AFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKA 380
             FVRL ++A L  V E+PVP RFLF+LLGP      Y ++GRA ATLM + +F   AY A
Sbjct: 243  GFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMA 301

Query: 381  RNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQ--MNGS 438
            ++R +L+  ++ FLD  +VL            PP   PS    +++ SL  + +  +   
Sbjct: 302  QSRGELLHSLEGFLDCSLVL------------PPTDAPS---EQALLSLVPVQRELLRRR 346

Query: 439  VGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGL 498
                   P           S    G    GG                + L  TG+ FGGL
Sbjct: 347  YQSSPAKPD----------SSFYKGLDLNGGPD--------------DPLQQTGQLFGGL 382

Query: 499  CLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFL 558
              DI+R+ P++ SD  D F  Q ++A++FIY   ++ AITFGGLLG+ T N  GV E  +
Sbjct: 383  VRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLI 442

Query: 559  GTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCL 618
             TA+ G LF L   QPL+++  +GP+L+FE+  F F + NGL+Y+  R+WIG    +  +
Sbjct: 443  STAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVV 502

Query: 619  ILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYK 678
            ++VA + SF++++I+R+T+E FS LIS IFIY+   K+I  F+ +P+             
Sbjct: 503  LVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQK----------- 551

Query: 679  CECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCK 738
                   T N  V     P  P                                      
Sbjct: 552  -------TYNYNVLMVPKPQGP-------------------------------------- 566

Query: 739  FIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACF- 797
             +P+ AL+S +L  GT+   + L+KFK S YFP K+R ++ DF +  SIL+   +D    
Sbjct: 567  -LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQ 625

Query: 798  GLETPKLHVPSVIKPTRPD-RGWFVAPFGKN---PWWVYPASILPALLVTILIFMDQQIT 853
               T KL VP   K +    RGW + P G     P W+  AS LPALLV ILIF++ QIT
Sbjct: 626  DTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQIT 685

Query: 854  AVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETS 913
             +IV++ E K+ K +G+HLDL  V  +  + +  G+PW  A TV S+ H ++L +  + S
Sbjct: 686  TLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKAS 745

Query: 914  APGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQM 973
             PG   Q   V+EQR++G++V +L G+S+ + PIL  IPL VL+G+FLYMGV SL+GIQ+
Sbjct: 746  TPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQL 805

Query: 974  GTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWI 1033
                            ++R  L   P K+ PD  +++ V   R+HLFT +QI+CLAVLW+
Sbjct: 806  ----------------FDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWV 849

Query: 1034 LKSTVAAIIFP-VMILGLIIVRRLLDFIFSQHDLAWID 1070
            +KST A++  P V+IL + + R LL  IF   +L  +D
Sbjct: 850  VKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD 887


>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
          Length = 891

 Score =  212 bits (539), Expect = 2e-54
 Identities = 162/576 (28%), Positives = 274/576 (47%), Gaps = 57/576 (9%)

Query: 494  FFGGLCLDIKRKLPWFPSDFYDGFHIQS------ISAILFIYLGCITNAITFGGLLGDAT 547
            F  G+  DI R+ P +P DF DG   ++      I+  LF+Y  C+   I FG L  + T
Sbjct: 342  FGKGIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENT 401

Query: 548  DNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRL 607
            D    V ++  G ++ G L+ LFSGQPL+IL +T P+ ++ +++        LD+  F  
Sbjct: 402  DGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYA 461

Query: 608  WIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAF-KYYPIN 666
            W GL ++    +    + S ++    R TEE  +  IS  F+ DA+K  +  F KYY   
Sbjct: 462  WTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKYY--- 518

Query: 667  MDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECL 726
                 +++  Y        T  T+   + + L    NASL+  LN + L  +  ++    
Sbjct: 519  ---YGHYLDDY-------HTKRTSSLVSLSGLGASLNASLHTALNASFL--ASPTELPSA 566

Query: 727  SYGGRLLGNSCKFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFS 786
            ++ G+            A++S ++  GT  +  TL +FK S Y    VR +++D ++  +
Sbjct: 567  THSGQA----------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIA 616

Query: 787  ILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILI 846
            +L F  I +  G    ++   S  +    +  + +A            ++    L+++L 
Sbjct: 617  VLAFSLISS-HGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLF 672

Query: 847  FMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSL 906
            F++Q + A +VN  EN+L K   YH DL  + I+    S  GLPW  AA   S  H+ +L
Sbjct: 673  FIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRAL 732

Query: 907  KMETETSAPGE-QPQFLGVREQRVTGIIVFILTGISVFLAPI-LKCIPLPVLYGVFLYMG 964
             +  E    G      + V+E R+T +   +L G+S+ L P+ L+ IP PVLYG+FLY+ 
Sbjct: 733  ALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIA 792

Query: 965  VASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFT--- 1021
            + SL+G Q+                 +R  L L      P   ++R VP R+IH FT   
Sbjct: 793  LTSLDGNQL----------------VQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQ 836

Query: 1022 LVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLL 1057
            ++Q+L L    +       +IFP++++ +I +R +L
Sbjct: 837  VLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYIL 872


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 32/65 (49%), Positives = 39/65 (60%), Gaps = 1/65 (1%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTG 492
           G   G+ GGG G+ GGG+GGG GGGSG   GSGG+ G  SG  GE    +  GEE   +G
Sbjct: 552 GGSGGNYGGGSGS-GGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSG 610

Query: 493 RFFGG 497
             +GG
Sbjct: 611 GGYGG 615



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 26/44 (59%), Positives = 28/44 (63%), Gaps = 1/44 (2%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G   GS GGG G+ GGG+GGG GGGSGGG   G  GG S G  G
Sbjct: 514 GGSGGSYGGGSGS-GGGSGGGYGGGSGGGHSGGSGGGHSGGSGG 556



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 25/46 (54%), Positives = 31/46 (67%), Gaps = 2/46 (4%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGSGGAGGTSSGDDG 476
           G  +GS GG GG+ GGG+G GG  GGG GGG+G G +GG+  G  G
Sbjct: 507 GGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 26/44 (59%), Positives = 29/44 (65%), Gaps = 1/44 (2%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G  +GS GG GG  GGG+GGG  GGSGGG  SGG+GG   G  G
Sbjct: 521 GGGSGSGGGSGGGYGGGSGGGHSGGSGGG-HSGGSGGNYGGGSG 563



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 25/50 (50%), Positives = 26/50 (52%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482
           G   G  GG GG   GG+GG  GGGSG G GSGG  G  SG  G     H
Sbjct: 537 GSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSH 586



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 6/66 (9%)

Query: 433 GQMNGSVGGGGGAPGGGNGG-GGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWT 491
           G   G  GGG G+ GG  G  GGG GSGGG+G G  GG+  G  G     H  G     +
Sbjct: 500 GGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGG-----S 554

Query: 492 GRFFGG 497
           G  +GG
Sbjct: 555 GGNYGG 560



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 25/41 (60%), Positives = 28/41 (68%), Gaps = 1/41 (2%)

Query: 437 GSVGGGGGA-PGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           GS GG GG+  GGG+GGG GGGSG   GSGG+ G  SG  G
Sbjct: 488 GSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGG 528



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 22/41 (53%), Positives = 25/41 (60%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           G   GS GG GG  GGG+ GG GGG  GG+G    GG+ SG
Sbjct: 525 GSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSG 565



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 28/68 (41%), Positives = 31/68 (45%), Gaps = 6/68 (8%)

Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG------EMPA 480
           F  A  G  + S G GGG  GG  GG GGG   G  G GG GG + G DG      E   
Sbjct: 97  FGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKST 156

Query: 481 MHEIGEEL 488
           M E+   L
Sbjct: 157 MQELNSRL 164



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 2/47 (4%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGSGGAGGTSSGDDGE 477
           G  +GS GG GG+ GGG+G GG  GG  GGG  + G+GG   G  G+
Sbjct: 573 GGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGK 619



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 20/40 (50%), Positives = 22/40 (55%)

Query: 437 GSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G  GG GG+ G G+ GG GG  GGG   GG GG S    G
Sbjct: 476 GGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGG 515



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 24/47 (51%), Positives = 28/47 (59%), Gaps = 3/47 (6%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGS-GGAGGTSSGDDG 476
           G   GS G G     GG+ GGG  GGG GGG+GS GG+GG+  G  G
Sbjct: 479 GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG 525



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 28/56 (50%), Positives = 29/56 (51%), Gaps = 9/56 (16%)

Query: 427 FSLAELGQMNGSVGGG----GGAPGGGNGGGGGGGSGGGAGSGG--AGGTSSGDDG 476
           FS + LG   G  GGG    GGA GGG    GG G G G GSGG   GG  SG  G
Sbjct: 81  FSASSLG---GGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGG 133



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 19/37 (51%), Positives = 21/37 (56%)

Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G GGG      GGG GGGS G  G+ G G +SSG  G
Sbjct: 76  GSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFG 112



 Score = 37.4 bits (85), Expect = 0.082
 Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 4/53 (7%)

Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGGGG----GGSGGGAGSGGAGGTSSGDDG 476
           +L E GQ +    G G    GG GG GG    G  GG  GS G GG+  G  G
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGG 508



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/36 (50%), Positives = 20/36 (55%)

Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           GGGG+ G   GGG GGG    +  GG GG S G  G
Sbjct: 64  GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGG 99



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 18/44 (40%), Positives = 20/44 (45%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G   G   GGG +     GG GGG  G G  SGG   +S G  G
Sbjct: 70  GYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGG 113



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 27/96 (28%)

Query: 427 FSLAELGQMNGSVGGGGGAPGGGN-----------GGGGGGGS-------GGGA------ 462
           FS + L +  G  GGGGG   GG+           GGGGGGG        GGG+      
Sbjct: 6   FSSSYLSRSGG--GGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGR 63

Query: 463 GSGGAGGTS-SGDDGEMPAMHEIGEELIWTGRFFGG 497
           G GG+ G S  G  G   +   +G       R FGG
Sbjct: 64  GGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGG 99



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 17/32 (53%), Positives = 20/32 (62%), Gaps = 2/32 (6%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGS 464
           G+  GS GGG  A   G+GGG GGGSG  + S
Sbjct: 594 GESGGSYGGGEEA--SGSGGGYGGGSGKSSHS 623



 Score = 30.4 bits (67), Expect = 10.0
 Identities = 19/51 (37%), Positives = 21/51 (41%), Gaps = 8/51 (15%)

Query: 434 QMNGSVGGGGGAPGGGNGGGGGG--------GSGGGAGSGGAGGTSSGDDG 476
           Q + S     G  GGG  G GG          S GG G GG   +SSG  G
Sbjct: 5   QFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGG 55


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 29/53 (54%), Positives = 30/53 (56%), Gaps = 1/53 (1%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIG 485
           G   G   GGGG PGGG GGGGGGG GGG G G  GG   G     P MH +G
Sbjct: 146 GPGGGGGPGGGGGPGGGPGGGGGGGPGGG-GGGPGGGLLGGSAHPHPHMHSLG 197



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 25/55 (45%), Positives = 28/55 (50%)

Query: 425 SVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMP 479
           S+  +A  G    + GGGG   G G GGG GGG G G G GG GG   G  G  P
Sbjct: 124 SLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGP 178



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 22/49 (44%), Positives = 23/49 (46%)

Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           S   L  M G+ G G  A GGG   G GGG G G G G  GG   G  G
Sbjct: 121 SSPSLALMAGAGGAGAAAGGGGAHDGPGGGGGPGGGGGPGGGPGGGGGG 169


>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
          Length = 920

 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 32/57 (56%), Positives = 34/57 (59%), Gaps = 3/57 (5%)

Query: 413 PPKKVPSADKRKSVFSL--AELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA 467
           P    PSA    S  +L  AE GQ+ G  GGGGG  GGG GGGGGGG GGG G  GA
Sbjct: 422 PGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGG-GGGGGGGGGGGGGGGGGEAGA 477



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 24/100 (24%)

Query: 401 PPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGN---------- 450
           PP    P+ RI+    +       +  +    G +    G G   PG G+          
Sbjct: 377 PPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWH 436

Query: 451 --------------GGGGGGGSGGGAGSGGAGGTSSGDDG 476
                         GGGGGGG GGG G GG GG   G+ G
Sbjct: 437 TLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAG 476


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 28/59 (47%), Positives = 33/59 (55%), Gaps = 1/59 (1%)

Query: 434 QMNGSVGGGGGAPGGGNGGGGGG-GSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWT 491
           Q   +  GG GA GGG GGGGGG GSGGG  +GG GGT+ G          I + L +T
Sbjct: 792 QSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGISQHLTYT 850



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 23/47 (48%), Positives = 27/47 (57%), Gaps = 1/47 (2%)

Query: 430 AELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           A  G      GGGGG  GGG+G GGGG +GGG G+ G G  S+   G
Sbjct: 796 AASGGSGAGGGGGGGG-GGGSGSGGGGSTGGGGGTAGGGTQSTAGPG 841



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 19/41 (46%), Positives = 23/41 (56%)

Query: 436 NGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           N ++  G  A GG   GGGGGG GGG    G GG++ G  G
Sbjct: 788 NANLQSGSAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGG 828



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 22/44 (50%), Positives = 24/44 (54%)

Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTS 471
           S A  G   G  GGGGG  G G+GGGG  G GGG   GG   T+
Sbjct: 795 SAASGGSGAGGGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTA 838



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 20/40 (50%), Positives = 23/40 (57%), Gaps = 1/40 (2%)

Query: 433 GQMNGSVGGGGGAPGGGN-GGGGGGGSGGGAGSGGAGGTS 471
           G   G  GGG G+ GGG+ GGGGG   GG   + G GG S
Sbjct: 805 GGGGGGGGGGSGSGGGGSTGGGGGTAGGGTQSTAGPGGIS 844


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 24/36 (66%), Positives = 25/36 (69%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAG 468
           G      GGGGG  GGG GG GGGG GGGAG+GGAG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG 277



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 21/33 (63%), Positives = 22/33 (66%)

Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           G GG  GGG GGGGG G GGG G  GAGG  +G
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 21/33 (63%), Positives = 23/33 (69%)

Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
           GGGGG  GGG  GGGGGG G GAG  GAG  ++
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAA 283



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 19/28 (67%), Positives = 20/28 (71%)

Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
           G   PG G GGGGGGG GGG+G GG GG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGG 269



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 17/64 (26%)

Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSG-----------------GGAGSGGAGG 469
           +S    G   G  GGGGG  GGG GGGG G  G                 GG G GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302

Query: 470 TSSG 473
           +S+G
Sbjct: 303 SSAG 306



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 8/45 (17%)

Query: 440 GGGGGAPGGGNGGGG--------GGGSGGGAGSGGAGGTSSGDDG 476
           GGGGG  GG + G G        GGG   G G GGA   S    G
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 24/36 (66%), Positives = 25/36 (69%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAG 468
           G      GGGGG  GGG GG GGGG GGGAG+GGAG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG 277



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 21/33 (63%), Positives = 22/33 (66%)

Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           G GG  GGG GGGGG G GGG G  GAGG  +G
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 21/33 (63%), Positives = 23/33 (69%)

Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
           GGGGG  GGG  GGGGGG G GAG  GAG  ++
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAA 283



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 19/28 (67%), Positives = 20/28 (71%)

Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
           G   PG G GGGGGGG GGG+G GG GG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGG 269



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 17/64 (26%)

Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSG-----------------GGAGSGGAGG 469
           +S    G   G  GGGGG  GGG GGGG G  G                 GG G GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302

Query: 470 TSSG 473
           +S+G
Sbjct: 303 SSAG 306



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 8/45 (17%)

Query: 440 GGGGGAPGGGNGGGG--------GGGSGGGAGSGGAGGTSSGDDG 476
           GGGGG  GG + G G        GGG   G G GGA   S    G
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 24/36 (66%), Positives = 25/36 (69%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAG 468
           G      GGGGG  GGG GG GGGG GGGAG+GGAG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAG 277



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 21/33 (63%), Positives = 22/33 (66%)

Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           G GG  GGG GGGGG G GGG G  GAGG  +G
Sbjct: 247 GAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 21/33 (63%), Positives = 23/33 (69%)

Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
           GGGGG  GGG  GGGGGG G GAG  GAG  ++
Sbjct: 251 GGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAA 283



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 19/28 (67%), Positives = 20/28 (71%)

Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
           G   PG G GGGGGGG GGG+G GG GG
Sbjct: 242 GYSRPGAGGGGGGGGGGGGGSGGGGGGG 269



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 17/64 (26%)

Query: 427 FSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSG-----------------GGAGSGGAGG 469
           +S    G   G  GGGGG  GGG GGGG G  G                 GG G GG GG
Sbjct: 243 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG 302

Query: 470 TSSG 473
           +S+G
Sbjct: 303 SSAG 306



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 8/45 (17%)

Query: 440 GGGGGAPGGGNGGGG--------GGGSGGGAGSGGAGGTSSGDDG 476
           GGGGG  GG + G G        GGG   G G GGA   S    G
Sbjct: 294 GGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAG 338


>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
          Length = 331

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 24/35 (68%), Positives = 25/35 (71%)

Query: 438 SVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
           + GGGGG  GGG GGGGGGG GGG   GGAGG  S
Sbjct: 58  AAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRS 92



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 25/41 (60%), Positives = 27/41 (65%)

Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPA 480
           GGGGG  GGG GGGGGG  GGGAG G  GG S   + +M A
Sbjct: 61  GGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGA 101



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 23/32 (71%), Positives = 24/32 (75%), Gaps = 2/32 (6%)

Query: 442 GGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           GGG  GGG GGGGGGG GGG G GGAGG + G
Sbjct: 60  GGG--GGGGGGGGGGGGGGGVGGGGAGGGAGG 89



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 26/59 (44%), Positives = 31/59 (52%), Gaps = 7/59 (11%)

Query: 437 GSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA-------GGTSSGDDGEMPAMHEIGEEL 488
           G  GGGGG  GGG GG GGGG+GGGAG G +       G      +   P + E+  EL
Sbjct: 62  GGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEVSPEL 120



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 21/40 (52%), Positives = 23/40 (57%)

Query: 445 APGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEI 484
           A GGG GGGGGGG GGG G  G GG   G  G    + E+
Sbjct: 58  AAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSPVREL 97



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 23/49 (46%), Positives = 25/49 (51%)

Query: 431 ELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMP 479
           E G+ + S      A GGG GGGGGGG GGG G GG G       G  P
Sbjct: 45  EAGRDDRSSPAVRAAGGGGGGGGGGGGGGGGGGVGGGGAGGGAGGGRSP 93


>gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens]
          Length = 332

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 26/51 (50%), Positives = 28/51 (54%)

Query: 420 ADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGT 470
           AD       LA  G  NG+ GGGG   G G G G GGG  GGAG GG GG+
Sbjct: 20  ADSHHRSILLASSGGGNGAGGGGGAGGGSGGGNGAGGGGAGGAGGGGGGGS 70



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 25/39 (64%), Positives = 25/39 (64%), Gaps = 1/39 (2%)

Query: 438 SVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           S GGG GA GGG G GGG G G GAG GGAGG   G  G
Sbjct: 31  SSGGGNGA-GGGGGAGGGSGGGNGAGGGGAGGAGGGGGG 68


>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
          Length = 532

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)

Query: 398 IVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAEL----GQMNGSVGGGGGAPGGGNGGG 453
           +V P  E   +  + P     +A    +  +++ +    G  +G  GGG G   G  GGG
Sbjct: 440 LVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGG 499

Query: 454 GGGGSGGGAGSGGAGGTSSGDDG 476
           GG G GGG  SGG  GT+ G  G
Sbjct: 500 GGAGGGGGGSSGGGSGTAGGHSG 522



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 3/79 (3%)

Query: 401 PPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGG---G 457
           PPG   P+   +    +  A    +  + A    ++    GGG   GG  GG GGG   G
Sbjct: 437 PPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSG 496

Query: 458 SGGGAGSGGAGGTSSGDDG 476
            GGG   GG GG+S G  G
Sbjct: 497 GGGGGAGGGGGGSSGGGSG 515



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 26/42 (61%), Positives = 28/42 (66%), Gaps = 2/42 (4%)

Query: 433 GQMNGSVGGGG-GAPGGGNGGGGGGGSGGGAG-SGGAGGTSS 472
           G   GS GG G G  GGG GGGGGG SGGG+G +GG  G SS
Sbjct: 484 GAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSS 525



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 18/40 (45%), Positives = 21/40 (52%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
           G   G  G GGG  G G GGGG  G G G   G +G +S+
Sbjct: 487 GGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSGLSSN 526


>gi|109452587 family with sequence similarity 98, member B isoform 1
           [Homo sapiens]
          Length = 433

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 31/71 (43%), Positives = 34/71 (47%), Gaps = 1/71 (1%)

Query: 407 PNIRIEPPKKVPSADKRKSVFS-LAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSG 465
           PN    PP ++P   KR+         G   G  G GGG  GGG GG GGGG G G G G
Sbjct: 312 PNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371

Query: 466 GAGGTSSGDDG 476
           G GG   G  G
Sbjct: 372 GGGGWGGGGGG 382



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 25/49 (51%), Positives = 25/49 (51%), Gaps = 7/49 (14%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGG-------GGSGGGAGSGGAGGTSSGD 474
           G   G  GGGGG  GGG GG GG       GG GG  G GG GG   GD
Sbjct: 364 GGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGD 412



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 19/33 (57%), Positives = 19/33 (57%)

Query: 437 GSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
           G  GG GG  G G G   GGG GGG G GG GG
Sbjct: 397 GGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 21/42 (50%), Positives = 21/42 (50%), Gaps = 7/42 (16%)

Query: 434 QMNGSVGGGGGAPGGGNGGG-------GGGGSGGGAGSGGAG 468
           Q  G  GG GG  G G  GG       GGGG GGG G GG G
Sbjct: 388 QGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 18/29 (62%), Positives = 18/29 (62%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGG 461
           G   G  G G G P GG GGGGGGG GGG
Sbjct: 400 GGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 26/44 (59%), Positives = 29/44 (65%), Gaps = 3/44 (6%)

Query: 433 GQMNGSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           G   G  GGG   GG+ GGG+GGG GG SGGG G G +GG SSG
Sbjct: 467 GSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 28/48 (58%), Positives = 31/48 (64%), Gaps = 3/48 (6%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGG---GGGSGGGAGSGGAGGTSSGDDGE 477
           G   GS GGGGG  GGG+ GGG   GGG GGG+ SGG   +SSG  GE
Sbjct: 529 GYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGE 576



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 26/46 (56%), Positives = 29/46 (63%), Gaps = 2/46 (4%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGG--GGGSGGGAGSGGAGGTSSGDDG 476
           G   G  G  GG  GGG+ GGG  GGG GGG+ SGG GG+SSG  G
Sbjct: 486 GHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYG 531



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 25/40 (62%), Positives = 29/40 (72%), Gaps = 2/40 (5%)

Query: 436 NGSVGGGGGAPGGGNGGGGGGGSGGGAGSGG--AGGTSSG 473
           + S G GGG+ GGG GG GGG SGGG+ SGG   GG+SSG
Sbjct: 525 SSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSG 564



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 27/43 (62%), Positives = 29/43 (67%), Gaps = 3/43 (6%)

Query: 437 GSVGGG-GGAPGGGNGGGGGGGSGGGAGSGG--AGGTSSGDDG 476
           GS GGG GG  GG +GGG GGGS GG  SGG   GG+SSG  G
Sbjct: 481 GSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHG 523



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)

Query: 433 GQMNGSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G   G  GGG   GG+ GGG GGG   G  GG+ SGG GG SSG  G
Sbjct: 493 GSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGG 539



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 27/50 (54%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 428 SLAELGQMNGSVGGGGGAPGGGNGGG-GGGGSGGGAGSGGAGGTSSGDDG 476
           SL E    +G  G GGG+ GGG GGG  GGGS GG   GG GG+S G  G
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYG 500



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 22/39 (56%), Positives = 24/39 (61%)

Query: 438 SVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           S GG GG+  GG GGG  GG GGG G G +GG SS   G
Sbjct: 518 SSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGG 556



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 22/42 (52%), Positives = 25/42 (59%), Gaps = 2/42 (4%)

Query: 437 GSVGGG--GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           GS GGG  GG+  GG+GG   GG GGG+  GG GG   G  G
Sbjct: 507 GSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSG 548



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 24/42 (57%), Positives = 27/42 (64%), Gaps = 3/42 (7%)

Query: 437 GSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDD 475
           GS GGG   GG+ GGG  GGGG G G G G GG GG  SG++
Sbjct: 105 GSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSGNE 146



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/45 (60%), Positives = 29/45 (64%), Gaps = 5/45 (11%)

Query: 437 GSVGG--GGGAPGGGN-GGG--GGGGSGGGAGSGGAGGTSSGDDG 476
           GS GG  GGG+ GGG+ GGG  GGGG GGG   GG GG   GD G
Sbjct: 96  GSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGG 140



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 20/46 (43%), Positives = 25/46 (54%)

Query: 441 GGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGE 486
           GGG + GGG G GGG   GG +  GG GG SS    +  +   +GE
Sbjct: 531 GGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGE 576



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 23/47 (48%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 433 GQMNGSVGGG---GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G   GS GGG   GG  GG + GG GG S GG G G +GG   G  G
Sbjct: 498 GYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGG 544



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 21/43 (48%), Positives = 23/43 (53%), Gaps = 2/43 (4%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA--GGTSSG 473
           G   GS  GG G    G  GGG  G GGG   GG+  GG+SSG
Sbjct: 512 GYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSG 554



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 25/53 (47%), Positives = 28/53 (52%), Gaps = 9/53 (16%)

Query: 428 SLAELGQMNGSVGGG---GGAPGG----GNGGGG--GGGSGGGAGSGGAGGTS 471
           S   +    GS+GGG   GG  GG    G+ GGG  GG SGG  G GG GG S
Sbjct: 32  SSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGS 84



 Score = 37.4 bits (85), Expect = 0.082
 Identities = 17/40 (42%), Positives = 20/40 (50%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSS 472
           G   G   GGG + GGG GGG   G    + SG  G +SS
Sbjct: 540 GGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSS 579



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 22/42 (52%), Positives = 22/42 (52%), Gaps = 12/42 (28%)

Query: 440 GGGGGAPGGGNGGGGG----------GGSGGGAGSGGAGGTS 471
           GGGGG  GGG GGGGG          G  GGG  SGG  G S
Sbjct: 17  GGGGG--GGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGS 56



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 22/44 (50%), Positives = 24/44 (54%), Gaps = 4/44 (9%)

Query: 437 GSVGGG--GGAPGG--GNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           GS GGG  GG+ GG  G GG GGG   G  GS   GG+  G  G
Sbjct: 60  GSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFG 103



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 25/57 (43%), Positives = 26/57 (45%), Gaps = 20/57 (35%)

Query: 440 GGGGGAPGGGNG-------------GGG---GGGSGG----GAGSGGAGGTSSGDDG 476
           GGGGG  GGG G             GGG   GG SGG    G+  GG  G SSG  G
Sbjct: 19  GGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 23/61 (37%), Positives = 26/61 (42%), Gaps = 20/61 (32%)

Query: 436 NGSVGGGGGAPGGGN-------------GGG-------GGGGSGGGAGSGGAGGTSSGDD 475
           +G  GGGGG  GGG              GGG       GG  S G +G G  GG+S G  
Sbjct: 16  SGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYG 75

Query: 476 G 476
           G
Sbjct: 76  G 76



 Score = 33.9 bits (76), Expect = 0.90
 Identities = 24/57 (42%), Positives = 24/57 (42%), Gaps = 13/57 (22%)

Query: 433 GQMNGSVGGGGGAPGGGNG-----------GGGGGGS--GGGAGSGGAGGTSSGDDG 476
           G   GS GG GG  G G G           GG  GGS  GG  G G  GG S G  G
Sbjct: 65  GCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGG 121


>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
          Length = 474

 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 27/68 (39%), Positives = 36/68 (52%), Gaps = 2/68 (2%)

Query: 407 PNIRIEPPKKVPS--ADKRKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGS 464
           P+ +  P KKV S  A+   S  + ++ G+    VGG GG   GG GGGG   +GGG G 
Sbjct: 124 PDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGG 183

Query: 465 GGAGGTSS 472
              GG +S
Sbjct: 184 ASGGGANS 191


>gi|12056465 fibrillarin [Homo sapiens]
          Length = 321

 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 25/44 (56%), Positives = 26/44 (59%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           G   G  G GGG  G G GGGGGGG GGG G GG G  S G+ G
Sbjct: 28  GGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRG 71



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 22/41 (53%), Positives = 23/41 (56%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           G+  G  G G G  GGG GGGGGG  GGG  SGG  G   G
Sbjct: 35  GRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRG 75



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 25/51 (49%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 437 GSVGGGGGAPGGGNGGGGGG---GSGGGAGSGGAGGTSSGDDGEM-PAMHE 483
           G  GGGGG  GGG G GGGG   G   G G GG  G  SG +  + P  HE
Sbjct: 44  GRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHE 94



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 22/45 (48%), Positives = 22/45 (48%), Gaps = 5/45 (11%)

Query: 437 GSVGGGGGAPGGGNGGGGGG-----GSGGGAGSGGAGGTSSGDDG 476
           G  GG GG  G G G G GG     G GGG G GG GG   G  G
Sbjct: 19  GDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGG 63



 Score = 37.4 bits (85), Expect = 0.082
 Identities = 18/37 (48%), Positives = 18/37 (48%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGG 469
           G   G  G GG   G G GGG  G   GG G GG GG
Sbjct: 19  GDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGG 55



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 21/45 (46%), Positives = 21/45 (46%), Gaps = 5/45 (11%)

Query: 437 GSVGGGGG-APGGGNGGGGGGGSGGGAGSG----GAGGTSSGDDG 476
           G  GG GG    GG GG GG G G G G G    G GG   G  G
Sbjct: 10  GGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGG 54



 Score = 34.3 bits (77), Expect = 0.69
 Identities = 17/34 (50%), Positives = 17/34 (50%)

Query: 440 GGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSG 473
           GGG G  GG    GG GG GG  G  G GG   G
Sbjct: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRG 42



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 16/34 (47%), Positives = 16/34 (47%)

Query: 443 GGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDG 476
           GG  GG  G G  GG GG  G GG  G   G  G
Sbjct: 9   GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRG 42


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 25/41 (60%), Positives = 26/41 (63%), Gaps = 4/41 (9%)

Query: 433 GQMNGSVGGGGGAPGGG----NGGGGGGGSGGGAGSGGAGG 469
           G    S GG GGA GGG     GGGGGGG GGG G+ GAGG
Sbjct: 204 GSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGG 244



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 23/38 (60%), Positives = 26/38 (68%)

Query: 430 AELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGA 467
           A  G   G+ GGG  + GGG GGGGGGG GG AG+GGA
Sbjct: 208 ASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGA 245



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 1/47 (2%)

Query: 437 GSVGGGGGAPGGGNGGGGGG-GSGGGAGSGGAGGTSSGDDGEMPAMH 482
           G+ G    + GG  G GGGG  S GG G GG GG   G  G   A+H
Sbjct: 201 GAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALH 247



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 20/64 (31%), Positives = 24/64 (37%), Gaps = 11/64 (17%)

Query: 433 GQMNGSVGGGGGAPGGGNGGGGGGGS-----------GGGAGSGGAGGTSSGDDGEMPAM 481
           G  +    G  GA G      GG G            GGG G GG GG ++G  G +   
Sbjct: 190 GHHHHPTAGAPGAAGSAAASAGGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPH 249

Query: 482 HEIG 485
           H  G
Sbjct: 250 HAAG 253


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,732,029
Number of Sequences: 37866
Number of extensions: 2363618
Number of successful extensions: 38331
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 481
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 18189
Number of HSP's gapped (non-prelim): 8585
length of query: 1137
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1024
effective length of database: 13,968,660
effective search space: 14303907840
effective search space used: 14303907840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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