BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|42544142 regulator of G-protein signalling 19 interacting protein 1 isoform 2 [Homo sapiens] (236 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|42544142 regulator of G-protein signalling 19 interacting pro... 472 e-133 gi|42544140 regulator of G-protein signalling 19 interacting pro... 472 e-133 gi|42544146 regulator of G-protein signalling 19 interacting pro... 472 e-133 gi|42544144 regulator of G-protein signalling 19 interacting pro... 472 e-133 gi|42544149 regulator of G-protein signalling 19 interacting pro... 472 e-133 gi|5031715 regulator of G-protein signalling 19 interacting prot... 472 e-133 gi|41393579 PDZ domain protein GIPC2 [Homo sapiens] 322 1e-88 gi|18959204 GIPC PDZ domain containing family, member 3 [Homo sa... 316 1e-86 gi|87196343 PDZ domain containing 2 [Homo sapiens] 51 1e-06 gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] 42 6e-04 gi|148746189 multiple PDZ domain protein [Homo sapiens] 41 8e-04 gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 41 0.001 gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens] 41 0.001 gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens] 41 0.001 gi|66346708 membrane associated guanylate kinase, WW and PDZ dom... 40 0.002 gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 40 0.002 gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 40 0.002 gi|218505835 membrane-associated guanylate kinase-related 3 iso... 40 0.002 gi|155969695 membrane-associated guanylate kinase-related 3 iso... 40 0.002 gi|223890252 glutamate receptor interacting protein 1 [Homo sapi... 40 0.002 gi|186972120 calcium/calmodulin-dependent serine protein kinase ... 40 0.002 gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 39 0.004 gi|122937249 glutamate receptor interacting protein 2 [Homo sapi... 39 0.004 gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] 39 0.005 gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni... 38 0.007 gi|186700629 calcium/calmodulin-dependent serine protein kinase ... 38 0.009 gi|186700627 calcium/calmodulin-dependent serine protein kinase ... 38 0.009 gi|112382257 InaD-like [Homo sapiens] 38 0.009 gi|154354983 regulating synaptic membrane exocytosis 2 isoform a... 37 0.015 gi|154354981 regulating synaptic membrane exocytosis 2 isoform b... 37 0.015 >gi|42544142 regulator of G-protein signalling 19 interacting protein 1 isoform 2 [Homo sapiens] Length = 236 Score = 472 bits (1214), Expect = e-133 Identities = 236/236 (100%), Positives = 236/236 (100%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI Sbjct: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA Sbjct: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 >gi|42544140 regulator of G-protein signalling 19 interacting protein 1 isoform 1 [Homo sapiens] Length = 333 Score = 472 bits (1214), Expect = e-133 Identities = 236/236 (100%), Positives = 236/236 (100%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI Sbjct: 98 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 157 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA Sbjct: 158 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 217 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG Sbjct: 218 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 277 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY Sbjct: 278 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333 >gi|42544146 regulator of G-protein signalling 19 interacting protein 1 isoform 2 [Homo sapiens] Length = 236 Score = 472 bits (1214), Expect = e-133 Identities = 236/236 (100%), Positives = 236/236 (100%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI Sbjct: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA Sbjct: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 >gi|42544144 regulator of G-protein signalling 19 interacting protein 1 isoform 1 [Homo sapiens] Length = 333 Score = 472 bits (1214), Expect = e-133 Identities = 236/236 (100%), Positives = 236/236 (100%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI Sbjct: 98 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 157 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA Sbjct: 158 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 217 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG Sbjct: 218 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 277 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY Sbjct: 278 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333 >gi|42544149 regulator of G-protein signalling 19 interacting protein 1 isoform 2 [Homo sapiens] Length = 236 Score = 472 bits (1214), Expect = e-133 Identities = 236/236 (100%), Positives = 236/236 (100%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI Sbjct: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA Sbjct: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG Sbjct: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY Sbjct: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 >gi|5031715 regulator of G-protein signalling 19 interacting protein 1 isoform 1 [Homo sapiens] Length = 333 Score = 472 bits (1214), Expect = e-133 Identities = 236/236 (100%), Positives = 236/236 (100%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI Sbjct: 98 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 157 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA Sbjct: 158 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 217 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG Sbjct: 218 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 277 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 236 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY Sbjct: 278 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAKVGRY 333 >gi|41393579 PDZ domain protein GIPC2 [Homo sapiens] Length = 315 Score = 322 bits (826), Expect = 1e-88 Identities = 160/232 (68%), Positives = 191/232 (82%), Gaps = 2/232 (0%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 ++CTLNT K+DM++LLGGQ+GLEDFIFAHVKG KEV V+KSED+LGLTITDNG GYAFI Sbjct: 82 LYCTLNTPKIDMERLLGGQLGLEDFIFAHVKGIEKEVNVYKSEDSLGLTITDNGVGYAFI 141 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIK+G VID + I VGD IE+ING++++G RHY+VA+ LKEL + FT+KL EP+KA Sbjct: 142 KRIKDGGVIDSVKTICVGDHIESINGENIVGWRHYDVAKKLKELKKEELFTMKLIEPKKA 201 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 F+ I RS G+ SG ++G GR TLRLRS+GPATVE++PS + KAIEK+DD+LE YMG Sbjct: 202 FE-IELRSKAGK-SSGEKIGCGRATLRLRSKGPATVEEMPSETKAKAIEKIDDVLELYMG 259 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAK 232 IRD +LA TM E GKDK NPDE A ALDE LGDFAFPDEFVFDVWG IGDAK Sbjct: 260 IRDIDLATTMFEAGKDKVNPDEFAVALDETLGDFAFPDEFVFDVWGVIGDAK 311 >gi|18959204 GIPC PDZ domain containing family, member 3 [Homo sapiens] Length = 312 Score = 316 bits (809), Expect = 1e-86 Identities = 156/232 (67%), Positives = 187/232 (80%) Query: 1 MFCTLNTHKVDMDKLLGGQIGLEDFIFAHVKGQRKEVEVFKSEDALGLTITDNGAGYAFI 60 +FCTLN+HKVDM KLLGGQIGLEDFIFAHV+G+ KEVEV K+EDALGLTITDNGAGYAFI Sbjct: 77 LFCTLNSHKVDMQKLLGGQIGLEDFIFAHVRGETKEVEVTKTEDALGLTITDNGAGYAFI 136 Query: 61 KRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRKA 120 KRIKEGS+I+ I + VGD IEAIN S++GCRHYEVA++L+ELP+ + FTL+L +P++A Sbjct: 137 KRIKEGSIINRIEAVCVGDSIEAINDHSIVGCRHYEVAKMLRELPKSQPFTLRLVQPKRA 196 Query: 121 FDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEEKAIEKVDDLLESYMG 180 FDMI QRS + ++ +GR TLRLRS G ATVE+ PS FEE+A KVDDLLESYMG Sbjct: 197 FDMIGQRSRSSKCPVEAKVTSGRETLRLRSGGAATVEEAPSEFEEEASRKVDDLLESYMG 256 Query: 181 IRDTELAATMVELGKDKRNPDELAEALDERLGDFAFPDEFVFDVWGAIGDAK 232 IRD ELA+TMVE K + E A LD LG+FAFPDEFV +VW AIG+A+ Sbjct: 257 IRDPELASTMVETSKKTASAQEFARCLDSVLGEFAFPDEFVVEVWAAIGEAR 308 >gi|87196343 PDZ domain containing 2 [Homo sapiens] Length = 2839 Score = 50.8 bits (120), Expect = 1e-06 Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 5/76 (6%) Query: 37 VEVFKSEDALGLTITDN-----GAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLG 91 VEV K+ LGL++ G G IKR+ +G + +I GD I AING+ L+G Sbjct: 2751 VEVLKTSAGLGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVG 2810 Query: 92 CRHYEVARLLKELPRG 107 H++ ++K +P G Sbjct: 2811 LMHFDAWNIMKSVPEG 2826 Score = 36.6 bits (83), Expect = 0.019 Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 7/77 (9%) Query: 32 GQRKEVEVFKSEDALGLTITDNGAGYA------FIKRIKEGSVIDHIHLISVGDMIEAIN 85 G+ ++E+ K D LG+ ++ G G + ++KEG +S+GD + IN Sbjct: 330 GRIWKMELLKESDGLGIQVS-GGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVIN 388 Query: 86 GQSLLGCRHYEVARLLK 102 G L+G H E +L+ Sbjct: 389 GHLLVGLSHEEAVAILR 405 >gi|21536464 palmitoylated membrane protein 3 [Homo sapiens] Length = 585 Score = 41.6 bits (96), Expect = 6e-04 Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 3/93 (3%) Query: 35 KEVEVFKSEDALGLTIT-DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 93 K V + K+++ LG TI D +G + RI G D L+ VGD + +NG ++L R Sbjct: 136 KIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKR 195 Query: 94 HYEVARLLKELPRGRTFTLKLTEPRKAFDMISQ 126 E++++L + + TLK+ + D + + Sbjct: 196 PDEISQILAQ--SQGSITLKIIPATQEEDRLKE 226 >gi|148746189 multiple PDZ domain protein [Homo sapiens] Length = 2041 Score = 41.2 bits (95), Expect = 8e-04 Identities = 31/97 (31%), Positives = 48/97 (49%), Gaps = 19/97 (19%) Query: 31 KGQRKE---VEVFKSEDALGLTITDNGAGYA----------FIKRIKEGSVIDHIHLISV 77 KG+ E VE+ K+ LG+TI AGY F+K I + S ++H I + Sbjct: 369 KGEESETFDVELTKNVQGLGITI----AGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQI 424 Query: 78 GDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 114 GD I A++G +L G + + +L+ G+T L L Sbjct: 425 GDQIIAVDGTNLQGFTNQQAVEVLRH--TGQTVLLTL 459 Score = 41.2 bits (95), Expect = 8e-04 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 37 VEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYE 96 V F LG+++ + G+ FI+ + + H + GD + +NG +LLG H + Sbjct: 556 VSKFSENSGLGISL-EATVGHHFIRSVLPEGPVGHSGKLFSGDELLEVNGITLLGENHQD 614 Query: 97 VARLLKELP 105 V +LKELP Sbjct: 615 VVNILKELP 623 Score = 34.3 bits (77), Expect = 0.096 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 35 KEVEVFKSEDALGLTITDNGAGYAFIKR-IKEGSVIDHIHLISVGDMIEAINGQSLLGCR 93 + + + K +LG+T++ N G I R I G I I++GD I +IN +S + Sbjct: 1007 RTINIAKGNSSLGMTVSANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTISVT 1066 Query: 94 HYEVARLLK 102 + + +L+ Sbjct: 1067 NAQARAMLR 1075 Score = 33.5 bits (75), Expect = 0.16 Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 5/75 (6%) Query: 33 QRKEVEVFKSEDALGLTI-----TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQ 87 Q K + + + D LG +I + +G ++K + + GD I A+NGQ Sbjct: 1955 QCKSITLERGPDGLGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQ 2014 Query: 88 SLLGCRHYEVARLLK 102 SL G H E +LK Sbjct: 2015 SLEGVTHEEAVAILK 2029 Score = 32.0 bits (71), Expect = 0.48 Identities = 23/86 (26%), Positives = 35/86 (40%), Gaps = 3/86 (3%) Query: 30 VKGQRKEVEVFKSEDALGLTI---TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAING 86 + G +E+ K LGL+I +D G I + E + GD I +NG Sbjct: 1623 IPGCETTIEISKGRTGLGLSIVGGSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNG 1682 Query: 87 QSLLGCRHYEVARLLKELPRGRTFTL 112 L H E +L++ P+ TL Sbjct: 1683 IDLRKATHDEAINVLRQTPQRVRLTL 1708 Score = 30.4 bits (67), Expect = 1.4 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 9/66 (13%) Query: 33 QRKEVEVFK---------SEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 83 Q + VEVF+ +GL + G F++ I+EGSV + D I A Sbjct: 131 QGRHVEVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILA 190 Query: 84 INGQSL 89 INGQ+L Sbjct: 191 INGQAL 196 Score = 28.9 bits (63), Expect = 4.0 Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 41 KSEDALGLTITD--NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVA 98 K LGL+I N G F+ I +G + D + GD I +NG+ + VA Sbjct: 1731 KPGKGLGLSIVGKRNDTG-VFVSDIVKGGIADADGRLMQGDQILMVNGEDVRNATQEAVA 1789 Query: 99 RLLK 102 LLK Sbjct: 1790 ALLK 1793 Score = 28.5 bits (62), Expect = 5.3 Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 6/120 (5%) Query: 35 KEVEVFKSEDALGLTITDNGA-GYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 93 + +E+ K + LG+ I++ IK + E V + VGD I A++ + ++G Sbjct: 1482 QHLELPKDQGGLGIAISEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVG-- 1539 Query: 94 HYEVARLLKELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGP 153 Y + + + L + T+KLT + D + SA G SG + + + + +S P Sbjct: 1540 -YPIEKFISLLKTAK-MTVKLTIHAENPDSQAVPSAAG-AASGEKKNSSQSLMVPQSGSP 1596 >gi|27436957 membrane associated guanylate kinase, WW and PDZ domain containing 2 [Homo sapiens] Length = 1455 Score = 40.8 bits (94), Expect = 0.001 Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 2/55 (3%) Query: 60 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 114 I RI +GS D + VGD I A+NGQS++ H ++ +L+K+ G + TL++ Sbjct: 954 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKD--AGLSVTLRI 1006 Score = 35.4 bits (80), Expect = 0.043 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 4/74 (5%) Query: 39 VFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVA 98 + K G TI D+ G +R+K+ I + GD+I IN Q++ H EV Sbjct: 608 IVKGAQGFGFTIADSPTG----QRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVV 663 Query: 99 RLLKELPRGRTFTL 112 +LK+ P G +L Sbjct: 664 DILKDCPIGSETSL 677 Score = 30.0 bits (66), Expect = 1.8 Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 2/89 (2%) Query: 28 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 85 + +KG + KS G TI D + +K + + GD+I IN Sbjct: 418 SQLKGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYIN 477 Query: 86 GQSLLGCRHYEVARLLKELPRGRTFTLKL 114 +LG H +V +L + +P G++ L L Sbjct: 478 EVCVLGHTHADVVKLFQSVPIGQSVNLVL 506 >gi|187607085 ligand of numb-protein X 1 isoform a [Homo sapiens] Length = 728 Score = 40.8 bits (94), Expect = 0.001 Identities = 26/60 (43%), Positives = 34/60 (56%) Query: 53 NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTL 112 NG FIK I EG+ + I GD++ A+NG+S G H +ARLLKEL T T+ Sbjct: 661 NGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTI 720 >gi|187607071 ligand of numb-protein X 1 isoform b [Homo sapiens] Length = 632 Score = 40.8 bits (94), Expect = 0.001 Identities = 26/60 (43%), Positives = 34/60 (56%) Query: 53 NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTL 112 NG FIK I EG+ + I GD++ A+NG+S G H +ARLLKEL T T+ Sbjct: 565 NGNKPFFIKSIVEGTPAYNDGRIRCGDILLAVNGRSTSGMIHACLARLLKELKGRITLTI 624 >gi|66346708 membrane associated guanylate kinase, WW and PDZ domain containing 1 isoform b [Homo sapiens] Length = 1256 Score = 40.0 bits (92), Expect = 0.002 Identities = 23/55 (41%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Query: 60 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 114 I RI EGS D + VGD I A+NG S+ H ++ L+KE G T TL++ Sbjct: 1038 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKE--AGNTVTLRI 1090 Score = 33.9 bits (76), Expect = 0.13 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 2/76 (2%) Query: 37 VEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYE 96 V + K G TI D+ G +R+K+ + GD+I +N +++ H + Sbjct: 644 VHIVKGPMGFGFTIADSPGGGG--QRVKQIVDSPRCRGLKEGDLIVEVNKKNVQALTHNQ 701 Query: 97 VARLLKELPRGRTFTL 112 V +L E P+G TL Sbjct: 702 VVDMLVECPKGSEVTL 717 Score = 31.2 bits (69), Expect = 0.81 Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Query: 28 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 85 + +KG+ ++ KS G T+ D + IK + + GD+I ++N Sbjct: 464 SELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVN 523 Query: 86 GQSLLGCRHYEVARLLKELPRGRTFTLKL 114 +LG H +V ++ + +P G + L+L Sbjct: 524 DTCVLGHTHAQVVKIFQSIPIGASVDLEL 552 >gi|74272284 membrane associated guanylate kinase, WW and PDZ domain containing 1 isoform c [Homo sapiens] Length = 1462 Score = 40.0 bits (92), Expect = 0.002 Identities = 23/55 (41%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Query: 60 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 114 I RI EGS D + VGD I A+NG S+ H ++ L+KE G T TL++ Sbjct: 1009 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKE--AGNTVTLRI 1061 Score = 33.9 bits (76), Expect = 0.13 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 2/76 (2%) Query: 37 VEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYE 96 V + K G TI D+ G +R+K+ + GD+I +N +++ H + Sbjct: 644 VHIVKGPMGFGFTIADSPGGGG--QRVKQIVDSPRCRGLKEGDLIVEVNKKNVQALTHNQ 701 Query: 97 VARLLKELPRGRTFTL 112 V +L E P+G TL Sbjct: 702 VVDMLVECPKGSEVTL 717 Score = 31.2 bits (69), Expect = 0.81 Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Query: 28 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 85 + +KG+ ++ KS G T+ D + IK + + GD+I ++N Sbjct: 464 SELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVN 523 Query: 86 GQSLLGCRHYEVARLLKELPRGRTFTLKL 114 +LG H +V ++ + +P G + L+L Sbjct: 524 DTCVLGHTHAQVVKIFQSIPIGASVDLEL 552 Score = 28.1 bits (61), Expect = 6.9 Identities = 20/80 (25%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 59 FIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPR 118 ++ R+ E + + +GD I ING++ +H L+K GR L L Sbjct: 1148 YVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIELIKN--GGRRVRLFLKRGD 1205 Query: 119 KAFDMISQRSAGGRPGSGPQ 138 + S P +GPQ Sbjct: 1206 GSVPEYDPSSDRHGPATGPQ 1225 >gi|74272282 membrane associated guanylate kinase, WW and PDZ domain containing 1 isoform a [Homo sapiens] Length = 1287 Score = 40.0 bits (92), Expect = 0.002 Identities = 23/55 (41%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Query: 60 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKL 114 I RI EGS D + VGD I A+NG S+ H ++ L+KE G T TL++ Sbjct: 1037 IGRIIEGSPADRCGKLKVGDRILAVNGCSITNKSHSDIVNLIKE--AGNTVTLRI 1089 Score = 33.9 bits (76), Expect = 0.13 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 2/76 (2%) Query: 37 VEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYE 96 V + K G TI D+ G +R+K+ + GD+I +N +++ H + Sbjct: 644 VHIVKGPMGFGFTIADSPGGGG--QRVKQIVDSPRCRGLKEGDLIVEVNKKNVQALTHNQ 701 Query: 97 VARLLKELPRGRTFTL 112 V +L E P+G TL Sbjct: 702 VVDMLVECPKGSEVTL 717 Score = 31.2 bits (69), Expect = 0.81 Identities = 21/89 (23%), Positives = 41/89 (46%), Gaps = 2/89 (2%) Query: 28 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 85 + +KG+ ++ KS G T+ D + IK + + GD+I ++N Sbjct: 464 SELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVN 523 Query: 86 GQSLLGCRHYEVARLLKELPRGRTFTLKL 114 +LG H +V ++ + +P G + L+L Sbjct: 524 DTCVLGHTHAQVVKIFQSIPIGASVDLEL 552 >gi|218505835 membrane-associated guanylate kinase-related 3 isoform 1 [Homo sapiens] Length = 1481 Score = 40.0 bits (92), Expect = 0.002 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 12/101 (11%) Query: 60 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRK 119 I R+ EGS D + VGD I A+NGQS++ H + +L+K+ G T TL Sbjct: 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKD--AGVTVTL------- 932 Query: 120 AFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLP 160 +I++ G P SG L+ R G + +P Sbjct: 933 --TVIAEEEHHG-PPSGTNSARQSPALQHRPMGQSQANHIP 970 Score = 30.8 bits (68), Expect = 1.1 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 2/89 (2%) Query: 28 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 85 + +KG + KS G TI D + +K + + I+ GD+I IN Sbjct: 402 SQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDIN 461 Query: 86 GQSLLGCRHYEVARLLKELPRGRTFTLKL 114 G +LG H +V ++ + +P + L L Sbjct: 462 GNCVLGHTHADVVQMFQLVPVNQYVNLTL 490 >gi|155969695 membrane-associated guanylate kinase-related 3 isoform 2 [Homo sapiens] Length = 1125 Score = 40.0 bits (92), Expect = 0.002 Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 12/101 (11%) Query: 60 IKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLKLTEPRK 119 I R+ EGS D + VGD I A+NGQS++ H + +L+K+ G T TL Sbjct: 882 IGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKD--AGVTVTL------- 932 Query: 120 AFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLP 160 +I++ G P SG L+ R G + +P Sbjct: 933 --TVIAEEEHHG-PPSGTNSARQSPALQHRPMGQSQANHIP 970 Score = 30.8 bits (68), Expect = 1.1 Identities = 23/89 (25%), Positives = 39/89 (43%), Gaps = 2/89 (2%) Query: 28 AHVKGQRKEVEVFKSEDALGLTIT--DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAIN 85 + +KG + KS G TI D + +K + + I+ GD+I IN Sbjct: 402 SQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDIN 461 Query: 86 GQSLLGCRHYEVARLLKELPRGRTFTLKL 114 G +LG H +V ++ + +P + L L Sbjct: 462 GNCVLGHTHADVVQMFQLVPVNQYVNLTL 490 >gi|223890252 glutamate receptor interacting protein 1 [Homo sapiens] Length = 1076 Score = 39.7 bits (91), Expect = 0.002 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 37 VEVFKSEDA-LGLTITD--NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 93 VE+ K E LGLT++ + G + +++G + + VGD I+A+NG +L R Sbjct: 54 VELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFR 113 Query: 94 HYEVARLLKEL 104 H E+ LLK + Sbjct: 114 HDEIISLLKNV 124 Score = 33.9 bits (76), Expect = 0.13 Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 4/86 (4%) Query: 37 VEVFKSEDALGLTI--TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRH 94 VE+ + LG+TI T+ I + +G + + I +GD I AIN SL G Sbjct: 622 VELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPL 681 Query: 95 YEVARLLKELPRGRTFTLKLTEPRKA 120 E LL+ G T TLK+ + A Sbjct: 682 SEAIHLLQ--MAGETVTLKIKKQTDA 705 Score = 30.4 bits (67), Expect = 1.4 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Query: 37 VEVFKSEDA-LGLTITDN---GAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGC 92 VEV K+ A LG+ +T + I +IK S+ D + VGD I +I+G S+ C Sbjct: 253 VEVAKTPGASLGVALTTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYC 312 Query: 93 RHYEVARLL 101 E + L Sbjct: 313 TLAEATQFL 321 Score = 28.5 bits (62), Expect = 5.3 Identities = 20/74 (27%), Positives = 31/74 (41%), Gaps = 6/74 (8%) Query: 36 EVEVFKSEDALGLTITD------NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSL 89 EV + K + G I N + I ++ G D I GD + +++G L Sbjct: 152 EVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRL 211 Query: 90 LGCRHYEVARLLKE 103 LG H E +LK+ Sbjct: 212 LGTTHAEAMSILKQ 225 >gi|186972120 calcium/calmodulin-dependent serine protein kinase isoform 1 [Homo sapiens] Length = 921 Score = 39.7 bits (91), Expect = 0.002 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%) Query: 42 SEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLL 101 +++ +G+T+ N + + RI G +I + VGD I ING S+ ++ ++L Sbjct: 497 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 556 Query: 102 KELPRGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPS 161 +E+ RG + T K+ + +R + P G S +V DLPS Sbjct: 557 REM-RG-SITFKIVPSYRTQSSSCERDSPSTSRQSPANG--------HSSTNNSVSDLPS 606 Query: 162 AFEEK 166 + K Sbjct: 607 TTQPK 611 >gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein [Homo sapiens] Length = 1211 Score = 38.9 bits (89), Expect = 0.004 Identities = 24/71 (33%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 32 GQRKEVEVFKSEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLG 91 G R+ V V+K + G T+ G G +I+ + GS D+ L S GD I +NG + Sbjct: 275 GARRTVRVYKGNKSFGFTL--RGHGPVWIESVLPGSPADNAALKS-GDRILFLNGLDMRN 331 Query: 92 CRHYEVARLLK 102 C H +V +L+ Sbjct: 332 CSHDKVVSMLQ 342 Score = 30.8 bits (68), Expect = 1.1 Identities = 36/150 (24%), Positives = 55/150 (36%), Gaps = 26/150 (17%) Query: 54 GAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELPRGRTFTLK 113 G+G F+ + +GS H + GD I + G ++ G + RL + PR Sbjct: 23 GSGPCFVLEVAKGSSA-HAGGLRPGDQILEVEGLAVGGLSRERLVRLARRCPR------- 74 Query: 114 LTEPRKAFDMISQRSAGGRPGSGPQ--------------LGTGRGTLRLRSR-GPATVED 158 + ++ G PGSGP L GR LRL R P V Sbjct: 75 ---VPPSLGVLPAPDGGPGPGSGPAAPTTVLRAPRCGRGLALGRELLRLAGRKRPDAVHR 131 Query: 159 LPSAFEEKAIEKVDDLLESYMGIRDTELAA 188 ++ KVD++L ++ AA Sbjct: 132 ERRRKAQEFSRKVDEILGDQPTAKEQVFAA 161 >gi|122937249 glutamate receptor interacting protein 2 [Homo sapiens] Length = 1141 Score = 38.9 bits (89), Expect = 0.004 Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 37 VEVFKSEDA-LGLTITD--NGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 93 VE+ K E + LGLTI+ + G + ++ G + L+++GD I ++NG L R Sbjct: 146 VELIKKEGSTLGLTISGGTDKDGKPRVSNLRPGGLAARSDLLNIGDYIRSVNGIHLTRLR 205 Query: 94 HYEVARLLKEL 104 H E+ LLK + Sbjct: 206 HDEIITLLKNV 216 Score = 34.7 bits (78), Expect = 0.073 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Query: 37 VEVFKSE-DALGLTITDNGA---GYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGC 92 VE+ K+ ALG+++T I RIK SV+D + GD I +I+G S+ C Sbjct: 346 VEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHC 405 Query: 93 RHYEVARLLKEL 104 E +LL + Sbjct: 406 SLLEATKLLASI 417 Score = 32.3 bits (72), Expect = 0.36 Identities = 41/151 (27%), Positives = 59/151 (39%), Gaps = 29/151 (19%) Query: 37 VEVFKSEDALGLTI--TDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRH 94 VE+ + LG+TI T+ I + + + + I VGD I AIN SL G Sbjct: 755 VELKRYGGPLGITISGTEEPFDPIVISGLTKRGLAERTGAIHVGDRILAINNVSLKGRPL 814 Query: 95 YEVARLLKELPRGRTFTLKLTE-------PRKAFDMISQRSAGGRPGSGPQLGTGRGTLR 147 E LL+ G T TLK+ + PRK+ + A P + G Sbjct: 815 SEAIHLLQ--VAGETVTLKIKKQLDRPLLPRKSGSLSETSDADEDPADALKGG------- 865 Query: 148 LRSRGPATVEDLPSAFEEKAIEKVDDLLESY 178 LP+A A+ VD +ES+ Sbjct: 866 -----------LPAARFSPAVPSVDSAVESW 885 >gi|111154074 palmitoylated membrane protein 7 [Homo sapiens] Length = 576 Score = 38.5 bits (88), Expect = 0.005 Identities = 24/79 (30%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 35 KEVEVFKSEDALGLTIT-DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCR 93 K + + K+ + LG TI D G + RI G D LI VGD + +NG + R Sbjct: 138 KIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKR 197 Query: 94 HYEVARLLKELPRGRTFTL 112 E+ ++L + TF + Sbjct: 198 PEEIIQILAQSQGAITFKI 216 >gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit 9A [Homo sapiens] Length = 1098 Score = 38.1 bits (87), Expect = 0.007 Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 8/89 (8%) Query: 37 VEVFKSEDALGLTITDNGAGY--------AFIKRIKEGSVIDHIHLISVGDMIEAINGQS 88 VE+ K ED LG++I G G F+K + EG I V D I ++G S Sbjct: 505 VELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEVDGIS 564 Query: 89 LLGCRHYEVARLLKELPRGRTFTLKLTEP 117 L+G A +L+ F + +P Sbjct: 565 LVGVTQNFAATVLRNTKGNVRFVIGREKP 593 >gi|186700629 calcium/calmodulin-dependent serine protein kinase isoform 3 [Homo sapiens] Length = 897 Score = 37.7 bits (86), Expect = 0.009 Identities = 19/71 (26%), Positives = 37/71 (52%) Query: 42 SEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLL 101 +++ +G+T+ N + + RI G +I + VGD I ING S+ ++ ++L Sbjct: 491 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 550 Query: 102 KELPRGRTFTL 112 +E+ TF + Sbjct: 551 REMRGSITFKI 561 >gi|186700627 calcium/calmodulin-dependent serine protein kinase isoform 2 [Homo sapiens] Length = 898 Score = 37.7 bits (86), Expect = 0.009 Identities = 19/71 (26%), Positives = 37/71 (52%) Query: 42 SEDALGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLL 101 +++ +G+T+ N + + RI G +I + VGD I ING S+ ++ ++L Sbjct: 497 TDEPMGITLKMNELNHCIVARIMHGGMIHRQGTLHVGDEIREINGISVANQTVEQLQKML 556 Query: 102 KELPRGRTFTL 112 +E+ TF + Sbjct: 557 REMRGSITFKI 567 >gi|112382257 InaD-like [Homo sapiens] Length = 1801 Score = 37.7 bits (86), Expect = 0.009 Identities = 25/64 (39%), Positives = 31/64 (48%), Gaps = 5/64 (7%) Query: 44 DALGLTITDN-----GAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVA 98 DALG++I G FI I+ V + VGD I +INGQ L G H +V Sbjct: 1685 DALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSINGQPLDGLSHADVV 1744 Query: 99 RLLK 102 LLK Sbjct: 1745 NLLK 1748 Score = 33.9 bits (76), Expect = 0.13 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 46 LGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELP 105 LG+ + D+ G+ +I I G +D + L+ D + +NG L G E LKE+P Sbjct: 570 LGVEV-DSFDGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVP 628 Score = 32.3 bits (72), Expect = 0.36 Identities = 22/80 (27%), Positives = 31/80 (38%), Gaps = 3/80 (3%) Query: 30 VKGQRKEVEVFKSEDALGLTIT---DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAING 86 V GQ +E+ K LGL+I D I + E + GD I +NG Sbjct: 1431 VPGQEMIIEISKGRSGLGLSIVGGKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNG 1490 Query: 87 QSLLGCRHYEVARLLKELPR 106 L H E L++ P+ Sbjct: 1491 VDLRNSSHEEAITALRQTPQ 1510 Score = 31.6 bits (70), Expect = 0.62 Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 10/83 (12%) Query: 28 AHVKGQRKEVEVF------KSEDALGLTITD--NGAGYAFIKRIKEGSVIDHIHLISVGD 79 AH + + + +E+F K+ LGL+I NG+G FI I +G D + GD Sbjct: 1521 AHYRDE-ENLEIFPVDLQKKAGRGLGLSIVGKRNGSG-VFISDIVKGGAADLDGRLIQGD 1578 Query: 80 MIEAINGQSLLGCRHYEVARLLK 102 I ++NG+ + VA +LK Sbjct: 1579 QILSVNGEDMRNASQETVATILK 1601 Score = 29.6 bits (65), Expect = 2.4 Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 3/82 (3%) Query: 27 FAHVKGQRKEVEVFKSEDALGLTIT---DNGAGYAFIKRIKEGSVIDHIHLISVGDMIEA 83 +A + G+ +E+ K ++ LGL++ D F+ I + +GD + Sbjct: 1230 YADLPGELHIIELEKDKNGLGLSLAGNKDRSRMSIFVVGINPEGPAAADGRMRIGDELLE 1289 Query: 84 INGQSLLGCRHYEVARLLKELP 105 IN Q L G H + ++K P Sbjct: 1290 INNQILYGRSHQNASAIIKTAP 1311 >gi|154354983 regulating synaptic membrane exocytosis 2 isoform a [Homo sapiens] Length = 1349 Score = 37.0 bits (84), Expect = 0.015 Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 24/125 (19%) Query: 46 LGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELP 105 +G +T++G AFI ++K+GS+ D + + GD + NG+ L G EV ++ E Sbjct: 606 VGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILE-- 663 Query: 106 RGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEE 165 ++P +++ R G P R+ A +E S+FE Sbjct: 664 ---------SKPEPQVELVVSRPIGDIP-------------RIPDSTHAQLESSSSSFES 701 Query: 166 KAIEK 170 + +++ Sbjct: 702 QKMDR 706 >gi|154354981 regulating synaptic membrane exocytosis 2 isoform b [Homo sapiens] Length = 1163 Score = 37.0 bits (84), Expect = 0.015 Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 24/125 (19%) Query: 46 LGLTITDNGAGYAFIKRIKEGSVIDHIHLISVGDMIEAINGQSLLGCRHYEVARLLKELP 105 +G +T++G AFI ++K+GS+ D + + GD + NG+ L G EV ++ E Sbjct: 414 VGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNIILE-- 471 Query: 106 RGRTFTLKLTEPRKAFDMISQRSAGGRPGSGPQLGTGRGTLRLRSRGPATVEDLPSAFEE 165 ++P +++ R G P R+ A +E S+FE Sbjct: 472 ---------SKPEPQVELVVSRPIGDIP-------------RIPDSTHAQLESSSSSFES 509 Query: 166 KAIEK 170 + +++ Sbjct: 510 QKMDR 514 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.140 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,857,454 Number of Sequences: 37866 Number of extensions: 402679 Number of successful extensions: 1414 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 76 Number of HSP's successfully gapped in prelim test: 49 Number of HSP's that attempted gapping in prelim test: 1243 Number of HSP's gapped (non-prelim): 211 length of query: 236 length of database: 18,247,518 effective HSP length: 99 effective length of query: 137 effective length of database: 14,498,784 effective search space: 1986333408 effective search space used: 1986333408 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.