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Search of human proteins with 41406097
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41406097 dishevelled 3 [Homo sapiens]
(716 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41406097 dishevelled 3 [Homo sapiens] 1469 0.0
gi|4758216 dishevelled 2 [Homo sapiens] 946 0.0
gi|32479521 dishevelled 1 [Homo sapiens] 860 0.0
gi|39930479 DIX domain containing 1 isoform b [Homo sapiens] 72 1e-12
gi|83816971 DIX domain containing 1 isoform a [Homo sapiens] 72 1e-12
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i... 58 3e-08
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i... 58 3e-08
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is... 58 3e-08
gi|148833504 interleukin 16 isoform 2 [Homo sapiens] 57 6e-08
gi|87196343 PDZ domain containing 2 [Homo sapiens] 57 8e-08
gi|218156340 chapsyn-110 isoform 3 [Homo sapiens] 55 2e-07
gi|218156338 chapsyn-110 isoform 1 [Homo sapiens] 55 2e-07
gi|91199538 chapsyn-110 isoform 2 [Homo sapiens] 55 2e-07
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 54 4e-07
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 54 4e-07
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 54 4e-07
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 54 4e-07
gi|4557529 post-synaptic density protein 95 isoform 1 [Homo sapi... 54 5e-07
gi|192447426 post-synaptic density protein 95 isoform 2 [Homo sa... 54 5e-07
gi|119943106 synapse-associated protein 102 isoform a [Homo sapi... 54 5e-07
gi|24025688 ligand of numb-protein X 2 [Homo sapiens] 54 5e-07
gi|148746189 multiple PDZ domain protein [Homo sapiens] 53 9e-07
gi|112382257 InaD-like [Homo sapiens] 53 1e-06
gi|157388993 synaptojanin 2 binding protein [Homo sapiens] 53 1e-06
gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens] 52 1e-06
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 52 2e-06
gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens] 51 3e-06
gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens] 51 3e-06
gi|119120907 par-3 partitioning defective 3 homolog B isoform a ... 51 3e-06
gi|119120903 par-3 partitioning defective 3 homolog B isoform c ... 51 3e-06
>gi|41406097 dishevelled 3 [Homo sapiens]
Length = 716
Score = 1469 bits (3803), Expect = 0.0
Identities = 716/716 (100%), Positives = 716/716 (100%)
Query: 1 MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEI 60
MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEI
Sbjct: 1 MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPSYKFFFKSMDDDFGVVKEEI 60
Query: 61 SDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPH 120
SDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPH
Sbjct: 61 SDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSFHPH 120
Query: 121 AGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLM 180
AGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLM
Sbjct: 121 AGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLM 180
Query: 181 SSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD 240
SSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD
Sbjct: 181 SSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD 240
Query: 241 STMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLL 300
STMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLL
Sbjct: 241 STMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLL 300
Query: 301 QVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAA 360
QVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAA
Sbjct: 301 QVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPIDPAA 360
Query: 361 WVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMA 420
WVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMA
Sbjct: 361 WVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIVKAMA 420
Query: 421 SPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHT 480
SPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHT
Sbjct: 421 SPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGFIRHT 480
Query: 481 VNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQY 540
VNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQY
Sbjct: 481 VNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPMAFPYQY 540
Query: 541 PPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGG 600
PPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGG
Sbjct: 541 PPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAGDSKSGG 600
Query: 601 SGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPP 660
SGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPP
Sbjct: 601 SGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPP 660
Query: 661 LYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM 716
LYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM
Sbjct: 661 LYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVDVM 716
>gi|4758216 dishevelled 2 [Homo sapiens]
Length = 736
Score = 946 bits (2446), Expect = 0.0
Identities = 515/743 (69%), Positives = 588/743 (79%), Gaps = 44/743 (5%)
Query: 1 MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRPS-YKFFFKSMDDDFGVVKEE 59
+GETK+IYHLD +ETPYLVK+P+PAER+TL DFK VLQRP+ K+FFKSMD DFGVVKEE
Sbjct: 11 VGETKVIYHLDEEETPYLVKIPVPAERITLGDFKSVLQRPAGAKYFFKSMDQDFGVVKEE 70
Query: 60 ISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPM--------ERTGGIGD 111
ISDDNA+LPCFNGRVVSWLVS++ P+ AP + +EL PP ERT GIGD
Sbjct: 71 ISDDNARLPCFNGRVVSWLVSSDNPQPEMAPPVHEPRAELAPPAPPLPPLPPERTSGIGD 130
Query: 112 SRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGER-RREP 170
SRPPSFHP+ S ENL+ +TET+S+VS +RERPRRRD EH + T R R
Sbjct: 131 SRPPSFHPNVSS-SHENLEPETETESVVSLRRERPRRRDSSEHGAGGHRTGGPSRLERHL 189
Query: 171 GGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIE 230
GY+SSSTLM+SELE+TS DSDE+D+ SRFSSSTEQSSASRL++RH RRRRKQ+ R+E
Sbjct: 190 AGYESSSTLMTSELESTSLGDSDEEDTMSRFSSSTEQSSASRLLKRH-RRRRKQRPPRLE 248
Query: 231 RSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAAD 290
R+SSFSS+TDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAAD
Sbjct: 249 RTSSFSSVTDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAAD 308
Query: 291 GRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRS 350
GRIEPGDMLLQVN++NFENMSNDDAVRVLR+IVHKPGPI LTVAKCWDPSP+ FTLPR+
Sbjct: 309 GRIEPGDMLLQVNDMNFENMSNDDAVRVLRDIVHKPGPIVLTVAKCWDPSPQAYFTLPRN 368
Query: 351 EPIRPIDPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHS 410
EPI+PIDPAAWVSH+AA+TGTFPAY S S+STITS SS+PD + LS+H+
Sbjct: 369 EPIQPIDPAAWVSHSAALTGTFPAYPGSSSMSTITS-----GSSLPD--GCEGRGLSVHT 421
Query: 411 DMAAIVKAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASN 470
DMA++ KAMA+PESGLEVRDRMWLKITIPNAF+GSDVVDWLYH+VEGF +RREARKYAS
Sbjct: 422 DMASVTKAMAAPESGLEVRDRMWLKITIPNAFLGSDVVDWLYHHVEGFPERREARKYASG 481
Query: 471 LLKAGFIRHTVNKITFSEQCYYIFGDLCGN----MANLSLHDHDGSSGASDQDTLAPLPH 526
LLKAG IRHTVNKITFSEQCYY+FGDL G + NLSL+D+DGSSGASDQDTLAPL
Sbjct: 482 LLKAGLIRHTVNKITFSEQCYYVFGDLSGGCESYLVNLSLNDNDGSSGASDQDTLAPL-- 539
Query: 527 PGAAPWPM--AFPYQYPPPPHPYNPH-PGFPEL-GYSYGGGSASSQHSEGSRSSGSNRS- 581
PGA PWP+ F YQY P PHPY+P P + EL Y+YGGGSASSQHSEGSRSSGS RS
Sbjct: 540 PGATPWPLLPTFSYQY-PAPHPYSPQPPPYHELSSYTYGGGSASSQHSEGSRSSGSTRSD 598
Query: 582 -GSDRRKEKDPKAGDSKSGGSGSESDHTTR-SSLRGPRERAPSERSGPAASEHSHRSHHS 639
G+ R + +A +SKS GSGSES+ ++R SLR E + + GP S R
Sbjct: 599 GGAGRTGRPEERAPESKS-GSGSESEPSSRGGSLRRGGEASGTSDGGPPPS----RGSTG 653
Query: 640 LASSLRSH-HTHPSYGPPGVPPLYGPPM-LMMPPP----PAAMGPPGAPPGRDLASVPPE 693
A +LR+H HP PPG+ Y P M +MMPPP P A+ PPGAPP RDL SVPPE
Sbjct: 654 GAPNLRAHPGLHPYGPPPGMALPYNPMMVVMMPPPPPPVPPAVQPPGAPPVRDLGSVPPE 713
Query: 694 LTASRQSFRMAMGNPSEFFVDVM 716
LTASRQSF MAMGNPSEFFVDVM
Sbjct: 714 LTASRQSFHMAMGNPSEFFVDVM 736
>gi|32479521 dishevelled 1 [Homo sapiens]
Length = 670
Score = 860 bits (2222), Expect = 0.0
Identities = 459/722 (63%), Positives = 545/722 (75%), Gaps = 58/722 (8%)
Query: 1 MGETKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQ-RP--SYKFFFKSMDDDFGVVK 57
M ETKIIYH+D +ETPYLVKLP+ ERVTLADFK VL RP +YKFFFKSMD DFGVVK
Sbjct: 1 MAETKIIYHMDEEETPYLVKLPVAPERVTLADFKNVLSNRPVHAYKFFFKSMDQDFGVVK 60
Query: 58 EEISDDNAKLPCFNGRVVSWLVSAEGSHPDPAPFCADNPSELPPPMERTGGIGDSRPPSF 117
EEI DDNAKLPCFNGRVVSWLV AEG+H D D+ ++LPPP+ERTGGIGDSRPPSF
Sbjct: 61 EEIFDDNAKLPCFNGRVVSWLVLAEGAHSDAGSQGTDSHTDLPPPLERTGGIGDSRPPSF 120
Query: 118 HPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNGTAKGERRREPG-GYDSS 176
HP+ S++ +DN+T T+S+VS +RER RRR+ E A R NG +G+RRR+ G DS+
Sbjct: 121 HPNVAS-SRDGMDNETGTESMVSHRRERARRRNR-EEAARTNGHPRGDRRRDVGLPPDSA 178
Query: 177 STLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFS 236
ST +SSELE++SF DSDED STSR SSSTEQS++SRL+R+HKRRRRKQ++ + +R+SSFS
Sbjct: 179 STALSSELESSSFVDSDEDGSTSRLSSSTEQSTSSRLIRKHKRRRRKQRLRQADRASSFS 238
Query: 237 SITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPG 296
SITDSTMSLNI+TVTLNME+++FLGISIVGQSN+RGDGGIYIGSIMKGGAVAADGRIEPG
Sbjct: 239 SITDSTMSLNIVTVTLNMERHHFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPG 298
Query: 297 DMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPRGCFTLPRSEPIRPI 356
DMLLQVN++NFENMSNDDAVRVLREIV + GPI+LTVAKCWDP+PR FT+PR++P+RPI
Sbjct: 299 DMLLQVNDVNFENMSNDDAVRVLREIVSQTGPISLTVAKCWDPTPRSYFTVPRADPVRPI 358
Query: 357 DPAAWVSHTAAMTGTFPAYGMSPSLSTITSTSSSITSSIPDTERLDDFHLSIHSDMAAIV 416
DPAAW+SHTAA+TG P Y L++ L++ SDM+A+V
Sbjct: 359 DPAAWLSHTAALTGALPRY------------------------ELEEAPLTVKSDMSAVV 394
Query: 417 KAMASPESGLEVRDRMWLKITIPNAFIGSDVVDWLYHNVEGFTDRREARKYASNLLKAGF 476
+ M P+SGLE+RDRMWLKITI NA IG+DVVDWLY +VEGF +RREARKYAS+LLK GF
Sbjct: 395 RVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLYTHVEGFKERREARKYASSLLKHGF 454
Query: 477 IRHTVNKITFSEQCYYIFGDLCGNMANLSLHDHDGSSGASDQDTLAPLPHPGAAPWPM-- 534
+RHTVNKITFSEQCYY+FGDLC N+A L+L + GSSG SDQDTLAPLPHP AAPWP+
Sbjct: 455 LRHTVNKITFSEQCYYVFGDLCSNLATLNL--NSGSSGTSDQDTLAPLPHP-AAPWPLGQ 511
Query: 535 AFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRSGSDRRKEKDPKAG 594
+PYQYP PP P P P + + G+SYG GS SQ SEGS+SSGS RS S R ++ +
Sbjct: 512 GYPYQYPGPP-PCFP-PAYQDPGFSYGSGSTGSQQSEGSKSSGSTRS-SRRAPGREKERR 568
Query: 595 DSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTHPSYG 654
+ +GGSGSESDHT S + S R PA S S AS+
Sbjct: 569 AAGAGGSGSESDHTAPSGV------GSSWRERPAGQLSRGSSPRSQASAT---------- 612
Query: 655 PPGVPPLYGPPMLMMPPPPAAMGPPGAPPGRDLASVPPELTASRQSFRMAMGNPSEFFVD 714
PG+P PP GPPG PP R+LA+VPPELT SRQSF+ AMGNP EFFVD
Sbjct: 613 APGLP----PPHPTTKAYTVVGGPPGGPPVRELAAVPPELTGSRQSFQKAMGNPCEFFVD 668
Query: 715 VM 716
+M
Sbjct: 669 IM 670
>gi|39930479 DIX domain containing 1 isoform b [Homo sapiens]
Length = 472
Score = 72.4 bits (176), Expect = 1e-12
Identities = 32/83 (38%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Query: 4 TKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRP-SYKFFFKSMDDDFGVVKEEISD 62
TK++Y D TP++V +P E VTL DFK + R ++++ FK++D +FG VKEEI
Sbjct: 390 TKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFH 449
Query: 63 DNAKLPCFNGRVVSWLVSAEGSH 85
D+ +P + G++V+W+ G +
Sbjct: 450 DDDAIPGWEGKIVAWVEEDHGEN 472
>gi|83816971 DIX domain containing 1 isoform a [Homo sapiens]
Length = 683
Score = 72.4 bits (176), Expect = 1e-12
Identities = 32/83 (38%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Query: 4 TKIIYHLDGQETPYLVKLPLPAERVTLADFKGVLQRP-SYKFFFKSMDDDFGVVKEEISD 62
TK++Y D TP++V +P E VTL DFK + R ++++ FK++D +FG VKEEI
Sbjct: 601 TKVLYFTDRSLTPFMVNIPKRLEEVTLKDFKAAIDREGNHRYHFKALDPEFGTVKEEIFH 660
Query: 63 DNAKLPCFNGRVVSWLVSAEGSH 85
D+ +P + G++V+W+ G +
Sbjct: 661 DDDAIPGWEGKIVAWVEEDHGEN 683
>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
isoform 3 [Homo sapiens]
Length = 2294
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/230 (25%), Positives = 98/230 (42%), Gaps = 36/230 (15%)
Query: 116 SFHPHAG--GGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNG---TAKGERRREP 170
SF P G GS + D+ TE+ SL +Q +NG + G++ +
Sbjct: 1041 SFGPSGGLREGSLSSQDSRTESASLSQSQ---------------VNGFFASHLGDQTWQE 1085
Query: 171 GGYDSSS-TLMSSELETTSFFDSDED-----------DSTSRFSSSTEQSSASRLMRRHK 218
+ S S +++S E +F DS++ D + R S ++++ S
Sbjct: 1086 SQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQT 1145
Query: 219 RRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNER-GDGGIY 277
++ +F + + S I + N LGIS+ G N GGIY
Sbjct: 1146 PKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIY 1205
Query: 278 IGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR---EIVH 324
+ +++ GA +DGRI GD +L VN ++ E ++ AV LR ++VH
Sbjct: 1206 VKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVH 1255
Score = 53.9 bits (128), Expect = 5e-07
Identities = 35/123 (28%), Positives = 63/123 (51%), Gaps = 8/123 (6%)
Query: 214 MRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVG-QSNERG 272
MR + + Q + + + S S + ++L V L + LG I+G + R
Sbjct: 871 MRARQSNQDAQDIDVLHKRWSIVSSPEREITL----VNLKKDAKYGLGFQIIGGEKMGRL 926
Query: 273 DGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLT 332
D GI+I S+ GG DG ++PGD L+ VN ++ E +S+ A+ +L+ + P +TL
Sbjct: 927 DLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQ---NAPEDVTLV 983
Query: 333 VAK 335
+++
Sbjct: 984 ISQ 986
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 202 SSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLG 261
S S SS + H +Q+ ++ + + D + + ++ + EK + LG
Sbjct: 1551 SESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS-LG 1609
Query: 262 ISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
++ + N+R G Y+ +++ A +DGR++PGD L++VN+ + NM++ DAV +LR
Sbjct: 1610 FTVT-KGNQRI--GCYVHDVIQDPA-KSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1664
Score = 35.0 bits (79), Expect = 0.24
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 566 SSQHS--EGSRSSGSNRSGSDRRKE-KDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPS 622
SSQ S E S SS N +K+ K P DS S SGS D AP+
Sbjct: 1427 SSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT---------APA 1477
Query: 623 ERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPP------PAAM 676
S S H++ ++ S +SHH P + ++ P + P P+ +
Sbjct: 1478 NISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPL 1537
Query: 677 GPPGAPPGR 685
PP PG+
Sbjct: 1538 -PPDMAPGQ 1545
Score = 32.3 bits (72), Expect = 1.6
Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 9/101 (8%)
Query: 224 QKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSN---ERGDGGIY-IG 279
+KV + + +S +T+ N V L + + LG S + N E+ + I +
Sbjct: 1289 EKVKKTTQVKDYSFVTEE----NTFEVKL-FKNSSGLGFSFSREDNLIPEQINASIVRVK 1343
Query: 280 SIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
+ G A G+I+ GD++L+VN + + +S + + LR
Sbjct: 1344 KLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALR 1384
>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
isoform 1 [Homo sapiens]
Length = 2485
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/230 (25%), Positives = 98/230 (42%), Gaps = 36/230 (15%)
Query: 116 SFHPHAG--GGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNG---TAKGERRREP 170
SF P G GS + D+ TE+ SL +Q +NG + G++ +
Sbjct: 1232 SFGPSGGLREGSLSSQDSRTESASLSQSQ---------------VNGFFASHLGDQTWQE 1276
Query: 171 GGYDSSS-TLMSSELETTSFFDSDED-----------DSTSRFSSSTEQSSASRLMRRHK 218
+ S S +++S E +F DS++ D + R S ++++ S
Sbjct: 1277 SQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQT 1336
Query: 219 RRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNER-GDGGIY 277
++ +F + + S I + N LGIS+ G N GGIY
Sbjct: 1337 PKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIY 1396
Query: 278 IGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR---EIVH 324
+ +++ GA +DGRI GD +L VN ++ E ++ AV LR ++VH
Sbjct: 1397 VKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVH 1446
Score = 54.3 bits (129), Expect = 4e-07
Identities = 59/244 (24%), Positives = 93/244 (38%), Gaps = 23/244 (9%)
Query: 94 DNPSELPPPMERTGGIGDSRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPE 153
D S P E + D S +PH + + N V+ +P +
Sbjct: 955 DKASWEEKPREMSKSYHDLSQASLYPHR----KNVIVNMEPPPQTVAELVGKPSHQMSRS 1010
Query: 154 HATRLNGTAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSR-FSSSTEQSSASR 212
A L G K + + S E +++S D + SS SS
Sbjct: 1011 DAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVP 1070
Query: 213 LMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVG-QSNER 271
L +R VS ER I V L + LG I+G + R
Sbjct: 1071 LKENDVLHKRWSIVSSPERE--------------ITLVNLKKDAKYGLGFQIIGGEKMGR 1116
Query: 272 GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITL 331
D GI+I S+ GG DG ++PGD L+ VN ++ E +S+ A+ +L+ + P +TL
Sbjct: 1117 LDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQ---NAPEDVTL 1173
Query: 332 TVAK 335
+++
Sbjct: 1174 VISQ 1177
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 202 SSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLG 261
S S SS + H +Q+ ++ + + D + + ++ + EK + LG
Sbjct: 1742 SESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS-LG 1800
Query: 262 ISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
++ + N+R G Y+ +++ A +DGR++PGD L++VN+ + NM++ DAV +LR
Sbjct: 1801 FTVT-KGNQRI--GCYVHDVIQDPA-KSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1855
Score = 35.0 bits (79), Expect = 0.24
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 566 SSQHS--EGSRSSGSNRSGSDRRKE-KDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPS 622
SSQ S E S SS N +K+ K P DS S SGS D AP+
Sbjct: 1618 SSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT---------APA 1668
Query: 623 ERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPP------PAAM 676
S S H++ ++ S +SHH P + ++ P + P P+ +
Sbjct: 1669 NISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPL 1728
Query: 677 GPPGAPPGR 685
PP PG+
Sbjct: 1729 -PPDMAPGQ 1736
Score = 32.3 bits (72), Expect = 1.6
Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 9/101 (8%)
Query: 224 QKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSN---ERGDGGIY-IG 279
+KV + + +S +T+ N V L + + LG S + N E+ + I +
Sbjct: 1480 EKVKKTTQVKDYSFVTEE----NTFEVKL-FKNSSGLGFSFSREDNLIPEQINASIVRVK 1534
Query: 280 SIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
+ G A G+I+ GD++L+VN + + +S + + LR
Sbjct: 1535 KLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALR 1575
>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
2 [Homo sapiens]
Length = 2466
Score = 57.8 bits (138), Expect = 3e-08
Identities = 58/230 (25%), Positives = 98/230 (42%), Gaps = 36/230 (15%)
Query: 116 SFHPHAG--GGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNG---TAKGERRREP 170
SF P G GS + D+ TE+ SL +Q +NG + G++ +
Sbjct: 1213 SFGPSGGLREGSLSSQDSRTESASLSQSQ---------------VNGFFASHLGDQTWQE 1257
Query: 171 GGYDSSS-TLMSSELETTSFFDSDED-----------DSTSRFSSSTEQSSASRLMRRHK 218
+ S S +++S E +F DS++ D + R S ++++ S
Sbjct: 1258 SQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQT 1317
Query: 219 RRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNER-GDGGIY 277
++ +F + + S I + N LGIS+ G N GGIY
Sbjct: 1318 PKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIY 1377
Query: 278 IGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR---EIVH 324
+ +++ GA +DGRI GD +L VN ++ E ++ AV LR ++VH
Sbjct: 1378 VKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVH 1427
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/150 (27%), Positives = 71/150 (47%), Gaps = 14/150 (9%)
Query: 196 DSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITD---------STMSLN 246
+S + + S + L R +RR+ + S IE + + D S+
Sbjct: 1013 ESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQ-AYVLDVLHKRWSIVSSPERE 1071
Query: 247 IITVTLNMEKYNFLGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEI 305
I V L + LG I+G + R D GI+I S+ GG DG ++PGD L+ VN +
Sbjct: 1072 ITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISVNSV 1131
Query: 306 NFENMSNDDAVRVLREIVHKPGPITLTVAK 335
+ E +S+ A+ +L+ + P +TL +++
Sbjct: 1132 SLEGVSHHAAIEILQ---NAPEDVTLVISQ 1158
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 202 SSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLG 261
S S SS + H +Q+ ++ + + D + + ++ + EK + LG
Sbjct: 1723 SESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS-LG 1781
Query: 262 ISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
++ + N+R G Y+ +++ A +DGR++PGD L++VN+ + NM++ DAV +LR
Sbjct: 1782 FTVT-KGNQRI--GCYVHDVIQDPA-KSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1836
Score = 35.0 bits (79), Expect = 0.24
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 566 SSQHS--EGSRSSGSNRSGSDRRKE-KDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPS 622
SSQ S E S SS N +K+ K P DS S SGS D AP+
Sbjct: 1599 SSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT---------APA 1649
Query: 623 ERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPP------PAAM 676
S S H++ ++ S +SHH P + ++ P + P P+ +
Sbjct: 1650 NISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPL 1709
Query: 677 GPPGAPPGR 685
PP PG+
Sbjct: 1710 -PPDMAPGQ 1717
Score = 32.3 bits (72), Expect = 1.6
Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 9/101 (8%)
Query: 224 QKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSN---ERGDGGIY-IG 279
+KV + + +S +T+ N V L + + LG S + N E+ + I +
Sbjct: 1461 EKVKKTTQVKDYSFVTEE----NTFEVKL-FKNSSGLGFSFSREDNLIPEQINASIVRVK 1515
Query: 280 SIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
+ G A G+I+ GD++L+VN + + +S + + LR
Sbjct: 1516 KLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALR 1556
>gi|148833504 interleukin 16 isoform 2 [Homo sapiens]
Length = 1332
Score = 57.0 bits (136), Expect = 6e-08
Identities = 41/122 (33%), Positives = 63/122 (51%), Gaps = 6/122 (4%)
Query: 227 SRIERSSSFSSITDSTMSLN---IITVTLNMEKYNFLGISIVGQSNE-RGDGGIYIGSIM 282
SR RS S + + + L I + L + LG SIVG + G GIY+ +I
Sbjct: 191 SRPTRSLSTAQLVQPSGGLQASVISNIVLMKGQAKGLGFSIVGGKDSIYGPIGIYVKTIF 250
Query: 283 KGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPR 342
GGA AADGR++ GD +L++N + +++ DA++ ++ K G +TLTV P
Sbjct: 251 AGGAAAADGRLQEGDEILELNGESMAGLTHQDALQKFKQA--KKGLLTLTVRTRLTAPPS 308
Query: 343 GC 344
C
Sbjct: 309 LC 310
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 227 SRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVG-QSNERGDGGIYIGSIMKGG 285
S S++ +ST + TVTL LG S+ G + + GD + I I KG
Sbjct: 1212 SAASASAASDVSVESTAEATVCTVTLEKMSAG-LGFSLEGGKGSLHGDKPLTINRIFKGA 1270
Query: 286 AVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAK 335
A ++PGD +LQ+ + ++ +A +++ + GP+T+ + +
Sbjct: 1271 ASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKAL--PDGPVTIVIRR 1318
Score = 38.5 bits (88), Expect = 0.022
Identities = 41/179 (22%), Positives = 81/179 (45%), Gaps = 15/179 (8%)
Query: 146 PRRRDGPEHATRLNGTAKGERRREPGGYDSSSTLMSSELE--TTSFFDSDEDDSTSRFSS 203
P+ P ++ + A G E D+ +L SEL T ++ EDD S
Sbjct: 1018 PKEGASPTSSSNEDSAANGSA--ETSALDTGFSLNLSELREYTEGLTEAKEDDDGDHSSL 1075
Query: 204 STEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVT-LNMEKYNFLGI 262
+ QS S L+ + ++ ++V ++ ++ L+ I VT L+ E+ LG
Sbjct: 1076 QSGQSVIS-LLSSEELKKLIEEVKVLDEAT--------LKQLDGIHVTILHKEEGAGLGF 1126
Query: 263 SIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLRE 321
S+ G ++ I + + G + +G I+ G+ +L +N + + ++ DA+ +LR+
Sbjct: 1127 SLAGGADLENKV-ITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQ 1184
Score = 36.6 bits (83), Expect = 0.083
Identities = 21/93 (22%), Positives = 46/93 (49%), Gaps = 2/93 (2%)
Query: 247 IITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEIN 306
++ V+L E LGI + + GI++ ++ G DGR+ GD ++++++
Sbjct: 353 MVEVSLQKEAGVGLGIGLCSVPYFQCISGIFVHTLSPGSVAHLDGRLRCGDEIVEISDSP 412
Query: 307 FENMSNDDAVRVLREIVHKPGPITLTVAKCWDP 339
++ ++ +L PGP+ + V++ DP
Sbjct: 413 VHCLTLNEVYTILSHC--DPGPVPIIVSRHPDP 443
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 56.6 bits (135), Expect = 8e-08
Identities = 46/143 (32%), Positives = 72/143 (50%), Gaps = 10/143 (6%)
Query: 206 EQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIV 265
+ SSAS+ K+ R +++E S + I S +S+ + L EK LG SI
Sbjct: 549 DSSSASQEYHIVKKSTRSLSTTQVE--SPWRLIRPSVISI----IGLYKEKGKGLGFSIA 602
Query: 266 GQSN-ERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVH 324
G + RG GI++ +I G+ A DGR++ GD +L VN I + ++ +A+ ++I
Sbjct: 603 GGRDCIRGQMGIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQI-- 660
Query: 325 KPGPITLTV-AKCWDPSPRGCFT 346
+ G LTV K PS C T
Sbjct: 661 RSGLFVLTVRTKLVSPSLTPCST 683
Score = 48.9 bits (115), Expect = 2e-05
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 232 SSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADG 291
SSS T ++ VTLN E LGI + E GIYI S+ G +
Sbjct: 711 SSSLGRKTPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMES 770
Query: 292 RIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKCWDPSPR 342
+ GD +L+VN +N + + +L + PGP+ L + + P+P+
Sbjct: 771 NLSRGDQILEVNSVNVRHAALSKVHAILSKC--PPGPVRLVIGR--HPNPK 817
Score = 43.5 bits (101), Expect = 7e-04
Identities = 26/77 (33%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 260 LGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRV 318
LG+S+ G +S+ GDG + I + KGGA G IE GD +L +N + + DA +
Sbjct: 2760 LGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMHFDAWNI 2819
Query: 319 LREIVHKPGPITLTVAK 335
++ + GP+ L + K
Sbjct: 2820 MKSV--PEGPVQLLIRK 2834
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/76 (34%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 260 LGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRV 318
LGI + G + ++R I + + +GGA DGR+ GD LL +N +S+++AV +
Sbjct: 344 LGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAI 403
Query: 319 LREIVHKPGPITLTVA 334
LR G + L VA
Sbjct: 404 LRSAT---GMVQLVVA 416
>gi|218156340 chapsyn-110 isoform 3 [Homo sapiens]
Length = 749
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 10/83 (12%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI VG + GD IY+ I+ GGA DGR++ GD LL VN + E +++++AV
Sbjct: 152 LGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAV 211
Query: 317 RVLR---EIVH----KPGPITLT 332
+L+ E+V+ KP I +T
Sbjct: 212 AILKNTSEVVYLKVGKPTTIYMT 234
Score = 50.8 bits (120), Expect = 4e-06
Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 3/65 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G ++ D GI+I I+ GGA A DGR+ D +L+VNE++ +S+ AV
Sbjct: 57 LGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAV 116
Query: 317 RVLRE 321
L+E
Sbjct: 117 EALKE 121
Score = 40.0 bits (92), Expect = 0.008
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I++ I+ GG G ++ GD +L VN I+ S++ A L
Sbjct: 328 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAAL 384
Query: 320 R 320
+
Sbjct: 385 K 385
>gi|218156338 chapsyn-110 isoform 1 [Homo sapiens]
Length = 975
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 10/83 (12%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI VG + GD IY+ I+ GGA DGR++ GD LL VN + E +++++AV
Sbjct: 308 LGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAV 367
Query: 317 RVLR---EIVH----KPGPITLT 332
+L+ E+V+ KP I +T
Sbjct: 368 AILKNTSEVVYLKVGKPTTIYMT 390
Score = 50.8 bits (120), Expect = 4e-06
Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 3/65 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G ++ D GI+I I+ GGA A DGR+ D +L+VNE++ +S+ AV
Sbjct: 213 LGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAV 272
Query: 317 RVLRE 321
L+E
Sbjct: 273 EALKE 277
Score = 40.0 bits (92), Expect = 0.008
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I++ I+ GG G ++ GD +L VN I+ S++ A L
Sbjct: 536 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAAL 592
Query: 320 R 320
+
Sbjct: 593 K 593
>gi|91199538 chapsyn-110 isoform 2 [Homo sapiens]
Length = 870
Score = 55.1 bits (131), Expect = 2e-07
Identities = 33/83 (39%), Positives = 49/83 (59%), Gaps = 10/83 (12%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI VG + GD IY+ I+ GGA DGR++ GD LL VN + E +++++AV
Sbjct: 203 LGFSIAGGVGNQHIPGDNSIYVTKIIDGGAAQKDGRLQVGDRLLMVNNYSLEEVTHEEAV 262
Query: 317 RVLR---EIVH----KPGPITLT 332
+L+ E+V+ KP I +T
Sbjct: 263 AILKNTSEVVYLKVGKPTTIYMT 285
Score = 50.8 bits (120), Expect = 4e-06
Identities = 27/65 (41%), Positives = 39/65 (60%), Gaps = 3/65 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G ++ D GI+I I+ GGA A DGR+ D +L+VNE++ +S+ AV
Sbjct: 108 LGFSIAGGTDNPHIGDDPGIFITKIIPGGAAAEDGRLRVNDCILRVNEVDVSEVSHSKAV 167
Query: 317 RVLRE 321
L+E
Sbjct: 168 EALKE 172
Score = 40.0 bits (92), Expect = 0.008
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I++ I+ GG G ++ GD +L VN I+ S++ A L
Sbjct: 431 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELQRGDQILSVNGIDLRGASHEQAAAAL 487
Query: 320 R 320
+
Sbjct: 488 K 488
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 54.3 bits (129), Expect = 4e-07
Identities = 36/90 (40%), Positives = 50/90 (55%), Gaps = 6/90 (6%)
Query: 247 IITVTLNMEKYNFLGISIVGQSNERGDG-GIYIGSIMKGGAVAADGRIEPGDMLLQVNEI 305
IITVTL +K N +G+SIV D GIY+ S++KGGA DGR+ GD LL V+
Sbjct: 1006 IITVTL--KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGR 1063
Query: 306 NFENMSNDDAVRVLREIVHKPGPITLTVAK 335
+ +S + A ++ +TL VAK
Sbjct: 1064 SLVGLSQERAAELM---TRTSSVVTLEVAK 1090
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 54.3 bits (129), Expect = 4e-07
Identities = 36/90 (40%), Positives = 50/90 (55%), Gaps = 6/90 (6%)
Query: 247 IITVTLNMEKYNFLGISIVGQSNERGDG-GIYIGSIMKGGAVAADGRIEPGDMLLQVNEI 305
IITVTL +K N +G+SIV D GIY+ S++KGGA DGR+ GD LL V+
Sbjct: 1007 IITVTL--KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGR 1064
Query: 306 NFENMSNDDAVRVLREIVHKPGPITLTVAK 335
+ +S + A ++ +TL VAK
Sbjct: 1065 SLVGLSQERAAELM---TRTSSVVTLEVAK 1091
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 54.3 bits (129), Expect = 4e-07
Identities = 36/90 (40%), Positives = 50/90 (55%), Gaps = 6/90 (6%)
Query: 247 IITVTLNMEKYNFLGISIVGQSNERGDG-GIYIGSIMKGGAVAADGRIEPGDMLLQVNEI 305
IITVTL +K N +G+SIV D GIY+ S++KGGA DGR+ GD LL V+
Sbjct: 991 IITVTL--KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGR 1048
Query: 306 NFENMSNDDAVRVLREIVHKPGPITLTVAK 335
+ +S + A ++ +TL VAK
Sbjct: 1049 SLVGLSQERAAELM---TRTSSVVTLEVAK 1075
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 54.3 bits (129), Expect = 4e-07
Identities = 59/244 (24%), Positives = 93/244 (38%), Gaps = 23/244 (9%)
Query: 94 DNPSELPPPMERTGGIGDSRPPSFHPHAGGGSQENLDNDTETDSLVSAQRERPRRRDGPE 153
D S P E + D S +PH + + N V+ +P +
Sbjct: 955 DKASWEEKPREMSKSYHDLSQASLYPHR----KNVIVNMEPPPQTVAELVGKPSHQMSRS 1010
Query: 154 HATRLNGTAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSR-FSSSTEQSSASR 212
A L G K + + S E +++S D + SS SS
Sbjct: 1011 DAESLAGVTKLNNSKSVASLNRSPERRKHESDSSSIEDPGQAYVLGMTMHSSGNSSSQVP 1070
Query: 213 LMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVG-QSNER 271
L +R VS ER I V L + LG I+G + R
Sbjct: 1071 LKENDVLHKRWSIVSSPERE--------------ITLVNLKKDAKYGLGFQIIGGEKMGR 1116
Query: 272 GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITL 331
D GI+I S+ GG DG ++PGD L+ VN ++ E +S+ A+ +L+ + P +TL
Sbjct: 1117 LDLGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQ---NAPEDVTL 1173
Query: 332 TVAK 335
+++
Sbjct: 1174 VISQ 1177
Score = 54.3 bits (129), Expect = 4e-07
Identities = 57/235 (24%), Positives = 98/235 (41%), Gaps = 41/235 (17%)
Query: 116 SFHPHAG--GGSQENLDNDTETDSLVSAQRERPRRRDGPEHATRLNG---TAKGERRREP 170
SF P G GS + D+ TE+ SL +Q +NG + G++ +
Sbjct: 1232 SFGPSGGLREGSLSSQDSRTESASLSQSQ---------------VNGFFASHLGDQTWQE 1276
Query: 171 GGYDSSS-TLMSSELETTSFFDSDED-----------DSTSRFSSSTEQSSASRLMRRHK 218
+ S S +++S E +F DS++ D + R S ++++ S
Sbjct: 1277 SQHGSPSPSVISKATEKETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQT 1336
Query: 219 RRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIV------GQSNERG 272
++ +F + + S I + N LGIS+ G +
Sbjct: 1337 PKQESSSSVNTSNKMNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTVLFDKGGVNTSVR 1396
Query: 273 DGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR---EIVH 324
GGIY+ +++ GA +DGRI GD +L VN ++ E ++ AV LR ++VH
Sbjct: 1397 HGGIYVKAVIPQGAAESDGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVH 1451
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/119 (26%), Positives = 63/119 (52%), Gaps = 5/119 (4%)
Query: 202 SSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLG 261
S S SS + H +Q+ ++ + + D + + ++ + EK + LG
Sbjct: 1747 SESASSSSMDKYHIHHISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGS-LG 1805
Query: 262 ISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
++ + N+R G Y+ +++ A +DGR++PGD L++VN+ + NM++ DAV +LR
Sbjct: 1806 FTVT-KGNQRI--GCYVHDVIQDPA-KSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLR 1860
Score = 35.0 bits (79), Expect = 0.24
Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 19/129 (14%)
Query: 566 SSQHS--EGSRSSGSNRSGSDRRKE-KDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPS 622
SSQ S E S SS N +K+ K P DS S SGS D AP+
Sbjct: 1623 SSQPSCVEQSTSSDENEMSDKSKKQCKSPSRRDSYSDSSGSGEDDLVT---------APA 1673
Query: 623 ERSGPAASEHSHRSHHSLASSLRSHHTHPSYGPPGVPPLYGPPMLMMPPP------PAAM 676
S S H++ ++ S +SHH P + ++ P + P P+ +
Sbjct: 1674 NISNSTWSSALHQTLSNMVSQAQSHHEAPKSQEDTICTMFYYPQKIPNKPEFEDSNPSPL 1733
Query: 677 GPPGAPPGR 685
PP PG+
Sbjct: 1734 -PPDMAPGQ 1741
Score = 32.3 bits (72), Expect = 1.6
Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 9/101 (8%)
Query: 224 QKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSN---ERGDGGIY-IG 279
+KV + + +S +T+ N V L + + LG S + N E+ + I +
Sbjct: 1485 EKVKKTTQVKDYSFVTEE----NTFEVKL-FKNSSGLGFSFSREDNLIPEQINASIVRVK 1539
Query: 280 SIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
+ G A G+I+ GD++L+VN + + +S + + LR
Sbjct: 1540 KLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALR 1580
>gi|4557529 post-synaptic density protein 95 isoform 1 [Homo
sapiens]
Length = 767
Score = 53.9 bits (128), Expect = 5e-07
Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV
Sbjct: 213 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 272
Query: 317 RVLR 320
L+
Sbjct: 273 AALK 276
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G ++ D I+I I+ GGA A DGR+ D +L VNE++ +++ AV
Sbjct: 118 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 177
Query: 317 RVLRE 321
L+E
Sbjct: 178 EALKE 182
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L
Sbjct: 366 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 422
Query: 320 R 320
+
Sbjct: 423 K 423
>gi|192447426 post-synaptic density protein 95 isoform 2 [Homo
sapiens]
Length = 721
Score = 53.9 bits (128), Expect = 5e-07
Identities = 27/64 (42%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV
Sbjct: 167 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 226
Query: 317 RVLR 320
L+
Sbjct: 227 AALK 230
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/65 (38%), Positives = 37/65 (56%), Gaps = 3/65 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G ++ D I+I I+ GGA A DGR+ D +L VNE++ +++ AV
Sbjct: 72 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 131
Query: 317 RVLRE 321
L+E
Sbjct: 132 EALKE 136
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L
Sbjct: 320 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 376
Query: 320 R 320
+
Sbjct: 377 K 377
>gi|119943106 synapse-associated protein 102 isoform a [Homo
sapiens]
Length = 817
Score = 53.9 bits (128), Expect = 5e-07
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 10/82 (12%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI +G + GD IYI I++GGA DGR++ GD LL VN N +++ +++AV
Sbjct: 236 LGFSIAGGIGNQHIPGDNSIYITKIIEGGAAQKDGRLQIGDRLLAVNNTNLQDVRHEEAV 295
Query: 317 RVLREI-------VHKPGPITL 331
L+ V KPG + L
Sbjct: 296 ASLKNTSDMVYLKVAKPGSLHL 317
Score = 50.1 bits (118), Expect = 7e-06
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 7/85 (8%)
Query: 260 LGISIVG---QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G + D GI+I I+ GGA A DGR+ D +L+VNE++ + + AV
Sbjct: 141 LGFSIAGGIDNPHVPDDPGIFITKIIPGGAAAMDGRLGVNDCVLRVNEVDVSEVVHSRAV 200
Query: 317 RVLREIVHKPGPITLTVAKCWDPSP 341
L+E GP+ V + P P
Sbjct: 201 EALKE----AGPVVRLVVRRRQPPP 221
Score = 41.6 bits (96), Expect = 0.003
Identities = 22/61 (36%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I++ I+ GG G + GD +L VN +N N +++ A L
Sbjct: 396 LGFNIVG--GEDGEG-IFVSFILAGGPADLSGELRRGDRILSVNGVNLRNATHEQAAAAL 452
Query: 320 R 320
+
Sbjct: 453 K 453
>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
Length = 690
Score = 53.9 bits (128), Expect = 5e-07
Identities = 26/78 (33%), Positives = 49/78 (62%), Gaps = 1/78 (1%)
Query: 250 VTLNMEKYNFLGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFE 308
+T+ E + LG+++ G + ++ G+ I++ S+ G +A DGRI+ GD+LL +N I+
Sbjct: 469 ITVKKEPHESLGMTVAGGRGSKSGELPIFVTSVPPHGCLARDGRIKRGDVLLNINGIDLT 528
Query: 309 NMSNDDAVRVLREIVHKP 326
N+S+ +AV +L+ P
Sbjct: 529 NLSHSEAVAMLKASAASP 546
Score = 48.9 bits (115), Expect = 2e-05
Identities = 35/93 (37%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
Query: 233 SSFSSITDSTMSL---NIITVTLNMEK-YNFLGISIVGQSNERGDGGIYIGSIMKGGAVA 288
S+ + T +SL I T+ ++ Y LGISIVG NE I I + + G +A
Sbjct: 214 SAGADTTQQPLSLPEGEITTIEIHRSNPYIQLGISIVG-GNETPLINIVIQEVYRDGVIA 272
Query: 289 ADGRIEPGDMLLQVNEINFENMSNDDAVRVLRE 321
DGR+ GD +LQVN N N+S++ A VL +
Sbjct: 273 RDGRLLAGDQILQVNNYNISNVSHNYARAVLSQ 305
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/81 (37%), Positives = 44/81 (54%), Gaps = 5/81 (6%)
Query: 261 GISIVGQSNERGDGG-IYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
G SIVG E +I +I+ G DGR++ GDM++ VN ++ MS+ V +L
Sbjct: 612 GFSIVGGYEENHTNQPFFIKTIVLGTPAYYDGRLKCGDMIVAVNGLSTVGMSHSALVPML 671
Query: 320 REIVHKPGPITLTVAKCWDPS 340
+E +K +TLTV CW S
Sbjct: 672 KEQRNK---VTLTVI-CWPGS 688
Score = 38.5 bits (88), Expect = 0.022
Identities = 22/82 (26%), Positives = 46/82 (56%), Gaps = 6/82 (7%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LGI +V +++E G ++I +++GG A DGR+ D +L +N + + + + A +++
Sbjct: 351 LGIKLVRRTDEPG---VFILDLLEGGLAAQDGRLSSNDRVLAINGHDLKYGTPELAAQII 407
Query: 320 REIVHKPGPITLTVAKCWDPSP 341
+ + + LT+A+ P P
Sbjct: 408 QASGER---VNLTIARPGKPQP 426
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 53.1 bits (126), Expect = 9e-07
Identities = 40/135 (29%), Positives = 66/135 (48%), Gaps = 5/135 (3%)
Query: 191 DSDEDDSTSRFSSSTEQSSASRLMRRHKRRRRKQKVSRIERSSSFSSITDSTMSLNIIT- 249
DS S + +S +++S+ LM + + RSS+ + + II
Sbjct: 1566 DSQAVPSAAGAASGEKKNSSQSLMVPQSGSPEPESIRNTSRSSTPAIFASDPATCPIIPG 1625
Query: 250 --VTLNMEKYNF-LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEIN 306
T+ + K LG+SIVG S+ G I I + + GA DGR+ GD +L+VN I+
Sbjct: 1626 CETTIEISKGRTGLGLSIVGGSDTLL-GAIIIHEVYEEGAACKDGRLWAGDQILEVNGID 1684
Query: 307 FENMSNDDAVRVLRE 321
++D+A+ VLR+
Sbjct: 1685 LRKATHDEAINVLRQ 1699
Score = 51.2 bits (121), Expect = 3e-06
Identities = 26/73 (35%), Positives = 42/73 (57%), Gaps = 3/73 (4%)
Query: 248 ITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINF 307
+T+ L + LG+SIVG+ N D G+++ I+KGG ADGR+ GD +L VN +
Sbjct: 1724 LTIELQKKPGKGLGLSIVGKRN---DTGVFVSDIVKGGIADADGRLMQGDQILMVNGEDV 1780
Query: 308 ENMSNDDAVRVLR 320
N + + +L+
Sbjct: 1781 RNATQEAVAALLK 1793
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/78 (37%), Positives = 43/78 (55%), Gaps = 5/78 (6%)
Query: 260 LGISIVGQSNERG--DGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVR 317
LGI+I G ++ GI++ SI K AV DGRI+ GD ++ V+ N + +N AV
Sbjct: 387 LGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQIIAVDGTNLQGFTNQQAVE 446
Query: 318 VLREIVHKPGPITLTVAK 335
VLR H + LT+ +
Sbjct: 447 VLR---HTGQTVLLTLMR 461
Score = 48.9 bits (115), Expect = 2e-05
Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 4/75 (5%)
Query: 260 LGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRV 318
LG SIVG + GD IY+ ++ GA + DGR++ GD ++ VN + E +++++AV +
Sbjct: 1968 LGFSIVGGYGSPHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAI 2027
Query: 319 LREIVHKPGPITLTV 333
L+ G +TL V
Sbjct: 2028 LK---RTKGTVTLMV 2039
Score = 47.4 bits (111), Expect = 5e-05
Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 276 IYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAK 335
I I S++ GG DGR+ PGD L+ VN++N EN S ++AV L+ G + + VAK
Sbjct: 728 IIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLENSSLEEAVEALKGA--PSGTVRIGVAK 785
Query: 336 CWDPSP 341
SP
Sbjct: 786 PLPLSP 791
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/71 (36%), Positives = 44/71 (61%), Gaps = 4/71 (5%)
Query: 251 TLNMEKYNF-LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFEN 309
T+N+ K N LG+++ S + G+ + SI+ GGA++ DGRI GD +L +NE + +
Sbjct: 1008 TINIAKGNSSLGMTV---SANKDGLGMIVRSIIHGGAISRDGRIAIGDCILSINEESTIS 1064
Query: 310 MSNDDAVRVLR 320
++N A +LR
Sbjct: 1065 VTNAQARAMLR 1075
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/97 (30%), Positives = 49/97 (50%), Gaps = 13/97 (13%)
Query: 243 MSLNIITVTLNMEKYNF---LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDML 299
M +N V ++ K++ LGIS+ E G +I S++ G V G++ GD L
Sbjct: 545 MGINYEIVVAHVSKFSENSGLGISL-----EATVGHHFIRSVLPEGPVGHSGKLFSGDEL 599
Query: 300 LQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAKC 336
L+VN I ++ D V +L+E+ PI +T+ C
Sbjct: 600 LEVNGITLLGENHQDVVNILKEL-----PIEVTMVCC 631
Score = 40.0 bits (92), Expect = 0.008
Identities = 28/103 (27%), Positives = 52/103 (50%), Gaps = 9/103 (8%)
Query: 260 LGISIVG-QSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVN-EINFENMSNDDAVR 317
LG S+VG +S RG+ GI++ I +G DGR++ D +L +N + + +++ A+
Sbjct: 148 LGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILAINGQALDQTITHQQAIS 207
Query: 318 VLR------EIVHKPGPITLTVAKCWDPSPRGCFTL-PRSEPI 353
+L+ ++V G + V+ SP T+ S P+
Sbjct: 208 ILQKAKDTVQLVIARGSLPQLVSPIVSRSPSAASTISAHSNPV 250
Score = 39.7 bits (91), Expect = 0.010
Identities = 24/79 (30%), Positives = 42/79 (53%), Gaps = 7/79 (8%)
Query: 250 VTLNMEKYNFLGISIVGQ-------SNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQV 302
V L E LGISIVG SN GI+I +++ +G ++PGD +++V
Sbjct: 1152 VELWREPSKSLGISIVGGRGMGSRLSNGEVMRGIFIKHVLEDSPAGKNGTLKPGDRIVEV 1211
Query: 303 NEINFENMSNDDAVRVLRE 321
+ ++ + S++ AV +R+
Sbjct: 1212 DGMDLRDASHEQAVEAIRK 1230
Score = 36.6 bits (83), Expect = 0.083
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 4/62 (6%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG I+G G+ + +I+ GG GR+ GD +L++ + + MS++ +VL
Sbjct: 267 LGFGIIGGKAT----GVIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVAQVL 322
Query: 320 RE 321
R+
Sbjct: 323 RQ 324
Score = 34.3 bits (77), Expect = 0.41
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 252 LNMEK-YNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENM 310
+ +EK ++ LG+S+ G + +R ++I I GA DGR++ D LL++N
Sbjct: 1351 IELEKGHSGLGLSLAG-NKDRSRMSVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGR 1409
Query: 311 SNDDAVRVLR 320
S+ +A +++
Sbjct: 1410 SHQNASSIIK 1419
Score = 33.9 bits (76), Expect = 0.54
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 3/93 (3%)
Query: 229 IERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQ-SNERGDGGIYIGSIMKGGAV 287
+E SS +++ L TV + + LGISI G + GD I+I + G
Sbjct: 1815 LESSSKKNALASEIQGLR--TVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVA 1872
Query: 288 AADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
A ++ GD ++ + + E M++ AV +L+
Sbjct: 1873 AQTQKLRVGDRIVTICGTSTEGMTHTQAVNLLK 1905
Score = 32.3 bits (72), Expect = 1.6
Identities = 18/45 (40%), Positives = 27/45 (60%), Gaps = 3/45 (6%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNE 304
LGI+I S E G+ I S+ + G A DGR++ GD +L V++
Sbjct: 1493 LGIAI---SEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDD 1534
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 52.8 bits (125), Expect = 1e-06
Identities = 29/77 (37%), Positives = 42/77 (54%), Gaps = 3/77 (3%)
Query: 244 SLNIITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVN 303
+L I V L + LG+SIVG+ N G++I I+KGGA DGR+ GD +L VN
Sbjct: 1528 NLEIFPVDLQKKAGRGLGLSIVGKRN---GSGVFISDIVKGGAADLDGRLIQGDQILSVN 1584
Query: 304 EINFENMSNDDAVRVLR 320
+ N S + +L+
Sbjct: 1585 GEDMRNASQETVATILK 1601
Score = 47.8 bits (112), Expect = 4e-05
Identities = 25/66 (37%), Positives = 39/66 (59%), Gaps = 1/66 (1%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG+SIVG + I I + + GA A DGR+ GD +L+VN ++ N S+++A+ L
Sbjct: 1447 LGLSIVG-GKDTPLNAIVIHEVYEEGAAARDGRLWAGDQILEVNGVDLRNSSHEEAITAL 1505
Query: 320 REIVHK 325
R+ K
Sbjct: 1506 RQTPQK 1511
Score = 46.6 bits (109), Expect = 8e-05
Identities = 36/106 (33%), Positives = 49/106 (46%), Gaps = 17/106 (16%)
Query: 260 LGISIVGQSNERGDG---GIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LGI IVG G GIY+ SI+ G A +G I+ D ++ V+ +N + +N D V
Sbjct: 376 LGIRIVGYVGTSHTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAVDGVNIQGFANHDVV 435
Query: 317 RVLR---EIVHKPGPITLTVAKCWD-------PSPRGCFTLPRSEP 352
VLR ++VH +TL K PS RG P P
Sbjct: 436 EVLRNAGQVVH----LTLVRRKTSSSTSPLEPPSDRGTVVEPLKPP 477
Score = 43.9 bits (102), Expect = 5e-04
Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 231 RSSSFSSITDSTMSLNI----ITVTLNMEKYNFLGISIVGQSNERGDGGIYIGSIMKGGA 286
+SS+ SS+ D+T+ + + + + LG IVG G+ + +I+ GG
Sbjct: 225 KSSTSSSLNDTTLPETVCWGHVEEVELINDGSGLGFGIVGGKTS----GVVVRTIVPGGL 280
Query: 287 VAADGRIEPGDMLLQVNEINFENMSNDDAVRVLR 320
DGR++ GD +L++ N + M+++ +VLR
Sbjct: 281 ADRDGRLQTGDHILKIGGTNVQGMTSEQVAQVLR 314
Score = 43.5 bits (101), Expect = 7e-04
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 3/63 (4%)
Query: 273 DGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLT 332
DG YI SI+ GG V G ++P D LL+VN + S +AV L+E+ P P TL
Sbjct: 578 DGHHYISSIVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEV---PPPFTLV 634
Query: 333 VAK 335
+
Sbjct: 635 CCR 637
Score = 38.1 bits (87), Expect = 0.029
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 4/77 (5%)
Query: 276 IYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPITLTVAK 335
I I S++ G G + PGD L+ VNE +N S +AV +L+ + PG + L + K
Sbjct: 714 IVIRSLVADGVAERSGGLLPGDRLVSVNEYCLDNTSLAEAVEILKAV--PPGLVHLGICK 771
Query: 336 --CWDPSPRGCFTLPRS 350
D C+ L S
Sbjct: 772 PLVEDNEEESCYILHSS 788
Score = 37.7 bits (86), Expect = 0.037
Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 1/63 (1%)
Query: 258 NFLGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVR 317
N LG+S+ G + +R I++ I G AADGR+ GD LL++N S+ +A
Sbjct: 1247 NGLGLSLAG-NKDRSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQNASA 1305
Query: 318 VLR 320
+++
Sbjct: 1306 IIK 1308
Score = 34.7 bits (78), Expect = 0.32
Identities = 19/68 (27%), Positives = 37/68 (54%), Gaps = 7/68 (10%)
Query: 260 LGISIVGQSN-----ERGDG--GIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSN 312
LGISIVG + G+ GI+I +++ ++ GD +L+V+ ++ +N S+
Sbjct: 1079 LGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKILEVSGVDLQNASH 1138
Query: 313 DDAVRVLR 320
+AV ++
Sbjct: 1139 SEAVEAIK 1146
>gi|157388993 synaptojanin 2 binding protein [Homo sapiens]
Length = 145
Score = 52.8 bits (125), Expect = 1e-06
Identities = 26/64 (40%), Positives = 41/64 (64%), Gaps = 3/64 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG +IVG ++++ D GIY+ I + GA A DGR++ GD +L VN + +N+ + DAV
Sbjct: 23 LGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLLHQDAV 82
Query: 317 RVLR 320
+ R
Sbjct: 83 DLFR 86
>gi|21361831 partitioning-defective protein 3 homolog [Homo sapiens]
Length = 1356
Score = 52.4 bits (124), Expect = 1e-06
Identities = 35/102 (34%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Query: 240 DSTMSLNIITVTLNMEKYNFLGISIVGQSNERG--DGGIYIGSIMKGGAVAADGRIEPGD 297
D T V LN LG+S+ G ++ D GI++ SI+ GGA + DGR+ D
Sbjct: 581 DGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVND 640
Query: 298 MLLQVNEINFENMSNDDAVRVLREIV----HKPGPITLTVAK 335
L+ VN + +N DA+ LR + +K G I L VA+
Sbjct: 641 QLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVAR 682
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 260 LGISIVGQS-NERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRV 318
LG SI + G IY+ +I+ GA DGR++ GD L++VN ++ S ++ V +
Sbjct: 471 LGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSL 530
Query: 319 LREIVHKPGPITLTV 333
LR G ++L V
Sbjct: 531 LRS-TKMEGTVSLLV 544
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 52.0 bits (123), Expect = 2e-06
Identities = 52/173 (30%), Positives = 60/173 (34%), Gaps = 15/173 (8%)
Query: 523 PLPHPGAA-PWPMAFPYQYPPPPHPYNPHPGFPELGYSYGGGSASSQHSEGSRSSGSNRS 581
PL P A P P PPPP P + P P G + +S G+ S+G
Sbjct: 290 PLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVGAASTGGGTG 349
Query: 582 GSDRRKEKDPKA------GDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHR 635
G+ A G S G + G R SE EH R
Sbjct: 350 GTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRER 409
Query: 636 SHHSLAS----SLRSHHTHPSY-GPPGVPPLYGPPMLMMPPPPAAMGPPGAPP 683
S +L LRS T P GPPG GPP PPP PP APP
Sbjct: 410 SLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPPPP---QQPPTAPP 459
Score = 30.4 bits (67), Expect = 6.0
Identities = 55/228 (24%), Positives = 72/228 (31%), Gaps = 69/228 (30%)
Query: 524 LPHPGAAPWPMAFPYQY-----PPPPHPYNPHPGFPELGYSYGGGSASSQHSE------- 571
LPHP P + P P P P +P G + G G A SQH
Sbjct: 10 LPHPRRREAPGSPPLSPRGHCPPAPAKPMHPENKLTNHGKT-GNGGAQSQHQNVNQGPTC 68
Query: 572 --GSRSSGSNRSGSDRRKE-------KDPKAG--------------DSKSGGSGSESDHT 608
GS+ G+ G+ + K+P+AG S S SG + +
Sbjct: 69 NVGSKGVGAGNHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRDRSVSVDSGEQREAG 128
Query: 609 TRSSLRGPRERAPS-------ERSGPAASEHSHRSHHSLASSLRSHHTH----------- 650
T S +E AP ER P + + S TH
Sbjct: 129 TPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNCNVADPAMAA 188
Query: 651 PSYGP-------------PGVPPLYGPPMLMMPPPPAAMGPPGAPPGR 685
P GP PG P +GPP + P P G G PG+
Sbjct: 189 PQLGPGQTTQLPLSESSVPGAP--HGPPPGLRPDAPGGGGGGGGVPGK 234
>gi|148539628 discs, large homolog 1 isoform 1 [Homo sapiens]
Length = 904
Score = 51.2 bits (121), Expect = 3e-06
Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI VG + GD IY+ I++GGA DG+++ GD LL VN + E +++++AV
Sbjct: 329 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAV 388
Query: 317 RVLR 320
L+
Sbjct: 389 TALK 392
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/65 (38%), Positives = 39/65 (60%), Gaps = 3/65 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G ++ D I+I I+ GGA A DGR+ D +L+VNE++ ++++ AV
Sbjct: 234 LGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAV 293
Query: 317 RVLRE 321
L+E
Sbjct: 294 EALKE 298
Score = 38.5 bits (88), Expect = 0.022
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I+I I+ GG G + GD ++ VN ++ S++ A L
Sbjct: 476 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAAL 532
Query: 320 R 320
+
Sbjct: 533 K 533
>gi|148539578 discs, large homolog 1 isoform 2 [Homo sapiens]
Length = 926
Score = 51.2 bits (121), Expect = 3e-06
Identities = 26/64 (40%), Positives = 40/64 (62%), Gaps = 3/64 (4%)
Query: 260 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI VG + GD IY+ I++GGA DG+++ GD LL VN + E +++++AV
Sbjct: 329 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGKLQIGDKLLAVNNVCLEEVTHEEAV 388
Query: 317 RVLR 320
L+
Sbjct: 389 TALK 392
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/65 (38%), Positives = 39/65 (60%), Gaps = 3/65 (4%)
Query: 260 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAV 316
LG SI G ++ D I+I I+ GGA A DGR+ D +L+VNE++ ++++ AV
Sbjct: 234 LGFSIAGGTDNPHIGDDSSIFITKIITGGAAAQDGRLRVNDCILRVNEVDVRDVTHSKAV 293
Query: 317 RVLRE 321
L+E
Sbjct: 294 EALKE 298
Score = 38.5 bits (88), Expect = 0.022
Identities = 21/61 (34%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 260 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVL 319
LG +IVG E G+G I+I I+ GG G + GD ++ VN ++ S++ A L
Sbjct: 476 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDRIISVNSVDLRAASHEQAAAAL 532
Query: 320 R 320
+
Sbjct: 533 K 533
>gi|119120907 par-3 partitioning defective 3 homolog B isoform a
[Homo sapiens]
Length = 1104
Score = 51.2 bits (121), Expect = 3e-06
Identities = 62/236 (26%), Positives = 98/236 (41%), Gaps = 15/236 (6%)
Query: 101 PPMERTGGIGDSRPPSFHPHAGGGSQEN-----LDNDTETDSLVSAQRERPRRRDGPEHA 155
P + R GG S PS P G GS +N +D + L R GP
Sbjct: 353 PRVPRLGGKPSS--PSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPI 410
Query: 156 TRLNGTAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMR 215
N KG ++ G S ++ E+ +++ + S+ + +AS ++
Sbjct: 411 FVKNILPKGAAIKD-GRLQSGDRIL--EVNGRDVTGRTQEELVAMLRSTKQGETASLVIA 467
Query: 216 RHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVG-QSNERG-D 273
R + +++ + S T ++ I LN LG+S+ G +S E G D
Sbjct: 468 RQEGHFLPRELKGEPDCCALSLETSEQLTFEI---PLNDSGSAGLGVSLKGNKSRETGTD 524
Query: 274 GGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPI 329
GI+I SI+ GGA DGR+ D L+ VN + SN +A+ LR + G I
Sbjct: 525 LGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNI 580
>gi|119120903 par-3 partitioning defective 3 homolog B isoform c
[Homo sapiens]
Length = 1136
Score = 51.2 bits (121), Expect = 3e-06
Identities = 62/236 (26%), Positives = 98/236 (41%), Gaps = 15/236 (6%)
Query: 101 PPMERTGGIGDSRPPSFHPHAGGGSQEN-----LDNDTETDSLVSAQRERPRRRDGPEHA 155
P + R GG S PS P G GS +N +D + L R GP
Sbjct: 353 PRVPRLGGKPSS--PSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPI 410
Query: 156 TRLNGTAKGERRREPGGYDSSSTLMSSELETTSFFDSDEDDSTSRFSSSTEQSSASRLMR 215
N KG ++ G S ++ E+ +++ + S+ + +AS ++
Sbjct: 411 FVKNILPKGAAIKD-GRLQSGDRIL--EVNGRDVTGRTQEELVAMLRSTKQGETASLVIA 467
Query: 216 RHKRRRRKQKVSRIERSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVG-QSNERG-D 273
R + +++ + S T ++ I LN LG+S+ G +S E G D
Sbjct: 468 RQEGHFLPRELKGEPDCCALSLETSEQLTFEI---PLNDSGSAGLGVSLKGNKSRETGTD 524
Query: 274 GGIYIGSIMKGGAVAADGRIEPGDMLLQVNEINFENMSNDDAVRVLREIVHKPGPI 329
GI+I SI+ GGA DGR+ D L+ VN + SN +A+ LR + G I
Sbjct: 525 LGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNI 580
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,319,286
Number of Sequences: 37866
Number of extensions: 2061998
Number of successful extensions: 21202
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 320
Number of HSP's successfully gapped in prelim test: 909
Number of HSP's that attempted gapping in prelim test: 11926
Number of HSP's gapped (non-prelim): 7837
length of query: 716
length of database: 18,247,518
effective HSP length: 109
effective length of query: 607
effective length of database: 14,120,124
effective search space: 8570915268
effective search space used: 8570915268
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.