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Search of human proteins with 41406080
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
(476 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 976 0.0
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 846 0.0
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 839 0.0
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 643 0.0
gi|20149528 proline-serine-threonine phosphatase interacting pro... 92 1e-18
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 88 2e-17
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 88 2e-17
gi|239049440 FCH domain only 1 isoform a [Homo sapiens] 88 2e-17
gi|165905601 proline-serine-threonine phosphatase interacting pr... 83 6e-16
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 79 7e-15
gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 77 3e-14
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap... 72 1e-12
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens] 58 2e-08
gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-lik... 57 5e-08
gi|38524622 formin binding protein 1 [Homo sapiens] 57 5e-08
gi|197313748 SET domain containing 2 [Homo sapiens] 56 8e-08
gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens] 55 1e-07
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 54 3e-07
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 54 4e-07
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 54 4e-07
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 51 2e-06
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 51 2e-06
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 51 2e-06
gi|148747351 protein kinase C and casein kinase substrate in neu... 51 3e-06
gi|224177511 sorting nexin 18 isoform c [Homo sapiens] 49 1e-05
gi|157057545 sorting nexin 18 isoform a [Homo sapiens] 49 1e-05
gi|157057543 sorting nexin 18 isoform b [Homo sapiens] 49 1e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 1e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 49 1e-05
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 49 1e-05
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 976 bits (2522), Expect = 0.0
Identities = 476/476 (100%), Positives = 476/476 (100%)
Query: 1 MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL 60
MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL
Sbjct: 1 MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL 60
Query: 61 EKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGS 120
EKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGS
Sbjct: 61 EKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGS 120
Query: 121 HRSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVT 180
HRSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVT
Sbjct: 121 HRSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVT 180
Query: 181 FPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEF 240
FPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEF
Sbjct: 181 FPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEF 240
Query: 241 IRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEV 300
IRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEV
Sbjct: 241 IRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEV 300
Query: 301 EKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIK 360
EKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIK
Sbjct: 301 EKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIK 360
Query: 361 LSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIR 420
LSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIR
Sbjct: 361 LSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIR 420
Query: 421 QHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 476
QHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI
Sbjct: 421 QHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 476
>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
Length = 416
Score = 846 bits (2185), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 62 KPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSH 121
KPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSH
Sbjct: 2 KPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSH 61
Query: 122 RSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTF 181
RSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTF
Sbjct: 62 RSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTF 121
Query: 182 PHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFI 241
PHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFI
Sbjct: 122 PHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFI 181
Query: 242 RERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVE 301
RERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVE
Sbjct: 182 RERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVE 241
Query: 302 KPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKL 361
KPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKL
Sbjct: 242 KPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKL 301
Query: 362 SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQ 421
SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQ
Sbjct: 302 SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQ 361
Query: 422 HLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 476
HLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI
Sbjct: 362 HLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 416
>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
Length = 412
Score = 839 bits (2167), Expect = 0.0
Identities = 412/412 (100%), Positives = 412/412 (100%)
Query: 65 MVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSHRSS 124
MVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSHRSS
Sbjct: 1 MVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSHRSS 60
Query: 125 LPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTFPHP 184
LPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTFPHP
Sbjct: 61 LPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKENTITINCVTFPHP 120
Query: 185 DTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRER 244
DTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRER
Sbjct: 121 DTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRER 180
Query: 245 IKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPL 304
IKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPL
Sbjct: 181 IKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPL 240
Query: 305 MNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNK 364
MNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNK
Sbjct: 241 MNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNK 300
Query: 365 TEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLC 424
TEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLC
Sbjct: 301 TEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLC 360
Query: 425 QYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 476
QYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI
Sbjct: 361 QYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 412
>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
Length = 336
Score = 643 bits (1659), Expect = 0.0
Identities = 320/320 (100%), Positives = 320/320 (100%)
Query: 157 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 216
QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT
Sbjct: 17 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 76
Query: 217 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 276
VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA
Sbjct: 77 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 136
Query: 277 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 336
QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV
Sbjct: 137 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 196
Query: 337 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 396
EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK
Sbjct: 197 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 256
Query: 397 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 456
WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD
Sbjct: 257 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 316
Query: 457 RELWVREHKTGNIRPVDMEI 476
RELWVREHKTGNIRPVDMEI
Sbjct: 317 RELWVREHKTGNIRPVDMEI 336
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 91.7 bits (226), Expect = 1e-18
Identities = 62/260 (23%), Positives = 125/260 (48%), Gaps = 8/260 (3%)
Query: 219 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQV 278
G+E+LLQ+ L G++M K+M E +R+R + EE Y K L ++++ + E SL ++ +
Sbjct: 21 GYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSL 80
Query: 279 KKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEK 338
K+ + + H++ + L E+ + L FRE K+ KK + + ++K S Y +
Sbjct: 81 KQQMENVGSSHIQLALTLREEL-RSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAME 139
Query: 339 ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQA----- 393
++K ++ RD + Q E +N ++ ++K++ K+ Q D +Y Q+
Sbjct: 140 SKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLE 199
Query: 394 --QSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKV 451
+++W +E TT + E +R+ ++R L ++ + + E V L
Sbjct: 200 KVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGC 259
Query: 452 DPAKDRELWVREHKTGNIRP 471
D + +++ TG P
Sbjct: 260 SIDADIDSFIQAKSTGTEPP 279
Score = 36.2 bits (82), Expect = 0.067
Identities = 17/54 (31%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
Query: 7 RTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL 60
R LY ++ + + L +AG+++ ++ + GWW E+ +G RG+ P SY++ L
Sbjct: 365 RALYDYTAQNPDE-LDLSAGDILEVILEGEDGWWTVER-NGQRGFVPGSYLEKL 416
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 87.8 bits (216), Expect = 2e-17
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 202 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 261
++FW +K GFE+L +G KE+++FIRER IEE Y+K +AKLS+
Sbjct: 6 EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
Query: 262 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 321
+ G+ W + S A HL+ + KL ++ K ++ + E K KKC
Sbjct: 58 ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
Query: 322 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 378
+ D + L+ + K+R+ R D E ++ + +++++ KA K+ +
Sbjct: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
Query: 379 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 433
A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y +T
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 434 ---DMFNQSTVE-PVDQLLRKVDPAK 455
+ F Q+ V+ LLRK +K
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 87.8 bits (216), Expect = 2e-17
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 202 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 261
++FW +K GFE+L +G KE+++FIRER IEE Y+K +AKLS+
Sbjct: 6 EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
Query: 262 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 321
+ G+ W + S A HL+ + KL ++ K ++ + E K KKC
Sbjct: 58 ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
Query: 322 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 378
+ D + L+ + K+R+ R D E ++ + +++++ KA K+ +
Sbjct: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
Query: 379 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 433
A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y +T
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 434 ---DMFNQSTVE-PVDQLLRKVDPAK 455
+ F Q+ V+ LLRK +K
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
Length = 891
Score = 87.8 bits (216), Expect = 2e-17
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 202 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 261
++FW +K GFE+L +G KE+++FIRER IEE Y+K +AKLS+
Sbjct: 6 EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
Query: 262 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 321
+ G+ W + S A HL+ + KL ++ K ++ + E K KKC
Sbjct: 58 ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
Query: 322 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 378
+ D + L+ + K+R+ R D E ++ + +++++ KA K+ +
Sbjct: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
Query: 379 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 433
A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y +T
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 434 ---DMFNQSTVE-PVDQLLRKVDPAK 455
+ F Q+ V+ LLRK +K
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
>gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
Length = 334
Score = 82.8 bits (203), Expect = 6e-16
Identities = 65/261 (24%), Positives = 116/261 (44%), Gaps = 9/261 (3%)
Query: 219 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE-GSLGEAWAQ 277
G++ ++Q G++ KE +F++ER IEE Y K+L LS+ Q E +L A
Sbjct: 20 GYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEV 79
Query: 278 VKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVE 337
K+ + + A+ H++ + L E K + FRE K KK + + + KQ + ++
Sbjct: 80 FKQQVDNVAQCHIQLAQSLREEARK-MEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTM 138
Query: 338 KARKALTERQRDLEMKTQQL--EIKLSNKTEED---IKKARRKSTQAGDD--LMRCVDLY 390
A+K ++ RD + Q + L N +++ +K A K+ D M +
Sbjct: 139 DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTL 198
Query: 391 NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRK 450
++ + +W E + E E ER+ R L + + + + E V + L
Sbjct: 199 DKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEM 258
Query: 451 VDPAKDRELWVREHKTGNIRP 471
+D E +V + KTG I P
Sbjct: 259 CSIQRDIEYFVNQRKTGQIPP 279
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 79.3 bits (194), Expect = 7e-15
Identities = 55/223 (24%), Positives = 107/223 (47%), Gaps = 14/223 (6%)
Query: 200 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 259
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
Query: 260 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 319
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
Query: 320 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 378
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
Query: 379 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQ 421
A D V+ Y A++ + ++M T + + +E + I++
Sbjct: 173 ATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKE 215
>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
Length = 777
Score = 77.4 bits (189), Expect = 3e-14
Identities = 55/210 (26%), Positives = 102/210 (48%), Gaps = 15/210 (7%)
Query: 200 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 259
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
Query: 260 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 319
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
Query: 320 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 378
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
Query: 379 AGDDLMRCVDLYNQAQSKWFEEMVTTTLEL 408
A D V+ Y A++ FE+ +T T ++
Sbjct: 173 ATDTYKLYVEKYALAKAD-FEQKMTETAQV 201
>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
sapiens]
Length = 506
Score = 72.0 bits (175), Expect = 1e-12
Identities = 57/247 (23%), Positives = 108/247 (43%), Gaps = 16/247 (6%)
Query: 230 GKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN---SLASQEEGSLGEAWAQVKKSLADEA 286
G+ K+++ +++R +E YAK L KL+ +L + + + AWA + + A
Sbjct: 24 GENFCKQVTSVLQQRANLEISYAKGLQKLASKLSKALQNTRKSCVSSAWAWASEGMKSTA 83
Query: 287 EVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTER 346
++H K + E KP +K K D+ + + S + KA+K L
Sbjct: 84 DLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVS 143
Query: 347 QRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQ-------AQSKWFE 399
+ E Q +E + TE++ +K K T++ + L + + Y Q + KW
Sbjct: 144 TKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWEN 203
Query: 400 EMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQL---LRKVDPAKD 456
+ + LE ER++++ +L QY+Q +F Q+ Q+ + K+D KD
Sbjct: 204 TLENCYQSILELEKERIQLLCNNLNQYSQ---HISLFGQTLTTCHTQIHCAISKIDIEKD 260
Query: 457 RELWVRE 463
+ + E
Sbjct: 261 IQAVMEE 267
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 1 MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL 60
+S C+ LY F R L G+++ + + + GWW G +G +G FPA+YV+ L
Sbjct: 438 LSSRLCKALYSFQA-RQDDELNLEKGDIVIIHEKKEEGWWFGSL-NGKKGHFPAAYVEEL 495
>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
Length = 511
Score = 58.2 bits (139), Expect = 2e-08
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 25/159 (15%)
Query: 1 MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPD--GGWWEGEKE-DGLRGWFPASYV 57
M + +T++P + + L FA G++ITLL +P+ GW GE + RGWFP+SY
Sbjct: 339 MKKQKVKTIFPHTAGSNKTLLSFAQGDVITLL-IPEEKDGWLYGEHDVSKARGWFPSSYT 397
Query: 58 QLLEK--------PGMVPPPP--------GEESQTVILPPGWQSYLS---PQGRRYYVNT 98
+LLE+ P P P E S VI PP + LS RR ++
Sbjct: 398 KLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRR--ADS 455
Query: 99 TTNETTWERPSSSPGIPASPGSHRSSLPPTVNGYHASGT 137
+T++ P+S P A ++ ++ PP ++G + T
Sbjct: 456 ARTTSTFKAPASKPETAAPNDANGTAKPPFLSGENPFAT 494
>gi|4885153 v-crk sarcoma virus CT10 oncogene homolog (avian)-like
[Homo sapiens]
Length = 303
Score = 56.6 bits (135), Expect = 5e-08
Identities = 37/125 (29%), Positives = 53/125 (42%), Gaps = 17/125 (13%)
Query: 7 RTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLLEKPGMV 66
RTLY F G + L F GE++ +++ P+ WW +DG G P YV+ L +
Sbjct: 129 RTLYDFPGN-DAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEKLVRSSPH 187
Query: 67 PPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPSSSPGIPASPGSHRSSLP 126
S + +P +Y PQ TTT P + SPG+ + LP
Sbjct: 188 GKHGNRNSNSYGIPEPAHAYAQPQ-------TTT---------PLPAVSGSPGAAITPLP 231
Query: 127 PTVNG 131
T NG
Sbjct: 232 STQNG 236
>gi|38524622 formin binding protein 1 [Homo sapiens]
Length = 617
Score = 56.6 bits (135), Expect = 5e-08
Identities = 56/268 (20%), Positives = 112/268 (41%), Gaps = 27/268 (10%)
Query: 230 GKQMQKEMSEFIRERIKIEEDYAK---NLAKLSQNSLASQEEGSLG----EAWAQVKKSL 282
G + ++ +F++ER +IE YAK NL+K Q S+EE +A+ +
Sbjct: 21 GIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYKYTSCKAFISNLNEM 80
Query: 283 ADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMK-------KCDHHIADLRKQLASRYAS 335
D A H S + S++ L + + K++ K K HI KQL S
Sbjct: 81 NDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRR 140
Query: 336 VEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRK-------STQAGDDLMRCVD 388
E+ K Q+ E + N T+ D++KAR++ + + D +
Sbjct: 141 FERDCKEADRAQQYFEKMDADI-----NVTKADVEKARQQAQIRHQMAEDSKADYSSILQ 195
Query: 389 LYNQAQSKWFEEMVTTTLE-LERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQL 447
+N Q +++ + + ++ +E R+ + + + Y ++ + ++ + +
Sbjct: 196 KFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKA 255
Query: 448 LRKVDPAKDRELWVREHKTGNIRPVDME 475
+D D +L + +K+G P D+E
Sbjct: 256 AESIDQKNDSQLVIEAYKSGFEPPGDIE 283
Score = 33.5 bits (75), Expect = 0.43
Identities = 16/55 (29%), Positives = 28/55 (50%), Gaps = 2/55 (3%)
Query: 6 CRTLYPFSGERHGQGLRFAAGELITLLQVPDG-GWWEGEKEDGLRGWFPASYVQL 59
C+ LY F G+ G + GE + +++ G GW + + G+ P SYV++
Sbjct: 555 CKALYTFEGQNEGT-ISVVEGETLYVIEEDKGDGWTRIRRNEDEEGYVPTSYVEV 608
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 55.8 bits (133), Expect = 8e-08
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 13/107 (12%)
Query: 66 VPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTTTNETTWERPS-SSPGIPASPGSHRSS 124
+PPP + +T++LPP W++ P+G+ YY + T +T W+ P+ SPG AS H +
Sbjct: 2378 LPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASL-EHEAE 2436
Query: 125 LPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSPSKKQSKE 171
+ GTP + S + T ++ +SS K+SKE
Sbjct: 2437 MD--------LGTPTYDENPMKASKKPKTAEAD---TSSELAKKSKE 2472
>gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens]
Length = 545
Score = 55.1 bits (131), Expect = 1e-07
Identities = 55/274 (20%), Positives = 118/274 (43%), Gaps = 19/274 (6%)
Query: 220 FELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLAS-------QEEGSLG 272
FE+L + G + +F++ER ++E+ YAK L L + L + + S
Sbjct: 11 FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70
Query: 273 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASR 332
+++ Q+ + + D A + L V L + + K++ K ++QL +
Sbjct: 71 QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130
Query: 333 YASVEKARKALTERQRDLEMKTQQLEIKLS---NKTEEDIKKARRK-------STQAGDD 382
+ +E +++ R+ E Q E +L N T+ D++KA+++ + ++ ++
Sbjct: 131 FKQLENSKRKFERDCREAEKAAQTAE-RLDQDINATKADVEKAKQQAHLRSHMAEESKNE 189
Query: 383 LMRCVDLYNQAQSK-WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTV 441
+ +N+ Q+ +F +M +L+ ++ R + ++ E +
Sbjct: 190 YAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCL 249
Query: 442 EPVDQLLRKVDPAKDRELWVREHKTGNIRPVDME 475
E + VDP D + + HK+G RP D+E
Sbjct: 250 EGMKVAANAVDPKNDSHVLIELHKSGFARPGDVE 283
Score = 33.9 bits (76), Expect = 0.33
Identities = 17/55 (30%), Positives = 30/55 (54%), Gaps = 2/55 (3%)
Query: 6 CRTLYPFSGERHGQGLRFAAGELITLLQVPDG-GWWEGEKEDGLRGWFPASYVQL 59
C +Y F G G + A GE ++L++ G GW +++G G+ P SY+++
Sbjct: 489 CVAIYHFEGSSEGT-ISMAEGEDLSLMEEDKGDGWTRVRRKEGGEGYVPTSYLRV 542
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/213 (23%), Positives = 96/213 (45%), Gaps = 19/213 (8%)
Query: 255 LAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKD 314
+AKLS+ + G+ W + S A HL+ + KL ++ K ++ + E K
Sbjct: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKT 59
Query: 315 MKKCDHHIA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKK 371
KKC + D + L+ + K+R+ R D E ++ + +++++ K
Sbjct: 60 HKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDK 113
Query: 372 ARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRH 431
A K+ +A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y
Sbjct: 114 AETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVE 173
Query: 432 ET--------DMFNQSTVE-PVDQLLRKVDPAK 455
+T + F Q+ V+ LLRK +K
Sbjct: 174 DTHVQIGQVHEEFKQNIENVSVEMLLRKFAESK 206
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 53.5 bits (127), Expect = 4e-07
Identities = 49/178 (27%), Positives = 73/178 (41%), Gaps = 22/178 (12%)
Query: 6 CRTLYPFSGERHGQGLRFAAGELITLLQVP--DGGWWEGEKEDGLRGWFPASYVQLL--- 60
C+ ++P+ + + L G+++TL+ D GWWEGE +G RG FP ++V+LL
Sbjct: 235 CKVIFPYEAQNDDE-LTIKEGDIVTLINKDCIDVGWWEGEL-NGRRGVFPDNFVKLLPPD 292
Query: 61 -EKPGMVPPPPGEESQTVILPPGWQS-------YLSPQGRRYYVNTTTNETTWERPS--- 109
EK G P P S VI + + P+ N T + ER
Sbjct: 293 FEKEGNRPKKPPPPSAPVIKQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLD 352
Query: 110 -SSPGIPASPGSHRSSLPPTVNGYHASGT-PAHPPETAHMSVRKSTGDSQNLGSSSPS 165
P +PA P + PP N G P PE + + GDS + + S
Sbjct: 353 LQKPSVPAIP--PKKPRPPKTNSLSRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSS 408
Score = 32.3 bits (72), Expect = 0.97
Identities = 15/56 (26%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL 60
RC+ + + + + L G++I ++ + GWWEG +G G FP+++++ L
Sbjct: 65 RCQVAFSYLPQNDDE-LELKVGDIIEVVGEVEEGWWEGVL-NGKTGMFPSNFIKEL 118
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 53.5 bits (127), Expect = 4e-07
Identities = 49/178 (27%), Positives = 73/178 (41%), Gaps = 22/178 (12%)
Query: 6 CRTLYPFSGERHGQGLRFAAGELITLLQVP--DGGWWEGEKEDGLRGWFPASYVQLL--- 60
C+ ++P+ + + L G+++TL+ D GWWEGE +G RG FP ++V+LL
Sbjct: 272 CKVIFPYEAQNDDE-LTIKEGDIVTLINKDCIDVGWWEGEL-NGRRGVFPDNFVKLLPPD 329
Query: 61 -EKPGMVPPPPGEESQTVILPPGWQS-------YLSPQGRRYYVNTTTNETTWERPS--- 109
EK G P P S VI + + P+ N T + ER
Sbjct: 330 FEKEGNRPKKPPPPSAPVIKQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPEREPKLD 389
Query: 110 -SSPGIPASPGSHRSSLPPTVNGYHASGT-PAHPPETAHMSVRKSTGDSQNLGSSSPS 165
P +PA P + PP N G P PE + + GDS + + S
Sbjct: 390 LQKPSVPAIP--PKKPRPPKTNSLSRPGALPPRRPERPVGPLTHTRGDSPKIDLAGSS 445
Score = 45.4 bits (106), Expect = 1e-04
Identities = 20/47 (42%), Positives = 32/47 (68%), Gaps = 1/47 (2%)
Query: 16 RHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLLEK 62
+H L + GE+IT ++ DGGWWEG+ +G RG FP ++V+ ++K
Sbjct: 13 QHDDELTISVGEIITNIRKEDGGWWEGQ-INGRRGLFPDNFVREIKK 58
Score = 32.3 bits (72), Expect = 0.97
Identities = 15/56 (26%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPDGGWWEGEKEDGLRGWFPASYVQLL 60
RC+ + + + + L G++I ++ + GWWEG +G G FP+++++ L
Sbjct: 102 RCQVAFSYLPQNDDE-LELKVGDIIEVVGEVEEGWWEGVL-NGKTGMFPSNFIKEL 155
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/229 (20%), Positives = 113/229 (49%), Gaps = 37/229 (16%)
Query: 228 LKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEG-SLGEAWAQVKKSLADEA 286
+K ++M ++ +RE + +ED + + L + LA+Q E S+ + +++ +A++
Sbjct: 295 IKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKD 354
Query: 287 EVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTER 346
+H + K + ++++ L + ++ ++K + + ++ +LA R A++ KA ER
Sbjct: 355 SMHRQTEDK-NRQLQERLELAEQKLQQTLRKAE-TLPEVEAELAQRVAALSKAE----ER 408
Query: 347 QRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTL 406
++E + +Q+E +L K +E +++AR++ + N+ +K + V
Sbjct: 409 HGNIEERLRQMEAQLEEKNQE-LQRARQR------------EKMNEEHNKRLSDTV---- 451
Query: 407 ELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAK 455
++L E E ++ HL + + +E + LLR+V+ AK
Sbjct: 452 --DKLLSESNERLQLHLKE-----------RMAALEDKNSLLREVESAK 487
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 51.2 bits (121), Expect = 2e-06
Identities = 48/229 (20%), Positives = 113/229 (49%), Gaps = 37/229 (16%)
Query: 228 LKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEG-SLGEAWAQVKKSLADEA 286
+K ++M ++ +RE + +ED + + L + LA+Q E S+ + +++ +A++
Sbjct: 295 IKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKD 354
Query: 287 EVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTER 346
+H + K + ++++ L + ++ ++K + + ++ +LA R A++ KA ER
Sbjct: 355 SMHRQTEDK-NRQLQERLELAEQKLQQTLRKAE-TLPEVEAELAQRVAALSKAE----ER 408
Query: 347 QRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTL 406
++E + +Q+E +L K +E +++AR++ + N+ +K + V
Sbjct: 409 HGNIEERLRQMEAQLEEKNQE-LQRARQR------------EKMNEEHNKRLSDTV---- 451
Query: 407 ELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAK 455
++L E E ++ HL + + +E + LLR+V+ AK
Sbjct: 452 --DKLLSESNERLQLHLKE-----------RMAALEDKNSLLREVESAK 487
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 51.2 bits (121), Expect = 2e-06
Identities = 45/230 (19%), Positives = 110/230 (47%), Gaps = 9/230 (3%)
Query: 229 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEG-SLGEAWAQVKKSLADEAE 287
K ++ ++ ++E + ED + + L + L++Q E SL +A +++ LA +
Sbjct: 279 KAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKES 338
Query: 288 VHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQ 347
++ + K E L + ++ ++ ++K + + ++ QLA R A++ KA ER
Sbjct: 339 LYRQSEEKSRQLAEW-LDDAKQKLQQTLQKAET-LPEIEAQLAQRVAALNKAE----ERH 392
Query: 348 RDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLE 407
+ E + +QLE +L K +E +++AR++ D R + ++ S+ E + L+
Sbjct: 393 GNFEERLRQLEAQLEEKNQE-LQRARQREKMNDDHNKRLSETVDKLLSE-SNERLQLHLK 450
Query: 408 LERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDR 457
+E + + + +L+ E + + + ++++ ++D + R
Sbjct: 451 ERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGR 500
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 50.8 bits (120), Expect = 3e-06
Identities = 53/276 (19%), Positives = 119/276 (43%), Gaps = 28/276 (10%)
Query: 217 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE----GSLG 272
V ++ +++ G ++ ++ + ER +IE+ YA+ L + ++ E+ G++
Sbjct: 21 VGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVE 80
Query: 273 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNF-RENFKKDM-------KKCDHHIAD 324
+AW +E+HL+ A L ++ + + N+ +E F K M K+ +
Sbjct: 81 KAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRK 140
Query: 325 LRKQLASRYASVEKARKA--LTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDD 382
+K A + VE A+KA ++ L + + + E +KK + K + D
Sbjct: 141 AQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQD 200
Query: 383 LMRCVDLY-------NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDM 435
+++ + Y +Q ++ E M + ++ E +R+ R+ L +++ D+
Sbjct: 201 VLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVL---LEVQKHLDL 257
Query: 436 FN----QSTVEPVDQLLRKVDPAKDRELWVREHKTG 467
N ++ ++Q +R D +D + H G
Sbjct: 258 SNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPG 293
Score = 43.1 bits (100), Expect = 5e-04
Identities = 21/58 (36%), Positives = 36/58 (62%), Gaps = 2/58 (3%)
Query: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPD-GGWWEGEKEDGLRGWFPASYVQLLE 61
R R LY + G+ H + L F AG+ +T ++ D GW +G ++G G +PA+YV+ ++
Sbjct: 430 RVRALYDYEGQEHDE-LSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486
>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
Length = 591
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 33/154 (21%)
Query: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPD-GGWWEGEKEDGLRGWFPASYVQLLEKP 63
R R LY F E G+ + E+++L D GW EG G RG FPASYVQ++ P
Sbjct: 4 RARALYDFRSENPGE-ISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAP 62
Query: 64 GMVPP--------------PPGEESQTVILPP--------GWQSYLSPQGRRYYVNTTTN 101
P PPG + PP +Q+ L PQ
Sbjct: 63 EPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQ-------QAPP 115
Query: 102 ETTWERPSSSPGIPASPGSHRSSLPPTVNGYHAS 135
+T++ P + G P G+ + S GY AS
Sbjct: 116 PSTFQPPGA--GFPYGGGALQPSPQQLYGGYQAS 147
>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
Length = 624
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 33/154 (21%)
Query: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPD-GGWWEGEKEDGLRGWFPASYVQLLEKP 63
R R LY F E G+ + E+++L D GW EG G RG FPASYVQ++ P
Sbjct: 4 RARALYDFRSENPGE-ISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAP 62
Query: 64 GMVPP--------------PPGEESQTVILPP--------GWQSYLSPQGRRYYVNTTTN 101
P PPG + PP +Q+ L PQ
Sbjct: 63 EPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQ-------QAPP 115
Query: 102 ETTWERPSSSPGIPASPGSHRSSLPPTVNGYHAS 135
+T++ P + G P G+ + S GY AS
Sbjct: 116 PSTFQPPGA--GFPYGGGALQPSPQQLYGGYQAS 147
>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
Length = 628
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/154 (29%), Positives = 61/154 (39%), Gaps = 33/154 (21%)
Query: 5 RCRTLYPFSGERHGQGLRFAAGELITLLQVPD-GGWWEGEKEDGLRGWFPASYVQLLEKP 63
R R LY F E G+ + E+++L D GW EG G RG FPASYVQ++ P
Sbjct: 4 RARALYDFRSENPGE-ISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRAP 62
Query: 64 GMVPP--------------PPGEESQTVILPP--------GWQSYLSPQGRRYYVNTTTN 101
P PPG + PP +Q+ L PQ
Sbjct: 63 EPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQ-------QAPP 115
Query: 102 ETTWERPSSSPGIPASPGSHRSSLPPTVNGYHAS 135
+T++ P + G P G+ + S GY AS
Sbjct: 116 PSTFQPPGA--GFPYGGGALQPSPQQLYGGYQAS 147
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 48.9 bits (115), Expect = 1e-05
Identities = 58/241 (24%), Positives = 111/241 (46%), Gaps = 27/241 (11%)
Query: 225 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLA----KLSQNSLASQEEGSLGEAWAQVKK 280
Q+Q+K ++K SE+++ I E++ ++LA +L + ++ ++ E L +
Sbjct: 508 QEQMK-VALEKSQSEYLK--ISQEKEQQESLALEELELQKKAILTESENKL--------R 556
Query: 281 SLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKAR 340
L EAE + +L S +EK L +N KD+ H A+ K VEK +
Sbjct: 557 DLQQEAETYRTRILELESSLEKSLQE-NKNQSKDLAV--HLEAEKNKHNKEITVMVEKHK 613
Query: 341 KALTERQRDLE-MKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFE 399
L + + + T++L++ L + + +++K R K Q + L++ ++ QA E
Sbjct: 614 TELESLKHQQDALWTEKLQV-LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAH---IE 669
Query: 400 EMVTTTLELERLEVERVEMIRQHLCQYTQLRH----ETDMFNQSTVEPVDQLLRKVDPAK 455
EM TLE ++ +E + L + + RH E + T + +L K+D K
Sbjct: 670 EMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQK 729
Query: 456 D 456
+
Sbjct: 730 N 730
Score = 38.9 bits (89), Expect = 0.010
Identities = 43/209 (20%), Positives = 87/209 (41%), Gaps = 20/209 (9%)
Query: 264 ASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIA 323
A +E+ LG+ +++K L + H + L E ++ E K++ + +
Sbjct: 1935 AEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQER---EEKIKQEQEDLELKHN 1991
Query: 324 DLRKQLASRYASVEKARKALTERQRDLEM-------KTQQLEIKLSNKTEEDIKKARRKS 376
KQL + + L +++++LEM K Q++E +L +E+ + +K
Sbjct: 1992 STLKQLMREFNT------QLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKI 2045
Query: 377 TQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMF 436
+ DDL R Y + EEM +L+ ++E +++ Q +
Sbjct: 2046 AEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQ----TQLEELQKKYQQKLEQEENPGND 2101
Query: 437 NQSTVEPVDQLLRKVDPAKDRELWVREHK 465
N + +E QL +K D +L +E +
Sbjct: 2102 NVTIMELQTQLAQKTTLISDSKLKEQEFR 2130
Score = 37.4 bits (85), Expect = 0.030
Identities = 48/207 (23%), Positives = 85/207 (41%), Gaps = 31/207 (14%)
Query: 233 MQKEMSEFIRERIKIEEDYAKNLAKL-----SQNSLASQEEGSLGEAWAQVKKSLADEAE 287
+Q+++ E ++E KI++ + KL +L Q E G A+ K+ + + E
Sbjct: 319 LQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 288 VHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQ 347
+ + A+L S + K + E ++ +K S A+ E+ KAL+ Q
Sbjct: 379 MKEEEIAQLRSRI-KQMTTQGEELREQKEK-------------SERAAFEELEKALSTAQ 424
Query: 348 RDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQ----AQSKWFEEMVT 403
KT++ KL + +E IK + S + L + + Q K EE +
Sbjct: 425 -----KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA 479
Query: 404 TTLELERLEVERVEMIRQHLCQYTQLR 430
+L E+ R E Q L + Q R
Sbjct: 480 KLQKLHEKELARKE---QELTKKLQTR 503
Score = 36.6 bits (83), Expect = 0.051
Identities = 40/220 (18%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 221 ELLLQKQLKGKQMQKEMSEFIR------ERIKIEEDYAKNLAKLSQNSLASQEEGSLGEA 274
+L+ Q + + +M++++ + E E++ K + +N + EG E
Sbjct: 865 DLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEI 924
Query: 275 WAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYA 334
+K A E +H+ L+ E E N + +K +K L+K+L + A
Sbjct: 925 EILTQKLSAKEDSIHI-----LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEA 979
Query: 335 SVEK--ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLY-- 390
++K AL Q++ + + LE+ +N +R ++ Q + + +++
Sbjct: 980 KLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK-EQIESLTEVHRR 1038
Query: 391 --NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQ 428
N S W +++ EL+ + +++ Q + + Q
Sbjct: 1039 ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1078
Score = 35.0 bits (79), Expect = 0.15
Identities = 50/235 (21%), Positives = 90/235 (38%), Gaps = 42/235 (17%)
Query: 221 ELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKK 280
E+ L K LK +E + + ++ EED K S+ +E SL + + K
Sbjct: 1140 EVDLNKSLKENTFLQE--QLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1197
Query: 281 SLADEAEVHLKFSAKLHSEVE------KPLMNFREN------------FKKDMKKCDHHI 322
SL D++ K S +L +++ + L+ + N + C H
Sbjct: 1198 SLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRT 1257
Query: 323 ADLRKQLASRYASV---EKARKALTERQRDLEMKTQQLEIKLSNK--------------- 364
+++ L + +V E + LTE Q L + QQ +L K
Sbjct: 1258 TKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLV 1317
Query: 365 -TEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEM 418
+E ++K QA + C+ Q + + E + TL E L+ ++VE+
Sbjct: 1318 TEKEALQKEGGNQQQAASEKESCI---TQLKKELSENINAVTLMKEELKEKKVEI 1369
Score = 32.7 bits (73), Expect = 0.74
Identities = 47/213 (22%), Positives = 83/213 (38%), Gaps = 60/213 (28%)
Query: 221 ELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKK 280
E L KQ + + + E+SE ++ R K+EE+ + V K
Sbjct: 677 EKLDVKQTELESLSSELSEVLKARHKLEEELS-------------------------VLK 711
Query: 281 SLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKAR 340
D K+ E+E K D +K +HH + + S+++
Sbjct: 712 DQTD----------KMKQELEA---------KMDEQK-NHHQQQVDSIIKEHEVSIQRTE 751
Query: 341 KALTE---------RQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGD--DLMRCVDL 389
KAL + ++RD +K Q ++ E DIK++ + QA D+ +
Sbjct: 752 KALKDQINQLELLLKERDKHLKEHQAHVE---NLEADIKRSEGELQQASAKLDVFQSYQS 808
Query: 390 YNQAQSKWFEEMVTTTLE-LERLEVERVEMIRQ 421
Q+K +EE + + L LE ER+ + +Q
Sbjct: 809 ATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ 841
Score = 30.8 bits (68), Expect = 2.8
Identities = 33/176 (18%), Positives = 75/176 (42%), Gaps = 13/176 (7%)
Query: 302 KPLMNFRENFKKD---MKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLE 358
K L ++ K+ +K+C I ++Q + E ++ L ER ++LE K + L
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELE-KIKDLH 337
Query: 359 IKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERV-E 417
+ K ++ A+ Q D + A++K + TLE++ E+ ++
Sbjct: 338 MAEKTKLITQLRDAKNLIEQLEQDKGMVI-----AETK---RQMHETLEMKEEEIAQLRS 389
Query: 418 MIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVD 473
I+Q Q +LR + + ++ E +++ L ++ ++ I+ ++
Sbjct: 390 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE 445
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/179 (24%), Positives = 90/179 (50%), Gaps = 18/179 (10%)
Query: 229 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLS--QNSLASQEEGSLGEAWAQVKKSLADEA 286
+G++++ E+++ + ++++E D L S ++S +++ +L ++ L +E
Sbjct: 1263 EGERVRTELADKVT-KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321
Query: 287 EVHLKFSAKLHSEVEKPLMNFRE----------NFKKDMKKCDHHIADLRKQLASRYASV 336
L S KL +VE +FRE N +K + +AD++K++ +
Sbjct: 1322 RQKLSLSTKL-KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL 1380
Query: 337 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQS 395
E A + + Q+DLE +Q+ E K++ + ++K + + Q DDL+ VDL +Q QS
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVA--AYDKLEKTKTRLQQELDDLL--VDLDHQRQS 1435
Score = 40.8 bits (94), Expect = 0.003
Identities = 59/263 (22%), Positives = 109/263 (41%), Gaps = 43/263 (16%)
Query: 229 KGKQMQKEMSEFIRERIKIEEDYA-----KNLAKLSQNSLASQEEGSLGEAWAQVKKSLA 283
+ K+ +K++ E I+++E+ A K A+ ++ LA + S G+ +++
Sbjct: 1667 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR 1726
Query: 284 DEAEVHLKFSAKLHSEVEKPLMN---FRENFKKDMKKCDHHIADLRKQLASRYASVEKAR 340
EA + A+L E+E+ N + KK + D DL + S E AR
Sbjct: 1727 LEARI-----AQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE-RSHAQKNENAR 1780
Query: 341 KALTERQRDLEMKTQ----------------------QLEIKLSNKTEE---DIKKARRK 375
+ L + ++L++K Q QLE +L N+T+E K+ RR
Sbjct: 1781 QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRT 1840
Query: 376 STQAGDDLMRCVD-LYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETD 434
+ D L++ D N Q K + +T L+ + ++E E Q + R +
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ---RANASRRKLQ 1897
Query: 435 MFNQSTVEPVDQLLRKVDPAKDR 457
+ E D + R+V K++
Sbjct: 1898 RELEDATETADAMNREVSSLKNK 1920
Score = 38.9 bits (89), Expect = 0.010
Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 37/214 (17%)
Query: 229 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSL-ASQEEGSLGEAWAQVKKSLADEAE 287
K + M ++ E +R K ++ K KL +S S + L A++K LA + E
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 288 VHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKA----- 342
A++ E + M K +++ + I++L++ L S AS KA K
Sbjct: 1084 ELQAALARVEEEAAQKNMAL-----KKIRELESQISELQEDLESERASRNKAEKQKRDLG 1138
Query: 343 ---------------LTERQRDLEMKTQQLEIKLSNKT--------EEDIKKARRKSTQA 379
T Q++L K +Q E+ + KT E I++ R+K +QA
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQ-EVNILKKTLEEEAKTHEAQIQEMRQKHSQA 1197
Query: 380 GDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEV 413
++L ++ + ++ E TLE ER E+
Sbjct: 1198 VEELAEQLEQTKRVKANL--EKAKQTLENERGEL 1229
Score = 37.0 bits (84), Expect = 0.039
Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 22/159 (13%)
Query: 263 LASQEEGSLGEAWAQVK---KSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 319
++ QEE + + VK K LA AE L L S++ + +E + + + C
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLA--AENRLTEMETLQSQLMAEKLQLQEQLQAETELC- 896
Query: 320 HHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTE--EDIKKARRKST 377
A E+ R LT ++++LE LE ++ + E + ++ ++K
Sbjct: 897 --------------AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 378 QAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERV 416
Q +L ++ A+ K E VTT +L++LE E++
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQI 981
Score = 30.0 bits (66), Expect = 4.8
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 246 KIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLM 305
K ++ + + LA+ S EE EA A+ K++ A L+ + + +E+E+
Sbjct: 1441 KKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNK 1500
Query: 306 NFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKT 365
FR + M D D+ K + +EK+++AL Q+ EMKTQ E++ +
Sbjct: 1501 QFRTEMEDLMSSKD----DVGKSVHE----LEKSKRAL--EQQVEEMKTQLEELEDELQA 1550
Query: 366 EEDIKKARRKSTQA 379
ED K + QA
Sbjct: 1551 TEDAKLRLEVNLQA 1564
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 48.5 bits (114), Expect = 1e-05
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 24/221 (10%)
Query: 229 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEV 288
K K + M + R+K EE + L KL + EG + Q+ A AE+
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL-----EGDASDFHEQIADLQAQIAEL 1081
Query: 289 HLKFSAKLHSEVEKPLMNF------RENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 342
++ AK E++ L + N K +++ + HI+DL++ L S A+ KA K
Sbjct: 1082 KMQL-AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 343 LTERQRDLEMKTQQLEIKL-SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEM 401
+ +LE +LE L S T+++++ R + L + +D ++ +EM
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM 1197
Query: 402 VTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVE 442
+ + VE + + L Q+ + + D N+ T+E
Sbjct: 1198 -------RQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLE 1230
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Query: 231 KQMQKEMSEFIRERIKIEEDYAKNLA----KLSQNSLASQEEGSLGEAWAQVKKSLADEA 286
KQ +E+ + R++ EED + L K++Q L +E+ EA Q + A
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 976
Query: 287 EVHLKFSAKLHSEVEKPLMNFREN-FKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 345
E +K KL E+ +M+ + N K+ K + I+DL LA E+ K LT+
Sbjct: 977 EAKIK---KLEDEIL--VMDDQNNKLSKERKLLEERISDLTTNLAEE----EEKAKNLTK 1027
Query: 346 RQRDLEMKTQQLEIKL--SNKTEEDIKKARRK 375
+ E +LE++L K+ ++++K +RK
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Score = 38.1 bits (87), Expect = 0.018
Identities = 42/203 (20%), Positives = 85/203 (41%), Gaps = 21/203 (10%)
Query: 266 QEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADL 325
+EE E Q K +AE LK + HS++ + +E + + +
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL-------- 902
Query: 326 RKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTE--EDIKKARRKSTQAGDDL 383
YA E+ R L ++++LE ++E +L + + + ++ R+K Q DL
Sbjct: 903 -------YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 384 MRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEP 443
++ A+ K E VT ++++LE E + M Q+ +L E + + +
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN----NKLSKERKLLEERISDL 1011
Query: 444 VDQLLRKVDPAKDRELWVREHKT 466
L + + AK+ +H++
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHES 1034
Score = 32.7 bits (73), Expect = 0.74
Identities = 36/182 (19%), Positives = 75/182 (41%), Gaps = 23/182 (12%)
Query: 225 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA-------- 276
Q L+ +++ +E++ + R ++++ + A+++Q +EE EA +
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 277 ---QVKKSLADEAEVHLKFSA----------KLHSEVEKPLMNFRENFKKDMKKCDHHIA 323
Q+ LA E K + +L S++ + + FK + + IA
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 324 DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDL 383
L +Q+ + A K+L +Q+D ++K L+++ K E K+ K L
Sbjct: 1825 QLEEQVEQEAREKQAATKSL--KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 384 MR 385
R
Sbjct: 1883 KR 1884
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,912,730
Number of Sequences: 37866
Number of extensions: 1133390
Number of successful extensions: 6567
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 627
Number of HSP's that attempted gapping in prelim test: 5331
Number of HSP's gapped (non-prelim): 1770
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.