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Search of human proteins with 41406076
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
(336 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens] 676 0.0
gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens] 643 0.0
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 643 0.0
gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens] 643 0.0
gi|20149528 proline-serine-threonine phosphatase interacting pro... 92 9e-19
gi|239049457 FCH domain only 1 isoform b [Homo sapiens] 88 1e-17
gi|29789054 FCH domain only 1 isoform b [Homo sapiens] 88 1e-17
gi|239049440 FCH domain only 1 isoform a [Homo sapiens] 88 1e-17
gi|165905601 proline-serine-threonine phosphatase interacting pr... 83 4e-16
gi|226371723 FCH domain only 2 isoform a [Homo sapiens] 79 4e-15
gi|226371725 FCH domain only 2 isoform b [Homo sapiens] 77 2e-14
gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo sap... 72 7e-13
gi|38524622 formin binding protein 1 [Homo sapiens] 57 3e-08
gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens] 55 9e-08
gi|239049540 FCH domain only 1 isoform c [Homo sapiens] 54 2e-07
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 51 1e-06
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 51 1e-06
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 51 1e-06
gi|148747351 protein kinase C and casein kinase substrate in neu... 51 2e-06
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 49 6e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 49 8e-06
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 49 8e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 49 8e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 49 8e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 49 8e-06
gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo sap... 48 1e-05
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 47 2e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 47 2e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 47 2e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 47 2e-05
>gi|41406076 growth arrest-specific 7 isoform a [Homo sapiens]
Length = 336
Score = 676 bits (1744), Expect = 0.0
Identities = 336/336 (100%), Positives = 336/336 (100%)
Query: 1 MSNMENSFDDVSCLSPQNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSY 60
MSNMENSFDDVSCLSPQNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSY
Sbjct: 1 MSNMENSFDDVSCLSPQNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSY 60
Query: 61 CDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQ 120
CDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQ
Sbjct: 61 CDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQ 120
Query: 121 NSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDH 180
NSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDH
Sbjct: 121 NSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDH 180
Query: 181 HIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAG 240
HIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAG
Sbjct: 181 HIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAG 240
Query: 241 DDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQST 300
DDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQST
Sbjct: 241 DDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQST 300
Query: 301 VEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 336
VEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI
Sbjct: 301 VEPVDQLLRKVDPAKDRELWVREHKTGNIRPVDMEI 336
>gi|195546919 growth arrest-specific 7 isoform d [Homo sapiens]
Length = 412
Score = 643 bits (1659), Expect = 0.0
Identities = 320/320 (100%), Positives = 320/320 (100%)
Query: 17 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 76
QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT
Sbjct: 93 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 152
Query: 77 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 136
VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA
Sbjct: 153 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 212
Query: 137 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 196
QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV
Sbjct: 213 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 272
Query: 197 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 256
EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK
Sbjct: 273 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 332
Query: 257 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 316
WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD
Sbjct: 333 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 392
Query: 317 RELWVREHKTGNIRPVDMEI 336
RELWVREHKTGNIRPVDMEI
Sbjct: 393 RELWVREHKTGNIRPVDMEI 412
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 643 bits (1659), Expect = 0.0
Identities = 320/320 (100%), Positives = 320/320 (100%)
Query: 17 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 76
QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT
Sbjct: 157 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 216
Query: 77 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 136
VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA
Sbjct: 217 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 276
Query: 137 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 196
QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV
Sbjct: 277 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 336
Query: 197 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 256
EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK
Sbjct: 337 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 396
Query: 257 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 316
WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD
Sbjct: 397 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 456
Query: 317 RELWVREHKTGNIRPVDMEI 336
RELWVREHKTGNIRPVDMEI
Sbjct: 457 RELWVREHKTGNIRPVDMEI 476
>gi|41406078 growth arrest-specific 7 isoform b [Homo sapiens]
Length = 416
Score = 643 bits (1659), Expect = 0.0
Identities = 320/320 (100%), Positives = 320/320 (100%)
Query: 17 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 76
QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT
Sbjct: 97 QNLGSSSPSKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGT 156
Query: 77 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 136
VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA
Sbjct: 157 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA 216
Query: 137 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 196
QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV
Sbjct: 217 QVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASV 276
Query: 197 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 256
EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK
Sbjct: 277 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSK 336
Query: 257 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 316
WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD
Sbjct: 337 WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKD 396
Query: 317 RELWVREHKTGNIRPVDMEI 336
RELWVREHKTGNIRPVDMEI
Sbjct: 397 RELWVREHKTGNIRPVDMEI 416
>gi|20149528 proline-serine-threonine phosphatase interacting
protein 1 [Homo sapiens]
Length = 416
Score = 91.7 bits (226), Expect = 9e-19
Identities = 62/260 (23%), Positives = 125/260 (48%), Gaps = 8/260 (3%)
Query: 79 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQV 138
G+E+LLQ+ L G++M K+M E +R+R + EE Y K L ++++ + E SL ++ +
Sbjct: 21 GYEVLLQRLLDGRKMCKDMEELLRQRAQAEERYGKELVQIARKAGGQTEINSLRASFDSL 80
Query: 139 KKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEK 198
K+ + + H++ + L E+ + L FRE K+ KK + + ++K S Y +
Sbjct: 81 KQQMENVGSSHIQLALTLREEL-RSLEEFRERQKEQRKKYEAVMDRVQKSKLSLYKKAME 139
Query: 199 ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQA----- 253
++K ++ RD + Q E +N ++ ++K++ K+ Q D +Y Q+
Sbjct: 140 SKKTYEQKCRDADDAEQAFERISANGHQKQVEKSQNKARQCKDSATEAERVYRQSIAQLE 199
Query: 254 --QSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKV 311
+++W +E TT + E +R+ ++R L ++ + + E V L
Sbjct: 200 KVRAEWEQEHRTTCEAFQLQEFDRLTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGC 259
Query: 312 DPAKDRELWVREHKTGNIRP 331
D + +++ TG P
Sbjct: 260 SIDADIDSFIQAKSTGTEPP 279
>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 87.8 bits (216), Expect = 1e-17
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 62 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 121
++FW +K GFE+L +G KE+++FIRER IEE Y+K +AKLS+
Sbjct: 6 EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
Query: 122 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 181
+ G+ W + S A HL+ + KL ++ K ++ + E K KKC
Sbjct: 58 ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
Query: 182 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 238
+ D + L+ + K+R+ R D E ++ + +++++ KA K+ +
Sbjct: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
Query: 239 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 293
A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y +T
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 294 ---DMFNQSTVE-PVDQLLRKVDPAK 315
+ F Q+ V+ LLRK +K
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
Length = 889
Score = 87.8 bits (216), Expect = 1e-17
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 62 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 121
++FW +K GFE+L +G KE+++FIRER IEE Y+K +AKLS+
Sbjct: 6 EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
Query: 122 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 181
+ G+ W + S A HL+ + KL ++ K ++ + E K KKC
Sbjct: 58 ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
Query: 182 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 238
+ D + L+ + K+R+ R D E ++ + +++++ KA K+ +
Sbjct: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
Query: 239 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 293
A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y +T
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 294 ---DMFNQSTVE-PVDQLLRKVDPAK 315
+ F Q+ V+ LLRK +K
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
Length = 891
Score = 87.8 bits (216), Expect = 1e-17
Identities = 69/266 (25%), Positives = 125/266 (46%), Gaps = 27/266 (10%)
Query: 62 DYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN 121
++FW +K GFE+L +G KE+++FIRER IEE Y+K +AKLS+
Sbjct: 6 EHFWGEKNH--------GFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKL 57
Query: 122 SLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHH 181
+ G+ W + S A HL+ + KL ++ K ++ + E K KKC
Sbjct: 58 ASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKTHKKCKEE 116
Query: 182 IA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQ 238
+ D + L+ + K+R+ R D E ++ + +++++ KA K+ +
Sbjct: 117 VVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDKAETKTKK 170
Query: 239 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHET----- 293
A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y +T
Sbjct: 171 AAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQIG 230
Query: 294 ---DMFNQSTVE-PVDQLLRKVDPAK 315
+ F Q+ V+ LLRK +K
Sbjct: 231 QVHEEFKQNIENVSVEMLLRKFAESK 256
>gi|165905601 proline-serine-threonine phosphatase interacting
protein 2 [Homo sapiens]
Length = 334
Score = 82.8 bits (203), Expect = 4e-16
Identities = 65/261 (24%), Positives = 116/261 (44%), Gaps = 9/261 (3%)
Query: 79 GFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE-GSLGEAWAQ 137
G++ ++Q G++ KE +F++ER IEE Y K+L LS+ Q E +L A
Sbjct: 20 GYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKRALEV 79
Query: 138 VKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVE 197
K+ + + A+ H++ + L E K + FRE K KK + + + KQ + ++
Sbjct: 80 FKQQVDNVAQCHIQLAQSLREEARK-MEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTM 138
Query: 198 KARKALTERQRDLEMKTQQL--EIKLSNKTEED---IKKARRKSTQAGDD--LMRCVDLY 250
A+K ++ RD + Q + L N +++ +K A K+ D M +
Sbjct: 139 DAKKNYEQKCRDKDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTL 198
Query: 251 NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRK 310
++ + +W E + E E ER+ R L + + + + E V + L
Sbjct: 199 DKVREEWQSEHIKACEAFEAQECERINFFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEM 258
Query: 311 VDPAKDRELWVREHKTGNIRP 331
+D E +V + KTG I P
Sbjct: 259 CSIQRDIEYFVNQRKTGQIPP 279
>gi|226371723 FCH domain only 2 isoform a [Homo sapiens]
Length = 810
Score = 79.3 bits (194), Expect = 4e-15
Identities = 55/223 (24%), Positives = 107/223 (47%), Gaps = 14/223 (6%)
Query: 60 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 119
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
Query: 120 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
Query: 180 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 238
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
Query: 239 AGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQ 281
A D V+ Y A++ + ++M T + + +E + I++
Sbjct: 173 ATDTYKLYVEKYALAKADFEQKMTETAQKFQDIEETHLIHIKE 215
>gi|226371725 FCH domain only 2 isoform b [Homo sapiens]
Length = 777
Score = 77.4 bits (189), Expect = 2e-14
Identities = 55/210 (26%), Positives = 102/210 (48%), Gaps = 15/210 (7%)
Query: 60 YCDYFWADKKDPQGNGTVAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLS 119
+ + FW +K +GF++L G+ KE+++F+RER IEE Y++++ KL+
Sbjct: 6 FVENFWGEKN--------SGFDVLYHNMKHGQISTKELADFVRERATIEEAYSRSMTKLA 57
Query: 120 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
+++ + G+ W K S A HL KL E+ K + + E K KK
Sbjct: 58 KSASNYSQLGTFAPVWDVFKTSTEKLANCHLDLVRKL-QELIKEVQKYGEEQVKSHKKTK 116
Query: 180 HHIADLRKQLASRYASVEKARKALTERQRDLEMK-TQQLEIKLSNKTEEDIKKARRKSTQ 238
+A + + +++ +AL + + + K +Q +K T+ +I+KA KS +
Sbjct: 117 EEVAGTLEAV----QTIQSITQALQKSKENYNAKCVEQERLKKEGATQREIEKAAVKSKK 172
Query: 239 AGDDLMRCVDLYNQAQSKWFEEMVTTTLEL 268
A D V+ Y A++ FE+ +T T ++
Sbjct: 173 ATDTYKLYVEKYALAKAD-FEQKMTETAQV 201
>gi|89886447 nitric oxide synthase trafficker isoform 2 [Homo
sapiens]
Length = 506
Score = 72.0 bits (175), Expect = 7e-13
Identities = 57/247 (23%), Positives = 108/247 (43%), Gaps = 16/247 (6%)
Query: 90 GKQMQKEMSEFIRERIKIEEDYAKNLAKLSQN---SLASQEEGSLGEAWAQVKKSLADEA 146
G+ K+++ +++R +E YAK L KL+ +L + + + AWA + + A
Sbjct: 24 GENFCKQVTSVLQQRANLEISYAKGLQKLASKLSKALQNTRKSCVSSAWAWASEGMKSTA 83
Query: 147 EVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTER 206
++H K + E KP +K K D+ + + S + KA+K L
Sbjct: 84 DLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMVS 143
Query: 207 QRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQ-------AQSKWFE 259
+ E Q +E + TE++ +K K T++ + L + + Y Q + KW
Sbjct: 144 TKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWEN 203
Query: 260 EMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQL---LRKVDPAKD 316
+ + LE ER++++ +L QY+Q +F Q+ Q+ + K+D KD
Sbjct: 204 TLENCYQSILELEKERIQLLCNNLNQYSQ---HISLFGQTLTTCHTQIHCAISKIDIEKD 260
Query: 317 RELWVRE 323
+ + E
Sbjct: 261 IQAVMEE 267
>gi|38524622 formin binding protein 1 [Homo sapiens]
Length = 617
Score = 56.6 bits (135), Expect = 3e-08
Identities = 56/268 (20%), Positives = 112/268 (41%), Gaps = 27/268 (10%)
Query: 90 GKQMQKEMSEFIRERIKIEEDYAK---NLAKLSQNSLASQEEGSLG----EAWAQVKKSL 142
G + ++ +F++ER +IE YAK NL+K Q S+EE +A+ +
Sbjct: 21 GIDILEKYIKFVKERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYKYTSCKAFISNLNEM 80
Query: 143 ADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMK-------KCDHHIADLRKQLASRYAS 195
D A H S + S++ L + + K++ K K HI KQL S
Sbjct: 81 NDYAGQHEVISENMASQIIVDLARYVQELKQERKSNFHDGRKAQQHIETCWKQLESSKRR 140
Query: 196 VEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRK-------STQAGDDLMRCVD 248
E+ K Q+ E + N T+ D++KAR++ + + D +
Sbjct: 141 FERDCKEADRAQQYFEKMDADI-----NVTKADVEKARQQAQIRHQMAEDSKADYSSILQ 195
Query: 249 LYNQAQSKWFEEMVTTTLE-LERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQL 307
+N Q +++ + + ++ +E R+ + + + Y ++ + ++ + +
Sbjct: 196 KFNHEQHEYYHTHIPNIFQKIQEMEERRIVRMGESMKTYAEVDRQVIPIIGKCLDGIVKA 255
Query: 308 LRKVDPAKDRELWVREHKTGNIRPVDME 335
+D D +L + +K+G P D+E
Sbjct: 256 AESIDQKNDSQLVIEAYKSGFEPPGDIE 283
>gi|11342676 thyroid hormone receptor interactor 10 [Homo sapiens]
Length = 545
Score = 55.1 bits (131), Expect = 9e-08
Identities = 55/274 (20%), Positives = 118/274 (43%), Gaps = 19/274 (6%)
Query: 80 FELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLAS-------QEEGSLG 132
FE+L + G + +F++ER ++E+ YAK L L + L + + S
Sbjct: 11 FEVLERHTQWGLDLLDRYVKFVKERTEVEQAYAKQLRSLVKKYLPKRPAKDDPESKFSQQ 70
Query: 133 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASR 192
+++ Q+ + + D A + L V L + + K++ K ++QL +
Sbjct: 71 QSFVQILQEVNDFAGQRELVAENLSVRVCLELTKYSQEMKQERKMHFQEGRRAQQQLENG 130
Query: 193 YASVEKARKALTERQRDLEMKTQQLEIKLS---NKTEEDIKKARRK-------STQAGDD 242
+ +E +++ R+ E Q E +L N T+ D++KA+++ + ++ ++
Sbjct: 131 FKQLENSKRKFERDCREAEKAAQTAE-RLDQDINATKADVEKAKQQAHLRSHMAEESKNE 189
Query: 243 LMRCVDLYNQAQSK-WFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTV 301
+ +N+ Q+ +F +M +L+ ++ R + ++ E +
Sbjct: 190 YAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELEVVPIIAKCL 249
Query: 302 EPVDQLLRKVDPAKDRELWVREHKTGNIRPVDME 335
E + VDP D + + HK+G RP D+E
Sbjct: 250 EGMKVAANAVDPKNDSHVLIELHKSGFARPGDVE 283
>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
Length = 839
Score = 53.9 bits (128), Expect = 2e-07
Identities = 49/213 (23%), Positives = 96/213 (45%), Gaps = 19/213 (8%)
Query: 115 LAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKD 174
+AKLS+ + G+ W + S A HL+ + KL ++ K ++ + E K
Sbjct: 1 MAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKL-QDLIKDVLRYGEEQLKT 59
Query: 175 MKKCDHHIA---DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKK 231
KKC + D + L+ + K+R+ R D E ++ + +++++ K
Sbjct: 60 HKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMDQE------RLRRESTSQKEMDK 113
Query: 232 ARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRH 291
A K+ +A + L R V+ YN A++ + ++M+ + L + +E + ++ L Y
Sbjct: 114 AETKTKKAAESLRRSVEKYNSARADFEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVE 173
Query: 292 ET--------DMFNQSTVE-PVDQLLRKVDPAK 315
+T + F Q+ V+ LLRK +K
Sbjct: 174 DTHVQIGQVHEEFKQNIENVSVEMLLRKFAESK 206
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/229 (20%), Positives = 113/229 (49%), Gaps = 37/229 (16%)
Query: 88 LKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEG-SLGEAWAQVKKSLADEA 146
+K ++M ++ +RE + +ED + + L + LA+Q E S+ + +++ +A++
Sbjct: 295 IKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKD 354
Query: 147 EVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTER 206
+H + K + ++++ L + ++ ++K + + ++ +LA R A++ KA ER
Sbjct: 355 SMHRQTEDK-NRQLQERLELAEQKLQQTLRKAE-TLPEVEAELAQRVAALSKAE----ER 408
Query: 207 QRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTL 266
++E + +Q+E +L K +E +++AR++ + N+ +K + V
Sbjct: 409 HGNIEERLRQMEAQLEEKNQE-LQRARQR------------EKMNEEHNKRLSDTV---- 451
Query: 267 ELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAK 315
++L E E ++ HL + + +E + LLR+V+ AK
Sbjct: 452 --DKLLSESNERLQLHLKE-----------RMAALEDKNSLLREVESAK 487
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 51.2 bits (121), Expect = 1e-06
Identities = 48/229 (20%), Positives = 113/229 (49%), Gaps = 37/229 (16%)
Query: 88 LKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEG-SLGEAWAQVKKSLADEA 146
+K ++M ++ +RE + +ED + + L + LA+Q E S+ + +++ +A++
Sbjct: 295 IKSEEMNTKLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSVHDLNDKLENEIANKD 354
Query: 147 EVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTER 206
+H + K + ++++ L + ++ ++K + + ++ +LA R A++ KA ER
Sbjct: 355 SMHRQTEDK-NRQLQERLELAEQKLQQTLRKAE-TLPEVEAELAQRVAALSKAE----ER 408
Query: 207 QRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTL 266
++E + +Q+E +L K +E +++AR++ + N+ +K + V
Sbjct: 409 HGNIEERLRQMEAQLEEKNQE-LQRARQR------------EKMNEEHNKRLSDTV---- 451
Query: 267 ELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAK 315
++L E E ++ HL + + +E + LLR+V+ AK
Sbjct: 452 --DKLLSESNERLQLHLKE-----------RMAALEDKNSLLREVESAK 487
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 51.2 bits (121), Expect = 1e-06
Identities = 45/230 (19%), Positives = 110/230 (47%), Gaps = 9/230 (3%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEG-SLGEAWAQVKKSLADEAE 147
K ++ ++ ++E + ED + + L + L++Q E SL +A +++ LA +
Sbjct: 279 KAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKES 338
Query: 148 VHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQ 207
++ + K E L + ++ ++ ++K + + ++ QLA R A++ KA ER
Sbjct: 339 LYRQSEEKSRQLAEW-LDDAKQKLQQTLQKAET-LPEIEAQLAQRVAALNKAE----ERH 392
Query: 208 RDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLE 267
+ E + +QLE +L K +E +++AR++ D R + ++ S+ E + L+
Sbjct: 393 GNFEERLRQLEAQLEEKNQE-LQRARQREKMNDDHNKRLSETVDKLLSE-SNERLQLHLK 450
Query: 268 LERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDR 317
+E + + + +L+ E + + + ++++ ++D + R
Sbjct: 451 ERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGR 500
>gi|148747351 protein kinase C and casein kinase substrate in
neurons 2 [Homo sapiens]
Length = 486
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/276 (19%), Positives = 119/276 (43%), Gaps = 28/276 (10%)
Query: 77 VAGFELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEE----GSLG 132
V ++ +++ G ++ ++ + ER +IE+ YA+ L + ++ E+ G++
Sbjct: 21 VGNYKRTVKRIDDGHRLCSDLMNCLHERARIEKAYAQQLTEWARRWRQLVEKGPQYGTVE 80
Query: 133 EAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNF-RENFKKDM-------KKCDHHIAD 184
+AW +E+HL+ A L ++ + + N+ +E F K M K+ +
Sbjct: 81 KAWMAFMSEAERVSELHLEVKASLMNDDFEKIKNWQKEAFHKQMMGGFKETKEAEDGFRK 140
Query: 185 LRKQLASRYASVEKARKA--LTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDD 242
+K A + VE A+KA ++ L + + + E +KK + K + D
Sbjct: 141 AQKPWAKKLKEVEAAKKAHHAACKEEKLAISREANSKADPSLNPEQLKKLQDKIEKCKQD 200
Query: 243 LMRCVDLY-------NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDM 295
+++ + Y +Q ++ E M + ++ E +R+ R+ L +++ D+
Sbjct: 201 VLKTKEKYEKSLKELDQGTPQYMENMEQVFEQCQQFEEKRLRFFREVL---LEVQKHLDL 257
Query: 296 FN----QSTVEPVDQLLRKVDPAKDRELWVREHKTG 327
N ++ ++Q +R D +D + H G
Sbjct: 258 SNVAGYKAIYHDLEQSIRAADAVEDLRWFRANHGPG 293
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 48.9 bits (115), Expect = 6e-06
Identities = 58/241 (24%), Positives = 111/241 (46%), Gaps = 27/241 (11%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLA----KLSQNSLASQEEGSLGEAWAQVKK 140
Q+Q+K ++K SE+++ I E++ ++LA +L + ++ ++ E L +
Sbjct: 508 QEQMK-VALEKSQSEYLK--ISQEKEQQESLALEELELQKKAILTESENKL--------R 556
Query: 141 SLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKAR 200
L EAE + +L S +EK L +N KD+ H A+ K VEK +
Sbjct: 557 DLQQEAETYRTRILELESSLEKSLQE-NKNQSKDLAV--HLEAEKNKHNKEITVMVEKHK 613
Query: 201 KALTERQRDLE-MKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFE 259
L + + + T++L++ L + + +++K R K Q + L++ ++ QA E
Sbjct: 614 TELESLKHQQDALWTEKLQV-LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAH---IE 669
Query: 260 EMVTTTLELERLEVERVEMIRQHLCQYTQLRH----ETDMFNQSTVEPVDQLLRKVDPAK 315
EM TLE ++ +E + L + + RH E + T + +L K+D K
Sbjct: 670 EMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQK 729
Query: 316 D 316
+
Sbjct: 730 N 730
Score = 38.9 bits (89), Expect = 0.007
Identities = 43/209 (20%), Positives = 87/209 (41%), Gaps = 20/209 (9%)
Query: 124 ASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIA 183
A +E+ LG+ +++K L + H + L E ++ E K++ + +
Sbjct: 1935 AEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQER---EEKIKQEQEDLELKHN 1991
Query: 184 DLRKQLASRYASVEKARKALTERQRDLEM-------KTQQLEIKLSNKTEEDIKKARRKS 236
KQL + + L +++++LEM K Q++E +L +E+ + +K
Sbjct: 1992 STLKQLMREFNT------QLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKI 2045
Query: 237 TQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMF 296
+ DDL R Y + EEM +L+ ++E +++ Q +
Sbjct: 2046 AEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQ----TQLEELQKKYQQKLEQEENPGND 2101
Query: 297 NQSTVEPVDQLLRKVDPAKDRELWVREHK 325
N + +E QL +K D +L +E +
Sbjct: 2102 NVTIMELQTQLAQKTTLISDSKLKEQEFR 2130
Score = 37.4 bits (85), Expect = 0.019
Identities = 48/207 (23%), Positives = 85/207 (41%), Gaps = 31/207 (14%)
Query: 93 MQKEMSEFIRERIKIEEDYAKNLAKL-----SQNSLASQEEGSLGEAWAQVKKSLADEAE 147
+Q+++ E ++E KI++ + KL +L Q E G A+ K+ + + E
Sbjct: 319 LQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 148 VHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQ 207
+ + A+L S + K + E ++ +K S A+ E+ KAL+ Q
Sbjct: 379 MKEEEIAQLRSRI-KQMTTQGEELREQKEK-------------SERAAFEELEKALSTAQ 424
Query: 208 RDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQ----AQSKWFEEMVT 263
KT++ KL + +E IK + S + L + + Q K EE +
Sbjct: 425 -----KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA 479
Query: 264 TTLELERLEVERVEMIRQHLCQYTQLR 290
+L E+ R E Q L + Q R
Sbjct: 480 KLQKLHEKELARKE---QELTKKLQTR 503
Score = 36.6 bits (83), Expect = 0.033
Identities = 40/220 (18%), Positives = 91/220 (41%), Gaps = 18/220 (8%)
Query: 81 ELLLQKQLKGKQMQKEMSEFIR------ERIKIEEDYAKNLAKLSQNSLASQEEGSLGEA 134
+L+ Q + + +M++++ + E E++ K + +N + EG E
Sbjct: 865 DLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEI 924
Query: 135 WAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYA 194
+K A E +H+ L+ E E N + +K +K L+K+L + A
Sbjct: 925 EILTQKLSAKEDSIHI-----LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEA 979
Query: 195 SVEK--ARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLY-- 250
++K AL Q++ + + LE+ +N +R ++ Q + + +++
Sbjct: 980 KLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK-EQIESLTEVHRR 1038
Query: 251 --NQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQ 288
N S W +++ EL+ + +++ Q + + Q
Sbjct: 1039 ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1078
Score = 35.0 bits (79), Expect = 0.095
Identities = 50/235 (21%), Positives = 90/235 (38%), Gaps = 42/235 (17%)
Query: 81 ELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKK 140
E+ L K LK +E + + ++ EED K S+ +E SL + + K
Sbjct: 1140 EVDLNKSLKENTFLQE--QLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1197
Query: 141 SLADEAEVHLKFSAKLHSEVE------KPLMNFREN------------FKKDMKKCDHHI 182
SL D++ K S +L +++ + L+ + N + C H
Sbjct: 1198 SLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRT 1257
Query: 183 ADLRKQLASRYASV---EKARKALTERQRDLEMKTQQLEIKLSNK--------------- 224
+++ L + +V E + LTE Q L + QQ +L K
Sbjct: 1258 TKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLV 1317
Query: 225 -TEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEM 278
+E ++K QA + C+ Q + + E + TL E L+ ++VE+
Sbjct: 1318 TEKEALQKEGGNQQQAASEKESCI---TQLKKELSENINAVTLMKEELKEKKVEI 1369
Score = 32.7 bits (73), Expect = 0.47
Identities = 47/213 (22%), Positives = 83/213 (38%), Gaps = 60/213 (28%)
Query: 81 ELLLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKK 140
E L KQ + + + E+SE ++ R K+EE+ + V K
Sbjct: 677 EKLDVKQTELESLSSELSEVLKARHKLEEELS-------------------------VLK 711
Query: 141 SLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKAR 200
D K+ E+E K D +K +HH + + S+++
Sbjct: 712 DQTD----------KMKQELEA---------KMDEQK-NHHQQQVDSIIKEHEVSIQRTE 751
Query: 201 KALTE---------RQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGD--DLMRCVDL 249
KAL + ++RD +K Q ++ E DIK++ + QA D+ +
Sbjct: 752 KALKDQINQLELLLKERDKHLKEHQAHVE---NLEADIKRSEGELQQASAKLDVFQSYQS 808
Query: 250 YNQAQSKWFEEMVTTTLE-LERLEVERVEMIRQ 281
Q+K +EE + + L LE ER+ + +Q
Sbjct: 809 ATHEQTKAYEEQLAQLQQKLLDLETERILLTKQ 841
Score = 30.8 bits (68), Expect = 1.8
Identities = 33/176 (18%), Positives = 75/176 (42%), Gaps = 13/176 (7%)
Query: 162 KPLMNFRENFKKD---MKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLE 218
K L ++ K+ +K+C I ++Q + E ++ L ER ++LE K + L
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELE-KIKDLH 337
Query: 219 IKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERV-E 277
+ K ++ A+ Q D + A++K + TLE++ E+ ++
Sbjct: 338 MAEKTKLITQLRDAKNLIEQLEQDKGMVI-----AETK---RQMHETLEMKEEEIAQLRS 389
Query: 278 MIRQHLCQYTQLRHETDMFNQSTVEPVDQLLRKVDPAKDRELWVREHKTGNIRPVD 333
I+Q Q +LR + + ++ E +++ L ++ ++ I+ ++
Sbjct: 390 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE 445
Score = 28.5 bits (62), Expect = 8.9
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 13/135 (9%)
Query: 184 DLRKQLASRYASVEKARKALTERQRDLEM--KTQQLEIKLSNKTEEDIKKARRKSTQAGD 241
DL +LA +K K + Q+DL M K Q E+++ K + ++ + K Q
Sbjct: 1927 DLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDL 1986
Query: 242 DLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTV 301
+L +N + E T +L + E E I++ + + ++ E +S
Sbjct: 1987 ELK-----HNSTLKQLMREFNT---QLAQKEQELEMTIKETINKAQEVEAE---LLESHQ 2035
Query: 302 EPVDQLLRKVDPAKD 316
E +QLL+K+ D
Sbjct: 2036 EETNQLLKKIAEKDD 2050
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.5 bits (114), Expect = 8e-06
Identities = 44/179 (24%), Positives = 90/179 (50%), Gaps = 18/179 (10%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLS--QNSLASQEEGSLGEAWAQVKKSLADEA 146
+G++++ E+++ + ++++E D L S ++S +++ +L ++ L +E
Sbjct: 1263 EGERVRTELADKVT-KLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEEN 1321
Query: 147 EVHLKFSAKLHSEVEKPLMNFRE----------NFKKDMKKCDHHIADLRKQLASRYASV 196
L S KL +VE +FRE N +K + +AD++K++ +
Sbjct: 1322 RQKLSLSTKL-KQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCL 1380
Query: 197 EKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQS 255
E A + + Q+DLE +Q+ E K++ + ++K + + Q DDL+ VDL +Q QS
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVA--AYDKLEKTKTRLQQELDDLL--VDLDHQRQS 1435
Score = 40.8 bits (94), Expect = 0.002
Identities = 59/263 (22%), Positives = 109/263 (41%), Gaps = 43/263 (16%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYA-----KNLAKLSQNSLASQEEGSLGEAWAQVKKSLA 143
+ K+ +K++ E I+++E+ A K A+ ++ LA + S G+ +++
Sbjct: 1667 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR 1726
Query: 144 DEAEVHLKFSAKLHSEVEKPLMN---FRENFKKDMKKCDHHIADLRKQLASRYASVEKAR 200
EA + A+L E+E+ N + KK + D DL + S E AR
Sbjct: 1727 LEARI-----AQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLE-RSHAQKNENAR 1780
Query: 201 KALTERQRDLEMKTQ----------------------QLEIKLSNKTEE---DIKKARRK 235
+ L + ++L++K Q QLE +L N+T+E K+ RR
Sbjct: 1781 QQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRT 1840
Query: 236 STQAGDDLMRCVD-LYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETD 294
+ D L++ D N Q K + +T L+ + ++E E Q + R +
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ---RANASRRKLQ 1897
Query: 295 MFNQSTVEPVDQLLRKVDPAKDR 317
+ E D + R+V K++
Sbjct: 1898 RELEDATETADAMNREVSSLKNK 1920
Score = 38.9 bits (89), Expect = 0.007
Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 37/214 (17%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSL-ASQEEGSLGEAWAQVKKSLADEAE 147
K + M ++ E +R K ++ K KL +S S + L A++K LA + E
Sbjct: 1024 KHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEE 1083
Query: 148 VHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKA----- 202
A++ E + M K +++ + I++L++ L S AS KA K
Sbjct: 1084 ELQAALARVEEEAAQKNMAL-----KKIRELESQISELQEDLESERASRNKAEKQKRDLG 1138
Query: 203 ---------------LTERQRDLEMKTQQLEIKLSNKT--------EEDIKKARRKSTQA 239
T Q++L K +Q E+ + KT E I++ R+K +QA
Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQ-EVNILKKTLEEEAKTHEAQIQEMRQKHSQA 1197
Query: 240 GDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEV 273
++L ++ + ++ E TLE ER E+
Sbjct: 1198 VEELAEQLEQTKRVKANL--EKAKQTLENERGEL 1229
Score = 37.0 bits (84), Expect = 0.025
Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 22/159 (13%)
Query: 123 LASQEEGSLGEAWAQVK---KSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
++ QEE + + VK K LA AE L L S++ + +E + + + C
Sbjct: 840 VSRQEEEMMAKEEELVKVREKQLA--AENRLTEMETLQSQLMAEKLQLQEQLQAETELC- 896
Query: 180 HHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTE--EDIKKARRKST 237
A E+ R LT ++++LE LE ++ + E + ++ ++K
Sbjct: 897 --------------AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 238 QAGDDLMRCVDLYNQAQSKWFEEMVTTTLELERLEVERV 276
Q +L ++ A+ K E VTT +L++LE E++
Sbjct: 943 QNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQI 981
Score = 30.0 bits (66), Expect = 3.0
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 106 KIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLM 165
K ++ + + LA+ S EE EA A+ K++ A L+ + + +E+E+
Sbjct: 1441 KKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNK 1500
Query: 166 NFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKT 225
FR + M D D+ K + +EK+++AL Q+ EMKTQ E++ +
Sbjct: 1501 QFRTEMEDLMSSKD----DVGKSVHE----LEKSKRAL--EQQVEEMKTQLEELEDELQA 1550
Query: 226 EEDIKKARRKSTQA 239
ED K + QA
Sbjct: 1551 TEDAKLRLEVNLQA 1564
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 48.5 bits (114), Expect = 8e-06
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 24/221 (10%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEV 148
K K + M + R+K EE + L KL + EG + Q+ A AE+
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL-----EGDASDFHEQIADLQAQIAEL 1081
Query: 149 HLKFSAKLHSEVEKPLMNF------RENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
++ AK E++ L + N K +++ + HI+DL++ L S A+ KA K
Sbjct: 1082 KMQL-AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 203 LTERQRDLEMKTQQLEIKL-SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEM 261
+ +LE +LE L S T+++++ R + L + +D ++ +EM
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM 1197
Query: 262 VTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVE 302
+ + VE + + L Q+ + + D N+ T+E
Sbjct: 1198 -------RQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLE 1230
Score = 40.0 bits (92), Expect = 0.003
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Query: 91 KQMQKEMSEFIRERIKIEEDYAKNLA----KLSQNSLASQEEGSLGEAWAQVKKSLADEA 146
KQ +E+ + R++ EED + L K++Q L +E+ EA Q + A
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 976
Query: 147 EVHLKFSAKLHSEVEKPLMNFREN-FKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 205
E +K KL E+ +M+ + N K+ K + I+DL LA E+ K LT+
Sbjct: 977 EAKIK---KLEDEIL--VMDDQNNKLSKERKLLEERISDLTTNLAEE----EEKAKNLTK 1027
Query: 206 RQRDLEMKTQQLEIKL--SNKTEEDIKKARRK 235
+ E +LE++L K+ ++++K +RK
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Score = 38.1 bits (87), Expect = 0.011
Identities = 42/203 (20%), Positives = 85/203 (41%), Gaps = 21/203 (10%)
Query: 126 QEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADL 185
+EE E Q K +AE LK + HS++ + +E + + +
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL-------- 902
Query: 186 RKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTE--EDIKKARRKSTQAGDDL 243
YA E+ R L ++++LE ++E +L + + + ++ R+K Q DL
Sbjct: 903 -------YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 244 MRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEP 303
++ A+ K E VT ++++LE E + M Q+ +L E + + +
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN----NKLSKERKLLEERISDL 1011
Query: 304 VDQLLRKVDPAKDRELWVREHKT 326
L + + AK+ +H++
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHES 1034
Score = 32.7 bits (73), Expect = 0.47
Identities = 36/182 (19%), Positives = 75/182 (41%), Gaps = 23/182 (12%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA-------- 136
Q L+ +++ +E++ + R ++++ + A+++Q +EE EA +
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 137 ---QVKKSLADEAEVHLKFSA----------KLHSEVEKPLMNFRENFKKDMKKCDHHIA 183
Q+ LA E K + +L S++ + + FK + + IA
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 184 DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDL 243
L +Q+ + A K+L +Q+D ++K L+++ K E K+ K L
Sbjct: 1825 QLEEQVEQEAREKQAATKSL--KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 244 MR 245
R
Sbjct: 1883 KR 1884
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 48.5 bits (114), Expect = 8e-06
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 24/221 (10%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEV 148
K K + M + R+K EE + L KL + EG + Q+ A AE+
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL-----EGDASDFHEQIADLQAQIAEL 1088
Query: 149 HLKFSAKLHSEVEKPLMNF------RENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
++ AK E++ L + N K +++ + HI+DL++ L S A+ KA K
Sbjct: 1089 KMQL-AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1147
Query: 203 LTERQRDLEMKTQQLEIKL-SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEM 261
+ +LE +LE L S T+++++ R + L + +D ++ +EM
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM 1204
Query: 262 VTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVE 302
+ + VE + + L Q+ + + D N+ T+E
Sbjct: 1205 -------RQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLE 1237
Score = 40.0 bits (92), Expect = 0.003
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Query: 91 KQMQKEMSEFIRERIKIEEDYAKNLA----KLSQNSLASQEEGSLGEAWAQVKKSLADEA 146
KQ +E+ + R++ EED + L K++Q L +E+ EA Q + A
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 147 EVHLKFSAKLHSEVEKPLMNFREN-FKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 205
E +K KL E+ +M+ + N K+ K + I+DL LA E+ K LT+
Sbjct: 984 EAKIK---KLEDEIL--VMDDQNNKLSKERKLLEERISDLTTNLAEE----EEKAKNLTK 1034
Query: 206 RQRDLEMKTQQLEIKL--SNKTEEDIKKARRK 235
+ E +LE++L K+ ++++K +RK
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRK 1066
Score = 38.1 bits (87), Expect = 0.011
Identities = 42/203 (20%), Positives = 85/203 (41%), Gaps = 21/203 (10%)
Query: 126 QEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADL 185
+EE E Q K +AE LK + HS++ + +E + + +
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL-------- 909
Query: 186 RKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTE--EDIKKARRKSTQAGDDL 243
YA E+ R L ++++LE ++E +L + + + ++ R+K Q DL
Sbjct: 910 -------YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 962
Query: 244 MRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEP 303
++ A+ K E VT ++++LE E + M Q+ +L E + + +
Sbjct: 963 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN----NKLSKERKLLEERISDL 1018
Query: 304 VDQLLRKVDPAKDRELWVREHKT 326
L + + AK+ +H++
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHES 1041
Score = 32.7 bits (73), Expect = 0.47
Identities = 36/182 (19%), Positives = 75/182 (41%), Gaps = 23/182 (12%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA-------- 136
Q L+ +++ +E++ + R ++++ + A+++Q +EE EA +
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771
Query: 137 ---QVKKSLADEAEVHLKFSA----------KLHSEVEKPLMNFRENFKKDMKKCDHHIA 183
Q+ LA E K + +L S++ + + FK + + IA
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831
Query: 184 DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDL 243
L +Q+ + A K+L +Q+D ++K L+++ K E K+ K L
Sbjct: 1832 QLEEQVEQEAREKQAATKSL--KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 244 MR 245
R
Sbjct: 1890 KR 1891
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 48.5 bits (114), Expect = 8e-06
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 24/221 (10%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEV 148
K K + M + R+K EE + L KL + EG + Q+ A AE+
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL-----EGDASDFHEQIADLQAQIAEL 1088
Query: 149 HLKFSAKLHSEVEKPLMNF------RENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
++ AK E++ L + N K +++ + HI+DL++ L S A+ KA K
Sbjct: 1089 KMQL-AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1147
Query: 203 LTERQRDLEMKTQQLEIKL-SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEM 261
+ +LE +LE L S T+++++ R + L + +D ++ +EM
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM 1204
Query: 262 VTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVE 302
+ + VE + + L Q+ + + D N+ T+E
Sbjct: 1205 -------RQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLE 1237
Score = 40.0 bits (92), Expect = 0.003
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Query: 91 KQMQKEMSEFIRERIKIEEDYAKNLA----KLSQNSLASQEEGSLGEAWAQVKKSLADEA 146
KQ +E+ + R++ EED + L K++Q L +E+ EA Q + A
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 983
Query: 147 EVHLKFSAKLHSEVEKPLMNFREN-FKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 205
E +K KL E+ +M+ + N K+ K + I+DL LA E+ K LT+
Sbjct: 984 EAKIK---KLEDEIL--VMDDQNNKLSKERKLLEERISDLTTNLAEE----EEKAKNLTK 1034
Query: 206 RQRDLEMKTQQLEIKL--SNKTEEDIKKARRK 235
+ E +LE++L K+ ++++K +RK
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQELEKLKRK 1066
Score = 38.1 bits (87), Expect = 0.011
Identities = 42/203 (20%), Positives = 85/203 (41%), Gaps = 21/203 (10%)
Query: 126 QEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADL 185
+EE E Q K +AE LK + HS++ + +E + + +
Sbjct: 858 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL-------- 909
Query: 186 RKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTE--EDIKKARRKSTQAGDDL 243
YA E+ R L ++++LE ++E +L + + + ++ R+K Q DL
Sbjct: 910 -------YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 962
Query: 244 MRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEP 303
++ A+ K E VT ++++LE E + M Q+ +L E + + +
Sbjct: 963 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN----NKLSKERKLLEERISDL 1018
Query: 304 VDQLLRKVDPAKDRELWVREHKT 326
L + + AK+ +H++
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHES 1041
Score = 32.7 bits (73), Expect = 0.47
Identities = 36/182 (19%), Positives = 75/182 (41%), Gaps = 23/182 (12%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA-------- 136
Q L+ +++ +E++ + R ++++ + A+++Q +EE EA +
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771
Query: 137 ---QVKKSLADEAEVHLKFSA----------KLHSEVEKPLMNFRENFKKDMKKCDHHIA 183
Q+ LA E K + +L S++ + + FK + + IA
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831
Query: 184 DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDL 243
L +Q+ + A K+L +Q+D ++K L+++ K E K+ K L
Sbjct: 1832 QLEEQVEQEAREKQAATKSL--KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1889
Query: 244 MR 245
R
Sbjct: 1890 KR 1891
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 48.5 bits (114), Expect = 8e-06
Identities = 52/221 (23%), Positives = 96/221 (43%), Gaps = 24/221 (10%)
Query: 89 KGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLADEAEV 148
K K + M + R+K EE + L KL + EG + Q+ A AE+
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKL-----EGDASDFHEQIADLQAQIAEL 1081
Query: 149 HLKFSAKLHSEVEKPLMNF------RENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
++ AK E++ L + N K +++ + HI+DL++ L S A+ KA K
Sbjct: 1082 KMQL-AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 203 LTERQRDLEMKTQQLEIKL-SNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEM 261
+ +LE +LE L S T+++++ R + L + +D ++ +EM
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTV---LKKALDEETRSHEAQVQEM 1197
Query: 262 VTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVE 302
+ + VE + + L Q+ + + D N+ T+E
Sbjct: 1198 -------RQKHAQAVEELTEQLEQFKRAKANLDK-NKQTLE 1230
Score = 40.0 bits (92), Expect = 0.003
Identities = 42/152 (27%), Positives = 73/152 (48%), Gaps = 16/152 (10%)
Query: 91 KQMQKEMSEFIRERIKIEEDYAKNLA----KLSQNSLASQEEGSLGEAWAQVKKSLADEA 146
KQ +E+ + R++ EED + L K++Q L +E+ EA Q + A
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTA 976
Query: 147 EVHLKFSAKLHSEVEKPLMNFREN-FKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 205
E +K KL E+ +M+ + N K+ K + I+DL LA E+ K LT+
Sbjct: 977 EAKIK---KLEDEIL--VMDDQNNKLSKERKLLEERISDLTTNLAEE----EEKAKNLTK 1027
Query: 206 RQRDLEMKTQQLEIKL--SNKTEEDIKKARRK 235
+ E +LE++L K+ ++++K +RK
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQELEKLKRK 1059
Score = 38.1 bits (87), Expect = 0.011
Identities = 42/203 (20%), Positives = 85/203 (41%), Gaps = 21/203 (10%)
Query: 126 QEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADL 185
+EE E Q K +AE LK + HS++ + +E + + +
Sbjct: 851 EEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETEL-------- 902
Query: 186 RKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTE--EDIKKARRKSTQAGDDL 243
YA E+ R L ++++LE ++E +L + + + ++ R+K Q DL
Sbjct: 903 -------YAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDL 955
Query: 244 MRCVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEP 303
++ A+ K E VT ++++LE E + M Q+ +L E + + +
Sbjct: 956 EEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQN----NKLSKERKLLEERISDL 1011
Query: 304 VDQLLRKVDPAKDRELWVREHKT 326
L + + AK+ +H++
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHES 1034
Score = 32.7 bits (73), Expect = 0.47
Identities = 36/182 (19%), Positives = 75/182 (41%), Gaps = 23/182 (12%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWA-------- 136
Q L+ +++ +E++ + R ++++ + A+++Q +EE EA +
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 137 ---QVKKSLADEAEVHLKFSA----------KLHSEVEKPLMNFRENFKKDMKKCDHHIA 183
Q+ LA E K + +L S++ + + FK + + IA
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 184 DLRKQLASRYASVEKARKALTERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDL 243
L +Q+ + A K+L +Q+D ++K L+++ K E K+ K L
Sbjct: 1825 QLEEQVEQEAREKQAATKSL--KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 1882
Query: 244 MR 245
R
Sbjct: 1883 KR 1884
>gi|16418431 nitric oxide synthase trafficker isoform 1 [Homo
sapiens]
Length = 428
Score = 47.8 bits (112), Expect = 1e-05
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 13/188 (6%)
Query: 146 AEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 205
A++H K + E KP +K K D+ + + S + KA+K L
Sbjct: 5 ADLHQKLGKAIELEAIKPTYQVLNVQEKKRKSLDNEVEKTANLVISNWNQQIKAKKKLMV 64
Query: 206 RQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQ-------AQSKWF 258
+ E Q +E + TE++ +K K T++ + L + + Y Q + KW
Sbjct: 65 STKKHEALFQLVESSKQSMTEKEKRKLLNKLTKSTEKLEKEDENYYQKNMAGYSTRLKWE 124
Query: 259 EEMVTTTLELERLEVERVEMIRQHLCQYTQLRHETDMFNQSTVEPVDQL---LRKVDPAK 315
+ + LE ER++++ +L QY+Q +F Q+ Q+ + K+D K
Sbjct: 125 NTLENCYQSILELEKERIQLLCNNLNQYSQ---HISLFGQTLTTCHTQIHCAISKIDIEK 181
Query: 316 DRELWVRE 323
D + + E
Sbjct: 182 DIQAVMEE 189
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 47.0 bits (110), Expect = 2e-05
Identities = 56/256 (21%), Positives = 109/256 (42%), Gaps = 44/256 (17%)
Query: 83 LLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSL 142
L ++ K KQ+ +E + R+ + A L +L++ LA Q +L E + K
Sbjct: 2266 LQEEAEKMKQVAEEAA-----RLSVAAQEAARLRQLAEEDLAQQR--ALAEKMLKEKMQA 2318
Query: 143 ADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
EA LK A+L L +E ++ ++ + +QLA ++ +A
Sbjct: 2319 VQEA-TRLKAEAEL-------LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 203 LTERQRDLEMKTQQLEIKLSN------KTEEDIKKARRKSTQAGDDLMR----------- 245
+RQ ++ + ++L+++++ + EED ++ R+++ + G+ L R
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2430
Query: 246 --CVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHL---------CQYTQLRHETD 294
+++ Q E + ELER E E+++ + L Q QL ET
Sbjct: 2431 VQTLEIQRQQSDHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2489
Query: 295 MFNQSTVEPVDQLLRK 310
QS + D LL++
Sbjct: 2490 ALQQSFLSEKDSLLQR 2505
Score = 35.4 bits (80), Expect = 0.073
Identities = 35/124 (28%), Positives = 62/124 (50%), Gaps = 6/124 (4%)
Query: 120 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
Q LA++EE EA +V+KSLA E E + A L EVE+ L E ++ ++ +
Sbjct: 1972 QRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL-EEVER-LKAKVEEARRLRERAE 2029
Query: 180 HHIA---DLRKQLASRYASVEKARKALTERQRDLEM-KTQQLEIKLSNKTEEDIKKARRK 235
A L ++ A + E+ A +Q++ E+ +T Q E + ++ + + ARR
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2089
Query: 236 STQA 239
+ +A
Sbjct: 2090 AEEA 2093
Score = 30.4 bits (67), Expect = 2.3
Identities = 40/198 (20%), Positives = 82/198 (41%), Gaps = 32/198 (16%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLAD 144
Q +++++ ++E RE+ K++++ AK L S+ Q+E L E A + L+
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQE-AKLLQLKSEEMQTVQQEQLLQETQALQQSFLS- 2497
Query: 145 EAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALT 204
EK + RE F + K A L + A ++ R+
Sbjct: 2498 ----------------EKDSLLQRERFIEQEK------AKLEQLFQDEVAKAQQLREEQQ 2535
Query: 205 ERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTT 264
+Q+ +E + Q+L + ++ARR+ +A + + R + Q + + ++
Sbjct: 2536 RQQQQMEQERQRLVASM--------EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2587
Query: 265 TLELERLEVERVEMIRQH 282
E +RL + + QH
Sbjct: 2588 AEENQRLREQLQLLEEQH 2605
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 47.0 bits (110), Expect = 2e-05
Identities = 56/256 (21%), Positives = 109/256 (42%), Gaps = 44/256 (17%)
Query: 83 LLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSL 142
L ++ K KQ+ +E + R+ + A L +L++ LA Q +L E + K
Sbjct: 2270 LQEEAEKMKQVAEEAA-----RLSVAAQEAARLRQLAEEDLAQQR--ALAEKMLKEKMQA 2322
Query: 143 ADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
EA LK A+L L +E ++ ++ + +QLA ++ +A
Sbjct: 2323 VQEA-TRLKAEAEL-------LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2374
Query: 203 LTERQRDLEMKTQQLEIKLSN------KTEEDIKKARRKSTQAGDDLMR----------- 245
+RQ ++ + ++L+++++ + EED ++ R+++ + G+ L R
Sbjct: 2375 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2434
Query: 246 --CVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHL---------CQYTQLRHETD 294
+++ Q E + ELER E E+++ + L Q QL ET
Sbjct: 2435 VQTLEIQRQQSDHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2493
Query: 295 MFNQSTVEPVDQLLRK 310
QS + D LL++
Sbjct: 2494 ALQQSFLSEKDSLLQR 2509
Score = 35.4 bits (80), Expect = 0.073
Identities = 35/124 (28%), Positives = 62/124 (50%), Gaps = 6/124 (4%)
Query: 120 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
Q LA++EE EA +V+KSLA E E + A L EVE+ L E ++ ++ +
Sbjct: 1976 QRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL-EEVER-LKAKVEEARRLRERAE 2033
Query: 180 HHIA---DLRKQLASRYASVEKARKALTERQRDLEM-KTQQLEIKLSNKTEEDIKKARRK 235
A L ++ A + E+ A +Q++ E+ +T Q E + ++ + + ARR
Sbjct: 2034 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2093
Query: 236 STQA 239
+ +A
Sbjct: 2094 AEEA 2097
Score = 30.4 bits (67), Expect = 2.3
Identities = 40/198 (20%), Positives = 82/198 (41%), Gaps = 32/198 (16%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLAD 144
Q +++++ ++E RE+ K++++ AK L S+ Q+E L E A + L+
Sbjct: 2444 QSDHDAERLREAIAELEREKEKLQQE-AKLLQLKSEEMQTVQQEQLLQETQALQQSFLS- 2501
Query: 145 EAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALT 204
EK + RE F + K A L + A ++ R+
Sbjct: 2502 ----------------EKDSLLQRERFIEQEK------AKLEQLFQDEVAKAQQLREEQQ 2539
Query: 205 ERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTT 264
+Q+ +E + Q+L + ++ARR+ +A + + R + Q + + ++
Sbjct: 2540 RQQQQMEQERQRLVASM--------EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2591
Query: 265 TLELERLEVERVEMIRQH 282
E +RL + + QH
Sbjct: 2592 AEENQRLREQLQLLEEQH 2609
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 47.0 bits (110), Expect = 2e-05
Identities = 56/256 (21%), Positives = 109/256 (42%), Gaps = 44/256 (17%)
Query: 83 LLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSL 142
L ++ K KQ+ +E + R+ + A L +L++ LA Q +L E + K
Sbjct: 2266 LQEEAEKMKQVAEEAA-----RLSVAAQEAARLRQLAEEDLAQQR--ALAEKMLKEKMQA 2318
Query: 143 ADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
EA LK A+L L +E ++ ++ + +QLA ++ +A
Sbjct: 2319 VQEA-TRLKAEAEL-------LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2370
Query: 203 LTERQRDLEMKTQQLEIKLSN------KTEEDIKKARRKSTQAGDDLMR----------- 245
+RQ ++ + ++L+++++ + EED ++ R+++ + G+ L R
Sbjct: 2371 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2430
Query: 246 --CVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHL---------CQYTQLRHETD 294
+++ Q E + ELER E E+++ + L Q QL ET
Sbjct: 2431 VQTLEIQRQQSDHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2489
Query: 295 MFNQSTVEPVDQLLRK 310
QS + D LL++
Sbjct: 2490 ALQQSFLSEKDSLLQR 2505
Score = 35.4 bits (80), Expect = 0.073
Identities = 35/124 (28%), Positives = 62/124 (50%), Gaps = 6/124 (4%)
Query: 120 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
Q LA++EE EA +V+KSLA E E + A L EVE+ L E ++ ++ +
Sbjct: 1972 QRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL-EEVER-LKAKVEEARRLRERAE 2029
Query: 180 HHIA---DLRKQLASRYASVEKARKALTERQRDLEM-KTQQLEIKLSNKTEEDIKKARRK 235
A L ++ A + E+ A +Q++ E+ +T Q E + ++ + + ARR
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2089
Query: 236 STQA 239
+ +A
Sbjct: 2090 AEEA 2093
Score = 30.4 bits (67), Expect = 2.3
Identities = 40/198 (20%), Positives = 82/198 (41%), Gaps = 32/198 (16%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLAD 144
Q +++++ ++E RE+ K++++ AK L S+ Q+E L E A + L+
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQE-AKLLQLKSEEMQTVQQEQLLQETQALQQSFLS- 2497
Query: 145 EAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALT 204
EK + RE F + K A L + A ++ R+
Sbjct: 2498 ----------------EKDSLLQRERFIEQEK------AKLEQLFQDEVAKAQQLREEQQ 2535
Query: 205 ERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTT 264
+Q+ +E + Q+L + ++ARR+ +A + + R + Q + + ++
Sbjct: 2536 RQQQQMEQERQRLVASM--------EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2587
Query: 265 TLELERLEVERVEMIRQH 282
E +RL + + QH
Sbjct: 2588 AEENQRLREQLQLLEEQH 2605
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 47.0 bits (110), Expect = 2e-05
Identities = 56/256 (21%), Positives = 109/256 (42%), Gaps = 44/256 (17%)
Query: 83 LLQKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSL 142
L ++ K KQ+ +E + R+ + A L +L++ LA Q +L E + K
Sbjct: 2234 LQEEAEKMKQVAEEAA-----RLSVAAQEAARLRQLAEEDLAQQR--ALAEKMLKEKMQA 2286
Query: 143 ADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKA 202
EA LK A+L L +E ++ ++ + +QLA ++ +A
Sbjct: 2287 VQEA-TRLKAEAEL-------LQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEA 2338
Query: 203 LTERQRDLEMKTQQLEIKLSN------KTEEDIKKARRKSTQAGDDLMR----------- 245
+RQ ++ + ++L+++++ + EED ++ R+++ + G+ L R
Sbjct: 2339 ERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTL 2398
Query: 246 --CVDLYNQAQSKWFEEMVTTTLELERLEVERVEMIRQHL---------CQYTQLRHETD 294
+++ Q E + ELER E E+++ + L Q QL ET
Sbjct: 2399 VQTLEIQRQQSDHDAERLREAIAELER-EKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQ 2457
Query: 295 MFNQSTVEPVDQLLRK 310
QS + D LL++
Sbjct: 2458 ALQQSFLSEKDSLLQR 2473
Score = 35.4 bits (80), Expect = 0.073
Identities = 35/124 (28%), Positives = 62/124 (50%), Gaps = 6/124 (4%)
Query: 120 QNSLASQEEGSLGEAWAQVKKSLADEAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCD 179
Q LA++EE EA +V+KSLA E E + A L EVE+ L E ++ ++ +
Sbjct: 1940 QRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL-EEVER-LKAKVEEARRLRERAE 1997
Query: 180 HHIA---DLRKQLASRYASVEKARKALTERQRDLEM-KTQQLEIKLSNKTEEDIKKARRK 235
A L ++ A + E+ A +Q++ E+ +T Q E + ++ + + ARR
Sbjct: 1998 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2057
Query: 236 STQA 239
+ +A
Sbjct: 2058 AEEA 2061
Score = 30.4 bits (67), Expect = 2.3
Identities = 40/198 (20%), Positives = 82/198 (41%), Gaps = 32/198 (16%)
Query: 85 QKQLKGKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEAWAQVKKSLAD 144
Q +++++ ++E RE+ K++++ AK L S+ Q+E L E A + L+
Sbjct: 2408 QSDHDAERLREAIAELEREKEKLQQE-AKLLQLKSEEMQTVQQEQLLQETQALQQSFLS- 2465
Query: 145 EAEVHLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALT 204
EK + RE F + K A L + A ++ R+
Sbjct: 2466 ----------------EKDSLLQRERFIEQEK------AKLEQLFQDEVAKAQQLREEQQ 2503
Query: 205 ERQRDLEMKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLYNQAQSKWFEEMVTT 264
+Q+ +E + Q+L + ++ARR+ +A + + R + Q + + ++
Sbjct: 2504 RQQQQMEQERQRLVASM--------EEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2555
Query: 265 TLELERLEVERVEMIRQH 282
E +RL + + QH
Sbjct: 2556 AEENQRLREQLQLLEEQH 2573
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,408,663
Number of Sequences: 37866
Number of extensions: 542471
Number of successful extensions: 2891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 402
Number of HSP's that attempted gapping in prelim test: 2349
Number of HSP's gapped (non-prelim): 890
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.