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Search of human proteins with 41352721
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
(476 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 955 0.0
gi|222418631 solute carrier family 36, member 2 [Homo sapiens] 664 0.0
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ... 570 e-163
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ... 550 e-157
gi|40807351 solute carrier family 36 (proton/amino acid symporte... 481 e-136
gi|17999520 solute carrier family 32, member 1 [Homo sapiens] 78 2e-14
gi|122937281 solute carrier family 38, member 8 [Homo sapiens] 56 8e-08
gi|24429574 solute carrier family 38, member 6 [Homo sapiens] 54 3e-07
gi|8922692 solute carrier family 38, member 7 [Homo sapiens] 54 4e-07
gi|27735137 solute carrier family 38, member 11 [Homo sapiens] 53 7e-07
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ... 52 1e-06
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ... 52 1e-06
gi|117168277 amino acid transporter system A1 [Homo sapiens] 50 3e-06
gi|117168275 amino acid transporter system A1 [Homo sapiens] 50 3e-06
gi|219689132 solute carrier family 38, member 4 [Homo sapiens] 50 4e-06
gi|18482385 solute carrier family 38, member 4 [Homo sapiens] 50 4e-06
gi|5870893 solute carrier family 38, member 3 [Homo sapiens] 47 4e-05
gi|21361602 solute carrier family 38, member 2 [Homo sapiens] 47 5e-05
gi|222418629 solute carrier family 38, member 9 [Homo sapiens] 45 2e-04
gi|193788624 solute carrier family 38, member 5 [Homo sapiens] 36 0.067
gi|187423910 solute carrier family 7, member 9 [Homo sapiens] 33 0.57
gi|7657591 solute carrier family 7, member 9 [Homo sapiens] 33 0.57
gi|110224458 solute carrier family 12, member 6 isoform e [Homo ... 32 0.97
gi|110224456 solute carrier family 12, member 6 isoform d [Homo ... 32 0.97
gi|110224454 solute carrier family 12, member 6 isoform c [Homo ... 32 0.97
gi|110224452 solute carrier family 12, member 6 isoform c [Homo ... 32 0.97
gi|4826780 solute carrier family 12, member 6 isoform b [Homo sa... 32 0.97
gi|110224449 solute carrier family 12, member 6 isoform a [Homo ... 32 0.97
gi|115430259 solute carrier family 39 (zinc transporter), member... 32 1.3
gi|115430255 solute carrier family 39 (zinc transporter), member... 32 1.3
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 955 bits (2469), Expect = 0.0
Identities = 476/476 (100%), Positives = 476/476 (100%)
Query: 1 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 60
MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN
Sbjct: 1 MSTQRLRNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGN 60
Query: 61 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 120
IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV
Sbjct: 61 IGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTV 120
Query: 121 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 180
MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC
Sbjct: 121 MYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNC 180
Query: 181 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 240
HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV
Sbjct: 181 HNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIV 240
Query: 241 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 300
QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT
Sbjct: 241 QRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVT 300
Query: 301 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 360
ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP
Sbjct: 301 ILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP 360
Query: 361 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 420
FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE
Sbjct: 361 FFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLE 420
Query: 421 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 476
VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI
Sbjct: 421 VTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTCAFI 476
>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
Length = 483
Score = 664 bits (1712), Expect = 0.0
Identities = 335/459 (72%), Positives = 382/459 (83%), Gaps = 5/459 (1%)
Query: 19 VSPEESPSEGLNNLS-----SPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVK 73
+SP ES + N S SP ++ T FQ LIHL+KGN+GTG+LGLPLAVK
Sbjct: 21 MSPPESAKKLENKDSTFLDESPSESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVK 80
Query: 74 NAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLR 133
NAGI+MGP+SLL++G +A HCM ILVKCA FC+RLNK F+DYGDTVM+GLE++P +WL+
Sbjct: 81 NAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPFMDYGDTVMHGLEANPNAWLQ 140
Query: 134 NHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMD 193
NHAHWGR +V FFLI+TQLGFCCVY VFLADN KQV+EA N TTNNC++NETVILTPTMD
Sbjct: 141 NHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNETVILTPTMD 200
Query: 194 SRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVA 253
SRLYMLSFLPFLVLLV IRNLR L+IFS+LANI+MLVSLV+I Q+I Q IPDPS LPLVA
Sbjct: 201 SRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLVIIIQYITQEIPDPSRLPLVA 260
Query: 254 PWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQ 313
WKTYPLFFGTAIFSFE IG+VLPLENKMK+ R FP IL LGM IVT LYI + LGYL+
Sbjct: 261 SWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFPAILSLGMSIVTSLYIGMAALGYLR 320
Query: 314 FGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELV 373
FG +I+ SI+LNLPNCWLYQSVKLLY GI TYALQFYVPAEIIIPF +SR L
Sbjct: 321 FGDDIKASISLNLPNCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTRWALP 380
Query: 374 VDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLT 433
+DL +R V+VCLTC+LAILIPRLDLVISLVGSVS +ALALIIPPLLEVTTFYSEGMSPLT
Sbjct: 381 LDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYSEGMSPLT 440
Query: 434 IFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINST 472
IFKDALISILGFVGFVVGTY+AL EL++ ++ F NST
Sbjct: 441 IFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNST 479
>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
sapiens]
Length = 470
Score = 570 bits (1470), Expect = e-163
Identities = 288/458 (62%), Positives = 363/458 (79%), Gaps = 4/458 (0%)
Query: 6 LRNEDYH-DYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTG 64
L DY+ + +S D P+ SPSE ++++S + G++ + QTLIHLLK NIGTG
Sbjct: 3 LLGRDYNSELNSLDNGPQ-SPSESSSSITSENVHPA-GEAG-LSMMQTLIHLLKCNIGTG 59
Query: 65 LLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGL 124
LLGLPLA+KNAG+++GP+SLL IG++ VHCM IL+ CA H +RL K+FV+YG+ MYGL
Sbjct: 60 LLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGL 119
Query: 125 ESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNE 184
E+ P +WLR HA WGR V F L++TQLGFC VYF+F+ADN +Q++E A+ T+N C E
Sbjct: 120 ETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPRE 179
Query: 185 TVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIP 244
+ LTP +D R YML LPFL+LLVFI+NL+ LS+FS LANIT L S+ +I+++I++ IP
Sbjct: 180 ILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIP 239
Query: 245 DPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYI 304
PS+LPL+A WKT+ LFFGTAIF+FEG+GMVLPL+N+MK P++F +LYLGM IV ILYI
Sbjct: 240 YPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYI 299
Query: 305 SLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVS 364
LG LGY++FG++ Q SITLNLPNCWLYQSVKL+YSIGIFFTYALQF+VPAEIIIPF +S
Sbjct: 300 LLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAIS 359
Query: 365 RAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTF 424
+ E L VDL VR+ LVCLTC+ AILIPRLDLVISLVGSVSSSALALIIP LLE+ F
Sbjct: 360 QVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIF 419
Query: 425 YSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQP 462
YSE MS +TI KD +ISI+G +G + GTY+ALYEL QP
Sbjct: 420 YSEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQP 457
>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
sapiens]
Length = 511
Score = 550 bits (1418), Expect = e-157
Identities = 288/499 (57%), Positives = 363/499 (72%), Gaps = 45/499 (9%)
Query: 6 LRNEDYH-DYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTG 64
L DY+ + +S D P+ SPSE ++++S + G++ + QTLIHLLK NIGTG
Sbjct: 3 LLGRDYNSELNSLDNGPQ-SPSESSSSITSENVHPA-GEAG-LSMMQTLIHLLKCNIGTG 59
Query: 65 LLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGL 124
LLGLPLA+KNAG+++GP+SLL IG++ VHCM IL+ CA H +RL K+FV+YG+ MYGL
Sbjct: 60 LLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGL 119
Query: 125 ESSPCSWLRNHAHWGR-----------------------------------------RVV 143
E+ P +WLR HA WGR V
Sbjct: 120 ETCPNTWLRAHAVWGRWNLALSPRLECSGKISAHCNPHLQGSSNSPAQASRVAGIYRYTV 179
Query: 144 DFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLP 203
F L++TQLGFC VYF+F+ADN +Q++E A+ T+N C E + LTP +D R YML LP
Sbjct: 180 SFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILP 239
Query: 204 FLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFG 263
FL+LLVFI+NL+ LS+FS LANIT L S+ +I+++I++ IP PS+LPL+A WKT+ LFFG
Sbjct: 240 FLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFG 299
Query: 264 TAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSIT 323
TAIF+FEG+GMVLPL+N+MK P++F +LYLGM IV ILYI LG LGY++FG++ Q SIT
Sbjct: 300 TAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASIT 359
Query: 324 LNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLV 383
LNLPNCWLYQSVKL+YSIGIFFTYALQF+VPAEIIIPF +S+ E L VDL VR+ LV
Sbjct: 360 LNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALV 419
Query: 384 CLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISIL 443
CLTC+ AILIPRLDLVISLVGSVSSSALALIIP LLE+ FYSE MS +TI KD +ISI+
Sbjct: 420 CLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIV 479
Query: 444 GFVGFVVGTYEALYELIQP 462
G +G + GTY+ALYEL QP
Sbjct: 480 GLLGCIFGTYQALYELPQP 498
>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
member 4 [Homo sapiens]
Length = 504
Score = 481 bits (1239), Expect = e-136
Identities = 247/439 (56%), Positives = 322/439 (73%), Gaps = 13/439 (2%)
Query: 48 TWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCR 107
++ QTL+HLLKGNIGTGLLGLPLA+KNAGIV+GPISL+ IGI++VHCM ILV+C+H C
Sbjct: 60 SFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCL 119
Query: 108 RLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFK 167
R KS + Y DTV + +E SP S L+ A WGR VVDFFL++TQLGFC VY VFLA+N K
Sbjct: 120 RFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVK 179
Query: 168 QVIEA---ANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLA 224
QV E + +N N+ ++D R+YML FLPF++LLVFIR L+ L + S LA
Sbjct: 180 QVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLA 239
Query: 225 NITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKD 284
N++M VSLV+IYQ++V+ +PDP +LP+VA WK YPLFFGTA+F+FEGIG+VLPLEN+MK+
Sbjct: 240 NVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKE 299
Query: 285 PRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGI 343
++FP L +GM IVT LY++L LGY+ F I+GSITLNLP + WLYQSVK+LYS GI
Sbjct: 300 SKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGI 359
Query: 344 FFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLV 403
F TY++QFYVPAEIIIP S+ + + + +R+ LV +TC AILIPRLD+VIS V
Sbjct: 360 FVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFV 419
Query: 404 GSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPS 463
G+VSSS LALI+PPL+E+ TF E + + K+ I+ G VGF++GTY + E+I P+
Sbjct: 420 GAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPT 479
Query: 464 --------NAPIF-INSTC 473
+P +NSTC
Sbjct: 480 PKVVAGTPQSPFLNLNSTC 498
>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
Length = 525
Score = 77.8 bits (190), Expect = 2e-14
Identities = 97/451 (21%), Positives = 186/451 (41%), Gaps = 42/451 (9%)
Query: 25 PSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISL 84
PS + + G + + T W + ++ G +LGLP A+ + G +G +
Sbjct: 95 PSGSKDQVGGGGEFGGHDKPKITAW-EAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLI 152
Query: 85 LIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVD 144
+ +V + IL+ C + + V D+ + + ++ C+ G RVV+
Sbjct: 153 IFAAVVCCYTGKILIACLYE--ENEDGEVVRVRDSYV-AIANACCA--PRFPTLGGRVVN 207
Query: 145 FFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPF 204
I+ +L C+ +V ++ N +N+ P + S +
Sbjct: 208 VAQII-ELVMTCILYVVVSGNLM-------------YNS-----FPGLPVSQKSWSIIAT 248
Query: 205 LVLL--VFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPS--HLPLVAPWKTYPL 260
VLL F++NL+A+S FSLL + V +++ + + R D + + K +P+
Sbjct: 249 AVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPI 308
Query: 261 FFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQG 320
G +FS+ + LE M+ P +F ++ + +L + YL + +
Sbjct: 309 SIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKE 368
Query: 321 SITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP---------FFVSRAPEHCE 371
IT NLP + V + +Y L F+ E++ FF +
Sbjct: 369 VITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGR 427
Query: 372 LVV-DLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMS 430
L L +R LV T ++AI +P L++ L GS++ + L ++P L + + + +
Sbjct: 428 LKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRK-LL 486
Query: 431 PLTIFKDALISILGFVGFVVGTYEALYELIQ 461
+F D I ++G + V G +L LI+
Sbjct: 487 WHQVFFDVAIFVIGGICSVSGFVHSLEGLIE 517
>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
Length = 435
Score = 55.8 bits (133), Expect = 8e-08
Identities = 79/416 (18%), Positives = 162/416 (38%), Gaps = 45/416 (10%)
Query: 56 LLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVD 115
L+K +G GLL P A AG V+ + ++ +V + G+++ L +
Sbjct: 33 LMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFL-ISGLVI---------LGYAAAV 82
Query: 116 YGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANG 175
G G+ C ++ + ++ L + + D +++ ++
Sbjct: 83 SGQATYQGVVRGLCGPAIG------KLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLS 136
Query: 176 TTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVF-----IRNLRALSIFSLLANITMLV 230
T P + + L L LV+L I + SI LA + +
Sbjct: 137 GTPPAPQ-------PWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLAL 189
Query: 231 SLVMIYQFIVQRIPDPSHLPLV-APWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPR--K 287
+ + Y Q + SH L A W + F T F F+ + + M+
Sbjct: 190 VITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSH 249
Query: 288 FPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFT 346
+ L+ L ++ ++Y G G+L FG + + ++ P N + ++L+++ I
Sbjct: 250 WALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTV 309
Query: 347 YALQFYVPAEIIIPFF---------VSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLD 397
Y + ++ ++ F+ S + L V + + + V +T +A+ +P L
Sbjct: 310 YPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLS 369
Query: 398 LVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTY 453
++S++G +SS + I P L + G+ P+ + + G V +VGT+
Sbjct: 370 EIVSIIGGISSFFI-FIFPGLCLICAM---GVEPIGPRVKCCLEVWGVVSVLVGTF 421
>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
Length = 456
Score = 53.9 bits (128), Expect = 3e-07
Identities = 87/450 (19%), Positives = 181/450 (40%), Gaps = 43/450 (9%)
Query: 21 PEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMG 80
PEE+ +E L+ L S +++ +S ++ ++ +L+ +G+G+LGL + N G+
Sbjct: 21 PEEAEAEELSPLLSNELHRQ--RSPGVSFGLSVFNLMNAIMGSGILGLAYVMANTGVFGF 78
Query: 81 PISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGR 140
LL + ++A + + +L+ + + Y D ++ G+
Sbjct: 79 SFLLLTVALLASYSVHLLLSMC------IQTAVTSYEDLGLFAFGLP-----------GK 121
Query: 141 RVVDFFLIVTQLGFCCVYFVFLADNFKQVI-EAANGTTNNCH--NNETVILTPTMDSRLY 197
VV +I+ +G Y + + I E G + + +T+++ + ++
Sbjct: 122 LVVAGTIIIQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGI-VF 180
Query: 198 MLSFLPFLVLLVFIRNLRA--LSIFSLLANI---TMLVSLVMIYQ---FIVQRIPDPSHL 249
L+ LP + L + +L + F+L+ I ++ L + Y F + + D
Sbjct: 181 PLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGFQISNVTDDCKP 240
Query: 250 PLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPL--ILYLGMVIVTILYISLG 307
L K T FSF +LP+ +++ P K + + + + ++Y
Sbjct: 241 KLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKKRMQNVTNTAIALSFLIYFISA 300
Query: 308 CLGYLQFGANIQGSITLN----LPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV 363
GYL F ++ + L + + +VKL + T L + + + F
Sbjct: 301 LFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFF 360
Query: 364 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTT 423
S P + + L + +LAI +P + V +VG+ +S+ L I P L +
Sbjct: 361 SNFP--FSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKL 418
Query: 424 FYSEGMSPLTIFKDALISILGFVGFVVGTY 453
+ +S +K +L G +VG +
Sbjct: 419 SREDFLS----WKKLGAFVLLIFGILVGNF 444
>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
Length = 462
Score = 53.5 bits (127), Expect = 4e-07
Identities = 86/415 (20%), Positives = 160/415 (38%), Gaps = 54/415 (13%)
Query: 33 SSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAV 92
+SPG R +T+ + ++ +G GLL P A AG V I+L + G++
Sbjct: 41 ASPGGLDR----GTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQM-GMLVF 95
Query: 93 HCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQL 152
G+++ +C + + Y + V + C L + + + V
Sbjct: 96 IISGLVILA---YCSQASNERT-YQEVVW-----AVCGKLTGV------LCEVAIAVYTF 140
Query: 153 GFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFI- 211
G C + + + D ++I P R + +S FL +L
Sbjct: 141 GTCIAFLIIIGDQQDKIIAVMAKEPEGASG-------PWYTDRKFTISLTAFLFILPLSI 193
Query: 212 -RNLRALSIFSLLANI-TMLVSLVMIYQFIVQRIPDPSHLP-----LVAPWKTYPLFFGT 264
R + S L+ + T V+ ++I ++I PD P A W T
Sbjct: 194 PREIGFQKYASFLSVVGTWYVTAIVIIKYIW---PDKEMTPGNILTRPASWMAVFNAMPT 250
Query: 265 AIFSFEGIGMVLPLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSI 322
F F+ +P+ N M+ P + + ++ MVI +Y+ G G+L FGA + +
Sbjct: 251 ICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDV 310
Query: 323 TLNLPNCWLYQSVKLLYSI-GIFFTYALQFYVPAEII---------IPFFVSRAPEHCEL 372
L+ P+ + +V + I + +Y + + ++ +P E
Sbjct: 311 LLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRR 370
Query: 373 VVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSE 427
V+ V LT +LA+ IP + VIS++G + ++ + P L + SE
Sbjct: 371 VLQTL---VWFLLTLLLALFIPDIGKVISVIGGL-AACFIFVFPGLCLIQAKLSE 421
>gi|27735137 solute carrier family 38, member 11 [Homo sapiens]
Length = 384
Score = 52.8 bits (125), Expect = 7e-07
Identities = 60/280 (21%), Positives = 121/280 (43%), Gaps = 34/280 (12%)
Query: 199 LSFLPFLVLLVFIRNLRALSIFSLLAN--ITMLVSLVMIYQFIVQRIPDPSHLPLVAPWK 256
LS + F + L RN+ L SL++ T+++ +VM + I H+P K
Sbjct: 81 LSTVTFTLPLSLYRNIAKLGKVSLISTGLTTLILGIVM-----ARAISLGPHIP-----K 130
Query: 257 TYPLFFGTAIFSFEGIGMV----------LPLENKMKDPR--KFPLILYLGMVIVTILYI 304
T + + + +G++ + + +++P K+ ++++ +VI + I
Sbjct: 131 TEDAWVFAKPNAIQAVGVMSFAFICHHNSFLVYSSLEEPTVAKWSRLIHMSIVISVFICI 190
Query: 305 SLGCLGYLQFGANIQGSITLN-LPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV 363
GYL F QG + N N L + Y + + TY ++ +V E+I F
Sbjct: 191 FFATCGYLTFTGFTQGDLFENYCRNDDLVTFGRFCYGVTVILTYPMECFVTREVIANVFF 250
Query: 364 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLL---- 419
+ V + V +++ + ++++LI L +V+ L G + ++ L IIP
Sbjct: 251 G---GNLSSVFHIVVTVMVITVATLVSLLIDCLGIVLELNGVLCATPLIFIIPSACYLKL 307
Query: 420 --EVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALY 457
E T + MS + + A++ + GFV + T + +
Sbjct: 308 SEEPRTHSDKIMSCVMLPIGAVVMVFGFVMAITNTQDCTH 347
>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
sapiens]
Length = 1119
Score = 52.0 bits (123), Expect = 1e-06
Identities = 73/393 (18%), Positives = 152/393 (38%), Gaps = 65/393 (16%)
Query: 53 LIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRL--N 110
+ +++ +G +L +P K GIV+G + L+ + LVK A RR
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71
Query: 111 KSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADN----F 166
+F YG G+ +V+ +I LG C ++V + D F
Sbjct: 72 LAFHAYGKA-------------------GKMLVETSMIGLMLGTCIAFYVVIGDLGSNFF 112
Query: 167 KQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFI--RNLRA-LSIFSLL 223
++ G T R+++L + ++L RN+ A + FS +
Sbjct: 113 ARLFGFQVGGT----------------FRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAM 156
Query: 224 ANITMLVSLVMIYQ-------FIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVL 276
A + V + +I F Q + S++ ++ P+F SF VL
Sbjct: 157 ALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFG----MSFACQSQVL 212
Query: 277 PLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQS 334
P + + +P + I + +VT Y+ +G GY+ F G++ ++ P+ + +
Sbjct: 213 PTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEM 272
Query: 335 VKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTV--------LVCLT 386
+++ + + + + + + + + + ++ + +V T
Sbjct: 273 LRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGT 332
Query: 387 CILAILIPRLDLVISLVGSVSSSALALIIPPLL 419
+ ILIP ++ ++ L G+ S + I P L+
Sbjct: 333 MVGGILIPNVETILGLTGATMGSLICFICPALI 365
>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
sapiens]
Length = 780
Score = 52.0 bits (123), Expect = 1e-06
Identities = 73/393 (18%), Positives = 152/393 (38%), Gaps = 65/393 (16%)
Query: 53 LIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRL--N 110
+ +++ +G +L +P K GIV+G + L+ + LVK A RR
Sbjct: 12 ITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAG 71
Query: 111 KSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADN----F 166
+F YG G+ +V+ +I LG C ++V + D F
Sbjct: 72 LAFHAYGKA-------------------GKMLVETSMIGLMLGTCIAFYVVIGDLGSNFF 112
Query: 167 KQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVLLVFI--RNLRA-LSIFSLL 223
++ G T R+++L + ++L RN+ A + FS +
Sbjct: 113 ARLFGFQVGGT----------------FRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAM 156
Query: 224 ANITMLVSLVMIYQ-------FIVQRIPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVL 276
A + V + +I F Q + S++ ++ P+F SF VL
Sbjct: 157 ALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFG----MSFACQSQVL 212
Query: 277 PLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQS 334
P + + +P + I + +VT Y+ +G GY+ F G++ ++ P+ + +
Sbjct: 213 PTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEM 272
Query: 335 VKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVRTV--------LVCLT 386
+++ + + + + + + + + + ++ + +V T
Sbjct: 273 LRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGT 332
Query: 387 CILAILIPRLDLVISLVGSVSSSALALIIPPLL 419
+ ILIP ++ ++ L G+ S + I P L+
Sbjct: 333 MVGGILIPNVETILGLTGATMGSLICFICPALI 365
>gi|117168277 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 50.4 bits (119), Expect = 3e-06
Identities = 84/439 (19%), Positives = 169/439 (38%), Gaps = 58/439 (13%)
Query: 46 STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHF 105
+T+ ++ +L +G+G+LGL A+ N GI++ + L + +++++ + +L+ C+
Sbjct: 70 TTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKET 129
Query: 106 -CRRLNKS----FVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFV 160
C K F G V++G S + G Y
Sbjct: 130 GCMVYEKLGEQVFGTTGKFVIFGATS----------------------LQNTGAMLSYLF 167
Query: 161 FLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVL-LVFIRNLRAL-- 217
+ + I+ G E +D R+ ++ ++L L ++NL L
Sbjct: 168 IVKNELPSAIKFLMG-------KEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGY 220
Query: 218 -SIFSLLANITMLVSLVMIYQFIVQRIPDPSHL------------PLVAPWKTYPLF-FG 263
S FSL + L+ ++ I +P+ + P + + ++
Sbjct: 221 TSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALP 280
Query: 264 TAIFSFEGIGMVLPLENKMKD--PRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGS 321
T F+F VLP+ +++KD +K ++ + + ++Y GYL F N+Q
Sbjct: 281 TIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSD 340
Query: 322 IT--LNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVR 379
+ + L +V+L + + T + F+ + C V V
Sbjct: 341 LLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTV---VT 397
Query: 380 TVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDAL 439
+L+ + +L I IP + + +VG S++ L I+P L + +G AL
Sbjct: 398 CILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAAL 457
Query: 440 ISILGFVGFVVGTYEALYE 458
LG + +V +Y+
Sbjct: 458 FLGLGVLFSLVSIPLVIYD 476
>gi|117168275 amino acid transporter system A1 [Homo sapiens]
Length = 487
Score = 50.4 bits (119), Expect = 3e-06
Identities = 84/439 (19%), Positives = 169/439 (38%), Gaps = 58/439 (13%)
Query: 46 STTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHF 105
+T+ ++ +L +G+G+LGL A+ N GI++ + L + +++++ + +L+ C+
Sbjct: 70 TTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKET 129
Query: 106 -CRRLNKS----FVDYGDTVMYGLESSPCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFV 160
C K F G V++G S + G Y
Sbjct: 130 GCMVYEKLGEQVFGTTGKFVIFGATS----------------------LQNTGAMLSYLF 167
Query: 161 FLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLVL-LVFIRNLRAL-- 217
+ + I+ G E +D R+ ++ ++L L ++NL L
Sbjct: 168 IVKNELPSAIKFLMG-------KEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGY 220
Query: 218 -SIFSLLANITMLVSLVMIYQFIVQRIPDPSHL------------PLVAPWKTYPLF-FG 263
S FSL + L+ ++ I +P+ + P + + ++
Sbjct: 221 TSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALP 280
Query: 264 TAIFSFEGIGMVLPLENKMKD--PRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGS 321
T F+F VLP+ +++KD +K ++ + + ++Y GYL F N+Q
Sbjct: 281 TIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSD 340
Query: 322 IT--LNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLFVR 379
+ + L +V+L + + T + F+ + C V V
Sbjct: 341 LLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTV---VT 397
Query: 380 TVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDAL 439
+L+ + +L I IP + + +VG S++ L I+P L + +G AL
Sbjct: 398 CILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAAL 457
Query: 440 ISILGFVGFVVGTYEALYE 458
LG + +V +Y+
Sbjct: 458 FLGLGVLFSLVSIPLVIYD 476
>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 50.1 bits (118), Expect = 4e-06
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 19/198 (9%)
Query: 266 IFSFEGIGMVLPLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSI- 322
+F+F VLP+ +++KD RK + + + + ++Y+ GYL F ++ +
Sbjct: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
Query: 323 -------TLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVD 375
TL++P V+L + + T + + +I + P +
Sbjct: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRP--FSWIRH 453
Query: 376 LFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGM-SPLTI 434
+ VL+ L +L IL+P + + +G+ S++ L I+P + + E SP +
Sbjct: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513
Query: 435 FKDALISILGFVGFVVGT 452
ALI ++ + F++G+
Sbjct: 514 --GALIFLVVGIFFMIGS 529
Score = 39.3 bits (90), Expect = 0.008
Identities = 21/89 (23%), Positives = 46/89 (51%)
Query: 14 YSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVK 73
+++ D ++ + G Y +T++ + +L +G+G+LGL A+
Sbjct: 42 FANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMA 101
Query: 74 NAGIVMGPISLLIIGIVAVHCMGILVKCA 102
N GI++ I LL + I++++ + +L+K A
Sbjct: 102 NTGIILFIIMLLAVAILSLYSVHLLLKTA 130
>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
Length = 547
Score = 50.1 bits (118), Expect = 4e-06
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 19/198 (9%)
Query: 266 IFSFEGIGMVLPLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSI- 322
+F+F VLP+ +++KD RK + + + + ++Y+ GYL F ++ +
Sbjct: 340 VFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELL 399
Query: 323 -------TLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVD 375
TL++P V+L + + T + + +I + P +
Sbjct: 400 HAYSKVYTLDIP----LLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRP--FSWIRH 453
Query: 376 LFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGM-SPLTI 434
+ VL+ L +L IL+P + + +G+ S++ L I+P + + E SP +
Sbjct: 454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKV 513
Query: 435 FKDALISILGFVGFVVGT 452
ALI ++ + F++G+
Sbjct: 514 --GALIFLVVGIFFMIGS 529
Score = 39.3 bits (90), Expect = 0.008
Identities = 21/89 (23%), Positives = 46/89 (51%)
Query: 14 YSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVK 73
+++ D ++ + G Y +T++ + +L +G+G+LGL A+
Sbjct: 42 FANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMA 101
Query: 74 NAGIVMGPISLLIIGIVAVHCMGILVKCA 102
N GI++ I LL + I++++ + +L+K A
Sbjct: 102 NTGIILFIIMLLAVAILSLYSVHLLLKTA 130
>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
Length = 504
Score = 47.0 bits (110), Expect = 4e-05
Identities = 101/478 (21%), Positives = 176/478 (36%), Gaps = 62/478 (12%)
Query: 21 PEESPSEGLNNLS-SPGSYQRFGQSNSTTWF-QTLIHLLKGNIGTGLLGLPLAVKNAGIV 78
P S EG + L SP F T F ++ +L +G+G+LGL A+ N GI+
Sbjct: 38 PARSCMEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGII 97
Query: 79 MGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHW 138
+ L + +++ + + +L+K + + G+ + R
Sbjct: 98 LFLFLLTAVALLSSYSIHLLLKSSG-----------------VVGIRAYEQLGYRAFGTP 140
Query: 139 GRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEA------------ANGTTNNCHNNETV 186
G+ + + +G Y + VI+ NG + T+
Sbjct: 141 GKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTI 200
Query: 187 ILTPTMDSRL--------YMLSFLPFLVLLVFIRNLRA-LSIFSLLANITMLVSLVMIYQ 237
IL + +L + LS + F ++ V + + N T S V I +
Sbjct: 201 ILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVK 260
Query: 238 FIVQRIPDPSHLPLVAPWKTYPLFFGTAI------FSFEGIGMVLPLENKMKDP--RKFP 289
VQ +P P + L TA F+F VLP+ ++KDP +K
Sbjct: 261 EKVQLQVEPEASAFCTP-SYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQ 319
Query: 290 LILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYAL 349
I L + ++ I+Y GYL F ++ + + + L + + A+
Sbjct: 320 HISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVL--TAV 377
Query: 350 QFYVPAEIIIPFFVSRAPEHCELVVDLF--VRTVLVC---LTCI--LAILIPRLDLVISL 402
VP I+ F V RA + F +R VL+ LTCI L I P + + +
Sbjct: 378 TLTVP---IVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGV 434
Query: 403 VGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELI 460
+G+ S+ L I P + +E P L +GF++ T + +I
Sbjct: 435 IGATSAPFLIFIFPAIFYFRIMPTE-KEPARSTPKILALCFAMLGFLLMTMSLSFIII 491
>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
Length = 506
Score = 46.6 bits (109), Expect = 5e-05
Identities = 100/492 (20%), Positives = 187/492 (38%), Gaps = 75/492 (15%)
Query: 18 DVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGI 77
DV PE +NL Y+ +T++ ++ +L +G+G+LGL A+ N GI
Sbjct: 43 DVDPENQNFLLESNLGKK-KYETEFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGI 101
Query: 78 VMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAH 137
+ I L + I +++ + +L+K A+ G +++Y L
Sbjct: 102 ALFIILLTFVSIFSLYSVHLLLKTANE------------GGSLLYEQLGYKAFGL----- 144
Query: 138 WGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLY 197
G+ + + +G Y + VI+A + L + L
Sbjct: 145 VGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNI------EDKTGLWYLNGNYLV 198
Query: 198 MLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLV----- 252
+L L ++ L RNL L S L+ + M+ L+++ Q +P P L+
Sbjct: 199 LLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQ-VPCPVEAALIINETI 257
Query: 253 ----------APWKTY---------PLFF----------GTAIFSFEGIGMVLPLENKMK 283
P ++ P +F IFSF VLP+ ++K
Sbjct: 258 NTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELK 317
Query: 284 D--PRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNCWLYQSVKLLYSI 341
D R+ + + + ++Y+ GYL F +++ + L+ + L + LL +
Sbjct: 318 DRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESEL-LHTYSSILGTDI-LLLIV 375
Query: 342 GIFFTYALQFYVPAEIIIPFFVSRAPEHCELVVDLF-------VRTVLVCLTCILAILIP 394
+ A+ VP ++ F + + H F + ++ T +L I +P
Sbjct: 376 RLAVLMAVTLTVP---VVIFPIRSSVTHLLCASKDFSWWRHSLITVSILAFTNLLVIFVP 432
Query: 395 RLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYE 454
+ + +G+ ++S L I+P + E M + AL +L V + G+
Sbjct: 433 TIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKI-GALFFLLSGVLVMTGSM- 490
Query: 455 ALYELIQPSNAP 466
AL L NAP
Sbjct: 491 ALIVLDWVHNAP 502
>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
Length = 561
Score = 44.7 bits (104), Expect = 2e-04
Identities = 87/459 (18%), Positives = 178/459 (38%), Gaps = 83/459 (18%)
Query: 52 TLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNK 111
T+ + +GT +L +P +K AG G ++++G++ ++C C R+ K
Sbjct: 122 TIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLYC-----------CYRVVK 170
Query: 112 SFVDYGDTVMYGLESSPCSWLRNHAHW----GRRVVDFFLIVTQLGFCCVYFVFLADNFK 167
S T+M+ L+++ + H+ G+ F +V+ +G VY+V +++
Sbjct: 171 S-----RTMMFSLDTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLF 225
Query: 168 QVIEAANGTTNNCHNNETVILT----------------PTMDSRLYMLS----------- 200
+ ++ ++ +T++ T P S ++ +
Sbjct: 226 NTGKFIFNFIHHINDTDTILSTNNSNPVICPSAGSGGHPDNSSMIFYANDTGAQQFEKWW 285
Query: 201 ----FLPFLV--LLVFIRNLRALSIFS---LLANITMLVSLVMIYQFIVQR--------- 242
+PF + LL+ + N ++ S FS +L +++L L+ + F R
Sbjct: 286 DKSRTVPFYLVGLLLPLLNFKSPSFFSKFNILGTVSVLY-LIFLVTFKAVRLGFHLEFHW 344
Query: 243 -IPDPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTI 301
IP +P + +P G +F ++ L K L + ++VT+
Sbjct: 345 FIPTEFFVPEIR--FQFPQLTGVLTLAFFIHNCIITLLKNNKKQENNVRDLCIAYMLVTL 402
Query: 302 LYISLGCLGYLQFGAN------IQGSITLNLPNCWLYQSVKLLYSIGIFFT-YALQFYVP 354
Y+ +G L + F + I+ + N P+ + ++ + T Y L Y+
Sbjct: 403 TYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFIARIFLLFQMMTVYPLLGYLA 462
Query: 355 -AEIIIPFFVSRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALAL 413
+++ F P + L + ++V I+A P + +I G+ A
Sbjct: 463 RVQLLGHIFGDIYPSIFHV---LILNLIIVGAGVIMACFYPNIGGIIRYSGAACGLAFVF 519
Query: 414 IIPPLLEVTTFYSEGMS--PLTIFKDALISILGFVGFVV 450
I P L+ + + + E P IF I ILG +V
Sbjct: 520 IYPSLIYIISLHQEERLTWPKLIF-HVFIIILGVANLIV 557
>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
Length = 472
Score = 36.2 bits (82), Expect = 0.067
Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 2/78 (2%)
Query: 25 PSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISL 84
PS G S P + F T++ ++ +L +G+G+LGL A+ + G++ L
Sbjct: 28 PSRGPAPGSKPVQFMDF--EGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALL 85
Query: 85 LIIGIVAVHCMGILVKCA 102
L I +++ + + +L+ CA
Sbjct: 86 LCIALLSSYSIHLLLTCA 103
Score = 32.7 bits (73), Expect = 0.74
Identities = 34/173 (19%), Positives = 74/173 (42%), Gaps = 23/173 (13%)
Query: 267 FSFEGIGMVLPLENKMKDP--RKFPLILYLGMVIVTILYISLGCLGYLQFGANIQGSITL 324
F+F VLP+ ++ P R+ + + + + +Y GYL F ++++ + L
Sbjct: 267 FAFVCHPEVLPIYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEM-L 325
Query: 325 NLPNCWLYQSVKLLYSIGIFFTYALQFYVPA----------EIIIPFFVSRAPEHCELVV 374
++ + Q L+ + + A+ VP +++ P P H + +
Sbjct: 326 HMYS----QKDPLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPGKAFSWPRHVAIAL 381
Query: 375 DLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSE 427
+L+ L +L I +P + + ++GS S+ +L I+P + + SE
Sbjct: 382 ------ILLVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIVPSE 428
>gi|187423910 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 33.1 bits (74), Expect = 0.57
Identities = 38/176 (21%), Positives = 73/176 (41%), Gaps = 43/176 (24%)
Query: 208 LVFIRNLRALSIF--SLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKT-------- 257
++FI + +LS+ S + NI LV++ I+ S L L+A T
Sbjct: 159 ILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIII------SGLVLLAQGNTKNFDNSFE 212
Query: 258 --------YPLFFGTAIFSFEGIGMVLPLENKMKDP-RKFPLILYLGMVIVTILYISLGC 308
L F +++++G + + ++++P R PL + +G+ +VT YI
Sbjct: 213 GAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYI---- 268
Query: 309 LGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVS 364
+N+ + + +LL S + T+ + PA I+P FV+
Sbjct: 269 --------------LMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVA 310
>gi|7657591 solute carrier family 7, member 9 [Homo sapiens]
Length = 487
Score = 33.1 bits (74), Expect = 0.57
Identities = 38/176 (21%), Positives = 73/176 (41%), Gaps = 43/176 (24%)
Query: 208 LVFIRNLRALSIF--SLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWKT-------- 257
++FI + +LS+ S + NI LV++ I+ S L L+A T
Sbjct: 159 ILFISTVNSLSVRLGSYVQNIFTAAKLVIVAIIII------SGLVLLAQGNTKNFDNSFE 212
Query: 258 --------YPLFFGTAIFSFEGIGMVLPLENKMKDP-RKFPLILYLGMVIVTILYISLGC 308
L F +++++G + + ++++P R PL + +G+ +VT YI
Sbjct: 213 GAQLSVGAISLAFYNGLWAYDGWNQLNYITEELRNPYRNLPLAIIIGIPLVTACYI---- 268
Query: 309 LGYLQFGANIQGSITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVS 364
+N+ + + +LL S + T+ + PA I+P FV+
Sbjct: 269 --------------LMNVSYFTVMTATELLQSQAVAVTFGDRVLYPASWIVPLFVA 310
>gi|110224458 solute carrier family 12, member 6 isoform e [Homo
sapiens]
Length = 1135
Score = 32.3 bits (72), Expect = 0.97
Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 195 RLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPL 251
R+Y +FL +VL+VFI +R ++ F+ L ++VS++ IY ++ P H P+
Sbjct: 304 RVYGTAFLVLMVLVVFI-GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPV 359
>gi|110224456 solute carrier family 12, member 6 isoform d [Homo
sapiens]
Length = 1141
Score = 32.3 bits (72), Expect = 0.97
Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 195 RLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPL 251
R+Y +FL +VL+VFI +R ++ F+ L ++VS++ IY ++ P H P+
Sbjct: 310 RVYGTAFLVLMVLVVFI-GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPV 365
>gi|110224454 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 32.3 bits (72), Expect = 0.97
Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 195 RLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPL 251
R+Y +FL +VL+VFI +R ++ F+ L ++VS++ IY ++ P H P+
Sbjct: 260 RVYGTAFLVLMVLVVFI-GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPV 315
>gi|110224452 solute carrier family 12, member 6 isoform c [Homo
sapiens]
Length = 1091
Score = 32.3 bits (72), Expect = 0.97
Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 195 RLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPL 251
R+Y +FL +VL+VFI +R ++ F+ L ++VS++ IY ++ P H P+
Sbjct: 260 RVYGTAFLVLMVLVVFI-GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPV 315
>gi|4826780 solute carrier family 12, member 6 isoform b [Homo
sapiens]
Length = 1099
Score = 32.3 bits (72), Expect = 0.97
Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 195 RLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPL 251
R+Y +FL +VL+VFI +R ++ F+ L ++VS++ IY ++ P H P+
Sbjct: 268 RVYGTAFLVLMVLVVFI-GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPV 323
>gi|110224449 solute carrier family 12, member 6 isoform a [Homo
sapiens]
Length = 1150
Score = 32.3 bits (72), Expect = 0.97
Identities = 19/57 (33%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Query: 195 RLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPL 251
R+Y +FL +VL+VFI +R ++ F+ L ++VS++ IY ++ P H P+
Sbjct: 319 RVYGTAFLVLMVLVVFI-GVRYVNKFASLFLACVIVSILAIYAGAIKSSFAPPHFPV 374
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 32.0 bits (71), Expect = 1.3
Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 15/106 (14%)
Query: 380 TVLVCLTCILAILIPR-----------LDLVISL-VGSVSSSALALIIPPLLEVTTFYSE 427
T+L+CL + +L+ L +SL VG+++ A+ + P +L + T E
Sbjct: 309 TLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEE 368
Query: 428 GMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTC 473
G+SP ++ L + G F + +E L+ L+ P + + C
Sbjct: 369 GLSPQPTWR-LLAMLAGLYAFFL--FENLFNLLLPRDPEDLEDGPC 411
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 32.0 bits (71), Expect = 1.3
Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 15/106 (14%)
Query: 380 TVLVCLTCILAILIPR-----------LDLVISL-VGSVSSSALALIIPPLLEVTTFYSE 427
T+L+CL + +L+ L +SL VG+++ A+ + P +L + T E
Sbjct: 334 TLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEE 393
Query: 428 GMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTC 473
G+SP ++ L + G F + +E L+ L+ P + + C
Sbjct: 394 GLSPQPTWR-LLAMLAGLYAFFL--FENLFNLLLPRDPEDLEDGPC 436
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.144 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,825,427
Number of Sequences: 37866
Number of extensions: 709697
Number of successful extensions: 2217
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 2173
Number of HSP's gapped (non-prelim): 63
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.