Guide to the Human Genome
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Search of human proteins with 41352718

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41352718 deltex homolog 1 [Homo sapiens]
         (620 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41352718 deltex homolog 1 [Homo sapiens]                          1306   0.0  
gi|148237498 deltex 4 homolog [Homo sapiens]                          811   0.0  
gi|156564384 deltex 2 isoform a [Homo sapiens]                        524   e-148
gi|156564382 deltex 2 isoform a [Homo sapiens]                        524   e-148
gi|156564380 deltex 2 isoform a [Homo sapiens]                        524   e-148
gi|156564386 deltex 2 isoform b [Homo sapiens]                        481   e-135
gi|19923717 deltex 3-like [Homo sapiens]                              149   7e-36
gi|30425428 deltex homolog 3 [Homo sapiens]                           120   4e-27
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]                     66   8e-11
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]                     66   8e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    59   1e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    58   3e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   4e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     57   7e-08
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    55   1e-07
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    55   2e-07
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    55   3e-07
gi|160707881 formin 2 [Homo sapiens]                                   55   3e-07
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               54   3e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  53   1e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   1e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   1e-06
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    52   2e-06
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    52   2e-06
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    52   2e-06
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    52   2e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                52   2e-06
gi|39812378 RAN binding protein 9 [Homo sapiens]                       52   2e-06
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                52   2e-06
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                52   2e-06

>gi|41352718 deltex homolog 1 [Homo sapiens]
          Length = 620

 Score = 1306 bits (3381), Expect = 0.0
 Identities = 620/620 (100%), Positives = 620/620 (100%)

Query: 1   MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV 60
           MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV
Sbjct: 1   MSRPGHGGLMPVNGLGFPPQNVARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDARGSV 60

Query: 61  VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA 120
           VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA
Sbjct: 61  VLGQVDAQLVPYIIDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTA 120

Query: 121 YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT 180
           YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT
Sbjct: 121 YDMDICITIQNAYEKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLT 180

Query: 181 VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG 240
           VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG
Sbjct: 181 VGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG 240

Query: 241 PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ 300
           PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ
Sbjct: 241 PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQ 300

Query: 301 RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP 360
           RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP
Sbjct: 301 RTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP 360

Query: 361 PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT 420
           PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT
Sbjct: 361 PPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVT 420

Query: 421 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG 480
           ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG
Sbjct: 421 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG 480

Query: 481 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN 540
           TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN
Sbjct: 481 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN 540

Query: 541 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY 600
           NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY
Sbjct: 541 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY 600

Query: 601 LDNVLAELTAQGVSEAAAKA 620
           LDNVLAELTAQGVSEAAAKA
Sbjct: 601 LDNVLAELTAQGVSEAAAKA 620


>gi|148237498 deltex 4 homolog [Homo sapiens]
          Length = 619

 Score =  811 bits (2094), Expect = 0.0
 Identities = 393/610 (64%), Positives = 466/610 (76%), Gaps = 24/610 (3%)

Query: 25  VVVWEWLNEHSRWRPYTATVCHHIENVLKEDAR--GSVVLGQVDAQLVPYIIDLQSMHQF 82
           VVVWEWLNEH RWRPY+  V HHIE V++   R  GSVVLGQVD++L PYIIDLQSM+QF
Sbjct: 7   VVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGGSVVLGQVDSRLAPYIIDLQSMNQF 66

Query: 83  RQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTAYDMDICITIQNAYEKQHPWLDL 142
           RQDTGT+RPVRRN+YDPSSAPGKG+VWEWEND G+WT YDM++ ITIQ+AYEKQHPW+DL
Sbjct: 67  RQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQHPWIDL 126

Query: 143 SSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVGASSG----- 197
           +S+GF Y+I FN+M Q+NRQT+R+RR+RRRLDL YP+  G++PK+QSWPV          
Sbjct: 127 TSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGPATSPPM 186

Query: 198 QPCSCQQCLLVNSTRAA------SNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSA 251
            PCSC QC+LV S +AA          L   R+  PP   +  PP PG   GA  +  + 
Sbjct: 187 SPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGS--GAKPLDSTG 244

Query: 252 TFTGAALWAAPAAGPAEPAP--PPGAPPRSPGAPGGARTPGQN----NLNRPGPQRTTSV 305
           T  G  L  AP+      A   P G    SP +P G  +         LNR   QR    
Sbjct: 245 TIRGP-LKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIA 303

Query: 306 SARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSK 365
            +R  I  GVP +PVKNLNG+ PV+PALAG+TGIL+ AAGLPVCLTR PK +LHPPPVSK
Sbjct: 304 QSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPPVSK 363

Query: 366 SDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVTASGYE 425
           S++K +PGV    RKT KK  KK K PE+V+++Y+QKV++PPDEDCTICMERL   SGY+
Sbjct: 364 SEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPSGYK 423

Query: 426 GVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPG 485
           G      V+P+LVG+L RCGH+YH+ CLVAMY+NGNKDGSLQCPTCK IYG KTGTQPPG
Sbjct: 424 GP--QPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPPG 481

Query: 486 KMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGR 545
           KME+HLIPHSLPG PD +TIRI+Y IP GIQGPEHPNPGK F+ARGFPRHCYLP++EKGR
Sbjct: 482 KMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKGR 541

Query: 546 KVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVL 605
           KVL+LL+ AW+RRLIF IGTS+TTGESDTV+WNE+HHKTEFGSNLTGHGYPDA+YLDNVL
Sbjct: 542 KVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVL 601

Query: 606 AELTAQGVSE 615
           AEL AQG+SE
Sbjct: 602 AELAAQGISE 611


>gi|156564384 deltex 2 isoform a [Homo sapiens]
          Length = 622

 Score =  524 bits (1349), Expect = e-148
 Identities = 292/615 (47%), Positives = 364/615 (59%), Gaps = 37/615 (6%)

Query: 23  ARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDA---------RGSVVLGQVDAQLVPYI 73
           A V VWEW +    W PY+ATVC  IE    +             S+ LGQ D  L PYI
Sbjct: 17  AAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYI 76

Query: 74  IDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTAYDMDICITIQNAY 133
           IDL S  QFRQDTGTMR VRR+ +   SAPG+G+VWEW +D G+WTAY+  +C  ++   
Sbjct: 77  IDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGSWTAYEASVCDYLEQQV 136

Query: 134 EKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVG 193
            + +  +DL+ LG+ Y + + + +Q N+ +   R +RR+    YP+T    P   +    
Sbjct: 137 ARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHT---- 192

Query: 194 ASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATF 253
              G  CSC QCL  + T   S     S      PA P+P  PP          +  A +
Sbjct: 193 ---GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYPVPQHPPHRTASVFGTHQAFAPY 247

Query: 254 TGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQR-----TTSVSAR 308
              +L  A +A         GA P S G+    R+    +L+  GPQ      +TS +  
Sbjct: 248 NKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRS----SLSHLGPQHLPPGSSTSGAVS 303

Query: 309 ASIPPG-------VPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPP 361
           AS+P G       VPA     +     V  ALAGMT +L+ A GLPVCL+RAP+P    P
Sbjct: 304 ASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAIGLPVCLSRAPQPT--SP 361

Query: 362 PVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPEDVVRRYMQKVKNPPDEDCTICMERLVT 420
           P S+   K    V  + + + K    K +  PE V++ Y +++K PPDEDC ICME+L T
Sbjct: 362 PASRLASKSHGSVKRLRKMSVKGATPKPEPEPEQVIKNYTEELKVPPDEDCIICMEKLST 421

Query: 421 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG 480
           ASGY  V   K +    VG L +C H +HLLCL+AMY NGNKDGSLQCP+CK IYGEKTG
Sbjct: 422 ASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTG 481

Query: 481 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN 540
           TQP GKME      SLPG  D  TI IVY IP GIQGPEHPNPGK FTARGFPR CYLP+
Sbjct: 482 TQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPD 541

Query: 541 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY 600
           N +GRKVL LL  AW+RRLIFT+GTS+TTGE+DTVVWNEIHHKTE   N+TGHGYPD +Y
Sbjct: 542 NAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNY 601

Query: 601 LDNVLAELTAQGVSE 615
           L NVLAEL AQGV+E
Sbjct: 602 LQNVLAELAAQGVTE 616


>gi|156564382 deltex 2 isoform a [Homo sapiens]
          Length = 622

 Score =  524 bits (1349), Expect = e-148
 Identities = 292/615 (47%), Positives = 364/615 (59%), Gaps = 37/615 (6%)

Query: 23  ARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDA---------RGSVVLGQVDAQLVPYI 73
           A V VWEW +    W PY+ATVC  IE    +             S+ LGQ D  L PYI
Sbjct: 17  AAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYI 76

Query: 74  IDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTAYDMDICITIQNAY 133
           IDL S  QFRQDTGTMR VRR+ +   SAPG+G+VWEW +D G+WTAY+  +C  ++   
Sbjct: 77  IDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGSWTAYEASVCDYLEQQV 136

Query: 134 EKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVG 193
            + +  +DL+ LG+ Y + + + +Q N+ +   R +RR+    YP+T    P   +    
Sbjct: 137 ARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHT---- 192

Query: 194 ASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATF 253
              G  CSC QCL  + T   S     S      PA P+P  PP          +  A +
Sbjct: 193 ---GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYPVPQHPPHRTASVFGTHQAFAPY 247

Query: 254 TGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQR-----TTSVSAR 308
              +L  A +A         GA P S G+    R+    +L+  GPQ      +TS +  
Sbjct: 248 NKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRS----SLSHLGPQHLPPGSSTSGAVS 303

Query: 309 ASIPPG-------VPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPP 361
           AS+P G       VPA     +     V  ALAGMT +L+ A GLPVCL+RAP+P    P
Sbjct: 304 ASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAIGLPVCLSRAPQPT--SP 361

Query: 362 PVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPEDVVRRYMQKVKNPPDEDCTICMERLVT 420
           P S+   K    V  + + + K    K +  PE V++ Y +++K PPDEDC ICME+L T
Sbjct: 362 PASRLASKSHGSVKRLRKMSVKGATPKPEPEPEQVIKNYTEELKVPPDEDCIICMEKLST 421

Query: 421 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG 480
           ASGY  V   K +    VG L +C H +HLLCL+AMY NGNKDGSLQCP+CK IYGEKTG
Sbjct: 422 ASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTG 481

Query: 481 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN 540
           TQP GKME      SLPG  D  TI IVY IP GIQGPEHPNPGK FTARGFPR CYLP+
Sbjct: 482 TQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPD 541

Query: 541 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY 600
           N +GRKVL LL  AW+RRLIFT+GTS+TTGE+DTVVWNEIHHKTE   N+TGHGYPD +Y
Sbjct: 542 NAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNY 601

Query: 601 LDNVLAELTAQGVSE 615
           L NVLAEL AQGV+E
Sbjct: 602 LQNVLAELAAQGVTE 616


>gi|156564380 deltex 2 isoform a [Homo sapiens]
          Length = 622

 Score =  524 bits (1349), Expect = e-148
 Identities = 292/615 (47%), Positives = 364/615 (59%), Gaps = 37/615 (6%)

Query: 23  ARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDA---------RGSVVLGQVDAQLVPYI 73
           A V VWEW +    W PY+ATVC  IE    +             S+ LGQ D  L PYI
Sbjct: 17  AAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYI 76

Query: 74  IDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTAYDMDICITIQNAY 133
           IDL S  QFRQDTGTMR VRR+ +   SAPG+G+VWEW +D G+WTAY+  +C  ++   
Sbjct: 77  IDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGSWTAYEASVCDYLEQQV 136

Query: 134 EKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVG 193
            + +  +DL+ LG+ Y + + + +Q N+ +   R +RR+    YP+T    P   +    
Sbjct: 137 ARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHT---- 192

Query: 194 ASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATF 253
              G  CSC QCL  + T   S     S      PA P+P  PP          +  A +
Sbjct: 193 ---GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYPVPQHPPHRTASVFGTHQAFAPY 247

Query: 254 TGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQR-----TTSVSAR 308
              +L  A +A         GA P S G+    R+    +L+  GPQ      +TS +  
Sbjct: 248 NKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRS----SLSHLGPQHLPPGSSTSGAVS 303

Query: 309 ASIPPG-------VPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPP 361
           AS+P G       VPA     +     V  ALAGMT +L+ A GLPVCL+RAP+P    P
Sbjct: 304 ASLPSGPSSSPGSVPATVPMQMPKPSRVQQALAGMTSVLMSAIGLPVCLSRAPQPT--SP 361

Query: 362 PVSKSDVKPVPGVPGVCRKTKKKHLKKSK-NPEDVVRRYMQKVKNPPDEDCTICMERLVT 420
           P S+   K    V  + + + K    K +  PE V++ Y +++K PPDEDC ICME+L T
Sbjct: 362 PASRLASKSHGSVKRLRKMSVKGATPKPEPEPEQVIKNYTEELKVPPDEDCIICMEKLST 421

Query: 421 ASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTG 480
           ASGY  V   K +    VG L +C H +HLLCL+AMY NGNKDGSLQCP+CK IYGEKTG
Sbjct: 422 ASGYSDVTDSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTG 481

Query: 481 TQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPN 540
           TQP GKME      SLPG  D  TI IVY IP GIQGPEHPNPGK FTARGFPR CYLP+
Sbjct: 482 TQPQGKMEVLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPD 541

Query: 541 NEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASY 600
           N +GRKVL LL  AW+RRLIFT+GTS+TTGE+DTVVWNEIHHKTE   N+TGHGYPD +Y
Sbjct: 542 NAQGRKVLELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNY 601

Query: 601 LDNVLAELTAQGVSE 615
           L NVLAEL AQGV+E
Sbjct: 602 LQNVLAELAAQGVTE 616


>gi|156564386 deltex 2 isoform b [Homo sapiens]
          Length = 575

 Score =  481 bits (1237), Expect = e-135
 Identities = 275/607 (45%), Positives = 342/607 (56%), Gaps = 68/607 (11%)

Query: 23  ARVVVWEWLNEHSRWRPYTATVCHHIENVLKEDA---------RGSVVLGQVDAQLVPYI 73
           A V VWEW +    W PY+ATVC  IE    +             S+ LGQ D  L PYI
Sbjct: 17  AAVAVWEWQDGLGTWHPYSATVCSFIEQQFVQQKGQRFGLGSLAHSIPLGQADPSLAPYI 76

Query: 74  IDLQSMHQFRQDTGTMRPVRRNFYDPSSAPGKGIVWEWENDGGAWTAYDMDICITIQNAY 133
           IDL S  QFRQDTGTMR VRR+ +   SAPG+G+VWEW +D G+WTAY+  +C  ++   
Sbjct: 77  IDLPSWTQFRQDTGTMRAVRRHLFPQHSAPGRGVVWEWLSDDGSWTAYEASVCDYLEQQV 136

Query: 134 EKQHPWLDLSSLGFCYLIYFNSMSQMNRQTRRRRRLRRRLDLAYPLTVGSIPKSQSWPVG 193
            + +  +DL+ LG+ Y + + + +Q N+ +   R +RR+    YP+T    P   +    
Sbjct: 137 ARGNQLVDLAPLGYNYTVNYTTHTQTNKTSSFCRSVRRQAGPPYPVTTIIAPPGHT---- 192

Query: 194 ASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATF 253
              G  CSC QCL  + T   S     S      PA P+P  PP          +  A +
Sbjct: 193 ---GVACSCHQCLSGSRTGPVSGRYRHSMTNL--PAYPVPQHPPHRTASVFGTHQAFAPY 247

Query: 254 TGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQR-----TTSVSAR 308
              +L  A +A         GA P S G+    R+    +L+  GPQ      +TS +  
Sbjct: 248 NKPSLSGARSAPRLNTTNAWGAAPPSLGSQPLYRS----SLSHLGPQHLPPGSSTSGAVS 303

Query: 309 ASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDV 368
           AS+P G  + P       G V PA   M               + PKP      ++ +  
Sbjct: 304 ASLPSGPSSSP-------GSV-PATVPM---------------QMPKPSRVQQALAGATP 340

Query: 369 KPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPPDEDCTICMERLVTASGYEGVL 428
           KP P                   PE V++ Y +++K PPDEDC ICME+L TASGY  V 
Sbjct: 341 KPEP------------------EPEQVIKNYTEELKVPPDEDCIICMEKLSTASGYSDVT 382

Query: 429 RHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQCPTCKAIYGEKTGTQPPGKME 488
             K +    VG L +C H +HLLCL+AMY NGNKDGSLQCP+CK IYGEKTGTQP GKME
Sbjct: 383 DSKAIGSLAVGHLTKCSHAFHLLCLLAMYCNGNKDGSLQCPSCKTIYGEKTGTQPQGKME 442

Query: 489 FHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFTARGFPRHCYLPNNEKGRKVL 548
                 SLPG  D  TI IVY IP GIQGPEHPNPGK FTARGFPR CYLP+N +GRKVL
Sbjct: 443 VLRFQMSLPGHEDCGTILIVYSIPHGIQGPEHPNPGKPFTARGFPRQCYLPDNAQGRKVL 502

Query: 549 RLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGSNLTGHGYPDASYLDNVLAEL 608
            LL  AW+RRLIFT+GTS+TTGE+DTVVWNEIHHKTE   N+TGHGYPD +YL NVLAEL
Sbjct: 503 ELLKVAWKRRLIFTVGTSSTTGETDTVVWNEIHHKTEMDRNITGHGYPDPNYLQNVLAEL 562

Query: 609 TAQGVSE 615
            AQGV+E
Sbjct: 563 AAQGVTE 569


>gi|19923717 deltex 3-like [Homo sapiens]
          Length = 740

 Score =  149 bits (376), Expect = 7e-36
 Identities = 85/205 (41%), Positives = 113/205 (55%), Gaps = 28/205 (13%)

Query: 411 CTICMERLVTASGYEGVLRHKGVRPELVGRLGRCGHMYHLLCLVAMYSNGNKDGSLQ--C 468
           C ICM+           + +K V P       +C H +   C+       NK  S +  C
Sbjct: 561 CVICMD----------TISNKKVLP-------KCKHEFCAPCI-------NKAMSYKPIC 596

Query: 469 PTCKAIYGEKTGTQPPGKMEFHLIPHSLPGFPDTQTIRIVYDIPTGIQGPEHPNPGKKFT 528
           PTC+  YG + G QP G M F +   SLPG+    TI I Y +  GIQ  EHPNPGK++ 
Sbjct: 597 PTCQTSYGIQKGNQPEGSMVFTVSRDSLPGYESFGTIVITYSMKAGIQTEEHPNPGKRYP 656

Query: 529 ARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHHKTEFGS 588
             G  R  YLP+N++GRKVL+LL  A++++LIFT+G S   G SD + WN+IHHKT    
Sbjct: 657 --GIQRTAYLPDNKEGRKVLKLLYRAFDQKLIFTVGYSRVLGVSDVITWNDIHHKTSRFG 714

Query: 589 NLTGHGYPDASYLDNVLAELTAQGV 613
               +GYPD SYL  V  EL A+G+
Sbjct: 715 GPEMYGYPDPSYLKRVKEELKAKGI 739


>gi|30425428 deltex homolog 3 [Homo sapiens]
          Length = 347

 Score =  120 bits (301), Expect = 4e-27
 Identities = 67/153 (43%), Positives = 87/153 (56%), Gaps = 10/153 (6%)

Query: 468 CPTCKAIYGEKTGTQPP-GKMEFHLIPHS----LPGFPDTQTIRIVYDIPTGIQGPEHPN 522
           CP C   YG+  G QP  G+M   L+       LP +    TI I Y  P G+QG EHPN
Sbjct: 199 CPMCGRFYGQLVGNQPQNGRM---LVSKDATLLLPSYEKYGTIVIQYVFPPGVQGAEHPN 255

Query: 523 PGKKFTARGFPRHCYLPNNEKGRKVLRLLITAWERRLIFTIGTSNTTGESDTVVWNEIHH 582
           PG ++   G  R  YLP+  +G KVL L   A+++RL FTIGTS TTG  + + WN+IHH
Sbjct: 256 PGVRYP--GTTRVAYLPDCPEGNKVLTLFRKAFDQRLTFTIGTSMTTGRPNVITWNDIHH 313

Query: 583 KTEFGSNLTGHGYPDASYLDNVLAELTAQGVSE 615
           KT         GYPD +YL  V  EL A+G+++
Sbjct: 314 KTSCTGGPQLFGYPDPTYLTRVQEELRAKGITD 346


>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
          Length = 1263

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 50/151 (33%), Positives = 58/151 (38%), Gaps = 20/151 (13%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA 286
           PP PP PPPPPP  P G     P +   G A+   P        PPP   P   G P  +
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 658

Query: 287 RTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGL 346
             PG   +  P P     +   A IPP  P LP     G  P  P L G  G+      L
Sbjct: 659 SLPGGTAIPPPPP-----LPGSARIPPPPPPLP--GSAGIPPPPPPLPGEAGMPPPPPPL 711

Query: 347 PVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
           P        P + PPP       P PG PG+
Sbjct: 712 P------GGPGIPPPP-------PFPGGPGI 729



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 54/173 (31%), Positives = 67/173 (38%), Gaps = 45/173 (26%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPA-EPAPPPGAPPRSPGAPGG 285
           P   P+PP PP  G  G +   P            PA G +  P PPP  PP  P  PGG
Sbjct: 568 PSRAPVPPAPPLPGDSGTIIPPP------------PAPGDSTTPPPPPPPPPPPPPLPGG 615

Query: 286 A------RTPGQNNLNRPGPQRTTSVSARASIPP--------GVPALPVKNLNGTG-PVH 330
                    PG   ++ P P     +S  A+IPP        G+P+ P     GT  P  
Sbjct: 616 VCISSPPSLPGGTAISPPPP-----LSGDATIPPPPPLPEGVGIPS-PSSLPGGTAIPPP 669

Query: 331 PALAGMTGI------LLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
           P L G   I      L  +AG+P      P     PPP       P+PG PG+
Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP-----PPPLPGGPGI 717



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 35/104 (33%), Positives = 39/104 (37%), Gaps = 27/104 (25%)

Query: 227 PPAPPLPP----PPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGA 282
           PP PPLP     PPPP   PG+  + P            P  G A   PPP   P  PG 
Sbjct: 667 PPPPPLPGSARIPPPPPPLPGSAGIPPPPP---------PLPGEAGMPPPPPPLPGGPGI 717

Query: 283 PGGARTPGQNNLNRPGPQRTTSVSARASIPP------GVPALPV 320
           P     PG   +  P P           +PP      GVPA PV
Sbjct: 718 PPPPPFPGGPGIPPPPP--------GMGMPPPPPFGFGVPAAPV 753


>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
          Length = 1272

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 50/151 (33%), Positives = 58/151 (38%), Gaps = 20/151 (13%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA 286
           PP PP PPPPPP  P G     P +   G A+   P        PPP   P   G P  +
Sbjct: 608 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPS 667

Query: 287 RTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGL 346
             PG   +  P P     +   A IPP  P LP     G  P  P L G  G+      L
Sbjct: 668 SLPGGTAIPPPPP-----LPGSARIPPPPPPLP--GSAGIPPPPPPLPGEAGMPPPPPPL 720

Query: 347 PVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
           P        P + PPP       P PG PG+
Sbjct: 721 P------GGPGIPPPP-------PFPGGPGI 738



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 54/173 (31%), Positives = 67/173 (38%), Gaps = 45/173 (26%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPA-EPAPPPGAPPRSPGAPGG 285
           P   P+PP PP  G  G +   P            PA G +  P PPP  PP  P  PGG
Sbjct: 577 PSRAPVPPAPPLPGDSGTIIPPP------------PAPGDSTTPPPPPPPPPPPPPLPGG 624

Query: 286 A------RTPGQNNLNRPGPQRTTSVSARASIPP--------GVPALPVKNLNGTG-PVH 330
                    PG   ++ P P     +S  A+IPP        G+P+ P     GT  P  
Sbjct: 625 VCISSPPSLPGGTAISPPPP-----LSGDATIPPPPPLPEGVGIPS-PSSLPGGTAIPPP 678

Query: 331 PALAGMTGI------LLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
           P L G   I      L  +AG+P      P     PPP       P+PG PG+
Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPP-----PPPLPGGPGI 726



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 35/104 (33%), Positives = 39/104 (37%), Gaps = 27/104 (25%)

Query: 227 PPAPPLPP----PPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGA 282
           PP PPLP     PPPP   PG+  + P            P  G A   PPP   P  PG 
Sbjct: 676 PPPPPLPGSARIPPPPPPLPGSAGIPPPPP---------PLPGEAGMPPPPPPLPGGPGI 726

Query: 283 PGGARTPGQNNLNRPGPQRTTSVSARASIPP------GVPALPV 320
           P     PG   +  P P           +PP      GVPA PV
Sbjct: 727 PPPPPFPGGPGIPPPPP--------GMGMPPPPPFGFGVPAAPV 762


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 55/167 (32%), Positives = 66/167 (39%), Gaps = 32/167 (19%)

Query: 221 SQRRKAPPAPPLPPP----PPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPG-- 274
           S RR   PA P PP     PPP G  G+ A  P+A    AA+ A P   PA PA P G  
Sbjct: 109 SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAA----AAVAAGPEPAPAGPAKPAGPA 164

Query: 275 ------APPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGP 328
                  P   PG PG    PG      PG  +T + SA A +     A P  +L   GP
Sbjct: 165 ALAARAGPGPGPG-PGPGPGPGPGKPAGPGAAQTLNGSA-ALLNSHHAAAPAVSLVNNGP 222

Query: 329 VHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
                         AA LP+    AP  ++  PP   +   P P  P
Sbjct: 223 --------------AALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP 255



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 53/196 (27%), Positives = 69/196 (35%), Gaps = 15/196 (7%)

Query: 226 APPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPA--AGP--AEPAPPPGAPPRSPG 281
           APPAP  P PP    P    A  P      A L   P   AGP  A PA PP A  ++ G
Sbjct: 248 APPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGG 307

Query: 282 APGGARTPGQNNLNRPGPQRTTSVSARASIP-PGVPALPVKNLNGTGPVHPALAGMTGIL 340
           + G A  P        G        A A+ P PGV A   K +    P        +G  
Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPA 367

Query: 341 LCAAGL---PVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKK-------HLKKSK 390
             AA +   P      P P   PPP   +      G  G   ++  +        ++ + 
Sbjct: 368 STAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATL 427

Query: 391 NPEDVVRRYMQKVKNP 406
            P  +  R  Q  +NP
Sbjct: 428 TPTVLAPRLPQPPQNP 443



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 52/180 (28%), Positives = 67/180 (37%), Gaps = 21/180 (11%)

Query: 191 PVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAP-PLPPPPPPGGPPGALAVRP 249
           P G  + Q  +    LL NS  AA+ A+  S     P A  PLP P  PG       V  
Sbjct: 189 PAGPGAAQTLNGSAALL-NSHHAAAPAV--SLVNNGPAALLPLPKPAAPG------TVIQ 239

Query: 250 SATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARA 309
           +  F GAA   APAA    P+PP    P +P A      P    L RP        +A  
Sbjct: 240 TPPFVGAAAPPAPAA----PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295

Query: 310 SIPPGVPALPVKNLNGTGPVHPALAGMTGI-------LLCAAGLPVCLTRAPKPILHPPP 362
           ++PP   A    +        PA  G  G+          AA  P     +PK ++   P
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP 355



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 49/183 (26%), Positives = 63/183 (34%), Gaps = 39/183 (21%)

Query: 227 PPAPPLP-----PPPPPGGPPGALAV--RPSATFTGAALWAAPAAGPAE----------- 268
           PP PP P     PP  P GPP A      P+A   G +  AAPA  PA            
Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330

Query: 269 -----PAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTT-----------SVSARASIP 312
                 AP PG    SP     A  P    L   GP  T            ++ + A++P
Sbjct: 331 PGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP 390

Query: 313 PGVPALPVKNLNG-TGPVHPALA----GMTGILLCAAGLPVCLTRAPKPILHPPPVSKSD 367
           P  P  P     G  G V  +L+      T  +       V   R P+P  +P  +    
Sbjct: 391 PPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQ 450

Query: 368 VKP 370
           + P
Sbjct: 451 LPP 453



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 52/174 (29%), Positives = 59/174 (33%), Gaps = 25/174 (14%)

Query: 207 LVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGP 266
           LV S  +   A  A     AP  P +          GAL     +     A  A PAA P
Sbjct: 25  LVGSLESQLAASAAHHHHLAPRTPEVR-----AAAAGALGNHVVSGSPAGAAGAGPAA-P 78

Query: 267 AEPAP--PPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLN 324
           AE AP   P  PP     PGG            GPQR    S R  + P  PA P   L 
Sbjct: 79  AEGAPGAAPEPPPAGRARPGGG-----------GPQRPGPPSPRRPLVPAGPAPPAAKLR 127

Query: 325 GTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHP--PPVSKSDVKPVPGVPG 376
              P     AG    +  AA +      AP     P  P    +   P PG PG
Sbjct: 128 ---PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG-PG 177



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 50/198 (25%), Positives = 73/198 (36%), Gaps = 51/198 (25%)

Query: 199 PCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPG-----------ALAV 247
           P + Q          A++ ++    + A P+P   PPP PG P G           +L+ 
Sbjct: 355 PPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSR 414

Query: 248 RPSATFTGAALWAAPAA-GPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVS 306
            P+AT +G      P    P  P P                           PQ  T++ 
Sbjct: 415 TPTATTSGIRATLTPTVLAPRLPQP---------------------------PQNPTNIQ 447

Query: 307 ARASIPPGVPALPVKNLNGTGPVHP--ALAGMTGILLCAAGLPVCLTRAPKPI--LHPPP 362
               +PPG+  + V++ NG   + P  ALA M       A      T AP+P      PP
Sbjct: 448 -NFQLPPGM--VLVRSENGQLLMIPQQALAQMQ----AQAHAQPQTTMAPRPATPTSAPP 500

Query: 363 VSKSDVKPVPGVPGVCRK 380
           V  S V+  PG P + R+
Sbjct: 501 VQISTVQ-APGTPIIARQ 517


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 54/173 (31%), Positives = 66/173 (38%), Gaps = 19/173 (10%)

Query: 221 SQRRKAPPAPPLPPPPPPGGPPGALAV---RP----SATFT---------GAALWAAPAA 264
           S  R+ PP PP PPPPP   PP A A    RP    +  FT          + L   P  
Sbjct: 613 SLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLG 672

Query: 265 GPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRP--GPQRTTSVSARASIPPGVPALPVKN 322
            P  P P P     SP  P        N+L+ P   P  TT V A  S P G PAL    
Sbjct: 673 APEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVS-PHGAPALSNGP 731

Query: 323 LNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
                 + P  A  T +L  A   P    + P      PP+ K+ +  V  +P
Sbjct: 732 QTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLP 784



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 32/97 (32%), Positives = 38/97 (39%), Gaps = 19/97 (19%)

Query: 226 APPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAP---PRSPGA 282
           +PP P  PPPPPP  PP   +  P            PA    E +PPP  P    R  G 
Sbjct: 423 SPPPPLCPPPPPPVSPPPLPSPPP-----------PPAQEEQEESPPPVVPATCSRKRGR 471

Query: 283 PGGARTPGQ---NNLNRPGPQRTTSVSARASIPPGVP 316
           P    TP Q       R GP+ T+  +   S   G P
Sbjct: 472 P--PLTPSQRAEREAARAGPEGTSPPTPTPSTATGGP 506



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 29/100 (29%), Positives = 41/100 (41%), Gaps = 10/100 (10%)

Query: 233  PPPPPPGGPPGALAVRPSATFT-----GAALWAAPAAGPAEPAPPPGAPPRSPGAPGGAR 287
            P PPP   PP    + P+A  +     G  L   P  G   PAPPP  PP +     G  
Sbjct: 2210 PVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPA 2269

Query: 288  TPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTG 327
            +P +  +     +R ++ S R+  PP  P      L+  G
Sbjct: 2270 SPPRQAIR---VKRVSTFSGRS--PPAPPPYKAPRLDEDG 2304



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 34/126 (26%), Positives = 42/126 (33%), Gaps = 27/126 (21%)

Query: 222 QRRKAPP---APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPR 278
           +  K PP    PP P PPPP  PP                  +P      P PPP +PP 
Sbjct: 397 EEAKLPPPPLTPPAPSPPPPLPPPS----------------TSPPPPLCPPPPPPVSPPP 440

Query: 279 SPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVK------NLNGTGPVHPA 332
            P  P       Q     P P    + S +   PP  P+   +         GT P  P 
Sbjct: 441 LPSPPPPPAQEEQE--ESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498

Query: 333 LAGMTG 338
            +  TG
Sbjct: 499 PSTATG 504



 Score = 36.6 bits (83), Expect = 0.071
 Identities = 47/183 (25%), Positives = 63/183 (34%), Gaps = 38/183 (20%)

Query: 213 AASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP 272
           A S+ ++ + RR     PP PP            +RP  T +           P EPAP 
Sbjct: 534 ARSSRVIKTPRRFMDEDPPKPPKVEVSP-----VLRPPITTSPPV--------PQEPAPV 580

Query: 273 PGAP--PRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVH 330
           P  P  P  P  P       ++ L  P   R TS++     PP  P  P      + P  
Sbjct: 581 PSPPRAPTPPSTPVPLPEKRRSILREP-TFRWTSLTRELPPPPPAPPPPPA---PSPPPA 636

Query: 331 PALAGMTGILLCAAGL-----------------PVCLTRAPKPILHPPPVSKSDVKPVPG 373
           PA +    +LL A                    P+    AP+P   PPP   S  +P P 
Sbjct: 637 PATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP--EPPPADDSPAEPEPR 694

Query: 374 VPG 376
             G
Sbjct: 695 AVG 697



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 18/59 (30%)

Query: 228  PAPPLPPPP--------PPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPR 278
            PAPP PPPP        P   P  A+ V+  +TF+G           + PAPPP   PR
Sbjct: 2251 PAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGR----------SPPAPPPYKAPR 2299



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 10/70 (14%)

Query: 230  PPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTP 289
            P  P PP     P  LA RP       + WA+P   P + +P    PP  P +   A TP
Sbjct: 1904 PDFPAPPRRSRRPSPLAPRPP-----PSRWASP---PLKTSPQLRVPP--PTSVVTALTP 1953

Query: 290  GQNNLNRPGP 299
                L  PGP
Sbjct: 1954 TSGELAPPGP 1963



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 36/140 (25%), Positives = 50/140 (35%), Gaps = 5/140 (3%)

Query: 191  PVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPS 250
            P    +  P      L V    +   A+  +    APP P   PPPP    P    +   
Sbjct: 1924 PPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVV 1983

Query: 251  ATFTGAAL-WAAPAAGP---AEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVS 306
            +  + A L +AA   G     E     GA   S G PG +     +  +R      T VS
Sbjct: 1984 SGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVS 2043

Query: 307  ARASIPPGVPALP-VKNLNG 325
            A    P   P  P ++ L+G
Sbjct: 2044 APGLAPSATPGAPRIEQLDG 2063



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 37/133 (27%), Positives = 45/133 (33%), Gaps = 33/133 (24%)

Query: 219 LASQRRKAP-------PAPPLPPP------PPPGGPPGALAVRPSATFTGAALWA----- 260
           L SQR +AP          PLPPP      P P   P              AL       
Sbjct: 141 LRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRA 200

Query: 261 ----APAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIP---P 313
               AP +   EP+ P  +  R PG P G          R   Q      A  +IP   P
Sbjct: 201 QAPQAPRSRACEPSTPRRSRGRPPGRPAGP--------CRRKQQAVVVAEAAVTIPKPEP 252

Query: 314 GVPALPVKNLNGT 326
             P +PVK+  G+
Sbjct: 253 PPPVVPVKHQTGS 265



 Score = 29.6 bits (65), Expect = 8.6
 Identities = 20/62 (32%), Positives = 22/62 (35%), Gaps = 4/62 (6%)

Query: 220  ASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATF---TGAALWAAPAAGP-AEPAPPPGA 275
            A  RR   P+P  P PPP       L   P       T       P +G  A P P P  
Sbjct: 1908 APPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSP 1967

Query: 276  PP 277
            PP
Sbjct: 1968 PP 1969


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 51/178 (28%), Positives = 64/178 (35%), Gaps = 4/178 (2%)

Query: 191 PVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPS 250
           P+ A    P S     L   +  A NA+     +     PP PP   P  PP +  V PS
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688

Query: 251 ATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTP----GQNNLNRPGPQRTTSVS 306
           AT    A  +  A     P  PP +PP SP A    + P           P P  +  +S
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMS 748

Query: 307 ARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVS 364
             A+ PP VP L         P  PA   M+ +       P  L   P   L  PP S
Sbjct: 749 PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPAS 806



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 50/182 (27%), Positives = 70/182 (38%), Gaps = 27/182 (14%)

Query: 219 LASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAE-PAPPPGAPP 277
           LA    +APP+PP  PP  P   P   A    A     A ++ P + P + P  PP +PP
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 278 RSPGA------------------PGGARTPGQNNLNRPGPQRTTSVSA-RASIPPGVPAL 318
            SP A                  P    +P  +    P PQ    ++A    +PP  PA 
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744

Query: 319 PVKNLNGTGP--VHPALAGMTGILLCAAGLPVCLTRAP---KPILHPPPVSKSDVKPVPG 373
           P  + + T P  V P LA     L      P  L  +P    P   PP ++   ++ +P 
Sbjct: 745 PPMSPSATPPPRVPPLLAAPP--LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPS 802

Query: 374 VP 375
            P
Sbjct: 803 PP 804



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 43/135 (31%), Positives = 56/135 (41%), Gaps = 29/135 (21%)

Query: 218 ILASQRRKAPPAPPLPPP------PPPGGPPGALAV-------RPSATFTGAALWAAPAA 264
           +LA+   + PP+PP   P      PPP  PP ALA         P A+F G A ++  A+
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPP-ALATPPLQALPSPPASFPGQAPFSPSAS 818

Query: 265 GPAEP--APPPGAPP--------RSPGAPGGARTPGQNNLNRPGPQRTTSVSA---RASI 311
            P  P   PPP APP          P  P             PGP   TSVS      ++
Sbjct: 819 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD--TSVSGPRLTLAL 876

Query: 312 PPGVPALPVKNLNGT 326
            PG P  P ++ + T
Sbjct: 877 APGPPPPPSRSPSST 891



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 56/184 (30%), Positives = 69/184 (37%), Gaps = 49/184 (26%)

Query: 225 KAPP---APPLP-PPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP---PGAPP 277
           +APP   APPL  PP PP  PP    + PSAT         P   P   APP   P +PP
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPP----MSPSAT-------PPPRVPPLLAAPPLQVPPSPP 773

Query: 278 RS----------PGAPGGARTPGQNNLNRP----------GPQRTTSVSARASIPPGVP- 316
            S          P AP    TP    L  P           P  +  +S  A+ PP  P 
Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833

Query: 317 --ALPVKNLNGTGPVHPALAG-----MTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVK 369
             A P+  +  + P  P L         G     +G  + L  AP P   PPP S+S   
Sbjct: 834 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP---PPPPSRSPSS 890

Query: 370 PVPG 373
            + G
Sbjct: 891 TLSG 894



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 51/172 (29%), Positives = 66/172 (38%), Gaps = 29/172 (16%)

Query: 219 LASQRRKAPPAPPLPPP------PPPGGPP----GALAVRPSATFTGAALWAAPAAGPAE 268
           LA+   + PP+PP  PP      PPP  PP      L V PS     A+L  +P A P  
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP---ASLPMSPLAKPPP 786

Query: 269 PAPPPGAPPRSPGAPGG-ARTPGQ-----------NNLNRPGPQRTTSVSARA----SIP 312
            APP  A P     P   A  PGQ           + L  P PQ    ++A        P
Sbjct: 787 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 846

Query: 313 PGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVS 364
           P  P L       T     +++G    L  A G P   +R+P   L  P ++
Sbjct: 847 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 59/208 (28%), Positives = 80/208 (38%), Gaps = 53/208 (25%)

Query: 212 RAASNAILASQRRKAP----PAPPLPPPPPPGGPPGALAVRPSATFTGAALWA------- 260
           +A + A   +   +AP    P PP  P PPP   P AL V  +A   G    A       
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 261 -------APAAGPAEPA----------PPPG-----APPRSPGAPGGARTPGQ-NNLNRP 297
                  AP AGP   A          PP       APP    +PG   +PG+ +   RP
Sbjct: 67  GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 298 GP--QRTTSVSARASIPPG----------VPALPVKNLNG--TGPVHPALAGMTGILLCA 343
           GP  Q+   +SA  ++  G          + A   ++ +G   G   PA+A  +     A
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR----A 182

Query: 344 AGLPVCLTRAPKPILHPPPVSKSDVKPV 371
           AG  V L R P P   P P ++   K V
Sbjct: 183 AGTEVGLPR-PAPSARPRPPTEGPRKSV 209



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 45/152 (29%), Positives = 53/152 (34%), Gaps = 17/152 (11%)

Query: 230 PPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAP-GGART 288
           PP P P P   PP  L   P  T +  A             PPP APP     P  G  +
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIA------------TPPPQAPPALASPPLQGLPS 608

Query: 289 PGQNNLNRPGPQRTTSVS-ARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLP 347
           P  + L  P PQ    ++      PP  PA P  +   T P   A   +   LL A   P
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT-PSPQAPNALAVHLLQAPFSP 667

Query: 348 VCLTRAPKPILHP--PPVSKSDVKPVPGVPGV 377
                   P   P  PPVS S   P    P +
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 52/215 (24%), Positives = 70/215 (32%), Gaps = 28/215 (13%)

Query: 185 PKSQSWPVGA---SSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG- 240
           PK  +   GA   +SG         +   +RAA   +     R AP A P PP   P   
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKS 208

Query: 241 -----------PPGALAVRPSA-------TFTGAALWAAPAAGPAEPAPPPGAPPRSPGA 282
                      P  A   RPSA            +  A P + PA   P     PR+P  
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268

Query: 283 PGGARTPGQNNLNRP--GPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGIL 340
           P   +  G   L  P   P R  +  A   +     A P  +     PV P     T + 
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP 328

Query: 341 LCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
                 P   T  P P+  P P +   ++ +P  P
Sbjct: 329 ATLPPSPPLAT--PLPLAPPSPSAPPSLQTLPSPP 361



 Score = 37.7 bits (86), Expect = 0.032
 Identities = 47/162 (29%), Positives = 59/162 (36%), Gaps = 28/162 (17%)

Query: 220 ASQRRKAPPAPPLPPPPPPGGP---PGALAVRPSATFTGAALWAAPAA-----GPAEPA- 270
           AS+     P+P     P  GG    P + ++  SAT   +   + P+A      PA P+ 
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271

Query: 271 ----------PPPGAPPRSPGAPGGARTP-GQNNLNRPGPQRTTSVSARASIPPGVPALP 319
                     PP   PPR   AP  A  P   + L  P P  T    AR   PP   A P
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAP--ALGPLSSSPLATPSPSGT---KARPVPPPDNAATP 326

Query: 320 VKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPP 361
              L  T P  P LA    +   +   P  L   P P   PP
Sbjct: 327 ---LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPP 365



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 9/84 (10%)

Query: 220  ASQRRKAPP-----APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPG 274
            A  R  APP     AP  P P PP   PG+     +   T     A PA G  +P P PG
Sbjct: 939  AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 998

Query: 275  APPRSPGAPGGA----RTPGQNNL 294
                   A  GA    R+P Q  L
Sbjct: 999  TSGGKAAAGAGAGASSRSPKQARL 1022



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 39/159 (24%), Positives = 50/159 (31%), Gaps = 34/159 (21%)

Query: 194 ASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG-----PPGALAVR 248
           A  G      + L  ++T  +S A      R  P AP  P  P P G     PP     R
Sbjct: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 249 PSATFTGAALWAAPAAGP------AEPAPPPG----------------------APPRSP 280
             A      L ++P A P      A P PPP                       APP SP
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP-SP 348

Query: 281 GAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALP 319
            AP   +T        P     +  +     PP +  +P
Sbjct: 349 SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387



 Score = 31.2 bits (69), Expect = 3.0
 Identities = 32/102 (31%), Positives = 41/102 (40%), Gaps = 17/102 (16%)

Query: 225 KAPPAPP-----------LPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPP 273
           KA P PP           LPP PP   P       PSA  +   L + PA  P++  P  
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 274 GAPPRSPGAPGGART--PGQ--NNLNRPGPQRTTSVSARASI 311
             PP    AP   +T  P Q  ++L  P  Q   S  A +S+
Sbjct: 373 TTPPMQ--APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 35/97 (36%), Positives = 41/97 (42%), Gaps = 13/97 (13%)

Query: 226 APPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAP------PPGAPPRS 279
           A   PP P PPPP  P  A A   +     AA  A P+ GPA+P P      P  APP +
Sbjct: 124 AAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPA 183

Query: 280 PGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVP 316
           P AP     P        GP+R    +  A  PP  P
Sbjct: 184 PAAPPAVAPPA-------GPRRAPPPAVAAREPPLPP 213



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 49/144 (34%), Positives = 56/144 (38%), Gaps = 31/144 (21%)

Query: 224 RKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP----PGAPPRS 279
           R  PP     PP PP  P GA A         AA  AAP   PA P PP      AP R+
Sbjct: 98  RVQPPRRGATPPAPPRAPRGAPA---------AAAAAAPPPTPAPPPPPAPVAAAAPARA 148

Query: 280 PGAPGGART-PGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTG 338
           P A   A T P      +PGP+     +A  + PP  PA P           PA+A   G
Sbjct: 149 PRAAAAAATAPPSPGPAQPGPR--AQRAAPLAAPPPAPAAP-----------PAVAPPAG 195

Query: 339 ILLCAAGLPVCLTRAPKPILHPPP 362
                   P     A +P L PPP
Sbjct: 196 ----PRRAPPPAVAAREPPLPPPP 215



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 3/101 (2%)

Query: 220 ASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRS 279
           A+    APP+P    P P       LA  P A     A+  AP AGP   APPP    R 
Sbjct: 152 AAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAV--APPAGPRR-APPPAVAARE 208

Query: 280 PGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPV 320
           P  P   + P      +P P +        ++  G  A PV
Sbjct: 209 PPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPV 249



 Score = 33.1 bits (74), Expect = 0.78
 Identities = 33/136 (24%), Positives = 44/136 (32%), Gaps = 10/136 (7%)

Query: 245 LAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSP-GAPGGARTPGQNNLNRPGPQRTT 303
           ++ + S ++  AA    P  G   P     APPR+P GAP  A          P P    
Sbjct: 85  VSYKGSISYRNAARVQPPRRGATPP-----APPRAPRGAPAAAAAAAPPPTPAPPPPPAP 139

Query: 304 SVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLC----AAGLPVCLTRAPKPILH 359
             +A  +  P   A         GP  P         L     A   P  +     P   
Sbjct: 140 VAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRA 199

Query: 360 PPPVSKSDVKPVPGVP 375
           PPP   +   P+P  P
Sbjct: 200 PPPAVAAREPPLPPPP 215



 Score = 30.4 bits (67), Expect = 5.1
 Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 3/54 (5%)

Query: 236 PPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTP 289
           P PG   G   V   A        A+ A GP  P+P P  PP  P  PG   TP
Sbjct: 395 PAPGS--GTRQVFSMAAMNKEGGTASVATGPDSPSPVP-LPPGKPALPGADGTP 445


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 53/173 (30%), Positives = 61/173 (35%), Gaps = 61/173 (35%)

Query: 217 AILASQRRKAPPAPPL----PPPPPP----GGPPGALAVRPSATFTGAALWAAPAAGPAE 268
           A+    RR+APP PP     PPPPPP     GPP                   PA G   
Sbjct: 267 AVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP-----------------PPPARGRGA 309

Query: 269 PAPPP------GAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKN 322
           P PPP        PP  P  P  A  P       P P R          PP  PALP   
Sbjct: 310 PPPPPSRAPTAAPPPPPPSRPSVAVPP-------PPPNR--------MYPPPPPALPSSA 354

Query: 323 LNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
            +G  P  P++ G+  +             AP P   PPP       P PG+P
Sbjct: 355 PSGPPPPPPSVLGVGPV-------------APPP--PPPPPPPPGPPPPPGLP 392



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 30/97 (30%), Positives = 37/97 (38%), Gaps = 14/97 (14%)

Query: 224 RKAPPAPP------LPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPG--- 274
           R APP PP       PPPPPP  P  A+   P          A P++ P+ P PPP    
Sbjct: 307 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVL 366

Query: 275 -----APPRSPGAPGGARTPGQNNLNRPGPQRTTSVS 306
                APP  P  P     P    L   G  +  + +
Sbjct: 367 GVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTA 403



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 15/32 (46%), Positives = 16/32 (50%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAAL 258
           PP PP  PPPPPG P       P+     AAL
Sbjct: 378 PPPPPPGPPPPPGLPSDGDHQVPTTAGNKAAL 409


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 3/111 (2%)

Query: 226 APPAPPLPPPPPPGGPPGALAVRPSATFTGAAL--WAAPAAGPAEPAPPPGAPPRS-PGA 282
           APP P  PPPPPP  PP    + P++  +  A+    AP   P  P P P  PP   PG 
Sbjct: 216 APPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGL 275

Query: 283 PGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPAL 333
                +P Q+    P P       A  S    +PA P+  +N +    P L
Sbjct: 276 KAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPL 326



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 45/159 (28%), Positives = 54/159 (33%), Gaps = 31/159 (19%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA 286
           PP PPLPPP P   P     V P    T   L       P  P PPP  PP +P      
Sbjct: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTP-----P 235

Query: 287 RTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNG--TGPVHPALAGMTGILLCAA 344
             P  + L+    +   +      IPP +P LP     G    P  PA            
Sbjct: 236 PLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA------------ 283

Query: 345 GLPVCLTRAPKPILHPPPV------SKSDVKPVPGVPGV 377
                   A +P   PPP+      S     P P +PGV
Sbjct: 284 ------QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGV 316



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 21/53 (39%), Positives = 21/53 (39%), Gaps = 26/53 (49%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRS 279
           PP PPLPPPPPP G P                          P PPP APP S
Sbjct: 6   PPPPPLPPPPPPLGAP--------------------------PPPPPSAPPVS 32



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 41/155 (26%), Positives = 59/155 (38%), Gaps = 10/155 (6%)

Query: 228 PAPPLPPPPPPGG--PPGALAVRPSATFTGAALWAAPAAGPAEPAPP---PGAPPRSPGA 282
           P+P LP     G   PP +  +  ++   GAA  A P      P PP   P  PP  P  
Sbjct: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPL 190

Query: 283 PGGA--RTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGIL 340
           P  +  +TP    ++ PGP    ++   A   P  P  P      T P  P  + ++   
Sbjct: 191 PSSSPIKTP---LVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKA 247

Query: 341 LCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
           +     P+ L   P P+   PP     +K  P  P
Sbjct: 248 VKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASP 282



 Score = 36.6 bits (83), Expect = 0.071
 Identities = 38/102 (37%), Positives = 46/102 (45%), Gaps = 25/102 (24%)

Query: 230 PPLPPP---PPPGGPPGALAVRPSATFTGAALWAAPAAGPAE-PAPPPGAPPRSPGAPGG 285
           PP+PPP    PP G PG L   P          A+PA    E PAPPP  PP +  +P  
Sbjct: 258 PPIPPPLPLLPPCGYPG-LKAEP----------ASPAQDAQEPPAPPPPLPPYASCSPRA 306

Query: 286 A----RTPGQNNLNR-PGPQRTTSVSARASIPP---GVPALP 319
           +      PG N+ +  P P    S S +A  PP   G  ALP
Sbjct: 307 SLPAPPLPGVNSSSETPPPLPPKSPSFQA--PPQKAGAQALP 346



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 30/104 (28%), Positives = 38/104 (36%), Gaps = 12/104 (11%)

Query: 221 SQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEP---APPPGAP- 276
           +Q  + PPAPP P PP     P A    P      ++    P   P  P   APP  A  
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGA 342

Query: 277 ---PRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPA 317
              P  P  PG      +    RPG     +   + + PP  PA
Sbjct: 343 QALPAPPAPPGSQPFLQKKRHGRPG-----AGGGKLNPPPAPPA 381



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 26/80 (32%), Positives = 28/80 (35%), Gaps = 23/80 (28%)

Query: 224 RKAPPAPPLP---------PPPPPGGP--------------PGALAVRPSATFTGAALWA 260
           R + PAPPLP         PP PP  P              P   A   S  F       
Sbjct: 305 RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHG 364

Query: 261 APAAGPAEPAPPPGAPPRSP 280
            P AG  +  PPP  P RSP
Sbjct: 365 RPGAGGGKLNPPPAPPARSP 384



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 24/77 (31%), Positives = 29/77 (37%), Gaps = 8/77 (10%)

Query: 225 KAPPAPPLP----PPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSP 280
           KA PA P      PP PP   P   +  P A+     L   P    +   PPP  PP+SP
Sbjct: 276 KAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPL---PGVNSSSETPPP-LPPKSP 331

Query: 281 GAPGGARTPGQNNLNRP 297
                 +  G   L  P
Sbjct: 332 SFQAPPQKAGAQALPAP 348


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 53/165 (32%), Positives = 59/165 (35%), Gaps = 26/165 (15%)

Query: 227 PPAPPLPP-PPPPG--------GPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPP 277
           PP PP PP PPPPG        GPP      P         +  P  GP  P PPP  P 
Sbjct: 243 PPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPG 302

Query: 278 RSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVP--ALPVKNLNGTGPVHPALAG 335
             P  P G   P Q     PGP        R   P G P    P  +L G  P  P  A 
Sbjct: 303 YGP--PPGPPPPQQGPPPPPGP-----FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355

Query: 336 MTGILL----CAAGLPVCLTRAP---KPILHPPPVSKSDVKPVPG 373
                       +G+P   +R P    P   PPP  + D  P PG
Sbjct: 356 HVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP-PG 399



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 28/95 (29%), Positives = 31/95 (32%), Gaps = 14/95 (14%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA 286
           P     P P  PGGPP          F        P  GP  P  PPG PP     P   
Sbjct: 212 PGGDRFPGPAGPGGPP--------PPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPL 263

Query: 287 RTPGQNNLNRPGPQ-----RTTSVSARASIPPGVP 316
             P  N  +RP P      +         +PPG P
Sbjct: 264 AGP-PNRGDRPPPPVLFPGQPFGQPPLGPLPPGPP 297


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 60/168 (35%), Positives = 67/168 (39%), Gaps = 22/168 (13%)

Query: 227  PPAPPLP----PPPPPGGPPGALAVRPSATFTGAALWAAP---AAGPAEPAPPPGA---- 275
            PP PPLP    PPPPP   PGA  + P     GA +   P    AG   P P PGA    
Sbjct: 1020 PPPPPLPGAGIPPPPP--LPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1076

Query: 276  PPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIP-PGVPALPVKNLNGTG-PVHPAL 333
            PP  PGA G    P       P P     V      P PG    P   L G G P  P L
Sbjct: 1077 PPPLPGA-GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1135

Query: 334  AGMTGIL----LCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
             G  GI     L   G+P         I  PPP+  + + P P +PGV
Sbjct: 1136 PG-AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1182



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 57/167 (34%), Positives = 64/167 (38%), Gaps = 20/167 (11%)

Query: 227  PPAPPLP----PPPPPGGPPGALAVRPSATFTGAALWAAP---AAGPAEPAPPPGA---- 275
            PP PPLP    PPPPP   PGA  + P     GA +   P    AG   P P PGA    
Sbjct: 1031 PPPPPLPGAGIPPPPP--LPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087

Query: 276  PPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIP-PGVPALPVKNLNGTGPVHPALA 334
            PP  PGA G    P    +  P P            P PG    P   L G G   P   
Sbjct: 1088 PPPLPGA-GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146

Query: 335  GMTGIL----LCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
               GI     L  AG+P         I  PPP+    + P P +PGV
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGV 1193



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 60/175 (34%), Positives = 71/175 (40%), Gaps = 36/175 (20%)

Query: 227  PPAPPLP----PPPPP----GGP-----PGALAVRPSATFTGAALWAAP---AAGPAEPA 270
            PP PPLP    PPPPP    G P     PGA  + P     GA +   P    AG   P 
Sbjct: 943  PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001

Query: 271  PPPGA----PPRSPGA--PGGARTPGQNNLNRPGPQRTTSVSARASIP-PGVPALPVKNL 323
            P PGA    PP  PGA  P     PG   +  P P     +     +P  G+P  P   L
Sbjct: 1002 PLPGAGIPPPPPLPGAGIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIP--PPPPL 1058

Query: 324  NGTG-PVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
             G G P  P L G        AG+P         I  PPP+  + + P P +PGV
Sbjct: 1059 PGAGIPPPPPLPG--------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1105



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 54/164 (32%), Positives = 64/164 (39%), Gaps = 27/164 (16%)

Query: 227  PPAPPLP----PPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPP-----GAPP 277
            PP PPLP    PPPPP   PGA  + P     GA +   P    A   PPP     G PP
Sbjct: 1009 PPPPPLPGAGIPPPPP--LPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1065

Query: 278  RSP----GAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTG-PVHPA 332
              P    G P     PG   +  P P     +     + PGV   P   L G G P  P 
Sbjct: 1066 PPPLPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPL-PGVGIPPPPPLPGAGIPPPPP 1123

Query: 333  LAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPG 376
            L G        AG+P         I  PPP+ +  + P P +PG
Sbjct: 1124 LPG--------AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG 1159



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 55/164 (33%), Positives = 64/164 (39%), Gaps = 25/164 (15%)

Query: 227  PPAPPLP----PPPPPGGPPGALAVRPSATFTGAALWAAP---AAGPAEPAPPPGA---- 275
            PP PPLP    PPPPP   PGA  + P     GA +   P     G   P P PGA    
Sbjct: 1064 PPPPPLPGAGIPPPPP--LPGA-GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120

Query: 276  PPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIP-PGVPALPVKNLNGTG-PVHPAL 333
            PP  PGA G    P       P P     V      P PG    P   L G G P  P L
Sbjct: 1121 PPPLPGA-GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179

Query: 334  AGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGV 377
             G+        G+P         I  PPP+  + + P P +PG+
Sbjct: 1180 PGV--------GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGM 1215



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 57/167 (34%), Positives = 63/167 (37%), Gaps = 28/167 (16%)

Query: 226  APPAPP-------LPPPPPPGGPPGALAVRPSATFTGAA---LWAAPAAGPAEPAPPPGA 275
            A P PP       LPPPPPP   PGA  + P     GA    L   P AG   P P PGA
Sbjct: 895  AIPQPPPLQGTEMLPPPPPP--LPGA-GIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA 951

Query: 276  ----PPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIP-PGVPALPVKNLNGTG-PV 329
                PP  PGA G    P       P P            P PG    P   L G G P 
Sbjct: 952  AIPPPPPLPGA-GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1010

Query: 330  HPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPG 376
             P L G        AG+P         I  PPP+  + + P P +PG
Sbjct: 1011 PPPLPG--------AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 56/175 (32%), Positives = 65/175 (37%), Gaps = 42/175 (24%)

Query: 227  PPAPPLP----PPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPP-----GAPP 277
            PP PPLP    PPPPP   PG + + P     GA +   P    A   PPP     G PP
Sbjct: 1086 PPPPPLPGAGIPPPPP--LPG-VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1142

Query: 278  RSP----GAPGGARTPGQNNLNRPGPQRTTSVSARASIP----------PGVPALPVKNL 323
              P    G P     PG   +  P P     +     +P          PGV   P   L
Sbjct: 1143 PPPLPRVGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPL 1201

Query: 324  NGTG-PVHPALAGMTGILLCAAGLPVCLTRAPKPILHPP--PVSKSDVKPVPGVP 375
             G G P  P L GM        G+P     AP P L PP   +    + PV G P
Sbjct: 1202 PGAGIPPPPPLPGM--------GIP----PAPAPPLPPPGTGIPPPPLLPVSGPP 1244



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 61/224 (27%), Positives = 85/224 (37%), Gaps = 50/224 (22%)

Query: 181 VGSIPKSQSWPVGASSG-QPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPP---- 235
           V  +P     P GA SG Q   C +  L+ S R  S  + + Q  ++   PP PP     
Sbjct: 760 VDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWS 819

Query: 236 ----PPPGGPPGALAVR--------PSATFTGAALWAAPAAGPA--EPAPPPG---APPR 278
                P   PP +++           S+ F  +    +P   P     +  PG    PP 
Sbjct: 820 AGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPP 879

Query: 279 SPGAPG-GARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTG-PVHPALAGM 336
            P  PG    T     + +P P + T +     +PP  P LP     G G P  P L G 
Sbjct: 880 PPPLPGMTVPTLPSTAIPQPPPLQGTEM-----LPPPPPPLP-----GAGIPPPPPLPG- 928

Query: 337 TGIL----LCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPG 376
            GIL    L  AG+P            PPP+  + + P P +PG
Sbjct: 929 AGILPLPPLPGAGIP-----------PPPPLPGAAIPPPPPLPG 961



 Score = 33.9 bits (76), Expect = 0.46
 Identities = 28/94 (29%), Positives = 35/94 (37%), Gaps = 15/94 (15%)

Query: 227  PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGA---PPRSPGAP 283
            PP P +  PPPP  P     + P     G  +  A    PA P PPPG    PP      
Sbjct: 1188 PPLPGVGIPPPP--PLPGAGIPPPPPLPGMGIPPA----PAPPLPPPGTGIPPPPLLPVS 1241

Query: 284  GGARTPGQNNLNRPGPQRTTSVSARASIPPGVPA 317
            G    P   +   P PQ          +PP +P+
Sbjct: 1242 GPPLLPQVGSSTLPTPQ------VCGFLPPPLPS 1269



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 34/113 (30%), Positives = 43/113 (38%), Gaps = 25/113 (22%)

Query: 226 APPAPPLPPPPPPGGP----PGALAVRPSATFT-GAALWAAPAAGPAEPAPPPGAPPRSP 280
           A P  P  PP P G P    P   A +P+A  +  +  +  P AGP E A   GAP R  
Sbjct: 285 AEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEA--AGAPVRGA 342

Query: 281 G-------------APGGARTPGQN---NLNRPGPQRTTSVSARASIPPGVPA 317
           G             AP G  +PG+     +    PQR        +  P  PA
Sbjct: 343 GDTDEEGEEDAFEDAPRG--SPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPA 393


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 55/164 (33%), Positives = 66/164 (40%), Gaps = 42/164 (25%)

Query: 227 PPAPPLP---PPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAP 283
           PP PPLP   PPPPPGG P               L   P  GPA P+ PPG P   P AP
Sbjct: 242 PPRPPLPESLPPPPPGGLP---------------LPPMPPTGPA-PSGPPGPPQLPPPAP 285

Query: 284 GGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGP-VHPALAGM----TG 338
           G         ++ P P      S      PGV   P   ++   P VHP  +G+     G
Sbjct: 286 G---------VHPPAPVVHPPASGVHPPAPGVHP-PAPGVHPPAPGVHPPTSGVHPPAPG 335

Query: 339 ILLCAAGL--PVCLTRAPKPILHPP-----PVSKSDVKP-VPGV 374
           +   A G+  P      P P +HPP     P   + V P  PGV
Sbjct: 336 VHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGV 379



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 55/173 (31%), Positives = 67/173 (38%), Gaps = 39/173 (22%)

Query: 223 RRKAPPAPPLPPPPPPG--GPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSP 280
           + + PPAPP  P  PPG   PP  L            L   P    + P PPPG  P  P
Sbjct: 213 KMEKPPAPPSLPAGPPGVKRPPPPLM---------NGLPPRPPLPESLPPPPPGGLPLPP 263

Query: 281 GAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGV-PALPVKNLNGTGPVHPALAGM--- 336
             P G    G      PGP +    +      PGV P  PV +   +G VHP   G+   
Sbjct: 264 MPPTGPAPSGP-----PGPPQLPPPA------PGVHPPAPVVHPPASG-VHPPAPGVHPP 311

Query: 337 -TGILLCAAGL--PVCLTRAPKPILHPP-----PVSKSDVKPVPGV----PGV 377
             G+   A G+  P      P P +HPP     P +     P PGV    PGV
Sbjct: 312 APGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV 364



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 33/96 (34%), Positives = 40/96 (41%), Gaps = 5/96 (5%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGA 286
           PPAP + PP P   PP +  V P A        AAPA  P  P   P AP   P APG  
Sbjct: 352 PPAPGVHPPAPGVHPPPSAGVHPQAPGVHP---AAPAVHPQAPGVHPPAPGMHPQAPGVH 408

Query: 287 RTPGQNNLNRPG--PQRTTSVSARASIPPGVPALPV 320
             P   + + PG  PQ      +   + P  P  P+
Sbjct: 409 PQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPM 444



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 46/162 (28%), Positives = 55/162 (33%), Gaps = 16/162 (9%)

Query: 227 PPAPPLP--PPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGA-- 282
           PP  P P  PP PP  PP A  V P A              P    P PG  P +PG   
Sbjct: 265 PPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHP 324

Query: 283 PGGARTPGQNNLNRPGPQRTTSVSARASIPPGV-PALPVKNLNGTGPVHPALAGM----T 337
           P     P    ++ P P             PGV P  P  +   +  VHP   G+     
Sbjct: 325 PTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAP 384

Query: 338 GILLCAAGLPVCLTRAPKPILHP--PPVSKSDVKPVPGVPGV 377
            +   A G+       P P +HP  P V        P  PGV
Sbjct: 385 AVHPQAPGV-----HPPAPGMHPQAPGVHPQPPGVHPSAPGV 421



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 24/73 (32%), Positives = 26/73 (35%), Gaps = 9/73 (12%)

Query: 227 PPAPPLPP------PPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSP 280
           PPAP + P      P PPG  P A  V P       +    P   P  P PP   PP   
Sbjct: 395 PPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPS---NPGVHPPTPMPPMLRPPLPS 451

Query: 281 GAPGGARTPGQNN 293
             PG    P   N
Sbjct: 452 EGPGNIPPPPPTN 464


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 32/97 (32%), Positives = 42/97 (43%), Gaps = 11/97 (11%)

Query: 227  PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAP-----PPGAPPRSPG 281
            PP  P PPPPP    P    V+  A     +   +PA  PA   P     PPG PP    
Sbjct: 1268 PPVSPKPPPPPTAPKP----VKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGA 1323

Query: 282  APGGARTPGQNNLNRPG--PQRTTSVSARASIPPGVP 316
            +P    +PG   L+ P   P+   + +A A+ PP  P
Sbjct: 1324 SPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPP 1360



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 55/174 (31%), Positives = 69/174 (39%), Gaps = 52/174 (29%)

Query: 222  QRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAE--PAPPPGAPPRS 279
            +R KA      P PPPP      L+V  + T T     A+  AGP E  P PPP  PP +
Sbjct: 1150 RRPKAKEREAGPEPPPP------LSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPT 1203

Query: 280  --------PGAPGGARTPGQNN------LNRPGPQ---RTTSVSARASIP-PGVPALPVK 321
                    P   G AR P +        L +P P+     T  S +  +P PG P   VK
Sbjct: 1204 DLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSP--EVK 1261

Query: 322  NLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
              +GT P                  PV    +PKP   PPP +   VK V G+P
Sbjct: 1262 RAHGTPP------------------PV----SPKP--PPPPTAPKPVKAVAGLP 1291



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 49/156 (31%), Positives = 60/156 (38%), Gaps = 16/156 (10%)

Query: 230  PPLPPPPPPGGPP--GALAVRPSATFTGAALWAAPAAGPAEPAPPPGAP-PRSPGAPGGA 286
            P LPPPPPP  PP      + P     G A    PA  P  P P    P P+  G+P   
Sbjct: 1189 PELPPPPPPAEPPPTDLAHLPPLPPPEGEA--RKPAKPPVSPKPVLTQPVPKLQGSP--- 1243

Query: 287  RTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGL 346
             TP    +  PGP  +  V      PP V   P        PV  A+AG+       +  
Sbjct: 1244 -TPTSKKVPLPGP-GSPEVKRAHGTPPPVSPKPPPPPTAPKPV-KAVAGLPSGSAGPSPA 1300

Query: 347  PVCLTRAP----KPILHPPPVSKSDVK-PVPGVPGV 377
            P    + P    KP   PP +  S  K P PG P +
Sbjct: 1301 PSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPAL 1336



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 37/126 (29%), Positives = 49/126 (38%), Gaps = 21/126 (16%)

Query: 229  APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP---PGAPPR------- 278
            A P P P P   PP ALA  P    T  +L A+PA  P+  AP    P  PPR       
Sbjct: 1295 AGPSPAPSPARQPPAALAKPPG---TPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAA 1351

Query: 279  ---SPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAG 335
               +P AP    +PG +       Q+    SA  +         ++  +  GP   A   
Sbjct: 1352 AAAAPPAPPEGASPGDS-----ARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEK 1406

Query: 336  MTGILL 341
             TG +L
Sbjct: 1407 STGSIL 1412



 Score = 37.4 bits (85), Expect = 0.041
 Identities = 46/178 (25%), Positives = 61/178 (34%), Gaps = 24/178 (13%)

Query: 223 RRKAPPA---PPLPPPPPPGGPPGALAVRPSATFTGAAL---WAAPAAGPAEPAPPPGAP 276
           RRKAP +     +  PPPP   P         TF  + L     A   GPAE  P    P
Sbjct: 619 RRKAPQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKP 678

Query: 277 PRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPA--LA 334
             S   P   R   + + +  G  R  S S              + L G GP  P+  ++
Sbjct: 679 --SSHLPPTPRATTRQDSSLGGRARHMSSS--------------QELLGDGPPGPSSPMS 722

Query: 335 GMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNP 392
                LL     P    R  +P  H   + ++ V PVPG P         H    + P
Sbjct: 723 RSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTP 780



 Score = 33.5 bits (75), Expect = 0.60
 Identities = 28/62 (45%), Positives = 30/62 (48%), Gaps = 10/62 (16%)

Query: 225  KAPPAPPLPPP--PP-----PGGP--PGALAVRPSATFTGAALWAAPAAGPAEPAPPPGA 275
            + PPA    PP  PP     P  P  PGA A+   A    AA  AA AA  A PAPP GA
Sbjct: 1305 RQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAA-AAAAAAAAPPAPPEGA 1363

Query: 276  PP 277
             P
Sbjct: 1364 SP 1365



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 13/108 (12%)

Query: 300  QRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILH 359
            +R      R + P   P L V + NGTG V    A         AG P      P P   
Sbjct: 1149 KRRPKAKEREAGPEPPPPLSVYH-NGTGTVRRRPASEQ------AGPPEL--PPPPPPAE 1199

Query: 360  PPPVSKSDVKPVPGVPGVCRKTKKKHLKKSKNPEDVVRRYMQKVKNPP 407
            PPP   + + P+P   G  RK  K  +    +P+ V+ + + K++  P
Sbjct: 1200 PPPTDLAHLPPLPPPEGEARKPAKPPV----SPKPVLTQPVPKLQGSP 1243


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 53/190 (27%), Positives = 69/190 (36%), Gaps = 21/190 (11%)

Query: 191 PVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPS 250
           P+ A    P S     L   +  A NA+     +     PP PP   P  PP +  V PS
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463

Query: 251 ATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTP-----GQNNLNRPGPQRTTSV 305
           AT    A  +  A     P  PP +PP SP A    + P         L +P PQ   + 
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ---AP 520

Query: 306 SARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSK 365
            A A+ P      P  +  G  P  P           +A LP+     P P    PPV  
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSP-----------SASLPMSPLATPPP--QAPPVLA 567

Query: 366 SDVKPVPGVP 375
           + +  VP  P
Sbjct: 568 APLLQVPPSP 577



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 49/159 (30%), Positives = 60/159 (37%), Gaps = 23/159 (14%)

Query: 219 LASQRRKAPPAPPLP----PPPPPGGPPGALAVRPSATFTGAA---LWAAPAAGPAEPAP 271
           LA+   +APPA  LP    PP PP  PP +    PS     A    L  AP + P  P+P
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSP 446

Query: 272 P---PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGP 328
           P   P +PP SP     A  P Q   +   P           +PP  PA P  + + T P
Sbjct: 447 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPP--------LQVPPSPPASPPMSPSATPP 498

Query: 329 VH---PALAGMTGILLCAAGLPVCLTRAPKPILHPPPVS 364
                P  A    +       P  L   P   L  PP S
Sbjct: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 537



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 51/205 (24%), Positives = 77/205 (37%), Gaps = 19/205 (9%)

Query: 219 LASQRRKAPPAPPLPP-----PPPPGGPPGALAV---RPSATFTGAALWA---APAAGPA 267
           LA+    APP+P  PP     P PP  PP         P+   T + L +   +P A P 
Sbjct: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393

Query: 268 EPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVS-----ARASIPPGVPALPVKN 322
             APP  A P     P    +P  + L  P PQ   +++     A  S PP  P     +
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453

Query: 323 LNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVPGVCRKTK 382
              + PV P+    +      A  P+ +  +P      PP+S S   P    P +     
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA---SPPMSPSATPPPQAPPPLAAPPL 510

Query: 383 KKHLKKSKNPEDVVRRYMQKVKNPP 407
           +      + P  +    +Q + +PP
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPP 535



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 42/125 (33%), Positives = 51/125 (40%), Gaps = 19/125 (15%)

Query: 213 AASNAILASQRRKAPPAPPLPP----PPPPGGPPGALAVRPSATFTGAALWAAPAAGPAE 268
           AA    LA    +APPA   PP    P PP   PG     PSA+   + L   P   P  
Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565

Query: 269 PAPP----PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSA---RASIPPGVPALPVK 321
            A P    P +PP SP      R P       PGP   TSVS      ++ PG P  P +
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPP------TPGPD--TSVSGPRLTLALAPGPPPPPSR 617

Query: 322 NLNGT 326
           + + T
Sbjct: 618 SPSST 622



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 44/160 (27%), Positives = 62/160 (38%), Gaps = 18/160 (11%)

Query: 219 LASQRRKAPPAPPLPPP------PPPGGPPGALAVRPSATFTGAALWAAPAAGP----AE 268
           LA+   + PP+PP  PP      PPP  PP   A  P          A PA       A 
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA--PPLQLAKPPPQAPPALATPPLQAL 531

Query: 269 PAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARA----SIPPGVPALPVKNLN 324
           P+PP   P ++P +P  +     + L  P PQ    ++A        PP  P L      
Sbjct: 532 PSPPASFPGQAPFSPSASLP--MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 589

Query: 325 GTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVS 364
            T     +++G    L  A G P   +R+P   L  P ++
Sbjct: 590 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 629



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 59/208 (28%), Positives = 80/208 (38%), Gaps = 53/208 (25%)

Query: 212 RAASNAILASQRRKAP----PAPPLPPPPPPGGPPGALAVRPSATFTGAALWA------- 260
           +A + A   +   +AP    P PP  P PPP   P AL V  +A   G    A       
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 261 -------APAAGPAEPA----------PPPG-----APPRSPGAPGGARTPGQ-NNLNRP 297
                  AP AGP   A          PP       APP    +PG   +PG+ +   RP
Sbjct: 67  GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 298 GP--QRTTSVSARASIPPG----------VPALPVKNLNG--TGPVHPALAGMTGILLCA 343
           GP  Q+   +SA  ++  G          + A   ++ +G   G   PA+A  +     A
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR----A 182

Query: 344 AGLPVCLTRAPKPILHPPPVSKSDVKPV 371
           AG  V L R P P   P P ++   K V
Sbjct: 183 AGTEVGLPR-PAPSARPRPPTEGPRKSV 209



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 51/218 (23%), Positives = 71/218 (32%), Gaps = 37/218 (16%)

Query: 185 PKSQSWPVGA---SSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG- 240
           PK  +   GA   +SG         +   +RAA   +     R AP A P PP   P   
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKS 208

Query: 241 -----------PPGALAVRPSA-------TFTGAALWAAPAAGPAEPAPPPGAPPRSPGA 282
                      P  A   RPSA            +  A P + PA   P     PR+P  
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268

Query: 283 PGGARTPGQNNLNRP--GPQRTTSVSA---RASIPPGVPALPVKNLNGTGPVHPALAGMT 337
           P   +  G   L  P   P R  +  A    +S P   P+      +   P  PA    +
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSS 328

Query: 338 GILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
            +         C    P P+  P P +   ++ +P  P
Sbjct: 329 SL--------TCQLATPLPLAPPSPSAPPSLQTLPSPP 358



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 49/187 (26%), Positives = 64/187 (34%), Gaps = 33/187 (17%)

Query: 223 RRKAPPA------PPLPPPPPPGG-----PPGALAVRPSATFTGAALWAAPAAGPAEPAP 271
           R+ A PA       PL  P P        PP   A   S++ T       P A P+  AP
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348

Query: 272 --------PPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNL 323
                   PP  PP       G+ T    +   P P  +   +     PP + ALP    
Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL-ALPPLQA 407

Query: 324 NGTGPVHPALAGM-TGILLCAAGLPVCLTRAP------KPILHP------PPVSKSDVKP 370
             + P  P L+ + T        L V L +AP       P+  P      PPVS S   P
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467

Query: 371 VPGVPGV 377
               P +
Sbjct: 468 SQAPPSL 474



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 9/84 (10%)

Query: 220 ASQRRKAPP-----APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPG 274
           A  R  APP     AP  P P PP   PG+     +   T     A PA G  +P P PG
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729

Query: 275 APPRSPGAPGGA----RTPGQNNL 294
                  A  GA    R+P Q  L
Sbjct: 730 TSGGKAAAGAGAGASSRSPKQARL 753


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 53/190 (27%), Positives = 69/190 (36%), Gaps = 21/190 (11%)

Query: 191 PVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPS 250
           P+ A    P S     L   +  A NA+     +     PP PP   P  PP +  V PS
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424

Query: 251 ATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTP-----GQNNLNRPGPQRTTSV 305
           AT    A  +  A     P  PP +PP SP A    + P         L +P PQ   + 
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ---AP 481

Query: 306 SARASIPPGVPALPVKNLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSK 365
            A A+ P      P  +  G  P  P           +A LP+     P P    PPV  
Sbjct: 482 PALATPPLQALPSPPASFPGQAPFSP-----------SASLPMSPLATPPP--QAPPVLA 528

Query: 366 SDVKPVPGVP 375
           + +  VP  P
Sbjct: 529 APLLQVPPSP 538



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 58/199 (29%), Positives = 80/199 (40%), Gaps = 44/199 (22%)

Query: 212 RAASNAILASQRRKAP----PAPPLPPPPPPGGPPGALAVRPSATFTGAALWA------- 260
           +A + A   +   +AP    P PP  P PPP   P AL V  +A   G    A       
Sbjct: 7   KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 261 -------APAAGPAEPAPPPG------APPRSPGAPGGARTPGQ-NNLNRPGP--QRTTS 304
                  AP AGP   + PP       APP    +PG   +PG+ +   RPGP  Q+   
Sbjct: 67  GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126

Query: 305 VSARASIPPG----------VPALPVKNLNG--TGPVHPALAGMTGILLCAAGLPVCLTR 352
           +SA  ++  G          + A   ++ +G   G   PA+A  +     AAG  V L R
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR----AAGTEVGLPR 182

Query: 353 APKPILHPPPVSKSDVKPV 371
            P P   P P ++   K V
Sbjct: 183 -PAPSARPRPPTEGPRKSV 200



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 63/215 (29%), Positives = 79/215 (36%), Gaps = 31/215 (14%)

Query: 194 ASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPPPGG-----PPGALAVR 248
           A  G      + L  ++T  +S A      R  P AP  P  P P G     PP     R
Sbjct: 221 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 280

Query: 249 PSATFTGAALWAAPAAGPAEPAPP-PGAPPRSPGAPGGARTP---GQNNLNRPGPQRTTS 304
             A      L ++P A P+  APP P APP     P    TP      +L  P  Q T S
Sbjct: 281 KDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 340

Query: 305 ------VSARASIPPGVP---ALPVKNLNGTGPVHPALAGM-TGILLCAAGLPVCLTRAP 354
                 +S  A+ PP  P   ALP      + P  P L+ + T        L V L +AP
Sbjct: 341 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400

Query: 355 ------KPILHP------PPVSKSDVKPVPGVPGV 377
                  P+  P      PPVS S   P    P +
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 49/159 (30%), Positives = 60/159 (37%), Gaps = 23/159 (14%)

Query: 219 LASQRRKAPPAPPLP----PPPPPGGPPGALAVRPSATFTGAA---LWAAPAAGPAEPAP 271
           LA+   +APPA  LP    PP PP  PP +    PS     A    L  AP + P  P+P
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSP 407

Query: 272 P---PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGP 328
           P   P +PP SP     A  P Q   +   P           +PP  PA P  + + T P
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPP--------LQVPPSPPASPPMSPSATPP 459

Query: 329 VH---PALAGMTGILLCAAGLPVCLTRAPKPILHPPPVS 364
                P  A    +       P  L   P   L  PP S
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 498



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 42/125 (33%), Positives = 51/125 (40%), Gaps = 19/125 (15%)

Query: 213 AASNAILASQRRKAPPAPPLPP----PPPPGGPPGALAVRPSATFTGAALWAAPAAGPAE 268
           AA    LA    +APPA   PP    P PP   PG     PSA+   + L   P   P  
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526

Query: 269 PAPP----PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSA---RASIPPGVPALPVK 321
            A P    P +PP SP      R P       PGP   TSVS      ++ PG P  P +
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPRRPP------TPGPD--TSVSGPRLTLALAPGPPPPPSR 578

Query: 322 NLNGT 326
           + + T
Sbjct: 579 SPSST 583



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 44/160 (27%), Positives = 62/160 (38%), Gaps = 18/160 (11%)

Query: 219 LASQRRKAPPAPPLPPP------PPPGGPPGALAVRPSATFTGAALWAAPAAGP----AE 268
           LA+   + PP+PP  PP      PPP  PP   A  P          A PA       A 
Sbjct: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA--PPLQLAKPPPQAPPALATPPLQAL 492

Query: 269 PAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARA----SIPPGVPALPVKNLN 324
           P+PP   P ++P +P  +     + L  P PQ    ++A        PP  P L      
Sbjct: 493 PSPPASFPGQAPFSPSASLP--MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550

Query: 325 GTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVS 364
            T     +++G    L  A G P   +R+P   L  P ++
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 590



 Score = 35.0 bits (79), Expect = 0.21
 Identities = 29/84 (34%), Positives = 33/84 (39%), Gaps = 9/84 (10%)

Query: 220 ASQRRKAPP-----APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPG 274
           A  R  APP     AP  P P PP   PG+     +   T     A PA G  +P P PG
Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690

Query: 275 APPRSPGAPGGA----RTPGQNNL 294
                  A  GA    R+P Q  L
Sbjct: 691 TSGGKAAAGAGAGASSRSPKQARL 714



 Score = 31.6 bits (70), Expect = 2.3
 Identities = 32/114 (28%), Positives = 40/114 (35%), Gaps = 27/114 (23%)

Query: 236 PPPGGPPGALAVRPSATFTGAAL-WAAPAAGPAEPAP----------------PPGAPPR 278
           P PG P  A+A R  A  T   L   AP+A P  P                  P  A  R
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217

Query: 279 SPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPA 332
            P A GG + P   +L+       T +S+ A   P     P        P HP+
Sbjct: 218 RPSAGGGLQRPASRSLS----SSATPLSSPARSGPSARGTP------RAPAHPS 261


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 52/159 (32%), Positives = 62/159 (38%), Gaps = 13/159 (8%)

Query: 213 AASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP 272
           A S + L +     PP P  PPPPPP     A AV P      A L  AP  G   PAPP
Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPP----APLQIAP--GVLHPAPP 387

Query: 273 PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPA 332
           P APP    +P  AR           P     V      PP  P LP   +  + PV   
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIRPSSPV--- 443

Query: 333 LAGMTGILLCAAGLPVCLTRAPKP-ILHPPPVSKSDVKP 370
              +T +    +GL    + AP P +   PP   S V P
Sbjct: 444 --TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 47/150 (31%), Positives = 59/150 (39%), Gaps = 39/150 (26%)

Query: 229 APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPP----RSPGAPG 284
           +P  PPPPPP          PSA  T ++L A+  + P  P PPP  PP    ++P  P 
Sbjct: 321 SPTPPPPPPP---------LPSALST-SSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370

Query: 285 GAR----TPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGIL 340
                   PG   +  P P        + S PP   A PV     T PVHP   G     
Sbjct: 371 PPAPLQIAPG---VLHPAPPPIAPPLVQPS-PPVARAAPVCE---TVPVHPLPQGE---- 419

Query: 341 LCAAGLPVCLTRAPKPILHPPPVSKSDVKP 370
               GLP      P P   PPP+    ++P
Sbjct: 420 --VQGLP-----PPPP---PPPLPPPGIRP 439



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 16/72 (22%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAP---------AAGPAEPAPPPGAPP 277
           PP PP PP PPPG       +RPS+  T  AL   P         A GP  P  PP  P 
Sbjct: 424 PPPPPPPPLPPPG-------IRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476

Query: 278 RSPGAPGGARTP 289
           +   A    R P
Sbjct: 477 QVIPASEPKRHP 488



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 44/165 (26%), Positives = 54/165 (32%), Gaps = 22/165 (13%)

Query: 230 PPLPPPPPPGGPPGALAVRPSATFTGAALW----AAPAAGP----AEPAPPPGAPPRSPG 281
           P  PPPPPP    G     P+   +   L      +PA G       P PPP  PP    
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 282 APGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL 341
               +      +   P         A A   P VP  P       G +HPA   +   L+
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLV 394

Query: 342 -----CAAGLPVCLTRAPKPI-------LHPPPVSKSDVKPVPGV 374
                 A   PVC T    P+       L PPP       P PG+
Sbjct: 395 QPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP--PPPPLPPPGI 437



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 30/114 (26%), Positives = 35/114 (30%), Gaps = 23/114 (20%)

Query: 266 PAEPAPPPGAPPRSPGAPGGARTPGQNNL--NRPGPQRT--TSVSARASIPPGVPALPVK 321
           P EP PPP         P          L  NRP    T  T V    + PP  P LP  
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 322 NLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
                              L  + L   +T  P P + PPP   +     P VP
Sbjct: 335 -------------------LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 52/159 (32%), Positives = 62/159 (38%), Gaps = 13/159 (8%)

Query: 213 AASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP 272
           A S + L +     PP P  PPPPPP     A AV P      A L  AP  G   PAPP
Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPP----APLQIAP--GVLHPAPP 387

Query: 273 PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPA 332
           P APP    +P  AR           P     V      PP  P LP   +  + PV   
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIRPSSPV--- 443

Query: 333 LAGMTGILLCAAGLPVCLTRAPKP-ILHPPPVSKSDVKP 370
              +T +    +GL    + AP P +   PP   S V P
Sbjct: 444 --TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 47/150 (31%), Positives = 59/150 (39%), Gaps = 39/150 (26%)

Query: 229 APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPP----RSPGAPG 284
           +P  PPPPPP          PSA  T ++L A+  + P  P PPP  PP    ++P  P 
Sbjct: 321 SPTPPPPPPP---------LPSALST-SSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370

Query: 285 GAR----TPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGIL 340
                   PG   +  P P        + S PP   A PV     T PVHP   G     
Sbjct: 371 PPAPLQIAPG---VLHPAPPPIAPPLVQPS-PPVARAAPVCE---TVPVHPLPQGE---- 419

Query: 341 LCAAGLPVCLTRAPKPILHPPPVSKSDVKP 370
               GLP      P P   PPP+    ++P
Sbjct: 420 --VQGLP-----PPPP---PPPLPPPGIRP 439



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 16/72 (22%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAP---------AAGPAEPAPPPGAPP 277
           PP PP PP PPPG       +RPS+  T  AL   P         A GP  P  PP  P 
Sbjct: 424 PPPPPPPPLPPPG-------IRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476

Query: 278 RSPGAPGGARTP 289
           +   A    R P
Sbjct: 477 QVIPASEPKRHP 488



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 44/165 (26%), Positives = 54/165 (32%), Gaps = 22/165 (13%)

Query: 230 PPLPPPPPPGGPPGALAVRPSATFTGAALW----AAPAAGP----AEPAPPPGAPPRSPG 281
           P  PPPPPP    G     P+   +   L      +PA G       P PPP  PP    
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 282 APGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL 341
               +      +   P         A A   P VP  P       G +HPA   +   L+
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLV 394

Query: 342 -----CAAGLPVCLTRAPKPI-------LHPPPVSKSDVKPVPGV 374
                 A   PVC T    P+       L PPP       P PG+
Sbjct: 395 QPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP--PPPPLPPPGI 437



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 30/114 (26%), Positives = 35/114 (30%), Gaps = 23/114 (20%)

Query: 266 PAEPAPPPGAPPRSPGAPGGARTPGQNNL--NRPGPQRT--TSVSARASIPPGVPALPVK 321
           P EP PPP         P          L  NRP    T  T V    + PP  P LP  
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 322 NLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
                              L  + L   +T  P P + PPP   +     P VP
Sbjct: 335 -------------------LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 52/159 (32%), Positives = 62/159 (38%), Gaps = 13/159 (8%)

Query: 213 AASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP 272
           A S + L +     PP P  PPPPPP     A AV P      A L  AP  G   PAPP
Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPP----APLQIAP--GVLHPAPP 387

Query: 273 PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPA 332
           P APP    +P  AR           P     V      PP  P LP   +  + PV   
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIRPSSPV--- 443

Query: 333 LAGMTGILLCAAGLPVCLTRAPKP-ILHPPPVSKSDVKP 370
              +T +    +GL    + AP P +   PP   S V P
Sbjct: 444 --TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 47/150 (31%), Positives = 59/150 (39%), Gaps = 39/150 (26%)

Query: 229 APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPP----RSPGAPG 284
           +P  PPPPPP          PSA  T ++L A+  + P  P PPP  PP    ++P  P 
Sbjct: 321 SPTPPPPPPP---------LPSALST-SSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370

Query: 285 GAR----TPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGIL 340
                   PG   +  P P        + S PP   A PV     T PVHP   G     
Sbjct: 371 PPAPLQIAPG---VLHPAPPPIAPPLVQPS-PPVARAAPVCE---TVPVHPLPQGE---- 419

Query: 341 LCAAGLPVCLTRAPKPILHPPPVSKSDVKP 370
               GLP      P P   PPP+    ++P
Sbjct: 420 --VQGLP-----PPPP---PPPLPPPGIRP 439



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 16/72 (22%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAP---------AAGPAEPAPPPGAPP 277
           PP PP PP PPPG       +RPS+  T  AL   P         A GP  P  PP  P 
Sbjct: 424 PPPPPPPPLPPPG-------IRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476

Query: 278 RSPGAPGGARTP 289
           +   A    R P
Sbjct: 477 QVIPASEPKRHP 488



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 44/165 (26%), Positives = 54/165 (32%), Gaps = 22/165 (13%)

Query: 230 PPLPPPPPPGGPPGALAVRPSATFTGAALW----AAPAAGP----AEPAPPPGAPPRSPG 281
           P  PPPPPP    G     P+   +   L      +PA G       P PPP  PP    
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 282 APGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL 341
               +      +   P         A A   P VP  P       G +HPA   +   L+
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLV 394

Query: 342 -----CAAGLPVCLTRAPKPI-------LHPPPVSKSDVKPVPGV 374
                 A   PVC T    P+       L PPP       P PG+
Sbjct: 395 QPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP--PPPPLPPPGI 437



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 30/114 (26%), Positives = 35/114 (30%), Gaps = 23/114 (20%)

Query: 266 PAEPAPPPGAPPRSPGAPGGARTPGQNNL--NRPGPQRT--TSVSARASIPPGVPALPVK 321
           P EP PPP         P          L  NRP    T  T V    + PP  P LP  
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 322 NLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
                              L  + L   +T  P P + PPP   +     P VP
Sbjct: 335 -------------------LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 52/159 (32%), Positives = 62/159 (38%), Gaps = 13/159 (8%)

Query: 213 AASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP 272
           A S + L +     PP P  PPPPPP     A AV P      A L  AP  G   PAPP
Sbjct: 334 ALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPP----APLQIAP--GVLHPAPP 387

Query: 273 PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPA 332
           P APP    +P  AR           P     V      PP  P LP   +  + PV   
Sbjct: 388 PIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIRPSSPV--- 443

Query: 333 LAGMTGILLCAAGLPVCLTRAPKP-ILHPPPVSKSDVKP 370
              +T +    +GL    + AP P +   PP   S V P
Sbjct: 444 --TVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIP 480



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 47/150 (31%), Positives = 59/150 (39%), Gaps = 39/150 (26%)

Query: 229 APPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPP----RSPGAPG 284
           +P  PPPPPP          PSA  T ++L A+  + P  P PPP  PP    ++P  P 
Sbjct: 321 SPTPPPPPPP---------LPSALST-SSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370

Query: 285 GAR----TPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGIL 340
                   PG   +  P P        + S PP   A PV     T PVHP   G     
Sbjct: 371 PPAPLQIAPG---VLHPAPPPIAPPLVQPS-PPVARAAPVCE---TVPVHPLPQGE---- 419

Query: 341 LCAAGLPVCLTRAPKPILHPPPVSKSDVKP 370
               GLP      P P   PPP+    ++P
Sbjct: 420 --VQGLP-----PPPP---PPPLPPPGIRP 439



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 16/72 (22%)

Query: 227 PPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAP---------AAGPAEPAPPPGAPP 277
           PP PP PP PPPG       +RPS+  T  AL   P         A GP  P  PP  P 
Sbjct: 424 PPPPPPPPLPPPG-------IRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPS 476

Query: 278 RSPGAPGGARTP 289
           +   A    R P
Sbjct: 477 QVIPASEPKRHP 488



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 44/165 (26%), Positives = 54/165 (32%), Gaps = 22/165 (13%)

Query: 230 PPLPPPPPPGGPPGALAVRPSATFTGAALW----AAPAAGP----AEPAPPPGAPPRSPG 281
           P  PPPPPP    G     P+   +   L      +PA G       P PPP  PP    
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 282 APGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTGILL 341
               +      +   P         A A   P VP  P       G +HPA   +   L+
Sbjct: 335 LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLV 394

Query: 342 -----CAAGLPVCLTRAPKPI-------LHPPPVSKSDVKPVPGV 374
                 A   PVC T    P+       L PPP       P PG+
Sbjct: 395 QPSPPVARAAPVCETVPVHPLPQGEVQGLPPPP--PPPPLPPPGI 437



 Score = 30.0 bits (66), Expect = 6.6
 Identities = 30/114 (26%), Positives = 35/114 (30%), Gaps = 23/114 (20%)

Query: 266 PAEPAPPPGAPPRSPGAPGGARTPGQNNL--NRPGPQRT--TSVSARASIPPGVPALPVK 321
           P EP PPP         P          L  NRP    T  T V    + PP  P LP  
Sbjct: 275 PHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPVFVSPTPPPPPPPLPSA 334

Query: 322 NLNGTGPVHPALAGMTGILLCAAGLPVCLTRAPKPILHPPPVSKSDVKPVPGVP 375
                              L  + L   +T  P P + PPP   +     P VP
Sbjct: 335 -------------------LSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 4/112 (3%)

Query: 210 STRAASNAILASQRRKAPPAPPLPPPPPPGG--PPGALAVRPSATFTGAALWAAPAAGPA 267
           +T A  N+        APP P    P PP    PP   A  P+ + T  A     ++ P 
Sbjct: 152 ATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQA--PPSSSAPP 209

Query: 268 EPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALP 319
           E    P  PP +  AP  +  P +     P P  TT     +S PP   A+P
Sbjct: 210 ETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVP 261



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/151 (25%), Positives = 54/151 (35%), Gaps = 10/151 (6%)

Query: 178 PLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPP 237
           P      P S S P   ++  P          +T+A  ++    +   APP PP   P P
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPTPSA------TTQAPPSSSAPPETTAAPPTPPATTPAP 225

Query: 238 PGG--PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLN 295
           P    PP   A  P+ + T  A  ++ A  P E    P  P  +   P  A  P +    
Sbjct: 226 PSSSAPPETTAAPPTPSATTPAPLSSSA--PPETTAVPPTPSATTLDPSSASAPPETTAA 283

Query: 296 RPGPQRTTSVSARASIPPGVPALPVKNLNGT 326
            P P  TT     +  P    A P+   N +
Sbjct: 284 PPTPSATTPAPPSSPAPQETTAAPITTPNSS 314


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 42/106 (39%), Positives = 45/106 (42%), Gaps = 27/106 (25%)

Query: 213 AASNAILASQRRKAPPAPPLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPP 272
           AA+ A+L       PPA   PPPPPP  PP A A             AAPA+GP  PAPP
Sbjct: 62  AAAAALLLHPPPPPPPATAAPPPPPPPPPPPASA-------------AAPASGP--PAPP 106

Query: 273 PGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPAL 318
             A    PG  GGA          P P      SA A  P G  AL
Sbjct: 107 GLA--AGPGPAGGA----------PTPALVAGSSAAAPFPHGDSAL 140



 Score = 37.4 bits (85), Expect = 0.041
 Identities = 37/123 (30%), Positives = 42/123 (34%), Gaps = 26/123 (21%)

Query: 222 QRRKAPPAP-----------PLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPA 270
           Q++ +PP P           P PP    G  P   A  P     G  L AA AA    P 
Sbjct: 16  QQQLSPPPPAALAPVSGVVLPAPPAVSAGSSP---AGSPGGGAGGEGLGAAAAALLLHPP 72

Query: 271 PPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALPVKNLNGTGPVH 330
           PPP     +P  P             P P    S +A AS PP  P L        G   
Sbjct: 73  PPPPPATAAPPPPP------------PPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPT 120

Query: 331 PAL 333
           PAL
Sbjct: 121 PAL 123



 Score = 34.7 bits (78), Expect = 0.27
 Identities = 36/119 (30%), Positives = 42/119 (35%), Gaps = 21/119 (17%)

Query: 231 PLPPPPPPGGPPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSP-GAPGGARTP 289
           P PPPP        L+  P A         AP +G   PAPP  +   SP G+PGG    
Sbjct: 5   PPPPPPQQQQQQQQLSPPPPAAL-------APVSGVVLPAPPAVSAGSSPAGSPGGG--A 55

Query: 290 GQNNLNR----------PGPQRTTSVSARASIPPGVPALPVKNLNGTGPVHPALAGMTG 338
           G   L            P P   T+       PP  PA      +G  P  P LA   G
Sbjct: 56  GGEGLGAAAAALLLHPPPPPPPATAAPPPPPPPPPPPASAAAPASGP-PAPPGLAAGPG 113


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 4/112 (3%)

Query: 210 STRAASNAILASQRRKAPPAPPLPPPPPPGG--PPGALAVRPSATFTGAALWAAPAAGPA 267
           +T A  N+        APP P    P PP    PP   A  P+ + T  A     ++ P 
Sbjct: 152 ATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQA--PPSSSAPP 209

Query: 268 EPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALP 319
           E    P  PP +  AP  +  P +     P P  TT     +S PP   A+P
Sbjct: 210 ETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVP 261



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/151 (25%), Positives = 54/151 (35%), Gaps = 10/151 (6%)

Query: 178 PLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPP 237
           P      P S S P   ++  P          +T+A  ++    +   APP PP   P P
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPTPSA------TTQAPPSSSAPPETTAAPPTPPATTPAP 225

Query: 238 PGG--PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLN 295
           P    PP   A  P+ + T  A  ++ A  P E    P  P  +   P  A  P +    
Sbjct: 226 PSSSAPPETTAAPPTPSATTPAPLSSSA--PPETTAVPPTPSATTLDPSSASAPPETTAA 283

Query: 296 RPGPQRTTSVSARASIPPGVPALPVKNLNGT 326
            P P  TT     +  P    A P+   N +
Sbjct: 284 PPTPSATTPAPPSSPAPQETTAAPITTPNSS 314


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 4/112 (3%)

Query: 210 STRAASNAILASQRRKAPPAPPLPPPPPPGG--PPGALAVRPSATFTGAALWAAPAAGPA 267
           +T A  N+        APP P    P PP    PP   A  P+ + T  A     ++ P 
Sbjct: 152 ATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQA--PPSSSAPP 209

Query: 268 EPAPPPGAPPRSPGAPGGARTPGQNNLNRPGPQRTTSVSARASIPPGVPALP 319
           E    P  PP +  AP  +  P +     P P  TT     +S PP   A+P
Sbjct: 210 ETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVP 261



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 38/151 (25%), Positives = 54/151 (35%), Gaps = 10/151 (6%)

Query: 178 PLTVGSIPKSQSWPVGASSGQPCSCQQCLLVNSTRAASNAILASQRRKAPPAPPLPPPPP 237
           P      P S S P   ++  P          +T+A  ++    +   APP PP   P P
Sbjct: 172 PSATTPAPPSSSAPPETTAAPPTPSA------TTQAPPSSSAPPETTAAPPTPPATTPAP 225

Query: 238 PGG--PPGALAVRPSATFTGAALWAAPAAGPAEPAPPPGAPPRSPGAPGGARTPGQNNLN 295
           P    PP   A  P+ + T  A  ++ A  P E    P  P  +   P  A  P +    
Sbjct: 226 PSSSAPPETTAAPPTPSATTPAPLSSSA--PPETTAVPPTPSATTLDPSSASAPPETTAA 283

Query: 296 RPGPQRTTSVSARASIPPGVPALPVKNLNGT 326
            P P  TT     +  P    A P+   N +
Sbjct: 284 PPTPSATTPAPPSSPAPQETTAAPITTPNSS 314


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,206,659
Number of Sequences: 37866
Number of extensions: 2166397
Number of successful extensions: 41736
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 628
Number of HSP's successfully gapped in prelim test: 1554
Number of HSP's that attempted gapping in prelim test: 15823
Number of HSP's gapped (non-prelim): 12774
length of query: 620
length of database: 18,247,518
effective HSP length: 108
effective length of query: 512
effective length of database: 14,157,990
effective search space: 7248890880
effective search space used: 7248890880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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