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Search of human proteins with 41327760
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41327760 ATPase, class II, type 9B [Homo sapiens]
(1147 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 2283 0.0
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 1604 0.0
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 459 e-129
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 439 e-123
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 439 e-123
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 433 e-121
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 433 e-121
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 425 e-118
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 423 e-118
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 423 e-118
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 412 e-115
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 412 e-115
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 402 e-111
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 337 5e-92
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 273 5e-73
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 251 3e-66
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 233 6e-61
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 142 2e-33
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 86 3e-16
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 77 9e-14
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 75 5e-13
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 75 5e-13
gi|66932949 ATPase type 13A4 [Homo sapiens] 73 1e-12
gi|66730421 ATPase type 13A5 [Homo sapiens] 69 3e-11
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 69 3e-11
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 69 3e-11
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 69 3e-11
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 69 3e-11
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens] 69 3e-11
gi|148839292 ATPase type 13A3 [Homo sapiens] 69 3e-11
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 2283 bits (5917), Expect = 0.0
Identities = 1147/1147 (100%), Positives = 1147/1147 (100%)
Query: 1 MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEE 60
MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEE
Sbjct: 1 MADQIPLYPVRSAAAAAANRKRAAYYSAAGPRPGADRHSRYQLEDESAHLDEMPLMMSEE 60
Query: 61 GFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWL 120
GFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWL
Sbjct: 61 GFENEESDYHTLPRARIMQRKRGLEWFVCDGWKFLCTSCCGWLINICRRKKELKARTVWL 120
Query: 121 GCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY 180
GCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY
Sbjct: 121 GCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLY 180
Query: 181 TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIV 240
TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIV
Sbjct: 181 TYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIV 240
Query: 241 EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV 300
EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV
Sbjct: 241 EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV 300
Query: 301 YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV 360
YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV
Sbjct: 301 YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV 360
Query: 361 MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYII 420
MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYII
Sbjct: 361 MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYII 420
Query: 421 PISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIF 480
PISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIF
Sbjct: 421 PISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIF 480
Query: 481 KRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR 540
KRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR
Sbjct: 481 KRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR 540
Query: 541 IHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTES 600
IHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTES
Sbjct: 541 IHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTES 600
Query: 601 VGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD 660
VGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD
Sbjct: 601 VGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD 660
Query: 661 VAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK 720
VAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK
Sbjct: 661 VAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK 720
Query: 721 VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS 780
VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS
Sbjct: 721 VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS 780
Query: 781 HLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ 840
HLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ
Sbjct: 781 HLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQ 840
Query: 841 CPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS 900
CPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS
Sbjct: 841 CPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS 900
Query: 901 LAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL 960
LAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL
Sbjct: 901 LAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPL 960
Query: 961 YQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLIS 1020
YQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLIS
Sbjct: 961 YQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLIS 1020
Query: 1021 IYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCY 1080
IYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCY
Sbjct: 1021 IYQGGILMYGALVLFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCY 1080
Query: 1081 VSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPP 1140
VSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPP
Sbjct: 1081 VSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVVSCLPLYVLKYLRRKLSPP 1140
Query: 1141 SYCKLAS 1147
SYCKLAS
Sbjct: 1141 SYCKLAS 1147
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 1604 bits (4154), Expect = 0.0
Identities = 791/1049 (75%), Positives = 909/1049 (86%), Gaps = 25/1049 (2%)
Query: 99 CCGWLINICRRKKELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFL 158
CC WL C E + RTVWLG PEK ++++PRN I NQKYN FTF+PGVL+ QFK+F
Sbjct: 24 CCEWLR--CCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFF 81
Query: 159 NLYFLVISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSK 218
NLYFL+++CSQFVP +++G LYTYW PLGFVLAVT+ REA++E R + RDKEVNSQ+YS+
Sbjct: 82 NLYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSR 141
Query: 219 LTVRGKVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLK 278
LT RG V+VKSS+IQVGDLIIVEKNQR+P+DM+FLRTSEK GSCF+RTDQLDGETDWKL+
Sbjct: 142 LTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLR 201
Query: 279 VAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWAS 338
+ V+CTQ+LP DL I +YVYA++P +DIH+F GTFTREDSDPPI ESLSIENTLWA
Sbjct: 202 LPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAG 261
Query: 339 TIVASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTL 398
T+VASGTV+GVV+YTG+E RSVMNTSNP++K+GL DLE+N LTK LF ALV +S+VMV L
Sbjct: 262 TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVAL 321
Query: 399 QGFVGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEE 458
Q F G WY + RFLLLFS IIPISLRVNLDMGK VY W++ +D IPGTVVR+STIPE+
Sbjct: 322 QHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQ 381
Query: 459 LGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNT 518
LGR+ YLLTDKTGTLTQNEMIFKRLHLGTV+YG D+MDE+QSH+ Y+Q QSQ
Sbjct: 382 LGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSIYTQ-QSQ------ 434
Query: 519 GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFS 578
P +K + KVR+++SSR+HEAVKAI LCHNVTPVYES GVT++ AEA++ +
Sbjct: 435 -DPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESN-GVTDQ---AEAEKQYE 489
Query: 579 DENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESK 638
D R YQASSPDEVALVQWTESVGLTLV RD +SMQL+TP Q+L+F ILQ+FPFT ESK
Sbjct: 490 DSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESK 549
Query: 639 RMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEE 698
RMG+IVRDEST EITFYMKGADV M+ IVQYNDWLEEECGNMAREGLR LVVAKK+L EE
Sbjct: 550 RMGIIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGNMAREGLRVLVVAKKSLAEE 609
Query: 699 QYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNA 758
QYQDFE+RY QAKLS+HDRSLKVA V+ESLE EMELLCLTGVEDQLQADVRPTLE LRNA
Sbjct: 610 QYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNA 669
Query: 759 GIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVI 818
GIK+WMLTGDKLETATC AK++HLV+R QDIH+FR VT+RGEAHLELNAFRRKHDCALVI
Sbjct: 670 GIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVTNRGEAHLELNAFRRKHDCALVI 729
Query: 819 SGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGND 878
SGDSLEVCLKYYE+EF+ELACQCPAVVCCRC+PTQKA+IV LLQ+ TG+ TCA+GDGGND
Sbjct: 730 SGDSLEVCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGND 789
Query: 879 VSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHR 938
VSMIQ +DCG+G+EGKEGKQASLAADFSITQF+H+GRLLMVHGRNSYKRSAAL QFV+HR
Sbjct: 790 VSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHR 849
Query: 939 GLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPEL 998
L ISTMQAVFSSVFYFASVPLYQGFL++GY+TIYTMFPVFSLVLD+DVK E+AMLYPEL
Sbjct: 850 SLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSLVLDKDVKSEVAMLYPEL 909
Query: 999 YKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAISFTALILTELLMV 1058
YKDL KGR LS+KTFLIWVLISIYQG +MYGAL+LFESEFVH+VAISFT+LILTELLMV
Sbjct: 910 YKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVAISFTSLILTELLMV 969
Query: 1059 ALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSFGAFLDVAFITTVTFLWKVSA 1118
ALT++TWHWLM VAE LSL CY++SL FL+E F+DV FI T++FLWKVS
Sbjct: 970 ALTIQTWHWLMTVAELLSLACYIASLVFLHE-----------FIDVYFIATLSFLWKVSV 1018
Query: 1119 ITVVSCLPLYVLKYLRRKLSPPSYCKLAS 1147
IT+VSCLPLYVLKYLRR+ SPPSY KL S
Sbjct: 1019 ITLVSCLPLYVLKYLRRRFSPPSYSKLTS 1047
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 459 bits (1181), Expect = e-129
Identities = 325/1080 (30%), Positives = 533/1080 (49%), Gaps = 81/1080 (7%)
Query: 128 EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLG 187
+K N I + KY V+ F+P L+EQF+ N YFL+I Q + + T PL
Sbjct: 37 QKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSPV-TSGLPLF 95
Query: 188 FVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIP 247
FV+ VT ++ +++ R D EVN + G V+ +S +I+VGD++ + K++ P
Sbjct: 96 FVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFP 155
Query: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQM 307
+D+V L + GSC + T LDGET+ K VAV T L + +L ++ A + Q+P+
Sbjct: 156 ADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQTVANLDTLVAVIECQQPEA 215
Query: 308 DIHSFEGTFTREDSDPPIHESLSIENTLW-ASTIVASGTVIGVVIYTGKETRSVMNTSNP 366
D++ F G I L E+ L + + + + GV +YTG ET+ +N +
Sbjct: 216 DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275
Query: 367 KNKVGLLDLELNRLTKALFLALVALSIVMVTL-------QGFVGPWYR------------ 407
K ++ +N + L++ +++ L + + PWY
Sbjct: 276 SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335
Query: 408 -----NLFRFLLLFSYIIPISLRVNLDM----GKAVYGWMM--MKDENIPGTVVRTSTIP 456
+ FL+L+++IIPISL V ++M G GW + +E+ V TS +
Sbjct: 336 LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395
Query: 457 EELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYG---------ADTMDEIQSHVRDSYS 507
EELG++ Y+ TDKTGTLT+NEM F+ + + Y T D + ++ S
Sbjct: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNL----S 451
Query: 508 QMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEE 567
+ S + NN + ++P+ + KA+ LCH V + T+
Sbjct: 452 YLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAVSLCHTV----QISNVQTDC 507
Query: 568 TEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCI 627
T + + Y ASSPDE ALV+ +G+ + +M++KT G++ + +
Sbjct: 508 TGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKT-LGKLERYKL 566
Query: 628 LQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSP--IVQYNDWLEEECGNMAREGL 685
L + F S+ +RM VIV+ S ++ F KGA+ ++ P I + A +GL
Sbjct: 567 LHILEFDSDRRRMSVIVQAPSGEKLLF-AKGAESSILPKCIGGEIEKTRIHVDEFALKGL 625
Query: 686 RTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQ 745
RTL +A + T ++Y++ + R +A+ ++ R K+AAV + +E+++ LL T VED+LQ
Sbjct: 626 RTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQ 685
Query: 746 ADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLEL 805
VR T+E LR AGIK+W+LTGDK ETA ++ S RT +I S E +L
Sbjct: 686 DKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSDSECAEQL 745
Query: 806 NAFRRK------HDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVT 859
R+ LV+ G SL + L+ +E F+E+ C AV+CCR +P QKA+++
Sbjct: 746 RQLARRITEDHVIQHGLVVDGTSLSLALREHEKLFMEVCRNCSAVLCCRMAPLQKAKVIR 805
Query: 860 LLQQHTGRR-TCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLM 918
L++ + T A+GDG NDVSMIQ A GIGI GKEG+QA+ +D++I +F+ + +LL
Sbjct: 806 LIKISPEKPITLAVGDGANDVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLF 865
Query: 919 VHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPV 978
VHG Y R A L Q+ ++ + T Q ++ F+ LY + Y +T P+
Sbjct: 866 VHGHFYYIRIATLVQYFFYKNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPI 925
Query: 979 FSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFES 1037
+L+Q V P + P LY+D++K R LS KTFL W ++ I +G+ +L
Sbjct: 926 LIYSLLEQHVDPHVLQNKPTLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGK 985
Query: 1038 EFVHV-----------VAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAF 1086
+ + + FT +++T + +AL W W + ++ G + F
Sbjct: 986 DTSLLGNGQMFGNWTFGTLVFTVMVITVTVKMALETHFWTW---INHLVTWGSIIFYFVF 1042
Query: 1087 LNEYFGIGRVSFGA----FLDVAFITTVTFLWKVSAITVVSCLPLYVL-KYLRRKLSPPS 1141
Y GI G+ F+ + +++ + W + VV+CL L ++ K R L P S
Sbjct: 1043 SLFYGGILWPFLGSQNMYFVFIQLLSSGS-AWFAIILMVVTCLFLDIIKKVFDRHLHPTS 1101
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 439 bits (1130), Expect = e-123
Identities = 310/1027 (30%), Positives = 504/1027 (49%), Gaps = 116/1027 (11%)
Query: 114 KARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPA 173
+ RT+++ P+ K N + KYN+ TF+P LY QF+ N +FL I+ Q +P
Sbjct: 35 EVRTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPD 92
Query: 174 LKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQ 233
+ YT PL F+LAV +E I++ +R + D VN + L V +
Sbjct: 93 VSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVN 152
Query: 234 VGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDL 293
VGD++I++ + IP+D V L +SE C+I T LDGET+ K++ + T + + L
Sbjct: 153 VGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSL 212
Query: 294 FSISAYVYAQKPQMDIHSFEGTFTRED-------SDPPIHESLSIENTLWASTIVASGTV 346
IS + + P ++ F G + +D + + NT W V
Sbjct: 213 MRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------V 263
Query: 347 IGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG--- 403
G+V+YTG +T+ + N+++P K+ ++ N LF L+A+S+V
Sbjct: 264 HGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRH 323
Query: 404 ---PWYRNL------------FRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENI--- 445
WY NL F++LF+ +IPISL V L++ K + + D ++
Sbjct: 324 SGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYE 383
Query: 446 ---PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
+ RTS + EELG++ Y+ +DKTGTLT N M FK+ + V+YG +
Sbjct: 384 PTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQN--------- 434
Query: 503 RDSYSQMQSQAGGNNT--GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYES 560
SQ G T S+ L Q++ P + I E + + +CH P E
Sbjct: 435 --------SQFGDEKTFSDSSLLENLQNNHP-----TAPIICEFLTMMAVCHTAVPEREG 481
Query: 561 RAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSG 620
+ YQA+SPDE ALV+ + + R S+ + + G
Sbjct: 482 -------------------DKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDS-LG 521
Query: 621 QVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVA----MSPIVQYNDWLEEE 676
Q + +L + FTS KRM VIVR S ++ Y KGAD ++ +Y + +
Sbjct: 522 QEERYELLNVLEFTSARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKH 580
Query: 677 CGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLC 736
A EGLRTL A ++E +Q++ + Y +A S+ +R LK+ E +E+ ++LL
Sbjct: 581 LEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLG 640
Query: 737 LTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIF---- 792
T +ED+LQ V T+E L A IKIW+LTGDK ETA I S L+ + + +
Sbjct: 641 ATAIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGS 700
Query: 793 ----RQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHE-FVELACQCPAVVCC 847
R+ SR L +A R+++D AL+I G +L+ L + + F++LA C AV+CC
Sbjct: 701 LDGTRETLSRHCTTLG-DALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICC 759
Query: 848 RCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSI 907
R SP QK+ +V ++++ T AIGDG NDVSMIQ A G+GI G EG QA+ ++D+SI
Sbjct: 760 RVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSI 819
Query: 908 TQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMV 967
QF+++ LLM+HG +Y R + + ++ +++ ++ F+ V F+ L++ + +
Sbjct: 820 AQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIG 879
Query: 968 GYATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWV--LISIYQG 1024
Y ++T P +L + ++ + E + YPELYK T +L F T + WV L ++
Sbjct: 880 LYNVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALDFNTKVFWVHCLNGLFHS 937
Query: 1025 GILMYGALVLFE----------SEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEF 1074
IL + L + S+++ + +T +++T L L W W +A +
Sbjct: 938 VILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIW 997
Query: 1075 LSLGCYV 1081
S+ +V
Sbjct: 998 GSIALWV 1004
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 439 bits (1128), Expect = e-123
Identities = 306/1025 (29%), Positives = 503/1025 (49%), Gaps = 97/1025 (9%)
Query: 114 KARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPA 173
+ RT+++ P+ K N + KYN+ TF+P LY QF+ N +FL I+ Q +P
Sbjct: 35 EVRTIFINQPQLT--KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPD 92
Query: 174 LKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQ 233
+ YT PL F+LAV +E I++ +R + D VN + L V +
Sbjct: 93 VSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVA 152
Query: 234 VGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDL 293
VG+++ V + +P+D++ L +SE C+I T LDGET+ K++ + T + + L
Sbjct: 153 VGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSL 212
Query: 294 FSISAYVYAQKPQMDIHSFEGTFTRED-------SDPPIHESLSIENTLWASTIVASGTV 346
IS + + P ++ F G + +D + + NT W V
Sbjct: 213 MRISGRIECESPNRHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQW---------V 263
Query: 347 IGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG--- 403
G+V+YTG +T+ + N+++P K+ ++ N LF L+A+S+V
Sbjct: 264 HGIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRH 323
Query: 404 ---PWYRNL------------FRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENI--- 445
WY NL F++LF+ +IPISL V L++ K + + D ++
Sbjct: 324 SGKDWYLNLNYGGASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYE 383
Query: 446 ---PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
+ RTS + EELG++ Y+ +DKTGTLT N M FK+ + V+YG E
Sbjct: 384 PTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCS 443
Query: 503 RDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA 562
D + Q + S+ L Q++ P + I E + + +CH P E
Sbjct: 444 PDEWQNSQFGDEKTFSDSSLLENLQNNHP-----TAPIICEFLTMMAVCHTAVPEREG-- 496
Query: 563 GVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQV 622
+ YQA+SPDE ALV+ + + R S+ + + GQ
Sbjct: 497 -----------------DKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDS-LGQE 538
Query: 623 LSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVA----MSPIVQYNDWLEEECG 678
+ +L + FTS KRM VIVR S ++ Y KGAD ++ +Y + +
Sbjct: 539 ERYELLNVLEFTSARKRMSVIVRTPS-GKLRLYCKGADTVIYDRLAETSKYKEITLKHLE 597
Query: 679 NMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLT 738
A EGLRTL A ++E +Q++ + Y +A S+ +R LK+ E +E+ ++LL T
Sbjct: 598 QFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGAT 657
Query: 739 GVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIF------ 792
+ED+LQ V T+E L A IKIW+LTGDK ETA I S L+ + + +
Sbjct: 658 AIEDKLQDQVPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLD 717
Query: 793 --RQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKYYEHE-FVELACQCPAVVCCRC 849
R+ SR L +A R+++D AL+I G +L+ L + + F++LA C AV+CCR
Sbjct: 718 GTRETLSRHCTTLG-DALRKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICCRV 776
Query: 850 SPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQ 909
SP QK+ +V ++++ T AIGDG NDVSMIQ A G+GI G EG QA+ ++D+SI Q
Sbjct: 777 SPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQ 836
Query: 910 FRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGY 969
F+++ LLM+HG +Y R + + ++ +++ ++ F+ V F+ L++ + + Y
Sbjct: 837 FKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLY 896
Query: 970 ATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWV--LISIYQGGI 1026
++T P +L + ++ + E + YPELYK T +L F T + WV L ++ I
Sbjct: 897 NVMFTAMPPLTLGIFERSCRKENMLKYPELYK--TSQNALDFNTKVFWVHCLNGLFHSVI 954
Query: 1027 LMYGALVLFE----------SEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLS 1076
L + L + S+++ + +T +++T L L W W +A + S
Sbjct: 955 LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 1014
Query: 1077 LGCYV 1081
+ +V
Sbjct: 1015 IALWV 1019
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 433 bits (1114), Expect = e-121
Identities = 324/1111 (29%), Positives = 536/1111 (48%), Gaps = 117/1111 (10%)
Query: 115 ARTVWLGCPEK-------CEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISC 167
+RT+++G E +++P N I + KY + FIP L+EQF+ N YFL+I
Sbjct: 23 SRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFL 82
Query: 168 SQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGK-VQ 226
Q + + T PL FV+ VT ++ +++ R + D +N Q GK V+
Sbjct: 83 VQLIIDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHKADNAMN-QCPVHFIQHGKLVR 140
Query: 227 VKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQ 286
+S ++VGD+++V++++ P D++FL ++ G+C + T LDGE+ K AV T+
Sbjct: 141 KQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKG 200
Query: 287 LPALGDLFSISAYVYAQKPQMDIHSFEGTFT-REDSDPPIHESLSIENTLW-ASTIVASG 344
D+ + A + ++PQ D++ F G D + P+ L EN L +T+ +
Sbjct: 201 FHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTE 260
Query: 345 TVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG- 403
+ GV IYTG ET+ +N + K ++ +N L++ +++ L+
Sbjct: 261 KIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQS 320
Query: 404 ------PWY---------RNLF--------RFLLLFSYIIPISLRVNLDMGKAVYGWMMM 440
PWY RNLF F++LF+YIIP+S+ V ++M K + + +
Sbjct: 321 EPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFIT 380
Query: 441 KDENI------PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADT 494
DE++ G +V TS + EELG++ Y+ TDKTGTLT+N M FK
Sbjct: 381 WDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECC---------- 430
Query: 495 MDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNV 554
I+ HV + Q ++G + + S + R+ + R A+ LCH V
Sbjct: 431 ---IEGHVYVPHVICNGQVLPESSGIDMIDSSPSVNGREREELFFR------ALCLCHTV 481
Query: 555 TPVYESRAGVTEETEFAEADQDFSDENRT--YQASSPDEVALVQWTESVGLTLVSRDLTS 612
++ + + + D ++ Y +SSPDEVALV+ + +G T +
Sbjct: 482 Q---------VKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNY 532
Query: 613 MQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYN-- 670
M++ + F +L++ F S +RM VIV+ +T EI + KGAD ++ P V
Sbjct: 533 MEILNRENHIERFELLEILSFDSVRRRMSVIVKS-ATGEIYLFCKGADSSIFPRVIEGKV 591
Query: 671 DWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLER 730
D + A EGLRTL VA K L +E+Y+ AK+++ DR K+A E +E+
Sbjct: 592 DQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEK 651
Query: 731 EMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSR-TQDI 789
++ LL T VED+LQ T+E L+ AGIK+W+LTGDK+ETA + L R TQ +
Sbjct: 652 DLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLL 711
Query: 790 HIFRQVTSRGEAH---LELNAFRRKH-----------------DCALVISGDSLEVCLK- 828
+ + H EL+ +H D L+I G +L + +K
Sbjct: 712 ELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKP 771
Query: 829 -------YYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQ-QHTGRRTCAIGDGGNDVS 880
Y F+E+ C AV+CCR +P QKA+IV L++ T AIGDG NDVS
Sbjct: 772 REDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVS 831
Query: 881 MIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGL 940
MI A GIG+ GKEG+QA+ +D++I +F+H+ ++L+VHG Y R + L Q+ ++ +
Sbjct: 832 MILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNV 891
Query: 941 IISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAMLYPELY 999
Q ++ F+ LY + Y +T P+ +++Q V ++ P LY
Sbjct: 892 CFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLY 951
Query: 1000 KDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFV----------HVVAISFTA 1049
+D+ K L ++ F+ W L+ ++ + +GA +FE+ V + FT
Sbjct: 952 RDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTV 1011
Query: 1050 LILTELLMVALTVRTWHWLMVVAEFLSLGCY-VSSLAFLNEYFGIGRVSFGAFLDVAFIT 1108
++ T L +AL W W+ + SL Y V SL + + ++ + ++
Sbjct: 1012 MVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLS 1071
Query: 1109 TVTFLWKVSAITVVSCLPLYVLKYLRRKLSP 1139
+ + + +S LP + K L R+L P
Sbjct: 1072 SGPAWLAIVLLVTISLLPDVLKKVLCRQLWP 1102
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 433 bits (1114), Expect = e-121
Identities = 324/1111 (29%), Positives = 536/1111 (48%), Gaps = 117/1111 (10%)
Query: 115 ARTVWLGCPEK-------CEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISC 167
+RT+++G E +++P N I + KY + FIP L+EQF+ N YFL+I
Sbjct: 23 SRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFL 82
Query: 168 SQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGK-VQ 226
Q + + T PL FV+ VT ++ +++ R + D +N Q GK V+
Sbjct: 83 VQLIIDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHKADNAMN-QCPVHFIQHGKLVR 140
Query: 227 VKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQ 286
+S ++VGD+++V++++ P D++FL ++ G+C + T LDGE+ K AV T+
Sbjct: 141 KQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKG 200
Query: 287 LPALGDLFSISAYVYAQKPQMDIHSFEGTFT-REDSDPPIHESLSIENTLW-ASTIVASG 344
D+ + A + ++PQ D++ F G D + P+ L EN L +T+ +
Sbjct: 201 FHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTE 260
Query: 345 TVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG- 403
+ GV IYTG ET+ +N + K ++ +N L++ +++ L+
Sbjct: 261 KIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQS 320
Query: 404 ------PWY---------RNLF--------RFLLLFSYIIPISLRVNLDMGKAVYGWMMM 440
PWY RNLF F++LF+YIIP+S+ V ++M K + + +
Sbjct: 321 EPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFIT 380
Query: 441 KDENI------PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADT 494
DE++ G +V TS + EELG++ Y+ TDKTGTLT+N M FK
Sbjct: 381 WDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECC---------- 430
Query: 495 MDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNV 554
I+ HV + Q ++G + + S + R+ + R A+ LCH V
Sbjct: 431 ---IEGHVYVPHVICNGQVLPESSGIDMIDSSPSVNGREREELFFR------ALCLCHTV 481
Query: 555 TPVYESRAGVTEETEFAEADQDFSDENRT--YQASSPDEVALVQWTESVGLTLVSRDLTS 612
++ + + + D ++ Y +SSPDEVALV+ + +G T +
Sbjct: 482 Q---------VKDDDSVDGPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNY 532
Query: 613 MQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYN-- 670
M++ + F +L++ F S +RM VIV+ +T EI + KGAD ++ P V
Sbjct: 533 MEILNRENHIERFELLEILSFDSVRRRMSVIVKS-ATGEIYLFCKGADSSIFPRVIEGKV 591
Query: 671 DWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLER 730
D + A EGLRTL VA K L +E+Y+ AK+++ DR K+A E +E+
Sbjct: 592 DQIRARVERNAVEGLRTLCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEK 651
Query: 731 EMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSR-TQDI 789
++ LL T VED+LQ T+E L+ AGIK+W+LTGDK+ETA + L R TQ +
Sbjct: 652 DLTLLGATAVEDRLQEKAADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLL 711
Query: 790 HIFRQVTSRGEAH---LELNAFRRKH-----------------DCALVISGDSLEVCLK- 828
+ + H EL+ +H D L+I G +L + +K
Sbjct: 712 ELTTKRIEEQSLHDVLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKP 771
Query: 829 -------YYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQ-QHTGRRTCAIGDGGNDVS 880
Y F+E+ C AV+CCR +P QKA+IV L++ T AIGDG NDVS
Sbjct: 772 REDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVS 831
Query: 881 MIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGL 940
MI A GIG+ GKEG+QA+ +D++I +F+H+ ++L+VHG Y R + L Q+ ++ +
Sbjct: 832 MILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNV 891
Query: 941 IISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAMLYPELY 999
Q ++ F+ LY + Y +T P+ +++Q V ++ P LY
Sbjct: 892 CFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLY 951
Query: 1000 KDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFV----------HVVAISFTA 1049
+D+ K L ++ F+ W L+ ++ + +GA +FE+ V + FT
Sbjct: 952 RDVAKNALLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTV 1011
Query: 1050 LILTELLMVALTVRTWHWLMVVAEFLSLGCY-VSSLAFLNEYFGIGRVSFGAFLDVAFIT 1108
++ T L +AL W W+ + SL Y V SL + + ++ + ++
Sbjct: 1012 MVFTVTLKLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLS 1071
Query: 1109 TVTFLWKVSAITVVSCLPLYVLKYLRRKLSP 1139
+ + + +S LP + K L R+L P
Sbjct: 1072 SGPAWLAIVLLVTISLLPDVLKKVLCRQLWP 1102
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 425 bits (1092), Expect = e-118
Identities = 336/1127 (29%), Positives = 545/1127 (48%), Gaps = 129/1127 (11%)
Query: 107 CRRKKELKARTVWLGCPEKCEEK--HPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLV 164
C KK + + + EK + N I KYN+ TF+P L+EQF+ N YFL
Sbjct: 3 CSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLC 62
Query: 165 ISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGK 224
+ Q +P + +T PL V+ +T ++A D++ R + D +VN++ S++ + K
Sbjct: 63 LLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNR-QSEVLINSK 121
Query: 225 VQ-VKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSC 283
+Q K +++VGD+I +E NQ + +D++ L +SE G C++ T +LDGET+ K++ A+S
Sbjct: 122 LQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSV 181
Query: 284 TQQLPA-LGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVA 342
T +L A + L V + P + F G + +DS SL+ E + I+
Sbjct: 182 TSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSK----HSLNNEKIILRGCILR 237
Query: 343 SGT-VIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVT---- 397
+ + G+VI+ G +T+ + N+ K K +D +N L +F L+ L I++
Sbjct: 238 NTSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSI 297
Query: 398 LQGFVGPWYRNLF------------RFLLLFSYII------PISLRVNLDMGKAVYGWMM 439
+ G +R FL +SYII PISL V++++ + + + +
Sbjct: 298 WESQTGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFI 357
Query: 440 MKDEN-------IPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGA 492
D IP V RT+T+ EELG++ Y+ +DKTGTLTQN M FKR + YG
Sbjct: 358 NWDRKMYYSRKAIPA-VARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGE 416
Query: 493 -----DTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSS---RIHEA 544
D EI ++SQA R+ Q + +S+ ++HE
Sbjct: 417 VHDDLDQKTEITQEKEPVDFSVKSQAD---------REFQFFDHHLMESIKMGDPKVHEF 467
Query: 545 VKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLT 604
++ + LCH V ++EE E YQ SPDE ALV + G
Sbjct: 468 LRLLALCHTV---------MSEENSAGEL---------IYQVQSPDEGALVTAARNFGFI 509
Query: 605 LVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD-VAM 663
SR ++ ++ G ++++ +L F + KRM VIVR+ +I Y KGAD +
Sbjct: 510 FKSRTPETITIEE-LGTLVTYQLLAFLDFNNTRKRMSVIVRNPE-GQIKLYSKGADTILF 567
Query: 664 SPIVQYNDWL----EEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSL 719
+ N+ L + A EGLRTL +A + L ++ ++++ A + +R
Sbjct: 568 EKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDE 627
Query: 720 KVAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKS 779
++A + E +ER++ LL T VED+LQ V T+ L A IKIW+LTGDK ETA I +
Sbjct: 628 RIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYA 687
Query: 780 SHLVS---------------------RTQDIHIFRQVTSRGEAH--------LELNAFRR 810
++++ R ++F Q + H LEL++
Sbjct: 688 CNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVE 747
Query: 811 KH---DCALVISGDSLEVCLKY-YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTG 866
+ D AL+I+G SL L+ +++ +ELAC C V+CCR +P QKA++V L++++
Sbjct: 748 ETITGDYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRN 807
Query: 867 RRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYK 926
T AIGDG NDVSMI++A G+GI G+EG QA LA+D+S QFR++ RLL+VHGR SY
Sbjct: 808 AVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYF 867
Query: 927 RSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQ 985
R + ++ + + F F++ +Y + + + +YT PV ++ + DQ
Sbjct: 868 RMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQ 927
Query: 986 DVKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILM---YGALVLFESE---- 1038
DV + ++ P+LYK + + F I VL IY +L YGA E
Sbjct: 928 DVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQH 987
Query: 1039 ---FVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFL--NEYFGI 1093
+ T+L++ + +AL W ++ V + S+ Y S L + N FGI
Sbjct: 988 IADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGI 1047
Query: 1094 GRVSFGAFLDVAFITTVTFLWKVSAI-TVVSCLPLYVLKYLRRKLSP 1139
F + T +W V + TV S +P+ ++L+ L P
Sbjct: 1048 FPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYP 1094
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 423 bits (1087), Expect = e-118
Identities = 329/1098 (29%), Positives = 525/1098 (47%), Gaps = 119/1098 (10%)
Query: 129 KHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGF 188
++ N IK KYN+ TF+P L+EQF+ N YFL + Q +P + +T PL
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 189 VLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKS-SDIQVGDLIIVEKNQRIP 247
VL +T ++A D++ R + D +VN++ S++ + G +Q + ++ VGD+I +E NQ +
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 179
Query: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQM 307
+D++ L +SE G C+I T +LDGET+ K++ A+ T +L + L V + P
Sbjct: 180 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 239
Query: 308 DIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGT-VIGVVIYTGKETRSVMNTSNP 366
+ F GT +++ P LS +N L ++ + G+VI+ G +T+ + N+
Sbjct: 240 KLDKFSGTLYWKENKFP----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
Query: 367 KNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF----VG-------PW---------- 405
K K +D +N L +F LV + +++ VG PW
Sbjct: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 355
Query: 406 -YRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENI------PGTVVRTSTIPEE 458
+ + + ++++ + ++PISL V++++ + + + + D+ + RT+T+ EE
Sbjct: 356 GFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEE 415
Query: 459 LGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNT 518
LG++ Y+ +DKTGTLTQN M+F + + SYG D D + N
Sbjct: 416 LGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYG-DVFDVLGHKAELGERPEPVDFSFNPL 474
Query: 519 GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFS 578
S + K HE + + LCH V ++EE E
Sbjct: 475 ADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTV---------MSEEKNEGEL----- 520
Query: 579 DENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESK 638
Y+A SPDE ALV + G SR ++ + G +++ +L + F + K
Sbjct: 521 ----YYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHE-MGTAITYQLLAILDFNNIRK 575
Query: 639 RMGVIVRDESTAEITFYMKGADVAMSPIVQYN---------DWLEEECGNMAREGLRTLV 689
RM VIVR+ +I Y KGAD + + ++ D L E G EGLRTLV
Sbjct: 576 RMSVIVRNPE-GKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAG----EGLRTLV 630
Query: 690 VAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVR 749
+A K L EE Y+++ R QA L+ R ++A++ E +E M LL T +ED+LQ V
Sbjct: 631 LAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVP 690
Query: 750 PTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRG--EAHLELNA 807
T+ +L A IKIW+LTGDK ETA I S ++ T D+ VT E EL
Sbjct: 691 ETIALLTLANIKIWVLTGDKQETAVNIGYSCKML--TDDMTEVFIVTGHTVLEVREELRK 748
Query: 808 FRRKH-------------------------------DCALVISGDSLEVCLKY-YEHEFV 835
R K + ALVI+G SL L+ E EF+
Sbjct: 749 AREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFL 808
Query: 836 ELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKE 895
E AC C AV+CCR +P QKA++V L++++ T AIGDG NDVSMI+ A G+GI G+E
Sbjct: 809 ETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQE 868
Query: 896 GKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYF 955
G QA LA+D+S +QF+ + RLL+VHGR SY R + ++ + + F F
Sbjct: 869 GIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGF 928
Query: 956 ASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFL 1014
++ +Y + + Y +YT PV ++ V DQDV + +M YP+LY+ + + F
Sbjct: 929 SAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFF 988
Query: 1015 IWVLISIYQGGILM---YGALVLFESEFVHVVA--ISFTALILTELLMVA---LTVRTWH 1066
I + IY ++ YG + +A SF + T L++V + + T +
Sbjct: 989 ICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGY 1048
Query: 1067 WLMVVAEFL--SLGCYVSSLAFL--NEYFGIGRVSFGAFLDVAFITTVTFLWKVSAITVV 1122
W + F+ SL Y + L + N F + F + +W +T V
Sbjct: 1049 WTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTV 1108
Query: 1123 SC-LPLYVLKYLRRKLSP 1139
C +P+ ++LR L P
Sbjct: 1109 VCIMPVVAFRFLRLNLKP 1126
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 423 bits (1087), Expect = e-118
Identities = 313/1046 (29%), Positives = 503/1046 (48%), Gaps = 117/1046 (11%)
Query: 112 ELKARTVWLGCPEKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFV 171
E ART++L P K N I KY+V TF+P LYEQ + N +FL I+ Q +
Sbjct: 52 EAPARTIYLNQPHL--NKFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQI 109
Query: 172 PALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSD 231
P + YT PL +L + +E +++F+R + D VN + L + +
Sbjct: 110 PDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKE 169
Query: 232 IQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALG 291
+ VGD++ V Q +P+D+V L +SE C++ T LDGET+ K++ +S T +
Sbjct: 170 VAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTRE 229
Query: 292 DLFSISAYVYAQKPQMDIHSFEGTFTREDS-------DPPIHESLSIENTLWASTIVASG 344
L +S + + P ++ F G + D + + NT W
Sbjct: 230 VLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQW-------- 281
Query: 345 TVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG- 403
V G+V+YTG +T+ + N++ K L + ++T L L + +VM +
Sbjct: 282 -VFGIVVYTGHDTKLMQNST----KAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGAL 336
Query: 404 ---------PWY------------RNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKD 442
WY NL F++L++ +IPISL V L++ K + D
Sbjct: 337 YWNRSHGEKNWYIKKMDTTSDNFGYNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWD 396
Query: 443 E------NIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMD 496
N + RTS + EELG++ YL +DKTGTLT N M FK+ + V+YG +
Sbjct: 397 TDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYG-HFPE 455
Query: 497 EIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSR------IHEAVKAIVL 550
+ D + +M + P++ K++ R I E + + +
Sbjct: 456 LAREPSSDDFCRMPPPCSDS---------CDFDDPRLLKNIEDRHPTAPCIQEFLTLLAV 506
Query: 551 CHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDL 610
CH V P E D D N YQASSPDE ALV+ + +G +R
Sbjct: 507 CHTVVP---------------EKDGD----NIIYQASSPDEAALVKGAKKLGFVFTARTP 547
Query: 611 TSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD-VAMSPIVQY 669
S+ ++ GQ +F IL + F+S+ KRM VIVR S + Y KGAD V + +
Sbjct: 548 FSVIIEA-MGQEQTFGILNVLEFSSDRKRMSVIVRTPS-GRLRLYCKGADNVIFERLSKD 605
Query: 670 NDWLEEECGNM---AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVE 726
+ ++EE ++ A EGLRTL VA L+E +Y+++ Y +A + DR+ ++ E
Sbjct: 606 SKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYE 665
Query: 727 SLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRT 786
+E+ + LL T +ED+LQA V T+ L A IKIW+LTGDK ETA I S LVS+
Sbjct: 666 IIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQN 725
Query: 787 QDIHIFRQVT---SRGEAHLEL----NAFRRKHDCALVISGDSLEVCLKY-YEHEFVELA 838
+ + ++ + +R N +++D AL+I G +L+ L + F++LA
Sbjct: 726 MALILLKEDSLDATRAAITQHCTDLGNLLGKENDVALIIDGHTLKYALSFEVRRSFLDLA 785
Query: 839 CQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQ 898
C AV+CCR SP QK+ IV ++++ T AIGDG NDV MIQ A G+GI G EG Q
Sbjct: 786 LSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQ 845
Query: 899 ASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASV 958
A+ +D++I QF ++ +LL+VHG SY R + ++ +++ ++ F+ V F+
Sbjct: 846 ATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQ 905
Query: 959 PLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIWV 1017
L++ + + Y I+T P F+L + ++ E + +P+LYK G + K F
Sbjct: 906 ILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHC 965
Query: 1018 LISIYQGGILMYGALVLFE----------SEFVHVVAISFTALILTELLMVALTVRTWHW 1067
+ ++ IL + + E ++++ V I +T +++T L L W
Sbjct: 966 INALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTAW-- 1023
Query: 1068 LMVVAEFLSLGCYVSSLAFLNEYFGI 1093
+F L + S L +L +FGI
Sbjct: 1024 ----TKFSHLAVWGSMLTWL-VFFGI 1044
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 412 bits (1059), Expect = e-115
Identities = 314/1121 (28%), Positives = 526/1121 (46%), Gaps = 135/1121 (12%)
Query: 110 KKELKARTVWLGCPEKCE------EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFL 163
+K + RTV++G E ++ N I + KY ++ F+P L+EQF+ N YFL
Sbjct: 17 EKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFL 76
Query: 164 VISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRG 223
+I Q + T PL FV+ VT ++ +++ R + D EVN +
Sbjct: 77 IIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAK 135
Query: 224 KVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSC 283
+V+ +S I+VGD++ V+ ++ P D++ L + G+C++ T LDGE++ K AV
Sbjct: 136 RVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRD 195
Query: 284 TQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFT-REDSDPPIHESLSIENTLW-ASTIV 341
T L + ++ A + ++PQ D++ F G +S + SL EN L +T+
Sbjct: 196 TIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLK 255
Query: 342 ASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF 401
+ + GV +YTG ET+ +N K ++ +N L+ + V TL+ +
Sbjct: 256 NTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK-Y 314
Query: 402 VG--------PWYR-----------------NLFRFLLLFSYIIPISLRVNLDMGKAVYG 436
V PWY + F++LF++IIP+S+ V ++M K +
Sbjct: 315 VWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGS 374
Query: 437 WMMMKDENI------PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSY 490
+ + D++ G +V TS + EELG++ Y+ TDKTGTLT+N M F + Y
Sbjct: 375 FFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
Query: 491 GADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVL 550
T + SQ G T + K +R ++A+ L
Sbjct: 435 KGVTQEV----------DGLSQTDGTLTYFDKVDK-------------NREELFLRALCL 471
Query: 551 CHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDL 610
CH V ++ V TE AE TY +SSPDE+ALV+ + G T +
Sbjct: 472 CHTVE--IKTNDAVDGATESAEL---------TYISSSPDEIALVKGAKRYGFTFLGNRN 520
Query: 611 TSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYN 670
M+++ ++ + +L F + +RM VIV+ + +I + KGAD A+ P VQ +
Sbjct: 521 GYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNH 579
Query: 671 D--WLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESL 728
+ + A +G RTL VA K + + Y+ + +AK+++ DR K+ V + +
Sbjct: 580 EIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDI 639
Query: 729 EREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLV-SRTQ 787
E M L+ T VED+LQ T+E L AG+K+W+LTGDK+ETA + L + T+
Sbjct: 640 ETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTE 699
Query: 788 DIHIFRQVTSRGEA-----HLELNAFRRK-------------------HDCALVISGDSL 823
+ + + E H L +R+K + L+I G +L
Sbjct: 700 LLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTL 759
Query: 824 EVCLKY--------YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRR-TCAIGD 874
+ L Y+ F+++ +C AV+CCR +P QKA+IV +++ G T +IGD
Sbjct: 760 SLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGD 819
Query: 875 GGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQF 934
G NDVSMI + GIGI+GKEG+QA+ +D+S+ +F+H+ +LL+ HG Y R A L Q+
Sbjct: 820 GANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQY 879
Query: 935 VMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAM 993
++ L Q ++ F+ PLY + Y +T P+ + +L+Q + +
Sbjct: 880 FFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLT 939
Query: 994 LYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVH----------VV 1043
P LY ++ L FL W ++ ++G + +G LF++ +
Sbjct: 940 SDPRLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFG 999
Query: 1044 AISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFG-----IGRVSF 1098
I FT L+ T L +AL R W W+ + SL YV F + ++G +
Sbjct: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV----FFSFFWGGIIWPFLKQQR 1055
Query: 1099 GAFLDVAFITTVTFLWKVSAITVVSCLP---LYVLKYLRRK 1136
F+ +++V+ + + +S P L VLK +RR+
Sbjct: 1056 MYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLKNVRRR 1096
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 412 bits (1059), Expect = e-115
Identities = 314/1121 (28%), Positives = 526/1121 (46%), Gaps = 135/1121 (12%)
Query: 110 KKELKARTVWLGCPEKCE------EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFL 163
+K + RTV++G E ++ N I + KY ++ F+P L+EQF+ N YFL
Sbjct: 17 EKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFL 76
Query: 164 VISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRG 223
+I Q + T PL FV+ VT ++ +++ R + D EVN +
Sbjct: 77 IIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAK 135
Query: 224 KVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSC 283
+V+ +S I+VGD++ V+ ++ P D++ L + G+C++ T LDGE++ K AV
Sbjct: 136 RVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRD 195
Query: 284 TQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFT-REDSDPPIHESLSIENTLW-ASTIV 341
T L + ++ A + ++PQ D++ F G +S + SL EN L +T+
Sbjct: 196 TIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLK 255
Query: 342 ASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF 401
+ + GV +YTG ET+ +N K ++ +N L+ + V TL+ +
Sbjct: 256 NTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK-Y 314
Query: 402 VG--------PWYR-----------------NLFRFLLLFSYIIPISLRVNLDMGKAVYG 436
V PWY + F++LF++IIP+S+ V ++M K +
Sbjct: 315 VWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGS 374
Query: 437 WMMMKDENI------PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSY 490
+ + D++ G +V TS + EELG++ Y+ TDKTGTLT+N M F + Y
Sbjct: 375 FFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
Query: 491 GADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVL 550
T + SQ G T + K +R ++A+ L
Sbjct: 435 KGVTQEV----------DGLSQTDGTLTYFDKVDK-------------NREELFLRALCL 471
Query: 551 CHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDL 610
CH V ++ V TE AE TY +SSPDE+ALV+ + G T +
Sbjct: 472 CHTVE--IKTNDAVDGATESAEL---------TYISSSPDEIALVKGAKRYGFTFLGNRN 520
Query: 611 TSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYN 670
M+++ ++ + +L F + +RM VIV+ + +I + KGAD A+ P VQ +
Sbjct: 521 GYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNH 579
Query: 671 D--WLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESL 728
+ + A +G RTL VA K + + Y+ + +AK+++ DR K+ V + +
Sbjct: 580 EIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDI 639
Query: 729 EREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLV-SRTQ 787
E M L+ T VED+LQ T+E L AG+K+W+LTGDK+ETA + L + T+
Sbjct: 640 ETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTE 699
Query: 788 DIHIFRQVTSRGEA-----HLELNAFRRK-------------------HDCALVISGDSL 823
+ + + E H L +R+K + L+I G +L
Sbjct: 700 LLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTL 759
Query: 824 EVCLKY--------YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRR-TCAIGD 874
+ L Y+ F+++ +C AV+CCR +P QKA+IV +++ G T +IGD
Sbjct: 760 SLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGD 819
Query: 875 GGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQF 934
G NDVSMI + GIGI+GKEG+QA+ +D+S+ +F+H+ +LL+ HG Y R A L Q+
Sbjct: 820 GANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQY 879
Query: 935 VMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAM 993
++ L Q ++ F+ PLY + Y +T P+ + +L+Q + +
Sbjct: 880 FFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLT 939
Query: 994 LYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVH----------VV 1043
P LY ++ L FL W ++ ++G + +G LF++ +
Sbjct: 940 SDPRLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFG 999
Query: 1044 AISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFG-----IGRVSF 1098
I FT L+ T L +AL R W W+ + SL YV F + ++G +
Sbjct: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV----FFSFFWGGIIWPFLKQQR 1055
Query: 1099 GAFLDVAFITTVTFLWKVSAITVVSCLP---LYVLKYLRRK 1136
F+ +++V+ + + +S P L VLK +RR+
Sbjct: 1056 MYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLKNVRRR 1096
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 402 bits (1032), Expect = e-111
Identities = 319/1136 (28%), Positives = 527/1136 (46%), Gaps = 163/1136 (14%)
Query: 127 EEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPL 186
E K+ N+IK KYN FTFIP L+EQFK NLYFL + Q VP + YT PL
Sbjct: 89 ESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPL 148
Query: 187 GFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQV-KSSDIQVGDLIIVEKNQR 245
VL VT ++ +D+ R + DKE+N++ ++ G+ +V K +IQVGD+I ++KN
Sbjct: 149 LVVLGVTAIKDLVDDVARHKMDKEINNRT-CEVIKDGRFKVAKWKEIQVGDVIRLKKNDF 207
Query: 246 IPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQ-LPALGDLFSISAYVYAQK 304
+P+D++ L +SE C++ T +LDGET+ K K+++ T Q L L + ++ ++
Sbjct: 208 VPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEE 267
Query: 305 PQMDIHSFEGT-FTREDSDPPIHESLSIENTLWASTIVASGTVI-------GVVIYTGKE 356
P + F GT F R S P L A I+ G VI G+VI+ G +
Sbjct: 268 PNNRLDKFTGTLFWRNTSFP-----------LDADKILLRGCVIRNTDFCHGLVIFAGAD 316
Query: 357 TRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF----VG--------- 403
T+ + N+ + K +D +N + +F+ L+ LS + + VG
Sbjct: 317 TKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDG 376
Query: 404 ----PWYRNLFRF---LLLFSYIIPISLRVNLD---MGKAVY-GW---MMMKDENIPGTV 449
P YR F +++ + ++PISL V+++ +G++ + W M +++ P
Sbjct: 377 EDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAK- 435
Query: 450 VRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQM 509
RT+T+ E+LG++ Y+ +DKTGTLTQN M FK+ + YG D D Q H + Q+
Sbjct: 436 ARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYG-DHRDASQ-HNHNKIEQV 493
Query: 510 QSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETE 569
G +++ + + + +CH V
Sbjct: 494 DFSWNTYADGKLAFYD-HYLIEQIQSGKEPEVRQFFFLLAVCHTVM-------------- 538
Query: 570 FAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQ 629
D +D YQA+SPDE ALV + G ++R ++ + + G ++ +L
Sbjct: 539 -----VDRTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITI-SELGTERTYNVLA 592
Query: 630 LFPFTSESKRMGVIVRDESTAEITFYMKGADVA-------MSPIVQYNDWLEEECGNMAR 682
+ F S+ KRM +IVR I Y KGAD M+P Q ++ A
Sbjct: 593 ILDFNSDRKRMSIIVRTPE-GNIKLYCKGADTVIYERLHRMNPTKQET---QDALDIFAN 648
Query: 683 EGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVED 742
E LRTL + K + E+++ ++ ++ A ++ +R + V E +E+++ LL T +ED
Sbjct: 649 ETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIED 708
Query: 743 QLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAH 802
+LQ V T+ L A IKIW+LTGDK ETA I + L++ I + S A
Sbjct: 709 KLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHAR 768
Query: 803 LE-----------------LNAFRRKHDCALVISGD------------------------ 821
+E + F + AL+I+G
Sbjct: 769 MENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRT 828
Query: 822 ------------SLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRT 869
LE + + FV+LAC+C AV+CCR +P QKA +V L++++ T
Sbjct: 829 EEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAIT 888
Query: 870 CAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSA 929
AIGDG NDV+MI+ A G+GI G+EG QA +++D+S QFR++ RLL+VHGR SY R
Sbjct: 889 LAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMC 948
Query: 930 ALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVK 988
++ ++ + + +S +++ Y+ + + Y +YT PV + +LDQDV
Sbjct: 949 KFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVS 1008
Query: 989 PEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLF----------ESE 1038
++++ +P LY + ++K F + +L + IL + L + S+
Sbjct: 1009 DKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSD 1068
Query: 1039 FVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSF 1098
+ +AL++T + L W ++ + F S+ Y + F
Sbjct: 1069 YQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIM------FDFHSAGI 1122
Query: 1099 GAFLDVAFITTVT--------FLWKVSAITVVSC-LPLYVLKYLRRKLSPPSYCKL 1145
AF T T ++W +TV C LP+ +++L + P K+
Sbjct: 1123 HVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKI 1178
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 337 bits (863), Expect = 5e-92
Identities = 301/1124 (26%), Positives = 515/1124 (45%), Gaps = 162/1124 (14%)
Query: 128 EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLG 187
+K+ N I+ KYN ++F+P LYEQF NL+FL+I Q +P + ++ P+
Sbjct: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
Query: 188 FVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKSSDIQVGDLIIVEKNQRIP 247
+L + TR+ +D+ R + D+ +N++ L + Q K D+ VGD++ + K+ +P
Sbjct: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
Query: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCT-QQLPALGDLFSISAYVYAQKPQ 306
+DM+ L ++E + C++ T +DGET+ K + A+ T ++L + + S V + P
Sbjct: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
Query: 307 MDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVAS-GTVIGVVIYTGKETRSVMNTSN 365
+H F G D SL I N L + + T G+VIY G +T+ + N
Sbjct: 311 SRMHHFVGCLEWNDKK----YSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGK 366
Query: 366 PKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVGPWYRN----------------- 408
K LDL +N+L +F+++V + +V+ GF +++
Sbjct: 367 IHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAAES 426
Query: 409 ---LFRFLLLFSYIIPISLRVNLD---MGKAVY-GW---MMMKDENIPGTVVRTSTIPEE 458
+ FL+L S IP+S+ + + +G +V+ W M K +++P R++++ +
Sbjct: 427 FFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKA-RSTSLNDH 485
Query: 459 LGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNT 518
LG++ Y+ +DKTGTLTQN + F + + YG D+ E + +++ A G
Sbjct: 486 LGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDS--EATTRPKENPYLWNKFADGKL- 542
Query: 519 GSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFS 578
L + VR + + E + + +CH V + E+ DQ
Sbjct: 543 ----LFHNAALLHLVRTNGDEAVREFWRLLAICHTV---------MVRESPRERPDQ--- 586
Query: 579 DENRTYQASSPDEVALVQWTESVGLTLVSRD---LTSMQLKTPSGQVLSFCILQLFPFTS 635
YQA+SPDE ALV + G +SR +T M+L G+ + +L + F S
Sbjct: 587 ---LLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMEL----GEERVYQVLAIMDFNS 639
Query: 636 ESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLE----EECGNMAREGLRTLVVA 691
KRM V+VR A I Y KGAD + + +E E A+E LRTL +A
Sbjct: 640 TRKRMSVLVRKPEGA-ICLYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLA 698
Query: 692 KKALTEEQYQDFESRYTQAKLSMHDRS------LKVAAVVESLE------------REME 733
+ + E+ Y+D++ R+ +A L + +R+ L A+ + L+ ++
Sbjct: 699 YREVAEDIYEDWQQRHQEASLLLQNRAQALQQLLGATAIEDRLQDGVPETIKCLKKSNIK 758
Query: 734 LLCLTGVEDQLQADVRPTLEMLRNAGIKI------------W-----MLTGDKLETATCI 776
+ LTG + + ++ E+L + + W +LT + L
Sbjct: 759 IWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLA 818
Query: 777 AKSSH------LVSRTQDIHIFRQVTSRGEAHLELNAFRRKHDCALVISGDSLEVCLKY- 829
+ LVS ++ Q + EA EL RR A +S +C ++
Sbjct: 819 LVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYARRLS----LLCRRFG 874
Query: 830 --------------------YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRT 869
E FV+LA +C AV+CCR +P QKA IV L++++ T
Sbjct: 875 LPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYHQVVT 934
Query: 870 CAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSA 929
AIGDG ND++MI+ AD G+G+ G+EG QA +DF + QF + RLL+VHGR SY R
Sbjct: 935 LAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRIC 994
Query: 930 ALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVK 988
++ ++ + +Q F+ F PLY+G+ + + +Y+ PV + + +QDV
Sbjct: 995 KFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVS 1054
Query: 989 PEMAMLYPELY----KD-----------LTKGRSLSFKTFLIWVLISIYQGGILMYGALV 1033
E ++ PELY KD + G + S F + + IS G +
Sbjct: 1055 AEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSD-- 1112
Query: 1034 LFESEFVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGI 1093
F VVA+S I E++++ ++ W L V LSLG Y + + + F +
Sbjct: 1113 --HQSFAVVVALSCLLSITMEVILI---IKYWTALCVATILLSLGFY-AIMTTTTQSFWL 1166
Query: 1094 GRVSFGAF----LDVAFITTVTFLWKVSAITVVSCLPLYVLKYL 1133
RVS F D++ +++ + L V ++ P+ L+ +
Sbjct: 1167 FRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 273 bits (699), Expect = 5e-73
Identities = 197/624 (31%), Positives = 306/624 (49%), Gaps = 70/624 (11%)
Query: 557 VYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLK 616
+ ES +G + E D + Y+A SPDE ALV + TLVSR + ++
Sbjct: 690 ILESGSGTSLEEALEAPATDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVR 749
Query: 617 TPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQ-------- 668
P G L+F +L F S KRM V+VR T EI Y KGAD + +++
Sbjct: 750 LPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDI 809
Query: 669 --------YNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK 720
++ AR+GLRTL +AKK ++EE ++ + S +A+ S+ +R
Sbjct: 810 NMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDEL 869
Query: 721 VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS 780
+ + LE ++ LL TG+ED+LQ V T+ LR AGI++W+LTGDK ETA IA S
Sbjct: 870 LMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSC 929
Query: 781 HLVSRTQDIHIFR---QVTSRGEAHL---ELNAFRRKH---------------------- 812
L+++T ++ Q T + EL FR
Sbjct: 930 RLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEA 989
Query: 813 ---DCALVISGDSLEVCLK-YYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRR 868
+ LVI G +L + E +F+EL C +V+CCR +P QK+ IV L++
Sbjct: 990 VVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVM 1049
Query: 869 TCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRS 928
T +IGDG NDVSMIQAAD GIGI G+EG QA +++DF+IT+F+H+ +LL+VHG Y R
Sbjct: 1050 TLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRL 1109
Query: 929 AALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFP--VFSLVLDQD 986
A + + +++ + + + F+S + + M+ + +T P VF VLD+D
Sbjct: 1110 ARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFG-VLDKD 1168
Query: 987 VKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAIS 1046
+ E + PELYK + TF I ++ + YQ I + + ++ + V
Sbjct: 1169 ISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFG 1228
Query: 1047 F---TALILTELLMVALTVRTW---HWLMVVAEFLSLGCYVSSLAF----------LNEY 1090
T + T LL A+ ++TW H ++++ FL ++ SL + N Y
Sbjct: 1229 TPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMY--FLVSLLYNATCVICNSPTNPY 1286
Query: 1091 FGI-GRVSFGAFLDVAFITTVTFL 1113
+ + G++S F V F+T V L
Sbjct: 1287 WVMEGQLSNPTFYLVCFLTPVVAL 1310
Score = 157 bits (398), Expect = 4e-38
Identities = 124/459 (27%), Positives = 217/459 (47%), Gaps = 46/459 (10%)
Query: 124 EKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYW 183
E+ ++P N KY +FTF+P L+EQF + NLYFL + ++P++++ +
Sbjct: 60 EEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITM 119
Query: 184 APLGFVLAVTMTREAIDEFRRFQRDKEVNS---QLYSKLTVRGKVQVKSSDIQVGDLIIV 240
PL VL V M ++ +++F+R + DK +N ++Y + + VQ D++VGD I +
Sbjct: 120 LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYER-KEQTYVQKCWKDVRVGDFIQM 178
Query: 241 EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV 300
+ N+ +P+D++ L +S+ G C + T LDGET+ K + V Q + +
Sbjct: 179 KCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTI 238
Query: 301 YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV 360
+KP ++ F+G D S+ L TI + +G+VIY G ET+++
Sbjct: 239 VCEKPNNHLNKFKGYMEHPDQTRTGFGCESL--LLRGCTIRNTEMAVGIVIYAGHETKAM 296
Query: 361 MNTSNPKNKVGLLDLELN--------RLTKALFLALVALSIVMVT--------------- 397
+N S P+ K ++ +N L + V SI T
Sbjct: 297 LNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGS 356
Query: 398 -LQGFVGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKD------ENIPGTVV 450
L +G +Y L ++L +IPISL V++++ K + + D E
Sbjct: 357 FLPSALGGFYMFL-TMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQC 415
Query: 451 RTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYG-------ADTMDEIQSHVR 503
R I E+LG++ Y+ +DKTGTLT+N+M+F+R + Y +T E+ S
Sbjct: 416 RALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSD-G 474
Query: 504 DSYSQMQSQAGGNNTGSTP-LRKAQSSAPKVRKSVSSRI 541
+ ++Q Q + P ++Q A +R+S S+R+
Sbjct: 475 EEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARV 513
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 251 bits (641), Expect = 3e-66
Identities = 169/546 (30%), Positives = 273/546 (50%), Gaps = 50/546 (9%)
Query: 581 NRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKRM 640
N Y+A SPDE ALV + TL SR + + + L+F +L + PF S KRM
Sbjct: 720 NLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQLLHILPFDSVRKRM 779
Query: 641 GVIVRDESTAEITFYMKGADVAMSPIVQY---------------NDWLEEECGNMAREGL 685
V+VR + ++ Y KGAD + ++ + ++ + A++GL
Sbjct: 780 SVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGL 839
Query: 686 RTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQ 745
RTL +AKK +++ +Y ++ + A+ S+ +R + LE ++ LL TG+ED+LQ
Sbjct: 840 RTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQ 899
Query: 746 ADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAHLE- 804
V ++E L AGIKIWMLTGDK ETA IA + L+ + I + L
Sbjct: 900 EGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKDACGMLMS 959
Query: 805 --LNAFRRKHDC------------------------ALVISGDSLEVCLKY-YEHEFVEL 837
L ++K L+I+G +LE L+ + +F+EL
Sbjct: 960 TILKELQKKTQALPEQVSLSEDLLQPPVPRDSGLRAGLIITGKTLEFALQESLQKQFLEL 1019
Query: 838 ACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGK 897
C AVVCCR +P QK+ +V L++ H T AIGDG NDVSMIQ AD GIG+ G+EG
Sbjct: 1020 TSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVADIGIGVSGQEGM 1079
Query: 898 QASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFAS 957
QA +A+DF+++QF+H+ +LL+VHG Y R + + + ++ + + + F+
Sbjct: 1080 QAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLLFWYQFFCGFSG 1139
Query: 958 VPLYQGFLMVGYATIYTMF-PVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKTFLIW 1016
+ ++++ + ++T PV VL++DV E M PELY+ K + TF I
Sbjct: 1140 TSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKSEAYLPHTFWIT 1199
Query: 1017 VLISIYQGGILMYGALVLFESEFVHVVA----ISFTALILTEL-LMVALTVRTW-HWLMV 1070
+L + YQ + + ++ + A ++ AL + L L++ TW H L++
Sbjct: 1200 LLDAFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVI 1259
Query: 1071 VAEFLS 1076
+ LS
Sbjct: 1260 IGSILS 1265
Score = 160 bits (405), Expect = 6e-39
Identities = 120/426 (28%), Positives = 204/426 (47%), Gaps = 49/426 (11%)
Query: 124 EKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYW 183
EK + N I+ KY + F+P L+EQF NLYFL + +VP ++
Sbjct: 65 EKFSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITM 124
Query: 184 APLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKS--SDIQVGDLIIVE 241
PL VL + ++ ++++R+++ DK++N+ + + + K + D+ VGD I +
Sbjct: 125 LPLVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLS 184
Query: 242 KNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVY 301
N+ IP+DMV L +++ G C I T LDGE++ K + V + + D S+ +
Sbjct: 185 CNEVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIE 244
Query: 302 AQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLW-ASTIVASGTVIGVVIYTGKETRSV 360
+ P D+ F G + + LS EN L TI + V+G+V+Y G ET+++
Sbjct: 245 CESPNNDLSRFRGFLEHSNKE---RVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAM 301
Query: 361 MNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGFVG----------------- 403
+N S P+ K L+ N T L+ ++ +V++ L G VG
Sbjct: 302 LNNSGPRYKRSKLERRAN--TDVLWCVML---LVIMCLTGAVGHGIWLSRYEKMHFFNVP 356
Query: 404 --------PWYRNLFRF---LLLFSYIIPISLRVNLDMGKAVYGWMMMKD-----ENIPG 447
P + F ++L +IPISL V++++ K + + D E +
Sbjct: 357 EPDGHIISPLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDS 416
Query: 448 TV-VRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSY 506
V R I E+LG++ YL +DKTGTLT+N+M+F+R + G D E + +SY
Sbjct: 417 IVQCRALNIAEDLGQIQYLFSDKTGTLTENKMVFRRCSVA----GFDYCHEENARRLESY 472
Query: 507 SQMQSQ 512
+ S+
Sbjct: 473 QEAVSE 478
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 233 bits (595), Expect = 6e-61
Identities = 169/548 (30%), Positives = 266/548 (48%), Gaps = 52/548 (9%)
Query: 573 ADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFP 632
A + S+ Y+A SPDE ALV + LV R + ++ P L+F +L
Sbjct: 682 AQEQESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLG 741
Query: 633 FTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQ----------YNDWLEEECGNM-- 680
F S KRM V++R T EI Y KGAD + ++Q + + + N
Sbjct: 742 FDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLN 801
Query: 681 --AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLT 738
A EGLRTL +AK+ L++E+Y + + +A+ S+ + + LE + LL T
Sbjct: 802 VYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGAT 861
Query: 739 GVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSR 798
G+ED+LQ V T+ LR AG++IW+LTGDK ETA IA + L+ +++ +
Sbjct: 862 GIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQE 921
Query: 799 GEA--------HLELNAFRRKHD-------------C------------ALVISGDSLEV 825
A +++ +R + C +LVI G SL
Sbjct: 922 ACAALLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAY 981
Query: 826 CL-KYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQA 884
L K E +F+ LA QC +V+CCR +P QK+ +V L++ T AIGDG NDVSMIQ
Sbjct: 982 ALEKNLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQV 1041
Query: 885 ADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLIIST 944
AD G+GI G+EG QA +A+DF++ +FR++ RLL++HG Y R A + + ++ +
Sbjct: 1042 ADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVG 1101
Query: 945 MQAVFSSVFYF-ASVPLYQGFLMVGYATIYTMFPVFSLVLDQDVKPEMAMLYPELYKDLT 1003
+ F F AS + Q +L+ ++ P+ + VLD+DV + + P+LYK
Sbjct: 1102 LLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQ 1161
Query: 1004 KGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAIS---FTALILTELLMVAL 1060
+TF + + +Q + + + V + T +LT LL + +
Sbjct: 1162 NMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGI 1221
Query: 1061 TVRTWHWL 1068
+TW WL
Sbjct: 1222 ETKTWTWL 1229
Score = 162 bits (409), Expect = 2e-39
Identities = 115/401 (28%), Positives = 195/401 (48%), Gaps = 36/401 (8%)
Query: 126 CEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAP 185
C + N +K KY + +F+P L+EQF N+YF+ I+ FVPA+ AP
Sbjct: 55 CAQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAP 114
Query: 186 LGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKS--SDIQVGDLIIVEKN 243
+ F+LA+T R+ +++ R + D ++N + K V +I VGD + + N
Sbjct: 115 VLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCN 174
Query: 244 QRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQ 303
+ P+D++ L +S+ G C I T LDGET+ K + V +L + + + ++ + +
Sbjct: 175 EIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECE 234
Query: 304 KPQMDIHSFEGTFTREDSDPPIHESLSIENTLW-ASTIVASGTVIGVVIYTGKETRSVMN 362
KP D+ F G ++ L EN L T+ + V+G+VIY G ET++++N
Sbjct: 235 KPNNDLSRFRGCIIHDNGK---KAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLN 291
Query: 363 TSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF--------------------- 401
S P+ K L+ ++N L LV +S+ G
Sbjct: 292 NSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSS 351
Query: 402 VGPWYRNLFRFL---LLFSYIIPISLRVNLDMGKAVYGW-----MMMKDENIPGTV-VRT 452
+ P ++ FL ++ +IPISL V++++ KA + M + DE + R
Sbjct: 352 LSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRA 411
Query: 453 STIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGAD 493
I E+LG++ Y+ +DKTGTLT+N+M+F+R + V Y D
Sbjct: 412 LNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHD 452
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 142 bits (357), Expect = 2e-33
Identities = 92/322 (28%), Positives = 165/322 (51%), Gaps = 29/322 (9%)
Query: 129 KHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPLGF 188
++ N IK KYN+ TF+P L+EQF+ N YFL + Q +P + +T PL
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 189 VLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQVKS-SDIQVGDLIIVEKNQRIP 247
VL +T ++A D++ R + D +VN++ S++ + G +Q + ++ VGD+I +E NQ +
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVNNR-QSQVLINGILQQEQWMNVCVGDIIKLENNQFVA 146
Query: 248 SDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYVYAQKPQM 307
+D++ L +SE G C+I T +LDGET+ K++ A+ T +L + L V + P
Sbjct: 147 ADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNN 206
Query: 308 DIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGT-VIGVVIYTGKETRSVMNTSNP 366
+ F GT +++ P LS +N L ++ + G+VI+ G +T+ + N+
Sbjct: 207 KLDKFSGTLYWKENKFP----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
Query: 367 KNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF----VG-------PW---------- 405
K K +D +N L +F LV + +++ VG PW
Sbjct: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFS 322
Query: 406 -YRNLFRFLLLFSYIIPISLRV 426
+ + + ++++ + ++PISL V
Sbjct: 323 GFLSFWSYIIILNTVVPISLYV 344
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
Length = 1029
Score = 85.5 bits (210), Expect = 3e-16
Identities = 189/878 (21%), Positives = 322/878 (36%), Gaps = 188/878 (21%)
Query: 219 LTVRG--KVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWK 276
L +RG K+Q+ ++ +GDL+ ++ R+P+D+ + A C + L GE++
Sbjct: 178 LVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI----SAQGCKVDNSSLTGESE-- 231
Query: 277 LKVAVSCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLW 336
PQ S FT E+ L N +
Sbjct: 232 ----------------------------PQ----SRSPDFTHENP-------LETRNICF 252
Query: 337 ASTIVASGTVIGVVIYTGKET---RSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSI 393
ST GT G+VI TG T R TS + E+ + + V L +
Sbjct: 253 FSTNCVEGTARGIVIATGDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGV 312
Query: 394 VMVTLQGFVGPWYRNLFRFLL-LFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRT 452
L +G + FL+ + +P L + + + M + +V+
Sbjct: 313 TFFALSLLLGYGWLEAIIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKN----CLVKN 368
Query: 453 STIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQ 512
E LG + +DKTGTLTQN M + Y ADT +E
Sbjct: 369 LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEE--------------- 413
Query: 513 AGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAE 572
TG T + + + R AG+ +F +
Sbjct: 414 ----QTGKTFTKSSDTWFMLARI--------------------------AGLCNRADF-K 442
Query: 573 ADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFP 632
A+Q+ + E AL+++ E + M+ K P + P
Sbjct: 443 ANQEILPIAKRATTGDASESALLKFIEQS-----YSSVAEMREKNPK--------VAEIP 489
Query: 633 FTSESK-RMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVA 691
F S +K +M + +R++S+ MKGA + + E C G
Sbjct: 490 FNSTNKYQMSIHLREDSSQTHVLMMKGAP----------ERILEFCSTFLLNG------Q 533
Query: 692 KKALTEEQYQDFESRYTQAKLSMHDRSLKVAAV-------------VESLEREMELLCLT 738
+ ++ +E + F++ Y + + +R L + + + M+ LC
Sbjct: 534 EYSMNDEMKEAFQNAYLELG-GLGERVLGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFV 592
Query: 739 GVEDQL---QADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQV 795
G+ + +A V + R+AGIK+ M+TGD TA IAK ++S + +V
Sbjct: 593 GLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIIS--EGTETAEEV 650
Query: 796 TSRGEAHL-ELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQK 854
+R + + +++A K A+V+ G L+ + ++ P +V R SP QK
Sbjct: 651 AARLKIPISKVDASAAK---AIVVHGAELK---DIQSKQLDQILQNHPEIVFARTSPQQK 704
Query: 855 ARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGI--GIEGKE-GKQASLAADFSITQFR 911
IV Q+ G GDG ND ++ AD GI GI G + KQA+
Sbjct: 705 LIIVEGCQR-LGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA----------- 752
Query: 912 HIGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYAT 971
+L+ S G+ + L S M + S++ + + F+++G
Sbjct: 753 --DMILLDDNFASIVTGVEEGRLIFD-NLKKSIMYTLTSNI---PEITPFLMFIILGIPL 806
Query: 972 IYTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKT--FLIWVLISIYQGGILMY 1029
+ + L D+ P +++ Y D+ K + KT + LI + G I M
Sbjct: 807 PLGTITILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMI 866
Query: 1030 GALVLFESEFVHVVAISFTALILTELLMVALTVRTWHW 1067
AL F + FV + F + +LL + L HW
Sbjct: 867 QALAGFFTYFVILAENGFRPV---DLLGIRL-----HW 896
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 77.0 bits (188), Expect = 9e-14
Identities = 186/870 (21%), Positives = 319/870 (36%), Gaps = 192/870 (22%)
Query: 224 KVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSC 283
K+Q+ + ++ VGDL+ V+ R+P+D+ + + C + L GE++ + +
Sbjct: 175 KMQINAEEVVVGDLVEVKGGDRVPADLRIISSH----GCKVDNSSLTGESEPQTR----- 225
Query: 284 TQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVAS 343
P+ FT E+ L N + ST
Sbjct: 226 --------------------SPE---------FTHENP-------LETRNICFFSTNCVE 249
Query: 344 GTVIGVVIYTGKET---RSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQG 400
GT G+VI TG T R S + + +E+ + + V L + L
Sbjct: 250 GTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL 309
Query: 401 FVG-PWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTSTIPEEL 459
+G W + + + +P L + + + M + +V+ E L
Sbjct: 310 ILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKN----CLVKNLEAVETL 365
Query: 460 GRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTG 519
G + +DKTGTLTQN M + + ADT ++ Q+G
Sbjct: 366 GSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTED--------------QSGATFDK 411
Query: 520 STPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSD 579
+P A S AG+ F ++ S
Sbjct: 412 RSPTWTALSRI-------------------------------AGLCNRAVFKAGQENISV 440
Query: 580 ENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESK- 638
R A E AL++ E L + M+ + P + PF S +K
Sbjct: 441 SKRD-TAGDASESALLKCIE-----LSCGSVRKMRDRNPK--------VAEIPFNSTNKY 486
Query: 639 RMGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMAREGLRTLVVAKKALTEE 698
++ + R++S MKGA + + + C + LV K+ ++
Sbjct: 487 QLSIHEREDSPQSHVLVMKGAP----------ERILDRCSTI-------LVQGKEIPLDK 529
Query: 699 QYQD-FESRYTQAKLSMHDRSLKVAAV--------------VESLEREMELLCLTGVEDQ 743
+ QD F++ Y + + +R L + + L E LC G+
Sbjct: 530 EMQDAFQNAYMELG-GLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSM 588
Query: 744 L---QADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGE 800
+ +A V + R+AGIK+ M+TGD TA IAK ++S + + +R
Sbjct: 589 IDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE--TVEDIAAR-- 644
Query: 801 AHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTL 860
++ ++ + A V+ G L+ + E+ +V R SP QK IV
Sbjct: 645 LNIPMSQVNPREAKACVVHGSDLK---DMTSEQLDEILKNHTEIVFARTSPQQKLIIVEG 701
Query: 861 LQQHTGRRTCAIGDGGNDVSMIQAADCGI--GIEGKE-GKQAS----LAADF-SITQFRH 912
Q+ G GDG ND ++ AD GI GI G + KQA+ L +F SI
Sbjct: 702 CQRQ-GAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVE 760
Query: 913 IGRLLMVHGRNSYKRSAALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATI 972
GRL+ ++ K+S A L + + +F A++PL G +
Sbjct: 761 EGRLIF----DNLKKSIAY-------TLTSNIPEITPFLLFIIANIPLPLGTV------- 802
Query: 973 YTMFPVFSLVLDQDVKPEMAMLYPELYKDLTKGRSLSFKT--FLIWVLISIYQGGILMYG 1030
+ + L D+ P +++ Y D+ K + + +T + LIS+ G I M
Sbjct: 803 ----TILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQ 858
Query: 1031 ALVLFESEFVHVVAISFTALILTELLMVAL 1060
AL F F + V ++ + + LL + L
Sbjct: 859 ALGGF---FTYFVILAENGFLPSRLLGIRL 885
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 74.7 bits (182), Expect = 5e-13
Identities = 101/470 (21%), Positives = 183/470 (38%), Gaps = 99/470 (21%)
Query: 460 GRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTG 519
G+L + DKTGTLT++ G D M G
Sbjct: 500 GKLQLVCFDKTGTLTED--------------GLDVM-----------------------G 522
Query: 520 STPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSD 579
PL K Q+ P V + + ++A+ CH ++ + ++ G + + E+ +
Sbjct: 523 VVPL-KGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLE 581
Query: 580 ENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKR 639
E ++ +V L ++ L QL+ + +L FPF+S +R
Sbjct: 582 EEPAADSAFGTQV----------LAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQR 631
Query: 640 MGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMARE----GLRTLVVAKKAL 695
M V+V + Y+KG+ ++ + + + + M + G R + +A K L
Sbjct: 632 MSVVVAWPGATQPEAYVKGSPELVAGLCN-PETVPTDFAQMLQSYTAAGYRVVALASKPL 690
Query: 696 TEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEML 755
+ + T+ +++E ++ LL L + + L+ P ++ L
Sbjct: 691 PTVPSLEAAQQLTR----------------DTVEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
Query: 756 RNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQV-TSRGE-AHLE--------- 804
R I+ M+TGD L+TA +A+ +V+ + + I RG+ A LE
Sbjct: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 794
Query: 805 LNAFRRKHDCA------------LVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPT 852
+N + A L +SG + + +K++ ++ Q V R +P
Sbjct: 795 VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQ--GTVFARMAPE 852
Query: 853 QKARIVTLLQQHTGRRTCA--IGDGGNDVSMIQAADCGIGIEGKEGKQAS 900
QK +V LQ+ + C GDG ND ++AAD GI + E S
Sbjct: 853 QKTELVCELQK---LQYCVGMCGDGANDCGALKAADVGISLSQAEASVVS 899
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 74.7 bits (182), Expect = 5e-13
Identities = 101/470 (21%), Positives = 183/470 (38%), Gaps = 99/470 (21%)
Query: 460 GRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTG 519
G+L + DKTGTLT++ G D M G
Sbjct: 505 GKLQLVCFDKTGTLTED--------------GLDVM-----------------------G 527
Query: 520 STPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSD 579
PL K Q+ P V + + ++A+ CH ++ + ++ G + + E+ +
Sbjct: 528 VVPL-KGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLE 586
Query: 580 ENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKR 639
E ++ +V L ++ L QL+ + +L FPF+S +R
Sbjct: 587 EEPAADSAFGTQV----------LAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQR 636
Query: 640 MGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMARE----GLRTLVVAKKAL 695
M V+V + Y+KG+ ++ + + + + M + G R + +A K L
Sbjct: 637 MSVVVAWPGATQPEAYVKGSPELVAGLCN-PETVPTDFAQMLQSYTAAGYRVVALASKPL 695
Query: 696 TEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEML 755
+ + T+ +++E ++ LL L + + L+ P ++ L
Sbjct: 696 PTVPSLEAAQQLTR----------------DTVEGDLSLLGLLVMRNLLKPQTTPVIQAL 739
Query: 756 RNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQV-TSRGE-AHLE--------- 804
R I+ M+TGD L+TA +A+ +V+ + + I RG+ A LE
Sbjct: 740 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPMESPTA 799
Query: 805 LNAFRRKHDCA------------LVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPT 852
+N + A L +SG + + +K++ ++ Q V R +P
Sbjct: 800 VNGVKDPDQAASYTVEPDPRSRHLALSGPTFGIIVKHFPKLLPKVLVQ--GTVFARMAPE 857
Query: 853 QKARIVTLLQQHTGRRTCA--IGDGGNDVSMIQAADCGIGIEGKEGKQAS 900
QK +V LQ+ + C GDG ND ++AAD GI + E S
Sbjct: 858 QKTELVCELQK---LQYCVGMCGDGANDCGALKAADVGISLSQAEASVVS 904
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 73.2 bits (178), Expect = 1e-12
Identities = 157/716 (21%), Positives = 275/716 (38%), Gaps = 150/716 (20%)
Query: 223 GKVQVKSSDIQVGDLIIVEKNQRI-PSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAV 281
G +++S + GDL+I+ N+ + P D V + GSC + L GE+ K +
Sbjct: 271 GVQELESRVLVPGDLLILTGNKVLMPCDAVLIE-----GSCVVDEGMLTGESIPVTKTPL 325
Query: 282 SCTQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIV 341
P+MD S T+ ++D H + A
Sbjct: 326 -----------------------PKMD--SSVPWKTQSEADYKRHVLFCGTEVIQAKA-A 359
Query: 342 ASGTVIGVVIYTGKETRS---VMNTSNPKNKVGLLDLELNRLTKALFLALVALSIV--MV 396
SGTV VV+ TG T V + PK ++ +L R L LV + + +
Sbjct: 360 CSGTVRAVVLQTGFNTAKGDLVRSILYPKP----VNFQLYRDAIRFLLCLVGTATIGMIY 415
Query: 397 TLQGFV---GPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKDENIPGTVVRTS 453
TL +V P + + L + + +P +L L G +Y +K I +
Sbjct: 416 TLCVYVLSGEPPEEVVRKALDVITIAVPPALPAALTTG-IIYAQRRLKKRGIFCISPQRI 474
Query: 454 TIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQA 513
+ G+L + DKTGTLT++ G +G + D R+ + ++ S A
Sbjct: 475 NV---CGQLNLVCFDKTGTLTRD---------GLDLWGVVSCD------RNGFQEVHSFA 516
Query: 514 GGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEA 573
G PL A +S CH++ + + G + + EA
Sbjct: 517 SGQALPWGPLCAAMAS---------------------CHSLILLDGTIQGDPLDLKMFEA 555
Query: 574 DQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPF 633
T++ + + ++ + + +V T+ Q+ V IL FPF
Sbjct: 556 T--------TWEMAFSGDDFHIKGVPAHAM-VVKPCRTASQVP-----VEGIAILHQFPF 601
Query: 634 TSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYNDW---LEEECGNMAREGLRTLVV 690
+S +RM VIV++ + F MKGA ++ Q E +G R + +
Sbjct: 602 SSALQRMTVIVQEMGGDRLAF-MKGAPERVASFCQPETVPTSFVSELQIYTTQGFRVIAL 660
Query: 691 AKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRP 750
A K L + + +R E++E ++ L L +E++L+ + +P
Sbjct: 661 AYKKLENDHHATTLTR-------------------ETVESDLIFLGLLILENRLKEETKP 701
Query: 751 TLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEA--------- 801
LE L +A I+ M+TGD L+TA +A+ S +VS +Q + + + G +
Sbjct: 702 VLEELISARIRTVMITGDNLQTAITVARKSGMVSESQKVILIEANETTGSSSASISWTLV 761
Query: 802 ----HL-------------ELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAV 844
H+ E++ R+ ++G S V +++ ++
Sbjct: 762 EEKKHIMYGNQDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKILIN--GT 819
Query: 845 VCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGIEGKEGKQAS 900
+ R SP QK+ +V Q+ GDG ND ++ A GI + +E AS
Sbjct: 820 IFARMSPGQKSSLVEEFQK-LDYFVGMCGDGANDCGALKMAHVGISLSEQEASVAS 874
>gi|66730421 ATPase type 13A5 [Homo sapiens]
Length = 1218
Score = 68.9 bits (167), Expect = 3e-11
Identities = 84/359 (23%), Positives = 145/359 (40%), Gaps = 62/359 (17%)
Query: 616 KTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGAD-----VAMSPIVQYN 670
K+P +++ C FPF+S +RM VI + YMKGA S V N
Sbjct: 586 KSPVEAIITLC---QFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSETVPKN 642
Query: 671 DWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLER 730
+E + +G R + +A K L + E E +E
Sbjct: 643 --FPQELRSYTVQGFRVIALAHKTLKMGNLSEVEH-----------------LAREKVES 683
Query: 731 EMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIH 790
E+ L L +E++L+ + + L+ L A I+ M+TGD L+TA +AK+S ++ +
Sbjct: 684 ELTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVI 743
Query: 791 IF-------------------RQVTSRGEAHLELNAFRRK------HDC-ALVISGDSLE 824
I Q T G+ + ++ C +SG S +
Sbjct: 744 IVEADEPEEFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFAMSGKSYQ 803
Query: 825 VCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGNDVSMIQA 884
V +++ ++ V R SP QK+ ++ Q+ GDG ND ++A
Sbjct: 804 VIFQHFNSLLPKILVN--GTVFARMSPGQKSSLIEEFQK-LNYYVGMCGDGANDCGALKA 860
Query: 885 ADCGIGIEGKEGKQASLAADFS--ITQFRHIGRLLMVHGRNSYKRSAALGQFVMHRGLI 941
A GI + +E AS+A+ F+ T + + L+ GR + S + +++ G+I
Sbjct: 861 AHAGISLSEQE---ASVASPFTSKTTNIQCVPHLIR-EGRAALVSSFGVFKYLTMYGII 915
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
sapiens]
Length = 939
Score = 68.6 bits (166), Expect = 3e-11
Identities = 131/573 (22%), Positives = 212/573 (36%), Gaps = 134/573 (23%)
Query: 330 SIENTLWASTIVASGTVIGVVIYTGKET------RSVMNTSNPKNKVGLLDLELNRLTKA 383
S N + T+V G GVVI TG+ + + + PK L ++ L K
Sbjct: 212 SRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTP---LQKSMDLLGKQ 268
Query: 384 LFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYI-IPISLRVNLDMGKAVYGWMMMKD 442
L + +++ + +G +F + + IP L + + + A+ M+K
Sbjct: 269 LSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKK 328
Query: 443 ENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
+V+ I E LG + +DKTGTLT+NEM + T D + + V
Sbjct: 329 R----AIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIF---------TSDGLHAEV 375
Query: 503 RDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA 562
+ G N G + V + + V+A +C+
Sbjct: 376 --------TGVGYNQFGEVIV-----DGDVVHGFYNPAVSRIVEAGCVCN---------- 412
Query: 563 GVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQV 622
D N T P E AL+ +GL + +D
Sbjct: 413 -------------DAVIRNNTLMGK-PTEGALIALAMKMGLDGLQQD------------- 445
Query: 623 LSFCILQLFPFTSESKRMGV--IVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNM 680
+ +PF+SE K M V + R + +MKGA +++Y C
Sbjct: 446 --YIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGA---YEQVIKY-------CTTY 493
Query: 681 AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLER-EMELLCLTG 739
+G +TL LT++Q Y Q K M L+V A+ E ++ L L G
Sbjct: 494 QSKG-QTLT-----LTQQQ----RDVYQQEKARMGSAGLRVLALASGPELGQLTFLGLVG 543
Query: 740 VEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRG 799
+ D + V+ + L +G+ I M+TGD ETA IA L S+T
Sbjct: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----------- 592
Query: 800 EAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAV-VCCRCSPTQKARIV 858
+SG+ ++ + +L+ P V V R SP K +I+
Sbjct: 593 -----------------SVSGEEIDAM------DVQQLSQIVPKVAVFYRASPRHKMKII 629
Query: 859 TLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGI 891
LQ++ G GDG ND ++AAD G+ +
Sbjct: 630 KSLQKN-GSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
sapiens]
Length = 949
Score = 68.6 bits (166), Expect = 3e-11
Identities = 131/573 (22%), Positives = 212/573 (36%), Gaps = 134/573 (23%)
Query: 330 SIENTLWASTIVASGTVIGVVIYTGKET------RSVMNTSNPKNKVGLLDLELNRLTKA 383
S N + T+V G GVVI TG+ + + + PK L ++ L K
Sbjct: 212 SRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTP---LQKSMDLLGKQ 268
Query: 384 LFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYI-IPISLRVNLDMGKAVYGWMMMKD 442
L + +++ + +G +F + + IP L + + + A+ M+K
Sbjct: 269 LSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKK 328
Query: 443 ENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
+V+ I E LG + +DKTGTLT+NEM + T D + + V
Sbjct: 329 R----AIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIF---------TSDGLHAEV 375
Query: 503 RDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA 562
+ G N G + V + + V+A +C+
Sbjct: 376 --------TGVGYNQFGEVIV-----DGDVVHGFYNPAVSRIVEAGCVCN---------- 412
Query: 563 GVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQV 622
D N T P E AL+ +GL + +D
Sbjct: 413 -------------DAVIRNNTLMGK-PTEGALIALAMKMGLDGLQQD------------- 445
Query: 623 LSFCILQLFPFTSESKRMGV--IVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNM 680
+ +PF+SE K M V + R + +MKGA +++Y C
Sbjct: 446 --YIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGA---YEQVIKY-------CTTY 493
Query: 681 AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLER-EMELLCLTG 739
+G +TL LT++Q Y Q K M L+V A+ E ++ L L G
Sbjct: 494 QSKG-QTLT-----LTQQQ----RDVYQQEKARMGSAGLRVLALASGPELGQLTFLGLVG 543
Query: 740 VEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRG 799
+ D + V+ + L +G+ I M+TGD ETA IA L S+T
Sbjct: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----------- 592
Query: 800 EAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAV-VCCRCSPTQKARIV 858
+SG+ ++ + +L+ P V V R SP K +I+
Sbjct: 593 -----------------SVSGEEIDAM------DVQQLSQIVPKVAVFYRASPRHKMKII 629
Query: 859 TLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGI 891
LQ++ G GDG ND ++AAD G+ +
Sbjct: 630 KSLQKN-GSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
sapiens]
Length = 888
Score = 68.6 bits (166), Expect = 3e-11
Identities = 131/573 (22%), Positives = 212/573 (36%), Gaps = 134/573 (23%)
Query: 330 SIENTLWASTIVASGTVIGVVIYTGKET------RSVMNTSNPKNKVGLLDLELNRLTKA 383
S N + T+V G GVVI TG+ + + + PK L ++ L K
Sbjct: 212 SRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTP---LQKSMDLLGKQ 268
Query: 384 LFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYI-IPISLRVNLDMGKAVYGWMMMKD 442
L + +++ + +G +F + + IP L + + + A+ M+K
Sbjct: 269 LSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKK 328
Query: 443 ENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
+V+ I E LG + +DKTGTLT+NEM + T D + + V
Sbjct: 329 R----AIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIF---------TSDGLHAEV 375
Query: 503 RDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA 562
+ G N G + V + + V+A +C+
Sbjct: 376 --------TGVGYNQFGEVIV-----DGDVVHGFYNPAVSRIVEAGCVCN---------- 412
Query: 563 GVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQV 622
D N T P E AL+ +GL + +D
Sbjct: 413 -------------DAVIRNNTLMGK-PTEGALIALAMKMGLDGLQQD------------- 445
Query: 623 LSFCILQLFPFTSESKRMGV--IVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNM 680
+ +PF+SE K M V + R + +MKGA +++Y C
Sbjct: 446 --YIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGA---YEQVIKY-------CTTY 493
Query: 681 AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLER-EMELLCLTG 739
+G +TL LT++Q Y Q K M L+V A+ E ++ L L G
Sbjct: 494 QSKG-QTLT-----LTQQQ----RDVYQQEKARMGSAGLRVLALASGPELGQLTFLGLVG 543
Query: 740 VEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRG 799
+ D + V+ + L +G+ I M+TGD ETA IA L S+T
Sbjct: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----------- 592
Query: 800 EAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAV-VCCRCSPTQKARIV 858
+SG+ ++ + +L+ P V V R SP K +I+
Sbjct: 593 -----------------SVSGEEIDAM------DVQQLSQIVPKVAVFYRASPRHKMKII 629
Query: 859 TLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGI 891
LQ++ G GDG ND ++AAD G+ +
Sbjct: 630 KSLQKN-GSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
sapiens]
Length = 919
Score = 68.6 bits (166), Expect = 3e-11
Identities = 131/573 (22%), Positives = 212/573 (36%), Gaps = 134/573 (23%)
Query: 330 SIENTLWASTIVASGTVIGVVIYTGKET------RSVMNTSNPKNKVGLLDLELNRLTKA 383
S N + T+V G GVVI TG+ + + + PK L ++ L K
Sbjct: 212 SRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTP---LQKSMDLLGKQ 268
Query: 384 LFLALVALSIVMVTLQGFVGPWYRNLFRFLLLFSYI-IPISLRVNLDMGKAVYGWMMMKD 442
L + +++ + +G +F + + IP L + + + A+ M+K
Sbjct: 269 LSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKK 328
Query: 443 ENIPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHV 502
+V+ I E LG + +DKTGTLT+NEM + T D + + V
Sbjct: 329 R----AIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIF---------TSDGLHAEV 375
Query: 503 RDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRA 562
+ G N G + V + + V+A +C+
Sbjct: 376 --------TGVGYNQFGEVIV-----DGDVVHGFYNPAVSRIVEAGCVCN---------- 412
Query: 563 GVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQV 622
D N T P E AL+ +GL + +D
Sbjct: 413 -------------DAVIRNNTLMGK-PTEGALIALAMKMGLDGLQQD------------- 445
Query: 623 LSFCILQLFPFTSESKRMGV--IVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNM 680
+ +PF+SE K M V + R + +MKGA +++Y C
Sbjct: 446 --YIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGA---YEQVIKY-------CTTY 493
Query: 681 AREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLER-EMELLCLTG 739
+G +TL LT++Q Y Q K M L+V A+ E ++ L L G
Sbjct: 494 QSKG-QTLT-----LTQQQ----RDVYQQEKARMGSAGLRVLALASGPELGQLTFLGLVG 543
Query: 740 VEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRG 799
+ D + V+ + L +G+ I M+TGD ETA IA L S+T
Sbjct: 544 IIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----------- 592
Query: 800 EAHLELNAFRRKHDCALVISGDSLEVCLKYYEHEFVELACQCPAV-VCCRCSPTQKARIV 858
+SG+ ++ + +L+ P V V R SP K +I+
Sbjct: 593 -----------------SVSGEEIDAM------DVQQLSQIVPKVAVFYRASPRHKMKII 629
Query: 859 TLLQQHTGRRTCAIGDGGNDVSMIQAADCGIGI 891
LQ++ G GDG ND ++AAD G+ +
Sbjct: 630 KSLQKN-GSVVAMTGDGVNDAVALKAADIGVAM 661
>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
Length = 1158
Score = 68.6 bits (166), Expect = 3e-11
Identities = 96/449 (21%), Positives = 172/449 (38%), Gaps = 96/449 (21%)
Query: 460 GRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQMQSQAGGNNTG 519
G+L + DKTGTLT++ G D M G
Sbjct: 500 GKLQLVCFDKTGTLTED--------------GLDVM-----------------------G 522
Query: 520 STPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETEFAEADQDFSD 579
PL K Q+ P V + + ++A+ CH ++ + ++ G + + E+ +
Sbjct: 523 VVPL-KGQAFLPLVPEPRRLPVGPLLRALATCHALSRLQDTPVGDPMDLKMVESTGWVLE 581
Query: 580 ENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQLFPFTSESKR 639
E ++ +V L ++ L QL+ + +L FPF+S +R
Sbjct: 582 EEPAADSAFGTQV----------LAVMRPPLWEPQLQAMEEPPVPVSVLHRFPFSSALQR 631
Query: 640 MGVIVRDESTAEITFYMKGADVAMSPIVQYNDWLEEECGNMARE----GLRTLVVAKKAL 695
M V+V + Y+KG+ ++ + + + + M + G R + +A K L
Sbjct: 632 MSVVVAWPGATQPEAYVKGSPELVAGLCN-PETVPTDFAQMLQSYTAAGYRVVALASKPL 690
Query: 696 TEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVEDQLQADVRPTLEML 755
+ + T+ +++E ++ LL L + + L+ P ++ L
Sbjct: 691 PTVPSLEAAQQLTR----------------DTVEGDLSLLGLLVMRNLLKPQTTPVIQAL 734
Query: 756 RNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQV-TSRGE-AHLELNAFRRKHD 813
R I+ M+TGD L+TA +A+ +V+ + + I RG+ A LE +
Sbjct: 735 RRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHLIIVHATHPERGQPASLEFLPM----E 790
Query: 814 CALVISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCA-- 871
++G + V V R +P QK +V LQ+ + C
Sbjct: 791 SPTAVNGVKVLV----------------QGTVFARMAPEQKTELVCELQK---LQYCVGM 831
Query: 872 IGDGGNDVSMIQAADCGIGIEGKEGKQAS 900
GDG ND ++AAD GI + E S
Sbjct: 832 CGDGANDCGALKAADVGISLSQAEASVVS 860
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 68.6 bits (166), Expect = 3e-11
Identities = 179/848 (21%), Positives = 320/848 (37%), Gaps = 209/848 (24%)
Query: 226 QVKSSDIQVGDLIIVEKNQRI-PSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCT 284
++ S+D+ GD++++ N I P D V + G+C + L GE+ V V+ T
Sbjct: 283 EIFSTDLVPGDVMVIPLNGTIMPCDAVLIN-----GTCIVNESMLTGES-----VPVTKT 332
Query: 285 QQLPALGDLFSISAYVYAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASG 344
LP P +D+ E +P H+ +TL+ T
Sbjct: 333 N-LP---------------NPSVDVKGIGD----ELYNPETHK----RHTLFCGT----- 363
Query: 345 TVIGVVIYTGKETRSVMNTSNPKNKVGLL----------DLELNRLTKALFLALVALSIV 394
TVI YTG+ ++++ + G L D +L R L LVA++ +
Sbjct: 364 TVIQTRFYTGELVKAIVVRTGFSTSKGQLVRSILYPKPTDFKLYRDAYLFLLCLVAVAGI 423
Query: 395 MVTLQGFVGPWYRNLFR----------FLLLFSYIIPISLRVNLDMGKAVYGWMMMKDEN 444
GF+ ++ L + + +P +L + G VY +K
Sbjct: 424 -----GFIYTIINSILNEVQVGVIIIESLDIITITVPPALPAAMTAG-IVYAQRRLKKIG 477
Query: 445 IPGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRD 504
I + I G+L + DKTGTLT++ G +G ++ + +
Sbjct: 478 IFCISPQRINI---CGQLNLVCFDKTGTLTED---------GLDLWGIQRVENARFLSPE 525
Query: 505 SYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGV 564
N + L K+Q V + CH++T + +G
Sbjct: 526 E-----------NVCNEMLVKSQF----------------VACMATCHSLTKIEGVLSGD 558
Query: 565 TEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQ--- 621
+ + EA +E ++ +E AL + T+V + TP+G
Sbjct: 559 PLDLKMFEAIGWILEE------ATEEETAL---HNRIMPTVVRPPKQLLPESTPAGNQEM 609
Query: 622 -------VLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPI-------V 667
I++ FPF+S +RM V+ R ++ YMKGA A++ + V
Sbjct: 610 ELFELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAIAGLCKPETVPV 669
Query: 668 QYNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVES 727
+ + LE+ ++G R + +A + L ES+ T K+ R ++
Sbjct: 670 DFQNVLED----FTKQGFRVIALAHRKL--------ESKLTWHKVQNISR--------DA 709
Query: 728 LEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQ 787
+E M+ + L ++++L+ + LE L A I+ M+TGD + TA +A+ ++
Sbjct: 710 IENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQD 769
Query: 788 DIHIFRQVTSRGEAHLELN---------------------AFRRKHDCA---------LV 817
+ I + + ++N + HD
Sbjct: 770 KVIIAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQMTRYHFA 829
Query: 818 ISGDSLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRTCAIGDGGN 877
++G S V L++++ +L V R +P QK +++ L Q+ GDG N
Sbjct: 830 MNGKSFSVILEHFQDLVPKLMLH--GTVFARMAPDQKTQLIEAL-QNVDYFVGMCGDGAN 886
Query: 878 DVSMIQAADCGIGIEGKEGKQASLAADF-SITQFRHIGRLLMVHGRNSYKRSAALGQFVM 936
D ++ A GI + E AS+A+ F S T L+ GR + S + +F+
Sbjct: 887 DCGALKRAHGGISLSELE---ASVASPFTSKTPSISCVPNLIREGRAALITSFCVFKFM- 942
Query: 937 HRGLIISTMQAVFSSVFYFASVPLYQ--------GFLMVGYATIYTMFPVFSLVLDQDVK 988
A++S + YF+ LY FL + A I + VF++ L+ K
Sbjct: 943 ----------ALYSIIQYFSVTLLYSILSNLGDFQFLFIDLAIILVV--VFTMSLNPAWK 990
Query: 989 PEMAMLYP 996
+A P
Sbjct: 991 ELVAQRPP 998
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,972,481
Number of Sequences: 37866
Number of extensions: 1626966
Number of successful extensions: 4341
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3983
Number of HSP's gapped (non-prelim): 198
length of query: 1147
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1034
effective length of database: 13,968,660
effective search space: 14443594440
effective search space used: 14443594440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.